BGC0000516 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000516 (Geobacillus thermodenitrificans)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	lanthipeptide-class-ii,terpene-precursor	1	27,552	High	geobacillin II	ribosomal:RiPP:Lanthipeptide

BGC0000516 - Region 1 - lanthipeptide-class-ii,terpene-precursor

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Location: 1 - 27,552 nt. (total: 27,552 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)
terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Lanthipeptides

Terpene

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 27,553
Label		BGC0000516

Tailoring functions

Lyases: cyclase

G11MC16DRAFT_3401: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Ligases: synthetase

G11MC16DRAFT_3406: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000516.4	2.00	ribosomal	geobacillin II	Geobacillus thermodenitrificans
BGC0000554.4	0.46	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000504.5	0.42	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000527.5	0.39	ribosomal	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0001210.5	0.38	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000502.5	0.35	ribosomal	cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7	Bacillus cereus
BGC0000547.5	0.34	ribosomal	salivaricin 9	Streptococcus salivarius
BGC0001311.5	0.33	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0002005.2	0.31	ribosomal	RaxX	Xanthomonas oryzae pv. oryzae
BGC0000525.5	0.30	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000516.4	1.00	ribosomal	geobacillin II	Geobacillus thermodenitrificans
BGC0000554.4	0.56	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000504.5	0.53	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000527.5	0.52	ribosomal	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0001210.5	0.51	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000502.5	0.49	ribosomal	cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7	Bacillus cereus
BGC0000547.5	0.48	ribosomal	salivaricin 9	Streptococcus salivarius
BGC0001311.5	0.47	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0002005.2	0.46	ribosomal	RaxX	Xanthomonas oryzae pv. oryzae
BGC0000525.5	0.45	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis

Similar known clusters from MIBiG 4.0

Lanthipeptide predictions

Lanthipeptide(s) for G11MC16DRAFT_3401

G11MC16DRAFT_3402

Leader:

MEKQEQTFVSKISEEELKKLAGG

Core:

YTEVSPQSTIVCVSLRICNWSLRFCPSFKVKCPM

Core with dehydrations:

YDhbEVDhaPQDhaDhbIVCysVDhaLRICysNWDhaLRFCysPDhaFKVKCysPM

antiSMASH-DB 4.0 matches for G11MC16DRAFT_3402

100.0%

NZ_PIJH01000018.1:

Lanthipeptides: CV632_RS18055_lanthipeptide

YTEVSPQSTIVCVSLRICNWSLRFCPSFKVKCPM

97.1%

NC_009328.1:

Lanthipeptides: GTNG_RS18990_lanthipeptide

YTEVSPQSTIVCVSLRICNWSLRFCPSFKVKCPM

YTEVSPQSTIVCVSLRICNWSLRFCPSFKV+CPM

YTEVSPQSTIVCVSLRICNWSLRFCPSFKVRCPM

67.6%

NZ_FOHE01000009.1:

Lanthipeptides: BMX40_RS20255_lanthipeptide

EVSPQSTIVCVSLRICNWSLRFCPSFKVKCPM

EV+PQST+VCVSLR+C WS+++CPSFK KC M

EVTPQSTVVCVSLRLCKWSIKYCPSFKRKCWM

with 21 more sequence matches

Only the first 10 are displayed here.

67.6%

NZ_JALANL010000003.1and 3 others:

NZ_MUEI01000003.1 Lanthipeptides: BV582_RS23575_lanthipeptideNZ_NIJN01000002.1 Lanthipeptides: CHCC5027_RS22460_lanthipeptideNZ_NIMF01000037.1 Lanthipeptides: CHCC14814_RS22115_lanthipeptide

Lanthipeptides: MOC63_RS03255_lanthipeptide

EVSPQSTIVCVSLRICNWSLRFCPSFKVKCPM

E++PQST+VCVSLRIC WS+++CPSFK KC M

EITPQSTVVCVSLRICKWSIKYCPSFKRKCWM

64.7%

NZ_CP023481.1and 2 others:

NZ_JALARN010000006.1 Lanthipeptides: MOE03_RS17410_lanthipeptideNZ_JAQCPU010000013.1 Lanthipeptides: PG077_RS20425_lanthipeptide

Lanthipeptides: COP00_RS24795_lanthipeptide

EVSPQSTIVCVSLRICNWSLRFCPSFKVKCPM

E++PQST+VCVSLR+C WS+++CPSFK KC M

EITPQSTVVCVSLRVCKWSIKYCPSFKRKCWM

64.7%

NZ_JALAJI010000006.1and 3 others:

