LOCUS       BGC0000501              7208 bp    DNA     linear   BCT 10-SEP-2019
DEFINITION  Catenulispora acidiphila DSM 44928 chromosome, complete genome.
ACCESSION   BGC0000501
VERSION     BGC0000501
KEYWORDS    .
SOURCE      Catenulispora acidiphila DSM 44928
  ORGANISM  Catenulispora acidiphila DSM 44928
            Bacteria; Actinomycetota; Actinomycetes; Catenulisporales;
            Catenulisporaceae; Catenulispora.
COMMENT     URL -- http://www.jgi.doe.gov
            JGI Project ID: 4082785
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:45:16
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7208
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[0:2613]"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..2613
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     cand_cluster    1..7208
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..7208
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000501"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..7208
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..2613
                     /locus_tag="Caci_4239"
     CDS             1..2613
                     /codon_start=1
                     /db_xref="InterPro:IPR000719"
                     /db_xref="InterPro:IPR002290"
                     /db_xref="InterPro:IPR007822"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 67.6;
                     E-value: 2.1e-20)"
                     /gene_kind="biosynthetic"
                     /inference="protein motif:PFAM:PF05147"
                     /locus_tag="Caci_4239"
                     /note="PFAM: Lanthionine synthetase C family protein;
                     SMART: serine/threonine protein kinase; KEGG: sma:SAV_7503
                     membrane translocator"
                     /product="serine/threonine protein kinase"
                     /protein_id="ACU73103.1"
                     /sec_met_domain="micKC (E-value: 4.1e-247, bitscore: 810.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2.8e-13, bitscore: 38.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3e-07, bitscore: 17.9,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDRYEAYTMLDRHFYDAVRGVGPATPGFAAGERELPSGWRRYGQ
                     DDWTVVEPTPLELPAQGWKIHASAALDSAEEILAKVYEYCVPRGIAFKFLRSPAALLAR
                     VSKYAPRGYSGKFITIYPSDDAACERILTELGEQLDGLPNPYILSDLRWNAGPLHVRYG
                     AFANRYTVSESGSVVPAMAAPDGTLVPDRRTPVFRTPEWVELPEFLAPQLAARNAVTLN
                     DMPYKVERVLHFSNGGGIYVGRDTRTGDEVVLKEGRPHAGLDARGADAVHRVEHEYAML
                     KRLEGIPGLPHARDLLWVGEHRFLVMDYIDDGVPLSRTMGVRYPLTDHAATDEDRQRYT
                     DWALDIHRQVSETLDAIHERGVVYGDLHMFNVLVRADDSIALLDFEVSCDAVESVRPGL
                     GNPGFSAPATVTGVDRDRYALACLSLALFLPLANMIWLHRPKARDFAAVIAEQFPVPHG
                     FLAEAVTVITGVDDRARPPALNVPVRIEPEPHDWPAMRADLVRSIEASATPERDDRLFP
                     GDIRQFALGGLGLAHGAAGVLYALDVTGAGRFPQYEDWLLRHAKDPGDGARPGLWDGMH
                     GAAFALDHLGHRAEALDIVESCLRDNWEAYASDLAGGLSGIGLNLLHLAERTGENGLAE
                     AGLRAAEIVAERLAAPDTAPTVSGRDGFHAGLMRGHSGQAMLMLRAFDTVGDSRFLDCA
                     AEALQRDLRRCVVRDKQAMHVDEGWRTLPYLDVGSIGIGVALDAYLAVRPDDEDPKFAE
                     AAETIPVAAHSPLYALPGLYSGRAGIILYLAGRTPERHRDPLLAAQVRSLTWHTLPYGG
                     GTAFPGGGLMRLSMDLATGTAGVLLALGAALHDEPVHAPLLAPKTPVPSGAGQPKTGR"
     gene            2619..2774
                     /locus_tag="Caci_4240"
     CDS             2619..2774
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /locus_tag="Caci_4240"
                     /product="hypothetical protein"
                     /protein_id="ACU73104.1"
                     /transl_table=11
                     /translation="MTEEMTLLDLQGMEQTETDSWGGSGHGGGGDSGLSVTGCNGHSGI
                     SLLCDL"
     CDS_motif       2619..2696
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MTEEMTLLDLQGMEQTETDSWGGSGH"
                     /locus_tag="Caci_4240_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       2697..2774
                     /prepeptide="core"
                     /locus_tag="Caci_4240_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="3.50"
                     /molecular_weight="2186.4"
                     /monoisotopic_mass="2185.0"
                     /core_sequence="GGGGDSGLSVTGCNGHSGISLLCDL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTEEMTLLDLQGMEQTETDSWGGSGH"
                     /leader_location="[2618:2696](+)"
                     /alternative_weights="2204.4"
                     /alternative_weights="2222.4"
                     /alternative_weights="2240.4"
     gene            complement(2938..3663)
                     /locus_tag="Caci_4241"
     CDS             complement(2938..3663)
                     /codon_start=1
                     /inference="ab initio prediction:Prodigal:1.4"
                     /locus_tag="Caci_4241"
                     /note="KEGG: hypothetical protein"
                     /product="hypothetical protein"
                     /protein_id="ACU73105.1"
                     /transl_table=11
                     /translation="MPDTPLSALARPRPPALAAASQPPPFRAAIARKLMQGCTALAKHN
                     MPPAGPESASPRRPSRTSLRAPARPRPLTLAAASQPPPFRAAIARKLMQGCTALAKHNM
                     PPVRPESASPRRPSRTSLSARARPRPPTPATASQPPQLRAALACRFMQGRTALAKQNMP
                     PVGSEAASPRRPSQRSSLSAPVRLRLRPQPRAASITAAPPHSNSLIPPPLRSRAAGHRG
                     AVQHLWSRSSGRRLNDRVS"
     gene            3742..5382
                     /locus_tag="Caci_4242"
     CDS             3742..5382
                     /codon_start=1
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR017940"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 276.9; E-value:
                     5.8e-84)"
                     /gene_kind="transport"
                     /inference="protein motif:PFAM:PF00005"
                     /locus_tag="Caci_4242"
                     /note="PFAM: ABC transporter related; ABC transporter
                     transmembrane region; SMART: AAA ATPase; KEGG: sma:SAV_7501
                     ABC transporter ATP-binding membrane translocator, AmfB"
                     /product="ABC transporter related"
                     /protein_id="ACU73106.1"
                     /transl_table=11
                     /translation="MSSAYASAVRHGGAWLPTIGLAALGSTAVTLAVPDVLGAAIDAAA
                     TGHSVAGRLLLAGGLMVFGVLCDMTAGYAAAACTAGTTAWLRLRMTRRVLDAGPAASGS
                     FASGDLLGRVCGNAADAGRAGPGAVTALTAVAPPVGSLVLLAVIDPWLAVAFLAGTAGV
                     ILVLRSFTQGTSRVLRTYLEIQGRIVGRLVESLGGIRTIAAAGTAAAERDRVLAELPDL
                     HAAGRATWRVLARSTFQGAVLGPATLAAVLAVGGVELARGRMTPGELFAASRYASIGTG
                     LGGLTSVFAAVARTRAGAARVGELLDLPVVEYGDQAVPEGSGELTFLAVSSGVLRDIDL
                     TVPGGAAVAVVGPSGSGKSALAALAARLRDPEQGSVLLDGVRLPEIAHDQLRAAVGCAF
                     ERPTLVGATVADAVAPGLPRERVEASARAARADAFVRLLPSGYDTPLAEAPMSGGEAQR
                     IGLARAWTADRLLVLDDATSSLDTATEALISDALLGGARGRTRLIVTHRAATAAQSDLV
                     VWLENGRIRRVGSHALLWQDAAYREVFAA"
     gene            5379..7208
                     /locus_tag="Caci_4243"
     CDS             5379..7208
                     /codon_start=1
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR017940"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 158.1; E-value:
                     4.8e-48)"
                     /gene_kind="transport"
                     /inference="protein motif:PFAM:PF00005"
                     /locus_tag="Caci_4243"
                     /note="PFAM: ABC transporter related; SMART: AAA ATPase;
                     KEGG: sma:SAV_7500 ABC transporter ATP-binding protein,
                     AmfA"
                     /product="ABC transporter related"
                     /protein_id="ACU73107.1"
                     /transl_table=11
                     /translation="MRGREIGFAFSTVRRSSVIALCCWSLLEVPSSALSGIAVAHALDD
                     GFLRHRTGVGLTWIAVLLAAATLAALGARRVFALLGNFVEPLRDVLVRRVVDAAVTRGV
                     AGERDGGAAARLTRQVETVRDSFAGIIIAVRGFVVTALGTAVGALALGPLVAVIVMPPF
                     VVGFGLFLGVLRVAAERQRASVLGEEKVAAAAGPVLAAVRDIAAGGTERYAADLVGGPV
                     LVQAGIERALARVAALRQLCFAIGGWLPALLLLMAGPALLRHGLTAGDLVGGLTFVVSG
                     IQPALRGVMSGLGDSGLRFSITLARLLQATEPVPQPTFAPAESHTDFAGEGLALRGVTF
                     AYGPASEPVLRDLDLTVEPGDHLAVVGPSGIGKSTMAALICGLRPPDAGTVLLGGIDAA
                     SLPPDRLAGIRVLIPQEAYVFAGSLRENLAYLAPQASDDRITASTEAVGADALLARLGG
                     LDALLVPNELSAGERQLLALARAHLSPAPLAVLDEATCHLDPVAERRAEQAFADRGGTL
                     IVIAHRLSSALRAERVLVLDGVRADAGSHEELSERSALYRELLAHWSAGSEPVPAAGSD
                     PALVAGDAHGLDAAARAGLGDGPRQIVANSAVT"
ORIGIN
        1 atggacgacc gctacgaggc gtacacgatg ctcgaccggc atttctacga tgccgttcgt
       61 ggcgtcgggc ccgccacgcc cggcttcgct gccggggagc gggagctgcc gtccgggtgg
      121 cggcgctacg gccaggacga ctggacggtc gtggagccca cgccgctgga gctgccggcg
