LOCUS       BGC0000445             64650 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Micromonospora sp. ML1 thiocoraline gene cluster.
ACCESSION   BGC0000445
VERSION     BGC0000445
KEYWORDS    .
SOURCE      Micromonospora sp. ML1
  ORGANISM  Micromonospora sp. ML1
            Bacteria; Actinobacteria; Micromonosporales; Micromonosporaceae;
            Micromonospora; unclassified Micromonospora.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 19:25:32
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 64650
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..64650
                     /country="Mozambique:ocean coast"
                     /db_xref="taxon:349725"
                     /host="soft coral"
                     /mol_type="genomic DNA"
                     /organism="Micromonospora sp. ML1"
     subregion       1..64650
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="NRP"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..64650
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             <1..538
                     /codon_start=2
                     /db_xref="GOA:Q333W7"
                     /db_xref="InterPro:IPR012337"
                     /db_xref="UniProtKB/TrEMBL:Q333W7"
                     /note="ORF1"
                     /product="putative transposase"
                     /protein_id="CAJ34355.1"
                     /transl_table=11
                     /translation="IPSREWQPHSCGPGAKGPREYLWAWITTATSAGEHRWLLMRRNRS
                     TGELAFYLCWSPRPAPLHTLVTVAGSRWSIEELFQSGKGQVGLDHYQVRGWTGWHRHVT
                     LAMLALAVLTILAARQPDPDPEIIALTVAEIRGLLNAFVLAVTLPPAHTLHWSTWRRTS
                     QARARRAHYQRRQAK"
     CDS             complement(990..1130)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q333W6"
                     /note="ORF2"
                     /product="hypothetical protein"
                     /protein_id="CAJ34356.1"
                     /transl_table=11
                     /translation="MRSCGRRLARVTRIGNPRQGLQAPRGQQSVSRAGRGMLTGYVDQR
                     R"
     gene            1517..2134
                     /gene="tioA"
     CDS             1517..2134
                     /codon_start=1
                     /db_xref="GOA:Q333W5"
                     /db_xref="InterPro:IPR001867"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="InterPro:IPR016032"
                     /db_xref="UniProtKB/TrEMBL:Q333W5"
                     /gene="tioA"
                     /product="OmpR family regulator"
                     /protein_id="CAJ34357.1"
                     /transl_table=11
                     /translation="MSVSGSRRSEGSYRRSGGCAQGRSPRPAREDVKFVRWPAERHLRD
                     LCRQERIPCLLVVEGGAEPPVCSDPREDWVRTPISPSDLDARVTALRQRSHDRRTPVLD
                     PAGTLSFRTASVVMSSTHLELMDLFVERFGQVVYRWELMTILTKRDSTSTRNALDLHIM
                     RMRKRIAPLDLDIVTAWGRGYALEEKSSWAAVASKPAAVDHC"
     gene            complement(2151..2822)
                     /gene="tioB"
     CDS             complement(2151..2822)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q333W4"
                     /gene="tioB"
                     /gene_functions="biosynthetic (rule-based-clusters) other:
                     LmbU"
                     /gene_kind="biosynthetic"
                     /product="putative regulator"
                     /protein_id="CAJ34358.1"
                     /sec_met_domain="LmbU (E-value: 3.3e-85, bitscore: 276.1,
                     seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAGSRSSRNAVAALRVVPAATAGVPKQRPAEPAQVMLTRVGLRL
                     PERMSFEHWERTGAQLSGIVDSSSWCLGDWLVYGKEQYADRYRHVVQAVGLDYQTLRNY
                     AWVAGRFPLARRRSGLSFQHHAEVAAMSPDDQDRWLDEAETQMWSVKQLRAAIKATRSD
                     RTTETIKTALMPRIPIPDRRLTRWRQAAHQSSVELDQWIVSTLDRAAAETLDKTTHDET
                     E"
     gene            complement(2967..3791)
                     /gene="tioC"
     CDS             complement(2967..3791)
                     /codon_start=1
                     /db_xref="GOA:Q333W3"
                     /db_xref="InterPro:IPR000412"
                     /db_xref="InterPro:IPR013525"
                     /db_xref="UniProtKB/TrEMBL:Q333W3"
                     /function="involved in thiocoraline resistance"
                     /gene="tioC"
                     /gene_functions="transport (smcogs) SMCOG1065:ABC-2 type
                     transporter (Score: 267.1; E-value: 1.9e-81)"
                     /gene_kind="transport"
                     /product="ABC transporter (permease subunit)"
                     /protein_id="CAJ34359.1"
                     /transl_table=11
                     /translation="MVSTSLKPRLDAAAAQQQTGLSWWLSDAWQMALRNLRHLTRSPEL
                     VMFSLVQPVMFILLFAYVFGGAINVEGGNYPQFLLPGILVQMVLFGSVAGTTIGISTDM
                     DRGLMDRFRSMPMSRSAVLVGRTLSEILRNVVSMLVVVLMGLLIGFRFQGGVLSALGGL
                     ALLLLFGYALTWVGAMIGLSVPNPEAAQSAGLIWIFPFSLISSAFVPTESMPTWLRVYA
                     DASPMTATVNALRDLFNGNPPGLDVLLTVAWSVLLITIFAPLATRKYSLRSR"
     gene            complement(3791..4777)
                     /gene="tioD"
     CDS             complement(3791..4777)
                     /codon_start=1
                     /db_xref="GOA:Q333W2"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR005894"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="UniProtKB/TrEMBL:Q333W2"
                     /function="involved in thiocoraline resistance"
                     /gene="tioD"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 185; E-value:
                     2.9e-56)"
                     /gene_kind="transport"
                     /product="ABC transporter (ATPase subunit)"
                     /protein_id="CAJ34360.1"
                     /transl_table=11
                     /translation="MPAAIEVAGLCKRFGSVTALDHLELTVPEGKVHGLLGPNGAGKTT
                     TVRVLTTLLRPDEGKAEIFGFDVRRNALQVRSIIGLTGQYTTVDDMLTGRENLHMVGKL
                     FRMSTPDIKVRATELLERFDLTEAAGRQAKTYSGGMRRRLDIAATLMSRPQLIFLDEPT
                     AALDPRSRMDVWRIVNELVEEGTTVLLTTQYLEEADHLADSLSVIDSGKVIASGAPDEL
                     KAEVGQAWADVTLIDAAAVEKTTQILRERLGTEPVGDPEGMQVHAPLPEGMTLNELLNP
                     LRDSGIAIADVAVRRPTLDDVFLALTGHTATARASEDVNSKKKGGKR"
     gene            4904..5614
                     /gene="tioE"
     CDS             4904..5614
                     /codon_start=1
                     /db_xref="GOA:Q333W1"
                     /db_xref="InterPro:IPR000551"
                     /db_xref="InterPro:IPR009061"
                     /db_xref="UniProtKB/TrEMBL:Q333W1"
                     /function="putative ABC transporter regulator"
                     /gene="tioE"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1171:transcriptional regulator, MerR family (Score:
                     55.8; E-value: 1.3e-16)"
                     /gene_kind="regulatory"
                     /product="MerR family regulator"
                     /protein_id="CAJ34361.1"
                     /transl_table=11
                     /translation="MYFRPADLAHEHGLSPQSVRNYERDGLIPPARRTESGYRRYTEKH
                     AAALRAYRALIPAHGYAESGAIMRDITAGRLNEALTTIDRSHAELLRDRGTLDAVAEVL
                     THLTGRSTGTWRAPKSIQPYSIGELAHRLGVNVATIRKWETSGVLAPVRRPETGHRMYD
                     ASDVRDAELAHFLRRGRYPLELIATVVQQVRAAGDTQALAAALADWRQRVTTRGLAMLN
                     AAAQLASYLAMEEN"
     gene            complement(5698..6426)
                     /gene="tioF"
     CDS             complement(5698..6426)
                     /codon_start=1
                     /db_xref="GOA:Q333W0"
                     /db_xref="InterPro:IPR004981"
                     /db_xref="UniProtKB/TrEMBL:Q333W0"
                     /function="involved in 3-hydroxy-quinaldate biosynthesis"
                     /gene="tioF"
                     /product="Tryptophan 2,3-dioxygenase"
                     /protein_id="CAJ34362.1"
                     /transl_table=11
                     /translation="MTTLTYADYLQVDTLLSLQETRAPDTASRSVVLAEHFFIVTHQAC
                     ELWLKQVTYDLDAAADAMTPPYGPEDEELALEFLQRTAELLRVLHEQVVALERLPLRHF
                     AEFRPFLDGASGAQSAQFRLLARLLGGERQEGRLYRAFERLTEHNGISVAEVCARGPGA
                     GVLNRIADSLLDVANGYWRWKMTHLALVSKMVGNRNGTGGSTGVDYLARRITLPFAQLR
                     QLRAQVHDALVWEQPTAHTQ"
     gene            complement(6423..7688)
                     /gene="tioG"
     CDS             complement(6423..7688)
                     /NRPS_PKS="Domain: Aminotran_1_2 (41-378). E-value:
                     2.3e-54. Score: 176.7. Matches aSDomain:
                     nrpspksdomains_tioG_Aminotran_1_2.1"
                     /codon_start=1
                     /db_xref="GOA:Q333V9"
                     /db_xref="InterPro:IPR001176"
                     /db_xref="InterPro:IPR004838"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="UniProtKB/TrEMBL:Q333V9"
                     /function="involved in 3-hydroxy-quinaldate biosynthesis"
                     /gene="tioG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 218.5; E-value:
                     2.4e-66)"
                     /gene_kind="biosynthetic-additional"
                     /product="kynurenine aminotransferase"
                     /protein_id="CAJ34363.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.7e-07,
                     bitscore: 21.4, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLPSPYPNLLDGPSVASTIPSSELHRVFRDAGERERISGVPVTK
                     LHVGEPYFTPPPEVAQALAEAVTAGRTDYTAVEGLLELRERLVEKLADQNGVDTDVSRL
                     FVTPGSCQGLAALMQAVAEPDAEILLPELHWPIHLQQVLLAGLRPVFYPLGRDYRTDPE
                     SVLAASTANTRVLLINSPANPTGAVLDTATLSTLIDMARARGWQVISDEAYEHFVFDDE
                     HVSTASLEWDVPVSERIVHSSYSFSKSLAMTGYRLGYVSTANDRTAHAFRIVQEANLIA
                     MSTPVQYAGLEALRLGHVVRENRAMVLSNRDAVLPAVRDAGLLPELPAGGWYAVLDVAP
                     TGLTAEEFATGLLETRNVAVVPGTGFALMPRLDARGRVITVEPAPWSRHLIRIAMCVAP
                     SVLRSGVRELLEFARERPGTAR"
     aSDomain        complement(6555..7565)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioG_Aminotran_1_2.1"
                     /evalue="2.30E-54"
                     /label="tioG_Aminotran_1_2.1"
                     /locus_tag="tioG"
                     /protein_end="378"
                     /protein_start="41"
                     /score="176.7"
                     /tool="antismash"
                     /translation="PVTKLHVGEPYFTPPPEVAQALAEAVTAGRTDYTAVEGLLELRER
                     LVEKLADQNGVDTDVSRLFVTPGSCQGLAALMQAVAEPDAEILLPELHWPIHLQQVLLA
                     GLRPVFYPLGRDYRTDPESVLAASTANTRVLLINSPANPTGAVLDTATLSTLIDMARAR
                     GWQVISDEAYEHFVFDDEHVSTASLEWDVPVSERIVHSSYSFSKSLAMTGYRLGYVSTA
                     NDRTAHAFRIVQEANLIAMSTPVQYAGLEALRLGHVVRENRAMVLSNRDAVLPAVRDAG
                     LLPELPAGGWYAVLDVAPTGLTAEEFATGLLETRNVAVVPGTGFALMPRLDARGRV"
     gene            complement(7730..8524)
                     /gene="tioH"
     CDS             complement(7730..8524)
                     /NRPS_PKS="Domain: PKS_KR (22-184). E-value: 7.2e-19.
                     Score: 60.2. Matches aSDomain:
                     nrpspksdomains_tioH_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GOA:Q333V8"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="UniProtKB/TrEMBL:Q333V8"
                     /function="involved in 3-hydroxy-quinaldate biosynthesis"
                     /gene="tioH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     226.3; E-value: 7e-69)"
                     /gene_kind="biosynthetic-additional"
                     /product="NAD or NADP oxidoreductase"
                     /protein_id="CAJ34364.1"
                     /sec_met_domain="adh_short (E-value: 6.2e-38, bitscore:
                     121.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPTEAEAWPAVAERGDGLAGRTVIVTGAGTGLGRAIGERLLARD
                     ANVVAVGRREAALRELTGDGGGQVATVAADITEPGAAEHVVAAATTRFGTVHGLVNNAG
                     LARFATLDTASDEDFDRLLATNVRAPAALIRAALPHLREHRGAVVNVSSVGAVLAMPGR
                     SFYGASKAALNSLTRSLARELAPDVRVNAVLPGPVDTPMWDDMGLDSVKSALLRSSLLA
                     ATPLGRFGQPAEIAGWVCGLLDPEFSGWITGALIPVDGGRTS"
     aSDomain        complement(7973..8458)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioH_PKS_KR.1"
                     /evalue="7.20E-19"
                     /label="tioH_PKS_KR.1"
                     /locus_tag="tioH"
                     /protein_end="184"
                     /protein_start="22"
                     /score="60.2"
                     /tool="antismash"
                     /translation="TVIVTGAGTGLGRAIGERLLARDANVVAVGRREAALRELTGDGGG
                     QVATVAADITEPGAAEHVVAAATTRFGTVHGLVNNAGLARFATLDTASDEDFDRLLATN
                     VRAPAALIRAALPHLREHRGAVVNVSSVGAVLAMPGRSFYGASKAALNSLTRSLAREL"
     CDS_motif       complement(8363..8458)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioH_0001"
                     /evalue="2.80E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="tioH"
                     /protein_end="54"
                     /protein_start="22"
                     /score="13.6"
                     /tool="antismash"
                     /translation="TVIVTGAGTGLGRAIGERLLARDANVVAVGRR"
     gene            8791..10005
                     /gene="tioI"
     CDS             8791..10005
                     /codon_start=1
                     /db_xref="GOA:Q333V7"
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002397"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="UniProtKB/TrEMBL:Q333V7"
                     /function="involved in 3-hydroxy-quinaldate biosynthesis"
                     /gene="tioI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 379.9; E-value:
                     2.2e-115)"
                     /gene_kind="biosynthetic-additional"
                     /product="quinaldate 3-hydroxylase"
                     /protein_id="CAJ34365.1"
                     /sec_met_domain="p450 (E-value: 1.7e-16, bitscore: 51.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPTASTSALDLTDPTTFVRHDTHVFWAEVRDHNPVYWYQGRED
                     RPGFWVVSRYVDVVASYTDAARLSSARGTVLDVLLRGEDSAGGRMLAVTDRPRHRELRN
                     VMLRAFSPRVLGRVVEQVHRRADELIRRVTGTGAFDFATEVAESIPMGTICDLLSIPPA
                     DRPDLLRWNKNALSSDEADANLYAALEARNQILLYFMDLAEQRRASPGDDVISMIATAT
                     VGGEPLSIDDVALNCYSLILGGDESSRMSAICAVKAFADFPDQWRAVRDGDVAIDTAVE
                     EVLRWSTPAMHFARTATTDFELRGQQVRAGDIVTLWNLSANFDEREFDRPYRFEVGRTP
                     NKHLSFGHGPHFCLGAYLGRAELQALLTALVGTVSRIESAGSPRRVYSNFLNGHSSLPV
                     AFTGR"
     gene            complement(10019..11590)
                     /gene="tioJ"
     CDS             complement(10019..11590)
                     /NRPS_PKS="Domain: AMP-binding (27-429). E-value: 5.5e-82.
                     Score: 267.3. Matches aSDomain:
                     nrpspksdomains_tioJ_AMP-binding.1"
                     /codon_start=1
                     /db_xref="GOA:Q333V6"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="UniProtKB/TrEMBL:Q333V6"
                     /function="putative loading module"
                     /gene="tioJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     441.9; E-value: 4.1e-134)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative 3-hydroxy-quinaldate-AMP-Ligase"
                     /protein_id="CAJ34366.1"
                     /sec_met_domain="AMP-binding (E-value: 6.3e-87, bitscore:
                     283.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPWPEELAALYRREGYWQGRPLGDLLTEACARHADKTALVCGERR
                     MTYAELSRASADVAGGLLDVGIEPLDRVVVQLPNVPEFVVVVYALLRIGAIPVMALPGH
                     RKVELTHLCAHSQAVALVVVDQVKGFDHRALAREVRAEVPALKHVVVAGDAEEFTALAD
                     LYRRGRDLPAVDPSEPALFLLSGGTTGLPKLIPRTHDDYAYNMRATADALRFGAEDVYL
                     AVNPIGHNSALGCPGVLGALLVGGTAVLTSSVRPDEVFELLERERVTLTTLVPPVVRLW
                     LDAARKSDVRFPNLMLQVGSSKFDPARAAEVRTSLGAVLTQWFGVGEGLLTYTRLDDPE
                     EVVLATEGRPLAAHDEILVVDTDGRPVPDGAEGELLVRGPYTIRGYYRAEEQNRRSFTP
                     DGYFRTGDMVRRRPDGSIVVVGRIKDIINRGGEKVPAEEIEEHLLAHAAIRDAAVVGVA
                     DPVLGEKTVAFVILRDEPISPAAVKSFLRERGLATYKIPDRVVPIEEFPRTAVGKVDKV
                     TLRTSG"
     aSDomain        complement(10304..11509)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioJ_AMP-binding.1"
                     /evalue="5.50E-82"
                     /label="tioJ_AMP-binding.1"
                     /locus_tag="tioJ"
                     /protein_end="429"
                     /protein_start="27"
                     /score="267.3"
                     /tool="antismash"
                     /translation="EACARHADKTALVCGERRMTYAELSRASADVAGGLLDVGIEPLDR
                     VVVQLPNVPEFVVVVYALLRIGAIPVMALPGHRKVELTHLCAHSQAVALVVVDQVKGFD
                     HRALAREVRAEVPALKHVVVAGDAEEFTALADLYRRGRDLPAVDPSEPALFLLSGGTTG
                     LPKLIPRTHDDYAYNMRATADALRFGAEDVYLAVNPIGHNSALGCPGVLGALLVGGTAV
                     LTSSVRPDEVFELLERERVTLTTLVPPVVRLWLDAARKSDVRFPNLMLQVGSSKFDPAR
                     AAEVRTSLGAVLTQWFGVGEGLLTYTRLDDPEEVVLATEGRPLAAHDEILVVDTDGRPV
                     PDGAEGELLVRGPYTIRGYYRAEEQNRRSFTPDGYFRTGDMVRRRPDGSIVVVGRIKDI
                     INR"
     CDS_motif       complement(10400..10489)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioJ_0001"
                     /evalue="6.20E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="tioJ"
                     /protein_end="397"
                     /protein_start="367"
                     /score="18.6"
                     /tool="antismash"
                     /translation="PDGAEGELLVRGPYTIRGYYRAEEQNRRSF"
     gene            11847..13637
                     /gene="tioK"
     CDS             11847..13637
                     /NRPS_PKS="Domain: AMP-binding (7-404). E-value: 2.3e-101.
                     Score: 331.1. Matches aSDomain:
                     nrpspksdomains_tioK_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (518-586). E-value: 7.2e-19. Score:
                     59.6. Matches aSDomain: nrpspksdomains_tioK_PCP.1"
                     /codon_start=1
                     /db_xref="GOA:Q333V5"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="UniProtKB/TrEMBL:Q333V5"
                     /gene="tioK"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 383;
                     E-value: 3e-116)"
                     /gene_kind="biosynthetic"
                     /product="NRPS protein"
                     /protein_id="CAJ34367.1"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-107, bitscore:
                     350.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-13, bitscore:
                     42.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTVAELFESVVARSGDHVAVIFGDRLVSYAELDARANRLARVLV
                     ERGVGPDTTVAVAMPKCDELMVVLLAVLKAGGAYLPLDPQYPAKRLAYMVQDARPTLLV
                     RMAQVSLELGVPVAELVVDDPDTARETESRPDHQLTDASRNAPLRPDNLMYVIYTSGST
                     GTPKGVAVTHTGVADIVAAQTASIAPRPGDRVLQWASVSFDAAFWDWSAALLSGATLIM
                     APADELLPGQPLRDTLRRYAVTHAVLPPVALSVTEPDDVLVGGTLMSTGDACTRALVAK
                     WAPGRRMYNGYGPTETTVGSTIAGPIAISDEITIGTPWSGNRVYVLDERLRPVPNGRDG
                     ELYLAGNGLARGYLNRPGLTASRFVLDPFGPPGGRMYRSGDRGHRRADGQLVFASRGDD
                     QVKIRGFRVELGEVEARLAAHPAVDVAAVVVVGDLAGARLAAFVSTVAGTGVSAAELSA
                     HSAETLPEHMVPSSVQVLQRLPVTANGKIDRAALRDLAESAAHPDAAASAGPPGEDPTS
                     VESRLCLLVRELLAVPDVRPGDNFFKLGGHSVLATRLAGRLRDEWGITVPIRAVFEAAT
                     LSELALVVQASKASIPNGRP"
     aSDomain        11868..13058
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioK_AMP-binding.1"
                     /evalue="2.30E-101"
                     /label="tioK_AMP-binding.1"
                     /locus_tag="tioK"
                     /protein_end="404"
                     /protein_start="7"
                     /score="331.1"
                     /tool="antismash"
                     /translation="FESVVARSGDHVAVIFGDRLVSYAELDARANRLARVLVERGVGPD
                     TTVAVAMPKCDELMVVLLAVLKAGGAYLPLDPQYPAKRLAYMVQDARPTLLVRMAQVSL
                     ELGVPVAELVVDDPDTARETESRPDHQLTDASRNAPLRPDNLMYVIYTSGSTGTPKGVA
                     VTHTGVADIVAAQTASIAPRPGDRVLQWASVSFDAAFWDWSAALLSGATLIMAPADELL
                     PGQPLRDTLRRYAVTHAVLPPVALSVTEPDDVLVGGTLMSTGDACTRALVAKWAPGRRM
                     YNGYGPTETTVGSTIAGPIAISDEITIGTPWSGNRVYVLDERLRPVPNGRDGELYLAGN
                     GLARGYLNRPGLTASRFVLDPFGPPGGRMYRSGDRGHRRADGQLVFASRGDDQVKIR"
     aSModule        11868..13604
                     /complete
                     /domains="nrpspksdomains_tioK_AMP-binding.1"
                     /domains="nrpspksdomains_tioK_PCP.1"
                     /locus_tags="tioK"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       12054..12095
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioK_0001"
                     /evalue="3.40E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="tioK"
                     /protein_end="83"
                     /protein_start="69"
                     /score="20.0"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       12306..12365
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioK_0002"
                     /evalue="1.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="tioK"
                     /protein_end="173"
                     /protein_start="153"
                     /score="32.7"
                     /tool="antismash"
                     /translation="MYVIYTSGSTGTPKGVAVTH"
     CDS_motif       12852..12938
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioK_0003"
                     /evalue="1.20E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="tioK"
                     /protein_end="364"
                     /protein_start="335"
                     /score="46.3"
                     /tool="antismash"
                     /translation="NGRDGELYLAGNGLARGYLNRPGLTASRF"
     CDS_motif       13023..13088
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioK_0004"
                     /evalue="3.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="tioK"
                     /protein_end="414"
                     /protein_start="392"
                     /score="35.3"
                     /tool="antismash"
                     /translation="FASRGDDQVKIRGFRVELGEVE"
     aSDomain        13401..13604
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioK_PCP.1"
                     /evalue="7.20E-19"
                     /label="tioK_PCP.1"
                     /locus_tag="tioK"
                     /protein_end="586"
                     /protein_start="518"
                     /score="59.6"
                     /tool="antismash"
                     /translation="ESRLCLLVRELLAVPDVRPGDNFFKLGGHSVLATRLAGRLRDEWG
                     ITVPIRAVFEAATLSELALVVQA"
     gene            complement(13731..15005)
                     /gene="tioL"
     CDS             complement(13731..15005)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q333V4"
                     /gene="tioL"
                     /product="hypothetical protein"
                     /protein_id="CAJ34368.1"
                     /transl_table=11
                     /translation="MTGVRTLTVVAILALTATSHQVEPVAASGDVLGVATLADTQTTHA
                     LIANPHLRGTGSTSSGPGGAPAEALSRFHDLGSLAGPGTPSEATDLNDRGDVVGVTSLP
                     GTQTAHAFIANPRHKGGRLIEITPSQAGSSRAQAINRFGVVAGTLGLGIGPPTPAPDGS
                     QPLLQPFVWEARTGLDVLPLPPGAGGAQAVDINDKGTVLVVGTNATGVGLPVGSYLWNP
                     ASRTYTTLPPPTTSVTGPVALAHTLDERGGVAGGLVTQVGEQSWHHTAVVWQPGTLAVQ
                     QLPTGGSADTYATDRNENGLIVGWRINATGQSTTAIYWPSANAQPVELPGRVAYRVNDA
                     GQIVGIRNFTGSSAYPFSAVMWEPRRGRTTRLGDNDLGSYVIAVNASGRSAGFAVATRN
                     GNNHNTAGWWGPPRRGDCPRHCSPR"
     gene            complement(15002..16354)
                     /gene="tioM"
     CDS             complement(15002..16354)
                     /codon_start=1
                     /db_xref="GOA:Q333V3"
                     /db_xref="InterPro:IPR000326"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="InterPro:IPR016119"
                     /db_xref="UniProtKB/TrEMBL:Q333V3"
                     /gene="tioM"
                     /product="V-chloroperoxidase"
                     /protein_id="CAJ34369.1"
                     /transl_table=11
                     /translation="MTTRSTEPSLSPLVPGLSRRGLLIAAASTAAGTAGLLILPTKAEA
                     ATASPRHGSRPDVVGPWFDEMLATFAAAPTAGLPERMWAMSWIAAWAALSARRAAPVRA
                     PGQRAVFEDAATATAVHGVLKALVPGQADKLDGVLADSLAGLAASEAKKAGIAAGREAA
                     AAMVAVRTGDGLDLASVNVPFTLPPEAPGVYRLTPGATQTVAAGYGLARPFLLGRADRF
                     RPPPPPALGTAPYRRALDEVRRLGGEVSERTEAQSDLAWLDPLSQYVPVLRLLVGDSAR
                     SRRSKVRLLAALGAAIVDSSIATFEAKYALLHWRPVTAIRDADTDGDPRTAPDPTWNSF
                     LPTPPHPEYPSGHAVTAGAAEQVLSQLVGPCTPMAFSITFARGDGRVVTRNYRRGTPWS
                     TLTKENIDARVLAGVHFRYSDEVGAALGRQVARYDLNLLARGGVGPVRVTW"
     gene            complement(16438..18744)
                     /gene="tioN"
     CDS             complement(16438..18744)
                     /NRPS_PKS="Domain: AMP-binding (398-677). E-value: 5.6e-66.
                     Score: 214.6. Matches aSDomain:
                     nrpspksdomains_tioN_AMP-binding.1"
                     /codon_start=1
                     /db_xref="GOA:Q333V2"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="UniProtKB/TrEMBL:Q333V2"
                     /gene="tioN"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     235.5; E-value: 1.5e-71)"
                     /gene_kind="biosynthetic-additional"
                     /product="NRPS protein"
                     /protein_id="CAJ34370.1"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-86, bitscore:
                     282.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPWSVWNQTARHFRADVTIPDLLAEAAERHPDRPAIVTSDKQVLT
                     HRELHRRANRLARLLRDLGVGRGDTVALFGERDAPALVGLLAVLKCGAAYVPIDPSWPA
                     RRVVGLLDQLDVAAVLTDRTHLRSMQELRWQVRSLRHVLCPDIAEEFSWSATFRPDLVV
                     NFFDFVSSAPDQLEAAGFNMRRSERPFDENDVQQYRDHVAAFALAATAAARPSILEIGS
                     GSGLIVEALAPRASRYVAADPSPVSVTRSQEGGFRAGGEVDGVVCFAHEVAERVQGPFD
                     VILLASTVQFLPDLDYLLSVLGSLLGLLADDGVIVLADLIDPDLSDYSGIRVAPHFIER
                     LPEFLPGVTGGSVHRRQVETFTGELAQRYDAVIRVAPSGDRPASGREPLWTGHHIELRP
                     SEPLATGPTADDVCYTIFTSGSTGAPKGVVVSHRSAVNLIDWVNRSYRVGPTDQILFVT
                     SFCFDLSVYDIFGVLAAGGSVRLASAAELAEPDTLVDLLEQEEITIWDSAPAALAMVMP
                     FVQVREPAGRGTLRLVLLSGDWIPVPLPDQIRAAFPNAEVVALGGATECTVWSNHYRVG
                     DVDPGWPSIPYGKPMQNARYYVLDHGLGPCPNGAEGDLYIAGECVALGYARSPGLTAAK
                     FLPDPWAHRTGERMYHTGDRARWLPSGDLEFLGRLDDQVKVRGYRIELGEVQSALLQCA
                     GVRAASVVAPSGPGGRTLAAFYVPTAEPLPTAEVVGALQRILPSYMVPTRIVALDELPL
                     TNTGKVDRAALLSRL"
     CDS_motif       complement(16687..16749)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioN_0005"
                     /evalue="7.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="tioN"
                     /protein_end="686"
                     /protein_start="665"
                     /score="37.2"
                     /tool="antismash"
                     /translation="FLGRLDDQVKVRGYRIELGEV"
     aSDomain        complement(16714..17550)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioN_AMP-binding.1"
                     /evalue="5.60E-66"
                     /label="tioN_AMP-binding.1"
                     /locus_tag="tioN"
                     /protein_end="677"
                     /protein_start="398"
                     /score="214.6"
                     /tool="antismash"
                     /translation="PSEPLATGPTADDVCYTIFTSGSTGAPKGVVVSHRSAVNLIDWVN
                     RSYRVGPTDQILFVTSFCFDLSVYDIFGVLAAGGSVRLASAAELAEPDTLVDLLEQEEI
                     TIWDSAPAALAMVMPFVQVREPAGRGTLRLVLLSGDWIPVPLPDQIRAAFPNAEVVALG
                     GATECTVWSNHYRVGDVDPGWPSIPYGKPMQNARYYVLDHGLGPCPNGAEGDLYIAGEC
                     VALGYARSPGLTAAKFLPDPWAHRTGERMYHTGDRARWLPSGDLEFLGRLDDQVKVR"
     CDS_motif       complement(16837..16926)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioN_0004"
                     /evalue="6.50E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="tioN"
                     /protein_end="636"
                     /protein_start="606"
                     /score="31.3"
                     /tool="antismash"
                     /translation="PNGAEGDLYIAGECVALGYARSPGLTAAKF"
     CDS_motif       complement(17314..17337)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioN_0003"
                     /evalue="3.70E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="tioN"
                     /protein_end="477"
                     /protein_start="469"
                     /score="-1.1"
                     /tool="antismash"
                     /translation="FGVLAAGG"
     CDS_motif       complement(17449..17505)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioN_0002"
                     /evalue="3.80E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="tioN"
                     /protein_end="432"
                     /protein_start="413"
                     /score="28.6"
                     /tool="antismash"
                     /translation="YTIFTSGSTGAPKGVVVSH"
     CDS_motif       complement(18448..18489)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioN_0001"
                     /evalue="5.20E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="tioN"
                     /protein_end="99"
                     /protein_start="85"
                     /score="19.5"
                     /tool="antismash"
                     /translation="LAVLKCGAAYVPID"
     gene            complement(18771..19055)
                     /gene="tioO"
     CDS             complement(18771..19055)
                     /NRPS_PKS="Domain: ACP (18-86). E-value: 2.1e-16. Score:
                     51.9. Matches aSDomain: nrpspksdomains_tioO_ACP.1"
                     /codon_start=1
                     /db_xref="GOA:Q333V1"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="UniProtKB/TrEMBL:Q333V1"
                     /function="putative loading module"
                     /gene="tioO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /product="putative 3-hydroxy-quinaldate Carrier Protein"
                     /protein_id="CAJ34371.1"
                     /sec_met_domain="PP-binding (E-value: 4.3e-14, bitscore:
                     44.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANPDRDGNDGSARGLLRAHVRAGWAAALQHERFDNDDDFFAIGG
                     HSLLIAEIMAGLGALAGTRLSLKLFFDHPTVNELTDALAAHEAFGSLAR"
     aSDomain        complement(18798..19001)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioO_ACP.1"
                     /evalue="2.10E-16"
                     /label="tioO_ACP.1"
                     /locus_tag="tioO"
                     /protein_end="86"
                     /protein_start="18"
                     /score="51.9"
                     /tool="antismash"
                     /translation="AHVRAGWAAALQHERFDNDDDFFAIGGHSLLIAEIMAGLGALAGT
                     RLSLKLFFDHPTVNELTDALAAH"
     CDS_motif       complement(18912..18941)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioO_0001"
                     /evalue="7.00E-03"
                     /label="PCP_mC"
                     /locus_tag="tioO"
                     /protein_end="48"
                     /protein_start="38"
                     /score="9.8"
                     /tool="antismash"
                     /translation="DFFAIGGHSL"
     gene            19260..20039
                     /gene="tioP"
     CDS             19260..20039
                     /NRPS_PKS="Domain: Thioesterase (22-247). E-value: 8.5e-33.