NZ_JALAOO010000008.1 Lanthipeptides: MOC69_RS16910_lanthipeptideNZ_JALAXE010000008.1 Lanthipeptides: MOF11_RS14910_lanthipeptideNZ_JALAXI010000013.1 Lanthipeptides: MOE73_RS14185_lanthipeptide

Lanthipeptides: MOB90_RS08905_lanthipeptide

EVSPQSTIVCVSLRICNWSLRFCPSFKVKCPM

E++PQST+VCVSLR+C WS+++CPSFK KC M

EITPQSTVVCVSLRLCKWSIKYCPSFKKKCLM

42.9%

NZ_CP039297.1and 4 others:

NZ_CP040378.1 Lanthipeptides: D1120_RS00435_lanthipeptideNZ_CP040672.1 Lanthipeptides: FGE23_RS05605_lanthipeptideNZ_CP059318.1 Lanthipeptides: HZT45_RS00565_lanthipeptideNZ_CP087137.1 Lanthipeptides: LOK79_RS00585_lanthipeptide

Lanthipeptides: E4T61_RS00570_lanthipeptide

TEVSPQSTIVCVSLRICNWSLRFCPSFKVKC

T VSP T+V +R+ SL+ CP+FK+KC

TPVSPAPTVV---IRV---SLKVCPTFKIKC

41.7%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06300_lanthipeptide

Lanthipeptides: EG886_RS06300_lanthipeptide

EVSPQSTIVC-VSLRIC-NWSLRFCPS

EV PQS VC V+L +C SL FCP+

EVRPQSGPVCAVTLAVCVPVSLAFCPT

32.4%

NZ_WIXN01000006.1and 1 other:

NZ_WIXN01000006.1 Lanthipeptides: GHD25_RS06900_lanthipeptide

Lanthipeptides: GHD25_RS06900_lanthipeptide

STIVCVSLRICNWSLRFCPSFKVKCP

+TI+ VSL +C + C SF CP

TTIIPVSLAVCPTTT--CRSFSSPCP

29.4%

NC_018499.1and 5 others:

NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide

Lanthipeptides: BCK_RS27845_lanthipeptide

EVSPQS-TIVCVSLRIC

E +P + TIV VSL IC

ETTPATPTIVAVSLGIC

29.4%

NZ_CP102973.1and 1 other:

NZ_FQQG01000014.1 Lanthipeptides: BT790_RS14420_lanthipeptide

Lanthipeptides: NW963_RS14100_lanthipeptide

EVSPQSTIVCVSLRICNWSLRFCPSFKVKC

+V+P+ST VC + S++ + K KC

DVTPESTTVCAAFASFAGSIQLVKTLKSKC

26.5%

NZ_JQBU01000033.1and 1 other:

NZ_JQBV01000009.1 Lanthipeptides: IV76_RS12120_lanthipeptide

Lanthipeptides: IV75_RS14620_lanthipeptide

EVSPQSTIVCVSLRICNWSLRFCPSFKVKC

+V P+ST +C S+ + K KC

DVMPESTPICAGFATLMSSIGLVKTIKGKC

23.5%

NZ_CP067069.1and 13 others:

NZ_CP085413.1 Lanthipeptides: LIS80_RS25350_lanthipeptideNZ_JH792105.1 Lanthipeptides: II5_RS26960_lanthipeptideNZ_JH792240.1 Lanthipeptides: IIK_RS26240_lanthipeptideNZ_MOOT01000061.1 Lanthipeptides: BK765_RS23985_lanthipeptideNZ_NTUF01000024.1 Lanthipeptides: CN379_RS26680_lanthipeptideNZ_NVCZ01000001.1 Lanthipeptides: COK75_RS01180_lanthipeptideNZ_NVDK01000008.1 Lanthipeptides: COK95_RS05665_lanthipeptideNZ_NVEA01000001.1 Lanthipeptides: COL15_RS00010_lanthipeptideNZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08190_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20675_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19560_lanthipeptideNZ_WBPE01000025.1 Lanthipeptides: F8161_RS14435_lanthipeptideNZ_WBPK01000016.1 Lanthipeptides: F8167_RS15685_lanthipeptide

