LOCUS       BGC0000460             23711 bp    DNA     linear   BCT 30-JAN-2014
DEFINITION  Vibrio vulnificus CMCP6 chromosome II, complete sequence.
ACCESSION   BGC0000460
VERSION     BGC0000460
KEYWORDS    .
SOURCE      Vibrio vulnificus CMCP6
  ORGANISM  Vibrio vulnificus CMCP6
            Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales;
            Vibrionaceae; Vibrio.
COMMENT     On Jan 25, 2011 this sequence version replaced AE016796.1.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:41:09
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 23711
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23711
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[4227:23711]"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4228..23711
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="1"
     protocluster    1..23711
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[4227:8790]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      4228..8790
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
     cand_cluster    1..23711
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="NRP-metallophore"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..23711
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000460"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..23711
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="NRP-metallophore"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="(VibH_like or Cy_tandem or (cds(Condensation and
                     AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or
                     TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or
                     (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or
                     PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like))
                     or Lys_monoox or VbsL)))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..339
                     /locus_tag="VV2_0828"
     CDS             1..339
                     /codon_start=1
                     /locus_tag="VV2_0828"
                     /note="COG3171"
                     /product="hypothetical protein"
                     /protein_id="AAO07752.1"
                     /transl_table=11
                     /translation="MKLDKVENKNRRLRKKLFLGEFAILGFEISCETDIHDFDRYDVFV
                     DDFIDFIDAKGLCFGGGGLEHFEGFICAKERYESATEEQRAAVVEWLNARAEVKSVLVS
                     DLADANYL"
     gene            complement(390..1085)
                     /locus_tag="VV2_0829"
     CDS             complement(390..1085)
                     /EC_number="2.7.8.-"
                     /NRPS_PKS="Domain: ACPS (112-175). E-value: 3e-07. Score:
                     22.1. Matches aSDomain: nrpspksdomains_VV2_0829_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060:4'-phosphopantetheinyl transferase (Score: 202.1;
                     E-value: 1.2e-61)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="VV2_0829"
                     /note="COG2977"
                     /product="Phosphopantetheinyl transferase component of
                     siderophore synthetase"
                     /protein_id="AAO07753.1"
                     /transl_table=11
                     /translation="MRLSDPTTLSLGGHTVWQRQFDASSFEPNSAQAWQIAVPDSLQQA
                     SCKRRAEFVAGRVVARDALVALKSPSYHVCVGEHRAPQWPSGWLGSISHTDHTAICVVS
                     KMHEHAKLGVDMEKFVSERAAKEIMPLILVTPQERALVAATDWPIHRLVSLVFSAKESL
                     FKAIYPTVGRYLEFSHSYVEEVDLHRGKLALCLCRGAEQNMLQQRFTAFFHLHDDSVVT
                     LVSENDQTL"
     aSDomain        complement(561..749)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VV2_0829_ACPS.1"
                     /evalue="3.00E-07"
                     /label="VV2_0829_ACPS.1"
                     /locus_tag="VV2_0829"
                     /protein_end="175"
                     /protein_start="112"
                     /score="22.1"
                     /tool="antismash"
                     /translation="GVDMEKFVSERAAKEIMPLILVTPQERALVAATDWPIHRLVSLVF
                     SAKESLFKAIYPTVGRYL"
     gene            complement(1090..4158)
                     /locus_tag="VV2_0830"
     CDS             complement(1090..4158)
                     /NRPS_PKS="Domain: Condensation_LCL (26-175). E-value:
                     3.1e-10. Score: 31.4. Matches aSDomain:
                     nrpspksdomains_VV2_0830_Condensation_LCL.1"
                     /NRPS_PKS="Domain: PCP (456-523). E-value: 2.6e-15. Score:
                     48.3. Matches aSDomain: nrpspksdomains_VV2_0830_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (556-850). E-value:
                     7.8e-57. Score: 184.4. Matches aSDomain:
                     nrpspksdomains_VV2_0830_Condensation_LCL.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     190.1; E-value: 1.3e-57)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="VV2_0830"
                     /note="COG1020"
                     /product="Non-ribosomal peptide synthetase module,
                     siderophore biosynthesis vulnibactin-specific"
                     /protein_id="AAO07754.1"
                     /sec_met_domain="PP-binding (E-value: 2.5e-12, bitscore:
                     37.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 9.8e-43, bitscore:
                     136.3, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLNLDVSKLEAHRDGILQQTIEPSLGVSEFEQRVWLYHQQHGDG
                     RNQYASAYHLTGEVNMGKLVAALSQLSQDFPIFNQRYLFNDALGLTKQGVDASLLRVDI
                     EQVVSLEQAMQYLMALQNQPIALDDDAPIRFVLYSGDIDGVVLGVVTHQILSERMDWQS
                     VFQRLSVRYNQPSLKRDWEGASPGQSAHIGYTPLTPQSDIGNTCFAWLQSAQPELVVEQ
                     SWPATPKDSPEHPMLARKYRVSLQGSVLDDYGLSQPNKKEVLSVIAALFARYLAVNANT
                     DQCDLYLPYDVERRAFELNGAMIETGLIAIKVPHVSAPIERNSAEILAQLNQSREHYAA
                     SYHGQQEAALVTWLVDPSVHLQLDQVNAEKSLFAAAHPKFAVTLGVGLNCQGALVLELT
                     LAAGASPYIGAFMLEQFVAQIGGKAASSLHLHESDNREPANVSDTTSQTHEQTQAAVEA
                     AILAEFRTALANQTMTADDDFFDFGGHSLIATRVIGRLLSDHGIEIHINDMFSFPSAKQ
                     LARQAKVQQAKVQQAVVHQPSHCEAKATAQSQHNPIALDRAPLSLAQHSLWKAMSKYAS
                     VGLNNIFNLPFALKFLDRVDEAAFGRAFHEILLRHTGLRTRFSTEDNQPYQQVIPVEKL
                     TEYQWFWTSQQNGGLSVSDLLAQEAEYAFDLDNELPLRLRFVTDDADGAQYLSLLFHHI
                     VLDEWSLNTMMDELALAYRCYVQGHEPLWHMQPRPFHEFARKQRASDVNQAHLSYWLNK
                     FEGLPWAEPIFPAHHPLSVEQQVECGEGGWVEIKIPQRVSSQLYALAKARSASLFNVVY
                     AAIAASLRLLGAPEKLIVGTPAAGRLDADYFDTVGYFTTLGVQLVDFAGVKSIWQLIEQ
                     VKNSINESMAYTDIPIDLIEEGLKGVDHDTEGHMFEVFIQLHAKNKFHGAFELSENERV
                     RFQQVDPDKSESGLGLQFEVMEESIDGEQTLRVMMSYMNKNYSPAQVTLLSDVNRRLFE
                     VFAGCVAQDQDLAQLQEQVAALEATACLAHEGA"
     CDS_motif       complement(1609..1677)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0830_0004"
                     /evalue="7.40E-06"
                     /label="C5_LCL_267-296"
                     /locus_tag="VV2_0830"
                     /protein_end="850"
                     /protein_start="827"
                     /score="18.5"
                     /tool="antismash"
                     /translation="LIVGTPAAGRLDADYFDTVGYFT"
     aSDomain        complement(1609..2490)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VV2_0830_Condensation_LCL.2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="7.80E-57"
                     /label="VV2_0830_Condensation_LCL.2"
                     /locus_tag="VV2_0830"
                     /protein_end="850"
                     /protein_start="556"
                     /score="184.4"
                     /tool="antismash"
                     /translation="RAPLSLAQHSLWKAMSKYASVGLNNIFNLPFALKFLDRVDEAAFG
                     RAFHEILLRHTGLRTRFSTEDNQPYQQVIPVEKLTEYQWFWTSQQNGGLSVSDLLAQEA
                     EYAFDLDNELPLRLRFVTDDADGAQYLSLLFHHIVLDEWSLNTMMDELALAYRCYVQGH
                     EPLWHMQPRPFHEFARKQRASDVNQAHLSYWLNKFEGLPWAEPIFPAHHPLSVEQQVEC
                     GEGGWVEIKIPQRVSSQLYALAKARSASLFNVVYAAIAASLRLLGAPEKLIVGTPAAGR
                     LDADYFDTVGYFT"
     CDS_motif       complement(2023..2088)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0830_0003"
                     /evalue="5.50E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="VV2_0830"
                     /protein_end="712"
                     /protein_start="690"
                     /score="28.5"
                     /tool="antismash"
                     /translation="FHHIVLDEWSLNTMMDELALAY"
     CDS_motif       complement(2305..2412)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0830_0002"
                     /evalue="2.00E-09"
                     /label="C2_LCL_024-062"
                     /locus_tag="VV2_0830"
                     /protein_end="618"
                     /protein_start="582"
                     /score="29.8"
                     /tool="antismash"
                     /translation="FNLPFALKFLDRVDEAAFGRAFHEILLRHTGLRTRF"
     aSDomain        complement(2590..2790)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VV2_0830_PCP.1"
                     /evalue="2.60E-15"
                     /label="VV2_0830_PCP.1"
                     /locus_tag="VV2_0830"
                     /protein_end="523"
                     /protein_start="456"
                     /score="48.3"
                     /tool="antismash"
                     /translation="EAAILAEFRTALANQTMTADDDFFDFGGHSLIATRVIGRLLSDHG
                     IEIHINDMFSFPSAKQLARQAK"
     aSModule        complement(2590..4080)
                     /domains="nrpspksdomains_VV2_0830_Condensation_LCL.1"
                     /domains="nrpspksdomains_VV2_0830_PCP.1"
                     /incomplete
                     /locus_tags="VV2_0830"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(3634..4080)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VV2_0830_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.10E-10"
                     /label="VV2_0830_Condensation_LCL.1"
                     /locus_tag="VV2_0830"
                     /protein_end="175"
                     /protein_start="26"
                     /score="31.4"
                     /tool="antismash"
                     /translation="GVSEFEQRVWLYHQQHGDGRNQYASAYHLTGEVNMGKLVAALSQL
                     SQDFPIFNQRYLFNDALGLTKQGVDASLLRVDIEQVVSLEQAMQYLMALQNQPIALDDD
                     APIRFVLYSGDIDGVVLGVVTHQILSERMDWQSVFQRLSVRYNQP"
     CDS_motif       complement(3946..4008)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0830_0001"
                     /evalue="5.50E+00"
                     /label="C2_LCL_024-062"
                     /locus_tag="VV2_0830"
                     /protein_end="71"
                     /protein_start="50"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="SAYHLTGEVNMGKLVAALSQL"
     gene            complement(4228..8790)
                     /locus_tag="VV2_0831"
     CDS             complement(4228..8790)
                     /NRPS_PKS="Domain: Heterocyclization (37-337). E-value:
                     5.9e-95. Score: 309.9. Matches aSDomain:
                     nrpspksdomains_VV2_0831_Heterocyclization.1"
                     /NRPS_PKS="Domain: Heterocyclization (491-757). E-value:
                     6.3e-33. Score: 106.3. Matches aSDomain:
                     nrpspksdomains_VV2_0831_Heterocyclization.2"
                     /NRPS_PKS="Domain: AMP-binding (941-1332). E-value:
                     1.9e-88. Score: 288.7. Matches aSDomain:
                     nrpspksdomains_VV2_0831_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Cy_tandem"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     74.3; E-value: 1.9e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="VV2_0831"
                     /note="COG1020"
                     /product="Non-ribosomal peptide synthetase module,
                     siderophore biosynthesis vulnibactin-specific"
                     /protein_id="AAO07755.1"
                     /sec_met_domain="Condensation (E-value: 9e-38, bitscore:
                     120.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="Cy_tandem (E-value: 2.6e-186, bitscore:
                     609.2, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.3e-97, bitscore:
                     315.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIINVNLGGEMLSNCAPTDDRPTGEVNGLCLDFNMKEMTAMQAA
                     YWLGRQKGNAMEGLAAHLYAEFDGRDLNREALSMAVRALYAKHPMLRLAITAEGQQHIL
                     PLSACHQLTVEDIARYSKPEVEQFLHNKRERMSHQILDLNQSSPIEISVTLLANNEHRL
                     HIDADMIACDAQSFRIVVEELARLYLSAQESDLVMSEEPQITYFHYLDHQQADRYLAQR
                     KASDKQWWQARLSSLPPEPPLPYLSHQDNEARPQTQRLAHQFTHQERVALEALAKEHHL
                     TLTQLFLALFSQVIATGAREHRFRLNVPTFHRGIYDPQIEQAVGDFSNLLIFSAHVDKT
                     QTLLSHCRQVANQLNLLLSHETYSGVQVMRDLSRLAGQVQRSPVVFTSGMDIDGGELFS
                     QQVTDSLGRMNWVISQGAQVTLDAQIAPAYGGILANWDIRSDLLEQEVIESMFAHYVAL
                     IRRLATFPQIMHQTLEQLDAALGQSESKNIAATPLSNLQKSYLLGRSTQIALGGVAMHE
                     FREYRGNLATETVRENLTRLVEQLPALRTHIDQDKLLQFVSPIIELNLKTFDFQHLSRE
                     KALLAVEPLREHYRHKMHDLSGSPWEVCVVQLPPEYASRINTIIFTSFDALIVDGRSHS
                     IILATLLGQQEDGIQDLLPPRSPKRQGPVIDTAKRAQDERYWQEKLHRDCLPPALPWKQ
                     PLETIRTSRYARESLQIRRAELQQLTLLGAENGLFVNSLLTAAIVQVLACWTTENGMRI
                     GFPVVIPQQDELAGNESTFVILEHEKSDASVLSQALDLQSDMLEALEHLDFSGVDVNRL
                     LMNGSSPALALPVVITNGLSWQTLKETDDVALFSGVTQTPQMALDIRLTYDEQKNLIVS
                     FDYAVDALETNVVCDILNALKTLLQQLSESQQGLLPSSSFLDLSHYRLNSDETQRDPSD
                     FLSHIARQLFDEANEKTAIICGENTVSYAELGSKVACVIGQLNVRGLQQGSVVAICLPR
                     SVEHLVMTLACSLSGMVWVPIDASSPHDRLAYLLSNCNAELVVTQHGDVVASVAFSELL
                     SPIASEAPLPSDEQLSCLSQSTQTAYYLYTSGTTGKPKCVVVNNQATSNVIGQTCREWS
                     ISSQDVIMSVTPYHHDMSVFDVFAAFSSGATLVLPGADGEKDALKWNQLIEQHKVTIWV
                     SVPAILEMLLSCTQGSQLQSLRLVAQGGDYIKPATIAQLRALESSIRLISLGGPTETTI
                     WSIWHELTDADVSTIPYGRPLPGNRYFILDERQQHVPQGVVGRIYTVGVNLAQGYLENG
                     ELKQTDFVTINDDRGEPVRAFRTGDQGYYRQDGNIIFASRVNGYVKVRGVRVSLPDIEK
                     ELLKHPLIANAVVVDYLDGNGDSALAALFTLNSDKPLTAQQLRQFAQQCLPQSHIPTHF
                     MPMTILPLSANGKVDRKQCQARVVASLLPSESGTHAEREKGEVLKPTLLAQIEQIYRQV
                     IATDEVFDDAQELAFLSRGLLPSHLVSIASLLNQRFASQLSASQLVRCQSAQQVAALLA
                     "
     CDS_motif       complement(4765..4830)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0018"
                     /evalue="3.70E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="VV2_0831"
                     /protein_end="1342"
                     /protein_start="1320"
                     /score="13.3"
                     /tool="antismash"
                     /translation="FASRVNGYVKVRGVRVSLPDIE"
     aSDomain        complement(4795..5967)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VV2_0831_AMP-binding.1"
                     /evalue="1.90E-88"
                     /label="VV2_0831_AMP-binding.1"
                     /locus_tag="VV2_0831"
                     /protein_end="1332"
                     /protein_start="941"
                     /score="288.7"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="EANEKTAIICGENTVSYAELGSKVACVIGQLNVRGLQQGSVVAIC
                     LPRSVEHLVMTLACSLSGMVWVPIDASSPHDRLAYLLSNCNAELVVTQHGDVVASVAFS
                     ELLSPIASEAPLPSDEQLSCLSQSTQTAYYLYTSGTTGKPKCVVVNNQATSNVIGQTCR
                     EWSISSQDVIMSVTPYHHDMSVFDVFAAFSSGATLVLPGADGEKDALKWNQLIEQHKVT
                     IWVSVPAILEMLLSCTQGSQLQSLRLVAQGGDYIKPATIAQLRALESSIRLISLGGPTE
                     TTIWSIWHELTDADVSTIPYGRPLPGNRYFILDERQQHVPQGVVGRIYTVGVNLAQGYL
                     ENGELKQTDFVTINDDRGEPVRAFRTGDQGYYRQDGNIIFASRVNGYVKVR"
     aSModule        complement(4795..7317)
                     /domains="nrpspksdomains_VV2_0831_Heterocyclization.2"
                     /domains="nrpspksdomains_VV2_0831_AMP-binding.1"
                     /incomplete
                     /locus_tags="VV2_0831"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(4927..5007)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0017"
                     /evalue="1.30E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="VV2_0831"
                     /protein_end="1288"
                     /protein_start="1261"
                     /score="20.8"
                     /tool="antismash"
                     /translation="PQGVVGRIYTVGVNLAQGYLENGELKQ"
     CDS_motif       complement(5518..5574)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0016"
                     /evalue="1.50E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="VV2_0831"
                     /protein_end="1091"
                     /protein_start="1072"
                     /score="23.7"
                     /tool="antismash"
                     /translation="AYYLYTSGTTGKPKCVVVN"
     CDS_motif       complement(6205..6249)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0015"
                     /evalue="4.50E-02"
                     /label="Cy7"
                     /locus_tag="VV2_0831"
                     /protein_end="862"
                     /protein_start="847"
                     /score="7.2"
                     /tool="antismash"
                     /translation="VTQTPQMALDIRLTY"
     CDS_motif       complement(6295..6324)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0014"
                     /evalue="2.10E+00"
                     /label="Cy6"
                     /locus_tag="VV2_0831"
                     /protein_end="832"
                     /protein_start="822"
                     /score="2.2"
                     /tool="antismash"
                     /translation="LPVVITNGLS"
     CDS_motif       complement(6355..6399)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0013"
                     /evalue="5.00E-03"
                     /label="afterCy5"
                     /locus_tag="VV2_0831"
                     /protein_end="812"
                     /protein_start="797"
                     /score="10.0"
                     /tool="antismash"
                     /translation="ALEHLDFSGVDVNRL"
     aSDomain        complement(6520..7317)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VV2_0831_Heterocyclization.2"
                     /evalue="6.30E-33"
                     /label="VV2_0831_Heterocyclization.2"
                     /locus_tag="VV2_0831"
                     /protein_end="757"
                     /protein_start="491"
                     /score="106.3"
                     /tool="antismash"
                     /translation="PLSNLQKSYLLGRSTQIALGGVAMHEFREYRGNLATETVRENLTR
                     LVEQLPALRTHIDQDKLLQFVSPIIELNLKTFDFQHLSREKALLAVEPLREHYRHKMHD
                     LSGSPWEVCVVQLPPEYASRINTIIFTSFDALIVDGRSHSIILATLLGQQEDGIQDLLP
                     PRSPKRQGPVIDTAKRAQDERYWQEKLHRDCLPPALPWKQPLETIRTSRYARESLQIRR
                     AELQQLTLLGAENGLFVNSLLTAAIVQVLACWTTENGMRIGFPV"
     CDS_motif       complement(6553..6612)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0012"
                     /evalue="1.40E-02"
                     /label="Cy4"
                     /locus_tag="VV2_0831"
                     /protein_end="746"
                     /protein_start="726"
                     /score="8.6"
                     /tool="antismash"
                     /translation="GLFVNSLLTAAIVQVLACWT"
     CDS_motif       complement(6892..6933)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0011"
                     /evalue="2.30E-02"
                     /label="Cy3"
                     /locus_tag="VV2_0831"
                     /protein_end="633"
                     /protein_start="619"
                     /score="8.3"
                     /tool="antismash"
                     /translation="IFTSFDALIVDGRS"
     CDS_motif       complement(7138..7182)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0010"
                     /evalue="9.30E-01"
                     /label="Cy2"
                     /locus_tag="VV2_0831"
                     /protein_end="551"
                     /protein_start="536"
                     /score="2.6"
                     /tool="antismash"
                     /translation="LVEQLPALRTHIDQD"
     CDS_motif       complement(7279..7305)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0009"
                     /evalue="1.90E+00"
                     /label="Cy1"
                     /locus_tag="VV2_0831"
                     /protein_end="504"
                     /protein_start="495"
                     /score="2.4"
                     /tool="antismash"
                     /translation="LQKSYLLGR"
     CDS_motif       complement(7510..7554)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0008"
                     /evalue="4.80E-03"
                     /label="Cy7"
                     /locus_tag="VV2_0831"
                     /protein_end="427"
                     /protein_start="412"
                     /score="10.2"
                     /tool="antismash"
                     /translation="ISQGAQVTLDAQIAP"
     CDS_motif       complement(7618..7644)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0007"
                     /evalue="3.10E-02"
                     /label="Cy6"
                     /locus_tag="VV2_0831"
                     /protein_end="391"
                     /protein_start="382"
                     /score="7.5"
                     /tool="antismash"
                     /translation="PVVFTSGMD"
     CDS_motif       complement(7675..7719)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0006"
                     /evalue="1.50E-04"
                     /label="afterCy5"
                     /locus_tag="VV2_0831"
                     /protein_end="372"
                     /protein_start="357"
                     /score="14.6"
                     /tool="antismash"
                     /translation="LSHETYSGVQVMRDL"
     aSDomain        complement(7780..8679)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VV2_0831_Heterocyclization.1"
                     /evalue="5.90E-95"
