BGC0000448: tomaymycin biosynthetic gene cluster from Streptomyces achromogenes
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Location: 1 - 25,954 nt. (total: 25,954 nt).
This entry is originally from NCBI GenBank FJ768957.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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General
Compounds
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Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0000448
Short description tomaymycin biosynthetic gene cluster from Streptomyces achromogenes
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
FJ768957.1
via
Compounds
  • tomaymycin
Species Streptomyces achromogenes [taxonomy]
References
Chemical products information
tomaymycin Evidence:
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C16H20N2O4
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACN39014.1
  • tomA
 1 - 1905 (+) putative nonribosomal peptide synthetase TomA
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    • ACN39015.1
    • tomB
    		 1985 - 6613 (+) putative nonribosomal peptide synthetase TomB
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      • ACN39016.1
      • tomC
      		 6695 - 7915 (+) putative 3-deoxy-D-arabinose-heptulosonic-7-phosphate synthase
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        • ACN39017.1
        • tomD
        		 7912 - 9945 (+) putative phenazine biosynthesis protein PhzE
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          • ACN39018.1
          • tomE
          		 9938 - 10558 (+) putative phenol-2-monoxygenase reductase component
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            • ACN39019.1
            • tomF
            		 10564 - 12165 (+) putative phenol-2-monoxygenase oxygenase component
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              • ACN39020.1
              • tomG
              		 12252 - 12956 (-) putative O-methyltransferase
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                • ACN39021.1
                • tomH
                		 13271 - 13708 (+) putative L-DOPA-2,3-dioxygenase
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                  • ACN39022.1
                  • tomI
                  		 13705 - 14661 (+) putative tyrosine hydroxylase
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                    • ACN39023.1
                    • tomJ
                    		 14748 - 15707 (+) putative F-420 dependent reductase
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                      • ACN39024.1
                      • tomK
                      		 15704 - 16567 (+) TomK
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                        • ACN39025.1
                        • tomL
                        		 16621 - 18354 (+) putative gamma-glutamyltransferase
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                          • ACN39026.1
                          • tomM
                          		 18439 - 20790 (+) putative UvrA-drug resistance pump
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                            • ACN39027.1
                            • tomN
                            		 20912 - 21112 (+) putative tautomerase
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                              • ACN39028.1
                              • tomO
                              		 21181 - 22365 (-) putative NADH-dependent flavin oxidoreductase
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                                • ACN39029.1
                                • tomP
                                		 22536 - 24449 (+) putative anthranilate synthase
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                                  • ACN39030.1
                                  • tomQ
                                  		 24506 - 25954 (-) putative flavin-containing amine oxidase
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                                    Biosynthesis information

                                    No biosynthesis information available for this record.

                                    Annotation changelog

                                    Entry version: 4

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2022-10-07
                                    Update chemical activity to schema version 2.11
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 3

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2022-09-15
                                    Updated bioactivity data
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 2

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2019-10-16
                                    Migrated from v1.4
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    2019-10-16
                                    Updated compound(s) information (NPAtlas curation)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 1

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2015-06-12
                                    Submitted
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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