Lanthipeptides: JCR32_RS24620_lanthipeptide

TEVSPQSTIVCVSLRI-CNWSLRFC

++V P++T +CV + I S++ C

SDVQPETTPLCVGVIIGITASIKIC

MIBiG 4.0 matches for G11MC16DRAFT_3402

14.7%

BGC0000553.3 (SSGG_RS09925):

Lanthipeptide: SRO15-2212

VSLRICNWS

VSL +C +S

VSLLVCEYS

14.7%

BGC0001155.5 (AGY49587.1):

Thiopeptide: GE2270

CNWSLRFCPS

CN FC S

CNCVCGFCCS

allorf_01594_01794

Leader:

MSFLSTLLAS

Core:

RTSSFFYTILNLFENGAGSVASMSIMSIKFLATLFHLLNCPATLERAFLSPLELLS

Core with dehydrations:

RDhbDhaDhaFFYDhbILNLFENGAGDhaVADhaMDhaIMDhaIKFLADhbLFHLLNCysPADhbLERAFLDhaPLELLDha

antiSMASH-DB 4.0 matches for allorf_01594_01794

12.5%

NZ_KB217478.1:

Lanthipeptides: allorf_3684331_3684489_lanthipeptide

LATLFHLLNCPATLERA

+ TL+ L+NCP +R+

VPTLYTLINCPGVQQRS

10.7%

NZ_AP026073.1and 13 others:

NZ_BBUY01000020.1 Lanthipeptides: AZE13_RS34600_lanthipeptideNZ_BMUN01000013.1 Lanthipeptides: IE238_RS22260_lanthipeptideNZ_CP009754.1 Lanthipeptides: NI25_RS06465_lanthipeptideNZ_CP015588.1 Lanthipeptides: A7J05_RS07195_lanthipeptideNZ_CP023697.1 Lanthipeptides: CP972_RS03610_lanthipeptideNZ_CP029192.1 Lanthipeptides: DEJ48_RS36690_lanthipeptideNZ_CP029192.1 Lanthipeptides: DEJ48_RS36690_lanthipeptideNZ_CP031194.1 Lanthipeptides: DVK44_RS04655_lanthipeptideNZ_CP039123.1 Lanthipeptides: E5N77_RS29900_lanthipeptideNZ_CP042324.1 Lanthipeptides: FQ762_RS35785_lanthipeptideNZ_CP042324.1 Lanthipeptides: FQ762_RS35780_lanthipeptideNZ_CP116257.1 Lanthipeptides: BJ961_RS11895_lanthipeptideNZ_ML123127.1 Lanthipeptides: EES47_RS19530_lanthipeptide

Lanthipeptides: HEK616_RS04845_lanthipeptide

LNLFENGAGSVAS

+NL ++G GS S

INLTDDGCGSTCS

10.7%

NZ_BBOK01000007.1and 3 others:

NZ_CP019458.1 Lanthipeptides: BV401_RS15675_lanthipeptideNZ_CP065050.1 Lanthipeptides: I1A49_RS15455_lanthipeptideNZ_LJIW01000001.1 Lanthipeptides: SMF913_RS16250_lanthipeptide

Lanthipeptides: APK71_RS35805_lanthipeptide

ILNLFENGAGSVAS

++NL ++G GS S

LINLTDDGCGSTCS

allorf_02128_02250

Leader:

MRKKVNTQASFSLNSCELLKLKAG

Core:

NAKKKTRQKELVQRLC

Core with dehydrations:

NAKKKDhbRQKELVQRLCys

antiSMASH-DB 4.0 matches for allorf_02128_02250

22.7%

NZ_AP018222.1:

Lanthipeptides: allorf_6074493_6074612_lanthipeptide

KTRQKELVQRLC

+ R+K QR C

RGREKSFTQRYC

allorf_02560_02667

Leader:

MLRRIKTRRELMSITES

Core:

LKRAKRFVELCPTRGKFA

Core with dehydrations:

LKRAKRFVELCysPDhbRGKFA

allorf_05576_05641

Leader:

MLHSRAGS

Core:

MRLALELALSCCS

Core with dehydrations:

MRLALELALDhaCysCysDha

antiSMASH-DB 4.0 matches for allorf_05576_05641

100.0%

NC_009328.1:

Lanthipeptides: allorf_2183040_2183105_lanthipeptide

MRLALELALSCCS

allorf_17689_17868

Leader:

MVWSPLPYRKIRIFCTLYFLYFPTAFYVNISSTTCGEEPKNSLFA

Core:

IFCYFHQSQNMLVG

Core with dehydrations:

