LOCUS       BGC0000545             12802 bp    DNA     linear   BCT 15-APR-2005
DEFINITION  Ruminococcus gnavus ruminococcin A gene cluster.
ACCESSION   BGC0000545
VERSION     BGC0000545
KEYWORDS    .
SOURCE      [Ruminococcus] gnavus E1
  ORGANISM  [Ruminococcus] gnavus E1
            Bacteria; Firmicutes; Clostridia; Eubacteriales; Lachnospiraceae;
            Mediterraneibacter.
COMMENT     On Sep 3, 2001 this sequence version replaced AJ276653.1.
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 19:49:26
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12802
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             <1..297
                     /codon_start=1
                     /db_xref="InterPro:IPR009835"
                     /db_xref="UniProtKB/TrEMBL:Q93JQ0"
                     /note="ORF1"
                     /product="hypothetical protein"
                     /protein_id="CAC60272.1"
                     /transl_table=11
                     /translation="DRKNIIYGHNMKDGSMFHVLRNYQDIDFFQENTGMEVYLPDKRIL
                     KYQITACEQVPADSEIYQVEKGNTEEKEGNEIILSTCSAKANIRIVIKAELEA"
     source          1..12802
                     /country="France"
                     /db_xref="taxon:935582"
                     /mol_type="genomic DNA"
                     /organism="[Ruminococcus] gnavus E1"
                     /strain="E1"
     protocluster    1..12802
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6550:9295]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6551..9295
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..12802
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..12802
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000545"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..12802
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /subregion_numbers="1"
                     /tool="antismash"
     stem_loop       complement(338..362)
                     /note="putative rho-independent transcriptional terminator"
     CDS             complement(561..911)
                     /codon_start=1
                     /db_xref="GOA:Q93JP9"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR011006"
                     /db_xref="UniProtKB/TrEMBL:Q93JP9"
                     /function="putative response-regulator"
                     /gene="rumR2"
                     /product="RumR2 protein"
                     /protein_id="CAC60273.1"
                     /transl_table=11
                     /translation="MKKILLIDDNINFLKPLSNLLQKNFDVYMATGVKEAIQILESIHI
                     DMICSDYFMGDGTGLDIIKKVNSLNICIPFIILSGLEDPELIQEVESCHAIFLNKTNPE
                     LLSKLCTIGYSE"
     gene            complement(561..924)
                     /gene="rumR2"
     regulatory      complement(919..924)
                     /gene="rumR2"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(958..1254)
                     /gene="rumH"
     CDS             complement(958..1254)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q93JP8"
                     /function="putative ABC-transporter integral membrane
                     protein"
                     /gene="rumH"
                     /note="immunity to ruminococcin A"
                     /product="RumH protein"
                     /protein_id="CAC60274.1"
                     /transl_table=11
                     /translation="MKKKKVKILSICAFVFSLLPLATLIPTFLGITLTNGIQTAWAGAN
                     ILFILVGLVLSIICVRHAENRRVLNILSTIISIFWLLLMTGIIAFAVLLTFKS"
     CDS             complement(1261..2025)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q93JP7"
                     /function="putative ABC-transporter integral membrane
                     protein"
                     /gene="rumG"
                     /note="immunity to ruminococcin A"
                     /product="RumG protein"
                     /protein_id="CAC60275.1"
                     /transl_table=11
                     /translation="MNFSELLKIEFMKVKRSKIIPLIFIAPILVIISGIANLSTYFTPE
                     YTNAWPAMFIQSALVYAYYLLPFSMIVVCVMIAGRETQNNGILKMLALPVSRYSLSLAK
                     FCVLVFYLFMEMAVFMVVFIIAGLIATATMGITETLPILYLLKWCIGLFLTMLPCVATM
                     WAITVLFEKPLLSVGLNLLLIIPGILVANTPLWIVYPYCYSGYLVSCSLHDFTAVSSDS
                     TFELMPFLPCAIIVFVLVLAVSIKAFGKKEMR"
     gene            complement(join(1261..2025,2035..2040))
                     /gene="rumG"
     regulatory      complement(1264..1267)
                     /gene="rumH"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(1264..1267)
