LOCUS       BGC0000444             20623 bp    DNA     linear   BCT 04-FEB-2005
DEFINITION  Streptomyces turgidiscabies pathogenicity island putative
            transposase gene, complete cds; fas operon, complete sequence; and
            putative methyltransferases, putative transmembrane transport
            protein, hypothetical protein (fas6), putative transposase, nitric
            oxide synthase (nos), and putative cytochrome P450 genes, putative
            transposase pseudogenes, putative araC family regulatory protein
            gene, putative transposase pseudogene, thaxtomin synthetase A
            (txtA), thaxtomin synthetase B (txtB), and cytochrome P450 (txtC)
            genes, complete cds.
ACCESSION   BGC0000444
VERSION     BGC0000444
KEYWORDS    .
SOURCE      Streptomyces turgidiscabies Car8
  ORGANISM  Streptomyces turgidiscabies Car8
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 19:25:16
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20623
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[10209:19082]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10210..19082
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..20623
                     /SMILES="NC(Cc1ccccc1)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..20623
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000444"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..20623
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..1203)
                     /gene="nos"
                     /locus_tag="stPAI021"
     CDS             complement(1..1203)
                     /codon_start=1
                     /gene="nos"
                     /locus_tag="stPAI021"
                     /product="nitric oxide synthase"
                     /protein_id="AAW49313.1"
                     /transl_table=11
                     /translation="MTFEVALGPSLPAPSPTACPALAHDSPLSPVPSAEPATSQDCGVA
                     DPDEAEEFLRQFHAEQSDQAVPLTRRLDQVRAAIDATGTYRHTTAELVFGARVAWRNSS
                     RCIGRLYWNSLRVLDRRDTTAPEVIHRHLCTHLRQATNGGRIRPVISVFAPDAPSRPGP
                     RVWNEQLVRYAGHRRDDGTVLGDPRSADLTEAIRGLGWQGGRQGPFDVLPLVIDAHDDK
                     PRFFELPREVVLEVPITHPDVPRLAELCLRWHAVPVISNMRLRIGGVDYPLAPFNGWYM
                     GTEIGVRNLVDEARYNLLPAVAACLQLDTTSESTLWRDRALVELNVAVLHSFAAAGVRI
                     SDHHEESRRFLAHLTKEERQGRTVPADWSWIVPPLSSGITPVFHRYYDNADQRPNFYPH
                     Q"
     gene            complement(1235..2455)
                     /locus_tag="stPAI022"
     CDS             complement(1235..2455)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 267.6; E-value: 2.9e-81)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="stPAI022"
                     /product="putative cytochrome P450"
                     /protein_id="AAW49314.1"
                     /sec_met_domain="p450 (E-value: 2.1e-18, bitscore: 55.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALSPLADPSIVADPYPVYADLVRRDPIHWVERLNAWAVLPYAE
                     CAAGLKDPQFTADRGTEVLAAKFPGQPLPPESIFHRWTKNVVMYTDPPLHDALRRSVHA
                     GFTRSAHQHYDQVIQKAAHDLVASIPAGATEIDAVPALAAQLPLRAAVHAFGVPEEDLG
                     FLIPRVETIMTYHSGPKDQPVTQGTVMEQLTDLHTYAFELLRGMRGKVLPDTVIARLAA
                     AQDGLTETTPEQTVHQLALVFIALFAPTTPGSLSSGMLAFARNPQQIERFLADQACVDN
                     TANEVLRYNASNQFTWRVAATDVDMGGVQIKAGQAVALFLGAANRDPDMFERPHDFDLG
                     RPNSGRHLSFGQGVHACLAAQIVSLQLKWFYVALLGRFPGVRPSGQPIWNENLEFRSLR
                     SLPLSLR"
     gene            3134..3367
                     /locus_tag="stPAI023"
                     /pseudo=""
     CDS             3134..3367
                     /codon_start=1
                     /locus_tag="stPAI023"
                     /note="putative transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="TVSKALVDQGFKDQVVARGVGLRIDVEIVARNPQVKGFVPQPKRW
                     RVEQTYGILILHRRLVCDYEHSPSSSASRVYWA"
     gene            3706..4470
                     /locus_tag="stPAI024"
     CDS             3706..4470
                     /codon_start=1
                     /locus_tag="stPAI024"
                     /product="putative transposase"
                     /protein_id="AAW49315.1"
                     /transl_table=11
                     /translation="MLVYPSGVNVSSSTLRFLATRLRERRRSLGTRWRRLNAGRQALLT
                     LAHLRNGQPYAQLAAGFGIGTTTAYRYIAEAVELLAALAPTLAEAVRAASTKAYLILDG
                     TLLPIDRIAADRPFYSGKHKKHGMNVQVIADPKGRLLWASPALAGAVHDVRAAREHGII
                     DALAEAGINCWADKGYQGAGGTVRVPYRGRWDSLSAGQQAVNRSHAKVRALVXQAIATL
                     KSWRLLRKLRCSTTRITSLVQXVLTLHLASSD"
     gene            complement(4583..4802)
                     /locus_tag="stPAI025"
                     /pseudo=""
     CDS             complement(4583..4802)
                     /codon_start=1
                     /locus_tag="stPAI025"
                     /note="putative transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="ELEEDPAAFAVAALHRWWTEEGRAAYPDARRLLITADGGGSNSSR
                     ARAWKANLAVLATETGLEISVCHLPPGT"
     gene            4963..6186
                     /locus_tag="stPAI026"
     CDS             4963..6186
                     /codon_start=1
                     /locus_tag="stPAI026"
                     /product="putative transposase"
                     /protein_id="AAW49316.1"
                     /transl_table=11
                     /translation="MSTERAVKVWAGWFDDFFASLAGVFGRVEPRRMAMAYVKALVAPV
                     ERKNGWQIAEHVGHPSPDRVQWFLARSTWCADQLRDALRSFVVQFLARPDGVLVLDETA
                     FLQKGRMSAGEAPQYAGITGQIENCQVAVFCAYATDTGRGLIDRELYLPAAWCANADRC
                     RTQHIPRARAKAVVTKPELGRRMVERCRRAKVPFGWVAADSAYGQDRKLRAALERRRIP
                     YVMAVPVDETVSTHGTGPWREDKLAAGIPLIFERRSCGVGAKGLRSYDWALADVTWPGG
                     AEGGPRRGHVHLLRVRRSISDPGQVAYFAVHAKAGTPIGEIVRVMGLRWSIEDCFETAK
                     SDCGLDHYEVRTWDAWHRHITLSMAALAFLTITDTRSRHLQEPDEHDLLPAPVPAPEKG
                     ARRAALKS"
     gene            complement(6538..7176)
                     /locus_tag="stPAI027"
     CDS             complement(6538..7176)
                     /codon_start=1
                     /locus_tag="stPAI027"
                     /note="start codon unclear"
                     /product="putative araC family regulatory protein"
                     /protein_id="AAW49317.1"
                     /transl_table=11
                     /translation="MNDGSVPFSIYVPVAARFLVLRFIEAAKDGLPMSPRGTFGVVNLT
                     KDPGSGFLLSSLNALAAEMMKTDFILPPGMREVVRILAASAMRTAYIELGKQHSGGFDP
                     LLIAVQESIDRQLADPEISPATFAAEHNISVRQLHRIFESIGESSMSYVKRRRLERFAC
                     DLRNPSLRHRKINELAADWGMLDAAMLSKNFSSAYGMSPRAYRKQYCPT"
     gene            complement(8688..9892)
                     /locus_tag="stPAI028"
                     /pseudo=""
     CDS             8688..9892
                     /codon_start=1
                     /gene="pseudo21222_22427"
                     /note="putative transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="SSETWGSGFVEGAVAEHREQHADPLSGEAKEGPGYGIFRGRSRCG
                     RRDRAGRRTRTGTMRA"
     misc_feature    9762..9764
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10210..14568
                     /gene="txtA"
                     /locus_tag="stPAI029"
     CDS             10210..14568
                     /NRPS_PKS="Domain: AMP-binding (22-421). E-value: 1.4e-104.
