LOCUS       BGC0000469             17668 bp    DNA     linear   BCT 22-JAN-2019
DEFINITION  Streptomyces sp. BC16019 hypothetical protein genes, complete cds;
            bottromycin biosynthetic gene cluster, complete sequence; and
            hypothetical protein genes, complete cds.
ACCESSION   BGC0000469
VERSION     BGC0000469
KEYWORDS    .
SOURCE      Streptomyces sp. BC16019
  ORGANISM  Streptomyces sp. BC16019
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:42:10
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17668
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..1296)
                     /gene="botT"
     CDS             complement(1..1296)
                     /codon_start=1
                     /gene="botT"
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 185.5; E-value: 2.6e-56)"
                     /gene_kind="transport"
                     /product="BotT"
                     /protein_id="AFV25478.1"
                     /transl_table=11
                     /translation="MLPLYLISHGLSLLGNTVASIALPWLVLLRTGDATAVGLVAAASA
                     LPMLLSAVAGGVLIDRVGRRRLSIGADLASAACVAALPVVDGLLGLTVVWFVVLGVAGA
                     VFDVPGMTAREALAPDIAEATGIGMERLAGLRESIAGGVVILAPAAAGGLIMLVDPATV
                     LWLTAGCSALAALVTFALPKTIGAQPTATAQGDGAGLRGDLKRGLGVLRGDRVLTAVTL
                     VSAGSVAVLAPLQNLVLPVHLVGKDSPGGFGVVVSLLAVGGIAGAGLYAAIGTRWSRRT
                     VFVAAQLTSTIGIAGLALLPPVPVMWAAAVLAGAGAGPLPALFLVLVTERIPEEVRGRV
                     LGLQNAVSMTAVPLGTLVAGLTVDWIGLRQTGALLAIAWCVVTLAIVALPALRNLDAGR
                     AKSEPPAEDQPTPDGGSPIPGQGSETADTPTA"
     misc_feature    1..17668
                     /note="bottromycin biosynthetic gene cluster; may include
                     additional flanking genes"
     protocluster    1..17668
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[9864:10746]"
                     /cutoff="20000"
                     /detection_rule="botH"
                     /neighbourhood="10000"
                     /product="bottromycin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9865..10746
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="botH"
                     /neighbourhood="10000"
                     /product="bottromycin"
                     /protocluster_number="1"
     cand_cluster    1..17668
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="botH"
                     /kind="single"
                     /product="bottromycin"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..17668
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000469"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..17668
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="bottromycin"
                     /region_number="1"
                     /rules="botH"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1815..2654)
                     /gene="botOMT"
     CDS             complement(1815..2654)
                     /codon_start=1
                     /gene="botOMT"
                     /product="BotOMT"
                     /protein_id="AFV25479.1"
                     /transl_table=11
                     /translation="MKISLTGAAETLLAPLYARALDARSAHPLLGDHIAAELLDRIDYD
                     FDRLGMGEASAVGVALRARYFDRRVRAFLDAHPESTVVHLGCGLDSRFERLAPGPGVRW
                     FDLDQPDVIELRKQLYPARPGHETLATSVTEPDWPAQVPTDRPVLVVAEGLSMYLSADE
                     GPRMLRTLVAHFPQGELLFDTYSRFAVRSTRSLALFRKTGARLAWGVNDPRELERGIPG
                     LRLIETDSAYATAAGVDVSHLPRTLRRRMRIDTHILARLPVLRHIGHISRYAFGPPA"
     gene            3060..4985
                     /gene="botRMT1"
     CDS             3060..4985
                     /codon_start=1
                     /gene="botRMT1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03975"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bottromycin_Methyltransferase_RRE"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 169.3; E-value: 2.1e-51)"
                     /gene_kind="biosynthetic-additional"
                     /product="BotRMT1"
                     /protein_id="AFV25480.1"
                     /sec_met_domain="TIGR03975 (E-value: 7.5e-160, bitscore:
                     522.8, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="Bottromycin_Methyltransferase_RRE
                     (E-value: 4.5e-41, bitscore: 128.8, seeds: 12, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAAKNVSLVSMPWNSVIRPSIQVGILRSLAESEGWQVDARYSYL
                     DFYGLAQRMLGFSDEKWSEAYELVSEKLYHLSVGDWIFSCRRGDAERREAYFAQLRARR
                     VDDTSIELVDALREVADRHVERTAAELLESAPDVVGFTSMFSQNGPSLAVAERLRDLGY
                     GGVIVLGGSNCEGSMGRALLANYPAVDAIVDGPGEDAFVTLLRQAEAGGPLRTRGRLVT
                     RLPADDDAAPAAPLTAAAALDVPTPNYDGFFEQLHAAGLHGLESEITLPVEFSRGCWWG
                     AKTHCTFCGLNGATMAYRSKNPDTVADELRHLMDRYGVLDFFAVDNILDLKYLDTALPS