                     /gene="rumH"
     regulatory      complement(2035..2040)
                     /gene="rumG"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(2096..2764)
                     /gene="rumE"
     CDS             complement(2096..2764)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q93JP6"
                     /function="putative ABC-transporter integral membrane
                     protein"
                     /gene="rumE"
                     /note="immunity to ruminococcin A"
                     /product="RumE protein"
                     /protein_id="CAC60276.1"
                     /transl_table=11
                     /translation="MKTLMIELRKEKRTGVLPILLAMGVLGAAYAFLNFIIRKDTLLSL
                     PLAPMDILLTQLYGMLMVLNMFGIIVATCMIYNMEFKGEAIKKMYMLPINVSSMYLCKF
                     VILTVLLLIAVLIQNLALLKIGITDLPVGTFNLNMLIVFTGYSFITSMPVLSFMLLISS
                     HFENMWISLGIGVGGFLSGMAIANSKFILFMVHPFVLMLKPAVALNASPNPTVIIFSLI
                     "
     CDS             complement(2761..3525)
                     /codon_start=1
                     /db_xref="GOA:Q9L3F4"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="UniProtKB/TrEMBL:Q9L3F4"
                     /function="putative ABC-transporter (ATP-binding domain)"
                     /gene="rumF"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 169.1; E-value:
                     2.1e-51)"
                     /gene_kind="transport"
                     /note="immunity to ruminococcin A"
                     /product="RumF protein"
                     /protein_id="CAB93668.2"
                     /transl_table=11
                     /translation="MEYIITTEKLTKKYKNFTSVNKVSLHIKKGSIYGFLGPNGAGKST
                     TMKMLLGLTAPTSGSFQIDGKQFPNDRLTILKRIGSFIEAPSFYANLTGRENLDIIRRI
                     LGLPQNAVEDALDLVGLSQFGDRLAKKYSLGMKQRLGLAGALLGRPPILILDEPTNGLD
                     PSGIHEIRNLIKSLPTFYDCTVLISSHMLSEIELIADDIGILNHGRMLFEGSLDDLKQT
                     ALQSGFATDNLEDMFLSMIENDNISRKKRAQL"
     gene            complement(join(2761..3525,3535..3541))
                     /gene="rumF"
     regulatory      complement(2773..2778)
                     /gene="rumE"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(2773..2778)
                     /gene="rumE"
     regulatory      complement(3535..3541)
                     /gene="rumF"
                     /regulatory_class="ribosome_binding_site"
     regulatory      3660..3665
                     /gene="rumR"
                     /regulatory_class="ribosome_binding_site"
     gene            join(3660..3665,3674..4375)
                     /gene="rumR"
     CDS             3674..4375
                     /codon_start=1
                     /db_xref="GOA:Q9L3F3"
                     /db_xref="HSSP:P13792"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR001867"
                     /db_xref="InterPro:IPR011006"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="UniProtKB/TrEMBL:Q9L3F3"
                     /function="putative response-regulator"
                     /gene="rumR"
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 182.6; E-value: 1.3e-55)"
                     /gene_kind="regulatory"
                     /product="RumR protein"
                     /protein_id="CAB93669.1"
                     /transl_table=11
                     /translation="MDNSYLKSKKLLLVDDEPELLTMLTTILFDDGFNYIVMASTVQEA
                     ISKARSEKPDLIFLDVMLPDGDGFSLMQQLRKFTDVPVIFLTAKDEATAKLSGLGLGAD
                     DYIVKPFMPQELLFRTYAVLRRCYKGEALTVSLDGCIIDFGRAEINKNGEIPSLTAKEH
                     ILLETLARNEGKIVTVDVLCEALWGDNPFGFENSLNAHIRRIREKIEEDPSKPVSLITI
                     KGLGYKLNTRK"
     regulatory      4367..4372
                     /gene="rumK"
                     /regulatory_class="ribosome_binding_site"
     gene            4367..4372
                     /gene="rumK"
     gene            4380..5759
                     /gene="rumK"
     CDS             4380..5759
                     /codon_start=1
                     /db_xref="GOA:Q9L3F2"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR005467"
                     /db_xref="InterPro:IPR009082"
                     /db_xref="UniProtKB/TrEMBL:Q9L3F2"
                     /function="putative histidine-kinase"
                     /gene="rumK"
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 141.6; E-value: 7.6e-43)"
                     /gene_kind="regulatory"
                     /product="RumK protein"
                     /protein_id="CAB93670.1"
                     /transl_table=11
