BGC0000555 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000555 (Staphylococcus aureus)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	lanthipeptide-class-ii	1	27,812	High	staphylococcin C55 α/staphylococcin C55 β	ribosomal:RiPP:Lanthipeptide

BGC0000555 - Region 1 - lanthipeptide-class-ii

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Location: 1 - 27,812 nt. (total: 27,812 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 27,813
Label		BGC0000555

Tailoring functions

Oxidoreductases: dehydrogenase

BAB78443.1: crotonyl-CoA reductase / alcohol dehydrogenase

smcogs: SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase

Lyases: cyclase

BAB78440.1: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

BAB78442.1: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000555.3	1.00	ribosomal	staphylococcin C55 α, staphylococcin C55 β	Staphylococcus aureus
BGC0000520.5	0.71	ribosomal	lacticin 3147 A1, lacticin 3147 A2	Lactococcus lactis
BGC0001229.4	0.63	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0002110.3	0.61	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0000623.3	0.53	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000539.5	0.53	ribosomal	nukacin ISK-1	Staphylococcus warneri
BGC0000497.3	0.52	ribosomal	BHT-Aα, BHT-Aβ	Streptococcus ratti
BGC0001391.3	0.52	ribosomal	thusin	Bacillus thuringiensis serovar rongseni
BGC0000517.4	0.51	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0001555.4	0.51	ribosomal	colicin V	Escherichia coli chi7122

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000555.3	1.00	ribosomal	staphylococcin C55 α, staphylococcin C55 β	Staphylococcus aureus
BGC0000520.5	0.71	ribosomal	lacticin 3147 A1, lacticin 3147 A2	Lactococcus lactis
BGC0001229.4	0.63	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0002110.3	0.61	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0000623.3	0.53	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000539.5	0.53	ribosomal	nukacin ISK-1	Staphylococcus warneri
BGC0000497.3	0.52	ribosomal	BHT-Aα, BHT-Aβ	Streptococcus ratti
BGC0001391.3	0.52	ribosomal	thusin	Bacillus thuringiensis serovar rongseni
BGC0000517.4	0.51	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0001555.4	0.51	ribosomal	colicin V	Escherichia coli chi7122

Similar known clusters from MIBiG 4.0

Lanthipeptide predictions

Lanthipeptide(s) for BAB78440.1

BAB78438.1

Leader:

MKSSFLEKDIEEQVTWFEEVSEQEFDDDIFGA

Core:

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

Core with dehydrations:

CysDhaDhbNDhbFDhaLDhaDYWGNKGNWCysDhbADhbHECysMDhaWCysK

antiSMASH-DB 4.0 matches for BAB78438.1

93.3%

NZ_AP026714.1and 21 others:

NZ_AP026714.1 Lanthipeptides: PO853_RS06515_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide

Lanthipeptides: PO853_RS06515_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

C+TNTFSLSDYWGNKGNWCTATHECM WCK

CTTNTFSLSDYWGNKGNWCTATHECMGWCK

93.3%

NZ_CP061868.1and 1 other:

NZ_CP061868.1 Lanthipeptides: IE339_RS06330_lanthipeptide

Lanthipeptides: IE339_RS06330_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

C+TNTFSLSDYWGNKG WCTATHECMSWCK

CTTNTFSLSDYWGNKGGWCTATHECMSWCK

93.3%

NZ_FMPI01000012.1and 1 other:

NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08305_lanthipeptide

Lanthipeptides: BJR39_RS08305_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDYWGN GNWCTA+HECMSWCK

CSTNTFSLSDYWGNNGNWCTASHECMSWCK

with 106 more sequence matches

Only the first 10 are displayed here.

93.3%

NZ_PCGR01000003.1and 1 other:

NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09620_lanthipeptide

Lanthipeptides: CQS04_RS09620_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

C+TNTFSLSDYWGN GNWCTATHECMSWCK

CTTNTFSLSDYWGNNGNWCTATHECMSWCK

90.0%

NZ_BLIS01000009.1and 7 others:

NZ_BLIS01000009.1 Lanthipeptides: GVO03_RS04820_lanthipeptideNZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptideNZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptideNZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptideNZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptideNZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptideNZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide

Lanthipeptides: GVO03_RS04820_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

C+TNTFSLSDYWGNKGNWCT THECM+WCK

CTTNTFSLSDYWGNKGNWCTLTHECMNWCK

90.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0097945_0098112_lanthipeptide

Lanthipeptides: allorf_0097945_0098112_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDYWGN+G WCT THECMSWCK

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

90.0%

NZ_CP034414.1and 1 other:

NZ_CP034414.1 Lanthipeptides: EI692_RS18440_lanthipeptide

Lanthipeptides: EI692_RS18440_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDYWGNKG WCT +HECMSWCK

CSTNTFSLSDYWGNKGGWCTISHECMSWCK

86.7%

NZ_CACZYW010000004.1and 1 other:

NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02825_lanthipeptide

Lanthipeptides: HUF10_RS02825_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDYWGN GNWCT +HECM+WCK

CSTNTFSLSDYWGNNGNWCTLSHECMAWCK

86.7%

NZ_CP051884.1and 2 others:

NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptideNZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide

Lanthipeptides: HGK68_RS15125_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDYWGN G CT THECMSWCK

CSTNTFSLSDYWGNNGWLCTITHECMSWCK

86.7%

NZ_NUIO01000031.1and 1 other:

NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23160_lanthipeptide

Lanthipeptides: CN977_RS23160_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

C+TNTFSLSDYWGN G+WCTATHEC+SWCK

CTTNTFSLSDYWGNDGSWCTATHECLSWCK

86.7%

NZ_QGEE01000020.1and 5 others:

NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06160_lanthipeptideNZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptideNZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptideNZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptideNZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide

Lanthipeptides: DKP74_RS06160_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDYWGN+GNWCT +HECM+WCK

CSTNTFSLSDYWGNRGNWCTLSHECMAWCK

83.3%

NZ_FNHR01000005.1and 1 other:

NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05590_lanthipeptide

Lanthipeptides: BLQ37_RS05590_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDY GN GNWCT +HECM+WCK

CSTNTFSLSDYMGNNGNWCTISHECMAWCK

80.0%

NZ_MIFN01000022.1and 1 other:

NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15350_lanthipeptide

Lanthipeptides: BHL26_RS15350_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

C+TNTFSLSDYWGN G+WC+ +HECMSWCK

CTTNTFSLSDYWGNDGSWCSLSHECMSWCK

MIBiG 4.0 matches for BAB78438.1

60.0%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

CSTNTFSLSDYWGNKGNWCTATHECMSWC

C+TNTFSLS+ GN G WCT T EC C

CTTNTFSLSNALGNNGGWCTLTKECQPNC

40.0%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

FSLSDYWGNKGNWCTATHECMSWC

+++S GNKG +CT T ECM C

YNISCRLGNKGAYCTLTVECMPSC

12.8%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTATHECMSWC

CT + EC C

CTLSKECQPNC

BAB78439.1

Leader:

MKNELGKFLEENELELGKFSESDMLEITDDEVYAA

Core:

GTPLALLGGAATGVIGYISNQTCPTTACTRAC

Core with dehydrations:

GDhbPLALLGGAADhbGVIGYIDhaNQDhbCysPDhbDhbACysDhbRACys

antiSMASH-DB 4.0 matches for BAB78439.1

78.1%

NZ_FMPI01000012.1and 1 other:

NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08310_lanthipeptide

Lanthipeptides: BJR39_RS08310_lanthipeptide

GTPLALLGGAATGVIGYISNQTCPTTACTRAC

TP ALL GAA GV+ Y+SNQTCPTTACTRAC

ATPTALLAGAAGGVVTYVSNQTCPTTACTRAC

56.2%

NZ_NUIO01000031.1and 1 other:

NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23165_lanthipeptide

Lanthipeptides: CN977_RS23165_lanthipeptide

AATGVIGYISNQTCPTTACTRAC

A T V GYIS+ TCPTTACTRAC

ALTAVSGYISSNTCPTTACTRAC

54.5%

NZ_MIFN01000022.1and 1 other:

NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide

Lanthipeptides: BHL26_RS15355_lanthipeptide

GAATGVIGYISNQTCPTTACTRAC

GA T V GYIS+ TCP+TACTRAC

GALTAVSGYISSNTCPSTACTRAC

with 81 more sequence matches

Only the first 10 are displayed here.

