BGC0000503: cinnamycin biosynthetic gene cluster from Streptomyces cinnamoneus
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Location: 1 - 17,083 nt. (total: 17,083 nt).
This entry is originally from NCBI GenBank AJ536588.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000503
Short description cinnamycin biosynthetic gene cluster from Streptomyces cinnamoneus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
AJ536588.1
via Knock-out studies, Enzymatic assays, Heterologous expression
Compounds
  • cinnamycin
Species Streptomyces cinnamoneus [taxonomy]
References
Chemical products information
cinnamycin Evidence:
Copy SMILES
C89H125N25O25S3
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAD60516.1
  • cinorf3
 1 - 346 (-) Cinorf3 protein
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    • CAD60517.1
    • cinorf4
    		 454 - 1026 (+) Cinorf4 protein
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      • CAD60518.1
      		 1109 - 1198 (+) hypothetical protein
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        • CAD60519.1
        • cinorf7
        		 1267 - 1626 (+) Cin orf7 protein
        • Scaffold biosynthesis
        • Other in vivo study
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        • CAD60520.1
        • cinA
        		 1671 - 1907 (+) preprocinnamycin
        • Precursor biosynthesis
        • Other in vivo study
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        • CAD60521.1
        • cinM
        		 2059 - 5325 (+) CinM protein
        • Scaffold biosynthesis
        • Activity assay
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        • CAD60522.1
        • cinX
        		 5340 - 6317 (+) CinX protein
        • Tailoring
        • Activity assay
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        • CAD60523.1
        • cinT
        		 6543 - 7472 (+) CinT protein
        • Transport
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        • CAD60524.1
        • cinH
        		 7469 - 8341 (+) CinH protein
        • Transport
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        • CAD60525.1
        • cinY
        		 8444 - 9466 (+) CinY protein
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          • CAD60526.1
          • cinZ
          		 9545 - 10171 (-) CinZ protein
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            • CAD60527.1
            • cinorf8
            		 10246 - 10665 (+) Cinorf8 protein
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              • CAD60528.1
              • cinorf9
              		 10758 - 11078 (+) Cinorf9 protein
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                • CAD60529.1
                • cinR
                		 11111 - 11761 (-) CinR protein
                • Regulation
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                • CAD60530.1
                • cinK
                		 11758 - 12822 (-) CinK protein
                • Regulation
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                • CAD60531.1
                • cinorf10
                		 13257 - 13754 (+) Cinorf10 protein
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                  • CAD60532.1
                  • cinorf11
                  		 13754 - 14944 (+) Cinorf11 protein
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                    • CAD60533.1
                    • cinR1
                    		 14375 - 15160 (-) CinR1 protein
                    • Regulation
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                    • CAD60534.1
                    • cinorf12
                    		 15381 - 15872 (+) Cinorf12 protein
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                      • CAD60535.1
                      • cinorf13
                      		 15912 - 16496 (+) Cinorf13 protein
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                        • CAD60536.1
                        • cinorf14
                        		 16549 - >17083 (+) Cinorf14 protein
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                          Biosynthesis information
                          Annotation changelog

                          Entry version: 4

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2022-10-07
                          Update chemical activity to schema version 2.11
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 3

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2022-09-15
                          Updated bioactivity data
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 2

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2019-10-16
                          Migrated from v1.4
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          2019-10-16
                          Updated compound(s) information (NPAtlas curation)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 1

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2015-06-12
                          Submitted
                          • (ID: Q466Z24KJDYPHZY2353Y4FFQ)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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