                     /label="VV2_0831_Heterocyclization.1"
                     /locus_tag="VV2_0831"
                     /protein_end="337"
                     /protein_start="37"
                     /score="309.9"
                     /tool="antismash"
                     /translation="EMTAMQAAYWLGRQKGNAMEGLAAHLYAEFDGRDLNREALSMAVR
                     ALYAKHPMLRLAITAEGQQHILPLSACHQLTVEDIARYSKPEVEQFLHNKRERMSHQIL
                     DLNQSSPIEISVTLLANNEHRLHIDADMIACDAQSFRIVVEELARLYLSAQESDLVMSE
                     EPQITYFHYLDHQQADRYLAQRKASDKQWWQARLSSLPPEPPLPYLSHQDNEARPQTQR
                     LAHQFTHQERVALEALAKEHHLTLTQLFLALFSQVIATGAREHRFRLNVPTFHRGIYDP
                     QIEQAVGDFSNLLIFSAHV"
     CDS_motif       complement(7789..7839)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0005"
                     /evalue="6.30E-05"
                     /label="Cy5"
                     /locus_tag="VV2_0831"
                     /protein_end="334"
                     /protein_start="317"
                     /score="15.4"
                     /tool="antismash"
                     /translation="PQIEQAVGDFSNLLIFS"
     CDS_motif       complement(7903..7953)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0004"
                     /evalue="9.80E-03"
                     /label="Cy4"
                     /locus_tag="VV2_0831"
                     /protein_end="296"
                     /protein_start="279"
                     /score="9.1"
                     /tool="antismash"
                     /translation="HLTLTQLFLALFSQVIA"
     CDS_motif       complement(8263..8307)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0003"
                     /evalue="1.30E-04"
                     /label="Cy3"
                     /locus_tag="VV2_0831"
                     /protein_end="176"
                     /protein_start="161"
                     /score="15.2"
                     /tool="antismash"
                     /translation="RLHIDADMIACDAQS"
     CDS_motif       complement(8488..8541)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0002"
                     /evalue="6.40E-06"
                     /label="Cy2"
                     /locus_tag="VV2_0831"
                     /protein_end="101"
                     /protein_start="83"
                     /score="18.6"
                     /tool="antismash"
                     /translation="LYAKHPMLRLAITAEGQQ"
     CDS_motif       complement(8641..8667)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0831_0001"
                     /evalue="2.70E-02"
                     /label="Cy1"
                     /locus_tag="VV2_0831"
                     /protein_end="50"
                     /protein_start="41"
                     /score="7.6"
                     /tool="antismash"
                     /translation="MQAAYWLGR"
     gene            9016..10086
                     /locus_tag="VV2_0833"
     CDS             9016..10086
                     /EC_number="2.5.1.54"
                     /codon_start=1
                     /locus_tag="VV2_0833"
                     /note="COG0722"
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="AAO07756.1"
                     /transl_table=11
                     /translation="MPTLSKLIHSTPCGTLPSVEEIIQHASLDEESEAFIRQRRQDITR
                     ILNGQDPRLLVIIGPCSIHDPQAGLEYAQKLANIQHQHEKQLLIVMRTYFEKPRTRAGW
                     KGLIVDPDLDNSHDINKGLRLARQFLQQVIKLGLATATEYLDTTTYPYISDLICWGAIG
                     ARTTESQIHRQMASALPCPIGFKNGTDGNVDIAIDAIHAANSPHLICVPGFGARTLTAI
                     SHGNPNGHIILRGGKTPNYTTEHVCQISQQLEANDLNPRLIIDCSHGNSLKVAKNQLDV
                     ARNIACQLIEGEKCIAGVMAESFLVAGAQKITDRPLVKGMSITDECLGWEETESILNIF
                     AEAVNVVMTERFSTVA"
     gene            complement(10318..11106)
                     /locus_tag="VV2_0834"
     CDS             complement(10318..11106)
                     /EC_number="1.3.1.28"
                     /NRPS_PKS="Domain: PKS_KR (9-171). E-value: 5.8e-12. Score:
                     37.7. Matches aSDomain: nrpspksdomains_VV2_0834_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: EntA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     230.4; E-value: 3.8e-70)"
                     /gene_kind="biosynthetic"
                     /locus_tag="VV2_0834"
                     /note="COG1028"
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase"
                     /protein_id="AAO07757.1"
                     /sec_met_domain="EntA (E-value: 8.2e-115, bitscore: 372.8,
                     seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1e-31, bitscore:
                     100.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 6.3e-39, bitscore:
                     124.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFNQFLEKQTVFLTGAAKGIGFSVMQHLLEAGARVVATDIDEVRL
                     KTDSDALKNRYREQLFCYHLDLSQPESVARRVAQMIEQHGQFDHLVCCAGVLHLGSITS
                     MPLAQIEHTFNVNTFGTLAVMQALAEGMKARRSGSMVIVGSNAANTPRPNMGAYGASKA
                     ALHMLVKSMGMELAEYGVRCNIVSPGSTRTDMQMQLWSEEYGEPQVIAGNLEQFRLGIP
                     LRKMAEPQDIARSVLFLLSEHAGHITLHDLRVDGGATLDN"
     aSDomain        complement(10594..11079)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VV2_0834_PKS_KR.1"
                     /evalue="5.80E-12"
                     /label="VV2_0834_PKS_KR.1"
                     /locus_tag="VV2_0834"
                     /protein_end="171"
                     /protein_start="9"
                     /score="37.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TVFLTGAAKGIGFSVMQHLLEAGARVVATDIDEVRLKTDSDALKN
                     RYREQLFCYHLDLSQPESVARRVAQMIEQHGQFDHLVCCAGVLHLGSITSMPLAQIEHT
                     FNVNTFGTLAVMQALAEGMKARRSGSMVIVGSNAANTPRPNMGAYGASKAALHMLVKS"
     CDS_motif       complement(10999..11079)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0834_0001"
                     /evalue="7.10E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="VV2_0834"
                     /protein_end="36"
                     /protein_start="9"
                     /score="18.7"
                     /tool="antismash"
                     /translation="TVFLTGAAKGIGFSVMQHLLEAGARVV"
     gene            11478..12659
                     /locus_tag="VV2_0835"
     CDS             11478..12659
                     /EC_number="5.4.4.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: EntC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 371.8; E-value:
                     1e-112)"
                     /gene_kind="biosynthetic"
                     /locus_tag="VV2_0835"
                     /note="COG1169"
                     /product="Isochorismate synthase"
                     /protein_id="AAO07758.1"
                     /sec_met_domain="EntC (E-value: 4.4e-150, bitscore: 490.4,
                     seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKREVIGYTKMANELLDNELSSSPFFFASPNNTMMGIGVQEERLQ
                     TLPFSELADVANNMLKNAKTSESDNPVLFGVVPFNQENMTRFVIPKTLYISSSTRASHT
                     SASSAPQARLISSPSGHHYKQGVHDLLGMFANQELSKVVLSRAIEVATETDIQQQALLR
                     NLLSINAKGYTFAAQIGDNQKLMGASPELLVAKKGSHLISNPLAGSRPRSESEQQNQAS
                     IQSLLNTGKDLHEHGLVVEEVERVMSKYCCNLYTPMVPSVIETQTMLHLSTQLEGQVLD
                     PAINVLQVAAELHPTPAVCGYPREKAYEAIKRLEQFDRGYFTGMVGWCDSRGNGEWVVT
                     IRCAEVQPRRMKVFAGAGIVNESQPQSELDETGAKMNTILKAAGIQLNEMLTA"
     gene            12669..14306
                     /locus_tag="VV2_0836"
     CDS             12669..14306
                     /EC_number="2.7.7.58"
                     /NRPS_PKS="Domain: AMP-binding (39-443). E-value: 3.8e-79.
                     Score: 258.0. Matches aSDomain:
                     nrpspksdomains_VV2_0836_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     432.2; E-value: 3.5e-131)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="VV2_0836"
                     /note="COG1021"
                     /product="2,3-dihydroxybenzoate-AMP ligase"
                     /protein_id="AAO07759.1"
                     /sec_met_domain="AMP-binding (E-value: 3.9e-91, bitscore:
                     295.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSVQSDFTPWPEQMADDYRRLGLWQDKTLYQYLKQSIIRYPTNI
                     AIVCRQQSITYAELERKIHAAANGFRSLGLAEGDNVILQMTNIAEFYVSYFALIHQGIR
                     PILALPAHRHAEISYFCQHAQAKAYLIDGQTRGFDYQTLAEKLLKEHPCLRHVIVRANH
                     SELLQSHFISFDDFRDERELAPVSNASQVAFFQLSGGTTGTPKLIPRTHNDYAYSVVGS
                     NAICGFNEYTRYLCALPAAHNFPLSSPGSLGVFFAGGTVVLTQDPTPKAAFPLIERHKV
                     TVSALVPPLALLWMDAAPHARYNLSSLQLIQVGGAKLSQSAAKALPKALNCQLQQVFGM
                     AEGLVNYTRLDDPLEVIIETQGRPISAHDQVKVVNEAGEEVACGEEGFLLTQGPYTIRG
                     YYRAPEHNQRSFTHNGFYRTGDIVKITEQGNIIVTGRDKDQINRGGEKIAAEEVENHLL
                     GHSAIHDVALIAIPDRLLGERSCAVIVTKRHLNITGTELKRYLRSKGLADYKIPDVIQF
                     ADALPKTSVGKIDKKRLRESYAQLGLSA"
     aSDomain        12786..13997
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VV2_0836_AMP-binding.1"
                     /evalue="3.80E-79"
                     /label="VV2_0836_AMP-binding.1"
                     /locus_tag="VV2_0836"
                     /protein_end="443"
                     /protein_start="39"
                     /score="258.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RYPTNIAIVCRQQSITYAELERKIHAAANGFRSLGLAEGDNVILQ
                     MTNIAEFYVSYFALIHQGIRPILALPAHRHAEISYFCQHAQAKAYLIDGQTRGFDYQTL
                     AEKLLKEHPCLRHVIVRANHSELLQSHFISFDDFRDERELAPVSNASQVAFFQLSGGTT
                     GTPKLIPRTHNDYAYSVVGSNAICGFNEYTRYLCALPAAHNFPLSSPGSLGVFFAGGTV
                     VLTQDPTPKAAFPLIERHKVTVSALVPPLALLWMDAAPHARYNLSSLQLIQVGGAKLSQ
                     SAAKALPKALNCQLQQVFGMAEGLVNYTRLDDPLEVIIETQGRPISAHDQVKVVNEAGE
                     EVACGEEGFLLTQGPYTIRGYYRAPEHNQRSFTHNGFYRTGDIVKITEQGNIIVTGRDK
                     DQINR"
     gene            complement(14425..15240)
                     /locus_tag="VV2_0837"
     CDS             complement(14425..15240)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200:vibriobactin
                     utilization protein ViuB (Score: 264.1; E-value: 1.9e-80)"
                     /gene_kind="other"
                     /locus_tag="VV2_0837"
                     /note="COG2375"
                     /product="Vulnibactin utilization protein VuuB"
                     /protein_id="AAO07760.1"
                     /transl_table=11
                     /translation="MSDSPERVYPMLLDFVRKETISKNLLRVTLTGEDLIGFPEDQNGS
                     HIKVFFPNQASGILQLPVREGDNVIWPEHKPVPRAYSVRQYRAAVNELDIDFVTHGEET
                     PGGGWALKADIGSQIGLIGPAGPDPLIEPADWHIIAGDLSAVPAISAILEKLPSDAKGY
                     VFIEVDEIEDIHDLVHPEEMAINWLMRNPHDAEPALAKAIKQLPSPEKATSLSAFIAGE
                     NQSVINCRKILRNDYQIARDKLYAIPYWKRGKTEEAYHDERHDVMDAVY"
     gene            complement(15304..16191)
                     /locus_tag="VV2_0838"
     CDS             complement(15304..16191)
                     /EC_number="3.3.2.1"
                     /NRPS_PKS="Domain: PP-binding (217-277). E-value: 8.7e-11.
                     Score: 34.1. Matches aSDomain:
                     nrpspksdomains_VV2_0838_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:isochorismatase (Score: 338.4; E-value:
                     3.8e-103)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="VV2_0838"
                     /product="Isochorismatase"
                     /protein_id="AAO07761.1"
                     /sec_met_domain="PP-binding (E-value: 2.5e-11, bitscore:
                     34.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIPKIAGYPLPTPAEFPDNRTGWTIDPDQAVLLIHDMQEYFVNY
                     YQPDSSPVVDIIQHIQRLKAAAKKAGIPVIYTAQPANQHPTDRALLTDFWGPGLNGDHV
                     PIVEALSPEEGDIEYVKWRYSAFKKTPLLEFMRAQGKSQLIISGIYGHIGILSTTLDAF
                     MLDIQPFVIGDAIADFTREDHLRTLEYVASRSGSVKRLDEALDEIRSQKPLTLEQIQQD
                     VATSLGIQPDEVDLDEDLMFVGLDSMRAMVLVEKWHQQGENISFGQLMEAASLREWWLV
                     IEQARNEEQTMAVA"
     aSDomain        complement(15361..15540)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VV2_0838_PP-binding.1"
                     /evalue="8.70E-11"
                     /label="VV2_0838_PP-binding.1"
                     /locus_tag="VV2_0838"
                     /protein_end="277"
                     /protein_start="217"
                     /score="34.1"
                     /tool="antismash"
                     /translation="QIQQDVATSLGIQPDEVDLDEDLMFVGLDSMRAMVLVEKWHQQGE
                     NISFGQLMEAASLRE"
     gene            complement(16294..16623)
                     /locus_tag="VV2_0839"
     CDS             complement(16294..16623)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: IPL"
                     /gene_kind="biosynthetic"
                     /locus_tag="VV2_0839"
                     /note="COG1605"
                     /product="Isochorismate pyruvate-lyase of siderophore
                     biosynthesis Vulnibactin-specific"
                     /protein_id="AAO07762.1"
                     /sec_met_domain="IPL (E-value: 4.8e-55, bitscore: 174.2,
                     seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASLKKPEACESLNDIRLGIDTLDKEIVHILSQRMGYVKAAAQFK
                     PDEKSIPAPERVASMLEERRHWANEQGLSEEYVEALFDNIIQWYISQQIQHWRSQKGLA
                     PVSQD"
     gene            complement(16852..18480)
                     /locus_tag="VV2_0840"
     CDS             complement(16852..18480)
                     /EC_number="2.7.7.58"
                     /NRPS_PKS="Domain: AMP-binding (44-446). E-value: 2.7e-81.
                     Score: 265.1. Matches aSDomain:
                     nrpspksdomains_VV2_0840_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     423.4; E-value: 1.6e-128)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="VV2_0840"
                     /note="COG1021"
                     /product="2,3-dihydroxybenzoate-AMP ligase"
                     /protein_id="AAO07763.1"
                     /sec_met_domain="AMP-binding (E-value: 4.4e-90, bitscore:
                     292.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVATTETPKQILDGFVRKPSIQREQYQAANLWRNLPLWQILHQG
                     VERHPDRIAVTDNHTSLSYLELANHVDRIAAGLREEGLVCGDSVVLQLANTLDFLVVFF
                     ALQRLGVVPVLALPAHGLVEIRHFMQLSEAKVYIGSNHEKDDKALAIATQLQAELSVSI
                     RCYISGHFGQFSPLPECDAGDFTPAMVDPEHPALFLVSGGTTGLPKLIPRTHNDYLFNV
                     EQCAKASEISAQDVYLAVLPAAHNFTLGCPGILGVLNAGGKVVLTTNPSPDYCFELIEK
                     QCITATALVPALAQLWTEATQWESTDRSSLRLMQVGGSKLAYSDALEMQNAFPNALQQV
                     FGMAEGLIACTRLGDDKEIIATRQGRPVSEWDEVLVVDDQGKPVAIGEEGELLTRGPYT
                     LSGYYRAPEHNLRAFTDEGYYRSGDRVVVDANGYFTVTGRIKDVIIRAGENIAADELEE
                     LLLSHPQIAQVAVFPLPDAHLGEKIAVAAVIRGPEIMLRDIRQFLQTKEIAAFKLPDEL
                     FAVKSLPKTAVGKIDKKRILSTILP"
     aSDomain        complement(17143..18348)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VV2_0840_AMP-binding.1"
                     /evalue="2.70E-81"
                     /label="VV2_0840_AMP-binding.1"
                     /locus_tag="VV2_0840"
                     /protein_end="446"
                     /protein_start="44"
                     /score="265.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="GVERHPDRIAVTDNHTSLSYLELANHVDRIAAGLREEGLVCGDSV
                     VLQLANTLDFLVVFFALQRLGVVPVLALPAHGLVEIRHFMQLSEAKVYIGSNHEKDDKA
                     LAIATQLQAELSVSIRCYISGHFGQFSPLPECDAGDFTPAMVDPEHPALFLVSGGTTGL
                     PKLIPRTHNDYLFNVEQCAKASEISAQDVYLAVLPAAHNFTLGCPGILGVLNAGGKVVL
                     TTNPSPDYCFELIEKQCITATALVPALAQLWTEATQWESTDRSSLRLMQVGGSKLAYSD
                     ALEMQNAFPNALQQVFGMAEGLIACTRLGDDKEIIATRQGRPVSEWDEVLVVDDQGKPV
                     AIGEEGELLTRGPYTLSGYYRAPEHNLRAFTDEGYYRSGDRVVVDANGYFTVTGRIKDV
                     IIR"
     gene            18706..18948
                     /locus_tag="VV2_0841"
     CDS             18706..18948
                     /NRPS_PKS="Domain: PP-binding (9-68). E-value: 2.8e-16.
                     Score: 51.7. Matches aSDomain:
                     nrpspksdomains_VV2_0841_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="VV2_0841"
                     /note="COG3433"
                     /product="Aryl carrier domain protein"
                     /protein_id="AAO07764.1"
                     /sec_met_domain="PP-binding (E-value: 8e-17, bitscore:
                     51.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEPLKEFDLLATLSELLRVSEAEIQSDTNLIELGLDSISLMRLT
                     GRLRQVGIEVNFAQLMNSPTFSSWQTIIFNAKALA"
     aSDomain        18733..18909
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VV2_0841_PP-binding.1"
                     /evalue="2.80E-16"
                     /label="VV2_0841_PP-binding.1"
                     /locus_tag="VV2_0841"
                     /protein_end="68"
                     /protein_start="9"
                     /score="51.7"
                     /tool="antismash"
                     /translation="LLATLSELLRVSEAEIQSDTNLIELGLDSISLMRLTGRLRQVGIE
                     VNFAQLMNSPTFSS"
     gene            19004..19912
                     /locus_tag="VV2_0842"
     CDS             19004..19912
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 220.5; E-value:
                     4.2e-67)"
                     /gene_kind="transport"
                     /locus_tag="VV2_0842"
                     /note="COG4607"
                     /product="ABC-type enterochelin transport system,
                     periplasmic component"
                     /protein_id="AAO07765.2"
                     /transl_table=11
                     /translation="MKLKLSVMLVSTLISGGAMAKDLVIEHYMGSTKISDAPKRVVVIG
                     HGALDALDYLGIEPVAVAKAPIMPQYLDKFQDAKYASAGSLFEPDFETIYSQKPDLIII
                     GPRATSKYKELSEIAPTIVFSADLKQGYWQSTQKQWRNMGEIFNAQQKIEQKISQLNEE
                     FAAIKQYNEKNQVDALTIMTSGGNITTFGSQSRFASVYEDFGFKESSSNVKTNNHGDII
                     SYEYINKANPSTLLVIDGDKLSGKGNQVEEQYLDNDLVKATNAYKNKRITLLDLDAWYL
                     SISGISATEKMVSDIKETVEL"
     gene            complement(19997..22054)
                     /locus_tag="VV2_0843"
     CDS             complement(19997..22054)
                     /codon_start=1
                     /gene_functions="transport (smcogs)
                     SMCOG1107:TonB-dependent receptor (Score: 621; E-value:
                     4.1e-188)"
                     /gene_kind="transport"
                     /locus_tag="VV2_0843"
                     /note="COG1629"
                     /product="Ferric vulnibactin receptor VuuA"
                     /protein_id="AAO07766.1"
                     /transl_table=11
                     /translation="MAALRPARTSVAEKKTFKLHALSAVVMGLCASGQAYAQTESTNSN
                     KKEEMPVVVVIGEKTERTIYDTSSSVQVFDQETIDNTPGATEIDDLLQLIPNMVDSGQG
                     NSMPTVRGIDGSGPSVGGLASFAGTSPRLNMSIDGRSLTYSEIAFGPRSLWDMQQVEVY
                     LGPQSYIQGGNSSAGAIVMKTNDPTHHFESAVKAGIGERNYSQTAAMISAPIIQDELAF
                     RLSFDQQKKESFVGLAAYDPAGESSRIEMSSLRGKLLYEPSSMDGFKTTLGVSLMDSRS
                     PQSESINIEGANAFRAVFETSSLSTVWDVSWQLNDQFTFESNVVYADFTNERLTYPVDK
                     FDFSTSGSEYHVEPILKYLSSNGRLSALFGARYYSSKQNESFTTTSGSNPMKGSKDTQS
                     LFAEMTYAITQSIDVTLAGRYEKEHITRKVEVFNIDYDETLGVFLPKFDIAYKPANDQT
                     FGFKVAKGYNAGGAGLGFNSITSGGFKPYEFKEEYLWNYEFYTRHRLGHSLELLTNTFY
                     NDFDDMQMTQLLANGDVFITNLDEAKTYGVEVGTRWYATDSLELFANLGLLKTEYKEVN
                     GTSKELERAPNITGNLGGQYSFFDGFELSANAAYTGDYYSDRSNTAITTIDAYWVANAQ
                     LAYVFENGRATLFATNLFDSNKTTLYTSSNLNDQLTQQPRMIGASLQLNF"
     gene            complement(22395..23711)
                     /locus_tag="VV2_0844"
     CDS             complement(22395..23711)
                     /NRPS_PKS="Domain: Condensation_Starter (16-314). E-value:
                     4e-58. Score: 188.9. Matches aSDomain:
                     nrpspksdomains_VV2_0844_Condensation_Starter.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: VibH_like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     314; E-value: 3.3e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="VV2_0844"
                     /note="COG1020"
                     /product="Amide synthase component of siderophore
                     synthetase Vulnibactin-specific"
                     /protein_id="AAO07767.2"
                     /sec_met_domain="Condensation (E-value: 5.7e-32, bitscore:
                     101.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="VibH_like (E-value: 1.5e-170, bitscore:
                     557.3, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFYLLLRFDRQMSKPVFFPLSLAQQEYWADYIAFPERPFSNVAHG
                     IEISGECDIECLYQAILETTQEAEALRLCFGCDEQGYPRQVVLDCSAIVLDCINLIDEA
                     EAEQLAWQKIRDDIAKPIDLTGEVMTYQAIFRLSEVKTLWYIRSHHIALDGYSLHLIEQ
                     RCASLYSAFIQSQTLPVVFKGFNTYVRNEQAYLCSERAEKDQRFWLDYINQHSFISFND
                     DDFNNDTFAIAKEVDPELRAALLNVSQQQQWAWVDLLVVLVGLYCVEKQVLTEQQSASD
                     GLWIWLPYLNRMGNRCANTPCLMVNTLPLWINADIEENFVDRVKRLMAELRLLYRHGKH
                     PLSNSLNVKASQSPYINVLIDEDIVFGGCQSERKVVANGTNDGLNMTFRVRKDAANITF
                     TVEGEQRWFGQEQITHLSEQLMVFMHQSLNTLAEQNSGQ"
     aSDomain        complement(22770..23663)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VV2_0844_Condensation_Starter.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="4.00E-58"
                     /label="VV2_0844_Condensation_Starter.1"
                     /locus_tag="VV2_0844"
                     /protein_end="314"
                     /protein_start="16"
                     /score="188.9"
                     /tool="antismash"
                     /translation="FFPLSLAQQEYWADYIAFPERPFSNVAHGIEISGECDIECLYQAI
                     LETTQEAEALRLCFGCDEQGYPRQVVLDCSAIVLDCINLIDEAEAEQLAWQKIRDDIAK
                     PIDLTGEVMTYQAIFRLSEVKTLWYIRSHHIALDGYSLHLIEQRCASLYSAFIQSQTLP
                     VVFKGFNTYVRNEQAYLCSERAEKDQRFWLDYINQHSFISFNDDDFNNDTFAIAKEVDP
                     ELRAALLNVSQQQQWAWVDLLVVLVGLYCVEKQVLTEQQSASDGLWIWLPYLNRMGNRC
                     ANTPCLMVNTLPLWINA"
     CDS_motif       complement(22782..22853)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0844_0003"
                     /evalue="2.10E-06"
                     /label="C5_starter_265-294"
                     /locus_tag="VV2_0844"
                     /protein_end="310"
                     /protein_start="286"
                     /score="20.2"
                     /tool="antismash"
                     /translation="LPYLNRMGNRCANTPCLMVNTLPL"
     CDS_motif       complement(23205..23267)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0844_0002"
                     /evalue="2.20E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="VV2_0844"
                     /protein_end="169"
                     /protein_start="148"
                     /score="23.7"
                     /tool="antismash"
                     /translation="HHIALDGYSLHLIEQRCASLY"
     CDS_motif       complement(23484..23594)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VV2_0844_0001"
                     /evalue="1.20E-09"
                     /label="C2_starter_024-063"
                     /locus_tag="VV2_0844"
                     /protein_end="76"
                     /protein_start="39"
                     /score="30.8"
                     /tool="antismash"
                     /translation="SNVAHGIEISGECDIECLYQAILETTQEAEALRLCFG"
ORIGIN
        1 atgaaactag ataaagtgga aaacaaaaat cgccgcctac gtaaaaaact ctttttaggt
       61 gaattcgcta ttctcggttt cgagatcagc tgtgaaaccg atattcacga ctttgatcgt
      121 tacgacgtgt tcgttgatga cttcattgat tttattgacg caaaaggcct atgttttggc
      181 ggtggcggtc ttgagcactt tgaaggtttc atctgtgcga aagagcgtta cgaaagcgcg
      241 actgaagaac agcgcgcagc agtcgtagaa tggctgaacg cacgtgcaga agtgaaatct
      301 gtattggtaa gtgacctagc agatgcgaac tacttataat tcgcagcgga atgaagaaac
      361 ggcccatcat gggccgtttt tgttttggct taaagtgttt gatcgttttc actcactagg
      421 gtgaccacac tgtcatcatg cagatgaaaa aaagccgtaa accgctgctg aagcatgttt
      481 tgctctgccc ctcgacaaag acataacgcc agcttaccgc gatgaagatc cacctcctct
      541 acgtaggaat gggagaactc caagtaacga ccgacggtcg ggtaaatcgc tttaaataag
      601 ctttctttgg cagaaaaaac caaggacact aaacgatgga ttggccaatc cgtcgctgct
      661 accaaagccc gctcttgtgg tgtcaccaaa atcagcggca tgatttcctt cgcagcacgt
      721 tcactgacaa atttctccat atcaacacca agttttgcat gttcatgcat tttactaacc
      781 acgcaaatcg cagtgtgatc ggtatgcgat atactaccaa gccatcctga cggccattgt
      841 ggcgctcggt gctcccccac acagacgtga tatgaaggac ttttaagcgc cactaacgca
      901 tcacgcgcaa ccacgcgccc agcaacaaac tccgcccgac gcttgcagct tgcttgctga
      961 agtgaatctg gcaccgcgat ctgccacgct tgcgcactgt tgggctcaaa gctagacgca
     1021 tcaaactgac gctgccaaac cgtgtgccca cctaagctca acgtggtggg gtctgagagc
     1081 cgcatcggtt tacgcgcctt cgtgtgccag acaggccgtt gcttctagcg ccgccacttg
     1141 ttcttgtagc tgagccaaat cctgatcttg cgcgacgcaa ccagcgaaca cctcaaacaa
     1201 gcgacgattg acgtccgaaa gcagtgtcac ttgagctgga ctgtaatttt tgttcatgta
     1261 actcatcatc acgcgcagag tttgctcgcc atcaatgctc tcttccatga cttcaaactg
     1321 cagccccaaa cccgattcac ttttgtctgg atcaacttgc tggaagcgga cacgctcgtt
     1381 ttcagacagt tcaaacgcac catgaaactt gttcttggcg tgcaattgaa tgaagacttc
     1441 aaacatgtgt ccttcggtgt cgtggtcaac cccttttaag ccctcttcaa tcaaatcgat
     1501 aggaatatcc gtgtaggcca tggattcatt gatgctgttt tttacctgct caatcaactg
     1561 ccagatggat ttgaccccgg cgaaatcaac caattgcacg cctagcgtag tgaaataccc
     1621 gaccgtatca aagtagtctg cgtccaaacg gccagcagcg ggtgtgccga cgatcagttt
     1681 ttcaggcgca ccaagtaagc gtaatgaagc ggcaatagcg gcatacacca cgttgaacag
     1741 cgacgcactg cgcgctttag ccaaagcata cagctggctg ctgactcgct gcggaatttt
     1801 gatttctacc caaccgcctt caccacattc gacctgttgt tcaacactta acggatgatg
     1861 agcgggaaaa atcggctccg cccaaggcag cccttcaaat ttgttcagcc agtaggataa
     1921 atgcgcttgg ttaacatcgg aggcacgttg ttttctggcg aattcatgga acggtcgtgg
     1981 ctgcatgtgc cacagcggtt cgtgaccttg aacataacat cgataggcca gcgccagttc
     2041 atccatcatg gtatttaacg accactcatc cagtacgatg tgatggaaca acagagacaa
     2101 gtactgtgct ccgtcagcat cgtccgtcac aaacctcagc cgcaatggca attcgttgtc
     2161 cagatcaaac gcgtactcgg cttcttgcgc tagaaggtcg ctaaccgaca atcctccatt
     2221 ttgctgcgag gtccaaaacc attgatactc tgtcagtttt tctaccggaa tcacttgctg
     2281 atatggctgg ttgtcttcgg tggaaaaccg cgtacgcagc ccagtgtggc gcagcaaaat
     2341 ctcatggaaa gcccggccaa atgccgcttc atcaacacga tccaaaaact tcagtgcaaa
     2401 cggcaaattg aagatattgt tgagaccaac gctggcgtat ttgctcatcg ctttccacaa
     2461 tgaatgttgc gccaatgaca aaggtgctct gtccaatgcg atgggattgt gttgcgattg
     2521 tgcagttgcc ttggcttcgc agtgagacgg ctgatgcacg accgcctgtt gcactttcgc
     2581 ctgttgcact ttcgcctgtc gagccaactg tttcgcactc gggaagctga acatgtcgtt
     2641 gatgtggatt tctatgccat gatccgatag cagtcgacca attactctgg tcgcgatgag
     2701 ggagtggcca ccaaaatcaa aaaagtcatc gtctgctgtc atcgtttggt tcgcaagtgc
     2761 cgttcgaaac tctgccagga tcgccgcttc caccgccgct tgtgtttgtt catgagtttg
     2821 gctcgtggtg tcactgacgt ttgctggctc gcggttgtca gactcatgca aatgcaacga
     2881 gctagcggct ttgcctccaa tctgggcgac aaactgctca agcataaagg caccaatgta
     2941 tggcgatgcg ccagcggcca gtgtcagttc cagcaccaat gctccctgac agttaaggcc
     3001 aacacctaac gttaccgcaa atttgggatg tgccgcggca aacaaagatt tttcggcgtt
     3061 gacctgatcc aattgcagat gcaccgaagg atccaccagc caagtaacaa gggcagcctc
     3121 ttgttgacca tgataggagg ccgcataatg ctcgcggctt tggttgagct gcgccagtat
     3181 ttccgcactg ttacgctcaa tcggggcgga tacatgagga accttgatcg caattaaccc
     3241 tgtttcaatc atcgccccat taagctcaaa cgctcgacgt tccacatcat aaggcagata
     3301 taagtcgcac tgatcagtgt tggcgttgac cgctaaatag cgagcaaaca gtgcggcaat
     3361 gacggaaagc acctcttttt tattcggttg agacaaccca tagtcatcca gcacactgcc
     3421 ttgcaaagaa acacgatact tacgagcaag catcgggtgc tcgggtgaat cctttggcgt
     3481 cgctggccaa ctttgctcga ccacaagttc aggctgcgca ctttgcagcc atgcaaagca
     3541 agtattgccg atatcacttt gaggtgtgag gggcgtatag ccgatatgag cgctttggcc
     3601 cggtgaagcc ccttcccaat cgcgtttcaa cgacggctgg ttgtagcgca cactcaaacg
     3661 ctgaaacaca ctttgccaat ccattcgctc actgaggatc tggtgcgtca cgacgccaag
     3721 cacgacgccg tcaatgtcac cgctgtacaa gacaaatcga atcggcgcat cgtcatctag
     3781 ggctataggt tggttttgca acgccattaa atactgcatc gcctgctcga gtgaaacgac
     3841 ttgttcgata tcaacacgga gtaaactcgc gtcaacccct tgcttagtca gacctaacgc
     3901 atcattaaac aggtagcgct gattgaatat gggaaaatct tgcgacaact gagaaagcgc
     3961 agccaccaat ttacccatgt tcacttcacc agtcagatgg taagcggaag catactggtt
     4021 acgcccatca ccatgttgtt gatgatacag ccaaactcgt tgctcaaact cgctcacacc
     4081 aagcgatggt tcaatggttt gttgtaggat accgtctcga tgggcttcca gcttggaaac
     4141 atccaggtta agcgtcatat tcctttctcc aaaaggcgcc attgcgccat ttcacggcga
     4201 taaaatcggt taataaatta gggctggcta tgcgagtaaa gccgcaacct gttgcgcaga
     4261 ttgacagcga accaactgcg aggcgctcaa ctggctagca aagcgttgat tcaaaagtga
     4321 agcaatgctg acaaggtgag atggaagtaa tcccctcgac aaaaatgcca actcttgcgc
     4381 atcatcgaag acctcatctg tcgcgatcac ttggcgataa atctgttcaa tctgtgcaag
     4441 tagagttggc ttcagcactt cccctttttc acgctcggca tgtgttccgg attcgctcgg
     4501 cagtaaggag gcaaccactc gcgcttgaca ctgctttcta tccactttgc cattggcgga
     4561 aagaggcaaa atggtcatcg gcataaagtg ggttgggatg tgcgattgag gcaaacattg
     4621 ctgagcaaac tggcgcagtt gctgagcagt cagcggctta tctgaattca gagtaaagag
     4681 cgccgccaaa gcactgtccc cattgccatc gagataatcg acgacaaccg cattggcgat
     4741 caaaggatgc ttcaacagct ctttttcgat atccggcaaa gagactcgca ccccacgaac
     4801 tttgacgtaa ccattcactc ggctagcaaa aatgatgttg ccatcttgtc ggtagtaacc
     4861 ttggtcaccg gttcgaaacg cgcgtacagg ctcgccacga tcatcattga tggtgacaaa
     4921 atccgtctgc ttcagctcac cattctctaa atagccttgt gctaagttga ccccgacggt
     4981 gtaaatgcgc ccgaccaccc cttgaggcac atgctgctgc ctctcatcca aaatgaaata
     5041 gcgattcccg ggcagtggcc gtccataagg aatggtcgac acatccgcat ccgtcagctc
     5101 atgccaaata ctccaaatgg tggtttctgt cggtccgcca agcgaaatca aacggatcga
     5161 actctccagt gcgcgcagtt gagcaatggt cgcaggctta atgtagtcgc ccccttgggc
     5221 aaccaaacgc aacgattgca gttgcgagcc ttgcgtgcaa gaaagcagca tttccaaaat
     5281 cgctggcacc gacacccaaa tcgtcacctt atgctgctca atcaattggt tccatttcag
     5341 cgcatctttt tcaccatcgg ctcctggaag caccagcgtc gccccggagc taaaagccgc
     5401 aaacacgtca aacaccgaca tatcgtggtg atacggtgtc acggacatga tcacatcctg
     5461 cgacgaaatc gaccactcac ggcaggtttg accaatgaca ttggacgtcg cttgattatt
     5521 gaccaccacg catttcggtt tgccagtggt gcccgaggta tacagatagt aggccgtttg
     5581 ggtgctttga cttaagcacg ataactgttc atcactcggc aacggagcct cacttgcgat
     5641 ggggctgagg agctctgaga aggcaaccga cgccacaacg tcaccgtgtt gcgtgaccac
     5701 cagttctgca ttgcaattac tgagcagata agccaaacgg tcatgaggtg aggatgcatc
     5761 aatgggcacc cataccatgc ccgacagtga gcatgccaac gtcatcacca agtgctccac
     5821 acttcgtgga agacagatag ccaccacact gccttgttgc aaccctctga cattaagctg
     5881 gcctatcaca caagcgactt tcgagcccaa ttctgcatac gagaccgtgt tttcaccaca
     5941 aatgatcgcc gttttttcat tggcttcatc aaacagttga cgcgcaatgt gcgacaagaa
     6001 atccgaaggg tcacgctgag tttcatcgct attgaggcga tagtgggaaa gatcaagaaa
     6061 agacgatgac ggtaagagtc cttgctggga ttcagacagt tgttgcaaca acgttttgag
     6121 cgcattaaga atatcgcaca caacgtttgt ctccagcgca tccaccgcgt aatcgaagct
     6181 gacgatgaga tttttctgct catcgtacgt cagtcgaatg tccaatgcca tttgcggtgt
     6241 ctgagtcacc ccagaaaaga gcgccacatc gtcggtttct ttgagcgtct gccacgataa
     6301 gccattagtg atcaccacgg gcaatgctaa tgcgggtgaa gagccattca tcaataggcg
     6361 gtttacgtcc acccccgaga aatcgaggtg ttccagcgct tcaagcatat ccgattgcaa
     6421 atcaagagct tgactcagca cagaggcgtc cgatttttca tgctccaaaa tcacaaaagt
     6481 cgattcattg cccgccaact catcttgctg cggtatcacc accggaaaac caattcgcat
     6541 accattttcg gttgtccagc aggccaacac ttgtacgatg gcggcggtca acaatgagtt
     6601 gacgaacaaa ccattttccg ccccaagcag ggtcagttgt tgcagctcag cacggcgaat
     6661 ttgcaagctt tctcgcgcat aacgagaagt gcggatggtc tccagcggtt gtttccaagg
     6721 caatgccggg ggcaagcagt cacgatgcaa tttttcttgc caatagcgtt cgtcttgcgc
     6781 tcgtttcgcc gtatcgatga cgggcccttg acgctttggt gagcgagggg gcagcaaatc
     6841 ttgaatgcca tcttcttgct gaccaagcag cgttgcgaga atgatcgaat gactgcgccc
     6901 atcaacaatc agggcatcaa aactggtgaa aataatggtg tttattcgac tggcgtactc
     6961 tgggggcaat tgaacgacac acacctccca aggcgaaccg cttaaatcgt gcattttatg
     7021 gcgatagtgc tcgcgaagtg gctccaccgc taaaagtgct ttttcacgag aaagatgctg
     7081 aaaatcaaac gtttttaaat tgagttcaat gatgggagaa acaaactgca gcaatttatc
     7141 ttggtcgatg tgcgtcctca acgccgggag ctgttcaacc aagcgggtga gattttctcg
     7201 caccgtctcg gttgctaaat tgccgcgata ttcgcgaaac tcatgcatcg caacgccacc
     7261 taaggcaatt tgagttgaac gccctaacaa atacgatttc tgcaagttgc tcaatggtgt
     7321 cgccgctata tttttcgact cggattgccc caatgccgcg tctagctgtt cgagcgtctg
     7381 atgcatgatt tgtgggaacg tcgcaaggcg gcgaatcaac gcaacgtaat gagcaaacat
     7441 ggactcaatc acctcttgct ccaaaagatc cgaacgaata tcccagttag ctaaaatgcc
     7501 gccataagca ggggcaatct gcgcatctag cgtgacttgt gctccttgcg aaatcaccca
     7561 attcatccgg cctaaactgt ccgtcacttg ctgagaaaag agctcaccac cgtcgatatc
     7621 cataccggaa gtaaacacca cgggcgagcg ttgcacctga cccgccaagc gtgacaaatc
     7681 acgcatcacc tgcacacctg agtatgtttc atgactcagc aacaggttca gttggttcgc
     7741 cacttggcgg caatgcgaca gcagcgtctg cgttttgtca acgtgagcac tgaagatcag
     7801 taggttggaa aaatcgccca cagcctgctc tatctgggga tcataaatac cacgatgaaa
     7861 agtcgggaca tttaatcgga aacgatgttc acgcgcacca gtggcgatca cttgcgaaaa
     7921 cagagcaaga aatagctgtg ttaacgtgag atggtgctct ttcgccaacg cctctaacgc
     7981 aacacgctct tgatgggtaa actgatgcgc caagcgctga gtttgtggac gagcttcgtt
     8041 atcctggtgg gacaaatagg gcaagggagg ctcagggggc aatgatgata gacgcgcttg
     8101 ccaccactgt ttatcgctgg ccttgcgctg cgctaaatag cgatccgctt gctgatggtc
     8161 aaggtaatga aaataggtta tctgaggctc ttcgctcatg actaaatcgg attcttgtgc
     8221 agacaggtaa agtcgcgcta actcttcgac cacaattcgg aaactctgcg catcgcacgc
     8281 aatcatatcc gcatcaatgt gcaatcgatg ctcattattg gcgagcaagg tcacactgat
     8341 ctcgatgggg ctgctttgat tcaaatccaa gatttggtgg ctcattcgct ctcgcttgtt
     8401 atgcaagaac tgctcgacct ctggtttgga atagcgcgca atgtcttcca ccgttagttg
     8461 gtgacaagca gatagaggga gaatgtgttg ttgcccctcg gcagtgatcg ctaaccgtaa
     8521 catgggatgc ttcgcataca gtgcccgcac cgccattgat aacgcttcac gatttaaatc
     8581 tcgtccatcg aactcggcat agagatgggc agccaagcct tccatcgcat tgcctttttg
     8641 ccttcctaac caataagcgg cctgcattgc cgtcatttct ttcatgttaa aatccaaaca
     8701 tagtccattc acttcgcctg tcggtctgtc gtctgtcggc gcacaatttg atagcatttc
     8761 gccacccaaa tttacattaa taataatcat tatcatttac atgtaaagta attaaaatgc
     8821 caaacaacga ggcttgtagt gaaagaatgt cagttcatct tgttgatttt actggttagc
     8881 atagggtgac ttgagcaaga tttcggcttg acatatcgat tcctctttct taataattcc
     8941 gacattaacg ataataatta tcattaacat tatttatttt tacaactcag ttaccgatat
     9001 ggctcagggg gaaacatgcc tacgctcagc aaattgattc actccactcc ttgtggaaca
     9061 ctcccttctg tggaagagat cattcaacac gcctcactgg acgaagagag cgaagcgttt
     9121 atccgacaac gtcgccaaga catcactcga attctgaatg gccaagaccc tcgattactg
     9181 gtgatcatcg gcccatgttc aattcacgac ccgcaagcag gcctagaata tgcgcagaaa
     9241 ctggccaaca ttcagcatca gcatgaaaag caacttctga ttgtgatgcg aacttacttt
     9301 gaaaaaccgc gcacacgcgc aggatggaaa gggctgatcg tcgatcccga tctcgataac
     9361 agccacgaca ttaataaagg tctgcggctt gctcgacaat tcttacagca agtcatcaag
     9421 cttggccttg cgacggcaac cgagtattta gacaccacga cttaccccta tatttctgac
     9481 ctcatttgct ggggtgccat tggcgcgagg acaactgaat ctcaaattca ccgtcaaatg
     9541 gcctcggcgc ttccctgtcc tattggtttc aaaaacggga ccgacggcaa tgttgatatt
     9601 gctatcgacg cgatacacgc ggcaaactca ccccatctca tctgtgtgcc aggatttggg
     9661 gcacgtactc tcacagccat cagtcatggt aaccccaatg gccatatcat tttgcgaggt
     9721 ggcaaaacgc caaactacac caccgagcat gtttgccaaa tcagccaaca actggaagcc
     9781 aacgatctta acccgcgcct gatcattgat tgcagccatg gcaatagcct gaaagtggca
     9841 aagaaccaac tcgatgtggc gagaaacatc gcctgtcagt tgatcgaagg agaaaaatgc
     9901 attgcaggcg tgatggcgga gagcttcttg gtagcaggcg cgcaaaagat caccgatcgt
     9961 ccgttggtca aaggcatgtc gattactgat gaatgtttgg ggtgggaaga gacggaaagt
    10021 attctcaata tttttgcgga agcggtgaat gtcgtgatga cggagcgctt ttccaccgtt
    10081 gcctaaatca ccagtgggac tagggactag ggactaggga ctagggacta gggactaggg
    10141 actagcaaac tagaaaacta gaaaactaga aaactagaaa actagcaacc tagcaaccta
    10201 gcaacctagc aacctagcaa cctagcaacc tagcaaccta gcaacctagc aacctagcaa