                     VEKLNTDHSLFFEVKANMEWADIRAVRRAGVRSVQPGIESLSTEGLRHLRKGATAYQNI
                     RFLLGCAEYGVRADWNILTGYPHETPDSLKAQLDVVASLTHLTPPHITLIRFDRFSPYV
                     EAPESYGLTLTSPLPGYQYAYPRLSPEDLWDIAYHFEGDFTDDPDNGPVRRRLAARVRL
                     WRAHHESARFSYRLGFDSVTLTDERPGLPPHTTTLRGEEARLFRAVVGGTRFRDLQGQE
                     WQGERWDQALETLRTWRRKRWVYIEGTKVIALAVREQPSAYRTPPPKGTPRRARTPVPL
                     TLTARP"
     gene            5082..5216
                     /gene="botA"
     CDS             5082..5216
                     /codon_start=1
                     /gene="botA"
                     /product="BotA"
                     /protein_id="AFV25481.1"
                     /transl_table=11
                     /translation="MGPVVVFDCMTADFLNDDPNNAELSALEMEELESWGAWDGEATS"
     gene            5280..6584
                     /gene="botC"
     CDS             5280..6584
                     /codon_start=1
                     /gene="botC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) YcaO"
                     /gene_kind="biosynthetic-additional"
                     /product="BotC"
                     /protein_id="AFV25482.1"
                     /sec_met_domain="YcaO (E-value: 6.1e-12, bitscore: 35.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEATATECELREVVHRSYPSDRTVTVRCTVRPAEGTAQADGYGT
                     ATTEAVARAKALSEAVERLVACTPFATVARPPTTPAPGSGSGPVPPFPAAGVRTAPDGC
                     ASREYRPLSGDGPRRVPLYWSSPWVAGEELRAGTLSAAEARLSSTVGWAVAPTPEAALR
                     GALLELTELIDYGVFLHRRLAGPARPRSAGDETLVVPLGGAVRTPTVLAVAYGRGRLMP
                     ATGLGCGASRAEATDRALLELAQAETMWRSNPTAEPAERFFLRRFERWPLLTRCATLDF
                     ELSDLSGLDGLSGLDGLSRLDGLSRLDHPSDLNDPAGRPAPYDDGPHPASPLEELEAGG
                     ITVWADSGAVDISGPDIPRTRLCFAHVVSDPQPLLGLVRAGIPVFDTGEVRRTLDPSRR
                     DAHRDTPRGAPRDAARDRSADRGPAGRGRQGRRSA"
     gene            6697..7899
                     /gene="botCD"
     CDS             6697..7899
                     /codon_start=1
                     /gene="botCD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) YcaO"
                     /gene_kind="biosynthetic-additional"
                     /product="BotCD"
                     /protein_id="AFV25483.1"
                     /sec_met_domain="YcaO (E-value: 6.6e-40, bitscore: 127.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLTDAEGALCSRSSGKGLGHRSMASALFESAEHYHLDWRRDPRA
                     SEAEFLPGREIAGQDTARRSALLRRLGGIMPDAPVLTRTYRPVEETLTGRADHGPAGRP
                     HRHPVFLRDGGYRNWPHPDDDRSFQPLWHYTSSAGYAAGATVHEALVHAVNELIERDAW
                     SYQLARSYFGLPGEGPELRVVDHDTLPAELRELTGTVEEVREAPVLIVDITCDTGVPAY
                     VVCDARSREEVRLIGSGASPVRTYALQRALLEYLQVRTMFEHGPVDADTEAGQIATALA
                     RYPRHLAAARFDVGQLPHERRAFDADDGLPAAASPEQLLRHLVDRLRDLGVDVHHRVLT
                     PPGSVTVVDVVAPGLEMFDKARAGYPVLPTGRLGERLRPRKDHERGHGVDHGKDRGGAP
                     R"
     gene            7896..9878
                     /gene="botRMT2"
     CDS             7896..9878
                     /codon_start=1
                     /gene="botRMT2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03975"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bottromycin_Methyltransferase_RRE"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 120.4; E-value: 1.4e-36)"
                     /gene_kind="biosynthetic-additional"
                     /product="BotRMT2"
                     /protein_id="AFV25484.1"
                     /sec_met_domain="TIGR03975 (E-value: 3e-131, bitscore:
                     428.4, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="Bottromycin_Methyltransferase_RRE
                     (E-value: 2e-37, bitscore: 117.1, seeds: 12, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLALVAPPWNSLYRPSIQIATLAALEGTGDGDPITPVYAYLDWF
                     EYAVDALECDPAEFVTVYDTIGEELYGLGVGDWIFGGVLDAHGPGEEADVRDRYAAFLT
                     EHGVAEELVGRVLALRAVAPGFAAGLAGRLVATGAECFGFTTSFSQLMPALAVARAVKD
                     QAPERLVLLGGANCDRPMGQAVMRAYPFVDAVVQGEGEAAVAAVRAARGAGDLAAAPGL
                     VLRHEGGLRVSLPTVQPAESAPVPRYAEYFERLRALPHRELIAPHVALPFQMSRGCWWG
                     EKLQCTFCGENGSGMVYRSKPGEQLTKTLRRLTEEHGVFDTYAVDTILARNDNGLAELA
                     AAEVDITTFFEVKANLGPREVGEMRAAGVTMVQPGIESLSSGALKLLRKGATAFHNLRF
                     LVLCQELGIDAQWNLLSAMPDETAEMLQEQLRLIPFITHLAPPSTVSKVRVDRYSPYFE
                     KPEEFGIALDGPEPKYRFVHAGRTAAERAELAYSFDHVELAGRDDSAMAAEMLALRRRL
                     GARVGLWKKLHDQSRFSFRFGPNMTVLHDGRPHVGTGRHVLRGGDDQLFRCLVHGGRLH
                     QAVGQVAAMTGRPEDEVHARVREWARRGWVHLEGRRGLVLAVRDGMRDELGRAAELREA
                     AAESERAAAESGMAGAGSGRVGAGR"
     gene            9865..10746
                     /gene="botH"
