BGC0000495: actagardine biosynthetic gene cluster from Actinoplanes garbadinensis
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Location: 1 - 38,168 nt. (total: 38,168 nt).
This entry is originally from NCBI GenBank FJ547091.1.

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core biosynthetic genes
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transport-related genes
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resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000495
Short description actagardine biosynthetic gene cluster from Actinoplanes garbadinensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
FJ547091.1
via
Compounds
  • actagardine
Species Actinoplanes garbadinensis [taxonomy]
References
Chemical products information
actagardine Evidence:
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C81H132N20O23
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACR33034.1
 42 - 482 (-) hypothetical protein
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    • ACR33035.1
    		 2375 - 2824 (-) hypothetical protein
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      • ACR33036.1
      		 2876 - 4432 (-) ATPase AAA
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        • ACR33037.1
        		 5391 - 6002 (-) sugar hydrolase
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          • ACR33038.1
          		 5825 - 6484 (-) endoglucanase
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            • ACR33039.1
            		 6627 - 7112 (+) cytosine/adenine deaminase
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              • ACR33040.1
              		 7756 - 8997 (+) hypothetical protein
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                • ACR33041.1
                		 8933 - 9616 (-) hypothetical protein
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                  • ACR33042.1
                  		 10108 - 11901 (-) pyruvate oxidase
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                    • ACR33043.1
                    		 12195 - 12866 (+) hydrolase
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                      • ACR33044.1
                      		 13116 - 14306 (+) aldose epimerase
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                        • ACR33045.1
                        		 14385 - 15521 (+) ABC sugar transport periplasmic component
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                          • ACR33046.1
                          		 15514 - 16572 (+) ABC sugar transport permease
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                            • ACR33047.1
                            		 16569 - 17330 (+) ABC transport protein ATP-binding
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                              • ACR33048.1
                              		 17335 - 18102 (-) methyltransferase
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                                • ACR33049.1
                                		 18120 - 18962 (-) ABC transport permease
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                                  • ACR33050.1
                                  		 18991 - 19896 (-) ABC transport permease
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                                    • ACR33051.1
                                    		 19899 - 21236 (-) substrate binding ABC transporter
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                                      • ACR33052.1
                                      • garA
                                      		 21572 - 21766 (+) actagardine prepeptide
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                                        • ACR33053.1
                                        • garM
                                        		 21837 - 24998 (+) actagardine modification enzyme
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                                          • ACR33054.1
                                          • garO
                                          		 25024 - 26034 (+) monooxygenase
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                                            • ACR33055.1
                                            • garR1
                                            		 26096 - 26791 (-) response regulator
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                                              • ACR33056.1
                                              • garH
                                              		 26885 - 29323 (-) ABC transporter associated permease
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                                                • ACR33057.1
                                                • garT
                                                		 29326 - 30105 (-) ABC transporter
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                                                  • ACR33058.1
                                                  • garK
                                                  		 30220 - 31338 (+) response regulator
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                                                    • ACR33059.1
                                                    • garR
                                                    		 31335 - 31997 (+) response regulator
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                                                      • ACR33060.1
                                                      		 32084 - 34486 (+) penicillin binding protein
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                                                        • ACR33061.1
                                                        		 34448 - 35209 (-) methyltransferase
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                                                          • ACR33062.1
                                                          		 35245 - 36030 (-) hydrolase
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                                                            • ACR33063.1
                                                            		 36152 - 36820 (+) response regulator
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                                                              • ACR33064.1
                                                              		 36829 - 37689 (+) fructose bisphosphate aldolase
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                                                                • ACR33065.1
                                                                		 37590 - >38168 (+) putative hydrolase
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                                                                  Biosynthesis information
                                                                  Annotation changelog

                                                                  Entry version: 4

                                                                  Date
                                                                  Changes
                                                                  Submitters
                                                                  Reviewers
                                                                  2022-10-07
                                                                  Update chemical activity to schema version 2.11
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                  Entry version: 3

                                                                  Date
                                                                  Changes
                                                                  Submitters
                                                                  Reviewers
                                                                  2022-09-15
                                                                  Updated bioactivity data
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                  Entry version: 2

                                                                  Date
                                                                  Changes
                                                                  Submitters
                                                                  Reviewers
                                                                  2019-10-16
                                                                  Migrated from v1.4
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                  Entry version: 1

                                                                  Date
                                                                  Changes
                                                                  Submitters
                                                                  Reviewers
                                                                  2015-06-12
                                                                  Submitted
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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