                     Score: 341.8. Matches aSDomain:
                     nrpspksdomains_stPAI029_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (511-732). E-value: 2.9e-118. Score:
                     386.7. Matches aSDomain: nrpspksdomains_stPAI029_nMT.1"
                     /NRPS_PKS="Domain: PCP (934-1002). E-value: 7.5e-22. Score:
                     69.2. Matches aSDomain: nrpspksdomains_stPAI029_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1019-1319). E-value:
                     3.8e-87. Score: 283.9. Matches aSDomain:
                     nrpspksdomains_stPAI029_Condensation_LCL.1"
                     /codon_start=1
                     /gene="txtA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 60; E-value: 4e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="stPAI029"
                     /product="thaxtomin synthetase A"
                     /protein_id="AAW49318.1"
                     /sec_met_domain="Condensation (E-value: 2.1e-57, bitscore:
                     183.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7.7e-119, bitscore:
                     386.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.7e-16, bitscore:
                     50.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHLTGGDRPEGALATTWPSLLEAWAADTPDAIALVTADTALTYA
                     QFNARANRLARWLKHLGAGPERSVGLVLGRSADFFLCATAVLKCGAAYLPLDPSYPMER
                     LSFMTRDAAPVALVTTSDVPGELLDQLSTRRLVSLDDEVAEDALRRLPDHDMEDGERLE
                     PLRPASPAYIIYTSGSTGIPKGVVVTHQGVASLIATQRRRLAVTGVSRVLAFSSPSFDA
                     SFWEMSMALLTGAALVVGRPGRLLPDTELAALIADQGVTHLTLPPSVAGSLDPGMLPPG
                     VTLVVAGEACPAALVQRWRPHRTMVNAYGPTESTVCATMSDPLADDMAPPVGRAVDGTR
                     IHVLDDRLAPVVSGAVGEIFIAGHSLARGYLKRPGLTAQRFVADPFGPAGSRMYRSGDL
                     GRWTRSGELEFVGRADDQVKVRGFRIEPGEIESVLAGCRGVRQAAVVVREDRPGEPYLA
                     AYVVPENEAADETAEEELDGRLAAWRRLYDDLYDRADTPDFGEDFSGWVSSYGGRPIEG
                     MREWRAQTVQQIRELAPRRVLEIGCGSGLLLSQLAGDCESYWGTDISGALIERLRGQVA
                     ERPGLADRVVLHRLSAHELGGLPRSGFDTVVLNSVIQYFPSGDYLFDVLREVSGLLAPG
                     GAVFLGDVRNLRLLRTFHTGGLLASASPADIPETVCAAIDRAMAQERELLVDPEFFATV
                     VGALPGMTLESCTLKRGGYDNELSRYRYEVVLRKHAGPADDPGPVVRLPWDGGTASLAG
                     VADWLRRGKPERVCVTGIPNGRVAGEHAATLALFDRRPLPEVLSLGQVPAGVAPEDLRQ
                     LGAELGYRVDCAWSSENDALIDASFTLAGTLVPRPAPRTDAKPDDFSPARFTNRPAFAR
                     PDSRTMASLPGQVAAQLPAFMVPEVFVPLDRLPVTVNGKLDRAALPRPQRAAPAAGRPP
                     KTAREEVLAAIFADVLATADVTADSDFFATGGNSLLATRLAAEVRHRLDTEMPLSWLFE
                     SPTVEALAARFDAEDEARPVPVPGEYASGSTAPLSAQQLQMWDEYRQSLHRDMFNVPLS
                     LRLTGAVDAEALRAALADVVTRHVPLRTLVRDDGSGPCAVITEATADDIPWTQTRTTPK
                     RLPEDLAHAARRHFDLETEIPLRAAHFTLGPNESVLLLVMHHIAADGWSFGPLQEDLVR
                     AYRSRTEGHAPQWEPLSLGYLDYVAWQRRLLGSPDDPSDVALRQAEYWRKTLHGADDRP
                     VLETDSPAPSRQDFAGRSLDLPLEVGGHRVLTAAAREHGVTVFMILHAALVAMLARKGA
                     GGDITVTTAVAGRTDTQFEPLVGLFANTLALRIDTSGNPTFRELLYRVRVTDLAAYAHQ
                     DLLFEHLADMPSPQVSLVLRTVAAPPSDLPGLTLAPGPRPASESARYPVLWTVEHLAST
                     ADSGTLRSHIQYQSGLLRDDTVARIAQRYEVVLSLLLKDPDLRVQDLPPQ"
     aSDomain        10276..11472
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stPAI029_AMP-binding.1"
                     /evalue="1.40E-104"
                     /label="stPAI029_AMP-binding.1"
                     /locus_tag="stPAI029"
                     /protein_end="421"
                     /protein_start="22"
                     /score="341.8"
                     /specificity="consensus: phe"
                     /tool="antismash"
                     /translation="EAWAADTPDAIALVTADTALTYAQFNARANRLARWLKHLGAGPER
                     SVGLVLGRSADFFLCATAVLKCGAAYLPLDPSYPMERLSFMTRDAAPVALVTTSDVPGE
                     LLDQLSTRRLVSLDDEVAEDALRRLPDHDMEDGERLEPLRPASPAYIIYTSGSTGIPKG
                     VVVTHQGVASLIATQRRRLAVTGVSRVLAFSSPSFDASFWEMSMALLTGAALVVGRPGR
                     LLPDTELAALIADQGVTHLTLPPSVAGSLDPGMLPPGVTLVVAGEACPAALVQRWRPHR
                     TMVNAYGPTESTVCATMSDPLADDMAPPVGRAVDGTRIHVLDDRLAPVVSGAVGEIFIA
                     GHSLARGYLKRPGLTAQRFVADPFGPAGSRMYRSGDLGRWTRSGELEFVGRADDQVKVR
                     "
     aSModule        10276..13215
                     /complete
                     /domains="nrpspksdomains_stPAI029_AMP-binding.1"
                     /domains="nrpspksdomains_stPAI029_nMT.1"
                     /domains="nrpspksdomains_stPAI029_PCP.1"
                     /locus_tags="stPAI029"
                     /monomer_pairings="phe -> NMe-phe"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       10462..10500
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI029_0001"
                     /evalue="1.00E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="stPAI029"
                     /protein_end="97"
                     /protein_start="84"
                     /score="15.6"
                     /tool="antismash"
                     /translation="AVLKCGAAYLPLD"
     CDS_motif       10720..10779
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI029_0002"
                     /evalue="6.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="stPAI029"
                     /protein_end="190"
                     /protein_start="170"
                     /score="30.9"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGIPKGVVVTH"
     CDS_motif       10891..10932
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI029_0003"
                     /evalue="8.60E+00"
                     /label="Cy4"
                     /locus_tag="stPAI029"
                     /protein_end="241"
                     /protein_start="227"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="SMALLTGAALVVGR"
     CDS_motif       11269..11352
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI029_0004"
                     /evalue="3.10E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="stPAI029"
                     /protein_end="381"
                     /protein_start="353"
                     /score="45.0"
                     /tool="antismash"
                     /translation="GAVGEIFIAGHSLARGYLKRPGLTAQRF"
     CDS_motif       11437..11502
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI029_0005"
                     /evalue="7.40E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="stPAI029"
                     /protein_end="431"
                     /protein_start="409"
                     /score="40.3"
                     /tool="antismash"
                     /translation="FVGRADDQVKVRGFRIEPGEIE"
     aSDomain        11743..12405
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stPAI029_nMT.1"
                     /domain_subtype="nMT"
                     /evalue="2.90E-118"
                     /label="stPAI029_nMT.1"
                     /locus_tag="stPAI029"
                     /protein_end="732"
                     /protein_start="511"
                     /score="386.7"
                     /tool="antismash"
                     /translation="GRPIEGMREWRAQTVQQIRELAPRRVLEIGCGSGLLLSQLAGDCE
                     SYWGTDISGALIERLRGQVAERPGLADRVVLHRLSAHELGGLPRSGFDTVVLNSVIQYF
                     PSGDYLFDVLREVSGLLAPGGAVFLGDVRNLRLLRTFHTGGLLASASPADIPETVCAAI
                     DRAMAQERELLVDPEFFATVVGALPGMTLESCTLKRGGYDNELSRYRYEVVLRKHAGP"
     aSDomain        13012..13215
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stPAI029_PCP.1"
                     /evalue="7.50E-22"
                     /label="stPAI029_PCP.1"
                     /locus_tag="stPAI029"
                     /protein_end="1002"
                     /protein_start="934"
                     /score="69.2"
                     /tool="antismash"
                     /translation="EEVLAAIFADVLATADVTADSDFFATGGNSLLATRLAAEVRHRLD
                     TEMPLSWLFESPTVEALAARFDA"
     CDS_motif       13018..13050
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI029_0006"
                     /evalue="1.10E-01"
                     /label="Cy4"
                     /locus_tag="stPAI029"
                     /protein_end="947"
                     /protein_start="936"
                     /score="5.7"
                     /tool="antismash"
                     /translation="VLAAIFADVLA"
     aSDomain        13267..14166
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stPAI029_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="3.80E-87"
                     /label="stPAI029_Condensation_LCL.1"
                     /locus_tag="stPAI029"
                     /protein_end="1319"
                     /protein_start="1019"
                     /score="283.9"
                     /tool="antismash"
                     /translation="TAPLSAQQLQMWDEYRQSLHRDMFNVPLSLRLTGAVDAEALRAAL
                     ADVVTRHVPLRTLVRDDGSGPCAVITEATADDIPWTQTRTTPKRLPEDLAHAARRHFDL
                     ETEIPLRAAHFTLGPNESVLLLVMHHIAADGWSFGPLQEDLVRAYRSRTEGHAPQWEPL
                     SLGYLDYVAWQRRLLGSPDDPSDVALRQAEYWRKTLHGADDRPVLETDSPAPSRQDFAG
                     RSLDLPLEVGGHRVLTAAAREHGVTVFMILHAALVAMLARKGAGGDITVTTAVAGRTDT
                     QFEPLVGLFANTLALRIDT"
     CDS_motif       13330..13437
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI029_0007"
                     /evalue="2.30E-12"
                     /label="C2_DCL_024-062"
                     /locus_tag="stPAI029"
                     /protein_end="1076"
                     /protein_start="1040"
                     /score="39.2"
                     /tool="antismash"
                     /translation="DMFNVPLSLRLTGAVDAEALRAALADVVTRHVPLRT"
     CDS_motif       13648..13713
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI029_0008"
                     /evalue="3.60E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="stPAI029"
                     /protein_end="1168"
                     /protein_start="1146"
                     /score="32.3"
                     /tool="antismash"
                     /translation="MHHIAADGWSFGPLQEDLVRAY"
     CDS_motif       13765..13800
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI029_0009"
                     /evalue="4.00E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="stPAI029"
                     /protein_end="1197"
                     /protein_start="1185"
                     /score="10.0"
                     /tool="antismash"
                     /translation="YLDYVAWQRRLL"
     CDS_motif       14068..14157
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI029_0010"
                     /evalue="4.80E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="stPAI029"
                     /protein_end="1316"
                     /protein_start="1286"
                     /score="38.3"
                     /tool="antismash"
                     /translation="DITVTTAVAGRTDTQFEPLVGLFANTLALR"
     gene            14565..19082
                     /gene="txtB"
                     /locus_tag="stPAI030"
     CDS             14565..19082
                     /NRPS_PKS="Domain: AMP-binding (49-448). E-value: 7.5e-102.
