BGC0000502 - 1 region(s) - antiSMASH results

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	terpene-precursor,lanthipeptide-class-ii	1	16,018	High	cerecidin/cerecidin A1/cerecidin A2/cerecidin A3/cerecidin A4/cerecidin A5/cerecidin A6/cerecidin A7	ribosomal:RiPP:Lanthipeptide

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 16,019
Label		BGC0000502

Tailoring functions

Hydrolases: protease

cerP: alkaline serine protease, subtilase family

smcogs: SMCOG1075: alkaline serine protease, subtilase family

Lyases: cyclase

cerM: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000502.5	2.00	ribosomal	cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7	Bacillus cereus
BGC0000504.5	0.56	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000554.4	0.46	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000500.5	0.42	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0001210.5	0.41	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000517.4	0.39	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0001555.4	0.39	ribosomal	colicin V	Escherichia coli chi7122
BGC0000590.5	0.38	ribosomal	microcin N	Escherichia coli
BGC0000527.5	0.37	ribosomal	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0000525.5	0.37	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000502.5	1.00	ribosomal	cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7	Bacillus cereus
BGC0000504.5	0.62	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000554.4	0.56	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000500.5	0.54	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0001210.5	0.53	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000517.4	0.52	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0001555.4	0.52	ribosomal	colicin V	Escherichia coli chi7122
BGC0000590.5	0.51	ribosomal	microcin N	Escherichia coli
BGC0000527.5	0.51	ribosomal	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0000525.5	0.50	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis

Similar known clusters from MIBiG 4.0

Lanthipeptide predictions

Lanthipeptide(s) for cerM

cerA7

Leader:

MSKGYKFTKEELVEAWKDPQVREKLKDLPNHPSGKALNELSEEELAEIQGA

Core:

SDVQPETTPLCVGVIIGITASIKICK

Core with dehydrations:

DhaDVQPEDhbDhbPLCysVGVIIGIDhbADhaIKICysK

antiSMASH-DB 4.0 matches for cerA7

100.0%

NZ_CP067069.1and 13 others:

NZ_CP085413.1 Lanthipeptides: LIS80_RS25350_lanthipeptideNZ_JH792105.1 Lanthipeptides: II5_RS26960_lanthipeptideNZ_JH792240.1 Lanthipeptides: IIK_RS26240_lanthipeptideNZ_MOOT01000061.1 Lanthipeptides: BK765_RS23985_lanthipeptideNZ_NTUF01000024.1 Lanthipeptides: CN379_RS26680_lanthipeptideNZ_NVCZ01000001.1 Lanthipeptides: COK75_RS01180_lanthipeptideNZ_NVDK01000008.1 Lanthipeptides: COK95_RS05665_lanthipeptideNZ_NVEA01000001.1 Lanthipeptides: COL15_RS00010_lanthipeptideNZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08190_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20675_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19560_lanthipeptideNZ_WBPE01000025.1 Lanthipeptides: F8161_RS14435_lanthipeptideNZ_WBPK01000016.1 Lanthipeptides: F8167_RS15685_lanthipeptide

Lanthipeptides: JCR32_RS24620_lanthipeptide

1

SDVQPETTPLCVGVIIGITASIKICK

26

SDVQPETTPLCVGVIIGITASIKICK

1

SDVQPETTPLCVGVIIGITASIKICK

26

96.2%

NZ_LDKE01000067.1:

Lanthipeptides: ABB04_RS19960_lanthipeptide

1

SDVQPETTPLCVGVIIGITASIKICK

26

SDV+PETTPLCVGVIIGITASIKICK

1

SDVKPETTPLCVGVIIGITASIKICK

26

92.3%

NZ_CP067069.1and 33 others:

NZ_CP085413.1 Lanthipeptides: LIS80_RS25380_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25375_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25370_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25365_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25360_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25355_lanthipeptideNZ_JH792105.1 Lanthipeptides: II5_RS26955_lanthipeptideNZ_LDKE01000067.1 Lanthipeptides: ABB04_RS19955_lanthipeptideNZ_LDKE01000067.1 Lanthipeptides: ABB04_RS19940_lanthipeptideNZ_LDKE01000067.1 Lanthipeptides: ABB04_RS19935_lanthipeptideNZ_MOOT01000061.1 Lanthipeptides: BK765_RS23995_lanthipeptideNZ_MOOT01000061.1 Lanthipeptides: BK765_RS23990_lanthipeptideNZ_NVEA01000001.1 Lanthipeptides: COL15_RS00005_lanthipeptideNZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08185_lanthipeptideNZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08180_lanthipeptideNZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08175_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20670_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20665_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20660_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20655_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20650_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20645_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19555_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19550_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19545_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19540_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19535_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19530_lanthipeptideNZ_WBPE01000025.1 Lanthipeptides: F8161_RS14445_lanthipeptideNZ_WBPE01000025.1 Lanthipeptides: F8161_RS14440_lanthipeptideNZ_WBPK01000016.1 Lanthipeptides: F8167_RS15680_lanthipeptideNZ_WBPK01000016.1 Lanthipeptides: F8167_RS15675_lanthipeptideNZ_WBPK01000016.1 Lanthipeptides: F8167_RS15670_lanthipeptide

Lanthipeptides: JCR32_RS24625_lanthipeptide

1

SDVQPETTPLCVGVIIGITASIKICK

26

SDVQPETTPLCVGVIIG+T SIKICK

1

SDVQPETTPLCVGVIIGLTTSIKICK

26

with 110 more sequence matches

Only the first 10 are displayed here.

88.5%

NZ_CP016020.1:

Lanthipeptides: A9C19_RS17970_lanthipeptide

1

SDVQPETTPLCVGVIIGITASIKIC

25

SDVQPETTPLCVGVIIG+T SIKIC

1

SDVQPETTPLCVGVIIGLTTSIKIC

25

73.1%

NZ_JH792105.1:

Lanthipeptides: II5_RS26950_lanthipeptide

1

SDVQPETTPLCVGVIIGITAS

21

SDVQPETTPLCVGVIIG+T S

1

SDVQPETTPLCVGVIIGLTTS

21

71.4%

NZ_CP092966.1:

Lanthipeptides: KM149_RS02085_lanthipeptide

1

SDVQPETTPLCVGVIIGITASIKIC

25

SDV+PETTPLCVGVI G+T SIK C

1

SDVKPETTPLCVGVIAGLTYSIKKC

25

69.2%

NZ_JACSMH010000008.1and 2 others:

NZ_JACSMX010000006.1 Lanthipeptides: KNQ03_RS15615_lanthipeptideNZ_JACSMZ010000005.1 Lanthipeptides: KNQ06_RS16025_lanthipeptide

Lanthipeptides: KNP89_RS14470_lanthipeptide

2

DVQPETTPLCVGVIIGITASIKICK

26

DVQPETTP CVGVI+G+T S+ CK

2

DVQPETTPFCVGVIVGVTISLSKCK

26

65.4%

NZ_JAOVZP010000016.1and 3 others:

NZ_NHVL01000036.1 Lanthipeptides: CEU70_RS27720_lanthipeptideNZ_NTYE01000081.1 Lanthipeptides: CN490_RS28165_lanthipeptideNZ_NVMN01000027.1 Lanthipeptides: CON30_RS23205_lanthipeptide

Lanthipeptides: OF830_RS26725_lanthipeptide

1

SDVQPETTPLCV-GVIIGITASIKIC

25

SDVQPETTP CV + GI SIK C

1

SDVQPETTPACVTALTTGIIFSIKWC

26

63.0%

NZ_JAHHYI010000012.1:

Lanthipeptides: KM925_RS25405_lanthipeptide

1

SDVQPETTPLCVGVIIGITASIKICK

26

DVQPETTP CVG GIT I I K

1

GDVQPETTPACVGA--GITVGIAISK

24

60.7%

NZ_CP062165.1and 5 others:

NZ_CP062165.1 Lanthipeptides: JNUCC31_RS17170_lanthipeptideNZ_QICW01000005.1 Lanthipeptides: DEU73_RS14620_lanthipeptideNZ_QICW01000005.1 Lanthipeptides: DEU73_RS14620_lanthipeptideNZ_QLLI01000007.1 Lanthipeptides: DET54_RS17335_lanthipeptideNZ_QLLI01000007.1 Lanthipeptides: DET54_RS17335_lanthipeptide

Lanthipeptides: JNUCC31_RS17170_lanthipeptide

1

SDVQPETTPLC---VGVIIGITASIKIC

25

+DVQPETTPLC VGV IG+ S+ C

1

ADVQPETTPLCGFLVGVGIGVILSVTSC

28

60.7%

NZ_JAOVZP010000016.1and 1 other:

NZ_JAOVZP010000016.1 Lanthipeptides: OF830_RS26675_lanthipeptide

Lanthipeptides: OF830_RS26680_lanthipeptide

1

SDVQPETTPLC--VGVIIGITASIKICK

26

DV PETTPLC +GV GI S ICK

1

GDVSPETTPLCITIGVGGGIAISKLICK

28

60.7%

NZ_LN831278.1:

Lanthipeptides: BN1360_RS08840_lanthipeptide

1

SDVQPETTPLC---VGVIIGITASIKIC

25

+DVQPETTPLC VGV IG+ S+ C

1

ADVQPETTPLCGFFVGVGIGVILSVAKC

28

59.3%

NZ_FTML01000041.1:

Lanthipeptides: BW937_RS20030_lanthipeptide

1

SDVQPETTPLCVGVIIGITASIKICK

26

DVQPE+TP CVG GIT I I K

1

GDVQPESTPACVGA--GITVGIAISK

24

MIBiG 4.0 matches for cerA7

18.9%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

7

TTPLCVGVIIGITA

20

T P G+I+GI A

1

TDPAVTGLILGIVA

14

cerA6

Leader:

MSKGYKFTKEELVEAWKDPQVREKLNDLPKHPSGKALNELSEEELAEIQGA

cerA5

Leader:

MSKGYKFTKEELVEAWKDPQVREKLNDLPKHPSGKALNELSEEELAEIQGA

cerA4

Leader:

MSKGYKFTKEELVEAWKDPQVREKLKDLPKHPSGKALNELSEEELAEIQGA

cerA3

Leader:

MSKGYKFTKEELVEAWKDPQVREKLNDLPKHPSGKALNELSEEELAEIQGA

cerA2

Leader:

MSKGYKFTKEELVEAWKDPQVREKLKDLPKHPSGKALNELSEEELAEIQGA

cerA1

Leader:

MSKGYKFTKEELVEAWKDPQVREKLKDLPKHPSGKALNELSEEELAEIQGA

Shared core:

SDVQPETTPLCVGVIIGLTTSIKICK

Core with dehydrations:

DhaDVQPEDhbDhbPLCysVGVIIGLDhbDhbDhaIKICysK

antiSMASH-DB 4.0 matches for cerA6

100.0%

NZ_CP067069.1and 33 others:

NZ_CP085413.1 Lanthipeptides: LIS80_RS25380_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25375_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25370_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25365_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25360_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25355_lanthipeptideNZ_JH792105.1 Lanthipeptides: II5_RS26955_lanthipeptideNZ_LDKE01000067.1 Lanthipeptides: ABB04_RS19955_lanthipeptideNZ_LDKE01000067.1 Lanthipeptides: ABB04_RS19940_lanthipeptideNZ_LDKE01000067.1 Lanthipeptides: ABB04_RS19935_lanthipeptideNZ_MOOT01000061.1 Lanthipeptides: BK765_RS23995_lanthipeptideNZ_MOOT01000061.1 Lanthipeptides: BK765_RS23990_lanthipeptideNZ_NVEA01000001.1 Lanthipeptides: COL15_RS00005_lanthipeptideNZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08185_lanthipeptideNZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08180_lanthipeptideNZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08175_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20670_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20665_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20660_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20655_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20650_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20645_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19555_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19550_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19545_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19540_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19535_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19530_lanthipeptideNZ_WBPE01000025.1 Lanthipeptides: F8161_RS14445_lanthipeptideNZ_WBPE01000025.1 Lanthipeptides: F8161_RS14440_lanthipeptideNZ_WBPK01000016.1 Lanthipeptides: F8167_RS15680_lanthipeptideNZ_WBPK01000016.1 Lanthipeptides: F8167_RS15675_lanthipeptideNZ_WBPK01000016.1 Lanthipeptides: F8167_RS15670_lanthipeptide

Lanthipeptides: JCR32_RS24625_lanthipeptide

1

SDVQPETTPLCVGVIIGLTTSIKICK

26

SDVQPETTPLCVGVIIGLTTSIKICK

1

SDVQPETTPLCVGVIIGLTTSIKICK

26

96.2%

NZ_CP016020.1:

Lanthipeptides: A9C19_RS17970_lanthipeptide

1

SDVQPETTPLCVGVIIGLTTSIKIC

25

SDVQPETTPLCVGVIIGLTTSIKIC

1

SDVQPETTPLCVGVIIGLTTSIKIC

25

92.3%

NZ_CP067069.1and 13 others:

NZ_CP085413.1 Lanthipeptides: LIS80_RS25350_lanthipeptideNZ_JH792105.1 Lanthipeptides: II5_RS26960_lanthipeptideNZ_JH792240.1 Lanthipeptides: IIK_RS26240_lanthipeptideNZ_MOOT01000061.1 Lanthipeptides: BK765_RS23985_lanthipeptideNZ_NTUF01000024.1 Lanthipeptides: CN379_RS26680_lanthipeptideNZ_NVCZ01000001.1 Lanthipeptides: COK75_RS01180_lanthipeptideNZ_NVDK01000008.1 Lanthipeptides: COK95_RS05665_lanthipeptideNZ_NVEA01000001.1 Lanthipeptides: COL15_RS00010_lanthipeptideNZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08190_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20675_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19560_lanthipeptideNZ_WBPE01000025.1 Lanthipeptides: F8161_RS14435_lanthipeptideNZ_WBPK01000016.1 Lanthipeptides: F8167_RS15685_lanthipeptide

Lanthipeptides: JCR32_RS24620_lanthipeptide

1

SDVQPETTPLCVGVIIGLTTSIKICK

26

SDVQPETTPLCVGVIIG+T SIKICK

1

SDVQPETTPLCVGVIIGITASIKICK

26

with 101 more sequence matches

Only the first 10 are displayed here.

88.5%

NZ_LDKE01000067.1:

Lanthipeptides: ABB04_RS19960_lanthipeptide

1

SDVQPETTPLCVGVIIGLTTSIKICK

26

SDV+PETTPLCVGVIIG+T SIKICK

1

SDVKPETTPLCVGVIIGITASIKICK

26

80.8%

NZ_JH792105.1:

Lanthipeptides: II5_RS26950_lanthipeptide

1

SDVQPETTPLCVGVIIGLTTS

21

SDVQPETTPLCVGVIIGLTTS

1

SDVQPETTPLCVGVIIGLTTS

21

75.0%

NZ_CP092966.1:

Lanthipeptides: KM149_RS02085_lanthipeptide

1

SDVQPETTPLCVGVIIGLTTSIKIC

25

SDV+PETTPLCVGVI GLT SIK C

1

SDVKPETTPLCVGVIAGLTYSIKKC

25

69.2%

NZ_JACSMH010000008.1and 2 others:

NZ_JACSMX010000006.1 Lanthipeptides: KNQ03_RS15615_lanthipeptideNZ_JACSMZ010000005.1 Lanthipeptides: KNQ06_RS16025_lanthipeptide

Lanthipeptides: KNP89_RS14470_lanthipeptide

1

SDVQPETTPLCVGVIIGLTTSIKICK

26

DVQPETTP CVGVI+G+T S+ CK

1

GDVQPETTPFCVGVIVGVTISLSKCK

26

61.5%

NZ_JACSPU010000002.1:

Lanthipeptides: H9630_RS06775_lanthipeptide

1

SDVQPETTPLCVGVII-GLTTSIKIC

25

SDV PETTP CV GL SIK C

1

SDVAPETTPACVAAFATGLLFSIKFC

26

61.5%

NZ_JAOVZP010000016.1and 3 others:

NZ_NHVL01000036.1 Lanthipeptides: CEU70_RS27720_lanthipeptideNZ_NTYE01000081.1 Lanthipeptides: CN490_RS28165_lanthipeptideNZ_NVMN01000027.1 Lanthipeptides: CON30_RS23205_lanthipeptide

Lanthipeptides: OF830_RS26725_lanthipeptide

1

SDVQPETTPLCV-GVIIGLTTSIKIC

25

SDVQPETTP CV + G+ SIK C

1

SDVQPETTPACVTALTTGIIFSIKWC

26

60.7%

NZ_CP062165.1and 5 others:

NZ_CP062165.1 Lanthipeptides: JNUCC31_RS17170_lanthipeptideNZ_QICW01000005.1 Lanthipeptides: DEU73_RS14620_lanthipeptideNZ_QICW01000005.1 Lanthipeptides: DEU73_RS14620_lanthipeptideNZ_QLLI01000007.1 Lanthipeptides: DET54_RS17335_lanthipeptideNZ_QLLI01000007.1 Lanthipeptides: DET54_RS17335_lanthipeptide

Lanthipeptides: JNUCC31_RS17170_lanthipeptide

1

SDVQPETTPLC---VGVIIGLTTSIKIC

25

+DVQPETTPLC VGV IG+ S+ C

1

ADVQPETTPLCGFLVGVGIGVILSVTSC

28

60.7%

NZ_LN831278.1:

Lanthipeptides: BN1360_RS08840_lanthipeptide

1

SDVQPETTPLC---VGVIIGLTTSIKIC

25

+DVQPETTPLC VGV IG+ S+ C

1

ADVQPETTPLCGFFVGVGIGVILSVAKC

28

59.3%

NZ_JAHHYI010000012.1:

Lanthipeptides: KM925_RS25405_lanthipeptide

1

SDVQPETTPLCVGVIIGLTTSIKICK

26

DVQPETTP CVG G+T I I K

1

GDVQPETTPACVGA--GITVGIAISK

24

58.6%

NZ_JAOVZP010000016.1and 3 others:

NZ_NHVL01000036.1 Lanthipeptides: CEU70_RS27725_lanthipeptideNZ_NTYE01000081.1 Lanthipeptides: CN490_RS28170_lanthipeptideNZ_NVMN01000027.1 Lanthipeptides: CON30_RS23200_lanthipeptide

Lanthipeptides: OF830_RS26730_lanthipeptide

1

SDVQPETTPLC-VGVIIGLTT--SIKICK

26

SDVQPETTP C V IG T S++ CK

1

SDVQPETTPACAVAFTIGATVIFSVRNCK

29

MIBiG 4.0 matches for cerA6

19.2%

BGC0000580.3 (EGD17355.1):

Lasso peptide: xanthomonin II or xanthomonin I

9

PLCVGVIIGLTT

20

PL + G+TT

3

PLAGEEMGGITT

14

13.5%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

7

TTPLCVGVIIGL

18

T P G+I+G+

1

TDPAVTGLILGI

12

11.8%

BGC0000535.4 (ADJ56352.1):

Lanthipeptide: nisin A

20

TSIKIC

25

TSI +C

2

TSISLC

7

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Detailed terpene predictions

Product predictions:

Class	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor	FPP	C15	acyclic	PP
diterpene precursor	GGPP	C20	acyclic	PP
sesterterpene precursor	GFPP	C25	acyclic	PP
triterpene precursor	HPP	C30	acyclic	PP

Genes with terpene domains:

comQ: PT_FPPS_like

Domain 1 (59 - 305): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

Identified secondary metabolite regions using strictness 'relaxed'

Legend:

Lanthipeptide(s) for cerM

antiSMASH-DB 4.0 matches for cerA7

MIBiG 4.0 matches for cerA7

antiSMASH-DB 4.0 matches for cerA6

MIBiG 4.0 matches for cerA6

Legend: