LOCUS       BGC0000554              6546 bp    DNA     linear   CON 17-MAR-2023
DEFINITION  Streptomyces filamentosus NRRL 15998 supercont3.1, whole genome
            shotgun sequence.
ACCESSION   BGC0000554
VERSION     BGC0000554
KEYWORDS    .
SOURCE      Streptomyces filamentosus NRRL 15998
  ORGANISM  Streptomyces filamentosus NRRL 15998
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            DS999644.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Genome Coverage: 11.9X (11.4X Q>20)
            Annotation was added to the scaffold in March 2010.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:50:14
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6546
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS_motif       1..120
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNLVRAWKDPEYRATLSEAPANPAGLVELADDQLDGVAGG"
                     /locus_tag="SSGG_RS13165_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       121..222
                     /prepeptide="core"
                     /locus_tag="SSGG_RS13165_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="0.40"
                     /molecular_weight="3056.6"
                     /monoisotopic_mass="3054.4"
                     /core_sequence="TTWACATVTLTVTVCSPTGTLCGSCSMGTRGCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNLVRAWKDPEYRATLSEAPANPAGLVELADDQLDGVAGG"
                     /leader_location="[0:120](+)"
                     /alternative_weights="3074.6"
                     /alternative_weights="3092.6"
                     /alternative_weights="3110.6"
                     /alternative_weights="3128.7"
                     /alternative_weights="3146.7"
                     /alternative_weights="3164.7"
     protocluster    1..6546
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[580:3895]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      581..3895
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..6546
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..6546
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000554"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..6546
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..222
                     /locus_tag="SSGG_RS13165"
                     /old_locus_tag="SSGG_04019"
     CDS             1..222
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126649.1"
                     /locus_tag="SSGG_RS13165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSGG_04019"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_006126649.1"
                     /transl_table=11
                     /translation="MNLVRAWKDPEYRATLSEAPANPAGLVELADDQLDGVAGGTTWAC
                     ATVTLTVTVCSPTGTLCGSCSMGTRGCC"
     gene            255..491
                     /locus_tag="SSGG_RS13160"
                     /old_locus_tag="SSGG_04020"
     CDS             255..491
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03898.1"
                     /locus_tag="SSGG_RS13160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSGG_04020"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_010071700.1"
                     /transl_table=11
                     /translation="MDIVRSWKDADYRLSLGSEAPAHPSGEGLTAITDEELTEINGAGS
                     GVLGTLGCCSCLPWYSGWTVCGLACNPGKPCKN"
     CDS_motif       255..383
