BGC0000553: SRO15-2212 biosynthetic gene cluster from Streptomyces filamentosus NRRL 15998
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Location: 5,221,350 - 5,228,789 nt. (total: 7,440 nt).
This entry is originally from NCBI GenBank NZ_DS999644.1.


core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
TTA codons
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Gene details
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General information about the BGC
MIBiG accession BGC0000553
Short description SRO15-2212 biosynthetic gene cluster from Streptomyces filamentosus NRRL 15998
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Remarks "The SRO15-2212 prepropeptide sequence is identical with AmfS from Streptomyces griseus IFO13350"
Biosynthetic class(es)
  • RiPP (Lanthipeptide)
Loci NCBI GenBank: NZ_DS999644.1
  • SRO15-2212
Species Streptomyces filamentosus NRRL 15998 [taxonomy]
Chemical products information
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SSGG_RS0133190
  • WP_205382163.1
  • lanKC
5221416 - >5223099 (+) class III lanthionine synthetase LanKC
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  • SSGG_RS09930
  • WP_032798142.1
5224027 - 5224227 (+) hypothetical protein
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  • SSGG_RS09925
  • WP_003966507.1
5224253 - 5224384 (+) SapB/AmfS family lanthipeptide
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  • SSGG_RS0133195
5224477 - >5225542 (+) ABC transporter ATP-binding protein
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  • SSGG_RS0133200
  • WP_032798144.1
5225826 - >5226171 (+) ATP-binding cassette domain-containing protein
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  • SSGG_RS34700
5226439 - 5228215 (+) ATP-binding cassette domain-containing protein
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  • SSGG_RS09915
  • WP_006127364.1
5228184 - 5228789 (-) response regulator transcription factor
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RiPP-specific information
Subclass Lanthipeptide
Cyclic? yes
Precursor genes
Core sequences:
  • 3x10 (Thioether)
  • 13x20 (Thioether)
Annotation changelog
MIBiG version Submitter Notes
  • Hidden contributor (ID: UK5BZZ5BLXFR5LGS2GITT5IB, no GDPR consent given).
  • Submitted
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
Similar known gene clusters
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