BGC0000464: xenoamicin A biosynthetic gene cluster from Xenorhabdus doucetiae
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Location: 2,329,335 - 2,435,321 nt. (total: 105,987 nt).
This entry is originally from NCBI GenBank FO704550.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000464
Short description xenoamicin A biosynthetic gene cluster from Xenorhabdus doucetiae
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP (Cyclic depsipeptide)
Loci NCBI GenBank: FO704550.1
Compounds
  • xenoamicin A
  • xenoamicin B
Species Xenorhabdus doucetiae [taxonomy]
References
Chemical products information
xenoamicin A
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C64H109N13O15
xenoamicin B
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C65H111N13O15
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • XDD1_2270
  • CDG17969.1
 2329335 - 2329775 (-) conserved exported protein of unknown function
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  • XDD1_2271
  • CDG17970.1
 2329772 - 2330617 (-) conserved protein of unknown function
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  • XDD1_2272
  • CDG17971.1
 2330620 - 2330739 (-) protein of unknown function
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  • XDD1_2273
  • CDG17972.1
 2330761 - 2331357 (-) putative haemolysin co-regulated protein (hcp-like)
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  • XDD1_2274
  • CDG17973.1
  • adiC
 2331600 - 2332928 (-) Arginine/agmatine antiporter
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  • XDD1_2275
  • CDG17974.1
  • adiA
 2332946 - 2335219 (-) Biodegradative arginine decarboxylase
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  • XDD1_2276
  • CDG17975.1
 2335560 - 2335682 (+) protein of unknown function
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  • XDD1_2277
  • CDG17976.1
 2335820 - 2336227 (-) conserved protein of unknown function
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  • XDD1_2278
  • CDG17977.1
 2336273 - 2336629 (-) protein of unknown function
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  • XDD1_2279
  • CDG17978.1
  • hol
 2337055 - 2337372 (+) holin
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  • XDD1_2280
  • CDG17979.1
  • V
 2337369 - 2337764 (+) Protein P5
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  • XDD1_2281
  • CDG17980.1
 2338091 - 2360989 (+) Putative Ornithine racemase (fragment)
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  • XDD1_2282
  • CDG17981.1
 2360989 - 2367717 (+) Non-ribosomal peptide synthetase
  • Scaffold biosynthesis
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  • XDD1_2283
  • CDG17982.1
 2367714 - 2382539 (+) Non-ribosomal peptide synthetase
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  • XDD1_2284
  • CDG17983.1
 2382517 - 2384196 (+) Pyridoxal-dependent decarboxylase
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  • XDD1_2285
  • CDG17984.1
 2384422 - 2384577 (-) protein of unknown function
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  • XDD1_2286
  • CDG17985.1
 2384549 - 2406481 (+) Putative Ornithine racemase (fragment)
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  • XDD1_2287
  • CDG17986.1
 2406468 - 2413187 (+) Non-ribosomal peptide synthetase
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  • XDD1_2288
  • CDG17987.1
 2413184 - 2428066 (+) Putative Ornithine racemase (fragment)
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  • XDD1_2289
  • CDG17988.1
 2428102 - 2429754 (+) Pyridoxal-dependent decarboxylase
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  • XDD1_2290
  • CDG17989.1
 2429846 - 2430928 (-) conserved protein of unknown function
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  • XDD1_2291
  • CDG17990.1
  • frmA
 2431366 - 2432475 (+) S-(hydroxymethyl)glutathione dehydrogenase
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  • XDD1_2292
  • CDG17991.1
 2432604 - 2433416 (-) protein of unknown function
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  • XDD1_2293
  • CDG17992.1
 2433648 - 2435321 (+) ABC transporter ATP-binding protein
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NRP-specific information
Subclass Cyclic depsipeptide
Cyclic? yes
NRP-synthases
Gene Modules
XDD1_2281
Module 1
Condensation domain type: Unknown
XDD1_2282
Module 2
Module 3
Condensation domain type: Unknown
Module 4
Condensation domain type: Unknown
Module 5
Condensation domain type: Unknown
Module 6
Condensation domain type: Unknown
Module 7
Condensation domain type: Unknown
XDD1_2283
Module 8
Condensation domain type: Unknown
Module 9
Condensation domain type: Unknown
XDD1_2287
Module 10
Condensation domain type: Unknown
Module 11
Condensation domain type: Unknown
Module 12
Condensation domain type: Unknown
Module 13
Condensation domain type: Unknown
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: SCFYH7235HZBUM2XBV52IUHT, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected NRP module activity
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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