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MDIVRSWKDADYRLSLGSEAPAHPSGEGLTAITDEELTEINGA"
                     /locus_tag="SSGG_RS13160_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       384..491
                     /prepeptide="core"
                     /locus_tag="SSGG_RS13160_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.00"
                     /molecular_weight="3443.0"
                     /monoisotopic_mass="3440.6"
                     /core_sequence="GSGVLGTLGCCSCLPWYSGWTVCGLACNPGKPCKN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDIVRSWKDADYRLSLGSEAPAHPSGEGLTAITDEELTEIN
                     GA"
                     /leader_location="[254:383](+)"
     gene            581..3895
                     /locus_tag="SSGG_RS13155"
                     /old_locus_tag="SSGG_04021"
     CDS             581..3895
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     953.5; E-value: 2.3e-288)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="SSGG_RS13155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSGG_04021"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_010071701.1"
                     /sec_met_domain="DUF4135 (E-value: 4.2e-92, bitscore:
                     297.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.8e-59, bitscore:
                     187.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDDASEHPTVRPAGAHLPWRRAATLSERLAGTPSQTDPVRGEKR
                     LAMWRELAPLTGELSTLDTRLEPLGVDTDRLTALLGEDDASLAARMADEPDWHRTFRRW
                     WAEGMATTDATRRLDPDMGLLEVIRPLVEGAVHELDALVEEAVRASDDPVMADPGHILD
                     IVRATAPAADLLSHVQRTLVLELNIARVEDRLVGETPEERFASYVELLRSEGNALAIWD
                     EYPVLARLIVGQLRFWIDTRAELITALVADLPVLRETLLAARPPQRLDRLEFGAGDKHR
                     RGRSVAMVEFDTCTLVFKPRSLAMDTAFDGLLAWVGRQNPTHDLARIGILERGDHGWVE
                     EVDTTATTDAAGGDRYAWRLGALTALLYLLHATDFHFENVLAAGEYPVLVDLEALLHND
                     KTAAVVKIDGETDIAAVTLADSVQSVGILPNHLLVRGEDGTFGLDVSGLAGHGGQLTPM
                     PVPIWEDSGTDRMRLVKRRMEMDAERNHPMTADGEPIDLVGRVDAFVEGFTHVYRLLET
                     GRDELLAPEGPLAAFGAVRTRLIARPTHIYGRLLLESTHPDFLRDGLDHARSLARLAGG
                     HVEMPESRNAMVLDEIAELTLGDIPMFTVDADSGTLRGGLDGEPIGTRYPPLTAVRERL
                     AALGDADLAFQERVIRSCVAATAMGESDARWPNWHRPRMDGAADPGDFADEALRLAHRL
                     ADLCVRDAHGLGWIGLDLVDEKYWQYAPAPIGLYTGTAGIAHALDAVAAVTGDERTGEL
                     ARAAFDQVAKRSVLIAETLAGLAKKPGADEFGIGAFGPFGGAIYALAHAAVRHDRPEYA
                     EAAATLLPAIDELVEEDPLLDIVSGSAGAILALLALETARPGTGAARIAERCAERLLAT
                     RQETADGWGWATPINPEQPLAGFSHGASGIAYAFARLDRVTPRAEYREAVRHALTYERT
                     VFDPELRTWRDLRPANLGGRTVMNAWCHGAPGIAMARNAFQELGTAPELADLIERDRHT
                     AVLAAISTGLDLDPVSGLGNHSLCHGDIGNLLIIDAATRADQEPEVAGLLPKVWKTLLH
                     EGRENGWLCGVPKGVETPGLMTGLAGIAWGLARKAAPERVPDLLTLAAPDTGRTTC"
     gene            4211..4402
                     /locus_tag="SSGG_RS37390"
                     /old_locus_tag="SSGG_04022"
     CDS             4211..4402
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSGG_RS37390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SSGG_04022"
                     /product="hypothetical protein"
                     /protein_id="WP_006126652.1"
                     /transl_table=11