                     /translation="MKSFRTYISKQLSVFLGLIFALIFLNTIMFGWTFYNIMHKDYGSE
                     SPQTMLEETVSSFDGTDISSKVAEKLTHNNIWAFFLNEDGVVTWSHNKPKKVPNTYKIK
                     DVAVFAKGYIQDYPVFTWECEGGIMVLGYPEDSYTKITSNYFSLDAIRKLPIFILIMFC
                     LDIFLLFIAYFLSKRKIIKTTEPIIAAIKNLSDGKSVSISVDGELVEIAEGVNRAAIIL
                     DRQNQARANWISGVSHDIRTPLSMIMGYAQRISDETEGESLIHNEAVIIRKQSMKIKEL
                     VQDLNLVSQLEYSMQPLNKTKIRFSALLRSYVAELLNEGIPEKYSINLEVSSFVEQFWI
                     DCDERLITRAISNLVQNSIRHNPKGCEIVIRLDYVEHGFELQIKDNGIGLSEKRLRELQ
                     EIPHYMESTDERLDLRHGLGLIIVRQIVIAHGGKIKIDSEPNRGYTTTIFLPINDLSKN
                     R"
     stem_loop       5757..5801
                     /note="putative rho-independent transcriptional terminator"
     regulatory      5913..5918
                     /gene="rumA1"
                     /regulatory_class="ribosome_binding_site"
     gene            5913..6069
                     /gene="rumA1"
     CDS             5926..6069
                     /codon_start=1
                     /db_xref="GOA:P83674"
                     /db_xref="InterPro:IPR007682"
                     /db_xref="UniProtKB/Swiss-Prot:P83674"
                     /function="ruminococcin A pre-lantibiotic"
                     /gene="rumA1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) leader_d"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /product="pre-RumA"
                     /protein_id="CAB93671.1"
                     /sec_met_domain="L_biotic_A (E-value: 1.4e-27, bitscore:
                     85.3, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="leader_d (E-value: 2.4e-07, bitscore:
                     20.8, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNDVLTLTNPMEEKELEQILGGGNGVLKTISHECNMNTWQFLFT
                     CC"
     CDS_motif       5926..5994
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRNDVLTLTNPMEEKELEQILGG"
                     /locus_tag="rumA1_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       5995..6069
                     /prepeptide="core"
                     /locus_tag="rumA1_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="4.80"
                     /molecular_weight="2675.1"
                     /monoisotopic_mass="2673.2"
                     /core_sequence="GNGVLKTISHECNMNTWQFLFTCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRNDVLTLTNPMEEKELEQILGG"
                     /leader_location="[5925:5994](+)"
                     /alternative_weights="2693.1"
     regulatory      6072..6077
                     /gene="rumA2"
                     /regulatory_class="ribosome_binding_site"
     gene            6072..6230
                     /gene="rumA2"
     CDS             6087..6230
                     /codon_start=1
                     /db_xref="GOA:P83674"
                     /db_xref="InterPro:IPR007682"
                     /db_xref="UniProtKB/Swiss-Prot:P83674"
                     /function="ruminococcin A pre-lantibiotic"
                     /gene="rumA2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) leader_d"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /product="pre-RumA"
                     /protein_id="CAB93672.1"
                     /sec_met_domain="L_biotic_A (E-value: 1.4e-27, bitscore:
                     85.3, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="leader_d (E-value: 2.4e-07, bitscore:
                     20.8, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNDVLTLTNPMEEKELEQILGGGNGVLKTISHECNMNTWQFLFT
                     CC"
     CDS_motif       6087..6155
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRNDVLTLTNPMEEKELEQILGG"
                     /locus_tag="rumA2_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       6156..6230
                     /prepeptide="core"
                     /locus_tag="rumA2_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="4.80"
                     /molecular_weight="2675.1"
                     /monoisotopic_mass="2673.2"
                     /core_sequence="GNGVLKTISHECNMNTWQFLFTCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRNDVLTLTNPMEEKELEQILGG"
                     /leader_location="[6086:6155](+)"
                     /alternative_weights="2693.1"
     regulatory      6234..6239
                     /gene="rumA3"
                     /regulatory_class="ribosome_binding_site"
     gene            6234..6392
                     /gene="rumA3"
     CDS             6249..6392
                     /codon_start=1
