LOCUS       BGC0000558              5203 bp    DNA     linear   BCT 08-OCT-1998
DEFINITION  Bacillus subtilis uvr repair protein (uvrX), sublancin 168 precursor
            peptide (sunA), and sublancin transporter protein (sunT) genes,
            complete cds.
ACCESSION   BGC0000558
VERSION     BGC0000558
KEYWORDS    .
SOURCE      Bacillus subtilis subsp. subtilis str. 168
  ORGANISM  Bacillus subtilis subsp. subtilis str. 168
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
COMMENT     On Oct 9, 1998 this sequence version replaced gi:2343276.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:50:29
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5203
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..5203
                     /db_xref="taxon:224308"
                     /mol_type="genomic DNA"
                     /organism="Bacillus subtilis subsp. subtilis str. 168"
                     /strain="168"
                     /sub_species="subtilis"
                     /type_material="type strain of Bacillus subtilis"
     protocluster    1..5203
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2821:2992]"
                     /cutoff="20000"
                     /detection_rule="(glycocin or sublancin)"
                     /neighbourhood="10000"
                     /product="glycocin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2822..2992
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(glycocin or sublancin)"
                     /neighbourhood="10000"
                     /product="glycocin"
                     /protocluster_number="1"
     cand_cluster    1..5203
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(glycocin or sublancin)"
                     /kind="single"
                     /product="glycocin"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..5203
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000558"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..5203
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="glycocin"
                     /region_number="1"
                     /rules="(glycocin or sublancin)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            857..1855
                     /gene="uvrX"
     CDS             857..1855
                     /codon_start=1
                     /gene="uvrX"
                     /product="uvr repair protein"
                     /protein_id="AAC63530.1"
                     /transl_table=11
                     /translation="MIDYSQFPRKNILCVDMKSFYASVSAVTMGLNPLTCYLAVVGNTE
                     RQGSVVLAASPALKKDFGIKTGSRLFEIPEDPRIHIVNPQMKLFIRVSTEITKLFYRFV
                     PEKCVHTYSIDESFLDAGKEDPEEMAKAIQSSMWREFGLMCTVGIGDNMLLSKLALDLE
                     SKKTKSGIARWRYEDVPNKLWKVRPLSKMWGIGGRMERNLNRMGISTIGQLAKFPLELL
                     EKKFGIMGNQLYYHAHGIDLSEIGAPLMQGQISFGKSQILLRDYTRSEEIKAVLLEICE
                     EVARRHVHIIKLVEQSVWELGTVRMSLVVVFIVPKQLIFLQVSRWIFIDAA"
     gene            2822..2992
                     /gene="sunA"
     CDS             2822..2992
                     /codon_start=1
                     /gene="sunA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     glycocin: sublancin"
                     /gene_kind="biosynthetic"
                     /note="lantibiotic antimicrobial peptide; SunA"
                     /product="sublancin 168 precursor peptide"
                     /protein_id="AAC63531.1"
                     /sec_met_domain="sublancin (E-value: 1.2e-46, bitscore:
                     144.6, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLFKEVKLEELENQKGSGLGKAQCAALWLQCASGGTIGCGGGA
                     VACQNYRQFCR"
     gene            3044..5167
                     /gene="sunT"
     CDS             3044..5167
                     /codon_start=1
                     /gene="sunT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 196.7; E-value:
                     1.2e-59)"
                     /gene_kind="transport"