                     /translation="MDGREVEGRVKDFRAGQGGARVTMVLVELPGGVAEELEEGASVVL
                     DQGTRPLLMDLWDERGDQ"
     gene            4399..6546
                     /locus_tag="SSGG_RS13150"
                     /old_locus_tag="SSGG_04023"
     CDS             4399..6546
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 310.1; E-value:
                     4.9e-94)"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.2"
                     /locus_tag="SSGG_RS13150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSGG_04023"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_010071703.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 9.5e-39, bitscore:
                     120.7, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIIRRRVPVRLQSTSVECGVAALAMVLGYHGRSTAVAELRDRMV
                     LSRDGASAASIARQARELGMKVRAFRAEPDALRDLALPLIAHWGMNHFVVIERFTRRGV
                     DIVDPASGRRHISHAELDASFTGVTLELEPTGELERRDGAETGLWSFVRPFLPRSVPIV
                     SAIIGASATLTLLGLLPAFLTAYVVDRVLPGRSEDTLLVLAAGLVAYTVSHALMTLARA
                     ELLLWLQTRMDWSMMGTFLRHLMSLPYKFFQLRTGGDLLVRVSSMTYVRDAVSSQLLAV
                     FLDVALLGVYLVVIGFKSLLFVAAILAVAAVQLGVMFASARAAQRLTERELQALGEAQS
                     TLLESVTGAETVKSSGAEHIVVRRWSRKFSEQLDASVRRSRLDNGIDSVLGMLGTASPL
                     LMLILGASLVFSDNLSLGTMLALIALAGAALAPVAQLGRSIKTFQTIRVHLDRLRDVLN
                     EPAESVGQGDAQVDLSEPITLTDVGFRYSGDGPEALSGISLTVRPGEKIAIVGSSGSGK
                     STLARLILGLYDPTDGEITYGSTPLTDLDLGHLRRQCGVVTQDADIFSGSVLTNIALVM
                     PEATLDDVVEAARLAAVHEDITHMPMGYETILGEGGNGLSGGQRQRVALARAVVHRPRV
                     LLLDEATSHLDATTEAIVHENLSELDCTRIVIAHRLSTVRDADRILVIDRGRIVEQGDH
                     DELVARNGAYAALVGQQLVHD"
ORIGIN
        1 atgaaccttg ttcgcgcatg gaaggacccc gagtaccggg ccaccctcag cgaggctccc
       61 gccaacccgg ccggcctcgt cgagctggcc gacgatcagc tcgacggtgt tgcgggcggg
      121 accacgtggg cgtgcgccac ggtcactctg accgtgacgg tgtgctcccc gaccgggacc
      181 ctctgcggca gctgcagcat gggcacgcgc ggctgttgct gagcctgccc cattcctgac
      241 aaggagttgt gtacatggac atagtccggt cctggaagga cgccgactac cggctgtccc
      301 tcgggagtga ggcccccgcc catccgtcgg gcgaaggcct caccgcaatc accgacgagg
      361 agctgaccga gatcaacgga gcgggctccg gcgttctcgg cactctcggg tgctgctcgt
      421 gcctgccgtg gtattcgggt tggaccgtct gcggtctcgc ctgcaacccc ggtaagccct
      481 gcaagaacta gcagcgtagc gaagaaacgg cgtgaccggc aggggcgggc gttcgtgcgc
      541 ccccgccggt catgtttcat gccccaggag gaagagcgga atgcctgacg acgcaagcga
      601 gcaccccacc gtccggccgg ccggggccca cctcccctgg cgccgggccg ccaccctgag
      661 cgaaagactc gccgggactc cgtcgcagac cgacccggta cggggcgaga agcgcctggc
      721 catgtggcgg gagctggcgc ccctgaccgg cgagctgtcc accctggaca cacggctgga
      781 accgctgggc gtcgacacgg accggctgac cgcgctgctc ggcgaggacg acgcgtccct
      841 cgccgcccgc atggcggacg aacccgactg gcaccgcacc ttccggcgct ggtgggccga
      901 gggcatggcc acgaccgacg ccacccgccg cctcgacccc gacatgggcc tcctggaagt
      961 gatccgcccc ctcgtggagg gcgccgtcca cgaactcgac gcgctcgtcg aggaagccgt
     1021 acgggccagc gacgaccccg tcatggccga ccccgggcac atcctcgaca tcgtccgcgc
     1081 gaccgccccg gccgccgacc tgctcagcca cgtccagcgg accctcgtcc tcgaactcaa
     1141 catcgcccgc gtcgaggacc gcctggtcgg cgagaccccc gaggaacgct tcgcctccta
     1201 cgtcgaactg ctgcgctcgg agggcaacgc cctcgccatc tgggacgaat acccggtact