      181 cagggctgga agatccacgc ctcggccgcc ctggacagcg ccgaggagat actcgccaag
      241 gtctacgagt actgcgtccc gcgcggaatc gccttcaagt tcctgcgctc gccggccgcg
      301 ctgctcgccc gggtgtcgaa gtacgccccg cgcggctact ccggcaagtt catcaccatc
      361 tacccctccg acgacgccgc ctgcgagcgc atcctcaccg agctcggcga acaactcgac
      421 ggtctgccga acccctacat cctcagcgat ctgcgctgga acgccggtcc tctgcacgtc
      481 cgctacggcg ccttcgccaa tcgctacacc gtctccgaga gcggttcggt ggtgccggcg
      541 atggccgcgc ccgacgggac gctggtcccg gaccggcgca cgccggtgtt ccgcacgccg
      601 gagtgggtgg agctgccgga gttcctggcg ccgcagctgg ctgcgcgcaa cgccgtgacg
      661 ctcaacgaca tgccgtacaa ggtggagcgc gttctgcact tctccaacgg cggcggcata
      721 tatgtcggcc gtgacacgcg caccggcgac gaggtcgtgc tcaaggaggg gcggccgcac
      781 gccggactgg acgcccgcgg cgccgacgcc gtgcaccgcg tcgagcacga gtacgcgatg
      841 ctcaaacgcc tggagggcat acccggcttg ccgcatgcca gggacctgct ttgggtcggc
      901 gagcaccgct tcctggtcat ggactacatc gacgacggcg tcccgttgag ccgcacgatg
      961 ggagtccggt atccgctgac cgaccacgcg gcgaccgatg aggaccgcca gcgctacacc
     1021 gactgggctc tggacatcca ccgccaggtc agcgagacgc tggacgccat ccacgagcgt
     1081 ggcgtcgtct acggcgacct gcacatgttc aacgtgctgg tgcgcgccga cgactccata
     1141 gccctgctgg acttcgaagt gtcctgcgac gccgtcgagt cggtccgtcc cggtctgggc
     1201 aaccccggct tcagcgcgcc ggcgacggtg accggcgtcg accgcgaccg ctacgcgctg
     1261 gcctgtctga gcctggcgct gttcctgccg ctggcgaaca tgatctggct gcaccgtccg
     1321 aaggcgcgcg acttcgccgc cgtgatcgcc gagcagttcc cggtcccgca cggcttcctc
     1381 gccgaggcgg tcacggtgat caccggtgtc gacgaccgtg cccggccgcc ggcgctgaac
     1441 gtcccggtcc ggatcgagcc cgagccgcac gactggcccg cgatgcgcgc cgatctggtc
     1501 cgctccatcg aggccagcgc caccccggag cgcgacgacc ggctgttccc cggcgacatc
     1561 aggcagttcg cactcggcgg gctcgggctc gctcacggcg cggccggcgt gctgtacgcc
     1621 ctcgacgtca ccggcgccgg acgcttcccg cagtatgagg actggctgct gcggcacgcc
     1681 aaggaccccg gcgacggcgc gcgccccggc ttgtgggacg gcatgcacgg cgccgccttc
     1741 gccctggacc acctcggcca ccgcgccgaa gccctggaca tcgtcgagtc ctgtctgcgc
     1801 gacaactggg aggcctatgc ctccgacctc gccggcggct tgtcagggat cggactcaac
     1861 ctgctgcacc tggccgagcg caccggcgag aacggactcg ccgaagccgg tctgcgcgcc
     1921 gccgagatcg tcgccgaacg gctcgccgcc ccggacaccg cgccgaccgt ctccggacgc
     1981 gacggcttcc acgccgggct gatgcgcggg cactccgggc aggcgatgct gatgctgcgc
     2041 gccttcgaca ccgtcggcga cagccggttc ctggactgcg ccgccgaggc cctgcaacgg
     2101 gatctgcgcc ggtgtgtagt ccgggacaag caggccatgc acgtcgacga gggctggcgc
     2161 accctgccgt acttggacgt cggcagcatc ggcatcggcg tggcgctgga cgcctatctg
     2221 gcggtccgcc ccgacgacga ggacccgaag ttcgccgagg ccgccgagac catccccgtg
     2281 gccgcgcact ccccgctgta cgccctgccg ggcctgtact ccgggcgcgc cgggatcatc
     2341 ctctacctgg ccggccggac ccccgagcgt caccgcgacc cgctgctcgc cgcccaggtg
     2401 cggagcctga cgtggcacac gctgccctac ggcggcggca cggcgttccc cggcggcggg
     2461 ctgatgcgcc tgtccatgga cctggccacc gggaccgcag gggtcctgct ggccctgggc
