BGC0000559: subtilin biosynthetic gene cluster from Bacillus subtilis subsp. spizizenii ATCC 6633
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Location: 1 - 14,616 nt. (total: 14,616 nt).
This entry is originally from NCBI GenBank U09819.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000559
Short description subtilin biosynthetic gene cluster from Bacillus subtilis subsp. spizizenii ATCC 6633
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
U09819.1
via Knock-out studies, Enzymatic assays, Heterologous expression, Gene expression correlated with compound production
Compounds
  • subtilin
Species Bacillus subtilis subsp. spizizenii ATCC 6633 [taxonomy]
References
Chemical products information
subtilin Evidence:
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C148H227N39O38S5
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAB91586.1
  • spaB
 495 - 3587 (+) SpaB
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    • AAB91587.1
    • spaT
    		 3578 - 5422 (+) SpaT
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      • AAB91588.1
      • spaC
      		 5395 - 6720 (+) SpaC
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        • AAB91589.1
        • spaS
        		 6795 - 6965 (+) SpaS
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          • AAB91598.1
          • spai
          		 7548 - 8045 (+) SpaI
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            • AAB91597.1
            • spaF
            		 8032 - 8775 (+) SpaF
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              • AAB91596.1
              • spaE
              		 8772 - 9527 (+) SpaE
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                • AAB91595.1
                • spaG
                		 9688 - 10299 (+) SpaG
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                  • AAB91594.1
                  • spaR
                  		 10317 - 10979 (+) SpaR
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                    • AAB91593.1
                    • spaK
                    		 10970 - 12349 (+) SpaK
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                      • AAB91592.1
                      		 12559 - 12885 (-) Orf1
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                        • AAB91591.1
                        		 12976 - 13395 (-) Orf2
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                          • AAB91590.1
                          • yvan
                          		 13424 - 13831 (-) Yvan
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                            Biosynthesis information
                            Annotation changelog

                            Entry version: 3

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2022-10-07
                            Update chemical activity to schema version 2.11
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 2

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2019-10-16
                            Migrated from v1.4
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 1

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2015-06-12
                            Submitted
                            • (ID: E5I4QXFMI3VSYYO3K7I7IJJH)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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