     1261 ggcacggctg atcgtgggcc agctgcgctt ctggatcgac acccgggccg agctgatcac
     1321 ggccctcgtc gccgatctcc ccgtcctgcg cgagaccttg ctcgccgccc ggccgcccca
     1381 gcggctcgac cgcctggagt tcggcgccgg cgacaagcac cggcgcggcc ggtccgtcgc
     1441 catggtcgaa ttcgacacct gcaccctggt cttcaagccc cgttcgctgg ccatggacac
     1501 cgccttcgac ggactcctgg cctgggtcgg ccggcagaac cccacccacg acctggcccg
     1561 catcggcatc ctggagcgcg gcgaccacgg ctgggtcgag gaggtcgaca ccaccgcgac
     1621 caccgacgcc gccggcggcg accgctacgc ctggcggctg ggcgccctca ccgcgctcct
     1681 ctacctcctg cacgccacgg acttccactt cgagaacgtg ctggccgcgg gcgagtaccc
     1741 ggtcctcgtc gacctggaag cactgctcca caacgacaag accgccgccg tcgtcaagat
     1801 cgacggcgag accgacatag ccgcggtcac cctggccgac tccgtgcagt ccgtgggcat
     1861 cctgcccaac cacctgctgg tgcgcggcga ggacggcacc ttcggcctgg acgtcagcgg
     1921 actcgcgggc cacggcgggc agttgacccc catgccggtg ccgatctggg aggacagcgg
     1981 aaccgaccgc atgcggctgg tcaaacgccg catggagatg gacgccgagc gcaaccaccc
     2041 gatgaccgcc gacggcgaac cgatcgacct ggtcggccgg gtcgacgcgt tcgtcgaggg
     2101 gttcacccac gtctaccggc tgctggaaac gggacgcgac gaactgctgg cgcccgaagg
     2161 cccgttggcc gccttcggtg ccgtccggac ccggctcatc gcccggccga cccacatcta
     2221 cgggcgtctg ctgctggaga gcacccaccc ggacttcctg cgcgacggcc tcgaccacgc
     2281 gcgctcgctc gcccggctgg ccggcggcca cgtcgagatg cccgagtccc gcaacgcgat
     2341 ggtcctggac gagatcgccg agctcaccct cggcgacatc cccatgttca ccgtcgacgc
     2401 ggactccgga accctgcgcg gcggactgga cggcgagccg atcggcaccc gctacccgcc
     2461 cctcaccgcc gtacgggaac gcctcgcggc cctgggcgac gcggacctcg ccttccagga
     2521 gcgggtcatc cgctcgtgcg tcgcggccac cgccatgggc gagagcgacg cccgctggcc
     2581 caactggcac cggccccgga tggacggcgc cgccgacccc ggcgacttcg cggacgaggc
     2641 cctgcgcctg gcccaccggc tcgcggacct ctgcgtccgc gacgcacacg gcctcggctg
     2701 gatcgggctc gacctggtcg acgagaagta ctggcagtac gcgcccgccc cgatcggcct
     2761 ctacaccgga acggccggca tcgcgcacgc cctggacgcc gtcgcggccg tcaccggcga
     2821 cgagcggacc ggcgaactcg cccgggccgc cttcgaccag gtggcgaagc gctcagtgct
     2881 catcgccgag acactggcgg gcctggcgaa gaagccggga gccgacgagt tcggcatcgg
     2941 cgcgttcggc cccttcggcg gggcgatcta cgccctggcg cacgccgccg tacgccacga
     3001 ccgccccgaa tacgccgagg ccgccgccac gctgctgccc gccatcgacg aactcgtcga
     3061 ggaggacccg ctcctcgaca tcgtctccgg gtccgcgggc gcgatcctcg ccctcctcgc
     3121 cctggagacc gcccggcccg gcaccggagc ggcccggatc gcggaacgct gcgccgagcg
     3181 gctgctggcc acccggcagg agaccgccga cggctggggc tgggccactc cgatcaaccc
     3241 cgagcagccg ctcgccggct tctcgcacgg ggcctccggc atcgcgtacg cgttcgcgcg
     3301 cctcgaccgg gtcacacccc gcgcggagta cagggaagcc gtccggcacg cgctgacgta
     3361 cgagcggacc gtcttcgacc cggagctgcg cacctggcgc gacctgcggc cggccaacct
     3421 cggcggacgt acggtcatga acgcgtggtg ccacggggcc ccgggcatcg cgatggcccg
     3481 caacgcgttc caggagctgg gcaccgcacc ggagctggcc gacctcatcg agagggaccg
     3541 gcacacggcg gtcctcgccg ccatctcgac gggtctggac ctcgacccgg tgtcgggcct
     3601 cggcaaccac agcctgtgcc acggagacat cggcaacctc ctcatcatcg acgcggccac
     3661 ccgggccgac caggagccgg aagtcgccgg actgctgccc aaggtgtgga agacgctgct
     3721 gcacgagggc cgggagaacg gatggctgtg cggcgtcccc aagggtgtgg agacgcccgg
     3781 gctcatgacc ggtctggccg gcatcgcctg gggcctggcg cgcaaggccg cccccgagcg
     3841 ggtgccggac ctgctgacgc tggccgctcc ggacaccggg aggacgacgt gctgaacggc
