BGC0000517: haloduracin β biosynthetic gene cluster from Bacillus halodurans C-125
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Location: 476,922 - 486,037 nt. (total: 9,116 nt).
This entry is originally from NCBI GenBank BA000004.3.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000517
Short description haloduracin β biosynthetic gene cluster from Bacillus halodurans C-125
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Remarks "The lantibiotic synthetases complete dehydration and cyclization so reaction type was marked as other. "
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
BA000004.3
476922 - 486037
via Enzymatic assays, Heterologous expression, Gene expression correlated with compound production
Compounds
  • haloduracin β
  • haloduracin α
Species Bacillus halodurans C-125 [taxonomy]
References
Chemical products information
haloduracin β Evidence:
(no structure information available)
C103H155N27O27S4
haloduracin α Evidence:
(no structure information available)
C130H196N36O37S6
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAB04170.1
  • BH0451
 476922 - 479096 (-) lantibiotic haloduracin protease and transporter
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    • BAB04171.1
    • BH0452
    		 479086 - 482058 (-) Class II lantibiotic synthetase
    • Scaffold biosynthesis
    • Other in vivo study Activity assay
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    • BAB04172.1
    • BH0453
    		 482191 - 482388 (-) lantibiotic haloduracin precursor
    • Precursor biosynthesis
    • Activity assay
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    • BAB04173.1
    • BH0454
    		 482580 - 482789 (+) lantibiotic haloduracin precursor
    • Precursor biosynthesis
    • Activity assay
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    • BAB04174.1
    • BH0455
    		 482858 - 486037 (+) Class II lantibiotic synthetase
    • Scaffold biosynthesis
    • Other in vivo study Activity assay
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    Biosynthesis information
    Annotation changelog

    Entry version: 3

    Date
    Changes
    Submitters
    Reviewers
    2022-10-07
    Update chemical activity to schema version 2.11
    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

    Entry version: 2

    Date
    Changes
    Submitters
    Reviewers
    2019-10-16
    Migrated from v1.4
    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

    Entry version: 1

    Date
    Changes
    Submitters
    Reviewers
    2015-06-12
    Submitted
    • (ID: ZMZXFLPDGFEHMQPX76IB4OQ3)
    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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