                     Score: 332.8. Matches aSDomain:
                     nrpspksdomains_stPAI030_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (537-757). E-value: 2.2e-115. Score:
                     377.2. Matches aSDomain: nrpspksdomains_stPAI030_nMT.1"
                     /NRPS_PKS="Domain: PCP (964-1029). E-value: 3.4e-20. Score:
                     63.9. Matches aSDomain: nrpspksdomains_stPAI030_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1047-1349). E-value:
                     7.5e-102. Score: 332.2. Matches aSDomain:
                     nrpspksdomains_stPAI030_Condensation_LCL.1"
                     /codon_start=1
                     /gene="txtB"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 57.8; E-value:
                     1.9e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="stPAI030"
                     /product="thaxtomin synthetase B"
                     /protein_id="AAW49319.1"
                     /sec_met_domain="Condensation (E-value: 4.2e-65, bitscore:
                     209.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6.7e-116, bitscore:
                     376.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.8e-15, bitscore:
                     45.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPRASPSDPILCEVHSMSTLPPGRSRTTAPPAGPQASPEFTPDL
                     WGRLFEARVDADPESTAINSASDRLSYAELNWRANRLARLLVAHGAGPESLVGIALPRS
                     TDFVVAVAAVLKSGAAYFPLDPEYPPQRLAFMLADAAPLLVLTRSDIEPELPAEAASRT
                     VVLDDPAVVRTLTDRSAADVTDDERVAPLRTWHPAYVIYTSGSTGTPKGVVLTHHGIAG
                     LVGSHARDLGIGASSRLLLFSSPSFDGAFWDVSMALLTGATLVVAPRERLLPGPEFSAL
                     VAEEGITHFALSASTLSALPDGALPAGATVVNVGEACNGELVRRWSPGRLMVNAYGPTE
                     STVSATMSGPLAAEGMPPIGRPLSDTRVHVLDERLRPVPPGAVGEIHIAGAGLARGYLG
                     RPALTAERFVADPFGAPGKRMYRTGDLARVRDDGQLEFVGRVDDQAKIRGFRVEPGEVE
                     AMLRDHPEVAQAAVLVREDTPGDQRLVAYVVPDHPAVRQXDGTASEHVGEWQRLYDEVY
                     STVGALPLGEDFSGWNSSYDGDPIPLPQMRAWRDATVDSIRALRPRRVLEIGVGTGLLL
                     SHLAGDCEAYWATDFSTEVIEALGKKVDGDPVVRETVXLRPGPAHNLPGLPEGYFDTVV
                     LNSVIQYFPSADYLVSVLREAVRLVAPGGRVFVGDVRHLRLLRPLRSAVRLRSAIGREV
                     SASDVRAAVDQDLMDEKELLLDPAFFTVVSRWIPQIRGVRTAVKRGTHHNELTRYRYDA
                     VLIKEPVKTGTVAPDARTLTWGTDVGGLQPLSGLLARIRTPLLLRGVPNSRILAEVSAA
                     AALATAPSLDEPSRLLREPATGIDPEELHALGEGAGYEVHLTWSAQDPTRVDARFTPAG
                     GEPDAVPPADSADSVRTSPGDHANQPTTHRTGMALMSKLPGYLAARLPAYLRPSALVRV
                     ESLPLTVNGKLDRAALPPPLLFPQADGQAPRTPREEILTHLFADVLGLPGVPRDADFFA
                     LGGNSLLATRLVGRIAKHLEVDVPIAWVFETPTVEGLAGRTAPTSRFRRRLVCRDEHHT
                     AVPLSHSQYGMWFINQLGGPASRIYNVPYCLRLTGRVDSAALRIALDDVVARHEPLRTV
                     FPDDGDGPRQRVLAPEDAVVVLHETDTFEDRLAGELSRAAAEPFELRTDLPLRARLFRH
                     GQDRSTLLLLMHHITVDAWSLAPLTADLTRAYRARLGQRAPQWQPLPVHYRDYAVWHNA
                     QVAGTQDRSSGFGRGLAFWERMLRGLPVEMQLPVDRRRPARPTYRGGTVHTRIEASLHQ
                     ELLNCARETGATPFMVLHAALAALLTRLGGGTDIVVGTAAAARTDPALDDLVGLFANSV
                     VLRVDTSGDPTFRTLLARARAVDLDAFTHQEVPFDQVVDLLNPARHPARHPLYQTALVL
                     HTPPGDGHRAHLVTLTPEPPPDTGTARFDLMFNWDENRDSAGLAQGLTGRTEYSSDLFS
                     QETVELLLERYVLLLSAVVREPDTRLHTLNILTEPERQAFSRRP"
     aSDomain        14712..15908
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stPAI030_AMP-binding.1"
                     /evalue="7.50E-102"
                     /label="stPAI030_AMP-binding.1"
                     /locus_tag="stPAI030"
                     /protein_end="448"
                     /protein_start="49"
                     /score="332.8"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEARVDADPESTAINSASDRLSYAELNWRANRLARLLVAHGAGPE
                     SLVGIALPRSTDFVVAVAAVLKSGAAYFPLDPEYPPQRLAFMLADAAPLLVLTRSDIEP
                     ELPAEAASRTVVLDDPAVVRTLTDRSAADVTDDERVAPLRTWHPAYVIYTSGSTGTPKG
                     VVLTHHGIAGLVGSHARDLGIGASSRLLLFSSPSFDGAFWDVSMALLTGATLVVAPRER
                     LLPGPEFSALVAEEGITHFALSASTLSALPDGALPAGATVVNVGEACNGELVRRWSPGR
                     LMVNAYGPTESTVSATMSGPLAAEGMPPIGRPLSDTRVHVLDERLRPVPPGAVGEIHIA
                     GAGLARGYLGRPALTAERFVADPFGAPGKRMYRTGDLARVRDDGQLEFVGRVDDQAKIR
                     "
     aSModule        14712..17651
                     /complete
                     /domains="nrpspksdomains_stPAI030_AMP-binding.1"
                     /domains="nrpspksdomains_stPAI030_nMT.1"
                     /domains="nrpspksdomains_stPAI030_PCP.1"
                     /locus_tags="stPAI030"
                     /monomer_pairings="X -> NMe-X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       14901..14939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI030_0001"
                     /evalue="4.90E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="stPAI030"
                     /protein_end="125"
                     /protein_start="112"
                     /score="13.6"
                     /tool="antismash"
                     /translation="AVLKSGAAYFPLD"
     CDS_motif       15156..15215
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI030_0002"
                     /evalue="1.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="stPAI030"
                     /protein_end="217"
                     /protein_start="197"
                     /score="33.1"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVVLTH"
     CDS_motif       15699..15788
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI030_0003"
                     /evalue="2.20E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="stPAI030"
                     /protein_end="408"
                     /protein_start="378"
                     /score="55.1"
                     /tool="antismash"
                     /translation="PPGAVGEIHIAGAGLARGYLGRPALTAERF"
     CDS_motif       15873..15938
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI030_0004"
                     /evalue="3.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="stPAI030"
                     /protein_end="458"
                     /protein_start="436"
                     /score="35.1"
                     /tool="antismash"
                     /translation="FVGRVDDQAKIRGFRVEPGEVE"
