BGC0000468: bottromycin A2 biosynthetic gene cluster from Streptomyces bottropensis
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1,377 - 18,956 nt. (total: 17,580 nt).
This entry is originally from NCBI GenBank HE983629.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000468
Short description bottromycin A2 biosynthetic gene cluster from Streptomyces bottropensis
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • RiPP (Bottromycin)
Loci NCBI GenBank: HE983629.1
Compounds
  • bottromycin A2
Species Streptomyces bottropensis [taxonomy]
References
Chemical products information
bottromycin A2
Copy SMILES
C42H62N8O7S1
Chemical database entries
NPAtlas
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CCM09440.1
  • bmbT
 1377 - 2714 (-)
copy AA seq
copy Nt seq
  • CCM09441.1
  • bmbA
 3168 - 4007 (-)
copy AA seq
copy Nt seq
  • CCM09442.1
  • bmbB
 4435 - 6327 (+)
copy AA seq
copy Nt seq
  • CCM09443.1
  • bmbC
 6474 - 6608 (+)
copy AA seq
copy Nt seq
  • CCM09444.1
  • bmbD
 6672 - 7904 (+)
copy AA seq
copy Nt seq
  • CCM09445.1
  • bmbE
 7792 - 9183 (+)
copy AA seq
copy Nt seq
  • CCM09446.1
  • bmbF
 9180 - 11192 (+)
copy AA seq
copy Nt seq
  • CCM09447.1
  • bmbG
 11227 - 12228 (+)
copy AA seq
copy Nt seq
  • CCM09448.1
  • bmbH
 12231 - 13478 (+)
copy AA seq
copy Nt seq
  • CCM09449.1
  • bmbI
 13468 - 14700 (+)
copy AA seq
copy Nt seq
  • CCM09450.1
  • bmbJ
 14708 - 16741 (+)
copy AA seq
copy Nt seq
  • CCM09451.1
  • bmbR
 16883 - 17437 (+)
copy AA seq
copy Nt seq
  • CCM09452.1
  • bmbK
 17442 - 18956 (+)
copy AA seq
copy Nt seq
RiPP-specific information
Subclass Bottromycin
Cyclic? yes
Peptidases
    bmbG bmbH bmbK bmbK bmbH bmbG
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: RJXZFYIPTBJ27AV3IUUT4BRL, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.