    10261 gcatatcaaa ggaatggtta ccatccacca ttcctcttct tttgcttcag caagttatta
    10321 attatccaat gtcgcaccac cgtcaactct gagatcgtgc aaggtaatgt gccctgcgtg
    10381 ctcggaaagt aaaaacagta ccgaccgtgc gatgtcttgt ggctcagcca tttttcttaa
    10441 cggaatcccc aaacgaaatt gctctaaatt ccctgcaatg acttgaggtt caccgtattc
    10501 ttccgaccac aattgcatct gcatgtctgt gcgtgttgaa ccggggctga caatattgca
    10561 gcgtactcca tattccgcca actccattcc catcgattta accagcatgt gcaacgccgc
    10621 cttagatgcc ccataagccc ccatatttgg acgaggtgta ttggccgcat tagaaccgac
    10681 aatcaccata ctgcctgagc gtcgtgcttt cattccttct gccaaggcct gcatcaccgc
    10741 caaggtacca aacgtgttca cattgaaagt gtgctcaatt tgcgccagag gcatgctcgt
    10801 aatggagcca agatgcaata cgccggcaca acatacgagg tgatcaaact ggccatgttg
    10861 ttcaatcatt tgcgccacac gacgagcaac agactccggc tgagaaagat ccaagtgata
    10921 gcaaaataac tgctcgcgat agcggttctt caatgcgtca ctgtctgtct tgagtcgcac
    10981 ttcatcgatg tccgtggcga ccactcgagc ccccgcttca agtagatgct gcatcacact
    11041 gaaaccaata cctttcgccg caccagtcag aaaaacagtt tgtttttcaa gaaattggtt
    11101 aaacataaaa acgttatctc tttaatctgt gttcacttat cccgtcatgg atatctgcac
    11161 ccatgctata aattcgtgat ttaatgcaca aaaacaaact tagatattaa tgataattat
    11221 tatcgttagc atttaaatcg tgataactgt aatcttactc cactgaataa gcaacctata
    11281 cccaaccgat gacattgcag gccagacaaa catgccgact cacaaacata acgagtctat
    11341 ggcattgaga tcagtccgtc gccaccaccg caaagttgat tcagttggga aaagagtgca
    11401 ctcctttatc cgcacattgc gccgctaaaa gagcactctt tcgtatacca cgatcgaaat
    11461 atctagaggg atctgttatg aaacgtgaag tgattggcta taccaaaatg gcaaacgaac
    11521 tgttggataa cgaactatca tcgtcgccat ttttcttcgc ttctccaaat aacactatga
    11581 tgggcatcgg cgttcaagaa gagcgtcttc aaaccttgcc attttctgaa ttggctgatg
    11641 tggcgaataa catgctcaaa aatgccaaaa ctagcgaatc agacaatccg gttttgtttg
    11701 gtgttgtgcc atttaatcaa gaaaacatga ctcgatttgt tattccaaag acgttgtaca
    11761 tctccagtag cacccgagct tcgcacacgt ccgcctcctc agcaccacaa gctcgtctta
    11821 tttcttcgcc aagtggccac cactataagc agggggtgca tgatctctta gggatgtttg
    11881 ccaatcagga actctcgaaa gtcgtactgt ctcgtgctat agaagtggcg acagaaaccg
    11941 acattcaaca gcaagcctta ctgagaaact tgctctccat taacgctaaa ggctacacct
    12001 ttgctgcgca aattggcgac aaccaaaagt tgatgggagc cagcccagag ctgcttgtag
    12061 ccaaaaaagg cagccacctg atttccaatc cgctggccgg ttcaagacca cgctcagagt
    12121 ctgagcaaca aaatcaggcg tccattcaat cgctgctcaa tacgggcaag gatctccatg
    12181 aacacggctt ggtggtggaa gaagttgagc gcgtcatgag caagtattgc tgcaatttgt
    12241 acacgccgat ggttccgtcg gtgatcgaga cccaaacgat gctgcatctt tctacacaac
    12301 tcgaaggaca agtgttggat cccgccatca atgtgttgca agtggctgcg gagctgcatc
    12361 ccaccccagc ggtctgtggc taccctcgcg agaaagccta tgaagcgatc aaaagattgg
    12421 aacagtttga tcgcggttat tttaccggca tggttggatg gtgcgattca cgtggaaatg
    12481 gggagtgggt tgtgacgatt cgctgcgcag aagtgcagcc gcgtcggatg aaggtgtttg
    12541 ctggagcggg catcgtcaac gagtcgcaac ctcaaagtga gcttgatgaa acaggggcca
    12601 aaatgaacac catcttaaaa gccgcaggga ttcaactgaa cgaaatgtta acggcataag
    12661 gtatcggcat gaactctgta caatctgatt tcactccatg gccagagcag atggcggacg
    12721 attatcgccg ccttggctta tggcaagata aaacgctcta tcagtatctc aagcaatcca
    12781 ttattcgcta cccgaccaat attgctattg tatgccgtca acaaagcatc acatacgctg
    12841 agcttgagcg aaaaatccat gcggctgcca atgggtttcg ctcgctgggc ctcgctgaag
    12901 gcgataacgt gattctgcag atgaccaata tcgccgagtt ctatgtcagt tactttgcgt
    12961 tgattcatca aggcattcgc ccaatattgg cgttacctgc ccatcgtcac gctgagatta
    13021 gctacttctg ccaacatgcc caagccaaag cgtatctgat cgatggccaa actcgtggtt
    13081 ttgactacca aacgctggcc gaaaaacttc tcaaagagca cccatgtttg cgccatgtca
    13141 tcgtcagagc caatcactcc gagctgctgc aatctcattt catctcattt gacgactttc
    13201 gcgatgaacg agaactggcc cctgtcagta acgcaagtca ggttgccttt tttcaacttt
    13261 ccggcgggac gacgggcact cccaaattga tcccacgtac gcacaatgat tatgcttaca
    13321 gtgtggtcgg cagtaacgcc atctgtggtt ttaatgagta cacacgctat ctttgcgcgc
    13381 tacccgctgc gcacaatttt ccgctcagtt ccccaggttc gcttggagta tttttcgctg
    13441 gtggcaccgt tgtcctgacg caagacccaa cgcccaaagc ggcatttcct ctgattgaac
    13501 gtcacaaagt aaccgtatcg gctctggttc ccccgttagc tttgctgtgg atggatgcgg
    13561 cgccacacgc acgctacaac ttatcgagct tacagttaat ccaagttggt ggtgctaagt
    13621 tgagccaaag tgcggcaaaa gctttgccaa aagcactcaa ttgccagctt caacaagtgt
    13681 tcggcatggc agaagggcta gtgaattata ctcgcctgga cgatccgctg gaggtgatca
    13741 tcgaaacgca aggtcggccc atatccgccc atgatcaagt aaaagtagtc aatgaagccg
    13801 gtgaagaggt tgcctgcgga gaagaaggtt ttctccttac ccaagggcct tatacgattc
    13861 gcggctacta ccgagcaccg gagcacaatc agcgttcgtt cactcacaac ggtttttatc
    13921 gcactggcga tattgtgaag ataacagagc aaggcaatat catcgtcaca ggccgagaca
    13981 aagatcagat caatcgtggc ggtgaaaaaa tcgcggcaga agaagtggag aatcatttgc
    14041 tgggccacag tgcgattcat gatgtggcgc tgattgccat tcccgaccgc ttgttgggtg
    14101 agcgaagctg cgcagtgatc gtcaccaaac gtcatctcaa tatcacagga acggaactaa
    14161 aacgctactt acgcagcaaa gggttagcgg actataagat ccccgatgtg atccaatttg
    14221 ccgatgctct gcccaaaaca tccgtaggaa agatcgacaa gaaacgcttg cgtgaatctt
    14281 acgcccagct tggtttgagt gcttagtagc gaaaagtaag tcgtgaacag aacggaataa
    14341 aaaaacggaa taaaaagaaa gccgatttta atgaaatcgg ctttcttctg tttcgaggcg
    14401 ctatcgatga acaacggcag tggactaata cactgcatcc atcacatcat gacgttcatc
    14461 gtgatacgct tcttccgtct tacctctttt ccagtaagga atcgcgtaga gcttgtcacg
    14521 cgcgatctga tagtcattgc gcaagatctt acggcagttg atcacactct ggttttcacc
    14581 cgcgataaaa gcagacagcg aggtcgcttt ctctggggag ggtagttgct taatcgcctt
    14641 agctaatgcg ggctcggcat catgaggatt gcgcatcaac caattgatgg ccatctcttc
    14701 tggatgaaca agatcgtgga tatcttcaat ctcatccacc tcaataaaca catagccttt
    14761 ggcgtcactg ggcaactttt ccaagatggc actaatcgca ggcaccgccg agagatcacc
    14821 tgcgattata tgccaatccg cgggttcaat gagcgggtca ggtcctgctg gcccaattaa
    14881 accaatctgc gagccgatgt ctgcctttag tgcccaacca ccgcccggag tctcctcccc
    14941 atgcgtcaca aaatcgatgt ccagctcatt caccgccgca cgatattgtc tgaccgagta
    15001 agctctcgga acgggtttgt gttcaggcca aatgacgttg tccccttctc gcaccggcaa
    15061 ctggagaatg ccacttgctt ggttggggaa aaacactttg atgtgcgaac cattttggtc
    15121 ttccgggaag ccgattaaat cctctccggt taacgttact cggagtaagt tttttgagat
    15181 ggtttctttg cgtacaaaat ccagtaacat tggatagacg cgctctgggc tgtcactcat
    15241 tctttcacct aatctttttt gttatttttg cctagctgac gttgttatct ttgaccttca
    15301 cacttaggcg acggccatgg tttgttcttc atttctcgct tgttcaatca ccagccacca
    15361 ctctctaagc gaagccgctt ccatcaattg accaaacgaa atgttctcac cctgttgatg
    15421 ccatttttcc accaacacca tcgcccgcat cgagtccaag ccaacgaaca ttaaatcctc
    15481 atcaagatca acctcgtctg gttgtattcc taagctcgtc gcaacgtcct gctggatctg
    15541 ttccagcgtt agcggctttt gcgaacggat ttcatctaat gcctcatcga gacgctttac
    15601 gctgccacta cgactggcca cgtattccaa ggtccgcaaa tgatcttctc gagtaaaatc
    15661 cgcaatagca tcaccaatca caaacggctg gatgtccagc atgaaggcgt ctaacgtggt
    15721 cgaaagtatg ccgatatggc cataaatccc agaaatgatg agctggcttt tcccttgcgc
    15781 gcgcataaac tcgagcaatg gggttttctt aaatgcgctg taacgccatt tgacgtattc
    15841 aatgtcaccc tcttccgggc tgagcgcttc aacgataggt acatgatcgc cattcaggcc
    15901 cggcccccag aaatcagtga gcagcgctcg gtctgtcgga tgttggttag caggctgcgc
    15961 cgtatagata acgggaatgc ccgctttttt cgctgcggct tttaagcgtt gaatatgttg
    16021 aatgatgtca acaactggcg atgaatctgg ctgataatag ttgacgaaat attcttgcat
    16081 atcgtggatc aaaagtacgg cctggtcggg atcgattgtc cagcccgttc tgttatctgg
    16141 aaactcagcg ggggttggca acggatagcc agcaattttg gggattccca tgttgataat
    16201 cctttcattt tgtttgtcat gatggtggcg gttcgattac gcgccactca cagacgaagc
    16261 atgacggtta gcgtcgtttt tacgagtgat aagctaatct tggctcactg gcgcaaggcc
    16321 tttttggctg cgccaatgct ggatctgctg actgatgtac cattggataa tgttgtcaaa
    16381 aagtgcttcc acatactctt ctgataaccc ctgttcatta gcccaatgcc ggcgttcttc
    16441 cagcatggac gccactcgct caggggcagg tatgcttttc tcatcgggtt taaattgtgc
    16501 ggcagctttc acgtatccca ttctctgaga gaggatatgg acaatctctt tatcaagagt
    16561 gtcgattccc agtcgaatat cattgaggct ttcacacgct tctggtttct tcaacgatgc
    16621 cacggttatt tcctttcgat tgaattcctt gctttatgtg cgtccgcctc gcagcggttg
    16681 gcacagacaa acaggttatt tcagtggttg ttcacttcga aaccacacaa aacataaatg
    16741 agaatgtata tcattaacaa tgattataca accgcacaca accatttctt taccatacgg
    16801 ccacctaccc tcgtcgtgtt tttctttttc gaccaatagg ttgtagaacc atcacggcag
    16861 aatggtgctt aaaatgcgct tcttgtcgat tttacctacg gccgtttttg gcaacgattt
    16921 gaccgcaaac agttcatcag gaagtttgaa tgcggcgatc tctttggttt ggagaaattg