     3901 gggcccgccc cggcggcccc gccggacggc gccatcgcgg acggcgtcta ccggccgagc
     3961 atggtcgccg cctaccgggc caacccgcgc ggcgccgccc gcaccggctt ccagcccgac
     4021 gcgatgcgcc cccgctggcg gtgggcgctg gccggagccc tgctgctggc cgccacggtg
     4081 gtcgcgggcc tcgtggtgcg ggtgccggtc ggtccgaccg gcaacctggc cggcaccgac
     4141 ggacgccaag gggtgctcgc cttcccggac ttcagcccac cggcgaagga cagcgacgtc
     4201 ctggctgagc gtggacggcc gagaggtgga gggccgggtg aaggacttcc gggccggcca
     4261 gggcggggct cgcgtcacca tggtcctcgt cgaactcccc ggcggcgtcg ccgaggaact
     4321 ggaggagggc gcgtccgtgg tcctcgacca gggcacccgc cccctgctca tggatctctg
     4381 ggacgaaagg ggcgaccagt gagcatcatc cgccgccgtg tgcccgtgcg gttgcagtcc
     4441 acctcggtcg agtgcggcgt cgccgccctc gccatggtgc tcggctacca cggccgctcc
     4501 accgccgtcg ccgagctgcg cgaccggatg gtgctgtccc gcgacggggc cagcgccgcg
     4561 tccatcgccc gccaggcacg cgaactcggc atgaaggtac gggccttccg cgccgaaccg
     4621 gacgcgctgc gcgatctggc cctgcccctg atcgcccact ggggcatgaa ccacttcgtc
     4681 gtcatcgagc ggttcacccg gcgcggggtc gacatcgtcg accccgcgtc cgggcggcgg
     4741 cacatcagcc acgcggagct ggacgcctcc ttcaccgggg tgacgctgga gctggaaccg
     4801 accggggaac tcgaacgccg cgacggcgcc gagacgggac tgtggtcctt cgtccgcccc
     4861 ttcctgcccc gctccgtgcc catcgtctcc gccatcatcg gcgcctccgc cacgctcacc
     4921 ctgctcgggc tgctcccggc cttcctgacg gcgtacgtcg tcgaccgcgt cctgcccggg
     4981 cgcagcgagg acaccctgct ggtcctggcg gccggtctcg tcgcctacac cgtcagccac
     5041 gccctgatga cgctggcccg ggcggagctg ctgctgtggc tccagacccg gatggactgg
     5101 tcgatgatgg ggacgttcct cagacatctg atgtccctgc cgtacaagtt cttccagctg
     5161 cgcaccggcg gcgacctgct cgtgcgggtg tcgagcatga cgtacgtccg ggacgccgtc
     5221 tccagccagc tcctggcggt cttcctcgac gtggccctgc tgggtgtcta cctcgtggtg
     5281 atcggcttca agtccctgct gttcgtcgcc gcgatcctcg cggtcgccgc cgtccagctc
     5341 ggggtcatgt tcgcttccgc ccgggccgcc cagcggctga ccgaacgcga actgcaggcg
     5401 ctcggagagg cccagagcac cctgctcgaa tcggtgaccg gcgccgagac ggtcaagtcc
     5461 tccggggccg aacacatcgt ggtgcgccgg tggtcgcgga agttctccga gcagctggac
     5521 gcctccgtac gccggagcag actcgacaac gggatcgaca gcgtcctcgg catgctgggc
     5581 accgcgtcgc cgctcctcat gctgattctc ggcgcctctc tcgtgttcag cgacaacctg
     5641 tcgctgggaa cgatgctcgc gctcatcgcc ctggccggcg cggcgctcgc cccggtcgcc
     5701 caactgggcc gcagcatcaa gacgttccag accatacggg tccacctcga ccggctccgc
     5761 gatgtgctga acgagccggc ggagtccgtg ggccaggggg acgcgcaggt ggacctgagc
     5821 gaaccgatca ccctgaccga cgtcggcttc cgctactccg gggacgggcc ggaggccctg
     5881 tcgggcatct ccctcaccgt ccggccgggc gagaagatcg ccattgtcgg cagcagcggt
     5941 tcggggaagt ccaccctggc ccgcctcatc ctcgggctct acgacccgac ggacggggag
     6001 atcacctacg gctccacccc gctgaccgac ctcgacctcg gccatctgcg ccgccagtgc
     6061 ggcgtcgtca cccaggatgc ggacatcttc agcggctcgg tactgaccaa catcgcgctg
     6121 gtcatgccgg aggccaccct cgacgacgtc gtcgaggccg cccggctcgc ggcggtccac
     6181 gaggacatca cccacatgcc gatggggtac gagacgatcc tcggcgaggg cggcaacggt
     6241 ctctccggcg ggcagcgcca gcgcgtggcc ctggcccgcg ccgtcgtgca ccggccgcgg
     6301 gtcctgctcc tcgacgaggc caccagccac ctggacgcca ccacggaggc gatcgtgcac
     6361 gagaacctct cggagctcga ctgcacccgc atcgtcatcg cgcaccgcct gagcaccgtc
     6421 cgggacgcgg accgcatcct ggtcatcgac cgcggccgga tcgtcgagca gggagaccac
     6481 gacgaactgg tcgccaggaa cggcgcgtac gcggcgctcg tcggccaaca actggtccat
     6541 gactga
//