                     /db_xref="GOA:P83674"
                     /db_xref="InterPro:IPR007682"
                     /db_xref="UniProtKB/Swiss-Prot:P83674"
                     /function="ruminococcin A pre-lantibiotic"
                     /gene="rumA3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) leader_d"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /product="pre-RumA"
                     /protein_id="CAB93673.1"
                     /sec_met_domain="L_biotic_A (E-value: 1.4e-27, bitscore:
                     85.3, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="leader_d (E-value: 2.4e-07, bitscore:
                     20.8, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNDVLTLTNPMEEKELEQILGGGNGVLKTISHECNMNTWQFLFT
                     CC"
     CDS_motif       6249..6317
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRNDVLTLTNPMEEKELEQILGG"
                     /locus_tag="rumA3_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       6318..6392
                     /prepeptide="core"
                     /locus_tag="rumA3_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="4.80"
                     /molecular_weight="2675.1"
                     /monoisotopic_mass="2673.2"
                     /core_sequence="GNGVLKTISHECNMNTWQFLFTCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRNDVLTLTNPMEEKELEQILGG"
                     /leader_location="[6248:6317](+)"
                     /alternative_weights="2693.1"
     stem_loop       6430..6465
                     /note="putative rho-independent transcriptional terminator"
     regulatory      6540..6545
                     /gene="rumM"
                     /regulatory_class="ribosome_binding_site"
     gene            join(6540..6545,6551..9295)
                     /gene="rumM"
     CDS             6551..9295
                     /codon_start=1
                     /db_xref="InterPro:IPR007822"
                     /db_xref="UniProtKB/TrEMBL:Q9L3F1"
                     /function="putative ruminococcin A modifying enzyme"
                     /gene="rumM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     635; E-value: 3.7e-192)"
                     /gene_kind="biosynthetic"
                     /product="RumM protein"
                     /protein_id="CAB93674.2"
                     /sec_met_domain="LANC_like (E-value: 3.8e-73, bitscore:
                     236.1, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="DUF4135 (E-value: 4.2e-76, bitscore:
                     246.4, seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHKKFCGLYIEYIFEYIIETLKEKEDYLFDSEKIKYVKEIIEKEI
                     FQRVFKSLLYCMNVERLDGNLSGNTPEERYEMFSNTRYCIEAMGKNFPTMRNQIYDEMA
                     HKCVYVMEVIRELENNKNKIGRHFGINPGEIVQVQNSGDWHDSECVLIFTFQSQDKIVY
                     KPTRGENLQFMKGFMDYFFEPEYAEQYIGLCIRKGTWVKFVKHIELTNSRNVERFYYNY
                     GKVLFVAYILGMNDIHYENLIACGEYPVITDVETIFSSYLFFDTHTFLYDAQYKAVKEL
                     LYGTMATGMLPIFSMTDYFGGDVSCLSNKGIQLIVEKIKNEYRDDMYICTAPEMIVEYK
                     HLPNHTIDPLMYGKQIVQGFEEAENNFGEKKVEIINYILNNMGKVESRIILNMTKGYSK
                     IVRIKSDPRYRHEPELFGHLLTTLKRTNQFNPEVYEQEVTELCRSNIPSFYWKMDMNCV
                     YGLNLGQKKKILDLPIFTKERLSEILEYQINIQMLEKQKQLIYDAIVSNIALGIEYEKL
                     KISVKQHVDIHVKKVLRRNIDQNCIVGSDGTISWLGLMVNDKEQLEYAMLDWSLYSGII
                     GLGYMYISEYDKEPDVLAKDMLQRIFCTLAKSYDLGVFKEYDISYFCGLTGIYAFLKQI
                     KDRNIIEPDIIEKYIKNIQEAIRNNIVKTSSYDTLAGIHSAVIYYFGCYEQDIFSREIL
                     SSIEEYFLNSFKIDDMKRNFNYASFAHGYSGVMTSIMCMLQHKYDIKLEKILCELWKEE
                     KELYVEKFIWKDMRAHHIVHSHYWCHGSVGIMMARLIWKKFGFDKKFAEDIEEENLEEI
                     LSKYKEELLNKKFQSKNYSLCHGNFALIDFLISYRKIVGTDERIDAYIEEIIESGQENG
                     YSCVGAPGAINSIGFMVGEAGIQYTENRSENSKLHSVLMLETV"
     regulatory      9294..9300
                     /gene="rumT"
                     /regulatory_class="ribosome_binding_site"
     gene            join(9294..9300,9314..11380)
                     /gene="rumT"
     CDS             9314..11380
                     /codon_start=1
                     /db_xref="GOA:Q93JP5"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR005074"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="UniProtKB/TrEMBL:Q93JP5"
                     /function="putative ABC-transporter"
                     /gene="rumT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 152.6; E-value:
                     2.7e-46)"
                     /gene_kind="transport"
                     /product="RumT protein"
                     /protein_id="CAC60277.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 6.4e-35, bitscore:
                     109.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVILQTNQSDCLLACAAMIMNTLGCKVPVYKLIEKIELSMAGSN
                     ILQLKEALGEYGFSVEGYKIDVQSLNQTIMPVIAYVKNGHFIVLDKMSKNQFTGVDPAI
                     GRIKYSYDEFQKIYSGVIVKIRRVDAGRKSEEVTRKSLLSFLADKRLFRILAGLLVTSI
                     FTQVVAMSYSYMYSMVGNGETYGKVMLLLCGAVILLGIGSIMQGVLTKKFNILYEQIYG
                     NRLVDKLMSKNYKFFSFRSNGDLLYRINARGMIKDALLLKLVPSFISLCTIIFVQILLL
                     VQNSLLGILFLGAIILYLVVYVGTSKIAYMESNKYTQKVIQLNTTSENIIRSVSTIKVL
                     GVSSIFTKKWHEENQQQAECYGELVVIQSFQNILTNIFTYIVPIAVSILSIACDEEINI
                     FSQMALLPLLYLVVQNVVVIGQACNSIYTVLPNIDKATELLDDEFMQDNERKFAKLDGN
                     TAIQVNDMSYHYGSLQCLEKVNIRIEKGKKYAVVGVSGSGKSTMLKILANLLNDYHGEV
                     VFDEQCREKPIYLDQDTTILDGSILENVLFGQTCTNERLIQISEAIGLNEVVGRQPQNW
                     GTEIAKGKNLSRGQEQRICLARCLIKEADTYLLDEATSNIDVVDEDKIMKALIGNQGIL
                     EEKTVLISTHKLSMIDYVDEVIYIKNGRVYQGTHMQLLQKEKSYAAFFEGKVT"
     regulatory      11887..11892
                     /note="ORF14"
                     /regulatory_class="ribosome_binding_site"
     CDS             11898..12578
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q93JP4"
                     /note="ORF14"
                     /product="hypothetical protein"
                     /protein_id="CAC60278.1"
                     /transl_table=11
                     /translation="MKCKFFKVAALCCTCMMVLGNTMAVYAEEQPMVISEPNVTSSEME
                     KLIEVVLDIKEANPGKSEQEIFEIVSKSLENERKETRGISDILECFDGKQKKKLLIRYP
                     LDALKVNDAKNIATRQTERKFGHNGLGDRSDAFRHGIWNAEMTILIGAEKAELFATAHE
                     EKDTTGVEPDGHTKVEHKNMDLHNNNVGREIGLAHPDLSEEQMADYIYDVIYQENTPFV
                     WLND"
     stem_loop       12579..12627
                     /note="putative rho-independent transcriptional terminator"
ORIGIN
        1 gatcgtaaga atattattta tgggcataac atgaaagatg gcagtatgtt ccatgtgctg
       61 agaaattatc aggacattga tttttttcag gagaacacgg gtatggaggt ttatttaccg
      121 gataaaagga ttctgaaata tcagattacg gcttgtgagc aggtgccagc ggatagtgaa
      181 atttatcagg tagaaaaagg aaacactgag gagaaagagg gaaatgaaat tatattgtct
      241 acttgtagtg caaaagcaaa tatccggatt gttataaaag cagagctaga ggcgtaaaat
      301 tatcgaaata taatttattt accattatag gcaaaaagga agtagagtaa atctctactt
      361 ccgaatcata catctttttc ctatgatata ggtacgagat aaactgataa aagaactagt
      421 atgctgaaat acacaaataa accaactttt gcaattgttt gaagattttg ataggatttt
      481 actgttcata aagccctctt tttatattca gaaattatta tcgttgactc atctcctacg
      541 tggaagcgtt taaaattatt ttattcagaa tatccaatag tacagagttt tgatagcaat
      601 tcaggatttg ttttattcaa aaatattgca tggcatgatt ctacttcctg aataagttct
      661 ggatcttcga gaccggatag aataatgaaa ggaatgcaga tatttagaga atttactttt
      721 tttatgatat ccaatcccgt tccatcgccc ataaaatagt cagaacaaat catatctata
      781 tgaattgatt caagaatttg tattgcttct tttacgccag ttgccatata tacatcaaaa
      841 tttttctgaa gcaaattgga caacggtttt aaaaagttga tattatcgtc tataagaagt
      901 atttttttca aaaatacacc tcctagtgta ataataattt cagaggaaca tgttgcctta
      961 tgatttaaac gtaagtagta ctgcgaaagc gataattccg gtcattaaca ataaccagaa
     1021 aatgctgatt attgttgaaa gaatgtttaa tactctcctg ttttctgcat gacgcacaca
     1081 aataatagaa agtactaaac cgactagaat aaataagata tttgcacctg cccatgcagt
     1141 ttgtattcca tttgtgagtg ttataccaag gaatgtagga ataagtgttg caagagggag
     1201 caggctaaaa acaaatgcgc atatactaag aattttgact ttcttttttt tcatacttaa
     1261 ttacctcatt tcttttttcc caaaagcttt aatagataca gccaaaacaa gtacaaatac
     1321 aattattgca catggcaaga atggcatgag ttcaaatgta gagtcagaag aaaccgctgt
     1381 aaagtcatgt aatgaacaag atacaagata tccactgtaa cagtaaggat aaacaatcca
     1441 cagtggggta tttgcaacta agataccagg aattataagt aatagattta aaccaacgga
     1501 aagcagtggt ttttcaaata aaaccgtaat tgcccacata gttgctacac atggaagcat
     1561 agtaaggaaa agtccaatac accattttag taagtatagt attggtagtg tttcagtaat
     1621 tcccatagtg gctgttgcaa taagacctgc gataataaaa acgaccataa aaacagccat
     1681 ttccataaag aggtaaaaaa caagaacaca aaatttggcc aaagaaagtg agtatctgct
     1741 gacaggtaaa gccagcattt ttaaaatacc gttgttttgt gtttctcgtc cagcaatcat
     1801 tacacaaacc acaatcatac taaaaggaag tagataatag gcataaacaa gagcgctttg
     1861 gataaacata gcaggccagg catttgtata ttccggagtg aaataagtac ttaggtttgc
     1921 aattccagaa ataattacca agataggagc gataaaaata agtggaataa ttttagagcg
     1981 ctttactttc ataaattcta tttttagtaa ttcagagaaa ttcatttgtt tgatcctcct
