BGC0000488: circularin A biosynthetic gene cluster from Clostridium beijerinckii
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Location: 1 - 11,388 nt. (total: 11,388 nt).
This entry is originally from NCBI GenBank AJ566621.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000488
Short description circularin A biosynthetic gene cluster from Clostridium beijerinckii
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Remarks "Only partial expression data in Lactococcus or Enterococcus. No direct data on Clostridium. Same class as enterocin AS-48"
Biosynthetic class(es)
  • RiPP (Head-to-tailcyclized peptide)
Loci NCBI GenBank: AJ566621.1
Compounds
  • circularin A
Species Clostridium beijerinckii [taxonomy]
References
Chemical products information
circularin A
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAD97576.1
  • cfgR
 162 - 938 (+) putative response regulator
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  • CAD97577.1
  • cfgK
 932 - 2209 (+) putative histidine kinase
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  • CAD97578.1
  • cfg02
 2240 - 2839 (-) putative ArgB homologue
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  • CAD97579.1
  • cfg01
 3090 - 3482 (-) hypothetical protein
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  • CAD97580.1
  • cirA
 3788 - 4006 (+) circularin A precursor
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  • CAD97581.1
  • cirB
 4107 - 5852 (+) CirB protein
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  • CAD97582.1
  • cirC
 5833 - 6390 (+) CirC protein
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  • CAD97583.1
  • cirD
 6390 - 7055 (+) ATP-binding protein
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  • CAD97584.1
  • cirE
 7085 - 7234 (+) circularin immunity protein
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  • CAD97585.1
  • cirG
 7302 - 8729 (+) putative hylD family protein
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  • CAD97586.1
  • cirH
 8729 - 9475 (+) ATP binding protein
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  • CAD97587.1
  • cirI
 9466 - 10734 (+) putative ABC transporter permease
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RiPP-specific information
Subclass Head-to-tailcyclized peptide
Cyclic? yes
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: 2QGQPUII4VGQV6OUMHRFLPYN, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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