BGC0000460: vulnibactin biosynthetic gene cluster from Vibrio vulnificus CMCP6
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Location: 890,623 - 914,333 nt. (total: 23,711 nt).
This entry is originally from NCBI GenBank AE016796.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000460
Short description vulnibactin biosynthetic gene cluster from Vibrio vulnificus CMCP6
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: AE016796.2
Compounds
  • vulnibactin
Species Vibrio vulnificus CMCP6 [taxonomy]
References
Chemical products information
vulnibactin
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C35H39N5O9
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • VV2_0828
  • AAO07752.1
 890623 - 890961 (+) hypothetical protein
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  • VV2_0829
  • AAO07753.1
 891012 - 891707 (-) Phosphopantetheinyl transferase component of siderophore synthetase
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  • VV2_0830
  • AAO07754.1
 891712 - 894780 (-) Non-ribosomal peptide synthetase module, siderophore biosynthesis vulnibactin-specific
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  • VV2_0831
  • AAO07755.1
 894850 - 899412 (-) Non-ribosomal peptide synthetase module, siderophore biosynthesis vulnibactin-specific
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  • VV2_0833
  • AAO07756.1
 899638 - 900708 (+) 3-deoxy-7-phosphoheptulonate synthase
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  • VV2_0834
  • AAO07757.1
 900940 - 901728 (-) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
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  • VV2_0835
  • AAO07758.1
 902100 - 903281 (+) Isochorismate synthase
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  • VV2_0836
  • AAO07759.1
 903291 - 904928 (+) 2,3-dihydroxybenzoate-AMP ligase
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  • VV2_0837
  • AAO07760.1
 905047 - 905862 (-) Vulnibactin utilization protein VuuB
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  • VV2_0838
  • AAO07761.1
 905926 - 906813 (-) Isochorismatase
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  • VV2_0839
  • AAO07762.1
 906916 - 907245 (-) Isochorismate pyruvate-lyase of siderophore biosynthesis Vulnibactin-specific
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  • VV2_0840
  • AAO07763.1
 907474 - 909102 (-) 2,3-dihydroxybenzoate-AMP ligase
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  • VV2_0841
  • AAO07764.1
 909328 - 909570 (+) Aryl carrier domain protein
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  • VV2_0842
  • AAO07765.2
 909626 - 910534 (+) ABC-type enterochelin transport system, periplasmic component
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  • VV2_0843
  • AAO07766.1
 910619 - 912676 (-) Ferric vulnibactin receptor VuuA
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  • VV2_0844
  • AAO07767.2
 913017 - 914333 (-) Amide synthase component of siderophore synthetase Vulnibactin-specific
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
VV2_0836
Module ?
Specificity: salicylic acid / 2,3-dihydroxybenzoic acid
Evidence for specificity:
  • Structure-based inference
  • ATP-PPi exchange assay
  • Sequence-based prediction
VV2_0840
Module ?
Specificity: 2,3-dihydroxybenzoic acid / salicylic acid
Evidence for specificity:
  • Structure-based inference
  • ATP-PPi exchange assay
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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