BGC0000448: tomaymycin biosynthetic gene cluster from Streptomyces achromogenes
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Location: 1 - 25,954 nt. (total: 25,954 nt).
This entry is originally from NCBI GenBank FJ768957.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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General
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0000448
Short description tomaymycin biosynthetic gene cluster from Streptomyces achromogenes
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: FJ768957.1
Compounds
  • tomaymycin
Species Streptomyces achromogenes [taxonomy]
References
Chemical products information
tomaymycin
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C16H20N2O4
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACN39014.1
  • tomA
 1 - 1905 (+) putative nonribosomal peptide synthetase TomA
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  • ACN39015.1
  • tomB
 1985 - 6613 (+) putative nonribosomal peptide synthetase TomB
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  • ACN39016.1
  • tomC
 6695 - 7915 (+) putative 3-deoxy-D-arabinose-heptulosonic-7-phosphate synthase
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  • ACN39017.1
  • tomD
 7912 - 9945 (+) putative phenazine biosynthesis protein PhzE
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  • ACN39018.1
  • tomE
 9938 - 10558 (+) putative phenol-2-monoxygenase reductase component
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  • ACN39019.1
  • tomF
 10564 - 12165 (+) putative phenol-2-monoxygenase oxygenase component
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  • ACN39020.1
  • tomG
 12252 - 12956 (-) putative O-methyltransferase
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  • ACN39021.1
  • tomH
 13271 - 13708 (+) putative L-DOPA-2,3-dioxygenase
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  • ACN39022.1
  • tomI
 13705 - 14661 (+) putative tyrosine hydroxylase
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  • ACN39023.1
  • tomJ
 14748 - 15707 (+) putative F-420 dependent reductase
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  • ACN39024.1
  • tomK
 15704 - 16567 (+) TomK
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  • ACN39025.1
  • tomL
 16621 - 18354 (+) putative gamma-glutamyltransferase
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  • ACN39026.1
  • tomM
 18439 - 20790 (+) putative UvrA-drug resistance pump
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  • ACN39027.1
  • tomN
 20912 - 21112 (+) putative tautomerase
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  • ACN39028.1
  • tomO
 21181 - 22365 (-) putative NADH-dependent flavin oxidoreductase
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  • ACN39029.1
  • tomP
 22536 - 24449 (+) putative anthranilate synthase
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  • ACN39030.1
  • tomQ
 24506 - 25954 (-) putative flavin-containing amine oxidase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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