     2041 attcataatg ataatttttg gtgagccata gtccaactcc gagaaaagcg aaagtttata
     2101 ttaaagagaa gattatgaca gtaggattag gtgaggcatt cagtgcaaca gccggtttta
     2161 acattaatac aaatggatga accataaata atatgaattt ggaattggct attgccattc
     2221 cacttaggaa gccaccaacg cctatcccga gagaaatcca catattttca aagtgagaag
     2281 aaattaataa catgaatgaa agtactggca tggatgtaat aaaggaatat ccagtaaata
     2341 caattagcat attcaaatta aatgttccta caggtaaatc agtaatacct atttttagta
     2401 gtgcaaggtt ttgtattaag acagcaatta gaagtaacac tgtcaagata acaaacttgc
     2461 aaagatacat ggaagaaaca tttataggta gcatatacat tttcttgatt gcttcaccct
     2521 taaattccat attataaatc atacatgttg caacaataat tccaaacata tttaaaacca
     2581 tgagcattcc atagagttgt gttaataata tgtccattgg agctagcggc aaacttaata
     2641 aggtatcctt tctaattatg aaattaagaa aagcgtaagc agctccaaga acccccatgg
     2701 ctaaaagaat tggtagtaca ccagtccttt tttctttacg cagttcaatc ataagtgttt
     2761 tcataactga gccctcttct ttctagatat attgtcgttt tcaatcatgg aaagaaacat
     2821 atcttccaga ttgtcagtag caaatccaga ttgcaaagca gtttgtttta agtcatctaa
     2881 actaccttca aaaagcattc ttccatgatt aagaatccca atatcgtcag caatcaattc
     2941 aatttcagaa agcatatggg aagagattaa aacagtacaa tcataaaagg taggaagaga
     3001 ttttattaaa ttgcgaattt cgtggatgcc ggaagggtct aaaccgttgg tcggctcatc
     3061 caaaattaaa attggtggtc tcccgagtaa tgcaccagct aatcccaaac gttgtttcat
     3121 gcctaatgag tatttttttg ccagtcgatc accaaactga cttaagccaa ctaaatctaa
     3181 agcatcttca actgcatttt ggggtaatcc cagtattctg cgaattatat cgagattttc
     3241 gcgaccagtt aggttagcgt aaaaggatgg agcttcaatg aaggagccaa ttcttttcaa
     3301 aatagtaagc cggtcatttg gaaattgttt tccatcaatt tggaaacttc cgcttgttgg
     3361 agctgttagt cctaaaagca ttttcatagt ggtggatttt cctgcaccat tgggcccaag
     3421 gaaaccataa atacttccct ttttgatatg aagtgaaact ttgttgactg aagtgaaatt
     3481 tttatatttt tttgtcaact tttctgttgt tataatgtat tccatataaa catctccttt
     3541 cgttaatcat atgttacact atgaacctga catttacatt ctcgtatcct tacttttacc
     3601 ttactttttg taaaaagtga tcaagaaata tgaaactgtg ttataatagg cacatagata
     3661 ggaggtaggt aagatggaca attcatattt aaaaagcaaa aaactgttgt tggtagatga
     3721 tgaacccgaa ctattgacaa tgttaacgac tattttgttt gatgatggat ttaattatat
     3781 tgtgatggca agtactgtac aagaagcaat ttcaaaagca cgtagcgaaa aaccggattt
     3841 gatttttctt gatgttatgt tacctgatgg agacggattc agtttaatgc aacaattacg
     3901 gaaatttaca gacgtaccag tgattttttt gactgcaaaa gatgaggcta ctgctaaatt
     3961 atctggtttg ggattaggag cagatgacta tatagtgaaa ccgtttatgc cacaggaact
     4021 gttgttccgc acatatgcag ttttaaggcg atgctacaaa ggagaggcat taacagtttc
     4081 attggatggg tgtattatag attttggacg tgcagaaata aataaaaatg gtgaaattcc
     4141 ctctttaaca gctaaggaac atattttatt ggaaacactt gctagaaatg aaggaaagat
     4201 tgttactgta gacgttttgt gtgaagcact gtggggagat aatccatttg gctttgagaa
     4261 tagtttaaat gcacacattc gaagaattcg agaaaaaatc gaagaggatc cgtcaaaacc
     4321 tgtatcgttg attacaataa aaggacttgg atacaaatta aatacaagga agtaacataa
     4381 tgaaatcgtt taggacatat atatcaaaac agttgtctgt ttttttggga ttgatttttg
     4441 ccttgatatt tttaaatact ataatgtttg gatggacatt ttataatatc atgcataaag
     4501 attatggttc agaatcaccg cagactatgc tagaagaaac agtttcttct tttgatggaa
     4561 cagatatttc aagcaaagtt gcagaaaaat taacccataa caatatttgg gccttttttc
     4621 tgaatgagga tggagtagta acatggtcgc acaataaacc gaaaaaggtt ccgaatactt
     4681 ataagataaa agatgttgca gtatttgcaa aaggatatat ccaggactat ccagttttta
     4741 cttgggaatg tgagggcggg attatggttt tagggtatcc agaagatagt tatacaaaga
     4801 ttacaagcaa ttatttttct cttgatgcga taagaaaact acctattttc attttaatta
     4861 tgttttgttt ggatatattt cttttattta tagcatattt cttatcaaag agaaaaatca
     4921 taaaaactac agaaccaata atcgctgcaa ttaaaaacct ttcagatgga aagtcggttt
     4981 cgatttctgt tgatggcgaa ctggtagaaa ttgcagaagg ggtaaatcga gcggcgatta
     5041 ttttagatag gcaaaatcaa gccagagcaa attggataag tggagtttct catgatatac
     5101 gaacccctct ttcgatgata atgggatatg cacaacggat ttcagatgaa acagagggag
     5161 aaagtttaat tcataacgaa gcagtgatta ttcgcaaaca gagtatgaaa ataaaagaat
     5221 tagtacaaga tctgaatttg gtatcacagt tagaatattc tatgcaaccg ttaaacaaaa
     5281 caaaaattcg tttttcggct ttgttacgta gttatgtggc tgaattattg aatgaaggta
     5341 ttcctgaaaa atattctatt aatcttgaag tttcttcatt cgtagagcag ttttggatag
     5401 attgtgacga acggcttata acacgagcaa taagcaactt ggtacaaaat agtattcgac
     5461 acaacccaaa gggctgtgaa attgtaatta gattagatta tgtagaacat ggatttgaat
     5521 tacaaataaa agataacggg attggattat ccgaaaaaag gttacgggaa ttacaagaaa
     5581 ttcctcacta tatggagagt acagacgagc gtttggactt acgccatgga ttggggctga
