Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000541.1:
Cluster 1RiPP19113

BGC0000541, paenicidin A biosynthetic gene cluster from Paenibacillus polymyxa. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: paenicidin A

Class-specific details

Biosynthetic class(es):
RiPP
RiPP subclass:
Lanthipeptide

Gene cluster description

paenicidin A (BGC0000541). Gene Cluster 1. Biosynthetic class = RiPP. GenBank JX679672. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

paeA leader / core peptide, putative Class I
MAENLFDLDIQVNKSQGSVEPQ - VLDhaIVACDhaDhaGCGDhaGKDhbAADhaCVEDhbCGNRCFDhbNVGDhaLC

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Homologous known gene clusters

Literature references

1. Lohans CT et al. (2012) Structural characterization of the highly cyclized lantibiotic paenicidin A via a partial desulfurization/reduction strategy. J Am Chem Soc 134(48):19540-3. doi: 10.1021/ja3089229. Epub 2012 Nov