IFCysYFHQDhaQNMLVG

antiSMASH-DB 4.0 matches for allorf_17689_17868

100.0%

NC_009328.1:

Lanthipeptides: allorf_2195153_2195332_lanthipeptide

IFCYFHQSQNMLVG

22.6%

NZ_CP006269.1:

Lanthipeptides: allorf_1795731_1795883_lanthipeptide

FCY-----FHQSQNMLVG

+CY Q QN+L+G

WCYSVAMRVAQQQNLLIG

allorf_17938_18039

Leader:

MKRNEKKENAG

Core:

FSNFLFPNNVRYVLSACNAQQK

Core with dehydrations:

FDhaNFLFPNNVRYVLDhaACysNAQQK

antiSMASH-DB 4.0 matches for allorf_17938_18039

29.2%

NZ_SHKR01000011.1:

Lanthipeptides: allorf_1651888_1652001_lanthipeptide

SNFLFPNNVRYVLSACN

+ L+P YVLS+C

TGGLWPVAEVYVLSSCR

allorf_18122_18280

Leader:

MLHLWHDIQHLLSRDLPSKCGNGRLSTMGGA

Core:

ILHWNIHSGGGSYAKTPLHDC

Core with dehydrations:

ILHWNIHDhaGGGDhaYAKDhbPLHDCys

antiSMASH-DB 4.0 matches for allorf_18122_18280

28.6%

NZ_CP016279.1:

Lanthipeptides: allorf_04627901_04628032_lanthipeptide

WNIHSGGGSYAKTPLHDC

W+ H G S KT L C

WSAHGGPDSVVKTGLGGC

25.7%

NZ_JAKVDC010000003.1:

Lanthipeptides: MKN04_RS09455_lanthipeptide

WN--IHSGGGSYAKTPLHDC

WN I GGG+ +KT + C

WNCSIGCGGGNTSKTCVETC

20.8%

NZ_JANZKX010000002.1:

Lanthipeptides: allorf_602154_602312_lanthipeptide

IHSGGGSYAKTPLHDC

H G + +TP++ C

FHVGRQALRRTPVNPC

allorf_18754_18981

Leader:

MFINPSNIFAM

Core:

YPKAKANDRRNVAWKLGFIGICFVLVLLCVPSQKHSQNEQKKSFRAFCRLIRMGKWKGRITRSS

Core with dehydrations:

YPKAKANDRRNVAWKLGFIGICysFVLVLLCysVPDhaQKHDhaQNEQKKDhaFRAFCysRLIRMGKWKGRIDhbRDhaDha

antiSMASH-DB 4.0 matches for allorf_18754_18981

10.9%

NZ_CP022098.1:

Lanthipeptides: CYFUS_RS06215_lanthipeptide

FCRLIRMGKWKG

FCR+IR W+G

FCRVIRESAWRG

9.4%

NZ_CP023466.1and 2 others:

NZ_JHVT01000005.1 Lanthipeptides: allorf_209755_209919_lanthipeptideNZ_KB906329.1 Lanthipeptides: allorf_164860_165024_lanthipeptide

Lanthipeptides: allorf_0897333_0897497_lanthipeptide

FVLVLLCVPSQKHSQN

F++VL C P ++H ++

FIVVLFCYPDERHYKS

MIBiG 4.0 matches for allorf_18754_18981

12.5%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

NVAWKLGFIGICFVLVLLCVPS

N++ +LG G L + C+PS

NISCRLGNKGAYCTLTVECMPS

allorf_19061_19195

Leader:

MIDASTSFG

Core:

DEPEYNIIANMLHSTISDKTRRGVSSSFCALFYMI

Core with dehydrations:

DEPEYNIIANMLHDhaDhbIDhaDKDhbRRGVDhaDhaDhaFCysALFYMI

antiSMASH-DB 4.0 matches for allorf_19061_19195

100.0%

NC_009328.1:

Lanthipeptides: allorf_2196525_2196659_lanthipeptide

DEPEYNIIANMLHSTISDKTRRGVSSSFCALFYMI

14.3%

NZ_CP028286.1:

Lanthipeptides: allorf_098636_098806_lanthipeptide

NIIANMLHSTISDKTRRGV

N++ + +STI+ + +G+

NVLFTVCYSTIASRKNKGI

MIBiG 4.0 matches for allorf_19061_19195

13.5%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

GVSSSFC

GVS++FC

GVSAAFC

allorf_20333_20479

Leader:

MVSSIIRRTPRTPNGFPFRSFLFDFQLLRNHEQLHIRGA

Core:

KRSCKISSQ

Core with dehydrations:

KRDhaCysKIDhaDhaQ

allorf_20391_20582

Leader:

MRRSWKSKRNERNGKPFG

Core:

VRGVRRMIEETIILFVFLFLVIVIFLYFFFCCYSGFFSDFTNTIT

Core with dehydrations:

VRGVRRMIEEDhbIILFVFLFLVIVIFLYFFFCysCysYDhaGFFDhaDFDhbNDhbIDhb

allorf_20678_20767

Leader:

MKKNLILLKMLYT

Core:

STICNIFWYILNMVKK

Core with dehydrations:

DhaDhbICysNIFWYILNMVKK

antiSMASH-DB 4.0 matches for allorf_20678_20767

13.9%

NZ_JAPVBQ010000001.1:

Lanthipeptides: O2V63_RS05740_lanthipeptide

ICNIFW

IC IFW

ICGIFW

6.2%

NZ_CP116936.1:

Lanthipeptides: allorf_2860588_2860818_lanthipeptide

ICNIFWY

IC++ WY

ICSLLWY

allorf_21999_22118

Leader:

MADRIDSRSHFVFFG

Core:

LLPREIHVVFPYRLGLASSHQRCM

Core with dehydrations:

LLPREIHVVFPYRLGLADhaDhaHQRCysM

allorf_22204_22362

Leader:

MTPNLFRKRSKELFA

Core:

TSPSVYIPILFKCFSIRLPMPQISRNGTGHNFFETSS

Core with dehydrations:

DhbDhaPDhaVYIPILFKCysFDhaIRLPMPQIDhaRNGDhbGHNFFEDhbDhaDha

antiSMASH-DB 4.0 matches for allorf_22204_22362

16.2%

NZ_CP095481.1:

Lanthipeptides: allorf_08453940_08454071_lanthipeptide

GTGHNFFETSS

G GH ET+S

GCGHELLETNS

11.5%

NZ_LMGS01000001.1:

Lanthipeptides: allorf_1211017_1211229_lanthipeptide

FKCFSIRLPMPQISRNGT

++C S+R P P +G+

WRCGSLRSPHPTWGYSGS

allorf_22228_22398

Leader:

MASSIAGNLGHWQPNGETFEQYGNVYAWRRSKQFFGS

Core:

FTKEIWRHRRTALLSCLGH

Core with dehydrations:

FDhbKEIWRHRRDhbALLDhaCysLGH

antiSMASH-DB 4.0 matches for allorf_22228_22398

26.3%

NZ_CP045142.1:

Lanthipeptides: allorf_1408221_1408304_lanthipeptide

WRHRRTALL

WR+RR+A +

WRYRRSAPI

allorf_22717_22839

Leader:

MGPNLSRIASIALA

Core:

RARSFVLSSKRDNCKLSSSIKFPRDT

Core with dehydrations:

RARDhaFVLDhaDhaKRDNCysKLDhaDhaDhaIKFPRDDhb

antiSMASH-DB 4.0 matches for allorf_22717_22839

18.8%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06325_lanthipeptide

Lanthipeptides: EG886_RS06325_lanthipeptide

SKRDNCKLSSSIKFPRDT

S+R C++ SSIKF T

SRRRICEIVSSIKFKWKT

11.1%

NZ_JADG01000011.1:

Lanthipeptides: allorf_410874_411095_lanthipeptide

ARSFVLSSKRDNCKLSSS

R F + +R C+LSS+

GRGFYRAQRRLPCELSSN

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Detailed terpene predictions

Product predictions:

Class	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor	FPP	C15	acyclic	PP
diterpene precursor	GGPP	C20	acyclic	PP
sesterterpene precursor	GFPP	C25	acyclic	PP
triterpene precursor	HPP	C30	acyclic	PP

Genes with terpene domains:

G11MC16DRAFT_3406: PT_FPPS_like

Domain 1 (58 - 307): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

Lanthipeptides

Terpene

Core peptide predictions

G11MC16DRAFT_3402 - Class II

Cleavage pHMM score: 2.00

RODEO score: 0

Monoisotopic mass: 3794.9 Da

Molecular weight: 3797.5 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3815.5 Da N = 1; 3833.6 Da N = 2; 3851.6 Da N = 3

allorf_01594_01794 - Class II

Cleavage pHMM score: -3.70

RODEO score: 0

Monoisotopic mass: 5965.2 Da

Molecular weight: 5969.0 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 5987.0 Da N = 1; 6005.0 Da N = 2; 6023.0 Da N = 3; 6041.0 Da N = 4; 6059.1 Da N = 5; 6077.1 Da N = 6; 6095.1 Da N = 7; 6113.1 Da N = 8; 6131.1 Da N = 9; 6149.2 Da N = 10; 6167.2 Da N = 11

allorf_02128_02250 - Class II

Cleavage pHMM score: -4.30

RODEO score: 0

Monoisotopic mass: 1924.1 Da

Molecular weight: 1925.3 Da

Number of bridges: 1

allorf_02560_02667 - Class II

Cleavage pHMM score: -6.80

RODEO score: 0

Monoisotopic mass: 2101.2 Da

Molecular weight: 2102.5 Da

Number of bridges: 1

allorf_05576_05641 - Class II

Cleavage pHMM score: -5.70

RODEO score: 0

Monoisotopic mass: 1372.7 Da

Molecular weight: 1373.7 Da

Number of bridges: 2

allorf_17689_17868 - Class II

Cleavage pHMM score: -3.30

RODEO score: 0

Monoisotopic mass: 1667.8 Da

Molecular weight: 1668.9 Da

Number of bridges: 1

allorf_17938_18039 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 2523.3 Da

Molecular weight: 2524.8 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 2542.9 Da N = 1

allorf_18122_18280 - Class II

Cleavage pHMM score: -1.50

RODEO score: 0

Monoisotopic mass: 2251.1 Da

Molecular weight: 2252.5 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 2270.5 Da N = 1; 2288.5 Da N = 2

allorf_18754_18981 - Class II

Cleavage pHMM score: -5.80

RODEO score: 0

Monoisotopic mass: 7355.1 Da

Molecular weight: 7359.7 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 7377.7 Da N = 1; 7395.7 Da N = 2; 7413.8 Da N = 3

allorf_19061_19195 - Class II

Cleavage pHMM score: -7.30

RODEO score: 0

Monoisotopic mass: 3881.9 Da

Molecular weight: 3884.4 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 3902.4 Da N = 1; 3920.4 Da N = 2; 3938.4 Da N = 3; 3956.5 Da N = 4; 3974.5 Da N = 5; 3992.5 Da N = 6

allorf_20333_20479 - Class II

Cleavage pHMM score: -2.40

RODEO score: 0

Monoisotopic mass: 981.5 Da

Molecular weight: 982.1 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1000.2 Da N = 1; 1018.2 Da N = 2

allorf_20391_20582 - Class II

Cleavage pHMM score: -6.30

RODEO score: 0

Monoisotopic mass: 5317.8 Da

Molecular weight: 5321.3 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 5339.4 Da N = 1; 5357.4 Da N = 2; 5375.4 Da N = 3; 5393.4 Da N = 4

allorf_20678_20767 - Class II

Cleavage pHMM score: -7.20

RODEO score: 0

Monoisotopic mass: 1936.0 Da

Molecular weight: 1937.4 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1955.4 Da N = 1

allorf_21999_22118 - Class II

Cleavage pHMM score: -6.90

RODEO score: 0

Monoisotopic mass: 2785.5 Da

Molecular weight: 2787.3 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 2805.3 Da N = 1

allorf_22204_22362 - Class II

Cleavage pHMM score: -6.30

RODEO score: 0

Monoisotopic mass: 4009.1 Da

Molecular weight: 4011.6 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 4029.6 Da N = 1; 4047.6 Da N = 2; 4065.6 Da N = 3; 4083.7 Da N = 4; 4101.7 Da N = 5; 4119.7 Da N = 6; 4137.7 Da N = 7; 4155.7 Da N = 8

allorf_22228_22398 - Class II

Cleavage pHMM score: -6.10

RODEO score: 0

Monoisotopic mass: 2269.2 Da

Molecular weight: 2270.6 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 2288.7 Da N = 1; 2306.7 Da N = 2

allorf_22717_22839 - Class II

Cleavage pHMM score: -7.30

RODEO score: 0

Monoisotopic mass: 2871.6 Da

Molecular weight: 2873.3 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 2891.3 Da N = 1; 2909.3 Da N = 2; 2927.3 Da N = 3; 2945.3 Da N = 4; 2963.4 Da N = 5; 2981.4 Da N = 6

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate