LOCUS       BGC0000499              4733 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Butyrivibrio fibrisolvens butyrivibriocin OR79 (bvi79) gene,
            complete cds; and unknown genes.
ACCESSION   BGC0000499
VERSION     BGC0000499
KEYWORDS    .
SOURCE      Butyrivibrio fibrisolvens
  ORGANISM  Butyrivibrio fibrisolvens
            Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
            Butyrivibrio.
COMMENT     On Apr 13, 1999 this sequence version replaced AF062647.1.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:44:51
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..4733
                     /db_xref="taxon:831"
                     /mol_type="genomic DNA"
                     /organism="Butyrivibrio fibrisolvens"
     protocluster    1..4733
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2354:>4733]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2355..>4733
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..4733
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..4733
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000499"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..4733
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             <1..160
                     /codon_start=2
                     /note="ORF1"
                     /product="unknown"
                     /protein_id="AAD24811.1"
                     /transl_table=11
                     /translation="MILNHGTLLFEGSMDDLRAEAKVQGYNDNNLEDMFLSMIEADNKQ
                     RKQRAVL"
     CDS             157..876
                     /codon_start=1
                     /note="ORF2"
                     /product="unknown"
                     /protein_id="AAD24812.1"
                     /transl_table=11
                     /translation="MIALELKKEKRTGLVAILFLTGIIGALYVFLNYKIRGNTLLNMPL
                     DPMDVLLTQLYGMIMVLNMFAIVIATSIAYNMEFSGFAIKKMYVLPISMWKVFVAKFLI
                     ITSVFFIAIVIQNAALMWIGISKLGSDKFDMGVFLMFVLYSYITSLPVISFMLMIASLF
                     ENLWVTIGIGVRGFLSAVALQSDHAIYVLSHPFIVMFKPAIAMTAKSDLAVALIAIFET
                     VVFFVIGIVIAENKKSE"
     CDS             886..1635
                     /codon_start=1
                     /note="ORF3"
                     /product="unknown"
                     /protein_id="AAD24813.1"
                     /transl_table=11
                     /translation="MLAIEFKKIKRSWIVPLIFIAPILVVSSGIASLSRYFTPEYTSAW
                     PAMFIQSALVYAYYLLPLSMIVVCVMISARETQNNGILKMLALPVDRAKLSLAKFVVIL
                     TFLFLEILVFFVIFLVAGKIAMTSNNISEDIPLLYLVACCVKLFLTMIPAVALMWAITV
                     IFEKPILSVGLNIFLVLPGILVANTGAWIWYPYCYSGYLISCSLRDFTTETDNARFQLL
                     PFLPCALVMFALALTLSVYRFGKKEMV"
     CDS             1638..1928
                     /codon_start=1
                     /note="ORF4"
                     /product="unknown"
                     /protein_id="AAD24814.1"
                     /transl_table=11
                     /translation="MEKTNVKKIENMGLIACILPVLALVPAIFKIHLAPAVQSVWGIAN
                     VLFVIAGFVLTITALRMKKTRNAVNIIASCICLLWVLILLGVIVVVVVSNM"
     gene            2044..2190
                     /gene="bvi79"
     CDS             2044..2190
                     /codon_start=1
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /gene="bvi79"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /product="butyrivibriocin OR79"
                     /protein_id="AAC19355.1"
                     /sec_met_domain="L_biotic_A (E-value: 7.1e-29, bitscore:
                     88.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKELNALTNPIDEKELEQILGGGNGVIKTISHECHMNTWQFIFT
                     CCS"
     CDS_motif       2044..2112
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MNKELNALTNPIDEKELEQILGG"
                     /locus_tag="bvi79_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       2113..2190
                     /prepeptide="core"
                     /locus_tag="bvi79_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="4.80"
                     /molecular_weight="2767.2"
                     /monoisotopic_mass="2765.3"
                     /core_sequence="GNGVIKTISHECHMNTWQFIFTCCS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNKELNALTNPIDEKELEQILGG"
                     /leader_location="[2043:2112](+)"
                     /alternative_weights="2785.2"
                     /alternative_weights="2803.2"
     CDS             2355..>4733
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     539.6; E-value: 2.5e-163)"
                     /gene_kind="biosynthetic"
                     /note="ORF6"
                     /product="unknown"
                     /protein_id="AAC19356.1"
                     /sec_met_domain="DUF4135 (E-value: 2.9e-75, bitscore:
                     242.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.7e-38, bitscore:
                     120.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSKFGKIYIDYLYDHVLEDVKKNIDVNIKEMPVIKEKVENEIFV
                     KCFKSLVYCMNLARVEEKLIGESPEDRYTFFCENEDAIIGGMEKIFPEMKNQISEEIRG
                     KICYLIKVVDDFVNNYKEISKKFLLENEQIKNINVGGDWHNDKSVIIFEFTKGSKIVFK
                     PTHGRNIEFLKGLSTIFLGREYSSLYDSLTTDEGTWVKFIEHKAIKSEAEIKEFYYNYG
                     KLLYMTYILGINDMHYENLLANGVYPVITDVETIFSSYLFFNIHKLEYDAQYNATKKLL
                     YGTMATGLVPVFTMSEYFGGDVSCLSNRGLKIMVEKLENEYRDDMCIKVAEDMVKSDSH
                     LPNNDIDPLDYGKDILQGFNEADEIFRNNKQKIYKYIDDNFDKVESRIILNMTKAYSKI
                     LRIKNDVKYRMNPELFKELLGKLKRTNQFNKKVYEHEIAELMNGNIPSFYWSAKEKCVY
                     GPVDSSVEKIMDIKGFDIEDVKDIIEYQTADNIIEEQKNLIENAIISSKVLSINYIEKS
                     GKDKSIKAKPATEKMLRENIDKNIILGKDNTIAWLGLMVNDQEQLEYAMVDWSLYSGIS
                     GIGLMYYTEWLNTGDRNAVAVMQLIVNTIKKEYELGRFDTYDISYFCGLTGIYSFIKKV
                     EKIPGIELFGLKESFEKLIEKNIAYTNCYDSLSGVHSAVIYYYGDYKENYFSRKIITSI
                     TYHFMENFNMRMMDATFSFASFAHGYTGLMTSLLCMNRVVKDDRFSILIKKAWEKEKKL
                     KVSDFKWVDKRRADGSSSHYWCHGSCGIMQARLFWYKEEF"
ORIGIN
        1 aggaattcta aatcatggaa cacttttatt cgaaggcagc atggatgacc taagggctga
       61 ggcaaaggtc cagggataca acgataacaa cctggaggac atgttccttt caatgattga
      121 agctgataac aagcaaagaa agcagagggc agtattatga ttgcgcttga gttaaagaag
      181 gaaaagagaa caggacttgt agcaatccta tttttaactg gaattatagg agctttatat
      241 gtgttcttga attataagat tcgaggaaac acacttttaa acatgccact tgatcccatg
      301 gatgtacttc taacgcagct atacggaatg ataatggtac tgaacatgtt tgccattgta
      361 atagcaacca gtattgccta caacatggaa ttttcaggat ttgcaatcaa gaaaatgtat
      421 gtgcttccta taagtatgtg gaaagttttt gtagcaaaat tcctcataat aacaagcgta
      481 ttttttatag ctatagtgat tcaaaacgcc gcgttgatgt ggataggtat aagcaaactg
      541 ggttctgata aatttgatat gggagttttt ctaatgtttg ttttatattc atatatcaca
      601 tctttgccgg tcataagctt tatgttgatg atagcatctt tatttgaaaa cctatgggtg
      661 acaatcggta ttggcgtacg aggattctta agtgctgtag ccttacagtc tgaccatgcc
      721 atatatgtat tgtctcatcc atttatagtg atgtttaaac ctgcaattgc tatgacagcg
      781 aaatcggatt tagcggtagc gctaatagca atatttgaaa ctgtagtatt tttcgtaatc
      841 ggaattgtga ttgccgaaaa taaaaaatca gaataggagg caaaaatgtt agcaatagaa
      901 tttaaaaaga taaaaagatc atggattgtg ccactaatat ttatcgctcc gattttggtg
      961 gtgtcatcag gaatagcaag tttgagtcgt tattttacgc cagaatacac aagtgcatgg
     1021 cctgctatgt ttatacagag tgccctagtg tatgcatatt atctgcttcc actaagcatg
     1081 attgttgtat gtgtaatgat atcagctagg gaaactcaaa ataatggaat tttaaaaatg
     1141 ttggcattgc cagtagatag agcaaaacta tcattagcaa aatttgtagt aatccttaca
     1201 ttcttgttcc tagagatact agttttcttt gtgatttttc tagttgcagg aaaaatagcc
     1261 atgactagta acaatatttc tgaggatatt cctcttttgt acttagtggc atgctgtgtg
     1321 aaattatttt taacaatgat tccagcagtg gcactgatgt gggcaataac agttattttt
     1381 gaaaagccaa ttttatcagt agggttaaat atttttctgg ttcttccagg aattttggtg
     1441 gctaacactg gtgcatggat ttggtatcca tactgttata gcggatattt gatttcctgc
     1501 tctcttagag attttacaac tgaaacagat aatgcgagat ttcagttgtt accatttttg
