BGC0000461: WAP-8294A2 biosynthetic gene cluster from Lysobacter enzymogenes
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Location: 1 - 63,720 nt. (total: 63,720 nt).
This entry is originally from NCBI GenBank JN596952.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000461
Short description WAP-8294A2 biosynthetic gene cluster from Lysobacter enzymogenes
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: JN596952.1
Compounds
  • WAP-8294A2
Species Lysobacter enzymogenes [taxonomy]
References
Chemical products information
WAP-8294A2
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C73H111N17O21
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AEP18654.1
 466 - 684 (-) MbtH-like protein
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  • AEP18655.1
 784 - 22974 (-) WAPS2
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  • AEP18656.1
 22955 - 50851 (-) WAPS1
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  • AEP18657.1
 50987 - 51958 (-) taurine catabolism dioxygenase
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  • AEP18658.1
 52154 - 53974 (-) efflux transporter
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  • AEP18659.1
 54663 - 56360 (-) pectin lyase fold/virulence factor
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  • AEP18660.1
 57001 - 58227 (+) lytic endopeptidase preproenzyme
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  • AEP18661.1
 58657 - 61752 (+) TonB-dependent receptor
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  • AEP18662.1
 61886 - 62659 (+) SapC-related protein
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  • AEP18663.1
 62643 - 63653 (+) Pass1-related protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
AEP18655.1
Module ?
Specificity: glutamic acid
Evidence for specificity:
Module ?
Specificity: asparagine
Evidence for specificity:
Module ?
Specificity: tryptophan
Evidence for specificity:
Module ?
Specificity: ornithine
Evidence for specificity:
Module ?
Specificity: valine
Evidence for specificity:
AEP18656.1
Module ?
Specificity: serine
Evidence for specificity:
Module ?
Specificity: 3R-hydroxyasparagine / asparagine
Evidence for specificity:
  • Structure-based inference
  • Knock-out studies
Module ?
Specificity: serine
Evidence for specificity:
Module ?
Specificity: glycine
Evidence for specificity:
Module ?
Specificity: phenylalanine
Evidence for specificity:
Module ?
Specificity: leucine
Evidence for specificity:
Module ?
Specificity: ornithine
Evidence for specificity:
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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