     aSDomain        16176..16835
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stPAI030_nMT.1"
                     /domain_subtype="nMT"
                     /evalue="2.20E-115"
                     /label="stPAI030_nMT.1"
                     /locus_tag="stPAI030"
                     /protein_end="757"
                     /protein_start="537"
                     /score="377.2"
                     /tool="antismash"
                     /translation="GDPIPLPQMRAWRDATVDSIRALRPRRVLEIGVGTGLLLSHLAGD
                     CEAYWATDFSTEVIEALGKKVDGDPVVRETVXLRPGPAHNLPGLPEGYFDTVVLNSVIQ
                     YFPSADYLVSVLREAVRLVAPGGRVFVGDVRHLRLLRPLRSAVRLRSAIGREVSASDVR
                     AAVDQDLMDEKELLLDPAFFTVVSRWIPQIRGVRTAVKRGTHHNELTRYRYDAVLIK"
     aSDomain        17457..17651
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stPAI030_PCP.1"
                     /evalue="3.40E-20"
                     /label="stPAI030_PCP.1"
                     /locus_tag="stPAI030"
                     /protein_end="1029"
                     /protein_start="964"
                     /score="63.9"
                     /tool="antismash"
                     /translation="EEILTHLFADVLGLPGVPRDADFFALGGNSLLATRLVGRIAKHLE
                     VDVPIAWVFETPTVEGLAGR"
     aSDomain        17706..18611
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stPAI030_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="7.50E-102"
                     /label="stPAI030_Condensation_LCL.1"
                     /locus_tag="stPAI030"
                     /protein_end="1349"
                     /protein_start="1047"
                     /score="332.2"
                     /tool="antismash"
                     /translation="TAVPLSHSQYGMWFINQLGGPASRIYNVPYCLRLTGRVDSAALRI
                     ALDDVVARHEPLRTVFPDDGDGPRQRVLAPEDAVVVLHETDTFEDRLAGELSRAAAEPF
                     ELRTDLPLRARLFRHGQDRSTLLLLMHHITVDAWSLAPLTADLTRAYRARLGQRAPQWQ
                     PLPVHYRDYAVWHNAQVAGTQDRSSGFGRGLAFWERMLRGLPVEMQLPVDRRRPARPTY
                     RGGTVHTRIEASLHQELLNCARETGATPFMVLHAALAALLTRLGGGTDIVVGTAAAART
                     DPALDDLVGLFANSVVLRVDT"
     CDS_motif       17778..17891
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI030_0005"
                     /evalue="9.20E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="stPAI030"
                     /protein_end="1109"
                     /protein_start="1071"
                     /score="53.4"
                     /tool="antismash"
                     /translation="IYNVPYCLRLTGRVDSAALRIALDDVVARHEPLRTVFP"
     CDS_motif       18093..18158
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI030_0006"
                     /evalue="1.00E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="stPAI030"
                     /protein_end="1198"
                     /protein_start="1176"
                     /score="21.3"
                     /tool="antismash"
                     /translation="MHHITVDAWSLAPLTADLTRAY"
     CDS_motif       18207..18239
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI030_0007"
                     /evalue="6.50E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="stPAI030"
                     /protein_end="1225"
                     /protein_start="1214"
                     /score="9.4"
                     /tool="antismash"
                     /translation="HYRDYAVWHNA"
     CDS_motif       18513..18602
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI030_0008"
                     /evalue="2.60E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="stPAI030"
                     /protein_end="1346"
                     /protein_start="1316"
                     /score="39.1"
                     /tool="antismash"
                     /translation="DIVVGTAAAARTDPALDDLVGLFANSVVLR"
     CDS_motif       18651..18770
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stPAI030_0009"
                     /evalue="1.10E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="stPAI030"
                     /protein_end="1402"
                     /protein_start="1362"
                     /score="49.9"
                     /tool="antismash"
                     /translation="RAVDLDAFTHQEVPFDQVVDLLNPARHPARHPLYQTALVL"
     gene            19436..20623
                     /gene="txtC"
                     /locus_tag="stPAI031"
     CDS             19436..20623
                     /codon_start=1
                     /gene="txtC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 372.4; E-value:
                     4.2e-113)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="stPAI031"
                     /product="cytochrome P450"
                     /protein_id="AAW49320.1"
                     /sec_met_domain="p450 (E-value: 6.5e-27, bitscore: 83.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESTPDQAHPTNSPLEPYHIYPEARSCPVAKVSLWNGTPAHVFSG
                     HDEVRTVLQDRRFSSDSRRPNFTELTPTLQSQAAQPPFVRTDNPDHRRLRGTVAREFLP
                     KRIELLRPAIREIVQGVLDRLAETAPPQDMFEAFAVPVASATVFRLLGIPAEDRALLTR
                     CVKGVVSAVGSEDEGAEVFRILGEYIGGLVQDSSALPEDSMIRRLVEGPYSAKELTFHE
                     AIGVILMLIVGGYDTTASTISLSLVSYALHPEKFSFVHERPERIPMLVEELLRYHTVAQ
                     LGLGRIATADVEVGSVTVRAGEMVVAALSLANRDKSVFPNPDKLDFDRPSVPHVGFGYG
                     PHQCVGQALARVELQEAIPAVIRRLPGLRLACTLEDLPFRHDMSTYGVHELPMTW"
ORIGIN
        1 tcactgatga gggtaaaagt tggggcgctg gtcggcgttg tcgtagtagc ggtggaagac
       61 gggggtgatg ccgctggaaa gcggagggac gatccagctc cagtccgcgg gtacggtgcg
      121 gccctggcgt tcctccttgg tcaggtgggc gaggaagcgc cgggactcct cgtggtggtc
      181 actgatccgg acgcctgcgg ccgcgaaaga gtgcaagacg gcaacgttga gttcgaccag
      241 agcgcggtca cgccacaggg tggactcgct ggtggtgtcc aactggaggc aggcggccac
      301 ggcggggagc aggttgtagc gggcctcgtc gacgaggtta cggacgccga tctccgtgcc
      361 catgtaccag ccgttgaacg gggcgagggg gtagtccacc ccgccgatac gcaggcgcat
      421 gttggagata acgggtacgg cgtgccagcg caggcagagt tcggccagtc gtgggacgtc
      481 ggggtgggtg atagggacct ccaggacaac ctcccgcggc agctcgaaga accgcggttt
      541 gtcgtcgtgg gcgtcgatga ccaggggcag gacgtcgaac ggcccttggc ggcctccctg
      601 ccatccgagg ccgcggatgg cctcggtgag gtcggcagat cgcgggtcgc cgagtacggt
      661 gccgtcgtcg cgacggtggc cggcgtaccg gacgagttgc tcgttccaca cccgcgggcc