     2521 gcggccctgc acgacgagcc ggtgcacgca ccgctgctcg cccccaagac tcccgtgccg
     2581 tccggcgcgg ggcagccaaa aacaggaagg tgaagaagat gaccgaggag atgactctgc
     2641 tcgacctgca gggcatggag cagaccgaga ccgacagctg gggcggcagc ggccacggcg
     2701 gcggcggcga ctcgggcctg agcgtcaccg gctgcaacgg ccacagcggc atcagcctgc
     2761 tctgcgacct ctgatcgacc accctgcggg gtgatcggac cggcccgcgc ggccggccca
     2821 ccacatagcg cggcggcccc ggacggctga cattcgcccg gggccgccga cgcgaggtcg
     2881 gtaccagcag gacggccgcg gcagcccgtc ggccacccgg cacccccgcc ctacccccta
     2941 tgacacccga tcgttgaggc ggcgtccaga tgagcggctc cacaagtgct gtacggcacc
     3001 gcgatggccc gctgcccggg accggagcgg cggcggtatg agggagttag agtgtggcgg
     3061 tgcggcggtg attgaggccg cgcgcggttg cggtcgcagt cggagtcgga ctggcgcgct
     3121 gagcgacgac ctttgcgatg gccgcctcgg gctggctgcc tccgatccca ctggcggcat
     3181 gttctgcttc gcgagggctg tgcggccctg catgaacctg cacgcgagtg ccgctcgcaa
     3241 ctgcggtggc tggctggcag ttgcgggtgt cggcggtcgg ggtcgggccc gcgcgctgag
     3301 agatgtgcgc gatggtcgcc tgggactggc tgactccggt ctgactggcg gcatgttgtg
     3361 cttcgcgagt gctgtgcagc cctgcatgag tttccgcgcg attgccgctc ggaacggcgg
     3421 aggctggctg gcagctgcga gcgttagcgg tcgcggccgg gctggcgccc tgagggatgt
     3481 gcgcgatggt cgcctgggac tggctgattc cggtccggct ggcggcatgt tgtgcttcgc
     3541 gagtgctgtg cagccctgca tgagtttccg cgcgattgcc gctcggaacg gcggaggctg
     3601 gctggcagct gcgagtgccg gcggtcgcgg ccgggccagc gcgctcagcg gcgtgtcggg
     3661 catcgcgaat gctgcgcaga ccggtactag ccgcactcag aatgttgcgt gccgccgcca
     3721 gccgacgatc ggtccggccg catgagcagt gcctacgcga gcgcggtccg ccatggcgga
     3781 gcttggttgc ccaccatcgg tctggcagcc ctgggctcca ccgccgtcac gctggccgtg
     3841 cctgatgtgc tcggcgccgc catcgacgct gcggcgaccg ggcacagcgt cgccgggcgg
     3901 ctcctgctcg ccggcgggtt gatggtcttc ggcgtgctct gcgacatgac cgcgggctac
     3961 gccgctgcgg cctgtaccgc cggtaccacc gcctggctgc ggttgcggat gacgcggcgg
     4021 gtgctggatg ccgggccggc cgccagtggg tccttcgcct cgggcgattt gctggggcgg
     4081 gtgtgcggta atgccgctga tgccgggcgg gccgggccgg gtgccgtcac cgcgctgacc
     4141 gcggttgcgc cgccggtggg gagtctggtg ctgctcgctg tcatcgatcc ctggcttgcc
     4201 gtggcgttcc tggccggtac cgccggggtc atcctggtgc tgcgttcctt tactcagggc
     4261 acttctcgcg ttctgcggac ctacttggag attcagggtc ggattgtcgg gcggctggtc
     4321 gaatcgctgg gcggcatccg taccatcgcc gctgccggga ccgctgccgc tgagcgcgat
     4381 cgcgttctgg ccgagttgcc cgacctgcat gccgccgggc gcgccacctg gcgggtcctg
     4441 gcgcgctcga cgttccaggg tgccgtgctc gggccggcca cgctcgccgc ggtgctggct
     4501 gtcggcggtg tggagctggc gcgcggccgc atgacgcccg gcgagctgtt cgccgccagt
     4561 cgctacgcct ccatcggtac cgggctcggc ggcctcacct cggtgttcgc cgccgtcgca
     4621 cgtacccggg ccggtgcggc gcgcgtcggc gagctgctgg acctcccagt ggtcgaatac
     4681 ggcgatcagg ccgttcccga aggcagcggc gagttgacgt tcctggccgt gtcctccggc
     4741 gtcctgcgcg acatcgacct gacggtcccc ggcggagccg ccgtcgccgt ggtcggtccc
     4801 tccggctccg gcaagtcggc gctcgccgcg ctcgccgccc ggctccgcga ccccgagcaa