                     /note="lantibiotic transporter protein; SunT"
                     /product="sublancin transporter protein"
                     /protein_id="AAC63532.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.4e-37, bitscore:
                     114.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLNKKKKYVHTKQFNSHDCGLACISSILKFHNLNYGIDFLLDLI
                     GDKEGYSLRDLIVIFKKMGIKTRPLELQENKTFEALKQIKLPCIALLEGEEYGHYITIY
                     EIRNNYLLVSDPDKDKITKIKKEDFESKFTNFILEIDKESIPEKEKDQKKHSYFFKDIL
                     FRNKLIVFVILLTSLFVVGLAVAGSFYIKFLVDLIIPRSLRESLITITLIFISMVLIRC
                     IFDFVRSYLIIKLSYKVDKEMSNVYFNKVTKLPINFFENREDGEVISRFNDGIYIKDFF
                     SANFVTAIIDIILILGLGVILYRTNNILFLTIILPILLLSCLAILFFDHLKKKNQKLME
                     DKAKSTSLLINFLKNMTTVYSLNKTSFFLEKFHLTYDKQLNSTFSVAKAVISNEILKGL
                     IQNSFTIIILWVGTRQVLNDSMSLGTLLFINTLAAFLLSSLDRILSMQSDLQQAHVASI
                     RFFDVVNYPVQQDSNENLTELDFIQNIKTVNLNIGADPMRYIVEDINLILDRKDKVLII
                     GESGTGKSTFAKSLSKLYKVPDKSIYLNGLDINRYDHLSIRKRIVYIDENPFLFKGTIK
                     ENLCMGEIFDQNEIENACIMSQCHEFICNLDKQYSYKLSENGSNLSTGQKQRLALARAI
                     LHQPQVLILDESLSNIDPDNTKLIYETLHRMDCLIILITHNDPSNFKYNKKLVFRNNRI
                     IESSYSENKEYSI"
ORIGIN
        1 gcttaaataa agagctgggc attttactta ttggggttat ttgctttcaa atacctcgat
       61 gttctttctc caatttatta atatcatctt ttaatatata gatcttatat ttttcctttg
      121 cttctctaga cagattatct tttaaatact cacggagctt tgcttcactt ttggtttgat
      181 ccatgccaat tgtaattgcc ggatctgttt gaccaatttg cacactgaat ataccaaatt
      241 catcccgaat attatcaatt acttccaaag gggacttttt atttgcttcg attaaagtaa
      301 tacctgacat aatcaaagca ggaactaaga ccaaaaatcc gattagcctc ttcttcatta
      361 accattacac gctccttcat ggaaaagaat ccctccttta ttaatactac gcaaatcatc
      421 attgaccttt atattttatt accaacattt acatcgaact tttgttctgg tttatcttga
      481 atgaagaacg tttgttctgt taatattaga tcaataaagg agtggggcga tatgcttaga
      541 gatcgaggaa caatcaaatg gacatcaatg atgcttccag acatttgaca cagcttaaac
      601 aagatttgat tgatgtatca aaaatttgaa aagccatcct tagatgatca acaaattgaa
      661 gagatggata ttctcgtctc tgaggcactt gaatttaaca aagagttgca atttaaactt
      721 tttcacaatg gattcgttga aaatgtcacc ggcagagtcc attacataaa ttttgaacaa
      781 caaaagcttc acgtaaaaga ccagaatgac aatacagttt atatcaacat gaataacatc
      841 ataggagtta catacaatga ttgattactc acaatttcca cgtaagaata tactttgtgt
      901 cgatatgaaa tccttttatg cttctgtatc ggctgtaaca atggggctta accctttaac
      961 atgctatctt gctgttgtag ggaatacgga gagacaggga agtgtagtat tagctgcatc
     1021 tcctgcactt aaaaaagatt ttggaatcaa aacaggatcg agactatttg agatacctga
     1081 agatccaagg atacacattg taaatccaca aatgaagctt ttcatcagag tttcaactga
     1141 aattacaaag ctgttttaca gatttgttcc tgagaaatgt gtccatacgt attcaattga
     1201 tgaatctttt ttagatgcag gaaaagaaga tcctgaagaa atggccaaag caatccaaag
     1261 cagcatgtgg agagaatttg gtttgatgtg cacagttggt attggagaca atatgctact
     1321 cagtaagctt gcacttgacc tggagagtaa gaaaacaaag agtggcattg cacgttggag
     1381 atatgaagat gtaccaaata aactctggaa ggttcgccct ttgtctaaaa tgtgggggat
     1441 aggagggagg atggaaagaa acctaaatcg gatgggaata tcgactatag gtcagttagc
     1501 caaatttcct ttagagctgc ttgaaaagaa gttcggaata atgggaaacc agttgtacta
     1561 ccatgctcac ggaattgatt tatcagaaat aggtgctccg ttgatgcaag gtcagattag
     1621 tttcggtaag agtcagattt tactgaggga ttacacaagg agtgaagaga ttaaggcggt
     1681 tcttctggag atttgtgaag aagtcgcaag aaggcacgta cacataataa agttggtcga
     1741 acaatcagtc tgggaattgg gtacagtaag gatgagcttg gtggtggttt tcatcgttcc
     1801 aaaacaattg atcttcctac aagtatcacg atggatattt atagatgctg cttgatgctt
     1861 tttaataagt tttactcggg taagactgtg agaagtgtct cagtcacgtt atcgaatatt
     1921 gaggatgatg ttaatcagca gctgagttta tttgaagtgg ataatgaaaa gagaaggaaa
     1981 ctcggttttg taatggatgg gattagaagt aaatacggct ctaaagcgat tctgagagca
     2041 gtttcttata caccagcagg aactgcactt caacgagctg gattaacagg tgggcataag