                     Score: 106.5. Matches aSDomain:
                     nrpspksdomains_tioP_Thioesterase.1"
                     /codon_start=1
                     /db_xref="GOA:Q333V0"
                     /db_xref="InterPro:IPR001031"
                     /db_xref="InterPro:IPR012223"
                     /db_xref="UniProtKB/TrEMBL:Q333V0"
                     /gene="tioP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 171.9; E-value: 2e-52)"
                     /gene_kind="biosynthetic-additional"
                     /product="thioesterase"
                     /protein_id="CAJ34372.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.1e-11, bitscore:
                     34.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTRTKNRWFVEVSRSRLKECALYAIPHAGGGVATVRSLCVELGD
                     AFDTFGVRLPGRESRLGDPVVTVMSRLADELAGELLRHAQGRPVVLYGHCSGSAIAYEV
                     ARRMDPAQLRGLAVSSHPAPGSVRRAPTWELPRQEFLKQVVTDGYLPPEIIANEELLDI
                     YEPAVRADYELVETYELDLFGGGPVEAVAAPTVAIHGRDDHTIDPVHIDAWSALTTGPF
                     RVVSLAGGHNLLLGRPAELAAAICQGLASDNRLHDHR"
     aSDomain        19326..20000
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioP_Thioesterase.1"
                     /evalue="8.50E-33"
                     /label="tioP_Thioesterase.1"
                     /locus_tag="tioP"
                     /protein_end="247"
                     /protein_start="22"
                     /score="106.5"
                     /tool="antismash"
                     /translation="LYAIPHAGGGVATVRSLCVELGDAFDTFGVRLPGRESRLGDPVVT
                     VMSRLADELAGELLRHAQGRPVVLYGHCSGSAIAYEVARRMDPAQLRGLAVSSHPAPGS
                     VRRAPTWELPRQEFLKQVVTDGYLPPEIIANEELLDIYEPAVRADYELVETYELDLFGG
                     GPVEAVAAPTVAIHGRDDHTIDPVHIDAWSALTTGPFRVVSLAGGHNLLLGRPAELAAA
                     ICQ"
     CDS_motif       19518..19583
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioP_0001"
                     /evalue="3.40E-08"
                     /label="NRPS-te1"
                     /locus_tag="tioP"
                     /protein_end="108"
                     /protein_start="86"
                     /score="26.0"
                     /tool="antismash"
                     /translation="RPVVLYGHCSGSAIAYEVARRM"
     gene            complement(20143..20880)
                     /gene="tioQ"
     CDS             complement(20143..20880)
                     /NRPS_PKS="Domain: Thioesterase (18-228). E-value: 2.5e-40.
                     Score: 131.1. Matches aSDomain:
                     nrpspksdomains_tioQ_Thioesterase.1"
                     /codon_start=1
                     /db_xref="GOA:Q333U9"
                     /db_xref="InterPro:IPR001031"
                     /db_xref="InterPro:IPR012223"
                     /db_xref="UniProtKB/TrEMBL:Q333U9"
                     /gene="tioQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 224.4; E-value: 1.9e-68)"
                     /gene_kind="biosynthetic-additional"
                     /product="thioesterase"
                     /protein_id="CAJ34373.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.8e-12, bitscore:
                     38.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKKGWIRTLTTVEKPTGRLVCFPHSGGSATAFSDWANAMPPGVE
                     LVAVQYPGRGDRFAEHLVDDVAEMAGHIVVELLELPCRDQVLFGHSLGAMVAYETAMLL
                     RDMRVEPRRLCASACLPPGQMKNRDVHLKPDDEFWAAICALGGIDPRVAEIAELRELFM
                     PTLRSDLRAHANYRPGSGTTPLSCPVSCYHGVGDPLVDESRLTEWADVTTGEFRLTVRP
                     GGHFHVSIDVDGLVSDIMGREWA"
     aSDomain        complement(20197..20826)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioQ_Thioesterase.1"
                     /evalue="2.50E-40"
                     /label="tioQ_Thioesterase.1"
                     /locus_tag="tioQ"
                     /protein_end="228"
                     /protein_start="18"
                     /score="131.1"
                     /tool="antismash"
                     /translation="RLVCFPHSGGSATAFSDWANAMPPGVELVAVQYPGRGDRFAEHLV
                     DDVAEMAGHIVVELLELPCRDQVLFGHSLGAMVAYETAMLLRDMRVEPRRLCASACLPP
                     GQMKNRDVHLKPDDEFWAAICALGGIDPRVAEIAELRELFMPTLRSDLRAHANYRPGSG
                     TTPLSCPVSCYHGVGDPLVDESRLTEWADVTTGEFRLTVRPGGHFHV"
     CDS_motif       complement(20569..20625)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioQ_0001"
                     /evalue="2.80E-06"
                     /label="NRPS-te1"
                     /locus_tag="tioQ"
                     /protein_end="104"
                     /protein_start="85"
                     /score="19.9"
                     /tool="antismash"
                     /translation="VLFGHSLGAMVAYETAMLL"
     gene            21188..28972
                     /gene="tioR"
     CDS             21188..28972
                     /NRPS_PKS="Domain: Condensation_Starter (5-310). E-value:
                     6.2e-50. Score: 162.0. Matches aSDomain:
                     nrpspksdomains_tioR_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (474-874). E-value: 3.8e-90.
                     Score: 294.2. Matches aSDomain:
                     nrpspksdomains_tioR_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (994-1060). E-value: 8.1e-22. Score:
                     69.1. Matches aSDomain: nrpspksdomains_tioR_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1080-1385). E-value:
                     7.7e-112. Score: 366.2. Matches aSDomain:
                     nrpspksdomains_tioR_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1399-1560). E-value: 8.6e-34.
                     Score: 108.4. Matches aSDomain:
                     nrpspksdomains_tioR_TIGR01720.1"
                     /NRPS_PKS="Domain: Cglyc (1566-1864). E-value: 2e-92.
                     Score: 301.4. Matches aSDomain:
                     nrpspksdomains_tioR_Cglyc.1"
                     /NRPS_PKS="Domain: AMP-binding (2027-2404). E-value:
                     1.5e-110. Score: 361.5. Matches aSDomain:
                     nrpspksdomains_tioR_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2511-2576). E-value: 5.5e-28.
                     Score: 88.9. Matches aSDomain: nrpspksdomains_tioR_PCP.2"
                     /codon_start=1
                     /db_xref="GOA:Q333U8"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010060"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="UniProtKB/TrEMBL:Q333U8"
                     /function="thiocoraline NRPS (modules 1 and 2)"
                     /gene="tioR"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     386.2; E-value: 3.3e-117)"
                     /gene_kind="biosynthetic"
                     /product="NRPS protein"
                     /protein_id="CAJ34374.1"
                     /sec_met_domain="Condensation (E-value: 4.8e-64, bitscore:
                     207.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7.6e-115, bitscore:
                     375.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.6e-19, bitscore:
                     60.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGYGGVSSAQEAMWLEQNLAPEVPNSTTTIWDVRGELHLPDLEDA
                     LRTALGETSALLVNFRRESDELRIVPRKLDAWEPFRIDASDAADPAAAAREFLTEQIRR
                     PFDLGADALFRIGTVRLGDGHHLLCLIMHHILTDAFGVFTLLSQRVAEIYRALRADSPV
                     PDRPDTPAEIAGEREATYRSSERFTDAARFWRDYVTAGGTAARLPTGMRAGATRTASVG
                     FWDGLTAPLGVASYTASVAASEVARWRAAADSTETSVPDLLTSAATAFLHRLCNTPRPM
                     LSFTVNYRRGDIKQACGLYSNALPLVIEVPAAGDFVDLAKSVRLERLRVLRYAEYNVSL
                     IKRAAGHAGDVRSPFGPVVNVIPFLRELDLAGAVGRFAGGTFGLPDEVRISTYVDGGPD
                     SDLYIRFDAPGRLYTHEDIAGLAERFVTFVRAALTDPRARVRDISAIGEQERVALLDRC
                     AGPVVELAGVTVPVLLDMQALATPDAAAVVHENAVLTYRELAARSDALARRLAECGAGP
                     ERLVAVAVPRSIGLAVALCAVLKAGAAYLPIDPDSPAERVEFMLGDARPTLLLTVAGTD
                     GLAITPLHGAQPRWEASVIERTTAASPAATSQAGGTGEHAAYLRYRSGPFGPAAGVVVT
                     HAALVNELLWMQQRYRLNDTDRVLHKAPASLNASGWEIFWPLIAGATVVMATQDVHGDA
                     TALAAMIRRTGVTTVHVVPSVLAELVRDEAVVTAGKGLRHVMCSGEVLPADLAARFHES
                     CDVPVHSLYGPVEAMPVVTSCDYRPGSPTVPLGRPISNAGVYVLDSQLQLTPPGVVGEV
                     YVTGVGLARGYLHRPAATADHFVACPFGPAGTRMYRTGDLARWTDDGELEHAGSADQRV
                     RIRGFWAAFLEIEAVLTAHPGVDQAAVIARPDGPDRAAQLIAYVVPATGGRMGAAGLDV
                     DFSAGLDVVELRRFVAARLPEHLVPATIVVLDRLPLTAEGKRDHAALPEPQATRRAHRV
                     ARTAEERLLADAFAEVLGAGRIGLDDDFFALGGDSISAMRVVALARAGGLALTARTVFE
                     CRTVAALAAVAAPADEPAVAAAAEGDGGRDDAGPIPLPPMARLFAERGPGLDRLAQWLV
                     LTLPAEMSPDLLTGAVRAVLDRHDVLRSRLADGQLLIQPPGSVDVDKLIRQVPCSGDWS
                     GPSWPALLADEAAKAVGQLSASAGQVIRMVWFAPPGGAPGRLLIAAHHLVVDGMSWRVL
                     VPDLAEAAAQIRSGRTPALAPVGTSLRSWLDELAAEAVRPERVAELELWRGILAPSGDP
                     LGARPLDPAVDLTRTAQTLRVEVPAELSRALLTSVPATFRCGVDDVLLTALALALASRR
                     HNSAGVVRLEGHGRQEELVPGTDLTRTVGWFTTVHPVRFDLSGLDLTDAINGGPAAAEA
                     LRRVKESRRVLPDRGIGYSLLRYLNQATGAMLRDLPADEVGFNYLGRFSFDRSRTGREM
                     AWTSAPESAALVAAPDPDMPLISALELNSLVVDTDHGEQLQALFTFATGVLATDEVRHL
                     ADDWQAALRGIRAQAATGASGLTPSDVPLVRVRQQDLDDWQSRFGRVDDVWPLTPLQHG
                     LLYHSLLGDSAAASYQTQFVLRINGPVDPARLRGAAQTLLNRHPNLRVAFLTKSTGEPV
                     QVVVDGVEVPFAHVDLAGQPQAEERLARILAEEREAQFRHDSAPLLRFSLITLTPTQAE
                     LALTAHHVLFDGWSLPLIEQQLMHLYAGGADALELVEHGYREFLRWHSRQNADEALAAW
                     TEELADATQPTLLASGFAPAEQAGTSTEIGQVDVLLTRQEAASAVRRAADCGITPNVLV
                     QGAWAVVLAQLTGNADVLFGSSVTVRPPELPGAHTVVGMFTNTVPVRVRCAPADSLEGM
                     LQAVQDAQARTLDHYHVGLGDIQRATGLTTLFDTIVIFESFPVDRAALSKASASAELTV
                     TGIRPFAPTHYPLTVLAAADPLLSLTLQYHPDALAPSTVQAIADRFARVLRQFAADPRT
                     RIAAIDVLSEAERQLVVHDWNATALEVPPEFVPEQFARQAAATPDAVAVVVGEQHLTYA
                     ELSERANRMAHWLIAQGIGAESRVVVLLPRSADLVAALLAVWQAGGCYVPVDPDYPAAR
                     VRSVIDDCAATLVLDENLLDRTDLSRYPAHAPAIAVAPGQAAYTIYTSGSTGKPKGVVI
                     GHDALTNFLASMQRTLRLSAQDRFAAVTTIAFDIAALELFLPLTTGARVVLANREHVAN
                     PPAMLDLVEQTGVTVMQATPALWQMLATHDVRRLSGVRVLTGGEALPRPLAEGLCAHAA
                     QVINLYGPTETTVWSTLADVATCKPPSIGTPIANTQVLILDSALRPVPPGVGGDLWIAG
                     DGLARGYHRQPGLTASRFVANPFGPQGARMYRTGDLARWSESGRIEFLGRADFQIKLRG
                     FRIEPGDVEHALTRHPAVREAVVTIREDQPDDKRLVGYVVVAEDAETPPTRELQQFVRE
                     QLPDYMVPSAVVTLPAIPLTANGKLDRSRLPRPEASSTKYRAPESAREVALCGIFAEVL
                     GAERVGVDDDFFALGGHSLLATRLAARLRSDLGVEVPIRTIFAAPTVAELARRWSGLST
                     SVRKPLRRMTER"
     aSDomain        21203..22117
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioR_Condensation_Starter.1"
                     /domain_subtype="Condensation_Starter"
                     /evalue="6.20E-50"
                     /label="tioR_Condensation_Starter.1"
                     /locus_tag="tioR"
                     /protein_end="310"
                     /protein_start="5"
                     /score="162.0"
                     /tool="antismash"
                     /translation="VSSAQEAMWLEQNLAPEVPNSTTTIWDVRGELHLPDLEDALRTAL
                     GETSALLVNFRRESDELRIVPRKLDAWEPFRIDASDAADPAAAAREFLTEQIRRPFDLG
                     ADALFRIGTVRLGDGHHLLCLIMHHILTDAFGVFTLLSQRVAEIYRALRADSPVPDRPD
                     TPAEIAGEREATYRSSERFTDAARFWRDYVTAGGTAARLPTGMRAGATRTASVGFWDGL
                     TAPLGVASYTASVAASEVARWRAAADSTETSVPDLLTSAATAFLHRLCNTPRPMLSFTV
                     NYRRGDIKQACGLYSNALPLVIEV"
     aSModule        21203..25867
                     /complete
                     /domains="nrpspksdomains_tioR_Condensation_Starter.1"
                     /domains="nrpspksdomains_tioR_AMP-binding.1"
                     /domains="nrpspksdomains_tioR_PCP.1"
                     /domains="nrpspksdomains_tioR_Epimerization.1"
                     /domains="nrpspksdomains_tioR_TIGR01720.1"
                     /locus_tags="tioR"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       21278..21367
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0001"
                     /evalue="8.90E-02"
                     /label="C2_starter_024-063"
                     /locus_tag="tioR"
                     /protein_end="60"
                     /protein_start="30"
                     /score="5.6"
                     /tool="antismash"
                     /translation="WDVRGELHLPDLEDALRTALGETSALLVNF"
     CDS_motif       21584..21649
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0002"
                     /evalue="5.70E-08"
                     /label="C3_starter_134-155"
                     /locus_tag="tioR"
                     /protein_end="154"
                     /protein_start="132"
                     /score="25.6"
                     /tool="antismash"
                     /translation="HHILTDAFGVFTLLSQRVAEIY"
     CDS_motif       22160..22270
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0003"
                     /evalue="2.90E-08"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="tioR"
                     /protein_end="361"
                     /protein_start="324"
                     /score="26.3"
                     /tool="antismash"
                     /translation="LERLRVLRYAEYNVSLIKRAAGHAGDVRSPFGPVVNV"
     aSDomain        22610..23809
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioR_AMP-binding.1"
                     /evalue="3.80E-90"
                     /label="tioR_AMP-binding.1"
                     /locus_tag="tioR"
                     /protein_end="874"
                     /protein_start="474"
                     /score="294.2"
                     /tool="antismash"
                     /translation="DMQALATPDAAAVVHENAVLTYRELAARSDALARRLAECGAGPER
                     LVAVAVPRSIGLAVALCAVLKAGAAYLPIDPDSPAERVEFMLGDARPTLLLTVAGTDGL
                     AITPLHGAQPRWEASVIERTTAASPAATSQAGGTGEHAAYLRYRSGPFGPAAGVVVTHA
                     ALVNELLWMQQRYRLNDTDRVLHKAPASLNASGWEIFWPLIAGATVVMATQDVHGDATA
                     LAAMIRRTGVTTVHVVPSVLAELVRDEAVVTAGKGLRHVMCSGEVLPADLAARFHESCD
                     VPVHSLYGPVEAMPVVTSCDYRPGSPTVPLGRPISNAGVYVLDSQLQLTPPGVVGEVYV
                     TGVGLARGYLHRPAATADHFVACPFGPAGTRMYRTGDLARWTDDGELEHAGSADQRVRI
                     R"
     CDS_motif       22796..22834
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0004"
                     /evalue="7.80E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="tioR"
                     /protein_end="549"
                     /protein_start="536"
                     /score="15.9"
                     /tool="antismash"
                     /translation="AVLKAGAAYLPID"
     CDS_motif       23036..23095
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0005"
                     /evalue="8.10E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="tioR"
                     /protein_end="636"
                     /protein_start="616"
                     /score="9.4"
                     /tool="antismash"
                     /translation="AYLRYRSGPFGPAAGVVVTH"
     CDS_motif       23600..23689
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0006"
                     /evalue="1.70E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="tioR"
                     /protein_end="834"
                     /protein_start="804"
                     /score="45.9"
                     /tool="antismash"
                     /translation="PPGVVGEVYVTGVGLARGYLHRPAATADHF"
     CDS_motif       23777..23839
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0007"
                     /evalue="1.70E-01"
                     /label="NRPS-A_a8"
                     /locus_tag="tioR"
                     /protein_end="884"
                     /protein_start="863"
                     /score="5.0"
                     /tool="antismash"
                     /translation="AGSADQRVRIRGFWAAFLEIE"
     aSDomain        24170..24367
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioR_PCP.1"
                     /evalue="8.10E-22"
                     /label="tioR_PCP.1"
                     /locus_tag="tioR"
                     /protein_end="1060"
                     /protein_start="994"
                     /score="69.1"
                     /tool="antismash"
                     /translation="ERLLADAFAEVLGAGRIGLDDDFFALGGDSISAMRVVALARAGGL
                     ALTARTVFECRTVAALAAVAA"
     aSDomain        24428..25342
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioR_Epimerization.1"
                     /evalue="7.70E-112"
                     /label="tioR_Epimerization.1"
                     /locus_tag="tioR"
                     /protein_end="1385"
                     /protein_start="1080"
                     /score="366.2"
                     /tool="antismash"
                     /translation="GPIPLPPMARLFAERGPGLDRLAQWLVLTLPAEMSPDLLTGAVRA
                     VLDRHDVLRSRLADGQLLIQPPGSVDVDKLIRQVPCSGDWSGPSWPALLADEAAKAVGQ
                     LSASAGQVIRMVWFAPPGGAPGRLLIAAHHLVVDGMSWRVLVPDLAEAAAQIRSGRTPA
                     LAPVGTSLRSWLDELAAEAVRPERVAELELWRGILAPSGDPLGARPLDPAVDLTRTAQT
                     LRVEVPAELSRALLTSVPATFRCGVDDVLLTALALALASRRHNSAGVVRLEGHGRQEEL
                     VPGTDLTRTVGWFTTVHPVRFDLS"
     CDS_motif       24533..24595
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0008"
                     /evalue="3.40E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="tioR"
                     /protein_end="1136"
                     /protein_start="1115"
                     /score="16.3"
                     /tool="antismash"
                     /translation="PDLLTGAVRAVLDRHDVLRSR"
     CDS_motif       24809..24874
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0009"
                     /evalue="1.20E-10"
                     /label="NRPS-E2"
                     /locus_tag="tioR"
                     /protein_end="1229"
                     /protein_start="1207"
                     /score="33.5"
                     /tool="antismash"
                     /translation="LLIAAHHLVVDGMSWRVLVPDL"
     CDS_motif       25283..25333
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0010"
                     /evalue="6.90E-08"
                     /label="NRPS-E5"
                     /locus_tag="tioR"
                     /protein_end="1382"
                     /protein_start="1365"
                     /score="24.6"
                     /tool="antismash"
                     /translation="DLTRTVGWFTTVHPVRF"
     aSDomain        25385..25867
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioR_TIGR01720.1"
                     /evalue="8.60E-34"
                     /label="tioR_TIGR01720.1"
                     /locus_tag="tioR"
                     /protein_end="1560"
                     /protein_start="1399"
                     /score="108.4"
                     /tool="antismash"
                     /translation="AEALRRVKESRRVLPDRGIGYSLLRYLNQATGAMLRDLPADEVGF
                     NYLGRFSFDRSRTGREMAWTSAPESAALVAAPDPDMPLISALELNSLVVDTDHGEQLQA
                     LFTFATGVLATDEVRHLADDWQAALRGIRAQAATGASGLTPSDVPLVRVRQQDLDDW"
     CDS_motif       25403..25465
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0011"
                     /evalue="3.70E-08"
                     /label="NRPS-E6"
                     /locus_tag="tioR"
                     /protein_end="1426"
                     /protein_start="1405"
                     /score="25.7"
                     /tool="antismash"
                     /translation="VKESRRVLPDRGIGYSLLRYL"
     aSDomain        25886..26779
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioR_Cglyc.1"
                     /domain_subtype="Cglyc"
                     /evalue="2.00E-92"
                     /label="tioR_Cglyc.1"
                     /locus_tag="tioR"
                     /protein_end="1864"
                     /protein_start="1566"
                     /score="301.4"
                     /tool="antismash"
                     /translation="VDDVWPLTPLQHGLLYHSLLGDSAAASYQTQFVLRINGPVDPARL
                     RGAAQTLLNRHPNLRVAFLTKSTGEPVQVVVDGVEVPFAHVDLAGQPQAEERLARILAE
                     EREAQFRHDSAPLLRFSLITLTPTQAELALTAHHVLFDGWSLPLIEQQLMHLYAGGADA
                     LELVEHGYREFLRWHSRQNADEALAAWTEELADATQPTLLASGFAPAEQAGTSTEIGQV
                     DVLLTRQEAASAVRRAADCGITPNVLVQGAWAVVLAQLTGNADVLFGSSVTVRPPELPG
                     AHTVVGMFTNTVPVRVR"
     aSModule        25886..28915
                     /complete
                     /domains="nrpspksdomains_tioR_Cglyc.1"
                     /domains="nrpspksdomains_tioR_AMP-binding.2"
                     /domains="nrpspksdomains_tioR_PCP.2"
                     /locus_tags="tioR"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       25901..25936
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0012"
                     /evalue="2.00E-03"
                     /label="C1_dual_004-017"
                     /locus_tag="tioR"
                     /protein_end="1583"
                     /protein_start="1571"
                     /score="11.2"
                     /tool="antismash"
                     /translation="PLTPLQHGLLYH"
     CDS_motif       25961..26077
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0013"
                     /evalue="1.40E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="tioR"
                     /protein_end="1630"
                     /protein_start="1591"
                     /score="46.3"
                     /tool="antismash"
                     /translation="ASYQTQFVLRINGPVDPARLRGAAQTLLNRHPNLRVAFL"
     CDS_motif       26072..26113
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0014"
                     /evalue="1.20E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="tioR"
                     /protein_end="1642"
                     /protein_start="1628"
                     /score="-0.2"
                     /tool="antismash"
                     /translation="FLTKSTGEPVQVVV"
     CDS_motif       26294..26356
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0015"
                     /evalue="4.80E-08"
                     /label="C3_DCL_135-156"
                     /locus_tag="tioR"
                     /protein_end="1723"
                     /protein_start="1702"
                     /score="25.5"
                     /tool="antismash"
                     /translation="HHVLFDGWSLPLIEQQLMHLY"
     CDS_motif       26678..26773
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0016"
                     /evalue="4.00E-13"
                     /label="C5_DCL_263-294"
                     /locus_tag="tioR"
                     /protein_end="1862"
                     /protein_start="1830"
                     /score="41.8"
                     /tool="antismash"
                     /translation="DVLFGSSVTVRPPELPGAHTVVGMFTNTVPVR"
     CDS_motif       26822..26935
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0017"
                     /evalue="1.30E-12"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="tioR"
                     /protein_end="1916"
                     /protein_start="1878"
                     /score="40.0"
                     /tool="antismash"
                     /translation="QDAQARTLDHYHVGLGDIQRATGLTTLFDTIVIFESFP"
     aSDomain        27269..28399
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioR_AMP-binding.2"
                     /evalue="1.50E-110"
                     /label="tioR_AMP-binding.2"
                     /locus_tag="tioR"
                     /protein_end="2404"
                     /protein_start="2027"
                     /score="361.5"
                     /tool="antismash"
                     /translation="FARQAAATPDAVAVVVGEQHLTYAELSERANRMAHWLIAQGIGAE
                     SRVVVLLPRSADLVAALLAVWQAGGCYVPVDPDYPAARVRSVIDDCAATLVLDENLLDR
                     TDLSRYPAHAPAIAVAPGQAAYTIYTSGSTGKPKGVVIGHDALTNFLASMQRTLRLSAQ
                     DRFAAVTTIAFDIAALELFLPLTTGARVVLANREHVANPPAMLDLVEQTGVTVMQATPA
                     LWQMLATHDVRRLSGVRVLTGGEALPRPLAEGLCAHAAQVINLYGPTETTVWSTLADVA
                     TCKPPSIGTPIANTQVLILDSALRPVPPGVGGDLWIAGDGLARGYHRQPGLTASRFVAN
                     PFGPQGARMYRTGDLARWSESGRIEFLGRADFQIKLR"
     CDS_motif       27455..27496
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0018"
                     /evalue="3.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="tioR"
                     /protein_end="2103"
                     /protein_start="2089"
                     /score="14.0"
                     /tool="antismash"
                     /translation="LAVWQAGGCYVPVD"
     CDS_motif       27641..27700
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0019"
                     /evalue="5.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="tioR"
                     /protein_end="2171"
                     /protein_start="2151"
                     /score="28.2"
                     /tool="antismash"
                     /translation="AYTIYTSGSTGKPKGVVIGH"
     CDS_motif       28190..28279
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0020"
                     /evalue="3.60E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="tioR"
                     /protein_end="2364"
                     /protein_start="2334"
                     /score="44.8"
                     /tool="antismash"
                     /translation="PPGVGGDLWIAGDGLARGYHRQPGLTASRF"
     CDS_motif       28364..28429
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioR_0021"
                     /evalue="1.00E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="tioR"
                     /protein_end="2414"
                     /protein_start="2392"
                     /score="33.6"
                     /tool="antismash"
                     /translation="FLGRADFQIKLRGFRIEPGDVE"
     aSDomain        28721..28915
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioR_PCP.2"
                     /evalue="5.50E-28"
                     /label="tioR_PCP.2"
                     /locus_tag="tioR"
                     /protein_end="2576"
                     /protein_start="2511"
                     /score="88.9"
                     /tool="antismash"
                     /translation="EVALCGIFAEVLGAERVGVDDDFFALGGHSLLATRLAARLRSDLG
                     VEVPIRTIFAAPTVAELARR"
     gene            28979..38401
                     /gene="tioS"
     CDS             28979..38401
                     /NRPS_PKS="Domain: Condensation_LCL (1-300). E-value:
                     1e-105. Score: 344.9. Matches aSDomain:
                     nrpspksdomains_tioS_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (479-885). E-value: 8.4e-96.
                     Score: 312.8. Matches aSDomain:
                     nrpspksdomains_tioS_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (973-1193). E-value: 6.8e-87. Score:
                     283.1. Matches aSDomain: nrpspksdomains_tioS_nMT.1"
                     /NRPS_PKS="Domain: PCP (1387-1455). E-value: 2.2e-27.
                     Score: 86.9. Matches aSDomain: nrpspksdomains_tioS_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1469-1769). E-value:
                     5.1e-114. Score: 372.1. Matches aSDomain:
                     nrpspksdomains_tioS_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1939-2322). E-value:
                     1.5e-102. Score: 335.1. Matches aSDomain:
                     nrpspksdomains_tioS_AMP-binding.2"
                     /NRPS_PKS="Domain: nMT (2414-2634). E-value: 2.1e-95.
                     Score: 311.2. Matches aSDomain: nrpspksdomains_tioS_nMT.2"
                     /NRPS_PKS="Domain: PCP (2819-2887). E-value: 3.6e-25.
                     Score: 79.8. Matches aSDomain: nrpspksdomains_tioS_PCP.2"
                     /NRPS_PKS="Domain: Thioesterase (2911-3131). E-value:
                     2.1e-34. Score: 111.7. Matches aSDomain:
                     nrpspksdomains_tioS_Thioesterase.1"
                     /codon_start=1
                     /db_xref="GOA:Q333U7"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001031"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="InterPro:IPR013217"
                     /db_xref="InterPro:IPR020806"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="UniProtKB/TrEMBL:Q333U7"
                     /function="thiocoraline NRPS (modules 3 and 4)"
                     /gene="tioS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     359.7; E-value: 4.6e-109)"
                     /gene_kind="biosynthetic"
                     /product="NRPS"
                     /protein_id="CAJ34375.1"
                     /sec_met_domain="Condensation (E-value: 2.3e-72, bitscore:
                     234.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6.5e-105, bitscore:
                     342.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-18, bitscore:
                     58.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.5e-07, bitscore: 22.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPVSYAQQRMWFINRFEGQTATYNIPILIRMRGQIDRDELRAAF
                     MDVLSRHEILRTVYDELDGQPLQRIIEPAELSLPWTDWGWVSPQQVDSIVAASVREGFD
                     LSVDLPIRAYLLRPEPDVALLAVVIHHIAGDGGSLGPFTRDLSAAYRARLAGVAPTWDE
                     LPVQYSDYALWQRELLGDESDPDSVFSTQLRYWRQELDGVSRPVALPVDRPRPARASYR
                     GDNHGFEIPAALFEKVERLAQSYNVTVPMVFQTALVVLLHRLGGDRDITLGSPIAGRTD
                     QALENLVGFFVNTWVLRVGVCTGDSFAQVLEQVRQKAIAAYDHQDLPFERLVELLRPGR
                     SVAHHPLFQVTLAWQNSVRQELDLPGVTASMEPVATGTAKFDLFVNLMPNHSRRSVTVD
                     LEYATDLFDPATVEAIAARYLRVLEQVVESPDLGVGILDVPAMPATRGERTVDAGEREK
                     ILYRWNDTDRSFPCPGPIHLPFEQQAAARPDAIAVRWSGGTMTYRELNRQANRIAWTLK
                     RRGVRPETVVGVAVRRGPLMVAAVLGVLKAGGAYLPIGSTLPSDRVAGMLADASATLVL
                     TTEDTNRWTPPDGVELLDVGRAGLALSLDGEINPEPVASADNTAYIIFTSGSTGKPKGV
                     TVAHRPVHNLLNWCYRTFDFGPDDVSLCVTSLDFDLSVFDIFGLLGAGGGFYIADATQQ
                     RDPEMLLDVLLSEPITFWNSVPGTLNQLAPLLPQTAGSPGVQDLRLVFFSGDYTPLSLP
                     DQVRAVFPHAEIISLGGATEATVWSNFFPVGAIDPQWRSIPYGRPIDNARYYVLDEKLE
                     PCAVGVEGDLYIGGPVIALGYVNRPDLTAERFIADPFGGVPGQRIYRTGDRASFFPDGN
                     ICFLGRADGQVKVRGFRIELGEIEYALGRHPAVRQGIAITRRDSVGDLRLVSYVLPDLD
                     TVESVVAADEQVREWQEIYDQGYLEVTDQDFGDDFNLWVSSYTGEPIPVGQMREWQDAA
                     VDRILSFTPRRVLEVGAGTGLLLARVAGSVEAYWATDFSEPVIERLGRQVTEAGWAERV
                     RLLCRRADDLDGIPRIFDTVVLNSVVQYFPNERYLEQVLDGVWAMLEPGGRLVLGDIRR
                     ARSLRAFQVAVQQAKHGNLPPAQLRSAVEQGLLLEKELVIDPEWFQRWAERAGAAGVDV
                     RLKEGAFQNELTRHRYEIVVHKPGTTEAGRPYAVDTVPRLEWNGDLDGLAERIRTLGGP
                     VVRIAGIPNARVAQEVAAARDLGLEESEPPTSVPVDPHEMATWAARQGWSIALTWSGSA
                     VDQFEAVLFTDATTEHRALSGTYLPVAAAGTWINDPAAAAGITALPAVLREYLSKTLPE
                     YMVPSAIVPIGRVPLTPNGKLDRAALPVPEYAAASRGRPPCTSEEESLCEIFAGVLGLD
                     RVGVDDNFFTIGGHSLLATRVVSRIRAAHGVEIPIRTIFEAPTVAELVAHLTGQRTVRP
                     PLRPQPRPDRLPVSFAQQRLWFIHRFEGPSPTYIIPLSMRLRGKLDVPALRQAVHDVVV
                     RHESLRTVFDEVDGAPYQRVLDPDGLAIPWQEHEVTESALQEALRLEARRPFDLAAEIP
                     VRAALFRVGEHDAVLLLPLHHIAADGWSLGPLAEDLTAAYTARCDGQRPQWAALPVQYA
                     DYTLWQRDLLGGDDPHSLYRRQLDYWTGQLAGLPESLQLPTDRARPAVASFAGEVLPVE
                     LDESLTEDLRKLALRTGTTVSMVLQAGLAGLLSKLGAGNDIPIGSPIAGRTDEALNRLV
                     GFFVNTWVARVDTSGSPSLIELVDRVREVSLAAYDHQDIPFEHLVEALNPVRSTAHHPL
                     FQVCLALQNNVQPAFDLPGLKVSHEPVDMGVSRFDLFLNLMEETTGEGTSRIAGVVEYA
                     TELFDRDTVTGLLERWRRLLRQWVGAPDAPIDAVEILNRDDLAALERWTGRARGTDRVV
                     GTIPERFAAVVAEQPEAVALVAADGEESWTYGELDRWANRIAHHLHARGVGRQHRVALV
                     MERSPLLVAAVLGTLKAGACYVPVEPTWPRARIDLVLADLDPALVIDERLAEEDLTGYP
                     TRPLDTADVGGEHLAYLMYTSGSTGTPKGVEVSHRNVLSLALDPCWADADHQRVLVHAP
                     PTFDASTYEMWVPLLHGGAAVVAPPGKLDAARLATLIAERGVTALWLPAGLFDLITQHH
                     PKSFVQVREVWAGGDVLSPAAVRRLVRDDGTLTVVNGYGPTETTTFAARYRMSAPARCK
                     DPLPIGEPMAGSRLYALDDRLRQVPQGVIGELYVGGDGVARGYANHPPLTSERFVADPF
                     GRPGERMYRTGDLVRWNHDGQLEFLGRVDEQVKIRGFRVEPGEIRAALRKRDGVAQAVV
                     VPRTDRLGERRLVAYVVPEVPAGADEDSTEHVEKWRAIYDSMYDETEADATEIGNDFTG
                     WKSSYTRDNIPLSEMRRWRDSVVEEVRGLRARRILEIGVGSGLLLGPLAPEAEAYWGTD
                     FSLPVIERLEVQVGTDPCLKEKVSLRCQHADVADGLPVKYFDTVILNSVVQYFPDAAYL
                     SRVLDVALDRLAPGGRILVGDVRNYGTLREFLTAVHHAQHPQDSASAVRAAVERAVLAE
                     KELVIDPDFFTEWARTRPDVVAVDIRLKPGADQNELTRHRYEVILHKQPSQPLRLADVR
                     TANWGSEVPDLSGLETALARHGGRLRLARIPNARLVSEAVQCGVPTNVGGTPLDPHELA
                     SWGGQRGYSVHCTWSAEAPGWFEAVIIPVDSGHCRDGVYRPVGPRPRQLVNLPAAARRV
                     SRLPSWLREELAAELPEHLVPGDIVVMERLPLTTNGKIDHSRLPEVEQADREYGSPRTP
                     LEAELAGLFAEVLGVDRVGIEDDFFDCGGSSLQVIRLIWRIRAELGFDIPVRTIFQHPT
                     VAEVAEHLAAGREDVEFDDPFSVVLPIRTDGDRAPIWLVPPGGGLSWAYLGFAQHLDRS
                     RPIYGLQARGFVGDPRATSIESMVDDYVDQILRVQPEGPYNVLGWSLGGPIAQAVAAEL
                     QRRECEVDLLAVLDSGPASYFADFQTPDEKLVRRYLAHYMGHLAGMAEFESLVQTSTTL
                     FIEHTDLMTQFTSPPFRGDLIFFAALIDQGTRERRQLEVELDVQWREYTEGTVRRFDIE
                     CAHNEMMWPENAAMISRIVNEIIDSAR"
     aSDomain        28982..29878
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioS_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.00E-105"
                     /label="tioS_Condensation_LCL.1"
                     /locus_tag="tioS"
                     /protein_end="300"
                     /protein_start="1"
                     /score="344.9"
                     /tool="antismash"
                     /translation="APVSYAQQRMWFINRFEGQTATYNIPILIRMRGQIDRDELRAAFM
                     DVLSRHEILRTVYDELDGQPLQRIIEPAELSLPWTDWGWVSPQQVDSIVAASVREGFDL
                     SVDLPIRAYLLRPEPDVALLAVVIHHIAGDGGSLGPFTRDLSAAYRARLAGVAPTWDEL
                     PVQYSDYALWQRELLGDESDPDSVFSTQLRYWRQELDGVSRPVALPVDRPRPARASYRG
                     DNHGFEIPAALFEKVERLAQSYNVTVPMVFQTALVVLLHRLGGDRDITLGSPIAGRTDQ
                     ALENLVGFFVNTWVLRVG"
     aSModule        28982..33343
                     /complete
                     /domains="nrpspksdomains_tioS_Condensation_LCL.1"
                     /domains="nrpspksdomains_tioS_AMP-binding.1"
                     /domains="nrpspksdomains_tioS_nMT.1"
                     /domains="nrpspksdomains_tioS_PCP.1"
                     /locus_tags="tioS"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       28991..29020
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0001"
                     /evalue="6.60E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="tioS"
                     /protein_end="14"
                     /protein_start="4"
                     /score="9.2"
                     /tool="antismash"
                     /translation="SYAQQRMWFI"
     CDS_motif       29042..29155
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0002"
                     /evalue="5.70E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="tioS"
                     /protein_end="59"
                     /protein_start="21"
                     /score="44.4"
                     /tool="antismash"
                     /translation="ATYNIPILIRMRGQIDRDELRAAFMDVLSRHEILRTVY"
     CDS_motif       29363..29428
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0003"
                     /evalue="2.90E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="tioS"
                     /protein_end="150"
                     /protein_start="128"
                     /score="26.3"
                     /tool="antismash"
                     /translation="IHHIAGDGGSLGPFTRDLSAAY"
     CDS_motif       29477..29515
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0004"
                     /evalue="1.40E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="tioS"
                     /protein_end="179"
                     /protein_start="166"
                     /score="17.6"
                     /tool="antismash"
                     /translation="QYSDYALWQRELL"
     CDS_motif       29783..29872
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0005"
                     /evalue="9.40E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="tioS"
                     /protein_end="298"
                     /protein_start="268"
                     /score="50.1"
                     /tool="antismash"
                     /translation="DITLGSPIAGRTDQALENLVGFFVNTWVLR"
     CDS_motif       29921..30040
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0006"
                     /evalue="1.20E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="tioS"
                     /protein_end="354"
                     /protein_start="314"
                     /score="65.9"
                     /tool="antismash"
                     /translation="RQKAIAAYDHQDLPFERLVELLRPGRSVAHHPLFQVTLAW"
     aSDomain        30416..31633
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioS_AMP-binding.1"
                     /evalue="8.40E-96"
                     /label="tioS_AMP-binding.1"
                     /locus_tag="tioS"
                     /protein_end="885"
                     /protein_start="479"
                     /score="312.8"
                     /tool="antismash"
                     /translation="FEQQAAARPDAIAVRWSGGTMTYRELNRQANRIAWTLKRRGVRPE
                     TVVGVAVRRGPLMVAAVLGVLKAGGAYLPIGSTLPSDRVAGMLADASATLVLTTEDTNR
                     WTPPDGVELLDVGRAGLALSLDGEINPEPVASADNTAYIIFTSGSTGKPKGVTVAHRPV
                     HNLLNWCYRTFDFGPDDVSLCVTSLDFDLSVFDIFGLLGAGGGFYIADATQQRDPEMLL
                     DVLLSEPITFWNSVPGTLNQLAPLLPQTAGSPGVQDLRLVFFSGDYTPLSLPDQVRAVF
                     PHAEIISLGGATEATVWSNFFPVGAIDPQWRSIPYGRPIDNARYYVLDEKLEPCAVGVE
                     GDLYIGGPVIALGYVNRPDLTAERFIADPFGGVPGQRIYRTGDRASFFPDGNICFLGRA
                     DGQVKVR"
     CDS_motif       30602..30640
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0007"
                     /evalue="5.00E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="tioS"
                     /protein_end="554"
                     /protein_start="541"
                     /score="13.5"
                     /tool="antismash"
                     /translation="LGVLKAGGAYLPI"
     CDS_motif       30836..30895
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0008"
                     /evalue="2.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="tioS"
                     /protein_end="639"
                     /protein_start="619"
                     /score="29.1"
                     /tool="antismash"
                     /translation="AYIIFTSGSTGKPKGVTVAH"
     CDS_motif       31424..31510
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0009"
                     /evalue="1.50E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="tioS"
                     /protein_end="844"
                     /protein_start="815"
                     /score="42.9"
                     /tool="antismash"
                     /translation="VGVEGDLYIGGPVIALGYVNRPDLTAERF"
     CDS_motif       31598..31663
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0010"
                     /evalue="7.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="tioS"
                     /protein_end="895"
                     /protein_start="873"
                     /score="37.2"
                     /tool="antismash"
                     /translation="FLGRADGQVKVRGFRIELGEIE"
     aSDomain        31898..32557
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioS_nMT.1"
                     /domain_subtype="nMT"
                     /evalue="6.80E-87"
                     /label="tioS_nMT.1"
                     /locus_tag="tioS"
                     /protein_end="1193"
                     /protein_start="973"
                     /score="283.1"
                     /tool="antismash"
                     /translation="GEPIPVGQMREWQDAAVDRILSFTPRRVLEVGAGTGLLLARVAGS
                     VEAYWATDFSEPVIERLGRQVTEAGWAERVRLLCRRADDLDGIPRIFDTVVLNSVVQYF
                     PNERYLEQVLDGVWAMLEPGGRLVLGDIRRARSLRAFQVAVQQAKHGNLPPAQLRSAVE
                     QGLLLEKELVIDPEWFQRWAERAGAAGVDVRLKEGAFQNELTRHRYEIVVHKPGTTE"
     CDS_motif       31991..32026
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0011"
                     /evalue="4.10E+01"
                     /label="C3_starter_134-155"
                     /locus_tag="tioS"
                     /protein_end="1016"
                     /protein_start="1004"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="GAGTGLLLARVA"
     aSDomain        33140..33343
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioS_PCP.1"
                     /evalue="2.20E-27"
                     /label="tioS_PCP.1"
                     /locus_tag="tioS"
                     /protein_end="1455"
                     /protein_start="1387"
                     /score="86.9"
                     /tool="antismash"
                     /translation="EESLCEIFAGVLGLDRVGVDDNFFTIGGHSLLATRVVSRIRAAHG
                     VEIPIRTIFEAPTVAELVAHLTG"
     aSDomain        33386..34285
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioS_Condensation_LCL.2"
                     /domain_subtype="Condensation_LCL"
                     /evalue="5.10E-114"
                     /label="tioS_Condensation_LCL.2"
                     /locus_tag="tioS"
                     /protein_end="1769"
                     /protein_start="1469"
                     /score="372.1"
                     /tool="antismash"
                     /translation="DRLPVSFAQQRLWFIHRFEGPSPTYIIPLSMRLRGKLDVPALRQA
                     VHDVVVRHESLRTVFDEVDGAPYQRVLDPDGLAIPWQEHEVTESALQEALRLEARRPFD
                     LAAEIPVRAALFRVGEHDAVLLLPLHHIAADGWSLGPLAEDLTAAYTARCDGQRPQWAA
                     LPVQYADYTLWQRDLLGGDDPHSLYRRQLDYWTGQLAGLPESLQLPTDRARPAVASFAG
                     EVLPVELDESLTEDLRKLALRTGTTVSMVLQAGLAGLLSKLGAGNDIPIGSPIAGRTDE
                     ALNRLVGFFVNTWVARVDT"
     aSModule        33386..38371
                     /complete
                     /domains="nrpspksdomains_tioS_Condensation_LCL.2"
                     /domains="nrpspksdomains_tioS_AMP-binding.2"
                     /domains="nrpspksdomains_tioS_nMT.2"
                     /domains="nrpspksdomains_tioS_PCP.2"
                     /domains="nrpspksdomains_tioS_Thioesterase.1"
                     /final_module
                     /locus_tags="tioS"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       33401..33433
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0012"
                     /evalue="8.50E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="tioS"
                     /protein_end="1485"
                     /protein_start="1474"
                     /score="8.9"
                     /tool="antismash"
                     /translation="SFAQQRLWFIH"
     CDS_motif       33452..33565
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0013"
                     /evalue="3.00E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="tioS"
                     /protein_end="1529"
                     /protein_start="1491"
                     /score="55.0"
                     /tool="antismash"
                     /translation="PTYIIPLSMRLRGKLDVPALRQAVHDVVVRHESLRTVF"
     CDS_motif       33770..33835
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0014"
                     /evalue="6.40E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="tioS"
                     /protein_end="1619"
                     /protein_start="1597"
                     /score="31.5"
                     /tool="antismash"
                     /translation="LHHIAADGWSLGPLAEDLTAAY"
     CDS_motif       33884..33922
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0015"
                     /evalue="1.20E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="tioS"
                     /protein_end="1648"
                     /protein_start="1635"
                     /score="14.7"
                     /tool="antismash"
                     /translation="QYADYTLWQRDLL"
     CDS_motif       34187..34270
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0016"
                     /evalue="1.40E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="tioS"
                     /protein_end="1764"
                     /protein_start="1736"
                     /score="40.0"
                     /tool="antismash"
                     /translation="DIPIGSPIAGRTDEALNRLVGFFVNTWV"
     CDS_motif       34325..34444
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0017"
                     /evalue="2.80E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="tioS"
                     /protein_end="1822"
                     /protein_start="1782"
                     /score="68.0"
                     /tool="antismash"
                     /translation="REVSLAAYDHQDIPFEHLVEALNPVRSTAHHPLFQVCLAL"
     aSDomain        34796..35944
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioS_AMP-binding.2"
                     /evalue="1.50E-102"
                     /label="tioS_AMP-binding.2"
                     /locus_tag="tioS"
                     /protein_end="2322"
                     /protein_start="1939"
                     /score="335.1"
                     /tool="antismash"
                     /translation="FAAVVAEQPEAVALVAADGEESWTYGELDRWANRIAHHLHARGVG
                     RQHRVALVMERSPLLVAAVLGTLKAGACYVPVEPTWPRARIDLVLADLDPALVIDERLA
                     EEDLTGYPTRPLDTADVGGEHLAYLMYTSGSTGTPKGVEVSHRNVLSLALDPCWADADH
                     QRVLVHAPPTFDASTYEMWVPLLHGGAAVVAPPGKLDAARLATLIAERGVTALWLPAGL
                     FDLITQHHPKSFVQVREVWAGGDVLSPAAVRRLVRDDGTLTVVNGYGPTETTTFAARYR
                     MSAPARCKDPLPIGEPMAGSRLYALDDRLRQVPQGVIGELYVGGDGVARGYANHPPLTS
                     ERFVADPFGRPGERMYRTGDLVRWNHDGQLEFLGRVDEQVKIR"
     CDS_motif       34988..35026
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0018"
                     /evalue="1.70E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="tioS"
                     /protein_end="2016"
                     /protein_start="2003"
                     /score="12.0"
                     /tool="antismash"
                     /translation="LGTLKAGACYVPV"
     CDS_motif       35174..35233
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0019"
                     /evalue="3.90E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="tioS"
                     /protein_end="2085"
                     /protein_start="2065"
                     /score="28.6"
                     /tool="antismash"
                     /translation="AYLMYTSGSTGTPKGVEVSH"
     CDS_motif       35735..35824
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0020"
                     /evalue="5.10E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="tioS"
                     /protein_end="2282"
                     /protein_start="2252"
                     /score="47.5"
                     /tool="antismash"
                     /translation="PQGVIGELYVGGDGVARGYANHPPLTSERF"
     CDS_motif       35909..35971
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0021"
                     /evalue="6.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="tioS"
                     /protein_end="2331"
                     /protein_start="2310"
                     /score="34.3"
                     /tool="antismash"
                     /translation="FLGRVDEQVKIRGFRVEPGEI"
     aSDomain        36221..36880
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioS_nMT.2"
                     /domain_subtype="nMT"
                     /evalue="2.10E-95"
                     /label="tioS_nMT.2"
                     /locus_tag="tioS"
                     /protein_end="2634"
                     /protein_start="2414"
                     /score="311.2"
                     /tool="antismash"
                     /translation="IPLSEMRRWRDSVVEEVRGLRARRILEIGVGSGLLLGPLAPEAEA
                     YWGTDFSLPVIERLEVQVGTDPCLKEKVSLRCQHADVADGLPVKYFDTVILNSVVQYFP
                     DAAYLSRVLDVALDRLAPGGRILVGDVRNYGTLREFLTAVHHAQHPQDSASAVRAAVER
                     AVLAEKELVIDPDFFTEWARTRPDVVAVDIRLKPGADQNELTRHRYEVILHKQPSQP"
     aSDomain        37436..37639
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioS_PCP.2"
                     /evalue="3.60E-25"
                     /label="tioS_PCP.2"
                     /locus_tag="tioS"
                     /protein_end="2887"
                     /protein_start="2819"
                     /score="79.8"
                     /tool="antismash"
                     /translation="EAELAGLFAEVLGVDRVGIEDDFFDCGGSSLQVIRLIWRIRAELG
                     FDIPVRTIFQHPTVAEVAEHLAA"
     aSDomain        37712..38371
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioS_Thioesterase.1"
                     /evalue="2.10E-34"
                     /label="tioS_Thioesterase.1"
                     /locus_tag="tioS"
                     /protein_end="3131"
                     /protein_start="2911"
                     /score="111.7"
                     /tool="antismash"
                     /translation="PIWLVPPGGGLSWAYLGFAQHLDRSRPIYGLQARGFVGDPRATSI
                     ESMVDDYVDQILRVQPEGPYNVLGWSLGGPIAQAVAAELQRRECEVDLLAVLDSGPASY
                     FADFQTPDEKLVRRYLAHYMGHLAGMAEFESLVQTSTTLFIEHTDLMTQFTSPPFRGDL
                     IFFAALIDQGTRERRQLEVELDVQWREYTEGTVRRFDIECAHNEMMWPENAAMISRI"
     CDS_motif       37889..37963
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioS_0022"
                     /evalue="8.70E-12"
                     /label="NRPS-te1"
                     /locus_tag="tioS"
                     /protein_end="2995"
                     /protein_start="2970"
                     /score="37.4"
                     /tool="antismash"
                     /translation="QPEGPYNVLGWSLGGPIAQAVAAEL"
     gene            38449..38664
                     /gene="tioT"
     CDS             38449..38664
                     /codon_start=1
                     /db_xref="InterPro:IPR005153"
                     /db_xref="InterPro:IPR015166"
                     /db_xref="UniProtKB/TrEMBL:Q333U6"
                     /gene="tioT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009:mbtH-like protein (Score: 114.2; E-value:
                     2.8e-35)"
                     /gene_kind="biosynthetic-additional"
                     /product="MbtH homologue"
                     /protein_id="CAJ34376.1"
                     /transl_table=11
                     /translation="MSVNPFDDEDGEFYVLVNDEEQHSLWPTFGDVPDGWRIVFGPAGR
                     AESVAYVEENWTDMRPKSLREAMSAA"
     gene            38642..41266
                     /gene="tioU"
     CDS             38642..41266
                     /codon_start=1
                     /db_xref="GOA:Q333U5"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="UniProtKB/TrEMBL:Q333U5"
                     /function="involved in thiocoraline resistance"
                     /gene="tioU"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 61.5; E-value:
                     1.7e-18)"
                     /gene_kind="transport"
                     /product="DNA excisionase"
                     /protein_id="CAJ34377.1"
                     /transl_table=11
                     /translation="MRRCRQHDVRRGLAGRRVRLRAHDFELPRRRWRKVRTEVFTGCLG
                     IELGCGKPEIAGGVISPGHPAGSASRARHFGGPMTVASPRQSREDLSLVPDTHDVIRVV
                     GARENNLKDIRLEIPKRRLTVFTGVSGSGKSSLVFDTIAAESQRLINETYSAFVQGFMP
                     TLSRPDVDVLDGLTTAIIVSQERIGNNPRSTVGTVTDANAMLRILFSRLGEPRLGSPRS
                     YSFNIPSISVANAVTVGQGSRAVEEQRGFDVAGGMCPRCEGTGSVNDVDLTQLYDATKS
                     LDEGAIRVPGYQVGGYNHRLYAGSGLLDPGKPVEKYTEKELNDFLHREPTRLKIGDYHT
                     NYEGLVARVQKSLLTKDIEALQPHVRAFVERAVTFTACPDCGGTRLNEQARASRIKGIN
                     IADASAMQINDLAEWVRDLAEPSVAPLLATLLHTLDSFVGIGLGYLSLDRASGTLSGGE
                     AQRVKMIRHLGSPLTDVTYVFDEPTIGLHPHDIQRMNKLLLRLRDKGNTVLVVEHKPET
                     IAIADRVVDLGPGAGTAGGTICFEGTVAELRSADTLTGRHLDDKASLKDRVRTPSGSLE
                     VRGASKHNLRDVDVDIPLGVLVVVTGVAGSGKSSLIEGSVSGRDGVVTIDQGSIKGSRR
                     SNPATYTGLLDPIRKAFAKANGVKPALFSSNSEGACATCKGAGVIYTDLAIMAGAATTC
                     DDCEGRRFQDFVLQYRLGGRDISEVLAMSVAEAGRFFAAGQARTPAAVVILERLADVGL
                     GYLSLGQPLPTLSGGERQRLKLAAHLADEGGIVVLDEPTTGLHLADVEQLLGLLDRLVD
                     AGRSVMVIEHHQAVMAHADWIIDLGPAAGHDGGRVVFEGCPADLVASRATLTGEHLAAY
                     VGV"
     gene            41835..42371
                     /gene="tioV"
     CDS             41835..42371
                     /codon_start=1
                     /db_xref="GOA:Q333U4"
                     /db_xref="InterPro:IPR001867"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="InterPro:IPR016032"
                     /db_xref="UniProtKB/TrEMBL:Q333U4"
                     /gene="tioV"
                     /product="OmpR family regulator"
                     /protein_id="CAJ34378.1"
                     /transl_table=11
                     /translation="MGGRNSDVVFIRWPAQADLRTRCRKEGVPRLLVVEGGAQPPISND
                     PVEDWVRPPVSRNDLEARVKALQQRFNSRRLPTIDSTGTLTFGRHSIVISNTQAELMRL
                     LIERFGEVVYRIEFVQCLAIRTPALNRNSLDLHIMRLRRRLLPIDLAIRTVWGRGYMLA
                     YAASAEAIIRNASGM"
     gene            complement(42392..43255)
                     /gene="tioW"
     CDS             complement(42392..43255)
                     /codon_start=1
                     /db_xref="InterPro:IPR003737"
                     /db_xref="UniProtKB/TrEMBL:Q333U3"
                     /gene="tioW"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /product="putative regulator"
                     /protein_id="CAJ34379.1"
                     /sec_met_domain="PIG-L (E-value: 6.5e-26, bitscore: 82.9,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADALSSRPCSTAAIKRDHIMLSSHTVIVLHAHPDDEAIFTGLTM
                     RRLADAGARVILVMATDGAAGVPHVPLSRGESLRSRRLAELERACDLLGVARLEVLGYA
                     DSGAHGGPYRAGTLGAASATRVARQVARIASREGATTLVHYDPGGIYRHVDHVQVHRVG
                     ALVTRSLQLAGYQATVDASALRAGPRHVLQRAAGDLTDMGVPASRISLAVDAEGADLLA
                     KMAAMATHASQVGAADLDPSCFAAAYGREWFVREGRLGALDALLAASAGPAVATHRNLQ
                     LDGTAI"
     gene            complement(43337..43741)
                     /gene="tioX"
     CDS             complement(43337..43741)
                     /codon_start=1
                     /db_xref="InterPro:IPR004360"
                     /db_xref="PDB:3ITW"
                     /db_xref="UniProtKB/TrEMBL:Q333U2"
                     /gene="tioX"
                     /product="hypothetical protein"
                     /protein_id="CAJ34380.1"
                     /transl_table=11
                     /translation="MVVELAYTDPDRAVDWLVRVFGFRLLLRQPAIGTIRHADLDTGGG
                     IVMVRRTGEPYTVSCAGGHTCKQVIVWVSDVDEHFMRSTAAGADIVQPLQDKPWGLRQY
                     LVRDLEGHLWEFTRHLRDVPPREWGAVAMT"
     gene            44152..49566
                     /gene="tioY"
     CDS             44152..49566
                     /NRPS_PKS="Domain: AMP-binding (120-513). E-value:
                     8.4e-100. Score: 326.0. Matches aSDomain:
                     nrpspksdomains_tioY_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (623-691). E-value: 2.9e-21. Score:
                     67.3. Matches aSDomain: nrpspksdomains_tioY_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (746-1046). E-value:
                     2.7e-106. Score: 346.8. Matches aSDomain:
                     nrpspksdomains_tioY_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1210-1599). E-value:
                     2.2e-106. Score: 347.7. Matches aSDomain:
                     nrpspksdomains_tioY_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1705-1773). E-value: 1.1e-19.
                     Score: 62.2. Matches aSDomain: nrpspksdomains_tioY_PCP.2"
                     /codon_start=1
                     /db_xref="GOA:Q333U1"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="UniProtKB/TrEMBL:Q333U1"
                     /gene="tioY"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     368.9; E-value: 5.5e-112)"
                     /gene_kind="biosynthetic"
                     /product="NRPS protein"
                     /protein_id="CAJ34381.1"
                     /sec_met_domain="Condensation (E-value: 2.3e-76, bitscore:
                     248.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.1e-117, bitscore:
                     382.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-14, bitscore:
                     45.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLQLLGSATQSTEPNLPGLTVTSLDANPGGHPFDLSITCTESPD
                     QLRLVADYSVDLFDEPRMARLLRHLERVLRTAVDAPDTPLSALPLLDEEEQTLLLHTWQ
                     GPQGERAREPVHVQIARLAAERPDLVAATLHGAELTYGELDRRAGVLAHRFRALGVGRD
                     DIVALLLERGFDLIVGMVAAQKAGGAFVVMDPGHPVRRIEFILEDTAAKAVVTRSALAD
                     RLPEGAAATPVLVDTEWDELSAAAAGAAPLDELADENSLAYVLYTSGSTGKPKGVMIEH
                     HALNTFLLWLGNIFDFGPGDRLLQHMAPIFDFAEGEIFTALTRGVTMVFVPEEHRTDPD
                     VIGQLLVSERITYIGGPPAILGRIPPGSYPDLKYMIAGGEAVTGDLINRWNTPGRRFIN
                     GYGPTEAAVGCIFYECEHRTWIGQPPIGRAMPNRVAYVLDRWNNLQPVGVPGEVITGGE
                     GLARGYLNRPELTAEKFIDNPYRPGERMYRTGDLGVWTEDGQIQFLGRIDTQVKLNGLR
                     IELEEIESTLTAHPGVAEAAVALREDSPGSKRLVGYVVPAGAAAPPTEELREHLLADLP
                     PYMVPHVFVALDVLPLTSVGKVDRNRLPVPEETGSAEVELVAPRTPEEERVAEIFAAVL
                     GVERVGADANFFELGGNSLMAARVLSRIAELGGASATMRDFYTKPRVSEIAQLLAGTPS
                     STDPATPTDAAPVADQTRARLEQEIADLEQRLRAARAALAGQDGPVSGGHEGQRLPLSP
                     TQEQLWFLEQLAPGQPTYHIPVPVRLTGPLDVDLLGRALTAVVARHEALRTTFGTDDDT
                     PYQLVSPAGEVPLPVHELDATAADDREQALRVELERDATEPFDLGRDLMLRARLIRLDG
                     QEHVLSMVLHHICADGWSAGLLVRDLAELYDALRHDRQPQLPALRLQYADHALAQRRQL
                     DAGDLESQLAYWARQLADAPILDLPSDRPRPATATNRGALLVRRMPADVLEGLRRVAQQ
                     EQASTYAVLLAGFKTVLMRYTGVDDVVVGTAGAGRGRPELEDLVGFFVNMLALRTDLSG
                     DPSFGEAVRRTMGTLLAAWDHQDAPFERVVGRLGRRRDASRNPVFQVSIDLLSGDLVDF
                     RFPGLAAEFLDVDPGVSRFDMAINAYEETDGITFRIEYATDLFDTARIEAMFGHLERVL
                     RAAVAAPQTPLSALPLLDDTERTELLALAQGKRRPHRPATLPELFAASVARTPQATAVI
                     AAEGTLSYAELDERSRRLAARLRAAGVGTGDVVPVLLERSLAEVVSVLAVLRAGAAYAP
                     MDPAAPPSRLAFQVRDTGARVVVGDPTRLDTVVGVTIVDPAAELPEAADEPWLAELTPA
                     SLAYVLYTSGSTGEPKGVLIEHGMVAGYLEWMVPDFGVEPRSRMMHCCAPVFDLAVGEL
                     FGALTAGATVVVAGHDDVHRPGALTALARETGATHIFTTPTVLGLLDPAELPQLRSVMM
                     AGEPAPPSLVAAWHVDGRRVLNLYGPAETTVGCTWYECPAGTAPAATVPIGRPMPNRRV
                     YVVDDSGDLAPVGVPGELVVAGNGVARGYLDRPELTASAFGADERAGEGRAYRTGDLAR
                     WNRDGQLEFLGRRDGQVKLRGLRVELGEVEHALRTAAGVSGAAAAVHGTGAEAVLVGYV
                     VGELSDDDAEALRTTLAGKLPGYMVPNVVLRLPQLPLTRTGKVDRKRLPAPESGAGQAA
                     YVPPGTDDERLIAGVFADLLGLERAGREDEFFLSGGNSLQAIRAVGRLNDALGVPLTVR
                     DFYAAPTVAALAELAGRRRAAEQAAQWQLLDEIEQLSDDEVERLLAAD"
     aSDomain        44512..45690
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioY_AMP-binding.1"
                     /evalue="8.40E-100"
                     /label="tioY_AMP-binding.1"
                     /locus_tag="tioY"
                     /protein_end="513"
                     /protein_start="120"
                     /score="326.0"
                     /tool="antismash"
                     /translation="RLAAERPDLVAATLHGAELTYGELDRRAGVLAHRFRALGVGRDDI
                     VALLLERGFDLIVGMVAAQKAGGAFVVMDPGHPVRRIEFILEDTAAKAVVTRSALADRL
                     PEGAAATPVLVDTEWDELSAAAAGAAPLDELADENSLAYVLYTSGSTGKPKGVMIEHHA
                     LNTFLLWLGNIFDFGPGDRLLQHMAPIFDFAEGEIFTALTRGVTMVFVPEEHRTDPDVI
                     GQLLVSERITYIGGPPAILGRIPPGSYPDLKYMIAGGEAVTGDLINRWNTPGRRFINGY
                     GPTEAAVGCIFYECEHRTWIGQPPIGRAMPNRVAYVLDRWNNLQPVGVPGEVITGGEGL
                     ARGYLNRPELTAEKFIDNPYRPGERMYRTGDLGVWTEDGQIQFLGRIDTQVKL"
     aSModule        44512..46224
                     /complete
                     /domains="nrpspksdomains_tioY_AMP-binding.1"
                     /domains="nrpspksdomains_tioY_PCP.1"
                     /locus_tags="tioY"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       44935..44994
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0001"
                     /evalue="2.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="tioY"
                     /protein_end="281"
                     /protein_start="261"
                     /score="35.3"
                     /tool="antismash"
                     /translation="AYVLYTSGSTGKPKGVMIEH"
     CDS_motif       45352..45375
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0002"
                     /evalue="2.80E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="tioY"
                     /protein_end="408"
                     /protein_start="400"
                     /score="4.7"
                     /tool="antismash"
                     /translation="YGPTEAAV"
     CDS_motif       45487..45576
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0003"
                     /evalue="7.20E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="tioY"
                     /protein_end="475"
                     /protein_start="445"
                     /score="50.3"
                     /tool="antismash"
                     /translation="PVGVPGEVITGGEGLARGYLNRPELTAEKF"
     CDS_motif       45658..45723
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0004"
                     /evalue="6.90E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="tioY"
                     /protein_end="524"
                     /protein_start="502"
                     /score="31.1"
                     /tool="antismash"
                     /translation="FLGRIDTQVKLNGLRIELEEIE"
     CDS_motif       45763..45816
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0005"
                     /evalue="1.50E+00"
                     /label="C5_LCL_267-296"
                     /locus_tag="tioY"
                     /protein_end="555"
                     /protein_start="537"
                     /score="1.5"
                     /tool="antismash"
                     /translation="VALREDSPGSKRLVGYVV"
     CDS_motif       45937..45963
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0006"
                     /evalue="9.10E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="tioY"
                     /protein_end="604"
                     /protein_start="595"
                     /score="3.1"
                     /tool="antismash"
                     /translation="GKVDRNRLP"
     aSDomain        46021..46224
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioY_PCP.1"
                     /evalue="2.90E-21"
                     /label="tioY_PCP.1"
                     /locus_tag="tioY"
                     /protein_end="691"
                     /protein_start="623"
                     /score="67.3"
                     /tool="antismash"
                     /translation="EERVAEIFAAVLGVERVGADANFFELGGNSLMAARVLSRIAELGG
                     ASATMRDFYTKPRVSEIAQLLAG"
     aSDomain        46390..47289
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioY_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.70E-106"
                     /label="tioY_Condensation_LCL.1"
                     /locus_tag="tioY"
                     /protein_end="1046"
                     /protein_start="746"
                     /score="346.8"
                     /tool="antismash"
                     /translation="QRLPLSPTQEQLWFLEQLAPGQPTYHIPVPVRLTGPLDVDLLGRA
                     LTAVVARHEALRTTFGTDDDTPYQLVSPAGEVPLPVHELDATAADDREQALRVELERDA
                     TEPFDLGRDLMLRARLIRLDGQEHVLSMVLHHICADGWSAGLLVRDLAELYDALRHDRQ
                     PQLPALRLQYADHALAQRRQLDAGDLESQLAYWARQLADAPILDLPSDRPRPATATNRG
                     ALLVRRMPADVLEGLRRVAQQEQASTYAVLLAGFKTVLMRYTGVDDVVVGTAGAGRGRP
                     ELEDLVGFFVNMLALRTDL"
     aSModule        46390..49470
                     /complete
                     /domains="nrpspksdomains_tioY_Condensation_LCL.1"
                     /domains="nrpspksdomains_tioY_AMP-binding.2"
                     /domains="nrpspksdomains_tioY_PCP.2"
                     /locus_tags="tioY"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       46456..46569
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0007"
                     /evalue="1.30E-19"
                     /label="C2_LCL_024-062"
                     /locus_tag="tioY"
                     /protein_end="806"
                     /protein_start="768"
                     /score="62.6"
                     /tool="antismash"
                     /translation="PTYHIPVPVRLTGPLDVDLLGRALTAVVARHEALRTTF"
     CDS_motif       46789..46854
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0008"
                     /evalue="7.90E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="tioY"
                     /protein_end="901"
                     /protein_start="879"
                     /score="34.4"
                     /tool="antismash"
                     /translation="LHHICADGWSAGLLVRDLAELY"
     CDS_motif       47191..47280
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0009"
                     /evalue="1.30E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="tioY"
                     /protein_end="1043"
                     /protein_start="1013"
                     /score="46.5"
                     /tool="antismash"
                     /translation="DVVVGTAGAGRGRPELEDLVGFFVNMLALR"
     CDS_motif       47335..47439
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0010"
                     /evalue="4.00E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="tioY"
                     /protein_end="1096"
                     /protein_start="1061"
                     /score="48.1"
                     /tool="antismash"
                     /translation="TLLAAWDHQDAPFERVVGRLGRRRDASRNPVFQVS"
     aSDomain        47782..48948
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioY_AMP-binding.2"
                     /evalue="2.20E-106"
                     /label="tioY_AMP-binding.2"
                     /locus_tag="tioY"
                     /protein_end="1599"
                     /protein_start="1210"
                     /score="347.7"
                     /tool="antismash"
                     /translation="FAASVARTPQATAVIAAEGTLSYAELDERSRRLAARLRAAGVGTG
                     DVVPVLLERSLAEVVSVLAVLRAGAAYAPMDPAAPPSRLAFQVRDTGARVVVGDPTRLD
                     TVVGVTIVDPAAELPEAADEPWLAELTPASLAYVLYTSGSTGEPKGVLIEHGMVAGYLE
                     WMVPDFGVEPRSRMMHCCAPVFDLAVGELFGALTAGATVVVAGHDDVHRPGALTALARE
                     TGATHIFTTPTVLGLLDPAELPQLRSVMMAGEPAPPSLVAAWHVDGRRVLNLYGPAETT
                     VGCTWYECPAGTAPAATVPIGRPMPNRRVYVVDDSGDLAPVGVPGELVVAGNGVARGYL
                     DRPELTASAFGADERAGEGRAYRTGDLARWNRDGQLEFLGRRDGQVKLR"
     CDS_motif       47911..47973
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0011"
                     /evalue="9.60E-01"
                     /label="C2_DCL_024-062"
                     /locus_tag="tioY"
                     /protein_end="1274"
                     /protein_start="1253"
                     /score="1.8"
                     /tool="antismash"
                     /translation="TGDVVPVLLERSLAEVVSVLA"
     CDS_motif       48187..48246
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0012"
                     /evalue="1.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="tioY"
                     /protein_end="1365"
                     /protein_start="1345"
                     /score="32.8"
                     /tool="antismash"
                     /translation="AYVLYTSGSTGEPKGVLIEH"
     CDS_motif       48604..48627
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0013"
                     /evalue="2.10E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="tioY"
                     /protein_end="1492"
                     /protein_start="1484"
                     /score="5.0"
                     /tool="antismash"
                     /translation="YGPAETTV"
     CDS_motif       48742..48831
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0014"
                     /evalue="3.60E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="tioY"
                     /protein_end="1560"
                     /protein_start="1530"
                     /score="51.2"
                     /tool="antismash"
                     /translation="PVGVPGELVVAGNGVARGYLDRPELTASAF"
     CDS_motif       48913..48978
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0015"
                     /evalue="3.00E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="tioY"
                     /protein_end="1609"
                     /protein_start="1587"
                     /score="32.2"
                     /tool="antismash"
                     /translation="FLGRRDGQVKLRGLRVELGEVE"
     CDS_motif       49186..49212
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioY_0016"
                     /evalue="3.00E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="tioY"
                     /protein_end="1687"
                     /protein_start="1678"
                     /score="4.4"
                     /tool="antismash"
                     /translation="GKVDRKRLP"
     aSDomain        49267..49470
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioY_PCP.2"
                     /evalue="1.10E-19"
                     /label="tioY_PCP.2"
                     /locus_tag="tioY"
                     /protein_end="1773"
                     /protein_start="1705"
                     /score="62.2"
                     /tool="antismash"
                     /translation="ERLIAGVFADLLGLERAGREDEFFLSGGNSLQAIRAVGRLNDALG
                     VPLTVRDFYAAPTVAALAELAGR"
     gene            49635..53672
                     /gene="tioZ"
     CDS             49635..53672
                     /NRPS_PKS="Domain: Condensation_LCL (42-343). E-value:
                     5.3e-102. Score: 332.7. Matches aSDomain:
                     nrpspksdomains_tioZ_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (509-902). E-value:
                     5.3e-100. Score: 326.7. Matches aSDomain:
                     nrpspksdomains_tioZ_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1009-1077). E-value: 6.3e-23.
                     Score: 72.6. Matches aSDomain: nrpspksdomains_tioZ_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1096-1337). E-value:
                     2.7e-30. Score: 98.3. Matches aSDomain:
                     nrpspksdomains_tioZ_Thioesterase.1"
                     /codon_start=1
                     /db_xref="GOA:Q333U0"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001031"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="UniProtKB/TrEMBL:Q333U0"
                     /gene="tioZ"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 368;
                     E-value: 1e-111)"
                     /gene_kind="biosynthetic"
                     /product="NRPS protein"
                     /protein_id="CAJ34382.1"
                     /sec_met_domain="Condensation (E-value: 5.1e-77, bitscore:
                     250.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-111, bitscore:
                     363.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.8e-16, bitscore:
                     50.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDETFDGRVARLDERRRLLLERMRQQRRQPPATIGARPAGDERV
                     PLSRAQEQLWFLAQLAPAEPTYNLVQASYLTGEVDPAALRRALDGVVAQHEALRTVVES
                     VDGVAYQRVLPPGPASLVVDDVSRLPEEQRRPAALTLLQQQEVHRPFDLATGPLFRARL
                     VRLGPTEHALAVAAHHIVVDGWSMGLILRELAAAYDADRHGTRARLDPPALQYPDFARW
                     QHQQLATAELDNHLRYWAQRLADLPTLELPADRPRPTTASFRGALLEQPLDPQLHAGVQ
                     ALAKETGASPFMVLVAAFAAMLARYTGTDDLAVGTTFSGRSRPELESVVGFFANMGVLR
                     LDTSGDPSFATLVDRARDTCLGAWEHQDAPFERVVQRLAPPRDPGRNPLFQVAVQLLDG
                     STWGGPTLPGTDSTPVDLRLDRSRFDMMVSLVDHGDRYSVLTEYSTDLFDARRVRAMLD
                     HVARLLDAGLADPATTLSRLPMLDPAERERVLALGAGERRDVAPATVHQLVRAQAERNP
                     DAVAVRHGDHELTYRELLDRAARRAAGLRDAGLRPGDRVPALLDRGVDEVLTPMAIWHA
                     GGVYVPLDTAAPPNRLRRILTNCAARLVLTRTEHAAGVPEGPWRTLLLDTGDLDSAAGL
                     APEPSTGPDDLAYVLHTSGTTGDPKGVQLPHRGFVTYLDWMRDQWRCGPGDRVLHGCAP
                     VFDLAAGEVLAALTSGATVVVIGKDRLLSPGGLAEVLAAERITHLFLTPTTLGLVEDDT
                     DRFDALREVLVGGEVCPADLVARWARPGRRRFVNLYGPTEATVGCLAHDCTDWSAATPP
                     PIGATMPNRRTYLVDRWDNPVPVGVPGEILVGGAALSTGYLNDDELTGRRFTADPFDPQ
                     GRVYRTGDRGHWDAQGRLHFGGRLDGQVKLRGLRVELDEIEALLSRHSGVARAAVTVVR
                     DGNGVQRLVGYVVDAAEPASDADLRTHLSTELPAHLVPGRFVRLPALPLTTSGKVNRRA
                     LPAPEAADTDDTGAAPTTGAERQVAEIFAEVLGVARVGAETSFFDLGGHSLQAAHVLAR
                     IAGRIGTSVSLKQFYATPTVRAVARFVEHGPVVDASPLVTLKATGSRPRLYCPHAVSGS
                     PYWYLPLSRALHPEQPVDGFEAPGLEGGIEPVDDLVTLAGRYVGALRERQPHGPYLLAG
                     WSMGGFLCFEMARQLAAVGAAPDLVVMIDSNEPGPLPLPSERQVMETFVADLAGLSAAP
                     APPLDAEVVDAADPIAALTGFLVRHGLIPSDVRADFVANRYAVFRANMRAIYGYQPAPY
                     AGRTVLVQAEREASRAAWRRWSPAMEVVTLPGDHYSMWSPQHLPALAALIDDQVARVLD
                     LG"
     aSDomain        49761..50663
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioZ_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="5.30E-102"
                     /label="tioZ_Condensation_LCL.1"
                     /locus_tag="tioZ"
                     /protein_end="343"
                     /protein_start="42"
                     /score="332.7"
                     /tool="antismash"
                     /translation="ERVPLSRAQEQLWFLAQLAPAEPTYNLVQASYLTGEVDPAALRRA
                     LDGVVAQHEALRTVVESVDGVAYQRVLPPGPASLVVDDVSRLPEEQRRPAALTLLQQQE
                     VHRPFDLATGPLFRARLVRLGPTEHALAVAAHHIVVDGWSMGLILRELAAAYDADRHGT
                     RARLDPPALQYPDFARWQHQQLATAELDNHLRYWAQRLADLPTLELPADRPRPTTASFR
                     GALLEQPLDPQLHAGVQALAKETGASPFMVLVAAFAAMLARYTGTDDLAVGTTFSGRSR
                     PELESVVGFFANMGVLRLDT"
     aSModule        49761..53645
                     /complete
                     /domains="nrpspksdomains_tioZ_Condensation_LCL.1"
                     /domains="nrpspksdomains_tioZ_AMP-binding.1"
                     /domains="nrpspksdomains_tioZ_PCP.1"
                     /domains="nrpspksdomains_tioZ_Thioesterase.1"
                     /final_module
                     /locus_tags="tioZ"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       49827..49937
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioZ_0001"
                     /evalue="1.60E-13"
                     /label="C2_LCL_024-062"
                     /locus_tag="tioZ"
                     /protein_end="101"
                     /protein_start="64"
                     /score="43.0"
                     /tool="antismash"
                     /translation="PTYNLVQASYLTGEVDPAALRRALDGVVAQHEALRTV"
     CDS_motif       50166..50228
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioZ_0002"
                     /evalue="3.30E-12"
                     /label="C3_DCL_135-156"
                     /locus_tag="tioZ"
                     /protein_end="198"
                     /protein_start="177"
                     /score="38.7"
                     /tool="antismash"
                     /translation="HHIVVDGWSMGLILRELAAAY"
     CDS_motif       50277..50315
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioZ_0003"
                     /evalue="1.10E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="tioZ"
                     /protein_end="227"
                     /protein_start="214"
                     /score="14.8"
                     /tool="antismash"
                     /translation="QYPDFARWQHQQL"
     CDS_motif       50565..50654
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioZ_0004"
                     /evalue="9.80E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="tioZ"
                     /protein_end="340"
                     /protein_start="310"
                     /score="40.5"
                     /tool="antismash"
                     /translation="DLAVGTTFSGRSRPELESVVGFFANMGVLR"
     CDS_motif       50703..50819
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioZ_0005"
                     /evalue="3.80E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="tioZ"
                     /protein_end="395"
                     /protein_start="356"
                     /score="70.7"
                     /tool="antismash"
                     /translation="RDTCLGAWEHQDAPFERVVQRLAPPRDPGRNPLFQVAVQ"
     aSDomain        51162..52340
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioZ_AMP-binding.1"
                     /evalue="5.30E-100"
                     /label="tioZ_AMP-binding.1"
                     /locus_tag="tioZ"
                     /protein_end="902"
                     /protein_start="509"
                     /score="326.7"
                     /tool="antismash"
                     /translation="RAQAERNPDAVAVRHGDHELTYRELLDRAARRAAGLRDAGLRPGD
                     RVPALLDRGVDEVLTPMAIWHAGGVYVPLDTAAPPNRLRRILTNCAARLVLTRTEHAAG
                     VPEGPWRTLLLDTGDLDSAAGLAPEPSTGPDDLAYVLHTSGTTGDPKGVQLPHRGFVTY
                     LDWMRDQWRCGPGDRVLHGCAPVFDLAAGEVLAALTSGATVVVIGKDRLLSPGGLAEVL
                     AAERITHLFLTPTTLGLVEDDTDRFDALREVLVGGEVCPADLVARWARPGRRRFVNLYG
                     PTEATVGCLAHDCTDWSAATPPPIGATMPNRRTYLVDRWDNPVPVGVPGEILVGGAALS
                     TGYLNDDELTGRRFTADPFDPQGRVYRTGDRGHWDAQGRLHFGGRLDGQVKLR"
     CDS_motif       51345..51386
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioZ_0006"
                     /evalue="1.20E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="tioZ"
                     /protein_end="584"
                     /protein_start="570"
                     /score="15.4"
                     /tool="antismash"
                     /translation="MAIWHAGGVYVPLD"
     CDS_motif       51573..51632
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioZ_0007"
                     /evalue="7.80E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="tioZ"
                     /protein_end="666"
                     /protein_start="646"
                     /score="24.6"
                     /tool="antismash"
                     /translation="AYVLHTSGTTGDPKGVQLPH"
     CDS_motif       51744..51782
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioZ_0008"
                     /evalue="2.40E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="tioZ"
                     /protein_end="716"
                     /protein_start="703"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="LAALTSGATVVVI"
     CDS_motif       52134..52223
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioZ_0009"
                     /evalue="9.30E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="tioZ"
                     /protein_end="863"
                     /protein_start="833"
                     /score="40.4"
                     /tool="antismash"
                     /translation="PVGVPGEILVGGAALSTGYLNDDELTGRRF"
     CDS_motif       52311..52370
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioZ_0010"
                     /evalue="1.10E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="tioZ"
                     /protein_end="912"
                     /protein_start="892"
                     /score="27.4"
                     /tool="antismash"
                     /translation="GRLDGQVKLRGLRVELDEIE"
     aSDomain        52662..52865
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioZ_PCP.1"
                     /evalue="6.30E-23"
                     /label="tioZ_PCP.1"
                     /locus_tag="tioZ"
                     /protein_end="1077"
                     /protein_start="1009"
                     /score="72.6"
                     /tool="antismash"
                     /translation="ERQVAEIFAEVLGVARVGAETSFFDLGGHSLQAAHVLARIAGRIG
                     TSVSLKQFYATPTVRAVARFVEH"
     aSDomain        52923..53645
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tioZ_Thioesterase.1"
                     /evalue="2.70E-30"
                     /label="tioZ_Thioesterase.1"
                     /locus_tag="tioZ"
                     /protein_end="1337"
                     /protein_start="1096"
                     /score="98.3"
                     /tool="antismash"
                     /translation="RLYCPHAVSGSPYWYLPLSRALHPEQPVDGFEAPGLEGGIEPVDD
                     LVTLAGRYVGALRERQPHGPYLLAGWSMGGFLCFEMARQLAAVGAAPDLVVMIDSNEPG
                     PLPLPSERQVMETFVADLAGLSAAPAPPLDAEVVDAADPIAALTGFLVRHGLIPSDVRA
                     DFVANRYAVFRANMRAIYGYQPAPYAGRTVLVQAEREASRAAWRRWSPAMEVVTLPGDH
                     YSMWSPQHLPALAALIDDQ"
     CDS_motif       53103..53177
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tioZ_0011"
                     /evalue="9.70E-15"
                     /label="NRPS-te1"
                     /locus_tag="tioZ"
                     /protein_end="1181"
                     /protein_start="1156"
                     /score="46.8"
                     /tool="antismash"
                     /translation="QPHGPYLLAGWSMGGFLCFEMARQL"
     CDS             complement(53746..55305)
                     /codon_start=1
                     /db_xref="GOA:Q333T9"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="UniProtKB/TrEMBL:Q333T9"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 294.6; E-value:
                     1.7e-89)"
                     /gene_kind="transport"
                     /note="ORF3"
                     /product="putative permease for glucides"
                     /protein_id="CAJ34383.1"
                     /transl_table=11
                     /translation="MATEDEGRPRGARLVLLILLVAQVMATMDNSIVAVATKTIKDDLQ
                     TSGAVLQLILSGYTLMFAVLVVTGARLGGDVGHRRLFMIGLTGFTASSLLCGIAPTAGT
                     LVAARLLQGAFGAMMVPQVLSVIQIVFTGSARARAIGLYSMVLALGVAAGQIAGGVIVS
                     ADVLGSGWRAAFLVNVPIGLALLAAAPRYLPGHTPSSRFRPDIVGILLLAVSMGAVVAP
                     LVFGREQGWPAWALASIAAGTAGLVLFVRYELRLGARGGQPVLEIDALRPRGVKSGLLA
                     CCILNFAFAGVLFPLTLHVQNGLGYTPLQAGLMFIPYPVGFAAVSLTWTRLPKRFHRPL
                     PVAGLLVFALALAALAVVVAGGWPIAVVSALLLLAGAGMAAGFSTLVEQTAATVGPRYA
                     AALSALVSTGTLLASVVSVVVVGGVYLATAENDPSRSALGLSRSLWVDAGLLMLGFLLA
                     YRTWRLSTRVSAETAPSGDAAEQVEAVAAPGNAPPGEVDVEPATGPVEESSAPTGARSA
                     PR"
     CDS             complement(55381..57222)
                     /codon_start=1
                     /db_xref="GOA:Q333T8"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="UniProtKB/TrEMBL:Q333T8"
                     /gene_functions="transport (smcogs) SMCOG1169:sugar
                     transport protein (Score: 288; E-value: 2e-87)"
                     /gene_kind="transport"
                     /note="ORF4"
                     /product="putative permease for glucides"
                     /protein_id="CAJ34384.1"
                     /transl_table=11
                     /translation="MSESRTADTASAKRRGTLGFLLGVALVTAGVLFQLPDVKMMIDHA
                     RMGSAEPGMDGMDDMDDMDSMPGMEGMSPGEPMDMWTPTMILGMLLLVVGLVVAGRALF
                     AGVRRPDSASVTVESIEHGRLRPAYWITCAVLTIALVVDIMKPLTLGFVMPGMSDEYGM
                     SLESVSILPLVALTGTAVGSVVWGLLGDRYGRRTALLLATLLFIATSACGAMPTFEWNL
                     VMCFTMGTSAGGLLPLVFTLIAELTPRRHRGWVAVTVGGIGGLGGYLAASEAARHLEPA
                     LTWRALWLIGLPSGLLLLLMAPLIPESPLYLLRAGRRTEAEAVLRRYGSHLGATPPAAD
                     TAAAATRPGVGAMLRAYPVVTSVIGVVGVVWGLVNFGFLVMLPAQLREAGLAGGVASGL
                     LADSALYSTPALALVVLLYAAWSGRRALALFIAITAVGLGGVALWTTDSGGTVLLLASI
                     GLLVLSLSAVNAMLLPYSAEIYPTAMRATGSGFAGAATKVGGILGPSAMLLILSLGGGL
                     VAPAIALGVLCLAATVLLLVFGPELGASVGPLARRGVGTVPVSRTGPAPGTGPTDTESP
                     ASVAWSATGNVVPATRPAVSDDDDPRDARTPATPSRT"
     CDS             57895..58470
                     /codon_start=1
                     /db_xref="GOA:Q333T7"
                     /db_xref="InterPro:IPR000835"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="InterPro:IPR023187"
                     /db_xref="UniProtKB/TrEMBL:Q333T7"
                     /gene_functions="regulatory (smcogs) SMCOG1135:MarR family
                     transcriptional regulator (Score: 89.4; E-value: 2.5e-27)"
                     /gene_kind="regulatory"
                     /note="ORF5"
                     /product="putative MarR family regulator"
                     /protein_id="CAJ34385.1"
                     /transl_table=11
                     /translation="MPHVDRSARSGPCCASMDYMTIQSDPMASTDEVRGEPADEFVGAL
                     VSLSRVMVAVAMRTLARIDADVTLQQFRTLVVLVPGPQRVIDLAKLLGVQSSTATRMCD
                     RLVRKGLVARHERVADRRAAWVGLTVAGKELVGLGMRARQQELERMLADLRPDDTDVTT
                     GALVAVLRATGELTDGAWWRQWADSVVE"
     CDS             complement(58532..59206)
                     /codon_start=1
                     /db_xref="InterPro:IPR002645"
                     /db_xref="UniProtKB/TrEMBL:Q333T6"
                     /note="ORF6"
                     /product="putative anti-sigma factor"
                     /protein_id="CAJ34386.1"
                     /transl_table=11
                     /translation="MTVVPDDNLMTLICDVCGDTTTGTACVLPDAEVVWTLVSDHGWSG
                     SPFATGPHRCPRCSALPPGSSLGDGDRAGSGLAEAAVVVPADGGDQDTGDALRAALRGA
                     FDVAGTVVVDLTQVQVIDSLGLGMLVRAHRDVRERGGRLCLAAPSRFIRTVLHTMKLDG
                     VFPIFDSLDAALDQLRNAASQDAVSAGVSPVDVTPSDLPRPAAEVPSMPMARRRAASRV
                     TV"
     CDS             complement(59295..59564)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q333T5"
                     /note="ORF7"
                     /product="hypothetical protein"
                     /protein_id="CAJ34387.1"
                     /transl_table=11
                     /translation="MTSAGIVTALAVGLAVGALGRLVLPGRPAAPLWLTMTIGAVASLL
                     GAITAWLAGVQGFSILGLVVQAGLAAVAVVIVVATTGKERSDSL"
     CDS             complement(59608..60114)
                     /codon_start=1
                     /db_xref="InterPro:IPR002645"
                     /db_xref="UniProtKB/TrEMBL:Q333T4"
                     /note="ORF8"
                     /product="putative anti-sigma factor"
                     /protein_id="CAJ34388.1"
                     /transl_table=11
                     /translation="MAANPAGQGESHSETAGEGALAVTAPRRPECSVPLVEVSITEFDL
                     SCLPETGAVLDQLLALRPGQVVIDLAGCRHIDAAAIGLLLDVHRRMVRAGGVLAVRNPN
                     PRITRILQTARLDQILPVHTDAASAPVTEAVTAAPGVPPADGTPAPGTVPRAAAYGRAA
                     VTVRT"
     CDS             60202..60891
                     /codon_start=1
                     /db_xref="GOA:Q333T3"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR001867"
                     /db_xref="InterPro:IPR011006"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="InterPro:IPR016032"
                     /db_xref="UniProtKB/TrEMBL:Q333T3"
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 209.7; E-value: 6.7e-64)"
                     /gene_kind="regulatory"
                     /note="ORF9"
                     /product="putative response regulator"
                     /protein_id="CAJ34389.1"
                     /transl_table=11
                     /translation="MTAVLVIEDDDRIRLALLLALEDEGYEARGAATAEEGLRTQRRDP
                     ADYVLVDLMLPGIDGFEGIRQLRRDDDVPIVVVSARDDTHDIVAALEAGADDYVVKPVA
                     IKELTARLRALRRRGRTTTASDGPQPVPVLAFGDLEVSPEAGEVRRAGEPVAVTRTEFR
                     LLCELAEHAGRVLSRQQLLSRVWGYDSGDERLVDVHVGRLRQKIEADPANPRHLVTLRG
                     LGYKLQR"
     CDS             60960..62243
                     /codon_start=1
                     /db_xref="GOA:Q333T2"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR003660"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR005467"
                     /db_xref="InterPro:IPR009082"
                     /db_xref="UniProtKB/TrEMBL:Q333T2"
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 214.6; E-value: 5.9e-65)"
                     /gene_kind="regulatory"
                     /note="ORF10"
                     /product="putative histidine kinase"
                     /protein_id="CAJ34390.1"
                     /transl_table=11
                     /translation="MALVSYELTRRTLLDERERTVLRAAYYDAAVVRAGLDTDNPDVAE
                     ALRALDTGTGRRPLVLLDGEWYARSADNGLTTIVPARLQDLVAAGEPAVQRVRVNDTPV
                     MLVGVPLSESTAFYEIASLRELEQTFQVLALALTAVAIMIAGSGAALGWYATRHGLRPL
                     TAVADAAERIAAGDFTTRLAPDTDPDLTRLSTSFNRMVDELAGRIDRDRRFAADVSHEL
                     RSPLQTLAAAASVLSRRRENQDERTATAARLVADEIDRFQQLVNDLLDLARGDQPVHRE
                     SVDLPELARQACRDRDLPESMVQLATGTPPGWRVDRRRVAQVLANLLDNAERYGAGPVA
                     VRLSHDADTGVIEVDDEGPGVPMEDREAIFDRFVRGRAANYRGGGDGTGLGLALVAQHA
                     AAHGGDASVSDRPEGGARFRVTLPGSLS"
     CDS             62300..62836
                     /codon_start=1
                     /db_xref="InterPro:IPR019606"
                     /db_xref="UniProtKB/TrEMBL:Q333T1"
                     /note="ORF11"
                     /product="hypothetical protein"
                     /protein_id="CAJ34391.1"
                     /transl_table=11
                     /translation="MFALLGACGVPAEDRPRAVTPPPVPFPATASAAPTAAETGAVTEV
                     LYFARDERLVPVIRRADQVPALDAQLRALLAGPTPTERDDGLTSALPGAFTSAVVELVD
                     GLARVTVGLTAVDTGRSDGRLAYGQIVCTLTARTDVTAVLFLEGGTPLSVPRADGSLSS
                     GPLTAADYAVLINPR"
     CDS             62925..>64650
                     /codon_start=1
                     /db_xref="GOA:Q333T0"
                     /db_xref="InterPro:IPR001404"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR019805"
                     /db_xref="InterPro:IPR020568"
                     /db_xref="InterPro:IPR020575"
                     /db_xref="InterPro:IPR020576"
                     /db_xref="UniProtKB/TrEMBL:Q333T0"
                     /note="ORF12"
                     /product="putative chaperone"
                     /protein_id="CAJ34392.1"
                     /transl_table=11
                     /translation="MNDRAETLEFQAEARQLLRLMVHSIYSNKDVFLRELISNASDALD
                     KLRLASMVDKDLAVDTGDLHIAIEVDRDARTLTVRDNGIGMSRDEVVSVIGTIAKSGTA
                     ELLRQLREAKDAGASQELIGQFGVGFYAAFMVAERVELVTRRAGETGGTRWESTGEGTY
                     TITELDDAPQGTAVTLHLKPADAEDNLHDYTAEWTIRGIVKRYSDFIAHPIRMTVERPG
                     TDDAPATTEAVTLNSMKALWARPRGEVEPAEYHEFYKHVSHDWADPLETIHMRGEGTFE
                     YEALLFIPTHAPLDLFSPQGRRGVQLYVKRVFIMDDCDALMPNYLRFVKGVVDAHDLSL
                     NISREILQQDRQIRAVRRRLVKKILATVKDLKTGQPERYRTFWTEFGTVVKEGLLEDTD
                     NRDTLLEILSVASTNDPAEQTDLAGYVERMREGQQDIYYATGENRSTIENSPHIEAFRA
                     KGYEVLLLTDPVDEVWVERVGSYAGKTLRSVAKGQVDLDTEQERTEAEAERERQRTEYA
                     DLLGWMGEVLADNVKEVRLSSRLTTSPACVVGDAHDLTPTLEKMYRAMGQEVPKVKRI"
ORIGIN
        1 gatccccagc cgcgaatggc agccacacag ctgcggcccc ggggccaaag gaccacgcga
       61 gtacctgtgg gcctggatca ccaccgccac cagcgcaggt gagcaccggt ggctgctgat
      121 gcgccgcaac cgcagcaccg gtgagctggc cttctacctg tgctggtcac cccgcccggc
      181 gccgctgcac accctcgtga ccgtcgctgg ttcccgctgg agcatcgagg agctgttcca
      241 gtccggcaaa ggccaggtcg gcctggacca ctaccaggtc cgcggctgga ccggctggca
      301 ccgccacgtc accctggcca tgctcgccct ggccgtcctg accatcctcg ccgctcggca
      361 gcccgacccc gacccggaga tcatcgcgct gaccgtcgcc gaaatccgcg ggctcctcaa
      421 cgccttcgtc ctcgccgtga cgctcccacc cgcgcacacc ctgcactggt cgacctggcg
      481 acgaacatcc caagcccgcg cccgacgagc ccactaccag cgcagacagg cgaagtgacg
      541 ttggagtact agccattgag ccgataattc agcgcacgac ttgccggaat cggtagggat
      601 ggtgtggcga ccatggccgc gatcgatgcc tgggcgcgtc ggcccggtcg acgccgagtc
      661 gggcgacgcg ctggcgggtg aaggtggccg cccgtcgaac tttacgactt gaataccagt
      721 atcggtgaag aggccgaaga ccgatatctg ccattacgta ccgatcatgt tgcaggaatg
      781 cccggaacct ttcggatgtc aggctgccag ttggcaagcg ggtgggtgcc ctctcccgca
      841 gggcttcgcg tagtcgcctg aacgtcttcc gacctcgcgt tcgtggtgtc gcggacctga
      901 ttggagggtg atttagcacg ggtgtggtcc atcggtgatc tgcagttgct gagacaacat
      961 gagacggaga aggaccacac cctcgcatgt catcgtcgct gatcgacgta acccgtcagc
     1021 atgccccgcc ccgcccgact caccgactgc tggccgcgag gcgcttggag gccctggcgc
     1081 gggttcccga tccgcgtgac ccgtgccaac cgccgcccac acgacctcat cgccaccgtg
     1141 aacagcagct accccactat gcaatgaccc tgctctgtcc cgtcgacggg acagagcgcc
     1201 cgccgccgga ggaagaaacc tgttgccgtc gcgggatgct gattatattc agcctcatga
     1261 ccctgctcat gaagcggcgg gcttcggtcg cgatgcgttt gttccgccga tatctcacta
     1321 aacgccggga ctggacagtg tgaacatcat tgcacttcta gctggttgac aacgtatcta
     1381 cggtcgccat ggttaattgt ggttgacggc gcgtgtcgcg actgcggagc gccatgtcgt
     1441 cgaatctcgg ccagccgtcg ccgtgacatt tgtcaaccag ctccgatgaa ttctgtgcac
     1501 tctgggggag ttgctgatgt cggtttcggg aagccgccgg agcgaaggct cctaccgtcg
     1561 ttcgggtggt tgtgcccagg gccgctcgcc ccggccagcc agggaagacg tcaagttcgt
     1621 ccgttggccg gccgagcggc acctacgcga cctgtgccgt caggagcgga tcccgtgcct
     1681 cctggtggtc gagggcggag cagagccgcc ggtctgcagt gatccgcgtg aggactgggt
     1741 tcgtacgccg atctcgccat ccgaccttga cgctcgggtg accgctctcc ggcaacgttc
     1801 tcacgaccgg cgtacgcctg ttctcgaccc ggccgggacg ttgtcgttca ggactgcgtc
     1861 cgtcgtcatg tccagtacgc acctcgaact catggatctg ttcgtcgaac gcttcggcca
     1921 ggtggtctac cgctgggagt tgatgaccat cctcacgaag cgcgactcga catcaacgcg
     1981 aaacgccctc gatctgcaca tcatgagaat gaggaagcgg atcgcgccgc tcgatctgga
     2041 tatagttact gcctggggcc gtggctacgc gctggaagaa aagtcctcat gggccgcggt
     2101 ggccagcaag cccgcggctg tcgatcattg ctgacatcgc cggccgatgg ctactcagtt
     2161 tcgtcgtggg tagtcttgtc gagggtctct gctgcggccc ggtcgagggt ggagacgatc
     2221 cactgatcga gttcgacgct tgattggtgc gcggcctggc gccatcgggt aaggcgtcgg
     2281 tcgggtatgg gaatgcgggg catcagtgcg gtcttgatgg tttctgttgt gcggtcggag
     2341 cgggtcgctt tgatggccgc gcggagttgt ttgaccgacc acatctgggt ttcggcttcg
     2401 tcgagccaac ggtcctgatc gtcgggagac attgcggcta cttcggcgtg gtgttggaaa
     2461 ctgaggccgc ttcgacggcg ggccagtggg aagcggccgg cgacccaggc gtagttgcgt
     2521 agggtctggt agtccagtcc tacagcctgg acgacgtgcc gatagcggtc ggcgtattgt
     2581 tccttgccgt acaccagcca gtcgcccagg caccaggacg aggagtcgac gataccggag
     2641 agttgggcgc cggttcgctc ccagtgttcg aagctcattc gttcgggcaa ccgtagaccg
     2701 accctggtca gcatcacctg ggccggctct gctgggcgtt gcttcggaac gccagccgtt
     2761 gctgcaggga ccacccggag cgctgctacg gcgttgcgtg acgatcggct acccgcgctc
     2821 atcccactca acctccccga cagtcggata actcgctatc tctgctctct ttttccgtct
     2881 cgcgccgtgc atgtgtgatc ggcgcgcgcg ggatgccacc cgtaaggccg cccttccgac
     2941 aaaggcggcc ttgcgggtgt ttccggttac ctcgaccgca ggctgtactt acgggtcgcc
     3001 agcggagcga agatggtgat cagcaggacc gaccaggcaa ccgtcagcag cacatccagc
     3061 cccggcggat tgccgttgaa caggtcgcgc agcgcgttga ccgtcgcggt catgggactg
     3121 gcatcggcgt acacccgcag ccaggtcggc atcgactcgg taggtacgaa cgccgacgag
     3181 atcagactga acgggaagat ccagatcagg ccggccgact gcgccgcctc cgggttgggc
     3241 accgagaggc cgatcatggc gccgacccag gtgagcgcgt agccgaacag caacagcagc
     3301 gcgagtccgc cgagggcaga caggaccccg ccctggaagc ggaagccgat cagcagaccc
     3361 atgagcacca cgaccagcat cgacacgacg ttgcgaagga tctccgacag cgtacgcccg
     3421 acgaggaccg cggaccggct catcggcatc gagcggaacc ggtccatcag gccgcggtcc
     3481 atgtcggtgg agatgccgat cgtggtgccg gcgaccgaac cgaacaacac catctgcacc
     3541 aggatgccgg gcagcaggaa ctgggggtag ttcccgccct cgacattgat cgccccgccg
     3601 aagacgtagg cgaacagcag gatgaacatg acgggctgaa ccagcgagaa catcaccagt
     3661 tcggggctgc gcgtcaggtg ccgcagattg cgcagcgcca tctgccaggc gtcggacagc
     3721 caccaggaca ggccggtctg ctgctgtgcg gcggcggcat cgagccgcgg tttcagggac
     3781 gtggagacca tcaccgctta ccacccttct tcttgctgtt cacgtcttcg gacgcccggg
     3841 ccgtggcggt gtgcccggtg agggcgagga acacgtcatc gagcgtgggc cggcggacgg
     3901 ccacgtcggc gattgcgatg ccggaatcgc gcagcggatt gagtagctcg ttgagcgtca
     3961 taccctcggg gaggggcgcg tgcacctgca tgccctccgg atcgccgacc ggctcggtcc
     4021 ccaacctctc gcgcaggatc tgggtggtct tctcgaccgc ggcggcgtcg atgagagtca
     4081 cgtcagccca cgcctggccg acctccgcct tgagttcgtc cggcgcgccg ctggcgatca
     4141 ccttgccgct gtcgatcacg gacagcgagt cggcgaggtg gtcggcctcc tcgaggtact
     4201 gggtcgtgag cagaaccgtg gtgccctcct cgaccaactc gttgacgatg cgccacacgt
     4261 ccatgcgact gcgcggatcg agggcggcgg taggttcgtc gaggaagatg agctggggcc
     4321 ggctcatcag ggtggcggcg atgtccagcc ggcggcgcat accgcccgag tacgtcttcg
     4381 cctgccggcc ggccgcctcg gtcaggtcga agcgctccag cagttcggtc gcccgcacct
     4441 tgatgtccgg cgtggacatc cggaacagct tgccgaccat gtgcaggttc tcccgcccgg
     4501 tcagcatgtc gtcgacggtg gtgtactgac cggtcaggcc gatgatggag cgcacctgta
     4561 gcgcgttgcg ccgcacgtcg aagccgaata tctcggcctt cccctcatcc ggcctgagaa
     4621 gggtggtcag aacccgaacg gtggtggtct tgcccgcacc gttaggtccg agcagaccgt
     4681 gcaccttacc ctccggcacg gtgagttcga ggtgatcgag agcggtcacc gagccgaatc
     4741 tcttgcacag tccagctact tcaatcgctg ctggcatctc caggattcct ctcaaagggg
     4801 ccaacgaagg tcggcgtgct gatcctggaa tctacccctg aacttccctt agaagctttg
     4861 accgcagaat gagcggcagc gagtcgctat agtctcaaac gtgatgtatt tccgtccggc
     4921 tgatctcgcc catgagcacg gcctttcccc gcaatcggta cgcaactacg agcgtgatgg
     4981 tctcatcccg cccgctcggc gtacggagag cggctaccgg cggtacaccg agaagcacgc
     5041 cgcagcgcta cgggcgtacc gcgccctcat cccggcgcac gggtacgccg aaagcggcgc
     5101 gatcatgcgg gacatcactg ccggacggtt gaacgaggca ttgacaacca tcgaccgcag
     5161 tcacgccgaa ctgctgcgag accgcggcac cctggacgct gtcgccgagg tcctgactca
     5221 cctgacggga cgctcgaccg gcacctggcg tgccccgaag agcattcagc cctacagcat
     5281 cggggagttg gcgcaccggc tcggcgtcaa tgtggcgacc atccggaaat gggagacgtc
     5341 gggcgtgctc gcgcccgtcc gccggccgga gaccgggcac cggatgtacg acgccagcga
     5401 cgtccgcgac gcggaactgg cgcacttcct gcggcgcggt cgctatccgc tcgagctgat
     5461 agccaccgtg gtgcagcagg tccgggcggc cggagacacc caggcgttgg ccgcggccct
     5521 cgcggactgg cggcagcgcg tcaccacgcg cggcctggcc atgctgaacg ccgccgcaca
     5581 actcgccagc tacctggcga tggaggagaa ctgatccggg gcccgacgcc cccgtgaccc
     5641 gctgcgccgg gactgttccg ggcgggtggg gccgtaccga ctccacccac cccgatctca
     5701 ctgcgtgtgg gcagtcggct gctcccacac caacgcgtcg tggacctgcg cccgaagctg
     5761 ccgcagctgg gcgaagggca gggtgatccg gcgggccaga tagtcgacgc cggtgctgcc
     5821 gccggtgccg ttgcgattgc ccaccatctt cgagaccagc gccaggtggg tcatcttcca
     5881 ccgccagtag ccgttggcca cgtcgagcag gctgtcggcg atgcggttga gcacgccggc
     5941 gccggggccc cgtgcgcaga cctcggcgac gctgatgccg ttgtgctcgg tcagccgctc
     6001 gaaggcccgg tagaggcggc cctcctgacg ctcgccgccg agcagccgcg cgagcaggcg
     6061 gaactgcgcc gactgcgcac cgctcgcccc gtcgaggaac gggcggaatt cggcgaagtg
     6121 acgcagcggc aaccgttcca gcgcgaccac ctgctcgtgc agtacccgga gcagctcagc
     6181 ggtgcgctgg agaaattcca gcgccagctc ctcgtcctcg ggtccgtagg gcggcgtcat
     6241 cgcgtccgcc gcggcgtcga ggtcgtacgt cacctgcttg agccacagct cgcaggcttg
     6301 atgggtgacg atgaagaagt gctcagccag taccacggac cggctcgcgg tgtccggggc
     6361 gcgggtctcc tgcagggaca gcagcgtgtc gacctgcagg tagtccgcgt aggtcagggt
     6421 cgtcatcggg cggtcccggg gcgttctcgt gcgaactcca gcagctcgcg tacgccgctg
     6481 cgcagcaccg acggcgctac gcacatggcg atccggatga ggtgacgcga ccagggcgcc
     6541 ggttcgacgg tgatgacccg gccccgggcg tccaggcggg gcatcagcgc gaacccggtg
     6601 ccgggaacca ccgcgacgtt ccgggtctcc agcagcccgg tggcgaactc ttcggcggtc
     6661 aggccggtcg gcgcgacgtc gagcactgcg taccagccac cggcgggcag ttcgggcagc
     6721 aggccggcgt cgcgtacggc gggcagcacc gcatcgcggt tgctgagcac catggcacgg
     6781 ttctcgcgta ccacgtgtcc cagccgcagc gcctccagcc ccgcgtattg caccggggtc
     6841 gacatcgcga tgaggttggc ctcctgcacg atccggaagg cgtgcgcggt ccggtcgttg
     6901 gcggtgctga cgtaccccaa tcggtagccg gtcatcgcca ggctcttcga gaaggagtag
     6961 gagctgtgca cgatccgctc ggagaccggc acatcccact ccagtgacgc ggtcgagacg
     7021 tgttcgtcgt cgaagacgaa gtgctcgtac gcctcgtcgc tgatgacctg ccagccccgg
     7081 gcgcgcgcca tgtcgatcag cgtgctcagg gtcgccgtgt cgaggacggc cccggtcggg
     7141 ttggcgggtg agttgatcaa cagcactctg gtgttcgcgg tcgaggccgc cagcaccgac
     7201 tcggggtccg tccggtagtc gcgtcccagc gggtagaaca ccggacggag accggcgagc
     7261 agcacctgct gcaggtggat gggccagtgc agctccggca gcaggatctc cgcgtcgggt
     7321 tcggccacgg cctgcatcag cgcggccagg ccctgacagg agccgggggt gacgaagagc
     7381 cgggacacat cggtgtccac gccgttctgg tcagcgagct tctccaccag acgctcgcgg
     7441 agctccagca gcccctcgac cgccgtgtag tcggtgcgcc ctgcggtcac cgcctccgcc
     7501 agcgcctgcg cgacctcggg tggcggggtg aagtagggct cgccgacatg cagcttggtc
     7561 accggaacac cgctgatgcg ctcgcgctcg ccggcatcgc ggaagacgcg atgcagctcc
     7621 gacgacggaa tcgtcgacgc gaccgaggga ccgtcgagca ggttgggata ggggcttggc
     7681 aggggcatct aatctccgtt tcgatcgtga cggcggtacg gggagggcat caggaggtgc
     7741 gaccgccgtc gacgggaatc agcgctccgg tgatccagcc ggaaaactcc gggtcgagca
     7801 ggccgcacac ccacccggcg atctcggcgg gctggccgaa ccggcccaaa ggggtcgccg
     7861 cgagcagcga cgaccgcagc aacgcggact tcacggagtc caggcccatg tcgtcccaca
     7921 tcggtgtgtc cacgggtccg ggtaggacgg cgttgaccct gacgtccggg gccagttccc
     7981 gggccagcga tcgggtcaga ctgttcagcg cggccttgct ggcgccgtag aaggaccgcc
     8041 ccggcatggc cagcacggca ccgacggacg acacgttcac caccgcgccc cgatgctcac
     8101 gcaggtgggg tagggccgcg cggatcaggg cggccggtgc gcggacgttg gtggcgagca
     8161 gccggtcgaa gtcctcgtcc gacgccgtgt cgagcgtcgc gaagcgggcc agcccggcgt
     8221 tgttgaccag accgtgcacc gtaccgaagc gggtggtcgc ggcggcgacg acgtgttccg
     8281 ccgcgcccgg ctcggtgatg tcggcggcga cggtcgcgac ctgcccgcca ccgtctccgg
     8341 tcagctcccg caacgccgcc tcgcgacgcc cgaccgcgac cacgttcgcg tcgcgggcca
     8401 gcagtcgttc gccgatcgcc cgtcccagtc ccgtgccggc cccggtgacg atcaccgtac
     8461 gaccggcgag gccgtcgccc cgctcagcca cggcgggcca tgcctcggct tcggttgggg
     8521 acaccgacgg cgtggctggc tgggacggcc ggccgccgag gtgtgcacgg ccgatatccg
     8581 cgtccggtaa cgcgatgagc ggttgtgacc atggcctccg cctcgaccag actggtgttc
     8641 gagctccaat ctcccgcctg ggaggcggat cggcatccat tccgacagaa ctgagccaga
     8701 tgcgcccgcg gccctaccga ggcttgtgac gatgcgggca gttacgactt cgccgccgga
     8761 tctccggatc ccgtacggaa ggttctgtcg atgagttcgc ccacggccag caccagcgcg
     8821 ctcgacctca ccgacccgac gacgttcgtg cgccacgaca cgcacgtgtt ctgggccgag
     8881 gtgcgtgacc acaatcccgt ctactggtac cagggccgcg aggaccgccc cggcttctgg
     8941 gtggtatcgc gatatgtcga cgtggtcgcg tcctacaccg acgctgcgag gttgagctcg
     9001 gcgcgcggca ccgtgctgga cgtgctgctc cggggcgagg actccgccgg cgggcggatg
     9061 ctcgcggtca ccgatcggcc gcgccaccgt gaactgcgca acgtcatgct ccgcgcgttc
     9121 tccccccggg tgctcggccg ggtcgtcgag caggtccatc gacgcgccga cgagctgatc
     9181 cggcgggtca ccggtaccgg cgccttcgac ttcgccaccg aggtggccga gagcattccg
     9241 atgggcacga tctgcgacct gctgtcgatc ccaccggcgg accggccgga cctgttgcgg
     9301 tggaacaaga acgccctctc ctccgacgag gccgacgcca acctgtatgc cgcgctggag
     9361 gcccgcaacc agatcctgct ctatttcatg gatctggccg agcagcggcg ggccagtccg
     9421 ggcgacgacg tgatcagcat gatcgccact gccaccgtcg gcggcgagcc gctctccatc
     9481 gacgacgtcg cgctcaactg ctacagcttg atcctcggcg gtgacgagtc ctcacggatg
     9541 tcggcgatct gcgcggtcaa ggcgttcgcg gacttccccg accagtggcg ggccgtacgc
     9601 gacggtgacg ttgcgatcga caccgcggtc gaggaggtgt tgcggtggtc cacgccggcc
     9661 atgcacttcg cccgtaccgc caccacggac ttcgagctgc ggggccagca ggtgcgggcc
     9721 ggagacatcg tcaccctgtg gaacctctcg gccaacttcg acgagcggga gttcgaccgg
     9781 ccctaccggt tcgaggtggg gcgtaccccg aacaagcacc tgtcgttcgg ccatggcccg
     9841 catttctgcc tcggcgccta ccttggccgc gccgagctgc aggcgttgct caccgcgctg
     9901 gtcggaaccg tttcgcgcat cgagtccgcc gggtcgcccc ggcgcgtcta ctcgaacttc
     9961 ctcaacggcc acagctcgct gcccgtcgcc ttcacgggtc gctgacccgg ccaggccctc
    10021 accccgatgt gcgcagggtg accttgtcga ccttgccgac ggcggtgcgg gggaactcct
    10081 cgatcggcac cacccgatcc ggaatcttgt aggtggccag accgcgctcg cggaggaagg
    10141 acttgacagc cgccggactg atcggctcgt cccggaggat gacgaaggcg acggtcttct
    10201 cgcccagcac cgggtcggcc acgccgacca ccgccgcgtc gcggatcgcg gcgtgggcga
    10261 gaaggtgctc ctcgatctcc tcggcgggta ccttctcccc gccgcggttg atgatgtcct
    10321 tgatccgccc gaccaccacg atgctgccgt ccggccgccg gcggaccatg tcgccggtgc
    10381 ggaagtagcc gtcgggggtg aacgagcgcc ggttctgttc ctcggcccgg tagtagccgc
    10441 ggatcgtgta gggaccccgc accagcagct cgccctcggc gccatcgggt acgggtcgac
    10501 cgtcggtgtc gacaacgagg atctcgtcgt gcgcggccag cggacgtccc tcggtggcga
    10561 gaacgacctc ctccggatcg tccaggcgcg tgtaggtcag cagcccttcc ccgacgccga
    10621 accactgtgt cagcacggca ccgaggctgg tccggacctc ggcggcgcgg gcggggtcga
    10681 acttggagct gcccacctgg agcatgaggt tggggaaccg gacgtccgac ttgcgggcgg
    10741 cgtcgagcca cagccgcacc acgggcggca cgagcgtcgt gagcgtcacc cgctcccgct
    10801 ccaacagctc gaacacctcg tccggccgga cgctggaggt gagcactgcg gtgccgccga
    10861 ccagcagtgc gccgaggacg ccgggacagc cgagcgcgga attgtggccg atcgggttga
    10921 ccgccaggta cacgtcctcc gcgccgaacc gcagcgcatc agccgtggcg cgcatgttgt
    10981 aggcgtagtc gtcgtgcgtg cgtgggatga gcttgggcag gccggtcgtg ccgccggaga
    11041 gcaggaacag cgcgggctcg ctggggtcga cggcaggcag gtcacgcccc cgccggtaga
    11101 ggtccgccag cgcggtgaac tcctcggcgt caccggcgac cacgacatgc ttcagtgcgg
    11161 gcacctcggc ccgtacctcg cgggccagcg cgcggtggtc gaagcccttg acctggtcga
    11221 cgacgaccag ggcgaccgcc tgcgaatgtg cgcacaggtg ggtcagctcg accttacggt
    11281 gtcccggcag ggccatgacg gggatggcgc cgatccgcag cagcgcgtag accaccacca
    11341 cgaactcggg cacgttgggc agctggacga cgactcggtc caacggttcg atgcccacgt
    11401 ccaacagccc gcccgcgacg tctgcggatg ccctcgacag ctcggcgtag gtcatccgcc
    11461 gctcgccgca gacgagtgcg gtcttgtcgg cgtgccgggc acatgcctcg gtcagcaggt
    11521 ctcccagcgg ccgtccctgc cagtacccct cgcggcggta gagcgcggca agttcctcgg
    11581 gccagggcac acaaccatcg agcatcgctt ccacccaaca gagtcgaggt agttgaacag
    11641 acacggcgtc tcgacgccat tgccacagcg tgacccaagc cgtgcggccc ggacggcacg
    11701 gcgacaggga cgcgaaagga gcgtccgtgg cggcacttgc cctgtcgcaa tcctttcgtg
    11761 gccgggcacc ggcgcgcgag cgagcagcta ggttcgggcc ccgtgcagcg ccctcgtacc
    11821 cagtaccgag aggacggagt gagcaggtgc ccaccgttgc ggaattgttt gagtccgttg
    11881 ttgcgcgctc gggcgaccac gtggcggtga tcttcggcga ccgcctcgtc agctatgccg
    11941 aactcgacgc ccgcgcaaac cggttggcgc gggtgctggt cgagcgcggc gtcggccccg
    12001 acaccaccgt ggcggtggcc atgccgaagt gcgacgagct gatggtggtg ctgctggcgg
    12061 tgctcaaggc cggcggcgcc tacctgccgc tggacccgca gtatcccgcc aagcgactgg
    12121 cgtacatggt gcaggacgcc cggcccacgc tgctggtccg gatggcgcag gtgtcgctgg
    12181 aactcggggt gccggtcgct gaacttgtcg tggacgaccc cgacacggcg cgggagaccg
    12241 agtcgcggcc agatcaccag ctgaccgacg ccagccgcaa cgctccgctg cgcccggaca
    12301 acctgatgta cgtcatctac acctcgggct cgacgggtac gcccaagggc gtcgccgtga
    12361 cccacaccgg cgtcgccgac atcgtggccg cccagaccgc ttccatcgcg ccccggccgg
    12421 gcgaccgcgt gctccagtgg gcgtcggtca gcttcgacgc ggcgttctgg gactggtcgg
    12481 cggcgttgct gtccggtgcc acgctgatca tggccccggc cgacgaactg ctcccgggcc
    12541 aaccgctgcg cgacaccctg cgccggtacg cggtcaccca cgccgtgctg cccccggtcg
    12601 cgctgagcgt caccgagccc gacgatgtgc tcgtcggcgg cacgctgatg tcgaccggcg
    12661 atgcgtgcac ccgcgcgctg gtggccaagt gggcgccggg ccggcggatg tacaacggct
    12721 acgggccgac cgagaccacg gtcgggtcga ccatcgccgg gcccatcgcc atctccgacg
    12781 agatcaccat cggtacgccg tggtcgggca acagggtgta cgtcctcgac gagcgcctgc
    12841 gcccggttcc gaacggccgc gacggcgagc tgtacctggc cggcaacggc ctagcccgcg
    12901 gctacctgaa ccggccgggc ctgacggcga gccggttcgt gctcgacccc ttcggcccac
    12961 ccggcggccg gatgtaccgc tccggcgacc ggggccaccg ccgcgcggac gggcagttgg
    13021 tcttcgccag ccgcggcgac gaccaggtga agatccgtgg cttccgcgtc gagctcggcg
    13081 aggtcgaggc gcggctggcg gcccaccctg cggtggatgt cgccgccgtg gtcgtggtcg
    13141 gcgacctcgc gggcgcccgc ctggccgcct tcgtcagcac cgtggccggc accggggttt
    13201 cggctgccga actgagcgca cactcggcgg agaccctgcc ggaacacatg gtgccgtcat
    13261 cggtgcaggt gttacagcgg ctcccggtca ccgccaacgg caagatcgac cgggcggcgt
    13321 tgcgggacct cgccgagtcg gcggcgcacc ccgacgcagc agcctcggcc ggtcctcccg
    13381 gcgaggatcc gacctcggtg gagagccggc tatgtctgct ggtcagggag cttctggcgg
    13441 tgccggacgt caggccgggc gacaacttct tcaaactggg cggccactcg gtgctggcga
    13501 cccggctcgc cggacggctc cgcgacgagt ggggaatcac cgtgccgatc cgggcggtgt
    13561 tcgaggcggc caccctgtcc gagctcgccc tggtcgtgca ggcgtcgaag gcatccatcc
    13621 ccaacgggcg cccctgacgc cgacgaggaa ccgaaccagc gttccggcca cacaggaaag
    13681 accccctcgg gcgatgccgg accggcaccg cccgaagggg gatccatcgg ctacctgggg
    13741 ctacagtgcc tggggcagtc gccacgccgg ggcgggcccc accaaccggc ggtgttgtgg
    13801 ttgtttccgt tgcgcgtcgc gaccgcgaag ccggcggacc ggcccgaggc gttgaccgcg
    13861 atgacgtacg agcccaggtc gttgtcgccg aggcgggtcg tgcgtccccg gcgcggctcc
    13921 cacatgaccg cgctgaacgg gtacgccgac gagccggtga agttgcggat gccgacgatc
    13981 tggccggcgt cgttgacccg gtacgccacc cgaccgggaa gctccaccgg ctgggcgttc
    14041 gcgctgggcc agtagatggc cgtggtggac tggccggttg cgttgatccg ccaaccgacg
    14101 atcaacccgt tctcgttgcg gtcggtggcg tacgtgtcgg cggagccgcc ggtgggaagt
    14161 tgctgcacgg cgagggtgcc gggctgccat accaccgccg tgtggtgcca ggactgctcg
    14221 ccgacctggg tgaccagccc accggccact ccgccgcgct cgtccagcgt gtgcgcgagg
    14281 gccaccggtc cggtgaccga cgtggtgggt ggcggcagcg tggtgtacgt gcggctggcc
    14341 gggttccaca ggtacgagcc cacgggaaga ccgacccccg tggcgttggt gccgaccacg
    14401 aggaccgtgc ccttgtcgtt gatgtcgacg gcctgggcac cgcccgcgcc gggcggcagc
    14461 ggcaggacgt cgagcccggt gcgcgcttcc cagacgaaag gctgaagcag cggctggctg
    14521 ccgtccggcg cgggcgtcgg cggcccgatg cccagcccga gcgtgccagc gacgacgccg
    14581 aagcggttga tcgcctgcgc tcgcgagcta cccgcctgcg acggcgtgat ttcgatcagg
    14641 cggccgccct tgtgccgcgg gttcgcgatg aaggcgtggg ccgtctgggt gcccgggagc
    14701 gacgtcacgc cgaccacgtc gccgcggtcg ttgaggtcgg tggcctcact cggcgtaccg
    14761 ggtccggcga gcgacccgag gtcgtggaac cggctgagcg cctcggcggg tgcgccaccc
    14821 ggcccggacg acgtgctgcc ggtgcccctg agatgggggt tcgcgatgag cgcgtgggtg
    14881 gtctgtgtgt cggcgagcgt ggcgacgccc agcacgtcgc cggacgcggc gaccggttcc
    14941 acctgatgcg aggtcgccgt cagtgccagt atcgcgacga ccgtcagggt gcggactccc
    15001 gtcaccaggt cacccgcacc ggtccgacgc caccgcgcgc caacaggttc aggtcgtagc
    15061 gggcgacctg gcggccgagc gcggcgccga cctcgtcgga gtagcggaag tggacacccg
    15121 ccaggacccg ggcgtcgatg ttctccttcg tcaacgtcga ccacggcgtg ccacgccggt
    15181 agttgcgggt caccacccgg ccgtcacccc gggcgaaggt gatcgagaac gccatcgggg
    15241 tgcagggtcc gaccagctgc gaaagcacct gttcggcggc cccagcggtg accgcgtggc
    15301 cgctggggta ctcgggatgc ggcggcgtcg gcaggaacga gttccaggtg gggtcggggg
    15361 cggtacgggg atcgccgtcg gtgtcggcgt cgcggatggc cgtgaccggc cgccagtgca
    15421 ggagggcgta cttggcctcg aaggtggcga tgctggaatc gacgatagcc gcgccgagcg
    15481 ccgccagtag ccgcaccttg ctcctgcggg accgggccga atcgccgacc agcaggcgaa
    15541 gcaccggcac gtactgcgac agggggtcca gccacgccag gtcgctctgc gcctcggtgc
    15601 gctcggaaac ctctccgccg agacggcgta cctcgtccag ggcccgccgg taaggggccg
    15661 tgcccagggc cggcggtggt ggcgggcgga accgatcggc ccggccgagc aggaacgggc
    15721 gggccagccc gtaaccggcc gccaccgtct gggtcgcccc gggcgtgagc cggtagaccc
    15781 ccggtgcctc gggcggcagc gtgaagggca cgttcaccga cgccaggtcg aggccgtcac
    15841 cggtacgcac cgcgaccatc gccgccgcgg cctcccgacc ggcggcgatg cccgccttct
    15901 tggcctcgct cgcggccagc ccggccagcg agtcggccag caccccgtcg agcttgtccg
    15961 cctggccggg gaccagtgcc ttcagcacac cgtgcaccgc cgttgcggtg gcggcatcct
    16021 cgaacaccgc ccgctgcccg ggtgcgcgca ccggtgccgc ccgccgtgcg ctgagcgccg
    16081 cccacgcggc aatccagctc atcgcccaca tccgctcggg cagcccggcc gtcggtgccg
    16141 ccgcgaacgt cgccagcatc tcgtcgaacc aggggcccac gacgtccggg cgggaaccgt
    16201 gccggggcga cgccgtggcg gcctcggcct tggtgggcag gatcaacagg cccgcggtgc
    16261 cggctgcggt gctggccgcg gcgatcagca ggccgcgtcg ggagagcccc ggaaccaggg
    16321 gggataggga cggttcggta gatcttgtcg tcatcgccat gcctttccat cggatacggg
    16381 acgggggttc ggtgaggggt ccggttcggg accggtcggg ttcagccaca ggctggttca
    16441 gagccggctg agcagcgccg cccggtcgac cttccccgtg ttggtcaggg gcagttcgtc
    16501 gagggcgacg atgcgcgtgg ggaccatgta cgacggcagg atcctctgga gggcaccgac
    16561 gacctcggcc gtgggaagcg gctcggccgt cggaacgtag aaggcggcca gcgtccgtcc
    16621 gcccggcccc gagggagcca ccaccgaggc ggcccggacg cccgcgcact gtaggagggc
    16681 gctctgcacc tcgcccagct cgattcggta gccgcgtacc ttcacctggt cgtcgaggcg
    16741 ccccaggaac tccaggtcac cgcttggcag ccaacgggcg cggtcaccgg tgtggtacat
    16801 gcgttcgccg gtgcggtggg cccacgggtc ggggaggaat ttggcggcgg tcaggccggg
    16861 ggaccgggca tagcccaggg cgacgcattc accggcgatg tacagatcgc cctccgcgcc
    16921 gttggggcag ggccccaggc cgtggtcgag tacgtagtag cgggcgttct gcatcggctt
    16981 cccgtatgga atgctcggcc acccggggtc gacgtcgcct acccggtagt ggttcgacca
    17041 gacggtgcac tccgtcgcgc cgcccagggc caccacctcg gcgttcggga aagcggcccg
    17101 gatctggtcg ggcagcggca ccggaatcca gtcgccgctg aggaggacca ggcggagcgt
    17161 gccacgcccg gccggctcgc ggacctggac gaagggcatg accatggcca gggcggcggg
    17221 tgccgagtcc cagatggtga tctcctcctg ttcgaggagg tccaccaggg tgtccggttc
    17281 ggccagttcc gccgctgacg ccagccgtac ggacccaccg gcggccagca cgccgaagat
    17341 gtcgtagacc gagagatcga agcagaacga ggtgacaaag aggatctggt cggtcggccc
    17401 gacccggtag ctgcggttca cccagtcgat gaggttcact gccgaccggt ggctgacgac
    17461 gactcccttg ggtgcgcccg tcgagccgga agtgaagatg gtgtagcaga cgtcgtcggc
    17521 cgtcgggccg gtggcgagcg gctcgctcgg gcgcagctcg atgtgatggc cggtccacag
    17581 cggctcgcgt cccgacgccg ggcggtcgcc ggatggcgcc acgcggatca cggcgtcgta
    17641 ccgctgggcc agctcgccgg tgaacgtctc gacctggcgg cggtggacgc tgccgccggt
    17701 caccccgggc aggaactcgg gaagacgttc gatgaagtgc ggtgcgaccc ggatgccgga
    17761 atagtcactg agatccgggt cgatcaggtc ggcgagcacg atgacgccgt cgtcggcgag
    17821 cagtccgagc agcgacccga ggacgctgag caaatagtcg aggtccggca ggaactgcac
    17881 ggtgctggcc agcaggatga cgtcgaacgg accctggacc cgctcggcta cctcgtgggc
    17941 gaagcacact acgccgtcga cctcgccgcc ggcgcggaac ccgccctcct ggctgcgcgt
    18001 cacggacacc ggtgaggggt cggcggcgac gtagcgcgac gcgcgcgggg ccagggcttc
    18061 gacgatcaga ccggacccgg atccgatctc gaggatcgag ggtcgtgccg cggccgtcgc
    18121 ggccagggcg aaggcagcca catggtcgcg gtactgctgc acatcgttct cgtcgaaggg
    18181 acgctccgaa cggcgcatgt tgaagccggc ggcctcgagc tggtcggggg cgctcgacac
    18241 gaagtcgaag aagttcacca cgaggtcggg ccggaaggtg gccgaccacg agaactcctc
    18301 ggcgatgtcg gggcagagca cgtggcgcag cgagcgcacc tgccaccgaa gctcctgcat
    18361 ggagcgcagg tgggtgcggt cggtcagcac cgcggccacg tcgagctggt cgagcagccc
    18421 gaccacccgg cgggcgggcc acgacggatc gatcggtacg taggcggcac cgcacttgag
    18481 cacggccagc agcccgacga gggccggtgc gtcacgctcg ccgaagagcg ccacggtgtc
    18541 gccccgtccc acgccgagat cgcgtagcag ccgcgccagg cggttggcgc gccggtgcag
    18601 ctcccggtgg gtcaggacct gcttgtcgga ggtcacgatc gccgggcggt ccgggtgccg
    18661 ttcggcggcc tcagcgagca gatcggggat cgtgacgtcg gcgcggaagt gtcgtgcggt
    18721 ctggttccat acgctccagg gcacgcccgg agacagggct ggcggggcgc tcatcgggcc
    18781 agcgacccga acgcctcgtg ggccgccagc gcgtcggtca gctcgttgac tgtcggatgg
    18841 tcgaagaaga gcttgagcga caagcgggtc ccggccagcg caccgagccc ggccatgatc
    18901 tcggcgatca gcagggagtg cccgccgatg gcgaagaagt cgtcgtcgtt gtcgaaccgt
    18961 tcgtgttgga gtgcggctgc ccacccggcc cgtacgtggg cacgcagcaa ccctcgcgcc
    19021 gagccgtcgt tgccgtcgcg atccgggttc gccacctcgg ccgatccgat gtcgttcacc
    19081 actcgcttcc ggtcctctcc cggtgccctg cctctgcaac tgcgggccgg tgccgcccgg
    19141 tccccgaccg tgcccggccg gtgccagtct caccgcggtg gtccgccgtt gtctgcggat
    19201 ctttcagagg tcagtcaggg ttggcgctga tgggcgtcgg cgcggcaatc ctcacgtgca
    19261 tgggaacgag aacgaagaat cggtggttcg tagaggtctc gcgcagtcgg ctcaaggagt
    19321 gtgccttgta cgccattccg cacgccggcg gcggggtggc cacagtgcgc agtctctgtg
    19381 tcgaactcgg cgacgcgttc gacaccttcg gcgtgcgcct gccgggacgg gagtcccggc
    19441 tcggtgaccc ggtggtgacg gtcatgtccc ggctcgccga cgaactcgcc ggcgaactgc
    19501 tccgccatgc ccaggggcgg ccggtggtgc tgtacggcca ctgctccggc tcggcgatcg
    19561 cctacgaggt agcgcgccgt atggaccccg cccagctgcg gggactcgcc gtctcctcgc
    19621 atccggcgcc cggcagcgtt cggcgtgcgc ccacctggga actgccgcga caggagttcc
    19681 tcaagcaggt cgtgaccgac gggtacctgc cgcccgagat catcgccaac gaggaactgc
    19741 tcgacatcta cgagcccgcc gtacgcgccg attacgagct cgtcgagacc tacgagttgg
    19801 acctgttcgg gggtgggccc gtcgaggctg tcgccgcgcc gacggtggcc atccacggtc
    19861 gcgacgacca caccatcgac ccggtccaca tcgatgcctg gtcggccctc accaccgggc
    19921 cgtttcgggt cgtgtcgctg gcggggggcc acaacctgct cctcggccga ccggcggagc
    19981 tggccgcggc catctgccag ggcctggcct cagacaaccg actccatgat caccggtagc
    20041 ggccggccca ccgcccgtca cgtggcacag gtgcctgccc tgctcggccg actggtcgag
    20101 cagggcagcc caccggtgat cgagggccat cagggaagtt gctcacgccc actcccggcc
    20161 catgatgtcc gagaccagcc cgtcgacatc gatggacaca tggaagtggc cgcccggtcg
    20221 caccgtcagc cggaactcgc ctgtggtgac gtccgcccac tccgtcagcc tcgactcgtc
    20281 caccagcggg tcgccgacgc cgtgataaca actcaccggg cacgacagcg gcgtggttcc
    20341 ggagccgggc cggtagttgg cgtgcgcgcg caggtccgag cgcagcgtcg gcatgaacaa
    20401 ctcgcgtagc tccgcgatct cggcgacccg ggggtcgatg ccgcccagag cgcagatggc
    20461 cgcccagaac tcgtcatcgg gcttcaggtg aacgtcccga ttcttcatct ggccgggtgg
    20521 gaggcaggcc gaggcgcaga gcctcctcgg ttccaccctc atgtcccgca gcaacatcgc
    20581 ggtctcgtac gccaccatgg cgcccaggct gtgtccgaac agcacctggt cgcggcaggg
    20641 cagctcaagc aactccacca cgatgtgccc ggccatctcg gccacgtcgt ccacgaggtg
    20701 ctcggcgaat cggtcaccgc gtccggggta ctggacggcc acgagttcga cccctggtgg
    20761 catcgcgttc gcccagtcgc tgaaggcggt cgccgagcct cctgagtgcg gaaaacacac
    20821 caagcgcccg gtgggcttct cgaccgtggt cagcgtgcgt atccagccct tcttccgcat
    20881 ccagctcatc gatccgtcct tccgattggt ttccgctttg cactggatgg tcgtcgttct
    20941 gacgtcactc aggtcattcg tgaaagaaat tggtcagaca tagctggtgc aacggttgct
    21001 ggccccaggg ttggttctgg ccgacatctt tcaggccgtt tgaggactca acaacccgtt
    21061 catagtgtgg ggctcacgaa cgacggcggc ttccgccggc cgtggctggg gagctgcgta
    21121 cgggaggacc caactgcgct ccgccgcgag tcagtgacga tcgagagtta cttattcggg
    21181 agtctggatg ggttacggcg gtgtttcgtc ggcgcaggag gcaatgtggc tggaacagaa
    21241 tcttgcacct gaggtgccga acagcaccac gaccatttgg gatgtgcggg gcgagctgca
    21301 cctgcctgat ctcgaggacg cgttgcggac cgccctgggc gagacgagcg cactcctggt
    21361 gaacttccgg cgggagagcg atgagctgcg gatcgtcccc cggaagctgg acgcgtggga
    21421 gcccttccgc attgacgcga gcgacgccgc cgaccctgcg gccgcggccc gggaatttct
    21481 caccgaacag attcgccgcc cgttcgacct cggtgcggat gcgctgttcc ggatcggaac
    21541 ggtccggctg ggcgacgggc atcatctgct gtgcctgatc atgcatcaca tcctgaccga
    21601 cgcgttcggc gtgttcaccc tgctctccca gcgcgtcgcg gagatctacc gcgccctgcg
    21661 cgccgattcc cctgtgccgg accggccgga cacgcctgcc gagatcgccg gcgaacggga
    21721 ggcgacgtac cggtcgtccg aaaggttcac ggacgcggcg cggttctggc gtgattacgt
    21781 cacggccggc ggcacggctg cccgactgcc gaccgggatg cgggcgggcg cgacccgtac
    21841 ggcgagcgtc gggttctggg acggtctgac cgcaccgctg ggcgtcgcca gctacaccgc
    21901 cagcgtggcg gcgagcgagg tcgcccggtg gcgggcggct gccgattcga ccgaaacgag
    21961 cgtcccggac ctgctcacct cggcggccac cgccttcctc caccgcctct gcaacacgcc
    22021 cagaccgatg ctctccttca ccgtcaacta ccgcaggggg gacatcaaac aggcctgcgg
    22081 cctgtactcg aacgccctgc cgctggtgat cgaggtgccg gcggcaggcg acttcgtcga
    22141 cctggcgaag tcggtgcgtc tcgagcgtct gcgggtgctg cggtacgccg agtacaacgt
    22201 ctccctgatc aagcgcgcgg ccggtcacgc gggcgacgta cgcagcccgt tcggccccgt
    22261 cgtcaacgtc attcccttcc tccgggaact cgacctcgcc ggcgccgtcg gacggttcgc
    22321 gggcggcacg ttcgggctac ccgacgaggt ccgtatctcc acctacgtgg acggcggccc
    22381 ggacagcgac ctgtacatcc gcttcgacgc gcccggacgg ctgtacaccc acgaggacat
    22441 cgccgggctg gccgagaggt tcgtgacctt cgtccgggcg gccctgaccg acccacgggc
    22501 gcgggtccgt gacatcagcg ccatcgggga gcaggaaaga gtcgcgctcc tcgaccgctg
    22561 tgccggcccg gtagtcgagc tggccggcgt gacggtgccc gtgctgctcg acatgcaggc
    22621 gctggccaca ccggatgcgg ccgccgtcgt gcacgagaac gccgtactga cctaccggga
    22681 gctggccgcg aggtccgacg ccctggcccg cagactcgcc gagtgcggcg cgggaccgga
    22741 acgtctcgtg gcggtcgccg tgccccggtc gatcggcctg gcggtcgcgt tgtgcgcggt
    22801 cctcaaggcc ggcgccgcct acctgcccat cgatccggac tctccggcgg agcgcgtgga
    22861 gttcatgctc ggcgacgctc ggccgacgct gctgctcacg gtcgccggga ccgacggact
    22921 ggccatcacg cccctgcacg gagcgcagcc acgctgggag gccagcgtta tcgagcggac
    22981 gaccgcagcg tcaccggcgg ccacgtcgca ggctggcggc accggcgagc acgccgcgta
    23041 cctgcggtac cggtcggggc cattcggtcc ggcggccggc gtcgtggtga cgcacgccgc
    23101 cctcgtcaac gagctgctct ggatgcagca gcgataccgg ttgaacgaca ccgaccgggt
    23161 gctgcacaag gccccggcat ccctcaatgc ctccgggtgg gagatcttct ggccgctgat
    23221 cgccggtgcc accgtcgtca tggcgaccca ggacgtccac ggggacgcga ccgcgctcgc
    23281 ggcgatgatc cggcggacgg gtgtcaccac cgtgcacgtc gtcccgtccg tgctcgccga
    23341 gctggtgcgc gacgaagccg ttgtcaccgc cggcaagggt ctgcggcacg tcatgtgcag
    23401 cggggaagtg ctcccggccg acctggcagc ccggttccac gagagctgcg acgtcccggt
    23461 gcacagtctt tacgggcccg tcgaggcgat gccggtcgtc acgtcgtgcg actaccgacc
    23521 cggctcgccc acggtaccgc tcggacgacc gatctcgaac gccggcgtct acgtgctgga
    23581 cagccaactc cagctgacgc cgccgggagt ggtcggcgag gtgtacgtca ccggcgtggg
    23641 tctggcccgc ggctacctgc accgcccggc cgcgaccgcg gaccacttcg tcgcgtgccc
    23701 gttcggcccc gccggcaccc gcatgtaccg caccggtgac ctggcgcgct ggaccgacga
    23761 cggggaactc gagcacgccg gcagcgccga ccagcgggtg cggatacgcg gcttctgggc
    23821 cgcgttcctc gagatcgaag cagttctgac cgcccacccg ggagtggacc aggccgccgt
    23881 gatcgcccgg cccgacggcc ccgaccgcgc cgcccagctg atcgcctacg tggtacccgc
    23941 gaccggcggg cggatgggtg cggccggcct ggacgtggac ttcagcgccg ggctggacgt
    24001 ggtcgagctg cggcggttcg tcgctgcccg gctgcccgaa cacctcgtac ccgccaccat
    24061 cgtcgtactg gaccggctgc cgctcacggc cgaagggaag cgggaccacg ccgcgctgcc
    24121 cgaaccccag gccacccgac gggcccaccg ggtggcccgg accgccgagg aacgcctcct
    24181 cgcggacgcc ttcgccgagg tgctgggcgc cggccgcatc ggtctggacg acgacttctt
    24241 cgccctgggc ggcgacagca tctcggcgat gcgggtggtg gccctcgccc gtgccggcgg
    24301 cctcgcgctc accgcgcgta ccgtcttcga atgccgcacc gtcgccgccc tggcggccgt
    24361 ggcggcgccg gccgacgaac cagcggtcgc cgctgcggcc gagggcgacg gcggacgcga
    24421 cgacgccggc ccgatcccac ttccgccgat ggcgcggctc ttcgccgaac gtggaccggg
    24481 cctggaccgg ctggcccagt ggctggtgct gacgctgccg gcggagatga gccccgacct
    24541 gctcaccgga gcggtccgag cggtcctgga ccggcacgat gtgctgcgct cccggctggc
    24601 cgacggtcag ctgctgatcc agccgccggg atcggtggac gtcgacaagc tcatccggca
    24661 ggtgccctgt tccggtgact ggagcgggcc ctcgtggccg gcgttactgg cggacgaggc
    24721 cgcgaaggcg gtcggtcagc tcagcgcctc ggccgggcag gtgatccgca tggtctggtt
    24781 cgcgccgccg ggcggtgcac ccggaagact gctcatcgcc gcccaccacc tggtcgtgga
    24841 cggaatgtcg tggcgggtgc tcgtcccgga cctcgccgag gccgcggcac agatccgatc
    24901 cgggcgtacg ccggcactgg ccccggtggg cacctcgctc cggtcctggc tggacgaact
    24961 cgcggccgaa gcggtacggc ccgagcgcgt ggccgagctg gaactctggc gcggcatcct
    25021 cgcaccctcc ggcgatccgc tgggtgcccg acccctcgat ccggcggtcg acctgaccag
    25081 gacggcccag acgctgcggg tcgaggttcc cgccgaactc agcagggccc tgctcacctc
    25141 ggtgccggcc accttccggt gcggtgtcga cgatgtgctg ctcaccgccc ttgcgctcgc
    25201 gttggccagc cgtcggcaca acagcgccgg agtcgtccgg ctggaagggc acggacgtca
    25261 ggaggaactc gttcccggca ccgacctgac ccgtacggtg ggctggttca ccacggtcca
    25321 cccggtccgg ttcgacctgt ccggcctcga cctcaccgac gcgatcaacg gtggcccggc
    25381 cgccgcggag gcactccggc gggtaaagga gagccggcgc gtcctgcccg atcggggcat
    25441 cggctactcg ctgctgcggt acctcaacca ggcgaccggc gccatgctcc gcgacctccc
    25501 cgccgacgag gtcggcttca actacctcgg tcggttctcc ttcgaccgtt cccggacggg
    25561 ccgcgagatg gcgtggacgt ccgcgccgga atccgccgca ctcgtggcgg caccggatcc
    25621 ggacatgccg ctgatctccg cactcgaact gaactccctg gtcgtcgaca ccgaccacgg
    25681 cgaacagcta caggcgctgt tcaccttcgc caccggggtg ctcgccaccg acgaggtccg
    25741 gcacctcgcc gacgactggc aggccgcgct gcgtggcatc cgagcacagg cggccacggg
    25801 cgcgagcggc ctgaccccat ccgacgtgcc gttggtgcgg gtgcggcagc aggacctgga
    25861 cgactggcag agccgtttcg ggcgggtcga cgacgtgtgg ccgctgactc cgctccagca
    25921 cgggctgctc taccacagcc tgctgggcga cagcgccgcc gcgtcgtacc agacccagtt
    25981 cgtcctccgg atcaacggac cggtggatcc ggcgcgtctt cgtggcgcgg cacagaccct
    26041 gctgaaccgg caccccaacc tgcgggtggc cttcctgacc aagtccaccg gcgagccggt
    26101 gcaggtggtc gtggacggcg tcgaggtgcc cttcgcgcac gtcgacctcg ccggtcaacc
    26161 gcaggccgag gagcgactgg cccggatcct ggccgaggaa cgggaggccc agttccgcca
    26221 cgacagcgca ccgctgctgc ggttcagcct catcaccctc accccgaccc aggccgaact
    26281 cgcgctgacc gcacatcacg tgctgttcga cggctggtcg ctgccgctca tcgaacaaca
    26341 gctgatgcac ctgtacgccg gcggggccga cgcgctggaa ctggtcgagc acggctatcg
    26401 cgagttcctg cgctggcact cgcggcagaa cgcggacgag gcgctcgcgg cctggaccga
    26461 ggaactggcc gacgcgacgc agcccacgct cctggcatcg gggttcgccc ccgccgagca
    26521 ggctgggacg agcaccgaga tcggccaggt cgacgtcctg ctcacccgcc aggaggcggc
    26581 atccgcagtg cgtcgggccg cggattgcgg catcacaccg aacgtcctcg tgcagggcgc
    26641 ctgggcggtc gtgctcgccc agctcaccgg aaacgccgac gtcctcttcg gcagctccgt
    26701 caccgtacgc ccgcccgaac tgccgggcgc gcacacggtc gtcgggatgt tcaccaacac
    26761 cgtgccggtg cgggtacggt gcgcgcccgc cgacagcctc gaaggcatgc tccaggccgt
    26821 acaggatgcc caggcgagga cgttggatca ctaccacgtc gggctcggcg acatccagcg
    26881 ggcgaccgga ctcactaccc tcttcgacac catcgtcatc ttcgagtcgt tcccggtgga
    26941 ccgggcggcg ttgtcgaagg ccagcgcgtc ggcggaactg accgtcaccg gcatccggcc
    27001 gttcgcgccg acgcactacc cgctgaccgt gctcgcggcg gcggatccgc tgttgagcct
    27061 gaccctccag taccaccccg acgcgcttgc accgagcacc gtgcaggcga tcgcggaccg
    27121 tttcgcccgg gtgttgcggc agttcgcggc cgacccgcgg acccgcatcg ccgccatcga
    27181 cgtgctctcc gaggccgagc ggcagctggt ggtgcacgac tggaacgcca ccgcgctgga
    27241 ggtgccgccc gagttcgtgc ccgagcagtt cgcccggcag gcggcagcga caccggacgc
    27301 ggtggccgtc gtggtggggg agcagcacct cacctacgcc gagttgagcg agcgggccaa
    27361 ccggatggcg cactggctga tcgcgcaggg aatcggcgcc gagagccggg tcgtggtcct
    27421 gctgccccgc tcggcggacc tggtggccgc gctgctggcg gtctggcagg ccggcggatg
    27481 ctacgtaccc gtggatcccg actatcccgc cgcgcgggtg cggtccgtga tcgacgactg
    27541 tgcggccacg ctggtgctgg acgagaacct gctggaccgg accgacctgt cgcgctaccc
    27601 ggcacacgcc cccgcgatcg ccgtcgcgcc cggccaggcg gcctacacca tctacacctc
    27661 cggctcgacc ggcaagccga agggcgtggt catcggccac gacgccctga ccaactttct
    27721 ggccagcatg cagcgaacgc tgcgcctgtc ggcgcaggac cgcttcgccg ccgtcaccac
    27781 gatcgccttc gatatcgcgg cgctcgagtt gtttctgccg ctcacgaccg gggcgcgcgt
    27841 ggtgctcgcc aaccgggagc acgtcgcgaa tccaccggcc atgctggacc tcgtcgagca
    27901 gaccggcgtc accgtcatgc aggcgacccc cgcgctgtgg cagatgctcg cgacgcacga
    27961 cgtgcgtcgc ctgtccggcg tacgcgtcct gaccggcggc gaggcactgc cccggccgct
    28021 cgccgagggc ctctgcgcgc acgccgcaca ggtgatcaac ttgtacgggc cgaccgagac
    28081 gaccgtctgg tcgacccttg cggacgtcgc gacctgcaag ccgccgtcga tcggtacgcc
    28141 catcgccaac acccaggtcc tgatcctgga ctcggcactg cggcccgtcc cacccggggt
    28201 cggtggagac ctgtggatcg caggggacgg cctggcccgc ggctatcacc ggcaaccggg
    28261 gctgaccgcc agccggttcg tggccaaccc gttcggccct cagggtgccc ggatgtaccg
    28321 caccggcgac ctggctcgct ggtcggagag cggaaggatc gagttcctcg gccgggccga
    28381 cttccagatc aaactccggg gattccggat cgagccgggc gacgtcgaac acgccctgac
    28441 ccggcatccc gcggtccgcg aggccgtcgt gacgatccgg gaggaccagc ccgacgacaa
    28501 gcggctcgtc gggtacgtgg tcgtcgccga ggatgccgag accccgccga cccgggagtt
    28561 gcagcagttc gtgcgggagc agctgcccga ctacatggtc ccgtcggcgg tggtcaccct
    28621 gcccgccatt ccgttgacgg cgaacggaaa gctggaccgt tcgcgactgc cccgacccga
    28681 ggcgagcagc acgaagtacc gggcgccgga atccgcccgg gaggtcgccc tctgcgggat
    28741 cttcgccgaa gtcctcggcg cggagcgggt cggcgtcgac gacgacttct tcgcgctcgg
    28801 cgggcactcg ctgctcgcca cccggcttgc cgctcggctg cggtccgacc tgggggtcga
    28861 ggtcccgatc cgcaccatct tcgccgcacc gaccgtcgcc gaactcgccc ggcggtggag
    28921 cggtctgtcg acctccgtcc ggaagcctct gcgcaggatg accgaaaggt aacagagaat
    28981 ggcgcccgtc tcgtatgcgc aacaacgaat gtggttcatc aatcggttcg agggccagac
    29041 cgcgacctac aacatcccga tcctgatccg gatgcgcgga cagatcgacc gagacgagct
    29101 gcgggctgcg ttcatggacg tcctgtcccg gcacgagatt ctgcgtaccg tctacgacga
    29161 gctcgacggg cagccgctgc aacggatcat cgagccggcc gagctgagcc tgccctggac
    29221 cgactgggga tgggtgtccc cacagcaggt ggacagcatc gtcgccgcgt cggtccgcga
    29281 gggcttcgac ctgtcggtgg acctgccgat ccgggcgtac ctgctgcgtc ccgagccgga
    29341 cgtggccctg ctcgcggtgg tgatccacca catcgccggc gacggcggct cgctcggccc
    29401 cttcacccgg gacctctcgg ccgcctaccg cgcccggctg gccggggtgg cgcccacctg
    29461 ggacgagctg ccggtgcagt actccgacta cgcgctctgg cagcgtgagc tgctgggcga
    29521 cgagtccgac ccggacagcg tcttctcgac ccagctgcgc tactggcggc aggaactgga
    29581 cggcgtctcc cggccggtcg cgctgcccgt cgaccggccg cgtcccgccc gggccagcta
    29641 tcgcggcgac aaccacggat tcgagattcc cgcggcgctg ttcgagaagg tcgagcgcct
    29701 cgcccagtcg tacaacgtga cggtgcccat ggtctttcag accgcgctgg tggtcctgct
    29761 gcaccgcctc ggcggcgacc gcgacatcac gctcggctcg ccgatcgcgg gccgcaccga
    29821 ccaggccctc gagaacctcg tgggcttctt cgtcaacacc tgggtgctgc gggtgggggt
    29881 gtgcaccggc gactcgttcg cgcaggtcct ggaacaggtc cggcagaagg ccatcgccgc
    29941 gtacgaccac caggacctgc cgttcgagcg gctggtggag ctgctgcgac ccgggcgctc
    30001 agtcgcgcat caccccctgt tccaggtcac cctcgcctgg cagaacagcg tccgccagga
    30061 actcgacctg cccggcgtca cggcctcgat ggagccggtc gccaccggca cggcaaagtt
    30121 cgacctgttc gtcaacctga tgccgaacca ttcgcgcagg tcggtgaccg tcgacctgga
    30181 atacgccacc gacctgttcg accccgccac cgtcgaggcg atcgcggcac ggtacctgcg
    30241 cgtgctggag caggtggtgg agagcccgga cctcggcgtc ggcatcctcg acgtacccgc
    30301 gatgccggcg acgcgcggcg agcggacggt cgacgccggc gaacgcgaga agatcctcta
    30361 ccgctggaac gacaccgacc gcagctttcc ctgcccggga ccgatccacc tgccgttcga
    30421 gcagcaggcc gccgcgcgtc ccgacgcgat cgccgtgcgc tggtcgggcg gcaccatgac
    30481 ctaccgcgag ctcaaccggc aggccaaccg gatcgcctgg accctcaagc gccgcggcgt
    30541 gcggccggag accgtggtgg gcgtggccgt gcggcgcggc ccgctcatgg tcgccgccgt
    30601 cctcggggtg ctcaaggccg gcggagcgta cctgcccatc ggctccacac tgccctccga
    30661 ccgggtcgcc ggcatgctgg ccgacgcgtc cgcgacgctg gtgctgacca ccgaggacac
    30721 caacaggtgg acgccaccgg atggcgtgga actcctcgac gtcggccggg ccggcctggc
    30781 cctgtcgctc gacggcgaga tcaaccccga gccggtggcg agtgccgaca acacggccta
    30841 catcatcttc acctcgggaa gcaccggaaa gcccaagggt gtcactgtgg cccaccggcc
    30901 ggtgcacaac ctgctgaact ggtgctaccg gaccttcgac ttcggccccg acgatgtgag
    30961 tctctgcgtc acctcgctgg acttcgacct ctccgtgttc gacatcttcg gcctgctcgg
    31021 ggcaggcggc gggttctaca tcgcggacgc cacccagcag cgcgatccgg agatgctgct
    31081 cgacgtcctg ctgtcggagc cgatcacctt ctggaactcg gtgccgggca cgctgaacca
    31141 actggccccg ctgctgccgc agaccgccgg cagcccaggg gtgcaggatc tgcgcctggt
    31201 ctttttctcc ggcgactaca ccccgctgtc cctgccggac caggtccgcg cggtcttccc
    31261 gcacgccgag atcatcagcc tcggcggcgc gaccgaggcg acggtctggt cgaacttctt
    31321 cccggtcggc gcgatcgacc cgcagtggcg cagcattccc tacgggcggc ccatcgacaa
    31381 cgcgcgctac tacgtcctcg acgagaagct ggagccgtgc gcggtcggtg tggagggcga
    31441 cctctacatc ggcgggccgg tgatcgctct cgggtacgtg aaccgtcccg acctgacggc
    31501 cgagcggttc atcgccgacc cgttcggcgg ggttcccggt cagcgcatct accgtacggg
    31561 cgaccgcgcc agcttcttcc cggacggcaa catctgtttc cttggtcgcg ccgacggcca
    31621 ggtgaaggtg cgggggttcc gcatcgaact gggcgagatc gagtacgccc tcggccgcca
    31681 cccggcggtg cgccagggta tcgcgatcac ccgccgggac tccgtcggtg acctgcggct
    31741 ggtcagctac gtcctgcccg atttggacac ggtggagagc gtggtcgccg ccgacgaaca
    31801 ggtccgcgaa tggcaggaga tctacgacca gggctacctg gaggtcaccg accaggattt
    31861 cggcgacgac ttcaacctct gggtgtcgag ctacaccggc gagcccatcc cggtcggcca
    31921 gatgcgggag tggcaggacg ccgccgtcga ccggatcctc agcttcacgc cgcggcgcgt
    31981 actggaggtg ggtgccggaa ccgggctgct gctcgcgcgg gttgcgggca gcgtggaggc
    32041 gtactgggcg accgacttct cggagccggt catcgagcgg ctgggccggc aggtgaccga
    32101 ggcgggctgg gccgagcggg tacggctgct gtgccgacgc gcggacgacc tggacgggat
    32161 cccacggatc ttcgacaccg tagtgctcaa ctcggtcgtg cagtacttcc cgaacgagcg
    32221 ctacctggag caggtgctcg acggcgtctg ggcgatgctg gagccaggtg gccggctcgt
    32281 gctcggcgac atccgccggg cccgctcgct gcgcgccttc caggtggccg tgcagcaggc
    32341 caagcacggc aacctcccgc cggcgcaact gcgcagcgcg gtcgaacagg gcctgctcct
    32401 ggagaaggaa ctggtcatcg acccggagtg gttccagcgc tgggccgagc gcgcgggcgc
    32461 ggccggcgtc gacgtgcgcc tgaaggaggg cgcgttccag aacgagttga cccgccaccg
    32521 ctacgagatc gtggtgcaca agccgggcac aacggaggcg ggccggccct acgcggtgga
    32581 taccgtcccg cgcctggagt ggaacggcga cctggacggc ctggccgagc gcatccgcac
    32641 gctgggcggg ccggtggtgc gcatcgccgg catccccaac gcgcgcgtcg cgcaggaggt
    32701 ggcggcggcg cgcgacctgg ggctggagga gtccgagccg ccgacgtcgg tgccggtgga
    32761 cccgcacgag atggcgacct gggccgcccg gcagggctgg tcgatcgcgc tgacctggtc
    32821 cggaagcgcc gtcgaccagt ttgaagcagt cctgttcacc gacgctacga ccgagcaccg
    32881 ggcactgtcg ggcacctacc tcccggtggc cgccgccggc acctggatca acgacccggc
    32941 cgccgcggcg ggcatcaccg cactcccggc ggtcctgcgg gagtacctgt cgaagacgct
    33001 gcccgagtac atggtgccat cggcgatcgt gccgatcggc cgggtgccgc tgacgccgaa
    33061 cggcaagctg gaccgggcgg cgctgccggt gccggagtac gccgccgcca gtcgcggccg
    33121 gccgccgtgt acctccgagg aggagtcgct ctgcgagatc ttcgccggcg ttctcgggct
    33181 cgaccgcgtc ggcgtggacg acaacttctt cacgatcggc ggccactcgc ttctggcgac
    33241 ccgggtggtg agccggatcc gcgccgcgca cggtgtcgag atcccgatcc ggacgatctt
    33301 cgaggcgccg accgtcgccg aactggtggc ccatttgacc ggccagcgga cggtccggcc
    33361 gccgctgcgg ccgcagccgc ggccggaccg gctcccggtt tccttcgccc agcaacggct
    33421 gtggttcatc caccgcttcg aagggccatc gccgacctac atcattccgc tctccatgcg
    33481 tctgcgcgga aaactggacg tgcccgcgtt gcggcaggcg gtgcacgatg tcgtggtccg
    33541 gcacgagtcg ctgcgcaccg tcttcgacga ggtggacggg gcaccctacc agcgggtact
    33601 cgacccggac gggttggcga tcccgtggca ggagcacgag gtcaccgagt ccgcccttca
    33661 ggaggcgctg cgcctggagg cacgtcggcc cttcgacctg gccgcggaga ttccggtacg
    33721 cgccgcgctg ttccgcgtcg gcgagcacga cgcggtgctg ctgcttccgc tgcaccacat
    33781 cgcggccgac ggctggtcgc tggggccgct ggccgaggat ctgaccgccg cgtacaccgc
    33841 caggtgcgac gggcagcgac cgcaatgggc cgcactgccg gtccagtacg ccgactacac
    33901 gctgtggcag cgtgaccttc tcggcggcga tgacccacac agtctgtacc ggcggcagtt
    33961 ggactactgg acggggcaac tcgccggact gccggaatcg ctgcaactgc cgacggaccg
    34021 ggcccgaccc gccgtcgcgt cgttcgccgg cgaggtgctg cccgtagaac tcgacgaatc
    34081 gctgaccgag gacctccgca agttggccct gcgtaccggt accaccgtgt cgatggtgct
    34141 ccaggcgggt ctcgcggggc tgctcagcaa gctcggcgcc ggtaacgaca taccgatcgg
    34201 gtcgccgatc gccgggcgga cggacgaggc gctcaaccga ttggtgggct tcttcgtcaa
    34261 cacctgggtg gcgcgcgtcg acaccagcgg aagccccagc ctgatcgagc tggtggaccg
    34321 ggtacgggag gtgagcctcg ccgcctacga ccaccaggac atcccgttcg agcacctggt
    34381 cgaggcgctg aatccggtgc gctcgaccgc gcatcatccg ctgttccagg tgtgcctggc
    34441 ccttcagaac aacgtgcagc cggccttcga cctgcccgga ctgaaggtgt cccacgagcc
    34501 ggtcgacatg ggcgtctccc gtttcgacct gttcttgaat ctgatggagg agaccaccgg
    34561 cgaggggacg agccggatcg ccggagtcgt cgagtacgcc acggaactgt tcgaccggga
    34621 cacggtcacc gggctgctgg agcgctggcg gcgcctgctg cggcagtggg tcggcgctcc
    34681 ggacgccccg atcgacgcgg tggagatcct caaccgggac gacctggccg cccttgagcg
    34741 ctggaccggt cgcgctcgcg gcaccgatcg tgtcgtcggg acgattcccg agcgtttcgc
    34801 cgccgtggtg gccgagcagc cggaggctgt cgccctggtg gccgccgacg gcgaggagag
    34861 ctggacgtac ggcgaactcg accggtgggc caaccgcatc gcccaccatc tccacgcgcg
    34921 cggcgtcggt cggcagcacc gggtggcgtt ggtcatggag cggtccccgt tgctggtcgc
    34981 ggcggtgctg ggcacgctca aggcgggcgc ctgttatgtg ccggtggaac ccacctggcc
    35041 gcgggcccgg atcgacctcg tgctcgccga cctcgatccg gccctcgtga tcgacgagcg
    35101 gctggccgag gaggacctga ccggctaccc gacgcgcccg ctggacaccg ccgacgtcgg
    35161 cggggagcac ctcgcctacc tgatgtacac ctccggctcc acggggacgc cgaaaggtgt
    35221 cgaggtgagc catcgcaacg tgctcagtct cgcgctcgac ccgtgctggg ccgatgctga
    35281 ccaccagcga gtgctggtgc atgccccgcc gaccttcgac gcatcgacgt acgagatgtg
    35341 ggtgccgctg ctgcacggcg gagcggccgt ggtcgcgccg ccgggaaagc tggacgcggc
    35401 ccgactggcg acgctcatcg ccgagcgggg cgtaacggcg ctgtggctgc cggcgggcct
    35461 gttcgatcta atcacgcagc atcacccgaa gagcttcgtc caggtacgcg aggtgtgggc
    35521 cggcggcgac gtactgtccc cggcggccgt gcgacggctg gtacgcgacg acggcacgct
    35581 caccgtcgtg aacgggtacg gtcccaccga gaccaccacc ttcgcggccc ggtaccggat
    35641 gtccgcaccg gcgcggtgca aggacccctt gccgatcggc gagccgatgg cgggcagccg
    35701 cctctacgcc ctcgacgacc ggctccggca ggtgccgcag ggcgtcatcg gcgaactcta
    35761 cgtcggtggc gacggggtgg ctcgcgggta cgcgaaccat cccccgctga ccagcgaacg
    35821 attcgtcgcc gatcccttcg gacgcccggg cgagcggatg taccgcaccg gtgacctggt
    35881 ccggtggaac cacgacgggc aactcgagtt cctgggccgc gtcgacgagc aggtcaagat
    35941 ccgcggtttc cgggttgagc cgggagagat ccgagcggcc ctccggaaac gggacggcgt
    36001 ggcacaggcg gtggtggtcc cccgtacgga ccgactcggc gagcggcgcc tggtggccta
    36061 cgtggttccg gaggtgccgg cgggcgcgga cgaagactcg accgaacatg tcgagaagtg
    36121 gcgcgccatc tacgactcga tgtacgacga gaccgaggcc gacgctaccg agatcggcaa
    36181 cgacttcacc gggtggaaga gttcctacac gcgcgacaac atcccgctgt ccgagatgcg
    36241 ccggtggcgc gactccgtcg tcgaggaggt ccgcggtctg cgggcgcgcc ggatcctgga
    36301 gatcggggtc ggttcgggcc tcctgctcgg gccgttggcg ccggaagcgg aggcgtactg
    36361 gggcaccgac ttctcgttgc cggtcatcga gcgcctcgag gtgcaggtcg gcaccgatcc
    36421 gtgcctgaag gagaaggtgt cgctgcggtg ccagcacgcc gacgtcgccg acggactgcc
    36481 ggtgaagtac ttcgacaccg tcatcctgaa ctccgtcgtg cagtactttc cggacgccgc
    36541 ctatctctcc cgggtactgg acgtcgccct ggaccggctc gcgccgggtg gccggatcct
    36601 cgtcggtgac gtccggaact acggcaccct gcgggagttc ctgacggccg tccatcacgc
    36661 gcaacacccg caggacagcg cgtcggccgt ccgggcggcg gtcgagcgtg ccgtcctggc
    36721 cgagaaggaa cttgtcatcg atccggattt cttcaccgag tgggcacgga cccggcccga
    36781 cgtcgtggcc gtcgacatcc ggctgaagcc gggcgcggac cagaacgaac tcacccggca
    36841 ccgttacgag gtcatcctgc acaagcagcc gagccaacca ctgcgcctcg cggacgtgcg
    36901 gacggcgaac tggggctcgg aggtgcccga cctgtccggg ctggagaccg cactggcccg
    36961 gcacggcggt cgcctccggt tggcccggat cccgaacgcc aggctggtga gcgaggcggt
    37021 ccagtgcggc gtgcccacca acgtaggcgg cacgcccctg gacccgcacg agttggcgag
    37081 ctggggaggg cagcggggtt actcggtcca ctgcacgtgg tcggcggagg cgcccggctg
    37141 gttcgaggcg gtgatcatcc cggtcgacag cgggcactgc cgcgacggtg tgtaccggcc
    37201 ggtggggccc cggccacggc agttggtcaa cctgcccgcc gcggcgcgcc gggtgtctcg
    37261 gctgccctcg tggctgcgcg aggaactggc ggcggagctg ccggagcacc tggtgccggg
    37321 cgacatcgtg gtcatggaac gactgccgtt gaccaccaac gggaagatcg accacagcag
    37381 acttccggag gtggagcagg ccgaccggga gtacggctcg ccgcgcacac ccctggaggc
    37441 ggaactggcc ggtctcttcg ccgaggtcct cggcgtggac cgggtgggca tcgaggacga
    37501 cttcttcgac tgcggcggta gttctctcca ggtcatccgg ctcatctggc ggatccgcgc
    37561 ggagctgggc ttcgacattc cggtcagaac catcttccag catccgaccg tggccgaggt
    37621 cgcggaacat ctggcggccg gcagggagga cgtcgagttc gacgacccct tctcggtggt
    37681 gctaccgatc cggaccgacg gggaccgggc accgatctgg ttggtgccgc cgggtggcgg
    37741 actctcctgg gcctatctcg gcttcgccca gcacctggac cgctcgcgcc ccatctacgg
    37801 cctccaggcc cgtggatttg tcggagaccc gcgggcgacc tcgatcgaga gcatggtgga
    37861 cgactacgtc gaccagatcc tgcgggtcca gccggaaggt ccctacaacg tgctgggttg
    37921 gtcgctgggc ggcccgatcg cccaggcggt ggccgccgaa ctccagcgcc gggagtgcga
    37981 ggtggatctg ctggccgtcc tcgactcggg tccggcgagc tacttcgccg acttccagac
    38041 tcccgacgag aagttggtgc gcaggtacct ggcgcactac atgggccatc tcgcgggaat
    38101 ggcggagttc gagtcgctcg tgcagacatc caccaccctg ttcatcgagc acacggacct
    38161 gatgacgcaa ttcacgtcgc cgccgttccg tggcgatctg atcttctttg ccgccctcat
    38221 cgaccagggc acccgggaac gacggcaact cgaggtggaa ctggacgtcc aatggcggga
    38281 atacaccgag gggaccgtgc ggcgcttcga catcgaatgc gcccacaacg aaatgatgtg
    38341 gcccgagaac gcggccatga tcagccgtat cgtcaacgag atcatcgatt cggcccgata
    38401 accgcttccg ccctgacctg gagcggacgt gacaactacg gaggaaagat gagcgtcaac
    38461 ccgttcgatg acgaggacgg cgagttctac gtgctggtca acgacgagga gcagcactcg
    38521 ctgtggccca ccttcggtga cgtgcccgac ggctggcgaa tcgtgttcgg gccggccggc
    38581 cgagcggaga gcgtggcata cgtggaggag aactggaccg acatgcggcc caagagcctg
    38641 cgtgaggcga tgtcggcagc atgacgtacg tcgtgggctc gcaggcagac gcgtccgcct
    38701 gcgggcccac gattttgaac ttccgcgacg ccggtggcgg aaggtgcgta cagaagtctt
    38761 cacaggatgt ctaggtatag aactgggatg tggcaagccg gagatcgccg ggggagtgat
    38821 cagcccgggt caccccgccg gctccgcgtc gcgcgccaga cactttggag gccccatgac
    38881 tgttgcgtcg cccaggcaga gccgagaaga cctatcgctc gtcccggaca cccatgacgt
    38941 catccgcgtg gtcggggcac gggagaacaa cctcaaggac atccgactgg agatcccgaa
    39001 gcgccggctg accgtgttca ccggtgtctc cggctcgggg aagagttccc tggtgttcga
    39061 cacgatcgcc gcggagtcac agcggctgat caacgagacc tacagcgcat tcgtgcaagg
    39121 gttcatgccc acgctgtcgc gccccgacgt cgacgtgctc gatggcctca ccacggcgat
    39181 catcgtcagc caggagcgga tcggcaacaa tccgcgttcc accgtgggca ccgtgacgga
    39241 cgccaacgcg atgctgcgca tcctgttcag ccggctcggc gagccacgac tgggctcccc
    39301 gcggtcgtac tcgttcaaca ttccctcgat cagcgtcgcg aacgcggtca ccgtcggcca
    39361 agggagccgg gcggtcgagg agcaacgcgg cttcgacgtc gccggcggca tgtgcccacg
    39421 ctgcgaaggt acggggtcgg tcaacgacgt cgacctcacc cagctctacg acgccacgaa
    39481 gtcgctcgac gagggtgcca ttcgggtgcc cggttaccag gtcggcggct acaaccaccg
    39541 gctctacgcc ggttccgggc tgctcgaccc cggcaagccc gtcgagaagt acaccgagaa
    39601 ggagctcaac gacttcctcc accgggaacc gacccggctg aagatcggcg actaccacac
    39661 gaactacgaa gggctggtcg caagggtcca gaagtcgctg ctcaccaagg acatcgaggc
    39721 gcttcagccg cacgtacgcg ctttcgtgga gcgtgcggtc acgttcacgg cgtgcccaga
    39781 ctgcggcggt acccggctca acgagcaggc ccgggcatcc aggatcaagg gcatcaacat
    39841 cgccgacgcc tccgcgatgc agatcaacga cctcgccgaa tgggtccgcg acctggccga
    39901 gccatccgtc gcaccgctgc tggccacgct cctgcacacg ctcgactcgt tcgtgggtat
    39961 cgggctgggc tacctctccc tcgaccgggc ctccggcaca ctctccggcg gcgaggcaca
    40021 gcgggtcaag atgatccgcc acctcgggtc accgctcacc gacgtcacct acgtcttcga
    40081 cgagccgacg atcgggcttc acccccacga catccaacgg atgaacaaac tcctgctgcg
    40141 gctccgcgac aagggcaaca cggtgctcgt cgtggagcac aagccggaga ccatcgccat
    40201 cgccgaccgc gtcgtcgatc tcggtcccgg cgccggcacc gcaggcggca ccatctgctt
    40261 cgagggcacc gtcgcggaac tgcgttccgc cgacacgctg accggccgcc atcttgacga
    40321 caaggcgtcg ctgaaggaca gggtgcgtac cccgtcgggc tcgctcgagg tccggggcgc
    40381 gagcaaacac aacctgcgag acgtcgacgt cgacatcccg ctcggcgtgc tcgtcgtcgt
    40441 gaccggcgtg gcaggctccg gcaagagctc actgatcgaa gggtcggtat cgggacgcga
    40501 cggcgtggtc acgatcgacc aggggtcgat caagggctcc cgtcgaagca accccgccac
    40561 ctacaccggc ctcctcgatc ccatccgcaa ggcgttcgcc aaagccaacg gcgtgaagcc
    40621 ggcgctgttc agctcgaatt ccgagggggc ctgtgccacg tgcaagggtg caggcgtcat
    40681 ctacaccgac ctggcgatca tggcgggcgc ggcgaccacc tgtgacgact gcgagggcag
    40741 gcggttccag gacttcgtgc tccagtaccg tctcggcggt cgcgacatca gcgaggtgct
    40801 ggccatgtcc gtggccgagg ccgggcgttt cttcgctgcg ggtcaggcac gtacgcccgc
    40861 cgccgtcgtc atcctcgaac ggctcgccga cgtggggctt ggctaccttt ccctcggcca
    40921 gccactcccc acactctccg gaggcgagcg gcagcggctc aagctcgccg cgcacctggc
    40981 tgacgaaggt ggcatcgtcg tgctcgacga gccgaccacc ggcctgcacc tcgccgacgt
    41041 ggagcagtta ctcggtctgc tcgaccggct cgttgacgct ggccggtcgg tcatggtcat
    41101 cgagcatcac caggcggtca tggcccacgc cgactggatc atcgacctcg gtccggccgc
    41161 cggccacgac ggcggtcgtg tcgtcttcga aggctgcccg gccgacctcg tagccagccg
    41221 cgccaccctc accggcgaac acctcgcggc gtacgtaggg gtctgacggc ccgcctgaca
    41281 cggtttccgg ccgcctgccg tggcggccgg tcaccgctcg tacaagcacc cgctctgtcg
    41341 gcctcggccc acgcgtgcga tggcatccca tggcggtacc cgaccgccgc ctcaggctcc
    41401 atcctgccct gaccaggccg ttctccagca cgcggcgatc ggttcgggcc gatccgggta
    41461 gcccggcaca ggtgtttctg ctgtccccgt acctgaccga acccagctct tcgtggccct
    41521 ggcgaagttc tttcatcctt gtggcatgcg tgttgcgtga ccccatggtc gcgttgagta
    41581 ttgggaatcg taattggata tctcgcctgc ggggggatgc ggtgatggag gcgactggcg
    41641 ttgcggctgc gcgggtgcga gcaccggccg agccggcccg tcgcgttcgg ggtcgaggtc
    41701 gtcatggaca cacagccggg gcgatgccgc cacggatccg tgcccatgac gctctgacag
    41761 attcgttgac cgcgacccgt cgccgatggt gacgggagca gggcctttcg cgagatgttt
    41821 tgggggattt gcttgtgggc ggtcggaact ccgatgtcgt cttcatccgc tggcccgctc
    41881 aggcggacct gagaacccgg tgccggaagg agggagtgcc gcggctgctc gtcgtggagg
    41941 gcggtgcgca gccgccgatc agcaatgacc cggtcgagga ctgggtccgg ccgccggtgt
    42001 ccaggaacga cctggaggca cgggtcaagg cactacaaca acgcttcaac agccgacggc
    42061 tgccgaccat cgactctacc gggacgttga ccttcggccg tcactcgatc gtcatctcca
    42121 acacccaggc ggagctgatg cggctgctca tcgaacgctt cggcgaagtc gtgtaccgca
    42181 tcgagttcgt gcagtgcctc gccatccgga cgcccgcgct gaacagaaac tcgctcgacc
    42241 tgcacatcat gcggctgcgc cgccggctcc taccgatcga cctggcgatc cggaccgtgt
    42301 ggggtcgggg ctacatgttg gcgtatgcgg cctccgccga ggccatcatc agaaacgcca
    42361 gcggcatgtg atgatgcctg ccgaaaacag ctcaaatcgc cgtaccgtcg agctgaaggt
    42421 tgcggtgcgt ggctaccgcc ggtccggcgg aagcagcgag gagcgcgtcc agcgcgccga
    42481 gccggccctc gcggacgaac cattcccggc cgtaggctgc ggcgaagcat gaggggtcga
    42541 ggtctgccgc cccgacctgg ctggcgtgcg tggccatcgc ggccatcttc gcgagcaaat
    42601 cggcaccttc cgcgtcgaca gcgagcgaga tccgggacgc cggcaccccc atgtccgtca
    42661 ggtcgccggc agcacgctgc aacacgtgac gtggccccgc gcgcagagct gaggcatcca
    42721 cggtggcctg gtatcccgcc agctgaaggc tgcgggtgac cagagcgccc acccggtgca
    42781 cctgaacgtg gtccacgtgc cggtagatgc cgccgggatc atagtgaacc agcgtggtcg
    42841 caccctcacg gctggcgatc cgggccacct gtcgggcgac cctcgtggcg gacgccgcgc
    42901 cgagggtgcc ggcccggtac gggccgccgt gcgcaccgga atcggcgtag cccagcacct
    42961 ccaatctggc tacgccgagc aggtcacagg cacgttcgag ttcggcgaga cggcggctgc
    43021 gcaaactctc gccgcgtgac aacggcacgt gtggaacacc ggcggcacca tcggtggcca
    43081 tgacgaggat cacgcgggcg ccagcgtcgg ccaggcgacg catggtcagc ccggtgaaga
    43141 ttgcctcgtc gtccgggtga gcgtgcagga cgatgaccgt gtgcgaggag agcatgatgt
    43201 gatccctttt gatcgcggcg gttgagcacg gtcgcgacga cagcgcgtcc gccacgcgct
    43261 gcgacgcacc ccgctcgaac cggaagccga agaagccgac gtgtggtgcc cgcgcgatgt
    43321 gctgcgcgga gaacggctag gtcatagcta ccgcacccca ctcgcgtggt ggtacgtcac
    43381 ggaggtgtct cgtgaactcc cacaagtgac cttcgaggtc acggaccagg tactggcgca
    43441 gtccccacgg cttgtcctgc aggggctgca cgatgtcggc acctgccgct gtggagcgca
    43501 tgaagtgctc gtcgacgtcg gagacccaga cgatgacctg cttgcaggtg tgcccgccgg
    43561 cgcagctgac cgtgtagggc tcgccggtac gccggaccat gacgatccca ccgccggtgt
    43621 ccagatcggc gtgtcggatg gtcccgatgg ccggctgccg gagcagcagg cggaacccga
    43681 agacccgtac cagccagtcg acagcacgat cggggtccgt gtaggcgagt tcgacgacca
    43741 cgtgagggaa gccgcgggcc gggtcgtaca cagagtctcc ttcgttcggc gagcagcttg
    43801 ccgacgtcaa cggttcgacg tcaccgtttc gggacagggt cttcggatgt cggaagttct
    43861 cgacatccct gtcgaggcag gctacccacg ttttgagaca ccagggcccg cggcgaagca
    43921 tctgcgaaag aggtgccaac cgtcccatcg gacgccgccg ctcgcggtgg aggcggtccc
    43981 ggccgccagg gactgcaaga cggtccggac gtcacggtgc gtgccggcgt gcagttctga
    44041 tccggccgat ctgagggcga cggttgattg gttggcagga atcaagccgg agagtgtcgg
    44101 atctggcgga tccagccggt ccgcgacccc tcgcggaacc cgctgttcca ggtgggcctg
    44161 caactgctgg gcagcgccac ccagagcacc gagccgaacc tgcccgggct caccgtcacc
    44221 tcgctggacg ccaacccggg cgggcacccg ttcgacctgt cgatcacctg caccgagagc
    44281 cccgaccagc tgcggctggt cgccgactac tcggtcgacc tgttcgacga gccgcggatg
    44341 gcgcggctgc tgcggcacct ggaacgggtg ttgcggaccg ccgtcgacgc ccccgacacc
    44401 ccgctgtcgg cgctgccgtt gctcgacgag gaggagcaaa cgctgctgct gcacacctgg
    44461 cagggaccgc agggggagcg cgcccgcgaa ccggtgcacg tgcagatcgc gcggctggcc
    44521 gccgaacgac ccgacctggt ggcggccacc ctgcacggtg ccgagctgac ctacggcgag
    44581 ctggatcgcc gcgccggggt gctggcgcac cggttccggg cgctcggcgt gggccgggac
    44641 gacatcgtgg cgttgctgct ggaacggggc ttcgacctga tcgtcggcat ggtcgccgcg
    44701 cagaaggccg gcggcgcgtt cgtggtgatg gacccgggcc acccggtacg ccgcatcgag
    44761 ttcatcctcg aagacaccgc ggccaaggcg gtggtcaccc gcagcgcgct ggccgaccgg
    44821 ctgcccgagg gtgccgccgc cacgccggtg ctcgtcgaca cggagtggga cgagttgtcg
    44881 gcggcggccg ccggcgcggc gccgctggac gaactggccg acgagaactc gctggcctac
    44941 gtgctctaca cctcgggctc gaccggcaaa cccaagggcg tgatgatcga gcatcacgca
    45001 ctgaacacgt tcctgctctg gctcggcaac atcttcgact tcggccccgg cgaccggttg
    45061 ctgcaacaca tggcgcccat cttcgacttc gccgagggcg agatcttcac cgcgctgacc
    45121 cgtggcgtga cgatggtctt cgtaccggag gaacaccgca ccgacccgga cgtgatcggg
    45181 cagctgctgg tctcggagag gatcacctac atcggcggac cgccggccat cctgggccgc
    45241 atcccgccgg gcagctatcc cgacctcaag tacatgatcg ccggaggtga ggcggtcacg
    45301 ggtgatctca tcaaccgctg gaacaccccg ggtcgccggt tcatcaacgg gtacggaccg
    45361 accgaggcgg ccgtcggctg catcttctac gagtgcgagc accgcacctg gatcggccaa
    45421 ccgccgatcg ggcgggccat gcccaaccgg gtcgcctacg tgctggaccg gtggaacaac
    45481 ctgcaaccgg tgggggtgcc cggtgaggtg atcaccggcg gggagggtct cgcccggggc
    45541 tacctcaacc ggccggagtt gaccgccgag aagttcatcg acaacccgta ccggccgggg
    45601 gagcggatgt accgcaccgg cgacctgggc gtgtggaccg aggacgggca gatccagttc
    45661 ctcggccgca tcgacaccca ggtcaagctc aacgggctgc gcatcgagct ggaggagatc
    45721 gagtcgacgc tcaccgcgca tcccggcgtc gccgaggcgg cggtggcgct gcgcgaggac
    45781 agccccggca gcaagcgcct ggtcggctac gtggtcccgg ccggcgcggc ggcaccaccg
    45841 accgaggaac tgcgcgagca cctgctcgcc gacctgccgc cgtacatggt gccgcacgtc
    45901 ttcgtggccc tggacgtgct accgctgacc agcgtcggca aggtggaccg caaccggctc
    45961 ccggttcccg aggagaccgg gtcggccgag gtggagctgg tcgcgccgcg caccccggag
    46021 gaggagcggg tcgccgagat cttcgccgcg gtgctcggtg tcgagcgggt cggcgccgac
    46081 gcgaacttct tcgagctggg cggcaactcg ctgatggcgg cccgggtgct gtcccggatc