     CDS             9865..10746
                     /codon_start=1
                     /gene="botH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     bottromycin: botH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic"
                     /product="BotH"
                     /protein_id="AFV25485.1"
                     /sec_met_domain="botH (E-value: 6.1e-160, bitscore: 520.0,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.8e-13, bitscore: 39.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.3e-11, bitscore:
                     33.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDGNGTSRRDVFEVFSRDGTPIRGFSRPGPGETVVLVHGVAMDR
                     RIWAESGFLDALPDAHVLALDLRGRGESGRVGTAEGHALRRYVEDVRAVLDRFGRARYS
                     LFGTFFGGRIALQVAAVDTRVARAFSFCAHAEQVEIPEDAVEEEAVAVEGPGGHAYLRD
                     HFTGRGAPPWMVEACARVDPGELGAATRGLLHGSDRRTERGHPDQELVLITADGDADLA
                     PFHAGERRLGAHLWLVDAPTRIKAAGRLAEVGRRVAGVLAEGGHGTGDAPAEARTTGDA
                     PAEARASGTGVV"
     gene            10764..12161
                     /gene="botAH"
     CDS             10764..12161
                     /codon_start=1
                     /gene="botAH"
                     /product="BotAH"
                     /protein_id="AFV25486.1"
                     /transl_table=11
                     /translation="MWRRRRGLLPDGDPLVRALEELAERGRGHRLRAVGLVDPATGRPG
                     PPHDLTVTDGTVTAWTPTPPAADGRAAPYTSYAVPGLVDSHAHVSSAADLVGLLVHGVT
                     GFRQLWGEPAHLYAAGVHRARHAVLPRPWVTAGVVDGPGSRIPQGVTVVDGVRSVRQVI
                     EDALAFGFDGIKVYDDVARPAFEVLVREAERAGLPVVGHIPEAVPLDLAQRTLRSSEHL
                     YGIVPNVFRLPPERRWDALAAALRDHPAPGAVPGHFVCPTLVCWRARSGERRYTRPSRA
                     ALQAVDEGRRRSWQSAARDALRLDAAEAHRRGGLVDGLGRIARALADTGTRLLAGTDCG
                     NPFVLAGPSFHKELAELSRAGLDFGAVLRAATTHAYEAMGRRAGPVPGDPADLVLYRRP
                     PDGDVTALARPDAVLVDGVLLDGTDLDRLWALRLAASGLDPSGWARGTLDPPVTTGRPT
                     KETAHAG"
     gene            12151..13377
                     /gene="botCYP"
     CDS             12151..13377
                     /codon_start=1
                     /gene="botCYP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 231.7; E-value: 2.3e-70)"
                     /gene_kind="biosynthetic-additional"
                     /product="BotCYP"
                     /protein_id="AFV25487.2"
                     /sec_met_domain="p450 (E-value: 9.9e-12, bitscore: 34.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQADREPDRTGREAKRPAEPDHPPQQATCPVDFDFFAAPQTYRDA
                     AAEHAGEHGAFYSDRGFWVLTTYDGIVDAFKDEGTFTVGRVSAAEGAEEERWIPLTVEG
                     REHTAWRQRLGAWFTPQRVRELTPSMRAGARRRIEGFLEKGEVSFNEDFARPYVLENLM
                     TAVGWPPDGFDLLIAINRAMIDSRSAPDPRAAAYGELGLPALERFAREHIARRRAEPAD
                     DLTTASFGWEIDGAEVTDDDRASLLCTLFLAGIDSTVNHLANAVQHLAHHEEDRRRFLA
                     GPEVRPPAVEEFLRANSCMYPGRQAATGGAGGVADRGDTVLLPLALANHDPEVFPEPGR
                     IDFDRTRNPHIAFGTGPHQCLGAAFARAQILVALEEWHALVPDYAPSPEQRTAEPPFLR
                     NSYDLRLVW"
     gene            13385..15430
                     /gene="botRMT3"
     CDS             13385..15430
                     /codon_start=1
                     /gene="botRMT3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03975"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bottromycin_Methyltransferase_RRE"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 158.4; E-value: 4.1e-48)"
                     /gene_kind="biosynthetic-additional"
                     /product="BotRMT3"
                     /protein_id="AFV25488.1"
                     /sec_met_domain="TIGR03975 (E-value: 6.4e-161, bitscore:
                     526.4, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="Bottromycin_Methyltransferase_RRE
                     (E-value: 2.6e-38, bitscore: 119.9, seeds: 12, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTTERTEATGPADVTGTTEPTLATTPTEPATPSVPTRPGRAAL
                     VSMPWNNVRRPSIQVGTLRSVARTEGWRVDSHYAYLSFYGLARTALGMRDAEWSQAYET
                     VSEGLYQLSVGDWIFACRDGGAAAREAYFRMLRTKGVDDATIELVDALREVADRHVERT
                     AAELLESAPDLIGFTSTFSQNGPTLAVAERLRDLGYGGVIVLGGSNCEGSMGRALLANY
                     PAVDAIVDGPGEDAFVALLRQVGAGDPPRSHGRLITRLPALADSAPAGISAGQSLEVPT
                     PDYDGFFEQLHTAGLHTLEPEITLPVEFSRGCWWGAKTHCTFCGLNGATMTYRSKNPDT
                     VADELRHLMDRYGVLDFFAVDNILDLKYLDTALPLVEKLNTDHSLFFEVKANMEWADIQ
                     AARRAGVRSVQPGIESLSTEGLRLLKKGATAFQNIRFLLGCAEFGVLPVWNILTGFPHE
                     TPESMLTQIDLLPSLTHLEPPDNDILAVHFDRFSPYVEHPQDYGLTLTHPLPGYQYAYP
                     RLSPGDLWDLAYHFEGDFTEDPRNTAVRERLATAVHHWRTEHHRARFTYRLGFDSVTLT
                     DHRPGLPAHTTVLRDEDARLFRAIIGGTRFRDLQNQEGRDGQPLEKLHTWQEKRWVYIE