    16981 ccgaatgtct cgcaacataa tttcgggacc tcgaatgacg gcggcgacgg cgattttttc
    17041 acctaaatga gcatctggca ggggaaacac cgctacttgg gcaatttgtg gatgcgacaa
    17101 taagagctct tctaactcat cagcagcaat gttttcgcca gcacgaatga tcacatcctt
    17161 tatccgtcca gtgaccgtga agtaaccgtt ggcatcgacg accacgcgat cgccactgcg
    17221 ataataccct tcatccgtaa acgcccgcag attatgctct ggcgcacggt aatatccgct
    17281 aagcgtgtaa ggccctcggg tcagcagttc cccttcctct ccaatcgcaa ctggcttgcc
    17341 ttgatcatcc acaacgagga cctcgtccca ttcgctgaca ggacgacctt gccttgttgc
    17401 aataatttct ttgtcgtcgc ccaaacgggt acacgcaatc aaaccttccg ccataccaaa
    17461 aacttgctgc aacgcgtttg gaaaggcgtt ttgcatttcc agcgcatcgc tataggcaag
    17521 cttggaacca ccgacttgca tcaaacgcaa actcgaacga tccgtcgact cccattgagt
    17581 tgcctccgtc cacagctgcg ccaatgcagg caccaacgcc gttgcggtaa tacactgttt
    17641 ttcaataagt tcaaaacaat aatctgggct tgggttggtg gtcaaaacca ctttgccgcc
    17701 agcattcaac acccctaaga tcccaggaca gcccaaggta aaattgtgtg ccgcaggcaa
    17761 caccgccaaa tacacatcct gcgcgctgat ttcactggct ttcgcacatt gctcaacatt
    17821 aaacagataa tcattgtgag ttcgggggat aagtttgggt agccctgtcg tgcctccaga
    17881 aacgaggaaa agtgccgggt gttctgggtc taccatcgct ggtgtaaaat cgccagcgtc
    17941 acactctggc aacggcgaaa attgaccaaa atgcccgctg atatagcagc gtatggacac
    18001 tgatagttcc gcttgcaact gagtggcaat cgccaacgct ttgtcatcct tttcatgatt
    18061 ggagccgatg tacacttttg cctcagagag ttgcataaag tggcgaattt cgaccaaacc
    18121 gtgtgcaggt aatgccagta cgggaaccac accaaggcgc tgaagagcaa aaaacacgac
    18181 gagaaaatcg agtgtattgg ctagctgcaa gacaacactg tcaccacaca caagcccttc
    18241 ttctcgcaac ccagcagcga tcctatccac atgattggcc aactcgagat agctcagtga
    18301 agtgtggtta tcggtcaccg ctatcctatc agggtgacgc tctactccct gatgaagaat
    18361 ttgccacagc ggcaaattgc gccacaaatt tgcagcctga tattgttcac gttgaatact
    18421 aggtttacgc acaaagccat cgagtatctg ctttggtgtt tcggttgtcg cgacgaccat
    18481 atctatcctt gcctttcttt aaggtcactc ctatttggat tactggccgt agcactaggc
    18541 atgagtaacc caaaccaata cgcaaatcag tgatattaat aacaccaaat gcaaatggta
    18601 ataataatca tttgaacaga tcaatcaagt aatgatatgg ttaattccta cacttagccg
    18661 caaagaaaat cggcaataag tcacgaaaaa tgaaaggaaa ttattttgtc agaacctcta
    18721 aaagagtttg atttgcttgc cacgctcagc gagttactgc gagtcagcga agctgaaatt
    18781 cagtccgaca ctaacctgat tgaactgggc ctcgactcca tcagtttaat gcgcctcact
    18841 ggtcgccttc gccaagtggg tatcgaagtc aactttgccc aactgatgaa ctcaccaacg
    18901 ttcagctctt ggcaaaccat cattttcaac gcaaaggcac ttgcctaaag caccacggac
    18961 atgggctatt tgttcgaaat agccttttca ataggacaaa aaaatgaaac taaaattaag
    19021 cgttatgttg gtcagcaccc tgatttctgg tggtgcaatg gcgaaagatc ttgtgatcga
    19081 gcattacatg gggagcacta aaatttcaga tgcaccaaag cgtgttgttg ttattggtca
    19141 tggggcctta gacgctctgg attatcttgg catcgagccc gttgccgttg cgaaagcgcc
    19201 aataatgcca caatatctcg ataagtttca ggatgcgaaa tacgcctcgg cgggcagctt
    19261 atttgagcca gattttgaaa ccatctacag ccaaaaacca gacttgatca tcattggtcc
    19321 tcgtgcgacg tccaaataca aagagctatc ggaaattgcc ccgaccatcg tgttcagtgc
    19381 cgatctcaag caaggctact ggcagagcac acaaaaacaa tggcgtaata tgggcgaaat
    19441 tttcaacgcc caacaaaaga ttgagcagaa gattagtcag ctcaatgaag agtttgccgc
    19501 catcaaacaa tacaacgaga aaaaccaagt ggatgcgctc accatcatga catccggcgg
    19561 caatatcacg acgtttggct cgcaatcccg ctttgcttcg gtttacgaag attttggttt
    19621 taaggaaagt tcctctaacg ttaagaccaa caaccacggt gatatcatct cttacgagta
    19681 cattaataaa gccaacccaa gtacgctatt ggtgattgac ggtgataagc tctcaggaaa
    19741 aggcaatcaa gttgaagaac agtatcttga caacgatctg gtcaaagcca ccaacgctta
    19801 caaaaacaaa cgaatcacct tacttgatct agacgcttgg tatctctcaa tctcaggtat
    19861 ttctgcaacg gaaaagatgg tttccgacat caaagagacc gtcgaactgt agtcattctc
    19921 tctagtcgat atagagaaac taattgctat aaaaacgctt ctgatcaaca tcagaggcgt
    19981 tttactttgg gaagggctag aagttcaact gcaatgaagc accaatcata cgtggttgct
    20041 gtgtaagctg atcgttcaag ttgctcgatg tgtacagagt cgttttattg gaatcaaata
    20101 ggttggtggc aaacagagta gctcggccgt tttcaaacac ataagccaat tgagcattag
    20161 cgacccaata tgcatcaatt gttgtgattg ccgtgttgct tctatctgag tagtaatcgc
    20221 ccgtgtaagc cgcgttggca cttaactcaa acccatcaaa gaagctatac tgccctccta
    20281 aattacccgt tatgtttggt gctcgctcta gttctttaga agttccattc acctctttgt
    20341 attctgtttt caataaacct aagttagcaa atagctccaa tgaatctgtg gcataccaac
    20401 gtgtgccgac ctctacacca taggttttag cttcgtctaa attggtaatg aatacatcac
    20461 cattggcaag cagttgggtc atctgcatgt catcaaaatc gttatagaag gtgttggtga
    20521 gtaactctag cgaatgacct aaacgatgac gagtatagaa ctcatagttc cacaggtact
    20581 cttctttaaa ctcgtaaggc ttaaaaccac cagaagtaat actattgaaa cctaagcctg
    20641 cgccacccgc attgtaacct tttgccactt taaaaccgaa ggtctgatca ttagctggct
    20701 tatacgcgat atcgaactta ggtaggaaaa cccctaacgt ctcatcataa tcaatgttga
    20761 atacttcaac ttttcttgtg atatgttcct tctcatagcg ccctgccagc gtaacatcta
    20821 ttgattgcgt gatcgcataa gtcatttctg caaagagaga ctgcgtatcc ttactgcctt
    20881 tcataggatt gctaccgctc gtagtggtaa aggactcatt ctgtttagaa gagtaataac
    20941 gagcaccaaa caatgcgctc agtcgaccgt tacttgaaag gtacttcaaa ataggttcaa
    21001 catggtactc cgagccactg gttgaaaaat caaacttatc cactggatat gtaagccgct
    21061 cgttggtgaa atcggcgtaa accacattac tttcaaaagt aaattgatca ttcagttgcc
    21121 atgaaacatc ccataccgta ctgagcgaac ttgtctcaaa aacagctcga aaagcatttg
    21181 ctccttcaat gttgatgctt tctgactggg gactacgaga gtccataagc gatacaccaa
    21241 gcgttgtttt gaaaccatcc attgatgaag gctcatagag taacttgcct ctcaaagaac
    21301 tcatttcaat acggcttgac tcaccagcag ggtcataggc tgccaagcca acaaaacttt
    21361 ctttcttttg ttggtcaaag ctgaggcgga atgcaagttc gtcttggatg attggtgcag
    21421 agatcattgc agcggtttgt gaatagtttc gctcaccgat acctgctttt actgcacttt
    21481 caaaatggtg ggtagggtcg ttggttttca ttacaatcgc acccgcagaa gagttaccac
    21541 cttgaatata gctttgcgga cctaaataca cttcgacttg ctgcatgtcc caaagagaac
    21601 gcggaccaaa cgcaatttcc gaatacgtca gtgagcggcc atcaatggac atatttaaac
    21661 gaggtgaagt accagcaaag ctcgccagac caccgacaga tgggccagaa ccatcaatac
    21721 cacgcaccgt tggcatgctg ttaccttggc cagagtccac catattggga ataagttgca
    21781 acaggtcatc gatctctgtt gcacctgggg tattgtctat cgtctcctgg tcgaacactt
    21841 ggacactcga actggtgtca taaatggttc tttctgtttt ctcaccgatc acaacgacaa
    21901 caggcatctc ttcttttttg ttgctgttgg tactctcggt ttgagcatag gcttgaccac
    21961 tggcacaaag ccccatcact accgcagaca aagcgtgcag tttaaaggtt tttttttctg
    22021 caacgctcgt tcgcgctggg cgtaaagctg ccatttgaat ttctccttaa ctctaataaa
    22081 caactgattg cattcaggat gcacaggcat agcgagtggt gcttctacct cgagattgag
    22141 tagagaggcg taaagagacc gaaactgaac agcgttgcac tatagagtca cgctcaaaag
    22201 ccatgtgctt gattgcaaat attccgactg acatacgttc caaacggggg ctgattcagg
    22261 ccaaaagcct aaactcaact atcgagtggt ataacaacgt agttcacaac gcattctaat
    22321 tattgataat ttaaatgtaa agcattctca tttgcatttg tgagaatgta tgctactcac
    22381 cgcatgagat gccttcattg tcctgagttc tgttcagcta aggtattgag tgattgatgc
    22441 ataaacacca tcaactgctc actgagatgg gtgatttgct cttgtccaaa ccatcgttgt
    22501 tcgccttcta ccgtgaaggt aatgttggct gcgtccttcc ttacgcgaaa tgtcatattg
    22561 agtccatcgt tggtgccatt cgcgacgacc ttgcgctcac tctgacaccc accaaataca
    22621 atatcctcat caataagcac attgatataa ggggactgac ttgcttttac attgagactg
    22681 ttacttagag ggtgcttacc gtgacgataa agaagacgta actcagccat gagccgcttc
    22741 accctatcca caaagttttc ctcgatatcg gcattgatcc acagcggtaa ggtgttgacc
    22801 atcaaacaag gcgtattggc gcagcggtta cccattcgat ttaaataggg tagccagatc
    22861 cacaatccgt cacttgccga ttgctgctct gtgagaacct gcttttcaac gcagtacaga
    22921 ccgaccaaaa ccaccaacaa atccacccaa gcccactgct gttgttggct gacgtttaag
    22981 agcgccgctc ttagctcagg atcaacctcc tttgcaatgg caaaagtgtc gttattgaag
    23041 tcatcatcgt tgaacgagat aaacgagtgc tgattgatat aatccaacca aaaacgttga
    23101 tctttctctg ctcgctcact acacagataa gcctgctcat ttctgacgta agtattgaat
    23161 cctttaaaga ccacaggaag cgtctggctt tgtatgaatg cagaatagag agaggcacat
    23221 cgttgctcta ttaagtgcaa gctgtagcca tcaagcgcga tgtggtggct tcttatgtac
    23281 caaagtgtct taacctcact gagccgaaaa atggcttgat aggtcataac ctccccagtc
    23341 agatcaattg gcttagcaat atcatcacgg attttctgcc acgcgagttg ttccgcttcg
    23401 gcttcatcaa tcaagttgat gcaatccagc actatcgcag aacagtccag caccacttgg
    23461 cgtggatacc cttgctcatc gcaaccaaaa cagagccgca gcgcttccgc ttcttgtgtg
    23521 gtttccaaaa tagcttgata caaacattcg atatcgcact ctccgctgat ctcgataccg
    23581 tgtgccacat tggaaaaagg tctttcaggg aaagcaatat agtcagccca gtattcttgc
    23641 tgagccaaag agagtgggaa aaacacaggt ttactcattt gcctatcgaa tcgtaataaa
    23701 agatagaaca a
//
