Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000543.1:
Cluster 1RiPP17872

BGC0000543, pep5 biosynthetic gene cluster from Staphylococcus epidermidis. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: pep5
PubChem ID: 16132355
SMILES string: Copy to clipboard
Molecular formula: C153H258N46O41S6
Average molecular mass: 3590.388 Da

Class-specific details

Biosynthetic class(es):
RiPP subclass:

Gene cluster description

pep5 (BGC0000543). Gene Cluster 1. Biosynthetic class = RiPP. GenBank Z49865. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

pepA leader / core peptide, putative Class I


Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Homologous known gene clusters

Literature references

1. Meyer C et al. (1995) Nucleotide sequence of the lantibiotic Pep5 biosynthetic gene cluster and functional analysis of PepP and PepC. Evidence for a role of PepC in thioether formation. Eur J Biochem 232(2):478-89.