                     GTKVIALPVREKPSAYRTPPRKGTPRRSRTTVPLTLTGPPPPRRPG"
     gene            15595..16149
                     /gene="botR"
     CDS             15595..16149
                     /codon_start=1
                     /gene="botR"
                     /product="BotR"
                     /protein_id="AFV25489.1"
                     /transl_table=11
                     /translation="MTTAPTEDQTRAEDLPPSCRDLIGILAQTDRRDAFAALALGATSV
                     AQVAERAGLRPAAAAVALQKLVDGRIAAYDADARTYRLIDDTFRLAVQAEVRISGRGGG
                     DGAGAYFRKGRLTSIPGKAEVRSRVLAVVADSFEAGVTYSEAKVNAICGQWFDDWVTLR
                     RALVDEDLLRRDESGTQYERV"
     gene            16154..17668
                     /gene="botP"
     CDS             16154..17668
                     /codon_start=1
                     /gene="botP"
                     /product="BotP"
                     /protein_id="AFV25490.1"
                     /transl_table=11
                     /translation="MTRVVAGDVGTDTPDKAGTADTAKAADTADTASRAADVVACGRHT
                     GAAVGAFSRRRGFVARPGQVVAEPSADGRAVVLNVGLGPAGSATAATFRAAAAASVRAV
                     GPARTLRLDLALADGSGVPAAERARAVAEGAVLGLYRYDEYRSARAASPLAEVIVATPE
                     RRAVAEGLAAAEATCLARDLVNCPAGTLTPPAFADRIRELAHTAGLDCAVYEGAGLTEL
                     GLTGLTAVGRGSAEPPRYVELTYDPPDADPALTVGLVGKGVTFDSGGLSLKPSGERHAM
                     KADMGGAAAVVAALTALPRLGLPLRVRGHLPLAENMPDGGALRVGDVVRHLDGTTTEIT
                     HTDNEGRVVLADVLVRASRPGPHRSDLVVDVATLTSAAVHALGTRTGALFTPDDRLAQT
                     VLAASERAGESFCRLPLLAHERRNLRSAVADRVNCSHRHGDTIQAALFLQDFVAAGVPW
                     AHLDIAAPAYNDEGPYAEVPYGGTGFAVRTLIETLRALSEGSPDVP"
ORIGIN
        1 tcaggccgtc ggggtatccg ctgtttccga gccctggccc gggatggggg atcctccgtc
       61 gggggtcggc tgatcctctg cggggggttc ggacttggcg cggcccgcgt cgaggttgcg
      121 gagtgccggc agagccacga tcgcgagggt gaccacgcac caggcgatgg cgaggagtgc
      181 gccggtctgg cggaggccga tccagtcgac ggtgagaccg gcgacgaggg tgcccagcgg
      241 gacggcggtc atcgatacgg cgttctggag tccgaggacg cggccgcgca cctcctcggg
      301 gatccgttcg gtgacgagga ccaggaagag ggcgggcagc gggcccgcgc cggcgccggc
      361 caggacggcg gccgcccaca tgacgggcac cggaggcagg agcgcgagcc ccgcgatacc
      421 gatcgtggag gtgagctggg cagccacgaa gacggtacgg cgtgaccagc gggtgccgat
      481 cgcggcgtac aggcctgcgc cggcgatgcc gccgacggcg aggagggaga ccacgacgcc
      541 gaaaccgccg ggtgagtcct tgcccacgag gtggaccggg agcaccaggt tctggagcgg
      601 ggcgaggacg gcgacgctgc cggccgagac cagggtgacg gcggtgagga cgcggtcgcc
      661 gcgcaggacg ccgagtccgc gcttgaggtc gcctcgcagt ccggcgccgt cgccctgggc
      721 cgtggcggtg ggctgggcgc cgatggtctt cgggagggcg aaggtgacga gcgcggcgag
      781 ggccgagcag ccggcggtga gccagaggac ggtcgccggg tcgacgagca tgatgagtcc
      841 gccggcggcg gccggggcga ggatcacgac gccgccggcg atgctctcgc ggagtccggc
      901 gaggcgttcc atgccgatgc cggtggcttc ggcgatgtcc ggtgcgaggg cctcccgggc
      961 ggtcatgccg ggtacgtcga agacggcgcc ggcgacgccg aggacgacga accagacgac
     1021 ggtgaggccg aggaggccgt cgacgacggg gagtgcggcg acgcaggcgg cggaggcgag
     1081 gtccgcgccg atggagaggc ggcggcggcc gacccggtcg atgagcacgc cgccggcgac
     1141 ggccgacagg agcatcggca gggcgctcgc ggcggcgacg aggccgaccg cggtggcgtc
     1201 accggtgcgc agcagcacca gccagggcag ggcgatcgag gccacggtgt tgcccagcag
     1261 ggacaggccg tgggagatga ggtagagcgg cagcatcggg gcattctggt cgtgggccga
     1321 tggcccgtcg gatggttgac cggcgtcacc gccgggtggc cgggggtccc cggcagtccg
     1381 ggtctcccag cgaccggggt cccgcgtggc gtgggccccc gggttgccga ggcttcccca
     1441 aatagccggg gtctaccggc agtcggggtt ccctcgccca gcggtcgggt tcccgggtgt
     1501 tccgggcccc cggctgccga ggcttcccag ctgacggcca tcgaggtcga gcggctcccg
     1561 gaggccctgc gggacttccg ggacactccg aactccctcg gcggccgagg tttcccaaca
     1621 gtcgggcttc ccaggcagcc agggctcccc atctgtcgag ccttcccgag aggccgggac
     1681 ccccaagagg ccgggacccc cgagtaaccg ggacccccgg ctggccggag gctcccggct
     1741 ggccggaggc tcccggtcgg tcggaggctc ccggtcggtc ggaggctccc ggtcggtcgg
     1801 aggctccggc gggatcaggc aggtgggccg aacgcatagc gggagatgtg gccgatgtgg
     1861 cgtagtaccg ggagcctggc gaggatgtgg gtgtcgatgc gcatccggcg ccgcagtgtg
     1921 cggggcaggt ggctcacgtc gacgcccgcc gccgtggcgt acgcgctgtc ggtctcgatc
     1981 agccgcaatc cgggtatccc gcgctccagt tcgcgtgggt cgttcacgcc ccacgcgagc
     2041 cgggcacccg tcttgcggaa gagggccagg gagcgggtgg accgtacggc gaaccgggag
     2101 tacgtgtcga acagcagctc gccctgcggg aagtgggcga cgagggtgcg cagcatgcgg
     2161 ggcccctcgt cggcggagag gtacatgctg aggccctcgg cgaccacgag gacggggcgg
     2221 tcggtgggga cctgggccgg ccagtccggt tcggtgacgg acgtggcgag ggtctcgtgg
     2281 ccggggcggg cggggtagag ctgtttgcgc agttcgatga cgtcgggctg gtcgaggtcg
     2341 aaccagcgca cccccgggcc gggggcgaga cgttcgaacc tgctgtcgag gccgcagccg
     2401 aggtggacca cggtggactc ggggtgcgcg tcgaggaatg cgcggacccg ccggtcgaaa
     2461 tagcgggcgc gcagggccac gccgacggcg gaggcctctc ccatgccgag tcggtcgaag
     2521 tcgtagtcga tgcggtccag cagttcggcc gcgatgtggt cgcccagcag ggggtgggcg
     2581 gagcgggcgt cgagcgcgcg ggcgtagagg ggtgcgagca gggtctccgc cgcgccggtc
     2641 agggaaatct tcacgcgact tctcgcctct ctggcgcaca gaaatagggt cggcgggaaa
     2701 tattgattcg gcgagcgcag ggtaaagccc tcggcaggga ttttccgacc gacagggaca
     2761 gctggcgtcg actcccggcg cgtcatgaca cagcatacgc aaggagcacc atacaccgta
     2821 caacccgacc ggtctcactg tccaccacgc accccacctg cgtatatgcg tacgacctgc
     2881 acaccttccc cgtcgatcac ggagttgatc acaaatacgt ggccgcgcat tgtcgagcag
     2941 tgcatgccgg acgaatgttt ccagccaacc tataccgatg ctttgggcac tgttgactcg
     3001 cgtaattggc ccttctacgg tgattcgagt tgccgcaacc ggctccgggg gttgttttcg
     3061 tgcctgccgc caaaaacgtt tctcttgtat caatgccttg gaacagcgtc atccggcctt
     3121 cgattcaggt cggtattctg cgctcgctcg ccgagagtga aggctggcaa gtagacgccc
     3181 gatattccta tctggatttc tacgggctgg cccagagaat gctggggttc tccgacgaga
     3241 agtggtcgga ggcctatgag ctggtctccg aaaagctcta ccacctttcg gtgggcgact
     3301 ggatcttctc gtgccgccgg ggtgatgccg agcggcggga ggcgtacttc gcccagttgc
     3361 gggcgaggcg ggtcgacgac acgtcgatcg agctggtcga cgcgttgcgc gaggtggcgg
     3421 accggcatgt ggagcggacg gccgccgagc tgctggagtc cgcgccggac gtcgtcggct
     3481 tcacctcgat gttcagccag aacggcccgt cgctggcggt cgcggagcgc ctgcgggacc
     3541 tcggctacgg cggcgtgatc gtgctcggcg gcagcaactg cgagggctcg atgggcaggg
     3601 cgctgctcgc caactacccg gcggtggacg ccatcgtgga cggccccggc gaggacgcct
     3661 tcgtgaccct gctccgccag gccgaggccg gcggcccgct ccgtacgcga ggacgcctgg
     3721 tcacccgcct gcccgccgac gacgacgccg cgccggccgc cccgctcacc gccgctgccg
     3781 ccctggacgt acccaccccc aactacgacg gtttcttcga gcagttgcac gccgccggtc
     3841 tgcacggcct cgaatccgag atcacccttc cggtggagtt ctcccgcggc tgctggtggg
     3901 gcgccaagac ccactgcacc ttctgcggcc tcaacggcgc gaccatggcg taccggagca
     3961 agaaccccga caccgtcgcc gacgagctgc ggcatctgat ggaccgctac ggggtgctcg
     4021 acttcttcgc ggtggacaac atcctcgacc tcaagtacct cgacacggca ctgccgtcgg
     4081 tggagaagct caacaccgac cactcgctgt tcttcgaggt caaggccaac atggagtggg
     4141 ccgacatccg ggccgtgcgc cgggcggggg tccgttccgt gcagccgggg atcgagagcc
     4201 tcagcacgga ggggctgcgg catctcagga agggtgccac ggcgtaccag aacatccggt
     4261 tcctgctggg ctgcgccgag tacggcgtgc gggcggactg gaacatcctc accgggtatc
     4321 cgcacgagac gccggactcc ctcaaggcgc agctggacgt cgtcgcgtcg ctgacgcatc
     4381 tgacgccgcc gcacatcaca ctgatccgct tcgaccggtt cagcccgtac gtcgaggcgc
     4441 ccgagagcta cgggctcacg ctgaccagcc cgctgccggg ctaccagtac gcctatcccc
     4501 gcctctctcc ggaggatctg tgggacatcg cgtaccactt cgagggtgac ttcacggacg
     4561 accccgacaa cgggcccgtg cggcggcggc tcgccgcgcg cgtccggctg tggcgggcgc
     4621 accacgagtc cgcccgcttc agctaccggc tcggtttcga ctcggtcacc ctcaccgacg
     4681 aacgacccgg gctgccgccg cacaccacca ccctgcgggg cgaggaggcg cggctgttcc
     4741 gcgccgtcgt gggcggcacc cggttccgcg acctccaagg gcaggagtgg cagggggaac
     4801 gctgggacca ggccctggaa acgctgcgca cctggcggcg aaagcggtgg gtctacatcg
     4861 aaggcacgaa ggtcatcgca ctggcggtac gcgagcagcc ctcggcctac cgcaccccac
     4921 cgcccaaggg cactccccgg cgggctcgta cccccgtacc cctcacgctc accgctcgac
     4981 cgtaaggagg ccgcccatcg cgcggatgcg ggccgccgcg taccccatga ggcacggaac
     5041 cgaaatcgaa cggcaagcca gaccgacgaa aggatcgaga tatgggaccc gtagtcgtat
     5101 tcgactgcat gaccgcggat ttcctcaacg acgaccccaa caacgccgaa ctgagcgctc
     5161 tggagatgga ggagctggag tcctggggtg cctgggacgg cgaagccacc tcttgagcgc
     5221 cggccggtga gtagccggcg ggtgtgaagt cggcgagacg gaccaccggg agagggagca
     5281 tgctcgaagc gacggcgacg gagtgtgagc tgcgcgaggt cgtccaccgt tcgtatccgt
     5341 cggatcgaac ggtgaccgtg cggtgcaccg tacgccccgc cgagggcacc gcccaggccg
     5401 acggctacgg caccgccacg accgaggccg tggcacgggc gaaggccctg tcggaagccg
     5461 tggagcggct ggtggcgtgc acccccttcg caacggtcgc ccgtccgccg acgaccccgg
     5521 cccccggctc gggctccggt ccggtcccgc ccttcccggc ggccggggta cggaccgcgc
     5581 cggacggctg tgcgagccgg gagtaccggc cgctgtccgg ggacgggccg cgccgggtgc
     5641 cgctgtactg gtcctcgccc tgggtcgccg gcgaggagtt gcgcgcgggc acgctgtcgg
     5701 ccgcggaggc gcggctgtcg agcacggtcg gctgggccgt cgccccgacg ccggaggcgg
     5761 ccctgcgcgg ggcgctgctg gagctgacgg aactgatcga ctacggggtc ttcctgcacc
     5821 gtcgcctggc gggcccggcg cggccccggt cggcgggtga cgagacgctg gtggtgccgc
     5881 tgggcggcgc cgtccgtacg ccgaccgtgc tcgccgtggc gtacggccgc gggcggctga
     5941 tgccggccac cgggctgggc tgcggggcga gtcgggccga ggcgaccgac cgggcgctgc
     6001 tggagctcgc gcaggccgag acgatgtggc ggtcgaaccc caccgccgag ccggccgagc
     6061 gtttctttct gcgccgcttc gagcggtggc cgctgctcac ccggtgcgcg accttggact
     6121 tcgagctcag cgatctgagt ggtctcgacg gtctgagcgg tctcgacggt ctgagtcgtc
     6181 tcgacggtct gagtcgtctc gaccatccga gtgatctgaa cgatccggcc ggccgcccgg
     6241 cgccgtacga cgacgggcca cacccggcgt cccccctgga agagctggag gccggcggca
     6301 tcaccgtgtg ggccgactcc ggtgccgtcg acatctcagg cccggacatc cccaggaccc
     6361 gtctctgctt cgcccatgtg gtgtcggatc cgcagcccct cctgggcctt gtccgcgcag
     6421 gcatccccgt gttcgacacg ggagaagtga ggaggaccct tgacccgtcc cgccgagacg
     6481 cccaccgaga cacaccccga ggcgcacccc gagacgcagc ccgagaccga tctgctgacc
     6541 gcggccctgc tggacggggc cgccaaggac gacgttccgc ctgagcgcga gacggccatc
     6601 cagcaggccc tgtcctccgt cggggactgg ctggccgcgg agcggctgac ggccgacatc
     6661 cgcaagtacg gcatcgagtc cgcgccgacc tacgaggtgc ggctgacgga cgccgagggc
     6721 gcgctctgtt cccgcagctc cggcaagggg ctggggcacc ggagcatggc gagcgcgctg
     6781 ttcgagagcg ccgagcacta ccacctggac tggcgccggg atccgcgggc gtcggaggcg
     6841 gagttcctgc cgggccggga gatcgcgggc caggacaccg cccggcggtc cgcgctgctg
     6901 cgccggctcg gcggcatcat gccggacgcg cccgtgctga cccgtacgta ccgcccggtg
     6961 gaggagaccc tgaccgggcg ggcggaccac ggcccggccg ggcggccgca ccggcacccc
     7021 gtgttcctgc gtgacggcgg ctaccgcaac tggccccacc cggacgacga ccggtcgttc
     7081 cagccgctgt ggcactacac ctccagcgcc gggtacgcgg cgggcgccac cgtgcacgag
     7141 gcgctggtgc acgccgtcaa cgagctgatc gagcgggacg cctggtcgta ccagctggcc
     7201 cggtcgtact tcgggctgcc cggcgagggg cccgagctgc gggtggtcga ccacgacacg
     7261 ctgcccgccg aactgcggga gctgacgggc acggtcgagg aggtccgcga ggcgccggtg
     7321 ctgatcgtcg acatcacctg tgacaccggc gtaccggcct atgtggtgtg cgacgcgcgg
     7381 agccgggagg aggtgcggct gatcggcagc ggggcctcgc cggtgcggac gtacgcgttg
     7441 cagcgggccc tgctcgaata cctccaggtg cgcacgatgt tcgagcacgg gccggtggac
     7501 gcggacaccg aggccgggca gatcgccacc gcgctggccc gctatccccg ccatctcgcc
     7561 gccgcccggt tcgacgtcgg tcaactgccg cacgagcggc gggcgttcga cgcggacgac
     7621 gggctgcccg cggccgcgag ccccgagcag ctgctgcggc atctcgtgga ccggctgcgg
     7681 gacctgggcg tggacgtcca ccaccgggtg ctcacgccgc cggggtccgt cacggtcgtc
     7741 gacgtcgtcg cgccgggcct ggagatgttc gacaaggcgc gggcgggcta tccggtgctg
     7801 ccgaccgggc ggctcggcga gcggctgcga ccgcgcaagg accatgaaag gggccacgga
     7861 gtggaccacg gaaaggaccg cggaggtgcg ccccggtgaa gctcgcgctc gtggcaccac
     7921 cctggaacag cctgtaccgc ccgtccatcc agatcgccac cctcgcggcg ctggagggca
     7981 cgggggacgg tgatccgatc acaccggtgt acgcgtacct ggactggttc gagtacgccg
     8041 tcgacgcgct ggagtgcgat ccggcggagt tcgtcaccgt ctacgacacg atcggcgagg
     8101 agctgtacgg gctcggggtc ggggactgga tcttcggcgg ggtcctggac gcccatggtc
     8161 ccggggagga ggcggacgtc cgcgaccggt acgccgcctt cctcaccgag cacggtgtgg
     8221 ccgaggagct ggtgggccgg gtgctggcgc tgcgcgcggt ggcgcccggg ttcgcggcgg
     8281 ggctcgccgg gcggctcgtg gcgaccggcg cggagtgctt cgggttcacc acgtcgttca
     8341 gtcagctgat gcccgcgctg gccgtcgccc gggccgtcaa ggaccaggcg cccgagcggc
     8401 tggtgctgct cggcggggcg aactgcgacc ggcccatggg gcaggccgtg atgcgggcgt
     8461 acccgttcgt cgacgcggtc gtgcagggcg agggcgaggc ggcggtggcg gcggtccggg
     8521 ccgcgcgcgg cgccggcgac ctcgcggcgg ccccgggcct ggtcctgcgg cacgagggcg
     8581 ggctgcgggt gtcgctgccg acggtgcagc cggccgagtc ggcgccggtg ccccggtacg
     8641 cggagtactt cgaacggctg cgggcgctgc cgcaccgtga gctgatcgcc ccgcatgtgg
     8701 cgctcccgtt ccagatgtcg cggggctgct ggtggggcga gaagctgcag tgcaccttct
     8761 gcggggagaa cggcagcggg atggtctacc gcagcaagcc gggcgagcag ctgaccaaga
     8821 ccctgcgccg gctgaccgag gagcacggcg tgttcgacac gtacgcggtc gacacgatcc
     8881 tcgcgaggaa cgacaacggc ctcgccgaac tcgccgcggc ggaggtcgac atcaccacgt
     8941 tcttcgaggt gaaggccaat ctggggccgc gtgaggtggg cgagatgcgg gcggcgggcg
     9001 tcaccatggt gcagccgggc atcgagagcc tgagcagcgg tgcgctgaag ctgctgcgca
     9061 agggggcgac ggccttccac aacctgcgtt tcctggtgct gtgccaggag ctgggcatcg
     9121 acgcccagtg gaacctgctg tcggcgatgc ccgacgagac ggcggagatg cttcaggagc
     9181 agctgcggct gatcccgttc atcacgcatc tcgcgccgcc gtcgacggtg agcaaggtcc
     9241 gggtcgaccg ctacagcccg tacttcgaga agcccgagga gttcggtatc gcgctggacg
     9301 ggcccgagcc gaagtaccgc ttcgtgcacg ccggccgcac cgccgccgaa cgcgccgagc
     9361 tggcctactc gttcgaccat gtggagctgg cggggcggga cgactcggcc atggccgcgg
     9421 agatgctggc gctgcggcgg cgcctcgggg cccgggtggg cctgtggaag aagctgcacg
     9481 atcagtcgcg gttctcgttc cggttcgggc cgaacatgac cgtgctgcac gacggccggc
     9541 cgcatgtcgg caccgggcgg catgtgctgc ggggcggcga cgaccagctg ttccgctgtc
     9601 tggtgcacgg cggacggctg caccaggccg tcggccaggt cgccgcgatg acgggccggc
     9661 cggaggacga ggtgcacgcg agggtacggg agtgggcgcg gcgcggctgg gtccatctgg
     9721 agggccggcg gggtctcgtc ctcgcggtgc gcgacggcat gcgggacgag ctgggccggg
     9781 cggcggagct gcgggaggcc gcggccgagt cggagcgtgc cgccgccgag tcggggatgg
     9841 ccggtgcggg atcggggagg gtcggtgcgg gacggtaacg gcacgagccg tagggacgtc
     9901 ttcgaggtgt tctcccgcga cggcacgccg atccggggct tcagcaggcc cgggccgggc
     9961 gagaccgtcg tcctcgtcca cggtgtggcc atggaccggc ggatctgggc ggagtcgggg
    10021 ttcctcgacg cgctcccgga cgcccatgtc ctcgcgctcg acctgcgggg acgcggggag
    10081 agcgggcgcg tcggcacggc ggagggccac gccctgcgcc ggtacgtcga ggacgtccgc
    10141 gcggtcctgg accggttcgg ccgcgcacgg tacagcctgt tcggcacgtt cttcggcggg
    10201 cggatcgccc tccaggtcgc cgccgtggac acccgggtgg cccgggcgtt ctccttctgc
    10261 gcgcacgccg agcaggtgga gatccccgag gacgccgtcg aggaggaggc ggtggccgtc
    10321 gagggccccg gcgggcacgc ctatctgcgc gaccacttca ccgggcgggg cgccccgccg
    10381 tggatggtcg aggcctgcgc acgcgtcgac cccggtgagc tgggggcggc cacgcggggt
    10441 ctgctgcacg gctccgaccg gcggaccgaa cgcggccacc ccgaccagga gttggtactg
    10501 atcaccgccg acggcgacgc cgacctggcc cccttccacg ccggggagcg ccgcctcggc
    10561 gcccacctgt ggctcgtcga cgccccgacc cgcatcaagg ccgcggggcg tctcgcggag
    10621 gtcgggcgga gggtggcggg cgtactggcg gagggtgggc acgggacggg agacgcaccg
    10681 gccgaggccc gtacgaccgg agacgcaccg gccgaggccc gcgcgtccgg gacgggggtc
    10741 gtatgacggc gaccgaggac accatgtggc gtcggcgacg ggggctgctg cccgacgggg
    10801 acccgctggt gcgggccctg gaggagctgg cggagcgcgg gcgcgggcat cggctgcggg
    10861 ccgtcgggct cgtcgacccc gccaccgggc ggcccggtcc cccgcacgat ctgacggtga
    10921 ccgacggcac ggtcaccgcc tggaccccga cgccgcccgc cgccgacggg cgcgcggcgc
    10981 cgtacacctc gtacgccgtg ccgggcctcg tcgactccca cgcgcatgtc tcgtccgccg
    11041 ccgacctggt cggtctcctc gtccacggtg tcaccggctt ccggcagctg tggggcgagc
    11101 cggcgcatct gtacgccgcc ggggtgcacc gcgcccggca cgccgtcctg ccccggccct
    11161 gggtcaccgc cggggtggtc gacgggcccg ggtcgcggat cccgcagggg gtcaccgtgg
    11221 tggacggggt ccggtcggtc cggcaggtga tcgaggacgc gctggcgttc ggtttcgacg
    11281 ggatcaaggt gtacgacgac gtcgcgcgcc cggcgttcga ggttctggtc cgggaggccg
    11341 agcgggccgg tctgccggtc gtgggccaca tccccgaggc ggtgcccctg gacctggccc
    11401 agcgcacgtt gcggtcgtcc gagcatctgt acggcatcgt gcccaatgtg ttccggctgc
    11461 cgcccgagcg gcgctgggac gcgctggcgg cggccctgcg cgaccacccg gcacccgggg
    11521 ccgtacccgg ccacttcgtc tgccccaccc tcgtctgctg gcgggcccgc agcggtgagc
    11581 gccggtacac ccgcccctcc cgcgcggccc tccaggcggt ggacgagggc cgccgccggt
    11641 cctggcagtc ggcggcccgg gacgccctcc ggctggacgc cgccgaggcg caccggcgcg
    11701 gcggcctcgt cgacgggctg ggccggatcg cccgcgccct cgccgacacg ggcacccggc
    11761 tgctggcggg caccgactgc ggcaacccgt tcgtcctcgc cggcccctcc ttccacaagg
    11821 agctggccga actgtcccgc gcggggctcg acttcggcgc cgtactgcgg gcggcgacca
    11881 ctcacgcgta cgaggccatg gggcggcggg cgggcccggt gcccggtgat ccggcggacc
    11941 tggtcctcta ccggcggccg cccgacggcg acgtgaccgc cctcgcccgg cccgacgcgg
    12001 tgctcgtcga cggagtcctg ctcgacggca ccgacctcga ccgcctgtgg gcgctacgcc
    12061 tggccgcgtc cggcctcgac ccgtccggct gggcccgcgg caccctcgac ccaccggtca
    12121 ccaccggccg acccacgaag gagacagccc atgcaggctg accgggaacc cgaccgcacg
    12181 gggcgggagg cgaaacgccc cgcagaaccc gaccaccccc cacagcaggc cacatgcccc
    12241 gtcgacttcg acttcttcgc cgcgccgcag acgtatcgcg acgccgccgc cgaacacgcc
    12301 ggtgagcacg gcgccttcta cagcgaccgg ggcttctggg tgctgacgac gtacgacggg
    12361 atcgtggacg cgttcaagga cgagggcacc ttcaccgtcg ggcgggtcag cgcggcggag
    12421 ggcgccgagg aggagcgctg gatcccgctg accgtcgagg gccgcgagca cacggcgtgg
    12481 cggcagcgac tgggtgcctg gttcaccccg cagcgggtgc gggagctgac cccgtcgatg
    12541 cgtgcgggtg cccggcggcg gatcgagggg ttcctggaga agggcgaggt gtcgttcaac
    12601 gaggacttcg cccggccgta cgtcctggag aacctgatga cggccgtggg ctggcccccg
    12661 gacgggttcg acctgctcat cgccatcaac cgggcgatga tcgactcccg ttcggcaccg
    12721 gaccccaggg cggcggcgta cggcgaactc gggcttccgg cgctggagcg gttcgcccgg
    12781 gaacacattg cccggcggcg cgcggagccc gccgacgacc tgaccaccgc cagcttcggc
    12841 tgggagatcg acggtgccga ggtcaccgac gacgaccgtg cctccctgct gtgcacgctg
    12901 ttcctggccg gcatcgactc gacggtgaac catctggcca acgccgtcca gcacctcgcc
    12961 caccacgagg aggaccggcg gcggttcctc gccgggcccg aggtccggcc gccggcggtc
    13021 gaggagttcc tgcgggccaa ctcgtgcatg tacccgggcc ggcaggccgc gaccggcggc
    13081 gcgggcgggg tcgcggaccg gggcgacacc gtgctgcttc cgctcgccct cgccaaccac
    13141 gaccccgagg tgttcccgga gcccggccgg atcgacttcg accggacgcg gaacccgcac
    13201 atcgccttcg gcaccggccc ccaccagtgc ctcggcgcgg ccttcgcgcg cgcccagatc
    13261 ctggtggccc tggaggagtg gcacgccctc gtcccggact acgcgccgtc ccccgagcag
    13321 cgcacggccg aaccaccgtt cctgcgcaac tcctacgacc tgaggctcgt ctggtgaggg
    13381 cgccatgacc ggaacgaccg agaggaccga ggcgaccggc ccggccgatg tgaccggcac
    13441 gaccgagccg accttggcca ccactccgac agaacccgcc accccgtcag tgcccacccg
    13501 accaggccgg gccgccctcg tctccatgcc ctggaacaac gtccgccgcc cctccatcca
    13561 ggtcggcacc ctgcgctccg tcgcccgcac cgaggggtgg cgggtcgact cgcactacgc
    13621 ctacctctcc ttctacggcc tcgcccgcac ggccctcggc atgcgggacg ccgagtggtc
    13681 gcaggcgtac gagacggtgt ccgaggggct gtaccagctc tccgtcgggg actggatctt
    13741 cgcgtgccgc gacggcgggg cggcggcgcg cgaggcgtac ttccggatgc tgcgcaccaa
    13801 gggcgtcgac gacgcgacga tcgagctggt cgacgcgctg cgcgaggtgg ccgaccgcca
    13861 tgtggagcgg acggccgccg agctgctgga atcagccccc gatctcatcg gattcaccag
    13921 caccttcagc cagaacggcc cgacgctggc cgtggccgag cgcctgcggg acctcggcta
    13981 cggcggcgtg atcgtgctcg gcggcagcaa ctgcgagggc tcgatgggcc gcgccctgct
    14041 cgccaactac ccggcggtgg acgccatcgt ggacggcccc ggcgaggacg ccttcgtcgc
    14101 cctgctccgc caggtcgggg ccggcgaccc gccgcgctcc cacggccggc tgatcacccg
    14161 gctgcccgcc ctcgccgaca gcgccccggc cggcatctcc gccggtcagt cgctggaggt
    14221 gcccaccccc gactacgacg gtttcttcga gcagttgcac accgccggcc tgcacaccct
    14281 cgaaccggag atcacccttc cggtggagtt ctcccgcggc tgctggtggg gcgcgaaaac
    14341 ccactgcacc ttctgcggcc tcaacggcgc gaccatgacg taccgcagca agaaccccga
    14401 caccgtcgcc gacgaactcc gccacctcat ggaccgctac ggcgtcctcg acttcttcgc
    14461 cgtcgacaac atcctcgacc tcaaatacct cgacacggca ctcccgctgg tcgaaaagct
    14521 caacaccgac cattccctgt tcttcgaggt caaggccaac atggaatggg ccgacatcca
    14581 ggccgcccgt cgcgccggag tccgctcggt ccagccggga atcgaaagtc tcagcaccga
    14641 ggggctacga ctgctgaaga aaggcgcgac cgccttccag aacatccgtt tcctgctcgg
    14701 ctgcgcggaa ttcggtgtcc tgccggtgtg gaacatcctc accggatttc cccacgaaac
    14761 cccggagtcg atgctcaccc agatcgatct gctgccttcc ctgacccatc tggaaccacc
    14821 cgacaacgac atcctcgccg tgcacttcga ccggttcagc ccgtacgtgg aacacccgca
    14881 ggactacggt ctcaccctga cccacccgct gcccggctac cagtacgcct atccccgtct
    14941 ctcccccggc gacctgtggg acctcgccta ccacttcgag ggcgacttca ccgaggaccc
    15001 ccgcaacacc gccgtccgcg aacgcctcgc cacggccgtc caccactggc gcaccgagca
    15061 ccaccgggcc cgtttcacct accgcctcgg cttcgactcc gtcaccctca ccgaccaccg
    15121 gcccggcctg cccgcccaca ccaccgtcct gcgcgacgag gacgcccggc tcttccgcgc
    15181 gatcatcggc ggcacccgat tccgcgatct ccagaatcag gaagggcgag acgggcagcc
    15241 cctggaaaag ctccacacct ggcaggagaa aaggtgggtc tacatcgagg gcacgaaagt
    15301 catcgccctc cccgtacgcg aaaaaccctc cgcctatcgg accccgcccc gcaaaggaac
    15361 tccccgcagg tcccgaacta ccgtgcccct cacgctcacc ggtccgcctc cgccgcggcg
    15421 gcctggctga aatccgtccc gtacggcgtt tcccgtttgc ggtgaccgcc cgtcggcgcg
    15481 gtactcgtag aggatcaccg tgcacggctc cgagcaccac acacgacaca ccgcaccgac
    15541 accaccacgc agcaccgagc acaacgccgc atcacgaccc ggaagttgat cactatgacc
    15601 acggccccca ccgaggacca gacccgcgcc gaggacctgc cgccgtcctg ccgcgatctg
    15661 atcggcatcc tcgcccagac cgaccggcgc gacgccttcg cggccctcgc gctcggcgcg
    15721 acctccgtgg cacaggtggc ggagcgggcg gggctgcgcc cggccgccgc cgccgtcgcc
    15781 ctgcagaagc tcgtcgacgg gcggatcgcc gcgtacgacg ccgacgcccg cacctaccgg
    15841 ctgatcgacg acacgttccg gctggccgtc caggcggagg tcaggatctc cggacggggc
    15901 ggcggtgacg gcgcgggggc ctacttccgc aagggacggc tgacctcgat ccccggcaag
    15961 gccgaggtcc gcagccgggt gctcgccgtc gtggccgact ccttcgaggc cggtgtcacc
    16021 tactccgagg ccaaggtcaa cgcgatctgc ggccagtggt tcgacgactg ggtgaccctg
    16081 cgccgggcgc tcgtggacga ggacctgctg cgccgcgacg agtcgggcac gcagtacgaa
    16141 cgcgtatgac cgcatgacac gggtcgtggc gggtgacgtc ggcacggaca cgccggataa
    16201 ggccggtacc gccgataccg ccaaagcagc agataccgcc gatacggcga gccgggcggc
    16261 cgacgtcgtc gcgtgcggcc ggcacaccgg cgcggccgtc ggcgccttca gccgccgccg
    16321 gggcttcgtg gcacggcccg ggcaggtggt cgccgagccg tccgccgacg gccgcgcggt
    16381 ggtgctcaac gtgggcctgg ggcccgccgg ttcggccacg gccgccacgt tccgcgccgc
    16441 ggctgccgcc tcggtacggg ccgtgggccc cgcccgtacg ctccgcctcg acctcgcgct
    16501 ggccgacggc agcggggtcc cggccgccga gcgggcccgg gccgtggcgg agggcgcggt
    16561 gctgggcctg taccgctacg acgagtaccg ctccgctcgg gccgcgagcc cgctggccga
    16621 ggtgatcgtg gcgaccccgg agcggcgggc cgtcgccgag ggcctggccg ccgccgaggc
    16681 cacctgtctg gcccgcgacc tcgtcaactg cccggccggg accctcactc ccccggcgtt
    16741 cgccgaccgg atccgggagc tggcgcacac cgccggcctc gactgcgcgg tgtacgaggg
    16801 agccggcctg acggagctgg gcctcacggg cctgaccgcc gtgggccggg gctcggcgga
    16861 accgccccgg tacgtggagc tgacgtacga cccgccggat gccgaccccg cgctcacggt
    16921 cggcctggtc ggcaagggcg tcacgttcga ctccggcggg ctgtccctga aaccgtccgg
    16981 cgagcggcac gcgatgaagg ccgacatggg cggcgcggcg gccgtcgtcg ccgcgctgac
    17041 cgcactgccc cgcctcggcc tgcccctgcg ggtacgcggc cacctccccc tcgcggagaa
    17101 catgccggac ggcggcgccc tgcgggtggg ggacgtcgta cggcatctgg acggtacgac
    17161 cacggagatc acccacacgg acaacgaggg ccgggtggtg ctggccgacg tcctggtccg
    17221 cgcgagccgc cccggcccgc accgcagcga cctcgtcgtc gacgtggcca ccctcacctc
    17281 cgccgccgtc cacgcgctcg gcacccgcac cggggccctg ttcacaccgg acgaccggct
    17341 ggcccagacg gtgctggccg cttcggagcg ggccggggag tcgttctgcc ggctgccgct
    17401 gctcgcccat gagcggcgga acctgcgctc cgccgtggcg gaccgggtga actgctcgca
    17461 ccggcacggc gacacgatcc aggcggcgct cttcctccag gacttcgtcg cggccggtgt
    17521 cccctgggcc catctggaca tcgccgcgcc cgcgtacaac gacgagggcc cgtacgccga
    17581 agtgccgtac ggcggtaccg ggttcgcggt gcgcacgctg atcgagacgc tgcgcgccct
    17641 ctccgaaggc tcaccggacg tcccctga
//