    46141 gccgaactcg gcggggccag cgcgaccatg cgggacttct acaccaagcc gcgggtcagc
    46201 gagatcgcgc agctgctcgc cggaacgccg tcgagcaccg acccggcgac cccgaccgac
    46261 gcggcaccgg tggccgacca gacccgggcc cggttggagc aggagatcgc cgacctggaa
    46321 cagcggctac gggccgcgcg ggcggccctc gccgggcagg acggtccggt gtccggcggg
    46381 cacgagggac agcggctgcc gctgtcaccg acgcaggagc agctgtggtt cctcgaacag
    46441 ctcgcacccg gccagccgac ctaccacatc ccggtgccgg tacggctcac cggaccgctc
    46501 gacgtcgacc tgctcggtcg ggcgctgacc gccgtggtgg cccgccacga ggcgctgcgc
    46561 accacgttcg gcaccgacga cgacaccccg taccaactgg tgtcacccgc cggtgaggtg
    46621 ccgctgccgg tgcacgagct ggacgcgacg gcagccgacg accgggagca ggcgctgcgc
    46681 gtcgagctgg aacgcgacgc caccgaaccg ttcgacctgg gtcgcgacct gatgctgcgg
    46741 gcccggctga tccgcctcga cggccaggag cacgtgctca gcatggtgtt gcaccacatc
    46801 tgcgccgacg gctggtcggc cgggctgctg gtgcgtgatc tcgccgagct gtacgacgcg
    46861 ttgcggcacg accggcagcc gcagctgccc gccctgcggt tgcagtacgc cgaccacgcg
    46921 ctggcgcagc gccggcagct cgacgccggt gacctggagt cgcagttggc gtactgggcg
    46981 cggcagctgg ccgacgcgcc catcctggac ctgcccagcg accggccccg cccggccacg
    47041 gccaccaacc gtggcgccct gctggtgcgt cggatgcccg ccgacgtgct ggagggcctg
    47101 cgccgggtgg cccagcagga gcaggccagc acgtacgcgg tgctgctcgc cggcttcaag
    47161 acggtgctga tgcgctacac cggcgtcgac gacgtggtgg tcggcaccgc cggcgccggt
    47221 cgcggccgtc cggagctgga ggatctggtc ggtttcttcg tcaacatgct ggccctgcgt
    47281 accgacctct ccggcgaccc gagcttcggt gaggcggtcc gccgcaccat gggcaccctg
    47341 ctggccgcct gggaccacca ggacgcgccg ttcgagcggg tcgtcgggcg gctcggtcga
    47401 cgccgcgacg ccagccgcaa cccggtcttc caggtctcca tcgatctgct cagcggcgac
    47461 ttggtggatt tccggttccc cgggctggcc gccgagttcc tcgacgtcga tcccggggtc
    47521 tcccgcttcg acatggcgat caacgcgtac gaggagaccg acggcatcac cttccggatc
    47581 gagtacgcca cggacctgtt cgacaccgcc cggatcgagg cgatgttcgg ccacctggag
    47641 cgggttctgc gggccgccgt ggcggcaccg cagacgccgc tgtcggccct gccactgctc
    47701 gacgacaccg agcgaaccga actgctggcg ctggcccagg ggaagcgacg gccccaccgg
    47761 ccggcgaccc tgccggagct gttcgcggcg agcgtggccc gcaccccgca ggccaccgcg
    47821 gtcatcgccg ccgagggcac gctgagctac gccgaactcg acgagcgcag ccgtcggctc
    47881 gccgcgcggc tgcgcgccgc cggagtgggc accggggacg tcgtgccggt gctgctggaa
    47941 cgcagcctcg cggaggtggt gagcgtgctg gccgtgctgc gggccggtgc cgcgtacgcg
    48001 ccgatggacc cggccgcgcc gccgagccgg ctggccttcc aggtgcgcga caccggcgcc
    48061 cgggtggtgg tgggcgaccc gacgcggctc gacacggtgg tcggggtgac catcgtggac
    48121 ccggcggcgg agctgccgga ggcggccgac gagccgtggc tggccgagct gacccccgct
    48181 tcgctggcgt acgtgctgta cacctccggt tccaccggcg agcccaaggg cgtgctcatc
    48241 gagcacggca tggtcgccgg ctacctggag tggatggtgc cggacttcgg cgtcgagcca
    48301 cggtcccgga tgatgcactg ctgcgcgccg gtgttcgacc tggccgtcgg tgaactgttc
    48361 ggtgccctca ccgccggtgc gaccgtggtg gtggccggtc acgacgacgt gcaccgcccg
    48421 ggcgcgttga ccgcgctggc ccgcgagacc ggcgcgacgc acatcttcac cactcccacc
    48481 gtgctgggtc tgctcgatcc ggccgaactg ccgcaactgc ggtcggtgat gatggccggc
    48541 gagccggcgc cgccgtcgct ggtggccgcc tggcacgtcg acggtcggcg ggtgctcaac
    48601 ctgtacggcc cggccgagac cacggtgggc tgcacctggt acgagtgccc ggccggcacc
    48661 gcacccgcgg cgacggtacc gatcggtcgt ccgatgccga accggcgggt gtacgtcgtc
    48721 gacgacagcg gcgacctggc gccggtcggt gtgcccggtg agctggtcgt cgccggcaac
    48781 ggggtggcgc gtggctatct cgaccgaccc gagctgacgg cctcggcgtt cggcgccgac
    48841 gagcgggccg gggagggacg ggcgtaccgc accggtgacc tggcccggtg gaaccgggac
    48901 ggccagttgg agttcctcgg ccgccgcgac gggcaggtca agctgcgtgg gctgcgggtc
    48961 gagctgggcg aggtcgagca tgccctgcgc acggcggccg gcgtgtccgg ggccgccgcg
    49021 gcggtgcacg gcacgggcgc cgaggcggtc ctggtcgggt acgtggtcgg cgagttgtcg
    49081 gacgacgacg cggaggcgct gcggacgacg ctcgccggga agctgcccgg gtacatggtg
    49141 cccaacgtgg tgctgcgcct gccgcagctg ccgctgaccc gtaccggcaa ggtggaccgc
    49201 aagcggttgc ccgcgcccga gtccggtgcc gggcaggcgg cgtacgtgcc gcccggcacc
    49261 gacgacgagc ggctcatcgc cggggtcttc gccgacctgc tcggtctgga acgggccggc
    49321 cgcgaggacg agttcttcct cagcggcggc aactcgctgc aggcgatccg ggcggtgggc
    49381 cggctcaacg acgcactcgg tgtgccgctg accgtgcggg acttctacgc ggcaccgacc
    49441 gtcgcggccc tggccgagct ggccggacgc cgacgggccg ccgagcaggc ggcgcagtgg
    49501 caactgctcg acgagatcga gcagctcagc gacgacgagg tggaacggct gctggcggcg
    49561 gactgatcgc cggtcgcgtc cgcgggcccc gccgccgtgc gcggcggggc cggcggtgtc
    49621 ctgaaaggag tgagatgtcc gacgagacct tcgacggcag ggtagcccga ctggacgagc
    49681 gccggcggct gctgctggaa cggatgcggc aacagcgccg gcagccaccg gcgacgatcg
    49741 gcgcccgccc ggccggcgac gagcgggtgc cgctgtcgcg ggcccaggaa cagttgtggt
    49801 tcctcgccca gctcgcgccg gccgagccga cgtacaacct ggtgcaggcc tcgtacctga
    49861 ccggcgaggt ggaccccgcc gcgctgcggc gggcgttgga cggcgtggtc gcccagcacg
    49921 aggcgttgcg cacggtcgtg gagagcgtcg acggcgtggc gtaccagcgg gtgctgccgc
    49981 cggggccggc cagcctggtc gtcgacgacg tgtcccggct gcccgaggag cagcgccggc
    50041 cggcggcgct caccctgctc cagcagcagg aggtgcaccg cccgttcgac ctggccaccg
    50101 gcccgttgtt ccgggcccgg ctggtccggc tcggtcccac cgagcacgct ctcgccgtcg
    50161 cggcgcacca catcgtggtc gacggctggt cgatgggcct gatcctgcgg gagctggccg
    50221 ccgcgtacga cgccgaccgg cacggcacgc gagcgcggct ggacccgccc gccctccagt
    50281 acccggactt cgcccgctgg cagcatcagc agctggccac cgccgaactg gacaaccacc
    50341 tgaggtactg ggcgcagcgg ctggccgacc tgcccaccct ggaactgccg gccgaccgac
    50401 cccggccgac caccgcgtcg ttccggggtg cgctgctgga gcaaccactg gatccgcagc
    50461 tgcacgccgg ggtgcaggcg ttggccaagg agaccggcgc gagcccgttc atggtgctgg
    50521 tggcggcctt cgcggccatg ctcgcccgct acaccggcac cgacgacctg gccgtcggca
    50581 ccaccttcag cgggcgcagt cgtccggagc tggagagtgt ggtcgggttc ttcgccaaca
    50641 tgggggtgct gcgtctggac acctcgggcg accccagttt cgccaccctg gtcgaccggg
    50701 cccgggacac ctgcctgggc gcgtgggagc accaggacgc cccgttcgag cgggtggtgc
    50761 agcgactcgc cccaccccgc gacccgggcc gcaacccgct gttccaggtg gccgtgcagc
    50821 tgctggacgg ctccacctgg ggcggaccga cgctgcccgg caccgacagc accccggtcg
    50881 acctgcggct ggaccggtcc cgcttcgaca tgatggtcag cctcgtcgac cacggcgacc
    50941 ggtactcggt gctcaccgag tactccaccg acctgttcga cgcccggcgg gtacgcgcca
    51001 tgctcgacca cgtcgcccgg ctgctcgacg cgggcctggc cgacccggct acgacgctgt
    51061 cgcggttgcc gatgctcgac cccgccgaac gcgagcgggt cctggccctc ggcgcgggtg
    51121 aacgacgtga cgtggcccct gccaccgtcc accagctggt ccgggcgcag gccgaacgca
    51181 accccgacgc ggtggccgtc cggcacggcg atcacgagct gacctaccgg gagctgctgg
    51241 accgggccgc gcggcgggcg gccggcctgc gcgacgcggg cctgcgaccc ggcgatcggg
    51301 tgccggcgct gctggaccgg ggcgtcgacg aggtgctgac gccgatggcg atctggcacg
    51361 ccggtggggt gtacgtgccg ctggacaccg ccgccccgcc gaaccggctg cgccggatcc
    51421 tgaccaactg tgccgcccgg ctcgtgctca cccgcaccga gcacgccgcc ggggtgccgg
    51481 agggcccgtg gcggaccctc ctgctcgaca ccggcgacct ggactccgcc gccgggctcg
    51541 ccccggaacc gtccaccggc ccggacgacc tggcgtacgt gctgcacacc tcgggcacga
    51601 cgggtgaccc gaagggtgtc cagctgccgc accggggttt cgtcacctac ctggactgga
    51661 tgcgcgacca gtggcgctgc gggcccggtg accgggtgtt gcacggctgc gcgccggtgt
    51721 tcgacctggc ggcgggtgag gtgctggcgg cgctcacctc cggcgccacg gtggtggtga
    51781 tcggcaagga ccggctgctc tcgccgggcg gtctcgccga ggtcctggcg gccgaacgga
    51841 tcacgcacct gttcctgacc ccgaccacgc tcggtctggt cgaggacgac accgaccggt
    51901 tcgacgcgtt gcgggaggtg ctggtcggtg gcgaggtctg ccccgccgac ctggtggccc
    51961 ggtgggcgcg cccggggcgg cgtcggttcg tcaacctgta cggcccgacc gaggccaccg
    52021 tgggctgcct cgcccacgac tgcacggact ggtcggcggc caccccaccg ccgatcggcg
    52081 cgacgatgcc gaaccgccgc acctacctgg tcgaccgctg ggacaacccg gtcccggtcg
    52141 gggtgccggg ggagatcctg gtcggtggcg cggcgctgag caccggctac ctcaacgacg
    52201 acgagctgac cggacgccgg ttcaccgcgg atccgttcga tccgcaggga cgggtctacc
    52261 gcaccggcga tcgtggtcac tgggacgcgc agggccggct gcacttcggc ggccggctgg
    52321 acggccaggt caagttgcgc ggcctacgcg tcgaactcga cgagatcgag gcactgctga
    52381 gccggcactc cggggtggcc cgcgccgccg tgaccgtggt ccgcgacggc aacggggtgc
    52441 agcggctcgt cgggtacgtg gtggacgccg ccgagccggc cagcgacgcg gacctgcgca
    52501 cgcacctgag cacggagctg cccgcccacc tggtgcccgg ccggttcgtc cgactgcccg
    52561 ccctgccgtt gaccaccagc ggcaaggtca accggcgggc gctgccggca ccggaggcgg
    52621 cggacaccga cgacaccggc gcggccccca ccaccggggc cgagcgccag gtcgcggaga
    52681 tcttcgcgga ggtgctgggg gtggcgcggg tgggcgcgga gacgtccttc ttcgacctcg
    52741 gcgggcactc gttgcaggcg gcgcacgtgc tggcccgcat cgccggacgg atcggcacgt
    52801 cggtgtcgct caagcagttc tacgccaccc cgaccgtccg ggcggtggcc cggttcgtcg
    52861 agcacgggcc ggtggtggac gcctcgccac tcgtcacgct caaggccacc ggttcgcggc
    52921 cccggctcta ctgcccgcac gcggtctccg gctcgccgta ctggtacctc ccgctgagcc
    52981 gggccctgca tccggagcag ccggtggacg gcttcgaggc gccggggctg gagggtggca
    53041 tcgagccggt cgacgacctg gtgacgctcg ccgggcggta cgtcggcgcg ctgcgcgaac
    53101 ggcagccgca cgggccgtac ctgctcgccg gctggtcgat ggggggcttc ctctgcttcg
    53161 agatggcccg acagctcgcc gccgtgggtg ccgcaccgga cctcgtggtg atgatcgact
    53221 ccaatgaacc cggcccgttg ccgctgccga gcgagcgaca ggtgatggag accttcgtcg
    53281 ccgacctggc cgggctctcc gcggcaccgg caccgccgct ggacgccgag gtggtcgacg
    53341 cggccgaccc gatcgcggcg ctcaccgggt tcctggtccg gcacggactg atcccgtcgg
    53401 acgtgcgggc cgacttcgtc gccaaccggt acgcggtgtt ccgcgccaac atgcgggcca
    53461 tctacggcta ccaaccggca ccgtacgccg gccggacggt gctggtgcag gcggagcggg
    53521 aggccagccg cgcggcgtgg cgccggtgga gtccggcgat ggaggtggtg acgctgccgg
    53581 gcgaccacta ctcgatgtgg tccccgcagc acctgcccgc gctggcagcc ctcatcgacg
    53641 accaggtggc acgggtgctc gacctcggct gaccggcacc ggggcccgcc cagaccatcg
    53701 gctgggcggg ccccggacga gcatcgtcac cggcggcgag cctggtcacc tcggcgcgga
    53761 acgcgctccg gtcggcgcgg acgactcctc gaccgggccc gttgccggct cgacgtcgac
    53821 ctcaccgggg ggtgcgttgc ccggcgccgc cacggcctcg acctgctcgg cggcgtcgcc
    53881 gctcggcgcc gtctcagccg acacccgggt ggacagccgc caggtccggt aggccagcag
    53941 gaatcccagc atcagcagac cggcgtcgac ccagaggctg cggctcaacc ccagcgcgga
    54001 acggctcggg tcgttctcgg cggtcgccag gtagacgccg ccgacgacga ccacgctcac
    54061 cacgctggcc agcagcgttc cggtcgagac cagggccgac agggcggcgg cgtagcgggg
    54121 gcccacggtc gcggccgtct gctccacgag cgtgctgaaa ccggccgcca tccccgcacc
    54181 ggcgagcagc agcagcgccg acaccaccgc gatcggccag ccgccggcca ccacgaccgc
    54241 gagtgcggcc agggccaggg cgaacaccag caggccggcg accggcagcg ggcggtggaa
    54301 acgtttcggc agccgtgtcc aggtgaggct gacggccgcg aaacccacgg ggtacgggat
    54361 gaacatcaac ccggcctgca acggtgtgta gcccagcccg ttctgcacgt gcagggtgag
    54421 cggaaacagc accccggcga aggcgaagtt gaggatgcag caggccagca gtcccgactt
    54481 gacgcctcgc ggtcgcagcg catcgatctc cagcaccggc tgtccgcccc gggcgcccag
    54541 ccgcagctcg taccggacga agaggacgag cccggccgtg ccggcggcga tgctggccag
    54601 tgcccacgcg ggccagccct gttcccgccc gaagaccagc ggtgccacca ccgcgcccat
    54661 cgagacggcg agcagcagga tgccgacgat gtcgggccgg aaccgcgagc tgggcgtgtg
    54721 ccccggcaga taacgcggcg ccgccgccag cagggccagc ccgatcggca cgttgaccag
    54781 gaacgcggcc ctccagccgc tgcccagcac gtcggcgctg acgatcacgc cgccggcgat
    54841 ctgaccggcg gccactccga gcgccagcac catcgagtag agcccgatgg cgcgggcccg
    54901 ggccgacccg gtgaagacga tctggatcac cgagagcacc tgcggcacca tcatggcccc
    54961 gaacgccccc tgcagcaggc gggcggcgac cagcgtgccc gcggtcgggg cgatcccgca
    55021 gagcagcgag ctggcggtga agccggtcag cccgatcatg aacagccgcc ggtgccccac
    55081 gtcgccgccg agtcgcgcgc cggtgaccac gagcaccgcg aacatgagcg tgtatccgga
    55141 caggatcagt tgcagaacgg cgccggaggt ctggaggtca tccttgatgg tcttggtggc
    55201 cacggcgacg atggagttgt ccatcgtcgc catgacctgt gccaccagga ggatgagcag
    55261 caccagccgg gcgccccgtg gtcgaccttc gtcctcagtg gccatcgaca ctcctcgctc
    55321 tttctggttg tcacgcccgt tgccgtggta gaggcttccg tgccgacagt ggttgcgcaa
    55381 ctacgtgcgg ctgggtgtcg cgggcgtgcg ggcatcccgc ggatcgtcgt cgtcggagac
    55441 cgccggtcgg gtcgccggca caacgttgcc ggtcgccgac cacgccaccg acgccgggct
    55501 ttcggtgtcg gtggggccgg tgcctggcgc gggaccggtc cgggacaccg gcacagtgcc
    55561 gacgccgcga cgcgcgagcg gcccgaccga ggcacccaac tccggcccga acaccagcag
    55621 caggacggtg gcggccaggc acagcacacc cagtgcgatg gccggcgcga cgagcccgcc
    55681 gccgagggag agaatcagca gcatggcgga cggtccgagg atgccaccga ccttcgtggc
    55741 cgccccggcg aagccggagc cggtggcccg catcgcggtc gggtagatct cggcgctgta
    55801 cggcagcagc atcgcgttga ccgcggacaa cgacagcacc agcaggccga tggaggccag
    55861 cagcagcacc gtcccgccgc tgtcggtggt ccagagggcc actccgccga gcccgaccgc
    55921 ggttatcgcg atgaacagcg ccagcgcgcg gcggccgctc caggccgcgt agagcagcac
    55981 gaccagcgcg agggccgggg tggagtagag cgccgagtcg gccagcagcc cgctcgcgac
    56041 accgccggcc aggcccgcct cgcgcagctg cgcgggcagc atcaccagga agccgaagtt
    56101 caccaggccc cagacgacac cgaccacgcc gatcaccgat gtcacgaccg gatacgcccg
    56161 cagcatcgcc cccacgccgg gacgcgtcgc ggcggcggca gtgtcggcgg ccgggggcgt
    56221 ggcacccagg tgggacccgt agcggcggag caccgcctcc gcctcggtac gccgcccggc
    56281 gcgcagcagg tacagcggcg actcggggat caacggcgcc atcagcagca gcagcagtcc
    56341 ggagggcagc ccgatcaacc agagtgcgcg ccaggtcagc gccggctcca ggtggcgtgc
    56401 cgcctcgctg gccgccaggt aaccgccgag gccaccgatc ccaccgacgg tcaccgccac
    56461 ccagccgcgg tgccggcgtg gggtcagctc ggcgatcagc gtgaacacca ggggcaacag
    56521 gccaccggcg gaggtgccca tcgtgaagca catgacgagg ttccactcga aggtgggcat
    56581 ggccccgcac gccgaggtcg cgatgaacag cagggtggcc aggagcaggg cggtccgtcg
    56641 accgtaccgg tcgccgagca ggccccagac gaccgacccg accgcggtgc cggtgagggc
    56701 caccaggggc aggatcgaga ccgattcgag ggacatgccg tactcgtcgc tcatgccggg
    56761 catgacgaag ccgagggtca gcggcttcat gatgtcgacc accagggcga tggtcagcac
    56821 cgcgcaggtg atccagtacg cgggtcgcag ccgcccgtgc tcgatcgact ccacggtgac
    56881 gctcgcggag tccggtcggc ggacccccgc gaacagcgcc cgcccggcca ccaccaggcc
    56941 gacgacgagc agcagcatgc cgaggatcat cgtcggcgtc cacatgtcca tcggctcgcc
    57001 ggggctcatg ccctccatgc ccggcatgct gtccatgtcg tccatgtcgt ccatgccgtc
    57061 catgccgggc tcggccgacc ccatccgggc atggtcgatc atcatcttca cgtcgggcag
    57121 ttggaacagc acgccggccg tcaccaacgc cacgccgagc aggaatccga gtgtcccgcg
    57181 gcgtttcgcg gatgctgtgt cggcagtgcg ggattcggac atggttgacc gacctccgag
    57241 ctgtcgcgag acgagaagaa cgtcggcgaa ttggcgacca ccgaaatcta caagggtgct
    57301 tcccgggtga caaccgtcaa ttatatgact catttcggta agtggttatg aattgctgcc
    57361 tccgggtggc tcaccctgtt tgctaccgat ttggtgggct ctgatcggtc agtcagtcga
    57421 cgagcgttgc ccgatcgccc cgtgggatgt taggctcacc ctaagtgatc aactggcggt
    57481 cgccggtgct gtccaatggt ccgcttacca cagcttttcg gcaggtcagt gccgttatgg
    57541 cggatcgttg gtcgcgggtg acgcgcaccg cgtcgtcgga tccgccgggc ggtggcgctg
    57601 tccgcgccag gccggcacgg cgcagcggct gacccgactt cagcaattaa ccgagcgtat
    57661 tcttcagtga attgctggca atctctccgt aacgctccgg gccgcacgga aatgctaggg
    57721 tcgggagcga tgcccgccgc ccatcgcctt tcgactgagg tcgacggcgg gctggatcgg
    57781 gcgtgagctg cgccgtttct cgaatcgcta tccgaccatc cgtacgcgac cgcgaccccg
    57841 gcacgcgccg accggcccgg atcgatcccc tcggtcactg tcggtgccgc agatgtgccc
    57901 catgtggacc ggtcggcccg atccggcccg tgttgtgcca gcatggacta catgaccatc
    57961 cagtccgacc cgatggcgtc gacggacgag gtacgcggtg agccggccga cgagttcgtc
    58021 ggcgccctcg tctcgctgag ccgggtcatg gtggccgtcg ccatgcggac gctggcgcgc
    58081 atcgacgccg acgtgacgct ccagcagttc cggacgctcg tggtgctggt gcccggcccg
    58141 cagcgggtga tcgacctggc gaagctgctc ggcgtgcagt cgtcgaccgc cacccggatg
    58201 tgcgaccgac tggtccgcaa ggggctggtg gcacggcacg agcgggtggc ggaccgtcgg
    58261 gctgcctggg tcgggctgac cgtcgccggc aaggaactcg tcggcctggg catgcgagcc
    58321 cgacaacagg aactggagcg gatgctggcc gacctgcgac ccgacgacac cgacgtcacc
    58381 accggcgcgc tggtggcggt actgcgcgcc accggtgagc tcaccgacgg tgcctggtgg
    58441 cggcagtggg cggattcggt ggtggagtga cgcaacgccg tcggtcccga gtggccggcg
    58501 cagccggggc cggccgtcgg cgcggctggg gtcagacggt gacgcggctg gccgcacggc
    58561 ggcgggccat gggcatcgac ggcacctcgg cggccggacg cggtaggtcg gacggtgtca
    58621 cgtcgaccgg cgacacgccg gccgagacgg cgtcctgcga cgccgcgttc cggagttgat
    58681 cgagggcggc gtcgaggctg tcgaagatcg ggaaaacccc gtcgagcttc atcgtgtgca
    58741 gcacggtgcg gatgaacctc gacggcgcgg cgaggcacag ccgcccgcca cgctcgcgta
    58801 cgtcgcgatg cgcccggacg agcatgccca gcccgagcga gtcgatgacc tgcacctggg
    58861 tcaggtccac caccaccgtc ccggccacgt cgaacgcgcc gcgcagcgcg gcccgcagcg
    58921 cgtcgccggt gtcctggtct ccgccgtcgg cgggcaccac caccgccgcc tcggcgaggc
    58981 ccgatccagc ccggtcgccg tcaccgaggg agctgcccgg cggcagcgcg ctgcaccggg
    59041 ggcagcggtg cgggccggtg gcgaacggcg acccgctcca cccgtggtcg gagaccagcg
    59101 tccagacgac ctcggcgtcg ggcagcacgc aggcggtgcc ggtggtggtg tcaccacaga
    59161 cgtcgcagat cagggtcatc aggttgtcgt ccggtacgac ggtcatcctg cttcctctcc
    59221 ggtgccgcgg ccggtcggcc gcggtgcggg actcggggcg ggggcgggtg aggcaccctc
    59281 gccgtacgga ctcctcacag ggagtcggag cgttccttgc cggtggtggc gaccacgatc
    59341 accaccgcga ccgcggcgag cccggcctgc acgaccaggc ccaggatgct gaacccctga
    59401 acgccggcga gccaggcggt gatggcaccg agcaacgagg cgacggcacc gatggtcatg
    59461 gtgagccaca gcggcgcagc cggacggccg ggcaggacca gtcggccgag cgcgccgacg
    59521 gcgaggccga cggcgagggc cgtgacgatc ccggcgctgg tcatgctgct cctcgtgctc
    59581 gcggtcagat gcgtcggctg cggtgtgtca ggtgcgcacg gtgacggcgg cgcggccgta
    59641 cgcggcagcg cgcgggaccg tacccggtgc cggtgtcccg tcggccggcg ggacacccgg
    59701 tgcggcggtg accgcctcgg tgaccggggc cgaggcggcg tcggtgtgca ccggcaggat
    59761 ctggtccagc cgggcggtct gcaggatgcg ggtgatgcgc gggttcgggt tgcggacggc
    59821 cagcacgccc ccggcacgga ccatccggcg gtgcacgtcg agcagtagac cgatggcggc
    59881 ggcgtcgatg tgccggcaac ccgccaggtc gatcacgacc tgaccgggac gcagggccag
    59941 gagctgatcg aggaccgcgc cggtctccgg caggcagctc agatcgaact cggtgatgga
    60001 cacctccacc agcggcaccg aacactcggg gcgtcgtggt gcggtcacgg ccaaggcccc
    60061 ctctcctgcg gtctccgagt ggctctcacc ctgcccagcg gggttggcgg ccaccgcgcg
    60121 gacggatgac agttgcgtga caaaaccccc ggttgtcgat cgtggttggc ccggcggtca
    60181 gggcttgggg atgattccgg tatgacagcg gtactggtga tcgaggacga cgaccggatc
    60241 cggttggcgt tgctgctcgc tctggaggac gagggctacg aggcccgggg agcggccacc
    60301 gccgaggagg ggctgcgtac gcaacgccgg gatcccgccg actacgtcct ggtcgacctg
    60361 atgctgcccg gcatcgacgg cttcgagggc atccgccagt tgcgccgcga cgacgacgtg
    60421 ccgatcgtcg tggtcagcgc ccgcgacgac actcacgaca tcgtcgccgc cctcgaggcc
    60481 ggcgccgacg actacgtggt caagccggtg gcgatcaagg aactgaccgc tcggctgcgc
    60541 gccctgcgcc gacgcgggcg caccacgacc gcgtcggacg gcccgcagcc ggtgccggtg
    60601 ctcgccttcg gtgaccttga ggtgagcccc gaggcggggg aggtgcgccg cgccggtgag
    60661 ccggtcgcgg tcacccgcac cgagttccgg ctgctgtgcg agctggccga acacgccggc
    60721 cgggtgctct cccggcagca gctgctcagc cgggtctggg ggtacgacag cggcgacgaa
    60781 cggcttgtcg acgtgcacgt cggtcggctg cgccagaaga tcgaagccga tccggccaac
    60841 ccccgacatt tggtgacgct gcgcgggctg ggttacaaac tgcaacgatg agacgcctcg
    60901 gactgcgtgc ccgggtcacc gccgcgttcg cggtcggtgc gttgctgctg tccgcctcga
    60961 tggccctggt gtcgtacgag ctgacccgcc gcaccctgct cgacgagcgg gaacgcaccg
    61021 tgctgcgggc ggcgtactac gacgcggcgg tggtccgcgc cgggctcgac accgacaacc
    61081 cggacgtcgc ggaggcgttg cgggcgttgg acaccggcac cggacggcga cccctggtgc
    61141 tgctcgacgg cgagtggtac gcccgcagcg ccgacaacgg gctcaccacg atcgttccgg
    61201 cccggcttca ggacctggtc gcggcggggg agccggcggt gcagcgggtg cgcgtcaacg
    61261 acaccccggt gatgctggtc ggtgtgccgc tgtccgagtc gaccgccttc tacgagatcg
    61321 cctcgctgcg ggaactggaa cagaccttcc aggtgctggc gctggcgctc accgcggtcg
    61381 cgatcatgat cgccgggtcc ggggcggccc tcggctggta cgccacccgg cacgggctgc
    61441 gtccgctgac cgccgtcgcc gacgccgccg agcggatcgc ggccggcgac ttcaccaccc
    61501 gcctcgcccc cgacaccgac ccggacctga cccgtctgtc cacctccttc aaccggatgg
    61561 tcgacgagtt ggccgggcgg atcgaccggg accggcgttt cgccgccgac gtcagtcacg
    61621 aactgcggtc gccgttgcag accctcgccg ccgccgcgag tgtgctgtcc cggcgccggg
    61681 agaaccagga cgagcggacc gccaccgcgg cccggctcgt cgccgacgag atcgaccgtt
    61741 tccagcaact ggtgaacgac ctgctggacc tggcccgtgg tgaccagccg gtgcaccggg
    61801 agtcggtgga cctgcccgag ctggcccggc aggcgtgccg ggaccgggac ctgccggagt
    61861 cgatggtgca gttggcaacg gggacaccgc ccgggtggcg ggtggaccgt cgccgggtcg
    61921 cccaggtgtt ggccaacctg ctggacaacg ccgagcggta cggtgcggga ccggtcgcgg
    61981 tgcggctgtc ccacgacgcg gacacgggcg tgatcgaggt cgacgacgag ggcccgggag
    62041 tgccgatgga ggaccgcgag gcgatcttcg accgtttcgt ccgggggcgg gcggccaact
    62101 accgtggtgg cggcgacggc accggcctgg gcctggccct ggtggcccag cacgccgccg
    62161 cgcacggcgg agacgcgtcg gtcagcgacc gcccggaggg cggtgcccgg ttccgggtca
    62221 ccctgccggg gagcctgtca tgacccgccc cggcaccggc cgggccgcgc ggacggtcgg
    62281 ggtcgcggcg ctcgtcaccg tgttcgccct gctcggcgcg tgcggggtgc ccgccgagga
    62341 tcgaccccgc gcggtgacgc cgccgccggt gccgttcccg gcgaccgcct cggccgcgcc
    62401 gacggcggcg gagaccggcg cggtgaccga ggtgctctac ttcgcccgcg acgaacgcct
    62461 ggtgccggtg atccgccggg ccgaccaggt gcccgcactc gacgcgcagc tgcgggcgct
    62521 gctcgccggg ccgaccccga ccgagcgtga cgacgggctg accagtgccc tgccgggagc
    62581 cttcaccagc gcggtggtcg agctggtcga cgggttggcc cgggtcaccg tcgggctgac
    62641 ggcggtggac accggccgca gcgacggccg gctggcgtac ggtcagatcg tctgcacgct
    62701 caccgcccgc accgatgtca cggcggtgct gttcctggaa ggcggcacgc cgctgagcgt
    62761 cccccgggcg gacggctcgc tgtcgtcggg accgctcacc gctgccgact acgccgtgtt
    62821 gatcaatcct cgttgacgag ggccggacca cccgacgcac gcgcagcgcg acgactcgta
    62881 tcctttccgc gaaccgtcgt gccgacgacc ggaaaggact tggtgtgaac gaccgggccg
    62941 agacgttgga gttccaggcc gaagcgcgtc agctgctccg gctgatggtc cactcgatct
    63001 actcgaacaa ggacgtcttc ctccgcgagt tgatctcgaa cgcctcagac gcgctggaca
    63061 agctgcgcct ggcgtcgatg gtcgacaagg acctcgccgt cgacaccggc gacctgcaca
    63121 tcgccatcga ggtcgaccgg gacgcccgca ccctcaccgt gcgggacaac ggcatcggca
    63181 tgagccgcga cgaggtggtc tccgtcatcg gcaccatcgc caagtccggc accgcggagc
    63241 tgctgcggca gctgcgggag gccaaggacg ccggcgcctc acaggagctg atcggtcagt
    63301 tcggcgtcgg cttctacgcc gcgttcatgg tcgccgagcg ggtcgagctg gtcacccgac
    63361 gggccggcga gaccggtggt acccgctggg agtccaccgg cgagggcacc tacaccatca
    63421 ccgagctgga cgacgccccc cagggcacgg cggtgaccct gcacctcaag cccgccgacg
    63481 ccgaggacaa cctgcacgac tacaccgccg aatggacgat ccgggggatc gtcaagcggt
    63541 actccgactt catcgcccac ccgatccgga tgaccgtcga gcggcccggc accgacgacg
    63601 cccccgccac caccgaggcg gtgacgctca actcgatgaa ggcgctgtgg gcccgcccgc
    63661 gcggtgaggt cgagcccgcc gagtaccacg agttctacaa gcacgtcagc cacgactggg
    63721 cggacccgct ggagaccatc cacatgcggg gggaggggac cttcgagtac gaggcgctgc
    63781 tgttcatccc cacccacgcg ccgctggacc tgttctcccc ccagggccgc cgaggggtgc
    63841 agctctacgt caagcgcgtg ttcatcatgg acgactgcga cgcgctgatg cccaactacc
    63901 tgcggttcgt caagggtgtg gtggacgccc acgacctgtc gctgaacatc tcccgggaga
    63961 tcctccagca ggaccgccag atccgcgccg tccgccgtcg cctggtcaag aagatcctcg
    64021 ccacggtcaa ggatctcaag accggccagc cggagcgcta ccgcaccttc tggaccgagt
    64081 tcgggacggt ggtcaaggaa ggtctgctgg aggacaccga caaccgggac accctgctgg
    64141 agatcctctc ggtggcctcc accaacgacc cggccgagca gaccgacctg gccggctacg
    64201 tggaacgcat gcgcgagggc cagcaggaca tctactacgc caccggcgag aaccggagca
    64261 ccatcgagaa ctccccgcac attgaggcgt tccgcgccaa gggctacgag gtgctgctgc
    64321 taaccgaccc ggtcgacgag gtttgggtgg agcgggtcgg cagctacgcg ggcaagacgc
    64381 tgcgctcggt cgccaagggg caggtcgacc tggacaccga gcaggagcgc accgaggccg
    64441 aagccgaacg ggagcggcag cgcaccgagt acgccgacct gctcggctgg atgggcgagg
    64501 tgttggccga caacgtcaag gaggtccggc tgtcgtcgcg gctgaccacc tcgccggcct
    64561 gcgtggtcgg cgacgcgcac gacctcacgc ccaccctgga gaagatgtac cgcgcgatgg
    64621 ggcaggaggt gccgaaggtc aagcggatcc
//
