Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000545.1:
Cluster 1RiPP112802

BGC0000545, ruminococcin A biosynthetic gene cluster from Ruminococcus gnavus. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: ruminococcin A

Class-specific details

Biosynthetic class(es):
RiPP
RiPP subclass:
Lanthipeptide

Gene cluster description

ruminococcin A (BGC0000545). Gene Cluster 1. Biosynthetic class = RiPP. GenBank AJ276653. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

rumA1 leader / core peptide, putative Class II
MRNDVLTLTNPMEEKELEQILGG - GNGVLKDhbIDhaHECNMNDhbWQFLFDhbCC
rumA2 leader / core peptide, putative Class II
MRNDVLTLTNPMEEKELEQILGG - GNGVLKDhbIDhaHECNMNDhbWQFLFDhbCC
rumA3 leader / core peptide, putative Class II
MRNDVLTLTNPMEEKELEQILGG - GNGVLKDhbIDhaHECNMNDhbWQFLFDhbCC

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Homologous known gene clusters

Literature references

1. Gomez A et al. (2002) Trypsin mediates growth phase-dependent transcriptional tegulation of genes involved in biosynthesis of ruminococcin A, a lantibiotic produced by a Ruminococcus gnavus strain from a human intestinal microbiota. J Bacteriol 184(1):18-28.