BGC0000525 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000525 (Bacillus licheniformis)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	lanthipeptide-class-ii	1	3,837	High	lichenicidin VK21 A1/lichenicidin VK21 A2	ribosomal:RiPP:Lanthipeptide

BGC0000525 - Region 1 - lanthipeptide-class-ii

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Location: 1 - 3,837 nt. (total: 3,837 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 3,838
Label		BGC0000525

Tailoring functions

Lyases: cyclase

LchM1: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000525.5	1.00	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000517.4	0.54	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000528.5	0.45	ribosomal	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000554.4	0.45	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000500.5	0.44	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000504.5	0.44	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0001210.5	0.43	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0001311.5	0.41	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0001391.3	0.41	ribosomal	thusin	Bacillus thuringiensis serovar rongseni
BGC0000527.5	0.40	ribosomal	mersacidin	Bacillus sp. HIL-Y85/54728

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000525.5	1.00	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000517.4	0.54	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000528.5	0.45	ribosomal	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000554.4	0.45	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000500.5	0.44	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000504.5	0.44	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0001210.5	0.43	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0001311.5	0.41	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0001391.3	0.41	ribosomal	thusin	Bacillus thuringiensis serovar rongseni
BGC0000527.5	0.40	ribosomal	mersacidin	Bacillus sp. HIL-Y85/54728

Similar known clusters from MIBiG 4.0

Lanthipeptide predictions

Lanthipeptide(s) for LchM1

lchA2

Leader:

MKTMKNSAAREAFKGANHPAGMVSEEELKALVGG

Core:

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

Core with dehydrations:

NDVNPEDhbDhbPADhbDhbDhaDhaWDhbCysIDhbAGVDhbVDhaADhaLCysPDhbDhbKCysDhbDhaRCys

antiSMASH-DB 4.0 matches for lchA2

100.0%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide

Lanthipeptides: BLI_RS20290_lanthipeptide

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

87.2%

NZ_CP009288.1and 3 others:

NZ_CP009288.1 Lanthipeptides: PDUR_RS29295_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptide

Lanthipeptides: PDUR_RS29295_lanthipeptide

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

DVNPETT TTSSWTCITAGVTVSASLCPTTKCTS+C

GDVNPETTILTTSSWTCITAGVTVSASLCPTTKCTSQC

71.1%

NZ_CM000721.1and 9 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide

Lanthipeptides: BCERE0010_RS29355_lanthipeptide

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

DVNPETTPAT T I A + V+ASLCPTTKCTSRC

GDVNPETTPAT---PTIIGATIAVTASLCPTTKCTSRC

with 133 more sequence matches

Only the first 10 are displayed here.

69.2%

NZ_CP009280.1and 1 other:

NZ_CP009280.1 Lanthipeptides: P40081_RS37160_lanthipeptide

Lanthipeptides: P40081_RS37160_lanthipeptide

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

DVNPETTP TTSSW C+ V +SA+LCPTTKCTS+C

GDVNPETTPLTTSSWPCVIGAVDISANLCPTTKCTSKC

60.5%

NZ_CP015591.1and 15 others:

NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide

Lanthipeptides: A7A70_RS27550_lanthipeptide

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

DVNPETTPAT T + A + + S+CPTTKCTSRC

GDVNPETTPAT---PTIVEATIAATVSICPTTKCTSRC

60.5%

NZ_CP085411.1and 1 other:

NZ_CP085411.1 Lanthipeptides: LIT28_RS29915_lanthipeptide

Lanthipeptides: LIT28_RS29915_lanthipeptide

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

DVNPETTP T + T + G T+S +CPTTKCTSRC

GDVNPETTPTTATVTT-VLVGATIS--VCPTTKCTSRC

60.5%

NZ_QNUC01000031.1and 1 other:

NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23045_lanthipeptide

Lanthipeptides: DN396_RS23045_lanthipeptide

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

DVNPETTP T + T + G T+S +CPTTKCTSRC

GDVNPETTPTTATVTT-VLVGATIS--ICPTTKCTSRC

57.9%

NC_018499.1and 5 others:

NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide

Lanthipeptides: BCK_RS27845_lanthipeptide

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

DVNPETTPAT + V VS +CPTTKCTS+C

GDVNPETTPATPTI-------VAVSLGICPTTKCTSKC

57.9%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

DV+PETTPAT T V +S LCPTTKCTS+C

GDVSPETTPATP------TIVVAISVGLCPTTKCTSKC

57.9%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

DV+PETTPAT T V +S LCPTTKCTS+C

GDVSPETTPATP------TIVVGISVGLCPTTKCTSKC

55.3%

NZ_CP006058.1and 25 others:

NZ_CP006058.1 Lanthipeptides: BAMY6639_RS19790_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptideNZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptideNZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptide

Lanthipeptides: BAMY6639_RS19790_lanthipeptide

DVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

DV P TTP SS C GV V+A+ CP+TKCTS C

DVTPHTTP---SSLPC---GVFVTAAFCPSTKCTSSC

55.3%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27165_lanthipeptide

Lanthipeptides: EXW52_RS27165_lanthipeptide

DVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

DVNPET PAT T I A +T LCP+ CTSRC

DVNPETIPATA---TPILANLT--KELCPSIPCTSRC

52.6%

NZ_CP036019.1and 7 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27190_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide

Lanthipeptides: EXW52_RS27190_lanthipeptide

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

DV+PETTPAT T V +S LCPT +CTS+C

GDVSPETTPATP------TIVVAISVGLCPTNRCTSKC

MIBiG 4.0 matches for lchA2

55.3%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

TTPATTS---SWTCITAGVTV--SASLCPTTKCTSRC

T PA T I AGV V SA+ CPTTKCTSRC

TDPAVTGLILGIVAIQAGVAVGVSAAFCPTTKCTSRC

23.7%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

LCPTTKCTSRC

CPTTKCTS+C

FCPTTKCTSKC

lchA1

Leader:

MSKKEMILSWKNPMYRTESSYHPAGNILKELQEEEQHSIAGG

Core:

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

Core with dehydrations:

DhbIDhbLDhaDhbCysAILDhaKPLGNNGYLCysDhbVDhbKECysMPDhaCysN

antiSMASH-DB 4.0 matches for lchA1

100.0%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20295_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptide

Lanthipeptides: BLI_RS20295_lanthipeptide

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

58.3%

NZ_CP009288.1and 3 others:

NZ_CP009288.1 Lanthipeptides: PDUR_RS25150_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01580_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01580_lanthipeptide

Lanthipeptides: PDUR_RS25150_lanthipeptide

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

T+T ST ++S LGNNG++CT TKECMPSCN

TLTTSTSILISMTLGNNGWVCTATKECMPSCN

56.2%

NZ_CP015591.1and 19 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27560_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29375_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29370_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29365_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29955_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29950_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29945_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29955_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29950_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29945_lanthipeptideNZ_JACYOF010000027.1 Lanthipeptides: IGI01_RS29005_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29780_lanthipeptideNZ_NVJC01000007.1 Lanthipeptides: COM38_RS07400_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23035_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23030_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23025_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23035_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23030_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23025_lanthipeptide

Lanthipeptides: A7A70_RS27565_lanthipeptide

LSKPLGNNGYLCTVTKECMPSCN

LS LGNNG CT+TKECMPSCN

LSSWLGNNGGYCTLTKECMPSCN

with 103 more sequence matches

Only the first 10 are displayed here.

56.2%

NZ_CP050134.2and 3 others:

NZ_EQ973330.1 Lanthipeptides: CORMATOL_RS10565_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptide

Lanthipeptides: HBA49_RS00770_lanthipeptide

LSKPLGNNGYLCTVTKECMPSCN

LS+ LGNNG CT+TKECMPSCN

LSRLLGNNGRWCTITKECMPSCN

53.1%

NC_018499.1and 10 others:

NC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27860_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptideNZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25275_lanthipeptideNZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25270_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27570_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27565_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27560_lanthipeptide

Lanthipeptides: BCK_RS27860_lanthipeptide

LSKPLGNNGYLCTVTKECMPSCN

LS LGN G CT+TKECMPSCN

LSSWLGNKGGYCTLTKECMPSCN

52.8%

NZ_CP009280.1and 1 other:

NZ_CP009280.1 Lanthipeptides: P40081_RS01820_lanthipeptide

Lanthipeptides: P40081_RS01820_lanthipeptide

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

T+T ST +S+ LGN+G++CT +KECMPSCN

TLTTSTSIFISRGLGNDGWVCTWSKECMPSCN

50.0%

NZ_CP036019.1and 9 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27210_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27215_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27210_lanthipeptideNZ_JANIOB010000033.1 Lanthipeptides: NQ113_RS28005_lanthipeptideNZ_JH791925.1 Lanthipeptides: IE3_RS28545_lanthipeptideNZ_NUML01000015.1 Lanthipeptides: COD66_RS20150_lanthipeptideNZ_NUML01000015.1 Lanthipeptides: COD66_RS20145_lanthipeptideNZ_NUVR01000040.1 Lanthipeptides: COI88_RS26655_lanthipeptideNZ_NUVR01000040.1 Lanthipeptides: COI88_RS26650_lanthipeptide

Lanthipeptides: EXW52_RS27215_lanthipeptide

LSKPLGNNGYLCTVTKECMPSCN

LS LGN G CT+TKECM SCN

LSSWLGNKGGYCTLTKECMSSCN

50.0%

NZ_CP042598.1and 2 others:

NZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11615_lanthipeptideNZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11615_lanthipeptide

Lanthipeptides: FUT28_RS13825_lanthipeptide

LSKPLGNNGYLCTVTKECMPSCN

LS LGN G CT TKECMPSCN

LSDYLGNTGGWCTATKECMPSCN

50.0%

NZ_CP084530.1and 1 other:

NZ_CP084530.1 Lanthipeptides: LDO05_RS02075_lanthipeptide

Lanthipeptides: LDO05_RS02075_lanthipeptide

LSKPLGNNGYLCTVTKECMPSCN

LS LGNNG CT+TKEC SCN

LSNYLGNNGGWCTLTKECQRSCN

50.0%

NZ_JADPDT010000005.1and 1 other:

NZ_JADPDT010000005.1 Lanthipeptides: I4V19_RS09885_lanthipeptide

Lanthipeptides: I4V19_RS09885_lanthipeptide

LSKPLGNNGYLCTVTKECMPSCN

LS LGN G CT TKECMPSCN

LSDFLGNTGGWCTATKECMPSCN

50.0%

NZ_LT630004.1:

Lanthipeptides: BQ5796_RS17475_lanthipeptide

LSKPLGNNGYLCTVTKECMPSCN

LS LGN+G CT+T ECMPSCN

LSSLLGNDGKFCTLTVECMPSCN

46.9%

NC_002570.2and 3 others:

NC_002570.2 Lanthipeptides: AYT26_RS02480_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide

Lanthipeptides: AYT26_RS02480_lanthipeptide

LSKPLGNNGYLCTVTKECMPSCN

+S LGN G CT+T ECMPSCN

ISCRLGNKGAYCTLTVECMPSCN

46.9%

NZ_AKXV01000031.1and 4 others:

NZ_AKXV01000031.1 Lanthipeptides: Y19_RS0109895_lanthipeptideNZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13545_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide

Lanthipeptides: Y19_RS0109895_lanthipeptide

LSKPLGNNGYLCTVTKECMPSCN

LS LGN G CT+TKEC P+CN

LSDFLGNQGGWCTLTKECQPNCN

MIBiG 4.0 matches for lchA1

50.0%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

LSKPLGNNGYLCTVTKECMPSCN

LS LGNNG CT+TKEC P+CN

LSNALGNNGGWCTLTKECQPNCN

46.9%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

LSKPLGNNGYLCTVTKECMPSCN

+S LGN G CT+T ECMPSCN

ISCRLGNKGAYCTLTVECMPSCN

20.5%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTVTKECMPSCN

CT++KEC P+CN

CTLSKECQPNCN

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

lchA2 - Class II

Cleavage pHMM score: 1.50

RODEO score: 0

Monoisotopic mass: 3632.8 Da

Molecular weight: 3635.0 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3653.0 Da N = 1; 3671.1 Da N = 2; 3689.1 Da N = 3; 3707.1 Da N = 4; 3725.1 Da N = 5; 3743.1 Da N = 6; 3761.2 Da N = 7; 3779.2 Da N = 8; 3797.2 Da N = 9; 3815.2 Da N = 10; 3833.2 Da N = 11

lchA1 - Class II

Cleavage pHMM score: 3.30

RODEO score: 0

Monoisotopic mass: 3230.6 Da

Molecular weight: 3232.8 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3250.8 Da N = 1; 3268.8 Da N = 2; 3286.9 Da N = 3; 3304.9 Da N = 4