53.1%

NZ_CP051884.1and 3 others:

NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptideNZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptideNZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide

Lanthipeptides: HGK68_RS15130_lanthipeptide

GTPLALLGGAATGVIGYISNQTCPTTACTRAC

GTP +L + V +ISN TCP++ACTRAC

GTPTVVL----SIVSAWISNNTCPSSACTRAC

50.0%

NZ_CP016767.1and 3 others:

NZ_CP016767.1 Lanthipeptides: BCV50_RS13415_lanthipeptideNZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptideNZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide

Lanthipeptides: BCV50_RS13415_lanthipeptide

AATGVIGYISNQTCPTTACTRAC

A + + GYIS+ TCPTTACTRAC

ALSVITGYISSNTCPTTACTRAC

50.0%

NZ_CP061868.1and 1 other:

NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide

Lanthipeptides: IE339_RS06335_lanthipeptide

TGVIGYISNQTCPTTACTRAC

T V GYIS TCPTT+CTRAC

TAVTGYISTNTCPTTSCTRAC

50.0%

NZ_JALAPU010000003.1and 7 others:

NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07925_lanthipeptideNZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00585_lanthipeptideNZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00585_lanthipeptideNZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17010_lanthipeptideNZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17010_lanthipeptideNZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04640_lanthipeptideNZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04640_lanthipeptide

Lanthipeptides: MOD17_RS07925_lanthipeptide

AATGVIGYISNQTCPTTACTRAC

A + V YIS+ TCPTTACTRAC

ALSVVTAYISSNTCPTTACTRAC

50.0%

NZ_QGEE01000020.1and 3 others:

NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06165_lanthipeptideNZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptideNZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptide

Lanthipeptides: DKP74_RS06165_lanthipeptide

LLGGAATGVIGYISNQTCPTTACTRAC

++G +A V G++S+ TCPTTACTRAC

VIGYSAVIVSGFVSSHTCPTTACTRAC

46.9%

NZ_PCGR01000003.1and 1 other:

NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide

Lanthipeptides: CQS04_RS09625_lanthipeptide

TGVIGYISNQTCPTTACTRAC

T + GYIS +CPTTACTRAC

TAITGYISANSCPTTACTRAC

45.5%

NZ_LR134317.1and 1 other:

NZ_LR134317.1 Lanthipeptides: EL136_RS01690_lanthipeptide

Lanthipeptides: EL136_RS01690_lanthipeptide

LLGGAATGVIGYISNQTCPTTACTRAC

L A+ V +IS TCPTT+CTRAC

WLVKASVAVTAFISANTCPTTSCTRAC

43.8%

NZ_CACZYW010000004.1and 3 others:

NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02820_lanthipeptideNZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptideNZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide

Lanthipeptides: HUF10_RS02820_lanthipeptide

GVIGYISNQTCPTTACTRAC

V Y+S++TCPTTACTRAC

AVSAYVSDKTCPTTACTRAC

43.8%

NZ_CP034414.1and 1 other:

NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide

Lanthipeptides: EI692_RS18435_lanthipeptide

VIGYISNQTCPTTACTRAC

V G+IS TCP+TACTRAC

VSGFISTNTCPSTACTRAC

40.6%

NZ_AP026714.1and 21 others:

NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide

Lanthipeptides: PO853_RS06520_lanthipeptide

GVIGYISNQTCPTTACTRAC

V G+IS++TCPT+ CTRAC

AVSGWISDKTCPTSVCTRAC

MIBiG 4.0 matches for BAB78439.1

35.1%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

LALLGGAATGVIGYISNQTCPTTACTRAC

+A+ G A GV S CPTT CT C

VAIQAGVAVGV----SAAFCPTTKCTSRC

21.9%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

CPTTACTRAC

CPTT CT C

CPTTKCTSKC

BAB78446.1

Leader:

MSALNWFILFVISAMLGSFAASILDNIMQS

Core:

IWIPRICGGLVAALVGGFLYLFFTNEK

Core with dehydrations:

IWIPRICysGGLVAALVGGFLYLFFDhbNEK

antiSMASH-DB 4.0 matches for BAB78446.1

88.9%

NZ_FMPI01000012.1and 1 other:

NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS13940_lanthipeptide

Lanthipeptides: BJR39_RS13940_lanthipeptide

IWIPRICGGLVAALVGGFLYLFFTNEK

IWIPRICGGLVAALVG LYL+FTNEK

IWIPRICGGLVAALVGFCLYLYFTNEK

18.5%

NZ_CP064879.1:

Lanthipeptides: allorf_8092967_8093083_lanthipeptide

WIPRICGGLVAALVGGF

+IP+IC ++++ F

FIPQICNANFSSVITPF

13.9%

NZ_CP077726.1:

Lanthipeptides: allorf_54450_54584_lanthipeptide

IWIPRICGGLVAAL

+++PR C A L

VYVPRTCPSKFAIL

with 2 more sequence matches

13.0%

NZ_CP041405.1:

Lanthipeptides: FLT43_RS14400_lanthipeptide

RICGGLVAALVGGF

++C LVA+ +GG

KVCLSLVASAIGGI

10.3%

NZ_CP019687.1:

Lanthipeptides: BXP28_RS22835_lanthipeptide

WIPRIC

W PR+C

WFPRMC

allorf_02957_03112

Leader:

MYIHRWYNNRVAYLSGVNRRREEVHYF

Core:

ANHFRSHHSTSHQWLCCCVLYLLA

Core with dehydrations:

ANHFRDhaHHDhaDhbDhaHQWLCysCysCysVLYLLA

antiSMASH-DB 4.0 matches for allorf_02957_03112

29.2%

NZ_JAQCXO010000012.1:

Lanthipeptides: allorf_079305_079412_lanthipeptide

SHHSTSHQWLCCC

S +S H+WL CC

SLNSEIHKWLSCC

25.0%

NZ_JAASAG010000001.1:

Lanthipeptides: allorf_346005_346232_lanthipeptide

NHFRSHHSTSHQ

+ R+HH TS Q

DRARAHHGTSEQ

21.3%

NZ_JACHIP010000018.1:

Lanthipeptides: allorf_31884_32123_lanthipeptide

STSHQWLCCCVLYLL

S+SHQW CC LY L

SSSHQW--CCYLYWL

allorf_03153_03335

Leader:

MFFIVLRQKKKRSSKSSPKFINLKKNGVITSEYYNLLKNRFKNTLKGA

Core:

LKICKTLIYLFR

Core with dehydrations:

LKICysKDhbLIYLFR

allorf_03364_03504

Leader:

MTVYPVVPPKVDYRLTEIGLKLDKVVFS

Core:

ICDWDDDFLDTVKINNHR

Core with dehydrations:

ICysDWDDDFLDDhbVKINNHR

antiSMASH-DB 4.0 matches for allorf_03364_03504

12.8%

NZ_AP014703.1and 5 others:

NZ_CP031648.1 Lanthipeptides: allorf_4585502_4585645_lanthipeptideNZ_CP048810.1 Lanthipeptides: allorf_5138083_5138226_lanthipeptideNZ_CP097108.1 Lanthipeptides: M3M50_RS26390_lanthipeptideNZ_JAJQKS010000013.1 Lanthipeptides: LT249_RS28345_lanthipeptideNZ_QGDM01000020.1 Lanthipeptides: allorf_094784_094927_lanthipeptide

Lanthipeptides: allorf_5838294_5838437_lanthipeptide

DWDDDFLDTVKINN

D+D DF+ ++N+

DFDGDFMSYRQVNS

MIBiG 4.0 matches for allorf_03364_03504

12.8%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

LDTVKI

+DTVKI

IDTVKI

allorf_04427_04519

Leader:

MNVFTNYNELYKKNGS

Core:

VAKLKNKCLTLCLK

Core with dehydrations:

VAKLKNKCysLDhbLCysLK

Lanthipeptide(s) for BAB78442.1

BAB78438.1

Leader:

MKSSFLEKDIEEQVTWFEEVSEQEFDDDIFGA

Core:

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

Core with dehydrations:

CysDhaDhbNDhbFDhaLDhaDYWGNKGNWCysDhbADhbHECysMDhaWCysK

antiSMASH-DB 4.0 matches for BAB78438.1

93.3%

NZ_AP026714.1and 21 others:

Lanthipeptides: PO853_RS06515_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

C+TNTFSLSDYWGNKGNWCTATHECM WCK

CTTNTFSLSDYWGNKGNWCTATHECMGWCK

93.3%

NZ_CP061868.1and 1 other:

NZ_CP061868.1 Lanthipeptides: IE339_RS06330_lanthipeptide

Lanthipeptides: IE339_RS06330_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

C+TNTFSLSDYWGNKG WCTATHECMSWCK

CTTNTFSLSDYWGNKGGWCTATHECMSWCK

93.3%

NZ_FMPI01000012.1and 1 other:

NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08305_lanthipeptide

Lanthipeptides: BJR39_RS08305_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDYWGN GNWCTA+HECMSWCK

CSTNTFSLSDYWGNNGNWCTASHECMSWCK

with 106 more sequence matches

Only the first 10 are displayed here.

