Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000523.1:
Cluster 1RiPP115996

BGC0000523, lactocin S biosynthetic gene cluster from Lactobacillus sakei. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: lactocin S

Class-specific details

Biosynthetic class(es):
RiPP
RiPP subclass:
Lanthipeptide

Gene cluster description

lactocin S (BGC0000523). Gene Cluster 1. Biosynthetic class = RiPP. GenBank Z54312. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

No core peptides found.

Literature references

1. Skaugen M, Nes IF. (1994) Transposition in Lactobacillus sake and its abolition of lactocin S production by insertion of IS1163, a new member of the IS3 family. Appl Environ Microbiol 60(8):2818-25.
2. Skaugen M et al. (1994) In vivo conversion of L-serine to D-alanine in a ribosomally synthesized polypeptide. J Biol Chem 269(44):27183-5.
3. Skaugen M et al. (1997) Organization and expression of a gene cluster involved in the biosynthesis of the lantibiotic lactocin S. Mol Gen Genet 253(6):674-86.
4. Qvarnstrom Y, Swedberg G. (2000) Additive effects of a two-amino-acid insertion and a single-amino-acid substitution in dihydropteroate synthase for the development of sulphonamide-resistant Neisseria meningitidis. Microbiology 146 ( Pt 5):1151-6. doi: 10.1099/00221287-146-5-1151.
5. Skaugen M et al. (2002) Identification, characterization, and expression of a second, bicistronic, operon involved in the production of lactocin S in Lactobacillus sakei L45. Appl Environ Microbiol 68(2):720-7.