      721 gggtcggctg ggtgcgtccg gggcgaagac cgaaatcacc ggcctgatac gcccaccgtt
      781 ggtcgcctgg cgcaggtgcg tgcaaaggtg ccggtggatt acctcggggg ctgtggtgtc
      841 ccggcggtcc aggacgcgca ggctgttcca gtacaggcgg ccgatacagc gactggagtt
      901 gcgccacgcg acacgggcac cgaacacgag ctcggcggtg gtatgacggt aggtgcccgt
      961 ggcgtcgatg gcagcgcgaa cctggtccag gcgccgagtg agcgggacgg cctggtcgga
     1021 ctgctccgcg tgaaactggc gcaggaactc ctcggcctcg tctggatcgg cgacgccgca
     1081 gtcctgcgac gtcgccggtt ccgccgacgg gacgggactg aggggcgaat cgtgcgccag
     1141 cgccgggcac gctgtcgggg acggggcggg caaggaaggg cccagggcga cttcgaaagt
     1201 cacgattcct cgcaggggta gagcgccagc ctcgtcagcg gaggctgagc ggcagtgagc
     1261 ggagagagcg gaactcgagg ttctcgttcc agatcggctg gcccgacggc cggacgcccg
     1321 ggaagcggcc cagcagggct acgtagaacc acttcaactg cagggaaacg atctgcgcgg
     1381 cgagacaggc gtgcaccccc tggccgaacg acaggtgccg accactgttg ggacggccga
     1441 ggtcgaaatc gtgcggcctc tcgaacatgt cggggtcccg gttggccgcg cccaggaaca
     1501 gggcgacggc ctgccctgcc ttgatctgta cgccgcccat gtcgacgtcc gtggccgcga
     1561 cgcgccatgt gaactggttt gaggcgttgt agcggaggac ctcgttggcc gtattgtcca
     1621 cacatgcctg gtccgccagg aagcgttcga tctgctgcgg gttgcgggcg aacgcgagca
     1681 tgccgctact gagggagccc ggcgtcgtgg gtgcgaacaa cgcgatgaac accagcgcca
     1741 gttgatgcac ggtttgttcc ggcgtggtct cggtcagacc atcctgggcg gccgccaggc
     1801 gggcgatgac ggtgtccggt aggaccttac cccgcatgcc ccggaggagt tcgaaggcgt
     1861 acgtgtgtag gtcggtgagc tgttccataa ctgtcccctg ggtcaccggc tggtctttcg
     1921 gaccggagtg gtacgtcatg atcgtctcca cgcgcggaat gaggaatccg aggtcctcct
     1981 cggggactcc gaaggcgtgc acggcagcgc gtagggggag ttgggcagcc agggcgggga
     2041 cggcgtcgat ctcggtggca ccggccggga ttgaagcgac caggtcgtgc gcggccttct
     2101 ggatgacctg gtcgtagtgc tggtgcgcgg aacgggtgaa gcccgcgtgg acggaccggc
     2161 gcagagcgtc gtggagcggc gggtccgtat acatcaccac gttcttggtc cagcggtgga
     2221 agatgctctc cggcggcagt ggctgcccgg ggaacttcgc ggccagcact tctgtccccc
     2281 ggtcggcggt gaactgggga tccttcagcc cggcggcgca ctctgcgtac ggcagtaccg
     2341 cccaggcatt caggcgctcg acccagtgga tggggtcgcg ccggaccagg tcggcgtaga
     2401 cggggtaggg gtcggccacg atggacgggt ccgcgagtgg cgagagggcg gtcacgggag
     2461 ctccttgggg tagtcgaaaa ggaatgcgga ggcggggggc gcggcaggga ttccagaaag
     2521 cgcaggaggc gagcatctcg atcccgtggt cgtcagccgc agcgcatagg tgctgacaag
     2581 gcggcaacgc gacatcgccg ggcgggctct ccagcgacag acgagcctga ccacggggcg
     2641 gaggaagcct gtggcgagcg gcgacgattt ataggtgaag cagccgacag gggaccacgc
     2701 tcacccgggt tgcctgtcct ggtgacgcag ccgccgtagt accggaattc tctctactga
     2761 aggtcacgcg ttggcacgcc ttcatcatgg ataggcgtgc cccgtgaaat cttgtcgatc
     2821 gacgaccgat acctagctgt tggatgccag ttctgctacc ggtactgcgg ttgaactcgc
     2881 agcgaggctg cgccatgctc gttttcgcag ttcagcggag ctcccggaac accgcgaggc
     2941 gtggcaaatt aacccgaacc ggacggcatc tgactacgcg aaaccctgtc gtacggccgg
     3001 cccgacccgc cgtcagccca cgccgccgcc gaatgcaacg aacaacctta cgcctctttc
     3061 ggtacctcct cgggcaggat gcccgggcgg ggctggggcc aggggccgtt gcgtgatcga
     3121 gcacgccgcc ataaccgtca gcaaagccct ggtcgaccag ggcttcaagg atcaggtcgt
     3181 cgcacgcggc gtcggcctga gaattgacgt cgagatagtc gcacgcaacc cgcaggtcaa
     3241 ggggttcgtg ccgcagccga agcggtggag ggtcgagcag acctacggga tcctgatact
     3301 gcaccggcgc ttggtctgcg actacgagca cagtccctcc tcttccgcct cccgcgtcta
     3361 ctgggcgatg acccacgtca tgacccgacg cctcaccggc gcgcgcgcca ccgcctgtgc
     3421 cgcggcgcag gcggtggcag tgtgaacatc cggcccctgc tcgatgccct ggacctccag
     3481 gaagacgctg cccgggccct ggccgacaac ctccgcgcac agatcgacgg cctgcagacc
     3541 cggttacggg aggccgagac gcacctggag cacctcacga tcacccgcaa gaccgtgagc
     3601 ctttttcaac ctctcgcgtc ggctgggcag ttggcctgac aaacaggtga agcccctggt
     3661 agatgggttt tcgaccaaga gaaccgtctc caccagaggc ttcgcatgct tgtctacccg
     3721 tccggcgtca acgtgtccag ctctaccctc cgcttcctcg ccacccgcct gagagaacgt
     3781 cggcgctctc tcggcacgcg gtggcggcgt ctgaatgcgg gccgacaggc cctgctcacc
     3841 ctcgcccacc tccgcaacgg ncagccctac gcgcagctcg cagccggttt cgggatcggc
     3901 accaccaccg cctaccggta catcgcggag gctgtcgagc tcctggcggc cctcgccccc
     3961 acgctcgccg aagcagtacg ggccgcgtcg acgaaggcgt acctgatcct cgacgggacg
     4021 cttctgccga tcgaccggat cgctgccgac cgccccttct attcaggaaa acacaagaag
     4081 cacggcatga acgtgcaggt catagccgat ccgaagggcc gtctcctgtg ggcttcaccg
     4141 gccctggccg gtgccgtcca tgacgtgcgg gccgcccgcg agcacggcat catcgacgct
     4201 ctcgccgagg ccggcatcaa ctgctgggca gacaagggat accagggcgc aggcggcacg
     4261 gtccgtgtcc cttaccgagg ccgatgggac agcctctccg ccggccagca ggccgtcaac
     4321 cggtcccatg cgaaggtccg ggcactggtc naacaagcca tcgccaccct caaatcctgg
     4381 cggctcctgc gtaagctccg ctgctcgacg acccggatca cgagcctcgt ccaanccgtc
     4441 ctcaccctcc atctggccag ctcagactga ggatggaaaa ggctcactgt gtggcgccac
     4501 ttcttcctcg tttccttgtt caggacaacc ctattgggtg cctgtccgga aacttcgtgg
     4561 cccctcatca agcaacggca ttgtgtgccc ggcggcaggt ggcacacgct gatctccaga
     4621 cccgtctcgg tggccagtac ggcgaggttg gccttccagg cccgggcgcg ggagctgttc
     4681 gagccgccgc cgtccgcggt gatcagaagt ctgcgcgcgt cggggtaggc cgccctgcct
     4741 tcctccgtcc accagcggtg cagggccgcg accgcgaacg cggcgggatc ctcctccagc
     4801 tcggccagtc cgcgggagac gcaacccttg gagactccgg ccgccttcgc gacggcggcg
     4861 atcccgccgt gaccgagtat ccgggcctcc gccccgtaca acaggtacta cagccgtgac
     4921 tcgtgtccgt gtccggtggc cgtgtgatgc gttgacctgt ccgtgagtac ggagcgggct
     4981 gtaaaagtct gggcgggctg gttcgatgac ttcttcgcct ctttggcggg tgtcttcggg
     5041 cgggtcgagc cgcggcggat ggcgatggcc tatgtgaagg ctctggtggc gccggtcgag
     5101 cgcaagaacg ggtggcagat cgccgagcac gtcgggcacc cgagtccgga ccgggtccag
     5161 tggtttctgg cccgctcgac atggtgcgcg gatcaactcc gtgacgccct gcggtcgttc
     5221 gttgtccagt tcctggcccg gccggacggg gtgctggtac tggacgagac ggcgttcttg
     5281 cagaagggcc ggatgtcggc cggggaggcc ccgcagtacg ccgggatcac cggccagatc
     5341 gagaactgcc aggtcgcggt gttctgcgcg tacgccaccg acaccggacg cgggctgatc
     5401 gaccgcgagt tgtacctgcc cgccgcctgg tgcgccaacg ccgaccgctg ccgcacccag
     5461 cacattcccc gagcgcgcgc gaaggcggtg gtgaccaaac cggaactggg ccggcgcatg
     5521 gtcgagcggt gccgccgggc caaagtgccc ttcggctggg tggccgccga cagcgcctac
     5581 ggccaggacc gcaaactccg tgccgcactc gaacgccgcc gcatccccta tgtgatggcc
     5641 gtcccggtgg acgagacggt gtccacccat ggcaccgggc cttggcgcga ggacaagctg