     5641 ttattgtaag acaaatagta atagcacatg gaggaaagat aaaaattgat agtgaaccta
     5701 ataggggata tactactact atttttcttc caattaatga tttatcaaaa aatcgataag
     5761 ttaaaaggca gtttcagtgg gaactgcctt ttaacttgga aaaatttaga aagatggtaa
     5821 atattacatg gaagaagggt gaaatttacg agacagaaat atcaaaagaa attcatgata
     5881 gtatatgacc ataatcttat ttgagaaaag aaaggagaaa aaaatatgag aaatgatgta
     5941 ttaacattaa caaacccaat ggaagaaaaa gaactggagc agatcttggg tggtggtaat
     6001 ggtgtgttaa aaacaatcag ccacgaatgc aatatgaata catggcagtt cctgtttaca
     6061 tgctgctaaa aaggaggata aacgatatga gaaatgatgt attaacatta acaaatccaa
     6121 tggaagaaaa agaactggag cagattttgg gtggcggcaa tggtgtgtta aaaacaatca
     6181 gccacgaatg caatatgaac acatggcagt tcctgtttac atgctgctaa aaaaggagga
     6241 taaatgatat gagaaatgac gtattaacat taacaaaccc aatggaagaa aaagaactgg
     6301 agcagatttt gggtggcggt aatggtgtgt taaaaacaat cagccacgaa tgcaatatga
     6361 atacatggca gttcttgttt acatgctgtt aattgcaatt tgaatattac ttctcaaata
     6421 agatttactg tacaggctgc ttagattatt ctgagtagcc tgttcttata aaagaagatt
     6481 tcctcaaaat acattatggt gtattgaata atatatgagg aattcaaaat aaatattaca
     6541 ggaggtaagt atgcataaga agttttgtgg tctttatatt gaatatattt ttgaatacat
     6601 catagagaca ttaaaagaga aagaggatta tctttttgat agtgaaaaaa ttaaatatgt
     6661 aaaagaaatt attgaaaagg agatttttca aagagttttt aaatcgctac tatattgtat
     6721 gaatgtagag cgattagatg gaaatttatc tggaaatact ccagaggaac gttatgaaat
     6781 gttcagtaat acgagatact gtatagaggc aatgggcaag aattttccaa caatgagaaa
     6841 tcaaatatat gacgagatgg cacataaatg tgtatatgta atggaagtaa ttagagaact
     6901 tgaaaataac aagaataaaa ttggtagaca ttttgggatt aacccgggag aaattgtaca
     6961 agtgcaaaat agtggagatt ggcacgatag tgaatgtgtc ttaattttta cattccaatc
     7021 tcaagataaa attgtataca aaccaacccg aggagaaaat ttgcaattta tgaaagggtt
     7081 tatggactat ttttttgaac cagaatatgc cgaacaatac ataggtttgt gtatcaggaa
     7141 aggtacttgg gtaaagtttg tcaagcatat cgaactaaca aattcaagaa atgttgaacg
     7201 gttttattat aattacggaa aagtgttatt tgtcgcatat attttaggaa tgaatgacat
     7261 tcattatgaa aatcttattg catgtgggga atacccagta attacggacg ttgaaacaat
     7321 tttttcctcg tacttatttt ttgatacaca tacattctta tatgacgcac agtataaagc
     7381 tgtaaaagaa ttgctctacg gtacaatggc aacagggatg ctaccgattt tttccatgac
     7441 ggattatttt ggtggagatg tgagttgttt atcaaataaa ggaatacagt tgattgtaga
     7501 aaaaattaaa aatgagtata gagatgatat gtatatttgc actgcaccag agatgatagt
     7561 agaatataaa catttgccaa atcatacaat tgatcctttg atgtatggaa aacagattgt
     7621 gcaagggttt gaggaagcag aaaataattt tggggagaaa aaggtagaaa tcataaatta
     7681 cattttgaat aatatgggaa aagttgagtc acgaattatt ttgaatatga caaaaggcta
     7741 ttcaaaaatt gttcgaatta aaagtgatcc aaggtatcgg catgaaccag aattatttgg
     7801 acatttgttg acaacattaa aaagaaccaa tcaatttaat cctgaagtat atgaacagga
     7861 agttacggaa ctctgccgta gtaatatacc tagtttttat tggaagatgg acatgaattg
     7921 tgtatatggt ttgaatttag gacagaaaaa aaagatattg gatcttccta tttttacaaa
     7981 agagagatta tcagaaattc ttgaatatca gattaatata caaatgttag aaaaacagaa
     8041 acagttaata tatgatgcta ttgtctctaa tatagcatta ggtattgaat atgaaaagtt
     8101 gaaaataagt gtgaagcaac atgtggatat tcatgtaaaa aaagtacttc ggagaaatat
     8161 tgatcagaat tgcattgtag gttcagatgg aactattagt tggcttggac ttatggtaaa
     8221 tgataaagaa cagttagaat atgctatgtt ggattggtct ttatactctg gaattatagg
     8281 acttggctat atgtatattt ccgaatatga taaagagcca gatgtattgg caaaagatat
     8341 gctacaaaga atattttgta cgctggcaaa atcatatgat ttaggtgttt ttaaagaata
     8401 tgatatttct tatttttgcg gattgacagg catttatgcg ttcttgaaac aaattaaaga
     8461 ccgaaatata attgagccgg atatcataga aaaatatata aaaaatattc aagaagcaat
     8521 aagaaataat attgttaaaa ctagcagtta tgatactttg gcaggaattc attcagcagt
     8581 tatttattat tttgggtgtt atgaacaaga catattttcc agagagattt tatcatctat
     8641 agaagagtat tttttaaata gttttaaaat tgatgatatg aagagaaact ttaattatgc
     8701 aagttttgca catgggtatt caggagttat gacatcaatt atgtgtatgc ttcagcataa
     8761 atatgatata aaattagaaa aaattttatg tgagctgtgg aaagaagaaa aagaattgta
     8821 tgttgaaaaa tttatatgga aagatatgcg agctcatcat atcgtacatt cacattactg
     8881 gtgtcatggt tcagtaggta ttatgatggc aagattgatt tggaaaaaat ttgggtttga
     8941 taaaaaattt gctgaagata tagaagagga aaatttagaa gaaatattgt ctaaatataa
     9001 agaagaactt cttaataaaa aatttcaatc taaaaattat tctttatgcc atgggaattt
     9061 tgctttaatc gattttctta tttcttatag aaaaattgta ggaactgatg aaagaataga
     9121 tgcatatata gaggaaatta ttgagagtgg tcaagaaaat ggatacagtt gtgttggagc
     9181 accgggagct ataaactcaa taggatttat ggttggagaa gcaggtattc aatatacaga
