BGC0000473: aerucyclamide A biosynthetic gene cluster from Microcystis aeruginosa NIES-298
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 13,853 nt. (total: 13,853 nt).
This entry is originally from NCBI GenBank AM774406.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000473
Short description aerucyclamide A biosynthetic gene cluster from Microcystis aeruginosa NIES-298
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
AM774406.1
via
Compounds
  • aerucyclamide A
  • aerucyclamide B
  • aerucyclamide C
  • aerucyclamide D
Species Microcystis aeruginosa NIES-298 [taxonomy]
References
Chemical products information
aerucyclamide A Evidence: NMR [1], [2]
Copy SMILES
C24H34N6O4S2
Chemical database entries
NPAtlas
aerucyclamide B Evidence: NMR [1], [2]
Copy SMILES
C24H32N6O4S2
Chemical database entries
NPAtlas
aerucyclamide C Evidence: NMR [1], [2]
Copy SMILES
C24H32N6O5S1
Chemical database entries
NPAtlas
aerucyclamide D Evidence: NMR [1], [2]
Copy SMILES
C26H30N6O4S3
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAO82081.1
  • mcaA
868 - 2841 (+) subtilisin-like protein
    copy AA seq
    copy Nt seq
    • CAO82082.1
    • mcaB
    2944 - 3195 (+) hypothetical protein
      copy AA seq
      copy Nt seq
      • CAO82083.1
      • mcaC
      3246 - 3488 (+) hypothetical protein
        copy AA seq
        copy Nt seq
        • CAO82084.1
        • mcaD
        3550 - 5880 (+) adenylation/heterocyclization protein
          copy AA seq
          copy Nt seq
          • CAO82085.1
          • mcaE
          5997 - 6221 (+) microcyclamide precursor protein
            copy AA seq
            copy Nt seq
            • CAO82086.1
            • mcaF
            6516 - 7481 (+) hypothetical protein
              copy AA seq
              copy Nt seq
              • CAO82087.1
              7534 - 8337 (+) hypothetical protein
                copy AA seq
                copy Nt seq
                • CAO82088.1
                8426 - 8773 (+) hypothetical protein
                  copy AA seq
                  copy Nt seq
                  • CAO82089.1
                  • mcaG
                  9166 - 13221 (+) thiazoline oxidase/subtilisin-like protease
                    copy AA seq
                    copy Nt seq
                    Biosynthesis information
                    Annotation changelog

                    Entry version: next

                    Date
                    Changes
                    Submitters
                    Reviewers
                    MIBiG v4 annotathon
                    • (ID: AK53UXEU2X7JUZMX7VY3GZAO)
                    • (ID: OJYAMYQ5UJI73UMKC4YMTVEZ)
                    • (ID: B54ZPFB4PBVBWY2K6JZNBOD5)
                    • (ID: JXNPUXPAL6VYCS4XEXVRJDGK)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 3

                    Date
                    Changes
                    Submitters
                    Reviewers
                    Fix peptidase IDs
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 2

                    Date
                    Changes
                    Submitters
                    Reviewers
                    Migrated from v1.4
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    Updated compound(s) information (NPAtlas curation)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    Submitted
                    • (ID: FGOE6VD55GZRETNYSNOKUJZO)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    Similar known gene clusters from MIBiG 4.0
                    Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                    Click on reference genes to show details of similarities to genes within the current region.
                    Click on an accession to open that entry in the MiBIG database.