LOCUS       BGC0000561             16519 bp    DNA     linear   BCT 07-JUL-2010
DEFINITION  Streptococcus thermophilus tepA gene for thermophilin 1277 and
            hypothetical bacteriocin-related proteins, complete cds, strain: SBT
            1277.
ACCESSION   BGC0000561
VERSION     BGC0000561
KEYWORDS    .
SOURCE      Streptococcus thermophilus
  ORGANISM  Streptococcus thermophilus
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 19:52:26
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16519
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1050
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10682.1"
                     /transl_table=11
                     /translation="MLMASTEKGGTGLNVQSRMKAVHHLDVPWRPSDIVQRNGRLIRQG
                     NMHQEVDIYHYITKGSFDNYLWQTQENKLKYITQIMTSKDPVRSAEDIDEQTMTASDFK
                     ALATGNPYLKLKMELENELTVLDNQKRAFHRTKDEYRHTISYCEQNLPVLEKRLSQYDR
                     DIAQSLATKSQDFIMRFDNQMMDNRAEAGDYLRKLITYNRSETKEVRTLATFRGFELKM
                     ATRSLSEPLPDMVSLTISGSNQYSVSLDLKSDVGTIQRITNAIDHILEDQEKTEEMVNN
                     LKDKLSVARVEVEKVFPKEEDYQLVKAKYDILAPLVEQEAEIEEIDASLAKFNEMSQPQ
                     QNQQLSLDF"
     source          1..16519
                     /db_xref="taxon:1308"
                     /mol_type="genomic DNA"
                     /organism="Streptococcus thermophilus"
                     /strain="SBT 1277"
     subregion       1..16519
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000561"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..16519
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..14631
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2117:4631]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2118..4631
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..14631
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     CDS             1120..1419
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10683.1"
                     /transl_table=11
                     /translation="MTQTVEELRYQLEEWLAQGFTSPEDRANYQTLKEQYEDETLDYSF
                     SKREIIGQLEVIITTRENDFPDLDEVTKGEYLDLVEQLDNLDKGQADYYRKQLA"
     CDS             1432..1722
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10684.1"
                     /transl_table=11
                     /translation="MIEQIIQSLFIIAATGLILLVLYQIAKMLGSLFVIGSIGFLAFTE
                     VYGIYLFFTERYLYVEDLATNGIWSFTVFYIAFNLLIVAGLVIKVVRNRIV"
     gene            1861..2037
                     /gene="tepA"
     CDS             1861..2037
                     /codon_start=1
                     /gene="tepA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) leader_eh"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /product="thermophilin 1277"
                     /protein_id="BAJ10685.1"
                     /sec_met_domain="L_biotic_A (E-value: 1.3e-20, bitscore:
                     63.5, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="leader_eh (E-value: 2e-07, bitscore: 21.8,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNATENQIFVETVSDQELEMLIGGADRGWIKTLTKDCPNVISSI
                     CAGTIITACKNCA"
     CDS_motif       1861..1935
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MMNATENQIFVETVSDQELEMLIGG"
                     /locus_tag="tepA_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       1936..2037
                     /prepeptide="core"
                     /locus_tag="tepA_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.20"
                     /molecular_weight="3359.9"
                     /monoisotopic_mass="3357.7"
                     /core_sequence="ADRGWIKTLTKDCPNVISSICAGTIITACKNCA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MMNATENQIFVETVSDQELEMLIGG"
                     /leader_location="[1860:1935](+)"
                     /alternative_weights="3378.0"
                     /alternative_weights="3396.0"
     gene            2118..4631
                     /gene="tepM"
     CDS             2118..4631
                     /codon_start=1
                     /gene="tepM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     459; E-value: 5.6e-139)"
                     /gene_kind="biosynthetic"
                     /product="hypothetical bacteriocin modified enzyme"