     5701 gccgctggta tcccgctgat cttcgaacgc cgctcctgcg gcgtgggcgc caagggcctg
     5761 cgctcctacg actgggcact ggccgacgtc acctggcccg gcggcgccga aggcggcccc
     5821 cggcgcggcc atgtccactt gctgcgggtc aggcgctcga tctccgaccc cggccaggtc
     5881 gcctacttcg ccgtgcacgc caaagccggc accccgatcg gcgagatcgt ccgcgtgatg
     5941 gggctgcgct ggtccatcga agactgtttt gagaccgcga agtccgactg cggcctggac
     6001 cactacgagg tccgcacctg ggacgcctgg caccgccaca tcaccctttc gatggcggcc
     6061 ctcgccttcc tcacgatcac tgacacccgc agccgccacc tccaggaacc cgacgagcac
     6121 gacctattgc ccgcaccggt cccggcgccc gaaaaggggg cccgtcgggc cgcgttgaaa
     6181 agctgatccg gctacaccgc cgaggagatc cgccgcctgc tcaaccggct cgtatgggcc
     6241 accacacagc caccaccggc gatcgtgatc atccagtcac gctggcgccg aacccaccaa
     6301 gcacgcgcac aacgctgcca ctacgccacc cgcgacaaac gagatcgcga gtcacggctg
     6361 tagtacaggc ggcgctgacg ctcgttgagg tgcggcgcca ctgcttccag cttcgcccgt
     6421 aacgggccga tcaactcatc gaaacgtccc ataccacatc aacgatccga aatcctggaa
     6481 gcaacccgga gataatcgac gccccccccg gccagtcgcc gccacgccct cgccatttca
     6541 ggtggggcag tactgcttcc gataggcacg gggagacatt ccgtaggctg agctgaagtt
     6601 tttactcagc atcgcggcat ccaacatccc ccagtccgcc gccaattcgt tgatctttcg
     6661 gtgcctcagg ctcggattcc ttaggtcgca tgcgaaacgc tccaggcgac ggcgtttgac
     6721 gtagctcatg ctactttccc cgatcgattc gaaaatgcga tgcaactgac gcaccgatat
     6781 attatgttcg gccgcgaagg tcgccgggct gatctcagga tcagccaatt gccggtcgat
     6841 cgactcctga acggcgatca gaagtgggtc gaatccccca gagtgttgct tgccgagctc
     6901 gatatatgcg gttctcatcg ccgaggccgc taggatgcgc acgacctctc tcataccagg
     6961 gggtagaata aaatcggttt tcatcatctc tgcagccagg gcattcaagg atgaaagaag
     7021 aaatccggat ccgggatctt tggtaagatt taccacgccg aaagttcccc gaggcgacat
     7081 cgggagcccg tccttcgccg cctcgatgaa acgcagcacg aggaatcgcg ccgcaaccgg
     7141 cacatagatc gaaaatggaa cactgccgtc gttcatggcc agcatccccg cgccgatctc
     7201 cgaattttcc ttgccatgcg tgatacatgc aaggcccgac agtgcacata cgactgtccg
     7261 ctgtggcaaa gtcgcctccg aacttactgc ctcgaactca atgatggctt taccagaatc
     7321 tacggctgtc gcctggattt cgcacgcctc gaaatatttt acctgaatgc ctgagctcga
     7381 taagagacgg tactttgcgt tcggcacgtt gttcgggaat cgagtaaagg tggaattctc
     7441 cccctcctcg actgcgagcg cgacaaacag ttcaggaaca atcatgtcga gaccctccgc
     7501 aggtaacgaa tccggccgcc cacctgccat atttgcttga aatttcaatc tttaggtcat
     7561 tcgggtccgc catcgagagc gagaaaaccc tgttggcaac ctgcctgtgg gcgaaatacc
     7621 ggacgcagat cagatgtgat gacactccgc tgcgaacgtc ttcgtctcga gcgcgcggac
     7681 acttggatcg gatttcggcg gcctactcat cacctcagca cgccacagaa acattcccgt
     7741 atgccgcagt cggcctctcc ggaaacagca cagagggggg aatgccgtct ctgtgatcgg
     7801 gtttccggat cagcctgagg ggaacttctc atcgggtttt ccatactcgt cacgagcgca
     7861 cgaccgaccg caactagaca gatgccgtgc gtgtcgtcgc gtgctggcaa aatttgactc
     7921 caccgttgcc caccaggagg ggtactgcgc cgtacgtgag agcaccgtgg gagcgctccc
     7981 gtattgacca tgcactgcgg ttggcagccc agtcaagtac ctcatgattg acttttcttc
     8041 ttcattgacc gaaccttcca ttcgttgacc aaataagcgg agagcgcccc tgaactgcaa
     8101 cgatggaatt tgtctagacc gcacctcgcg aatctgcaga gtcaccgtca gccctctgac
     8161 gatgactcat gaacaatcaa ggtagccgga gtctgtgtgg ccaactcccc ggggtatgac
     8221 cagggacatt gtcctgtcgg gcggtgcgta agcttcggcg ggattggtgg cggatccata
     8281 tgccctactc attggactcg gctgccggct ttgccctgcc aactgcccac ccaaccgcac
     8341 ttacgcgcca cgctggaggg tgcattttga gacagcggcc cgccgggcag gcggagtcgt
     8401 cgagcgcaag cgccgccgat tcggaagtcg caggcagctc ctgttttccc ctggtcgcgg
     8461 gaggccacta tccccgtttg ttagccgaac tctttcggtt gcggcgaggc ggcaggagcc
     8521 gtacgtggat taccgtctca ccgttgccaa agaggaagct tggcgtccag atgcaacgac
     8581 gcggtcactg atcgacaaga ctgcaccacg gaaacagccc catgatgctt atgttccaac
     8641 gtacgagaac cattcacggg ggggacctct atgtctttct tctttcgtca agcgagacgt
     8701 ggggttctgg gttcgtagaa ggtgccgtcg cggagcatcg cgaacagcac gctgatccgc
     8761 tgtcgggcga ggcgaaagag gggcctgggt atgggatttt ccgcggtcgt agtaggtgcg
     8821 gaaggcggga tcgtgcaggg cggcgaacgc ggacaggaac tatgcgcgct tgagttgccg
     8881 gttgccgatt ctgggcgtgc gttcgccgtg gatcnaggtt cccgacgacc ttgttgtcgg
     8941 ggcgaggccg gcgtaagagg ccaggttagc ggtgttgggg aacctgctgc cgccgccgac
     9001 ggtgaccagc aaggtggcgg cggtcctgac cgcgaccccc ggcatcgagg tcaggaccgg
     9061 gaaaagaggg tgagtctcca gcgactgccc gatctgcgct tccagagctc gtcgccgttc
     9121 gtggacggcc gcgaacgatc gggccagcga cgggatcaca acatcgaggg tgccggtgcc
     9181 cgggaccacg acggtctgct cgtcgagcgt gtcgaagacc tcgtcttcca accgctgggc
     9241 catgcgcgga accttgggcc ggatcacctc aaccagcttg cagcgcccgg ctttccgcag
     9301 ggcggccggg aagccgtagc gttcccgcag ccaggtcacg gcctgatggc ccagacgcgg
     9361 cccgaggacg cgctccaggc tgcggtggaa ctgggtgagc aggccgcgta tccggttgga
     9421 ggtacgggtg gcctcggccg ccaggtcctg gtcgaagtcc accagcacgg tcagttcggc
     9481 ggtgatctcg tcggtcagtt ccaacgagcg cagggtgtgc ggcatcgtcc gggcggcgtc
     9541 cgcgaccact gcggcgtcct tcgcgtcggt cttcacctcg cccgggtaga gatcggcgat
     9601 ccgccgcatc gccaggtcgg gcaattaggc gaccttggcc cgcgtcccgg gcgaccgtca
     9661 ggggcagggc gccgatggag gcgggctcgt tcacgatcac caggacggtc ccgaccttcg
     9721 cggccagctt gccgaagacc gcccgcaact tgggctcgct gttaggcagc tgtttgtcga
     9781 agaccttctt gccggccggc gtgagcccgt gcccgtgatg ggcgttcttg ccgacgtcca
     9841 ggccacggac gacgcccacg tcgtcgatgt cgtacaagcc gtcctcccga acgggattca
     9901 ggaggtgctg gccagggctt cggcatcgtg cgcgcatcca cgttatgtag gcctgccgcc
     9961 cgcgaacggc cgggcatggt gcccggccag gcggtagtcg gacctctcat cagcgtctcc
    10021 aacggcgcct ctcgggcccg gtggccccct cggtcatccc tttgacaggg ggaacagcca
    10081 cgccgggcct ggaggccagc agtcctcttg caggaccgcg aaaaacataa cgggaattcc
    10141 cggtgccatg aaacctgctt taccgggatg aacggtacat ccgaggacga cagagaggaa
    10201 cggattcccg tgtcacacct gacgggtgga gatcgacctg agggagcgct cgccacgacg
    10261 tggccgagtc tcctcgaagc gtgggcggcc gacacacctg acgccatcgc gcttgtcact
    10321 gcggacacgg cactcacgta cgcgcagttc aatgcccgtg cgaaccggct tgcccgttgg
    10381 ctgaaacacc tcggcgccgg accggagcgg tcggtcgggc tggtgctggg caggtccgca
    10441 gacttcttcc tgtgcgcgac tgccgtgctc aagtgcgggg cggcgtacct tccgctggat
    10501 ccgagctacc ccatggagcg gctgtccttc atgacccggg acgcggcacc cgttgcgctg
    10561 gtgacgacat cggacgtccc gggcgaactc ctggaccagc tgtccacccg acgcctcgtg
    10621 tcgctggacg atgaggtagc cgaggacgca ttgcgccgtc tgccggacca cgacatggag
    10681 gacggggaac gcctggagcc actgcgccct gcgagtcccg cctacatcat ctacacctcc
    10741 gggtccacgg ggatcccaaa gggagtcgtc gtcacccacc agggcgtcgc gagcctgatc
    10801 gcgacccagc gtcgtcgcct cgccgtcacc ggcgtctcac gcgtgctcgc cttctcgtcc
    10861 ccgagtttcg acgccagttt ctgggagatg tcgatggcgc tactcaccgg agccgcgctc
    10921 gtggtcggca ggccgggacg gctgctgcct gacaccgaac tggccgcgct gatcgcggac
    10981 cagggagtta cccatctcac tctcccgccc tcagtcgcgg gttcgctgga tcccggcatg
    11041 ttgcctccgg gtgtgacgct ggtcgtcgcg ggcgaagcat gcccggcagc tctcgtacag
    11101 cgctggcgcc cgcaccggac gatggtgaac gcctacggcc ctaccgagtc caccgtctgt
    11161 gccaccatga gcgatccgct ggccgacgac atggcgccgc cggtcggccg ggcagtggac
    11221 ggcacccgga tccatgtcct cgacgatcgc ctcgcacctg ttgtgtcggg agcggttggc
    11281 gagatcttca tcgcggggca cagcctggcc cgcgggtacc tcaagcggcc gggtctgacc
    11341 gctcagcggt tcgtggcgga ccccttcggc ccggccggca gccgtatgta ccgcagcggt
    11401 gacctcggcc gctggacccg ttcaggagag ctggagttcg tcggcagggc ggacgaccag
    11461 gtcaaggtac gcggcttccg tatcgagccg ggtgagatcg aatccgtcct cgccgggtgc
    11521 cgcggggtcc ggcaagccgc cgtcgtcgtg cgcgaggacc ggccgggaga gccgtacctc
    11581 gccgcctacg tcgtacccga gaacgaggcc gccgacgaga cggccgagga agaactggac
    11641 ggtcgactcg ccgcctggcg acggctttac gacgatctgt acgaccgggc agacaccccc
    11701 gacttcggcg aggacttctc tggctgggtg agcagttacg gtgggcggcc gatcgagggg
    11761 atgcgagagt ggcgtgcgca gaccgtgcag cagatccgcg aactggctcc gcgccgtgta
    11821 ctggagatcg gctgcggttc cggtctgctg ctctcgcagc tggcgggcga ctgcgagagc
    11881 tactggggca ccgacatctc tggggctctg atcgagcggc tgcgcgggca ggtcgctgag
    11941 cgccctggcc tcgcagaccg ggtcgtcctg caccggctct ccgcccatga gctggggggt
    12001 ctgccccgca gtggcttcga caccgtcgtg ctcaactccg ttatccagta ctttccttcg
    12061 ggcgactacc tgttcgacgt actgcgtgag gtgtctgggc tccttgcacc cgggggggcg
    12121 gtgttcctcg gtgacgtccg caaccttcgt ttgttgcgca ccttccacac tggggggctg
    12181 ctggcgtcgg cctcgcccgc cgacattccg gagacggtgt gcgcggctat cgaccgggcc
    12241 atggcacagg agagggaact gctcgtggac ccggagttct tcgcgacggt cgtcggcgcg
    12301 ctgcctggca tgacgctgga gtcgtgcacg ctcaaacggg gcggttatga caacgaactc
    12361 agccgctatc gctacgaggt ggtgctgcgc aagcacgccg ggcccgcgga cgacccgggg
    12421 ccggtcgtgc ggctgccgtg ggacggcggg acggcgagcc tggccggcgt cgccgattgg
    12481 ctgcgccgtg ggaaaccaga gcgggtgtgc gtcaccggaa taccgaacgg ccgggtggcc
    12541 ggcgagcatg ccgcgacact cgcgctgttc gaccggcgcc ccctgcccga ggtgttgtcc
    12601 ctggggcagg ttccggctgg tgtggcaccg gaggacctgc gccagctggg cgcggaactg
    12661 ggctaccggg tcgactgcgc atggtcgtcc gagaacgacg ccttgatcga cgcctccttc
    12721 accctcgccg gaacgctcgt gccgcgtccc gccccccgga ccgacgctaa gccggacgac
    12781 ttctccccgg ccaggttcac caacaggccg gcgttcgccc gccctgactc ccggacgatg
    12841 gcctcacttc ccgggcaggt ggcggcgcag ctgccagcct tcatggtccc cgaggtcttc
    12901 gtcccgctcg acaggctgcc ggtcacggtg aatggaaaac tcgaccgcgc cgccctgccc
    12961 cggccgcagc gcgccgcccc tgccgcggga cgtccgccca agaccgcccg cgaggaggta
    13021 ctcgcggcga tcttcgccga cgtactcgcg accgccgacg tcacagccga cagcgacttc
    13081 ttcgccaccg gcggcaactc cctgctggcc acccgcctcg ccgccgaggt ccggcaccgc
    13141 ctggacaccg agatgccgct gtcgtggctg ttcgagtcgc ccaccgtcga ggcgctcgcc
    13201 gcccgcttcg acgcagagga cgaggctagg ccggtgcccg tgccgggcga gtacgcctcc
    13261 ggcagcacgg caccgttgtc ggcccaacaa ctgcagatgt gggacgagta ccgccaaagc
    13321 ctgcacaggg acatgttcaa tgtaccgctg tcgctgcggc tgactggtgc cgtcgacgct
    13381 gaggcactgc gcgccgcctt ggccgacgtc gtcacccggc acgttccgct gcgcacgctc
    13441 gtccgggacg acggtagcgg tccgtgcgcg gtgatcacgg aagccaccgc ggacgacatc
    13501 ccctggacgc agaccaggac gacacccaag cggctgcccg aggatctcgc gcacgccgcc
    13561 cgccgccact tcgacctcga aaccgagatc ccgctgcggg ccgcacactt cacgctcggc
    13621 ccgaacgagt ccgtactgct gctggtcatg catcacatcg ccgccgacgg ctggtccttc
    13681 ggccccctgc aggaggacct ggtgcgcgcc taccgctcca ggaccgaggg acacgcacca
    13741 cagtgggagc cgctgtccct cggctacctc gattacgtcg cctggcagcg ccgactcctc
    13801 ggctccccgg acgacccgag cgatgtcgcg ctgcgccagg ccgagtactg gaggaagaca
    13861 ctgcacggtg ccgacgacag gccggtcctg gagaccgaca gcccggcgcc gtcccggcag
    13921 gacttcgccg gtaggtccct cgaccttcca ctcgaagtcg gcggccaccg ggtgctgaca
    13981 gccgcggctc gtgaacacgg tgtcaccgtc ttcatgatcc tgcacgcggc gctcgtcgca
    14041 atgctcgccc gaaagggggc gggaggagac atcaccgtca cgaccgcggt ggctggccgg
    14101 accgacaccc agttcgaacc gctcgtgggc ctcttcgcca acaccctggc cctgcgcatc
    14161 gacacgtcgg gcaaccccac tttccgtgaa cttctgtacc gggtccgcgt gaccgatctc
    14221 gctgcctacg cccatcagga cctgctcttc gagcacctgg ccgacatgcc atcgccgcag
    14281 gtgtcactcg tcctgcgcac ggtcgcggcc ccgccctccg acctgcctgg cctcactctc
    14341 gctcccggcc cacgacccgc gagcgaatcc gcccgctatc cggtgctgtg gaccgtggag
    14401 cacctggcct ccaccgccga cagcgggacg ctgcgcagcc acatccagta ccagagcggg
    14461 ctgctgcgcg acgacacggt cgcccggatc gcccagcggt acgaagtcgt gctgtccctg
    14521 ttgctgaagg atccggacct ccgcgtccaa gacctcccac cgcagtgaat cccagggcca
    14581 gcccgtccga tcccatcctc tgtgaggtcc actcgatgtc cacgctgccg ccggggcgaa
    14641 gccgtaccac ggccccgccc gccgggcccc aggccagccc cgagttcacc cccgacctgt
    14701 ggggacggct cttcgaagcc cgtgtcgacg ccgaccccga atccaccgcg atcaactccg
    14761 cgagcgatcg gctgagttac gccgaactga actggcgggc caaccgcctg gccagactgc
    14821 tcgtcgcaca tggcgccggc ccggagagcc tggtcggtat cgccctgccg cgctcgaccg
    14881 acttcgtggt ggccgtggcg gccgtactga agtcgggcgc cgcctacttc ccgctggacc
    14941 cggaatatcc tccgcaacgg ctggcgttca tgctcgccga cgccgctccc ctgctggttc
    15001 tgaccagaag cgacatcgag cccgagctgc cggccgaggc ggcctcccgc acggtggtcc
    15061 tggacgaccc ggccgtcgta cggaccctga ccgaccgctc cgcagcggac gtgaccgacg
    15121 acgaacgcgt cgccccgctc cggacctggc atccggccta tgtcatctac acctcgggtt
    15181 ccaccggtac tcccaaaggg gtggtcctca cccaccacgg catcgctggc ctggtgggca
    15241 gccatgcgcg agacctgggg atcggggcgt ccagtcggct cctgctcttc tcttcgccga
    15301 gcttcgacgg cgccttctgg gacgtgtcga tggctctact cactggcgcc acgctggtgg
    15361 tcgcgccacg tgaacggctc ctgcccggac cggagttcag cgcactcgtt gccgaggagg
    15421 gcatcaccca cttcgccctg tcggcctcca cactctccgc cctgccggac ggcgctctgc
    15481 ccgccggggc caccgtcgtc aacgtgggcg aggcatgcaa cggcgagctg gtacgccgct
    15541 ggtcgccggg tcggctgatg gtgaacgcgt acgggccgac cgaatcgacc gtctccgcga
    15601 cgatgagcgg accgctggcc gcggaaggca tgccgcccat cggccgtccg ctctcggaca
