Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000557.1:
Cluster 1RiPP111650

BGC0000557, streptococcin A-FF22 biosynthetic gene cluster from Streptococcus pyogenes. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: streptococcin A-FF22

Class-specific details

Biosynthetic class(es):
RiPP
RiPP subclass:
Lanthipeptide

Gene cluster description

streptococcin A-FF22 (BGC0000557). Gene Cluster 1. Biosynthetic class = RiPP. GenBank AF026542. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

scnA leader / core peptide, putative Class II
MEKNNEVINSIQEVSLEELDQIIGA - GKNGVFKDhbIDhaHECHLNDhbWAFLADhbCCDha
scnA1 leader / core peptide, putative Class II
MEEKMCLGALNALQEFQIEELDNLLGG - RGHGVNDhbIDhaAECRWNDhaLQAIFDhbCC

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Homologous known gene clusters

Literature references

1. Hynes WL et al. (1993) Cloning of the gene encoding Streptococcin A-FF22, a novel lantibiotic produced by Streptococcus pyogenes, and determination of its nucleotide sequence. Appl Environ Microbiol 59(6):1969-71.
2. Natsiuk MV, Chekman IS. (1975) [Level of nicotinamide coenzymes in the liver and myocardium of rats poisoned with dichlorethane]. Biull Eksp Biol Med 79(4):58-60.