93.3%

NZ_PCGR01000003.1and 1 other:

NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09620_lanthipeptide

Lanthipeptides: CQS04_RS09620_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

C+TNTFSLSDYWGN GNWCTATHECMSWCK

CTTNTFSLSDYWGNNGNWCTATHECMSWCK

90.0%

NZ_BLIS01000009.1and 7 others:

Lanthipeptides: GVO03_RS04820_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

C+TNTFSLSDYWGNKGNWCT THECM+WCK

CTTNTFSLSDYWGNKGNWCTLTHECMNWCK

90.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0097945_0098112_lanthipeptide

Lanthipeptides: allorf_0097945_0098112_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDYWGN+G WCT THECMSWCK

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

90.0%

NZ_CP034414.1and 1 other:

NZ_CP034414.1 Lanthipeptides: EI692_RS18440_lanthipeptide

Lanthipeptides: EI692_RS18440_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDYWGNKG WCT +HECMSWCK

CSTNTFSLSDYWGNKGGWCTISHECMSWCK

86.7%

NZ_CACZYW010000004.1and 1 other:

NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02825_lanthipeptide

Lanthipeptides: HUF10_RS02825_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDYWGN GNWCT +HECM+WCK

CSTNTFSLSDYWGNNGNWCTLSHECMAWCK

86.7%

NZ_CP051884.1and 2 others:

NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptideNZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide

Lanthipeptides: HGK68_RS15125_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDYWGN G CT THECMSWCK

CSTNTFSLSDYWGNNGWLCTITHECMSWCK

86.7%

NZ_NUIO01000031.1and 1 other:

NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23160_lanthipeptide

Lanthipeptides: CN977_RS23160_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

C+TNTFSLSDYWGN G+WCTATHEC+SWCK

CTTNTFSLSDYWGNDGSWCTATHECLSWCK

86.7%

NZ_QGEE01000020.1and 5 others:

Lanthipeptides: DKP74_RS06160_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDYWGN+GNWCT +HECM+WCK

CSTNTFSLSDYWGNRGNWCTLSHECMAWCK

83.3%

NZ_FNHR01000005.1and 1 other:

NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05590_lanthipeptide

Lanthipeptides: BLQ37_RS05590_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

CSTNTFSLSDY GN GNWCT +HECM+WCK

CSTNTFSLSDYMGNNGNWCTISHECMAWCK

80.0%

NZ_MIFN01000022.1and 1 other:

NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15350_lanthipeptide

Lanthipeptides: BHL26_RS15350_lanthipeptide

CSTNTFSLSDYWGNKGNWCTATHECMSWCK

C+TNTFSLSDYWGN G+WC+ +HECMSWCK

CTTNTFSLSDYWGNDGSWCSLSHECMSWCK

MIBiG 4.0 matches for BAB78438.1

60.0%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

CSTNTFSLSDYWGNKGNWCTATHECMSWC

C+TNTFSLS+ GN G WCT T EC C

CTTNTFSLSNALGNNGGWCTLTKECQPNC

40.0%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

FSLSDYWGNKGNWCTATHECMSWC

+++S GNKG +CT T ECM C

YNISCRLGNKGAYCTLTVECMPSC

12.8%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTATHECMSWC

CT + EC C

CTLSKECQPNC

BAB78439.1

Leader:

MKNELGKFLEENELELGKFSESDMLEITDDEVYAA

Core:

GTPLALLGGAATGVIGYISNQTCPTTACTRAC

Core with dehydrations:

GDhbPLALLGGAADhbGVIGYIDhaNQDhbCysPDhbDhbACysDhbRACys

antiSMASH-DB 4.0 matches for BAB78439.1

78.1%

NZ_FMPI01000012.1and 1 other:

NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08310_lanthipeptide

Lanthipeptides: BJR39_RS08310_lanthipeptide

GTPLALLGGAATGVIGYISNQTCPTTACTRAC

TP ALL GAA GV+ Y+SNQTCPTTACTRAC

ATPTALLAGAAGGVVTYVSNQTCPTTACTRAC

56.2%

NZ_NUIO01000031.1and 1 other:

NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23165_lanthipeptide

Lanthipeptides: CN977_RS23165_lanthipeptide

AATGVIGYISNQTCPTTACTRAC

A T V GYIS+ TCPTTACTRAC

ALTAVSGYISSNTCPTTACTRAC

54.5%

NZ_MIFN01000022.1and 1 other:

NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide

Lanthipeptides: BHL26_RS15355_lanthipeptide

GAATGVIGYISNQTCPTTACTRAC

GA T V GYIS+ TCP+TACTRAC

GALTAVSGYISSNTCPSTACTRAC

with 81 more sequence matches

Only the first 10 are displayed here.

53.1%

NZ_CP051884.1and 3 others:

NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptideNZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptideNZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide

Lanthipeptides: HGK68_RS15130_lanthipeptide

GTPLALLGGAATGVIGYISNQTCPTTACTRAC

GTP +L + V +ISN TCP++ACTRAC

GTPTVVL----SIVSAWISNNTCPSSACTRAC

50.0%

NZ_CP016767.1and 3 others:

NZ_CP016767.1 Lanthipeptides: BCV50_RS13415_lanthipeptideNZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptideNZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide

Lanthipeptides: BCV50_RS13415_lanthipeptide

AATGVIGYISNQTCPTTACTRAC

A + + GYIS+ TCPTTACTRAC

ALSVITGYISSNTCPTTACTRAC

50.0%

NZ_CP061868.1and 1 other:

NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide

Lanthipeptides: IE339_RS06335_lanthipeptide

TGVIGYISNQTCPTTACTRAC

T V GYIS TCPTT+CTRAC

TAVTGYISTNTCPTTSCTRAC

50.0%

NZ_JALAPU010000003.1and 7 others:

Lanthipeptides: MOD17_RS07925_lanthipeptide

AATGVIGYISNQTCPTTACTRAC

A + V YIS+ TCPTTACTRAC

ALSVVTAYISSNTCPTTACTRAC

50.0%

NZ_QGEE01000020.1and 3 others:

NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06165_lanthipeptideNZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptideNZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptide

Lanthipeptides: DKP74_RS06165_lanthipeptide

LLGGAATGVIGYISNQTCPTTACTRAC

++G +A V G++S+ TCPTTACTRAC

VIGYSAVIVSGFVSSHTCPTTACTRAC

46.9%

NZ_PCGR01000003.1and 1 other:

NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide

Lanthipeptides: CQS04_RS09625_lanthipeptide

TGVIGYISNQTCPTTACTRAC

T + GYIS +CPTTACTRAC

TAITGYISANSCPTTACTRAC

45.5%

NZ_LR134317.1and 1 other:

NZ_LR134317.1 Lanthipeptides: EL136_RS01690_lanthipeptide

Lanthipeptides: EL136_RS01690_lanthipeptide

LLGGAATGVIGYISNQTCPTTACTRAC

L A+ V +IS TCPTT+CTRAC

WLVKASVAVTAFISANTCPTTSCTRAC

43.8%

NZ_CACZYW010000004.1and 3 others:

NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02820_lanthipeptideNZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptideNZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide

Lanthipeptides: HUF10_RS02820_lanthipeptide

GVIGYISNQTCPTTACTRAC

V Y+S++TCPTTACTRAC

AVSAYVSDKTCPTTACTRAC

43.8%

NZ_CP034414.1and 1 other:

NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide

Lanthipeptides: EI692_RS18435_lanthipeptide

VIGYISNQTCPTTACTRAC

V G+IS TCP+TACTRAC

VSGFISTNTCPSTACTRAC

40.6%

NZ_AP026714.1and 21 others:

Lanthipeptides: PO853_RS06520_lanthipeptide

GVIGYISNQTCPTTACTRAC

V G+IS++TCPT+ CTRAC

AVSGWISDKTCPTSVCTRAC

MIBiG 4.0 matches for BAB78439.1

35.1%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

LALLGGAATGVIGYISNQTCPTTACTRAC

+A+ G A GV S CPTT CT C

VAIQAGVAVGV----SAAFCPTTKCTSRC

21.9%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

CPTTACTRAC

CPTT CT C

CPTTKCTSKC

BAB78446.1

Leader:

MSALNWFILFVISAMLGSFAASILDNIMQS

Core:

IWIPRICGGLVAALVGGFLYLFFTNEK

Core with dehydrations:

IWIPRICysGGLVAALVGGFLYLFFDhbNEK

antiSMASH-DB 4.0 matches for BAB78446.1

88.9%

NZ_FMPI01000012.1and 1 other:

NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS13940_lanthipeptide

Lanthipeptides: BJR39_RS13940_lanthipeptide

IWIPRICGGLVAALVGGFLYLFFTNEK

IWIPRICGGLVAALVG LYL+FTNEK

IWIPRICGGLVAALVGFCLYLYFTNEK

18.5%

NZ_CP064879.1:

Lanthipeptides: allorf_8092967_8093083_lanthipeptide

WIPRICGGLVAALVGGF

+IP+IC ++++ F

FIPQICNANFSSVITPF

13.9%

NZ_CP077726.1:

Lanthipeptides: allorf_54450_54584_lanthipeptide

IWIPRICGGLVAAL

+++PR C A L

VYVPRTCPSKFAIL

with 2 more sequence matches

13.0%

NZ_CP041405.1:

Lanthipeptides: FLT43_RS14400_lanthipeptide

RICGGLVAALVGGF

++C LVA+ +GG

KVCLSLVASAIGGI

10.3%

NZ_CP019687.1:

Lanthipeptides: BXP28_RS22835_lanthipeptide

WIPRIC

W PR+C

WFPRMC

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

BAB78438.1 - Class II

Cleavage pHMM score: 2.20

RODEO score: 0

Monoisotopic mass: 3315.4 Da

Molecular weight: 3317.7 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3335.7 Da N = 1; 3353.7 Da N = 2; 3371.7 Da N = 3; 3389.7 Da N = 4

BAB78439.1 - Class II

Cleavage pHMM score: -1.70

RODEO score: 0

Monoisotopic mass: 2954.5 Da

Molecular weight: 2956.4 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2974.4 Da N = 1; 2992.4 Da N = 2; 3010.5 Da N = 3; 3028.5 Da N = 4

BAB78446.1 - Class II

Cleavage pHMM score: -6.50

RODEO score: 0

Monoisotopic mass: 2978.6 Da

Molecular weight: 2980.6 Da

Number of bridges: 1

allorf_02957_03112 - Class II

Cleavage pHMM score: -6.00

RODEO score: 0

Monoisotopic mass: 2753.3 Da

Molecular weight: 2755.1 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2773.2 Da N = 1

allorf_03153_03335 - Class II

Cleavage pHMM score: -3.90

RODEO score: 0

Monoisotopic mass: 1491.9 Da

Molecular weight: 1492.9 Da

Number of bridges: 1

allorf_03364_03504 - Class II

Cleavage pHMM score: -4.20

RODEO score: 0

Monoisotopic mass: 2200.0 Da

Molecular weight: 2201.4 Da

Number of bridges: 1

allorf_04427_04519 - Class II

Cleavage pHMM score: -6.00

RODEO score: 0

Monoisotopic mass: 1555.9 Da

Molecular weight: 1557.0 Da

Number of bridges: 1

BAB78438.1 - Class II

Cleavage pHMM score: 2.20

RODEO score: 0

Monoisotopic mass: 3315.4 Da

Molecular weight: 3317.7 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3335.7 Da N = 1; 3353.7 Da N = 2; 3371.7 Da N = 3; 3389.7 Da N = 4

BAB78439.1 - Class II

Cleavage pHMM score: -1.70

RODEO score: 0

Monoisotopic mass: 2954.5 Da

Molecular weight: 2956.4 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2974.4 Da N = 1; 2992.4 Da N = 2; 3010.5 Da N = 3; 3028.5 Da N = 4

BAB78446.1 - Class II

Cleavage pHMM score: -6.50

RODEO score: 0

Monoisotopic mass: 2978.6 Da

Molecular weight: 2980.6 Da

Number of bridges: 1