     1561 ccatgtgcat tagtaatgtt tgcactagca cttacattat cagtttatag atttggaaaa
     1621 aaggagatgg tttaattatg gaaaaaacaa atgtaaagaa aattgaaaac atgggactta
     1681 ttgcatgcat attaccagta ttggcgcttg tacctgcaat ttttaagatt catcttgccc
     1741 cagctgtaca gagtgtgtgg ggaatagcga atgtactttt tgtaatcgca ggattcgttc
     1801 taacaattac agcacttaga atgaaaaaga caagaaacgc agtgaatatc attgcctcat
     1861 gtatttgtct actttgggta cttatccttc ttggcgttat tgtagtagtt gttgtatcta
     1921 atatgtaatt tgttttaaga aaattacaag ttaaaaggga ataattacaa ggtgcaaaaa
     1981 aacaaaagtc ataatgataa actccaatca taatcctatt ggagaaggaa attggaggta
     2041 aatatgaaca aagaacttaa tgcacttaca aatcctattg acgagaagga gcttgagcag
     2101 atcctcggtg gtggcaatgg tgtcatcaag acaatcagcc acgagtgcca catgaacaca
     2161 tggcagttca ttttcacatg ttgctcttaa tccttattta gtagaagcac atacaaatct
     2221 ttttttaaaa ctaataacag aaactataaa cttcacaaca ttgtaaacag ttctcggata
     2281 ggatttttct aggccgcttg ggatgttcct gaagcgcctt tgattttaaa ggaaaaggta
     2341 aattggtggt tggtatgaaa agtaaatttg ggaagattta tattgattat ctctatgatc
     2401 atgttttaga agacgtgaaa aaaaatatcg atgtaaacat aaaggaaatg cctgttataa
     2461 aagaaaaggt ggagaatgag atatttgtaa aatgcttcaa atctctggtt tattgcatga
     2521 atctagcgag agtggaagag aagttaattg gagaaagccc agaggataga tatacttttt
     2581 tttgcgagaa cgaagatgca ataattgggg ggatggaaaa aatctttcca gaaatgaaaa
     2641 atcaaattag cgaagaaatt aggggtaaga tttgctattt gattaaggtt gttgatgact
     2701 ttgtaaataa ctataaggaa attagcaaga aatttttact tgagaatgag cagataaaaa
     2761 atataaatgt aggtggagat tggcacaatg ataaaagtgt aataatcttt gagtttacta
     2821 agggaagtaa aatagttttc aagcctacac atggaagaaa tatagaattt ttaaagggat
     2881 tatcgactat atttttgggg agagaatata gtagtttgta tgattcccta acaactgatg
     2941 aaggtacttg ggttaaattt attgagcaca aggctatcaa atctgaagct gagataaagg
     3001 agttttacta taactatgga aaactgcttt atatgaccta catacttgga ataaatgata
     3061 tgcactatga gaatttactg gcaaatgggg tgtatccagt aatcacagat gtggagacca
     3121 ttttttcatc ttacttattt tttaacatac acaagctgga atacgatgcc cagtataatg
     3181 ctacaaaaaa gcttttatat ggcaccatgg caacaggact tgtccctgtg tttaccatgt
     3241 cggaatattt tggaggcgat gtaagctgcc tatcaaatag gggcctgaag ataatggtag
     3301 aaaaattgga aaatgaatat agagatgata tgtgcatcaa ggtagcagaa gatatggtaa
     3361 aaagcgattc tcatttacca aataacgata tagacccact tgattatgga aaagacattt
     3421 tacaaggctt caatgaggcg gatgaaatct ttagaaataa taagcaaaag atttacaagt
     3481 acattgatga taatttcgac aaagtggaat ctagaattat tctaaatatg acaaaggctt
     3541 attctaagat acttcgtatt aagaatgacg ttaagtatag aatgaatcct gagttattca
     3601 aggagttact tggaaagctc aagagaacaa accagtttaa taagaaggta tatgagcacg
     3661 agatagcaga gcttatgaat ggtaatattc caagcttcta ttggagtgcg aaggaaaaat
     3721 gtgtatacgg tccagttgat tcttccgtag aaaagattat ggatataaag ggctttgata
     3781 tagaggatgt aaaagacata atcgaatatc aaacagctga caatataatt gaagaacaga
     3841 agaatctgat agaaaatgca ataatctcaa gcaaagtgct cagtattaat tatattgaaa
     3901 aaagcggtaa agataagagc ataaaggcta agcctgcaac agagaaaatg cttagagaaa
     3961 atattgataa aaatattatt ctaggtaaag ataacacaat tgcatggctg ggtctgatgg
     4021 ttaatgacca agagcagctt gagtacgcta tggtagattg gtccttgtat tcaggtatta
     4081 gcggaatagg acttatgtac tatacagagt ggttgaatac aggtgacaga aatgccgtag
     4141 cagtaatgca acttatagta aataccataa agaaagaata tgaattagga aggtttgata
     4201 cctatgacat ttcttatttc tgcggactta caggtatcta ttcattcata aaaaaggtag
     4261 aaaaaatacc gggaatagag ctatttggat tgaaagaatc ctttgagaag cttattgaaa
     4321 agaatatcgc atatacgaat tgctatgatt ctctatcagg ggttcattca gctgtgatct
     4381 attactatgg ggattataag gaaaattatt ttagcagaaa aataataaca tccattactt
     4441 atcatttcat ggaaaatttc aacatgcgaa tgatggatgc tacttttagc tttgctagtt
     4501 ttgctcatgg atacactgga ttgatgacat ccttactatg catgaacaga gttgtaaaag
     4561 atgatagatt ttccatcctc attaagaaag cttgggagaa ggaaaagaaa ttaaaagttt
     4621 cagattttaa atgggtggat aaaagaagag ccgatggaag cagctctcac tactggtgcc
     4681 acggttcatg tggaatcatg caggctcgat tattctggta taaagaagaa ttc
//