     9241 aaatagaagt gagaattcaa agttgcactc tgttttaatg cttgaaactg tgtaagaaag
     9301 tgtggtgata ttagtgaaag ttattttaca aacaaatcaa tctgactgtt tactagcatg
     9361 tgctgctatg attatgaata cgcttgggtg caaggtgcca gtatataaat tgattgagaa
     9421 gatagaatta tctatggctg gaagtaatat attgcagtta aaagaggcat taggagaata
     9481 tggtttttct gtggaaggat ataagattga tgtacagagt ctcaaccaga caataatgcc
     9541 agtcattgct tatgtaaaga atggtcattt tattgttctt gacaaaatga gtaaaaatca
     9601 gtttactggg gtagatccag caattggacg aattaagtat tcttatgatg aatttcagaa
     9661 aatatatagt ggtgtaattg tgaaaatcag aagagtagat gcgggcagaa aatctgagga
     9721 ggtaactaga aaaagtctgt taagtttctt agcagataaa agactgtttc ggattttggc
     9781 tggtttactt gtaacctcaa tttttacaca ggttgtggca atgagctatt cttatatgta
     9841 ttctatggtt ggaaatggtg aaacatatgg gaaagttatg ctattactat gtggggcagt
     9901 tattttacta ggaataggaa gtatcatgca aggtgttttg actaaaaaat ttaatatttt
     9961 gtatgagcag atatacggaa ataggctagt tgataaactg atgagtaaaa attacaaatt
    10021 tttttctttt aggagcaacg gtgatttgct gtataggata aacgcaagag gcatgattaa
    10081 agatgctcta ttgctaaaat tggtaccttc tttcatttcg ctatgcacaa ttatttttgt
    10141 tcagatttta ttgctagtac aaaatagtct tctaggtata ttatttttag gtgcaattat
    10201 tttatattta gttgtatatg taggaacaag taaaatagca tatatggaaa gcaataaata
    10261 tacacaaaaa gttatacagt taaatacaac aagtgagaat atcatacgat cagtttcaac
    10321 cataaaagtt ttaggtgtta gctcgatttt tactaaaaaa tggcatgaag aaaatcagca
    10381 acaagcagag tgttatgggg aattagttgt tattcaaagt tttcaaaata ttttaactaa
    10441 tatatttaca tatattgttc caattgcggt gagtatacta agtattgcat gtgatgaaga
    10501 aattaacatt tttagtcaaa tggcacttct tccattgtta tacctagtag tacaaaatgt
    10561 agtagtgatt gggcaggctt gtaattctat ttacacagtt ttacctaata tagataaagc
    10621 gacagagttg ttagatgatg aatttatgca ggacaatgaa cggaaatttg caaaacttga
    10681 tggtaataca gcaattcaag ttaatgatat gtcctatcat tatggaagtt tgcaatgttt
    10741 ggagaaggtt aatataagaa ttgaaaaagg aaaaaaatat gctgtcgtag gagtttcggg
    10801 aagtggtaaa tctacaatgc ttaaaatttt agcaaatctt ttaaatgatt atcacggaga
    10861 ggttgtattt gatgaacaat gtagagagaa acctatttat ttagatcagg atacaaccat
    10921 tttggatggc agtatattag aaaatgttct ttttggacaa acatgcacaa atgagaggtt
    10981 gattcagata agtgaggcga ttggtcttaa tgaagtagta ggtagacagc cacaaaactg
    11041 gggaaccgaa attgcaaaag gaaagaattt gtccagggga caggaacaga ggatttgtct
    11101 tgcgagatgt ctaatcaaag aggcggatac atatctttta gatgaggcaa ctagtaatat
    11161 tgatgtagta gacgaagata aaattatgaa ggcattgatt ggaaatcaag gaattttaga
    11221 agaaaagact gtacttattt ctactcacaa gctgagtatg attgattatg tagatgaggt
    11281 tatttatata aaaaatggac gggtttatca aggaacacat atgcaattac tccaaaaaga
    11341 gaaatcgtat gcagcatttt ttgaaggaaa agttacttaa aatagcggaa taattacatg
    11401 ggaaaatttt ggagaataaa agatgatata ttgtaaaaaa caaattctcg ggatttcaat
    11461 gaacaagagc atacttgaca attgaatatt gtgcagaaaa agaaagttgt gttcgtgtgt
    11521 tccacagaag tagacaggaa ggtagtctta attctagttt gaagacagaa taacactcat
    11581 gcaggtggaa tctgtcatag aaagattaag gtactaaaac tgcatgatat aatcccaggc
    11641 gctcttatgc aaagaaaaat gatgtagata aaatttaaga aaataagata cgaaaagtat
    11701 tctgatagtc agtgtgttca ctggtgttaa caggtaagag aaaaattgat cctatccatt
    11761 gaataacata tcagcaatca gcgtcaacgt ggattattgc taaaaatagg tgatttttag
    11821 aatataaatt tctgtaggtc ttataaaacg aaacatgaag atttcgagaa gatataaaat
    11881 gaaagtgagg aaaaaagatg aagtgtaaat tttttaaagt agcagcgtta tgttgcacat
    11941 gtatgatggt attggggaat acgatggcag tttacgcaga agaacaacca atggtaataa
    12001 gtgaaccgaa tgttacttct tctgaaatgg agaaattgat tgaagtggta ttggatatca
    12061 aggaggctaa tccaggaaaa tcagaacagg aaatttttga aattgtttca aaatctttag
    12121 aaaatgagag aaaagaaaca agaggaattt cggatatttt ggaatgcttt gacggaaagc
    12181 agaaaaagaa attattaatc agatatccgc tagatgcctt gaaagttaat gacgccaaaa
    12241 acatagctac tagacagacg gaaagaaagt ttgggcataa tggattagga gatcggagtg
    12301 atgcatttag gcatggcatt tggaatgcag aaatgacaat tttaattggg gcagaaaaag
    12361 cagaattatt tgcgactgca catgaagaaa aagatacaac aggtgtagag ccggatggtc
    12421 acactaaggt agaacataag aatatggatc tgcataacaa taatgttggg agagaaatag
    12481 gacttgcaca tccagactta tctgaagagc agatggcaga ttatatatat gatgtaattt
    12541 atcaggaaaa tacgccattt gtatggctga atgattaatg caaacaaagg tggtgctaaa
    12601 gattaacttt agcatcacct ttttgcaggt agttaattct ataaatcttt ttatagattg
    12661 acaggtttaa aaattaaata attgtaaaag aataatattg tgtaaggtat tgtagtaata
    12721 aaaaagtacc taaatgagtt gtatatattc ttaaattaag ttgtattcgt atgttaataa
    12781 gtcgctttta tgtgtgtatg at
//