     4861 ggcagcgtcc tgctggacgg cgtgcggctg ccagagatcg cacacgacca actccgcgcc
     4921 gccgtgggct gtgccttcga gcgcccgacg ctcgtcggcg cgaccgtcgc cgacgccgtc
     4981 gccccaggac tgccgcgcga acgcgtggaa gcctcagcgc gggcagcccg cgcggacgcc
     5041 ttcgtccgcc tcctgccctc cggctacgac acccccctgg ccgaagcgcc gatgtccggg
     5101 ggagaggcgc agcggatcgg gctcgctcgc gcctggaccg ccgaccgcct cctcgtgctg
     5161 gacgatgcga cctccagcct ggacaccgcc accgaggcac tcatcagcga cgccctgctc
     5221 ggcggcgcgc gcggccggac acggctgatc gtgacgcacc gcgcggcgac ggcggcacag
     5281 tccgatctgg tcgtgtggct cgagaacgga cggatccggc gggtcggcag ccacgccctg
     5341 ctgtggcagg acgctgccta ccgggaggtg ttcgccgcat gaggggacgc gagatcggct
     5401 tcgctttcag cacagtgcgg cgctcctctg tcatcgcgct gtgctgctgg tccctgctgg
     5461 aggtcccgtc ctcggcgctg tccggcatcg ccgtggcgca cgcgctcgac gacggcttcc
     5521 tgcgccaccg caccggcgtc ggcctgacct ggatcgcggt gctgctggcc gccgccacac
     5581 tggcggcgct cggcgcgcgc cgcgtcttcg cgttgctggg caacttcgtc gagccgctgc
     5641 gtgacgtcct ggtccgccgc gtcgtggacg ccgccgtgac gcgcggcgtg gcaggcgagc
     5701 gtgacggcgg cgccgcggcc cgcctgaccc gccaggtgga gacggtccgc gactccttcg
     5761 ccggcatcat catcgccgtc cgcgggttcg tcgtcaccgc gctcgggacg gcggtcggcg
     5821 cgctcgcgct gggtccgctg gtcgcggtga tcgtgatgcc gccgttcgtg gtcgggttcg
     5881 ggctcttcct cggcgtgctg cgggtcgccg ccgaacgcca gcgggccagt gtcctcggcg
     5941 aggagaaggt ggccgctgcc gcaggtccgg tcctggcggc ggtgcgcgac atcgcggcgg
     6001 gcggaaccga gcgctacgcg gccgatctgg tcggcgggcc ggtcctggtg caggccggca
     6061 tcgagcgggc gctggcgcgg gtcgccgcgc tgcgccagct gtgcttcgcc atcggcggct
     6121 ggctgcccgc gctgctgttg ctgatggccg gtccggcgct gctgcggcac gggctcaccg
     6181 ccggcgatct ggtcggcggg ctgacgttcg tggtctcggg catccagccc gcgctgcgcg
     6241 gcgtcatgtc agggctcggt gacagcggtc tgcgattctc gatcacgttg gcccgcttgc
     6301 tgcaagccac cgaaccggtg ccgcagccga cgttcgcccc ggccgaatcg cacaccgact
     6361 tcgccggtga ggggctggcg ctgcgcggcg tcaccttcgc ctacggcccg gcctccgagc
     6421 cggtgctgcg cgatctcgat ctgaccgtcg aacccggcga tcatctcgcg gtcgtcgggc
     6481 ccagcgggat cggcaaatcc accatggccg ccctcatttg cggattgcgg ccgccggacg
     6541 ccggaaccgt tttgctgggc ggcattgatg cggcgagcct gcctccggac cgccttgcgg
     6601 gaatacgagt tttgattcct caggaagcct atgtattcgc cggatcgctt cgcgaaaacc
     6661 ttgcgtatct cgcgccacaa gcgtccgacg atcgcatcac cgcctccacc gaagccgtgg
     6721 gcgccgacgc cctcctggcc cgcctcggcg gcctggacgc gctgctggtc cccaacgagc
     6781 tgtcggccgg cgagcgacag ctgctggcgc tggcccgcgc gcatctgtcg ccggcgccgc
     6841 tggcggtcct ggacgaggcg acgtgccacc tggacccggt cgccgaacgc cgtgccgagc
     6901 aagccttcgc cgaccgcggc ggcaccctga tcgtcatcgc gcaccggctc agctccgcgc
     6961 tgcgcgccga gcgggtcctg gtcttggacg gcgtgcgcgc cgacgcggga agccacgagg
     7021 agctcagcga acgctccgcg ctgtaccgcg agctgctggc gcactggtcc gccggctcgg
     7081 agccggtccc ggccgccggc tcagatccag ccctcgtcgc gggcgatgcg cacggcctcg
     7141 atgcggctgc gcgcgccggt cttggagatg gccctcgaca gatagttgcg aacagtgccg
     7201 ttacttaa
//