     2101 agttaagata aatttaaact tatataacac atcgcttaaa gtttttttgt tttaaaaact
     2161 taaaaaacat ggtaaaatta tataaaaaca taagaaagag tgattatatg gaatatgtag
     2221 ttatgataat cattttatta gcacttttct ttatttttac tgttttccta aatacacgtt
     2281 atagttttga tgaaaaatgc ttagtcttaa aatttggttt atctaaaaca gaaattccaa
     2341 ttaatcaaat agttagtatt aaagagtcag acaagtatgg agttgcagat aatatcgatt
     2401 ataaaattgg tatgccatat gctcaaccag atagaattgt tattgaaact acaaataagc
     2461 gttttctagt ttttttaaat ggagctcaac aatttattca aaagtataaa agggttagtg
     2521 tttgaacata aaaaagtacc ttcttacaat agaaggtact tttttgtatc tataattatt
     2581 aaaaatttac ctaaattttt atcattatta attcaaaata aatccataat agtcaatttt
     2641 atttagtgta ttacaaccaa ttctgtttat tgataggtaa taaagttttt tttctatgat
     2701 ttatgaacaa gtttccttat aattttcaaa aaaaaataaa aaatatggtt gaatttagat
     2761 ttatcttcct ttatattaaa aaatgtaatc cggattgcaa acaaatgggg aggttttaca
     2821 aatggaaaag ctatttaaag aagttaaact agaggaactc gaaaaccaaa aaggtagtgg
     2881 attaggaaaa gctcagtgtg ctgcgttgtg gctacaatgt gctagtggcg gtacaattgg
     2941 ttgtggtggc ggagctgttg cttgtcaaaa ctatcgtcaa ttctgcagat aaaacatttg
     3001 tagagggaat attttaaata ttccctcata tttaaagcgg ggattgaaat tgaataagaa
     3061 aaagaaatat gttcatacta aacagtttaa tagtcatgat tgtggactag cttgtatctc
     3121 gtcaatttta aagtttcata accttaacta tggaattgat ttcttactag acctaattgg
     3181 ggataaggaa ggctatagtt taagagactt aattgttatt tttaagaaga tggggataaa
     3241 aactaggcca cttgaattgc aagaaaataa gacattcgaa gccctaaaac aaataaagct
     3301 cccttgtata gctttgttag aaggggagga atatggacat tacataacaa tatacgaaat
     3361 tagaaataac tatttacttg ttagtgatcc tgataaagac aaaataacta aaataaaaaa
     3421 agaggatttt gaaagtaaat tcacaaactt tatattagaa attgacaaag agtcaattcc
     3481 tgaaaaagaa aaagatcaaa aaaaacattc ttactttttt aaggacatac tttttagaaa
     3541 taaattgatc gtttttgtga ttttattgac ttccttgttc gttgtgggtc ttgctgtagc
     3601 tgggtcgttt tatataaagt ttctagttga cctaattatc ccaagaagct taagagaatc
     3661 tttaatcaca atcactttaa tattcataag tatggtctta ataaggtgca tcttcgattt
     3721 tgtaagatca tatttgataa taaaattgtc ttacaaagtt gataaagaga tgtcaaatgt
     3781 ttattttaat aaagtaacaa aattacctat taattttttt gaaaacagag aagatggaga
     3841 ggtaatttct cgattcaatg atggtatata tattaaagac ttttttagtg ctaactttgt
     3901 tactgcaata attgatataa ttttaatact gggattagga gttattttat atagaacaaa
     3961 taacattctt ttcttaacaa ttattctccc gattttgcta ctttcatgtc tagcgatttt
     4021 gttttttgat catcttaaaa agaaaaatca aaaactgatg gaggataagg ctaaatctac
     4081 ctctctttta attaattttc tgaagaatat gacaactgtt tattctttaa ataaaacctc
     4141 gtttttttta gaaaaatttc atcttacata tgataaacaa ttaaattcaa cctttagtgt
     4201 agcaaaggca gttattagca atgaaatact aaaaggatta attcaaaact cttttacaat
     4261 aattatccta tgggttggga caagacaagt tctaaatgat tcaatgagtt tgggtacact
     4321 gctatttata aacacattag cagccttttt gctaagttca ctagatcgta tattgagtat
     4381 gcaatcagat cttcagcagg cacatgttgc ttccataaga ttttttgacg tagtaaacta
     4441 tccagttcag caagatagca atgagaattt aactgaactt gattttattc agaatatcaa
     4501 aacagttaat cttaatattg gggcagaccc aatgcgttat atagttgaag atattaattt
     4561 aatattagac agaaaggata aagtccttat tattggagaa agtggtactg gaaaaagtac
     4621 gtttgcaaaa agtttgtcta aattgtataa agtacccgat aagtcaattt atttaaatgg
     4681 attagatatt aatcgatacg atcatttatc aataagaaaa aggattgtat atattgacga
     4741 aaatcctttt ctttttaagg gaaccattaa agagaatctt tgcatgggag agatttttga
     4801 tcagaacgaa attgaaaacg cgtgtataat gtcccaatgc catgaattca tttgtaactt
     4861 ggacaagcag tacagttata aattgtctga aaacggttcc aatctatcta caggacaaaa
     4921 acaacggtta gcattagcaa gagcaatttt acatcaacca caagtattaa ttttagatga
     4981 gtcattatct aacattgatc cggataacac aaaattgatt tatgaaacct tacacaggat
     5041 ggattgttta attattctta taactcataa tgacccaagt aacttcaaat acaataaaaa
     5101 attagtattc agaaacaata ggattataga gtcgagctac tcggaaaata aggagtattc
     5161 tatatgaaaa agtggattgt tttatttctt gttttaatag cag
//