    15661 cccgcgtaca cgtgctcgac gagcggctcc ggccggtacc gccgggggcg gtcggagaga
    15721 tccacatcgc cggagcgggg ctggcccgcg ggtacctggg gcgacccgcg ctgactgctg
    15781 agcggttcgt ggccgatccc ttcggggcgc cgggcaagcg gatgtaccgg acaggtgacc
    15841 tggcgcgggt gcgtgacgat gggcagctgg agttcgtggg cagggtcgac gaccaggcga
    15901 agattcgggg tttccgcgtg gagcccggcg aggtcgaagc catgctgcgc gaccatcccg
    15961 aggtcgcgca ggctgcggtg ctggtccggg aggacactcc gggagaccaa cggctcgtcg
    16021 cctatgtcgt gccggaccac ccggccgttc gtcaggncga cggcaccgcc tcggagcacg
    16081 tcggagagtg gcaacggctc tacgacgagg tctacagcac ggtaggagcg ctncctctgg
    16141 gtgaggactt cagcggatgg aacagctcct acgacggcga tcccattccc ctgccgcaga
    16201 tgcgagcctg gcgggatgcc acggtcgaca gcatccgtgc cctgcgaccg cgccgagtac
    16261 tggagatcgg cgtgggcacc gggctgctgc tgtcccacct cgccggtgac tgcgaggcgt
    16321 actgggccac cgacttctcc accgaggtga tcgaggcact cggcaagaaa gtggacggcg
    16381 acccggtcgt gcgcgagacg gtccanctgc ggcccggccc cgcacacaac ctccccggcc
    16441 tcccagaagg atacttcgac accgttgtcc tcaactcggt gatccagtac tttccgtcgg
    16501 ccgactacct ggtgagcgtc ctgcgcgagg cggtacgcct cgtggcgccg ggcggccggg
    16561 tgttcgtcgg cgacgtccgg cacttgcgtc tgctgcgccc gctgcgcagc gccgtccggc
    16621 tgcgctccgc catcgggcgg gaagtctcgg cntccgacgt ccgtgcggcg gtcgaccaag
    16681 acttgatgga cgagaaggag ttgctcctcg atcccgcatt cttcacggtc gtatcccggt
    16741 ggattccgca gatccgcggg gtgcgcacag cggtgaagcg cggcacgcac cacaacgaac
    16801 tgacccgtta ccggtacgac gcggtgctca tcaaggagcc ggtgaaaacc ggtactgtcg
    16861 cgccggacgc gcggaccctg acctggggca cggatgtcgg tggactgcaa ccgttgtccg
    16921 gcctgttggc ccgcatccgt acgccactgc tgctgcgcgg cgtaccgaac agccggattc
    16981 tcgctgaggt ctcggctgcg gcggcgctgg ccacggcccc gtcgctcgac gaaccgtcgc
    17041 ggttgctgcg cgaaccggcg accgggatcg accccgagga actgcacgcc ctgggcgaag
    17101 gtgctggcta cgaggtccac ctcacatggt cagcgcagga ccccacgcga gtggacgcac
    17161 ggttcacacc cgcgggcggt gaaccggacg ccgtcccgcc ggcggactcc gccgacagtg
    17221 tcaggacgtc ccccggtgac cacgccaatc agccgaccac gcaccggacc ggcatggctc
    17281 tgatgagcaa gctccccggt tatctggccg ccaggctccc cgcgtacctg cggcctagcg
    17341 ccctggtacg tgtcgagtcg ctccccctca ccgtcaacgg caagctcgac cgcgcggcgc
    17401 tgccccctcc cctgctgttc ccgcaggccg acgggcaggc accccgcact ccgcgcgagg
    17461 agatcctcac ccatctcttc gccgatgtgc tcggcctgcc tggggtgccg agggacgccg
    17521 acttcttcgc cctgggcggc aactcgctgc tggccacgcg cctcgtcggc cgcatcgcga
    17581 aacacctcga agtagatgtt ccgatcgcct gggtcttcga gacaccgacc gtcgagggcc
    17641 tggccgggcg taccgcgccg acgagcaggt tccgccgacg gctggtctgc cgcgacgagc
    17701 accacacggc ggtgccgctc tcgcacagcc agtacggcat gtggttcatc aaccagctcg
    17761 gcggacccgc gagccggatc tacaacgtgc cgtactgcct gcggctcacg ggccgggtgg
    17821 actccgcggc gttgcggatc gcactcgacg acgtcgtggc tcgtcatgaa cctctgcgca
    17881 ctgtcttccc cgacgacggt gacggccccc gccagcgggt cctcgccccc gaggacgccg
    17941 tggtggtcct ccatgagacc gataccttcg aagaccgtct cgccggcgaa ctgtcacggg
    18001 ccgcggcgga acccttcgag ctcaggacgg accttcccct acgtgcacgc ctgttccggc
    18061 acggccagga ccggtccacg ctgctgctcc tgatgcacca catcaccgtg gacgcctggt
    18121 cactggcccc cctgaccgct gacctgacgc gtgcctaccg tgctcggctc gggcagcggg
    18181 ccccgcagtg gcagccgctg ccggtccact atcgcgacta cgccgtatgg cacaacgccc
    18241 aggtagccgg gacccaggac cgcagcagcg gcttcgggcg cgggctcgcc ttctgggagc
    18301 ggatgctgcg aggtcttccg gtcgagatgc aactgccggt cgaccggcgc cggccagcca
    18361 gacccaccta ccgtggcggc accgtccata cccgcatcga agcctccctc caccaagaac
    18421 tgctcaactg cgcgcgggag acgggcgcga cgcccttcat ggtgctgcac gctgcgctcg
    18481 cggcactgct gacccggctg ggcggcggca ccgacattgt cgtcggcacc gctgccgcag
    18541 cacgcacgga ccccgcgctg gacgacctcg tcgggctgtt cgccaacagt gtcgtccttc
    18601 gcgtcgacac ttcgggcgac ccgacattcc gcactctgct tgcccgtgcc cgtgccgtgg
    18661 acctcgacgc cttcacccac caggaggtcc ccttcgacca ggtggtggat ctcctcaacc
    18721 cggcacgcca cccggcacgt cacccgctct accagacggc cctcgtcctc cacacaccgc
    18781 ccggcgacgg ccatcgagcc cacctcgtca ccctcacccc cgaaccgccc ccggacaccg
    18841 gaacggcccg cttcgatctg atgttcaact gggacgagaa ccgggacagc gccggccttg
    18901 cccagggcct caccggccgc accgagtaca gctcggatct cttctcccag gagacggtcg
    18961 aactgctcct ggagcggtat gtcctgctgc tgtccgcagt ggtccgcgag ccggacacac
    19021 gccttcacac cctgaacatc ctcaccgagc cggaacggca ggccttctca cgacggccgt
    19081 agccctccga ctccgtatca ccgggagaaa tcctccatgc cttcaccctt cgacgaccac
    19141 cacgggcagt tctatgtact ccgcaacgaa gaaggtcagt tctcactctg gccggatttc
    19201 gctgacatcc cctccgggtg gcattccgtg agcgggcccg tctcccgcga cagcgccctt
    19261 ggctacatcg aggggcagtg gacggacatg cgcccgangt ccgcccgtgc atgaccctgc
    19321 caagtcggca cccaggcacg accctgccca cttcctcagt ttcgaccacg cggtatgacg
    19381 tgaggcgccg ccatgatgcc gcacgagccc gcggcattgg aaaggaaacg gcaccatgga
    19441 atctacgccc gaccaagccc accctacgaa ctcaccgttg gagccctatc acatctaccc
    19501 ggaggccagg tcctgtccgg tggcgaaggt cagcctgtgg aacggcacac cagcgcacgt
    19561 gttctccggg catgacgagg tgcggaccgt gctacaagac aggcggttca gctcagactc
    19621 gcgacggccc aacttcaccg aactcactcc gacgctccaa tcgcaggccg cgcaaccgcc
    19681 gtttgtacgc accgacaacc ctgatcatcg gcgcctacgg ggcaccgtcg cccgtgagtt
    19741 cctgcccaag cgcatcgagc tgctgcgccc cgcgatccgc gagatcgtcc agggtgtgct
    19801 cgacaggctc gccgagaccg cacctcccca ggacatgttc gaggccttcg ccgtccccgt
    19861 ggcgtccgcg accgtcttcc ggctgctggg gattccggcc gaggaccgcg cattgctcac
    19921 ccgatgcgtc aagggcgtgg tttcggcggt ggggagcgag gacgaaggtg ctgaggtgtt
    19981 caggatactc ggcgagtaca tcggcggcct cgtccaagac tcctccgcac tgcccgagga
    20041 cagcatgatc cggcgtttgg tggagggccc gtactccgcg aaggagctca ccttccacga
    20101 ggccatcggc gtgatcctca tgctcatcgt cggcggttac gacacgacgg cgagcaccat
    20161 ttcgctgtcc ttggtgagtt atgcgctgca cccggagaag ttctccttcg tccacgaacg
    20221 gccggagcgg atccccatgc tcgtcgagga gttgctgcgc tatcacactg tcgcgcagct
    20281 cgggctgggc aggatcgcca ccgctgacgt cgaggtgggc agtgtcacgg tgcgggccgg
    20341 cgagatggtg gtggccgcgc tctcgctggc caatcgagac aagagtgtct ttcctaaccc
    20401 ggacaaactc gacttcgacc gcccgtccgt tcctcatgtc ggcttcggct acggaccaca
    20461 ccagtgcgtc ggccaggcgc tggcccgtgt cgaacttcaa gaggccattc ctgccgtgat
    20521 ccgacgactg cccggcctgc ggctcgcctg cactctggaa gaccttccat tccggcacga
    20581 catgtccacc tacggcgtcc atgagctgcc tatgacctgg tga
//