                     /protein_id="BAJ10686.1"
                     /sec_met_domain="LANC_like (E-value: 3.8e-29, bitscore:
                     91.9, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="DUF4135 (E-value: 4.1e-58, bitscore:
                     187.7, seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLDLTINNESESFHKIIDNIVSDFYLVILDAVQTNAELSNVHK
                     YLYKNIRQVLLPILVQDINEWRLESKHQKNDTNQEYIDYCYQFISKNRFAYLKNKYELL
                     NLRIDTIISETKLNLKNFLKNIDKSVSSLKKVFPQCDFEIKKLKFIDFIGDNHGLYQSI
                     MFEVSGKVFFYKCHGSEITNFIVTLQKEIPSLNFLKLPMTYIDQEFIIQEKVTHSSVLI
                     KDDIEEYYHNMGKLLGILYLLNGNDMHNENIIARGKNPIVIDVETLINPIECDSDSKMD
                     DSIFSVGMLPMKYNRNFEGIFDTSSLGQSNIVSEKVFKEYKPFTSEIQLVLIDHTFSDL
                     DRYLPRYKEIHFDVIDYLGVVEDGFIESYHLIMNHKKEIAKVISREASNINCRIVLRNT
                     RIYSEILKFLSTPSLLKNITKAEDTLKRLLVKPRYIIHNWERYRQQEIKQLLNGEIPYF
                     SFGKYGNTSPNDLNLSSVETSLQCKLNRFSDDDLKFQLILLRTSLNIDDDNFEVIGKEN
                     FRGKLKDLIKSSIYGTDIFTLQKDWCGNYIYGESNLGLYEGKLGIILSDNYFSDIFDVS
                     SIRREILFSRDISFIDGRASLDVFDIINNDSILSPVSVEISNKYLDLIEGISGVILARY
                     KFYCQKLPENISELEQLMRQFMRLYKNSSELKNGFAHGISGIKIIFYIAYQILGEEKYL
                     DEFKKLEILDFPEKYTNGSWCNGLLGWITSEYILYTISGDKTFKENILNHLPRLMTYLI
                     DLSDYCLCHGSFGVLDFLLTLSQKELLPKEFHDEYVKLEKYHLEMITQCRILKKDVSLF
                     TGISGILYYLNRKESGKNSVLTFGF"
     gene            4645..6687
                     /gene="tepT"
     CDS             4645..6687
                     /codon_start=1
                     /gene="tepT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 149.3; E-value:
                     2.6e-45)"
                     /gene_kind="transport"
                     /product="hypothetical bacteriocin transporter"
                     /protein_id="BAJ10687.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.3e-34, bitscore:
                     108.0, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKIKEEIQFQQNDCGPCCLSMILNYYDYQITVPELSSQLSKKNG
                     WSMLDLKTVAAKYYLQSNVFKITDLKGFDKLQCPLVLFWESSHFVVLESISENIVIVDP
                     SIGHVKLNRNEFNQKFSGFAMSFVKNEHFQKRKLSKLRYVKEFNKAEVWSLNFSKKYLL
                     LLLIYNMLLFLAPVVISLFISDLQKSKAYNLIWLALLLFVVAIVVFLLEREKASAVLKL
                     ERDSTYKIYQKIMFQKDSTLSKYHSGDILTRIFSNSEICRFISIDLPNIVSSVILFTTV
                     SVYLVYRIGHLSIFLIFFVLSIGILNGIFVKPLIGLSKKEGYKLSDFRSVSNDGITSHG
                     YLFNSGAIKNYLNKFLNSLSSYIQFSDEKNKFEALATTAQQASNLFFSMLISLLGLSLV
                     ILFPKSSGNVSLLMSSGMILVTPVMSVVSSIVNFAVSYPSFIRLVELINSLEHVSDEQI
                     MENGEIEISNLSFKYPEMKYNIFHNFTVKISQGEQVIITGASGTGKTTLINLILGLEEE
                     YEGEVIVGGVNTKLSNLDLRKDVCYISQPSKLFKGTLKENLELYLDSYHYDELVKLSDK
                     IGLSELMNDISNFENILLLEDGRNFSLGQRQRLTLLRAFLGKYKLVIFDEPTSNLDFSH
                     AKQIFSLIEKIDATKIIITHDKQFLDSSQTIIDLGGQNGYKIMQN"
     gene            6662..7570
                     /gene="tepF"
     CDS             6662..7570
                     /codon_start=1
                     /gene="tepF"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 176.4; E-value:
                     1.2e-53)"
                     /gene_kind="transport"
                     /product="hypothetical bacteriocin immunity protein"
                     /protein_id="BAJ10688.1"
                     /transl_table=11
                     /translation="MDIKLCKINKNYGSRKILKGLNVNVPSGEIYGFIGANGSGKTTTM
                     KIMTGLTPANHGVVEFDGLTLKELAKSEKSFGAFISTPTYYKNLTAVENLTIVQDILGK
                     PKSEVYRVLELVGLSEAADKEVRSFSFGMKQRLGLAFAFLNNPDILILDEPTNGLDPKG
                     IVEIRELLRRLSQEEGKTIFISSHNISEIEAIADRVGIIHQGSLVFEGTLDELYRSNHS
                     TYILEVNDEEKTRQLLTEKRIDFMNHQTRFEINLSKSNIPSLLTELIEREISVYEMTPN
                     KNLERIFLNLTAGGTENAISY"
     CDS             7554..8276
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10689.1"
                     /transl_table=11
                     /translation="MLSLIKSEFKKNGNGTQIYLSLAVLLAIQIILMMIIINSFNLTGF
                     GDLKTTEFRKSLLSFAGFSYLFTIFVGAIVGYYFISKEYLNNTWELLILGIKNKFQVVL
                     SKFIVGIIIYIFYQILSLTCFTFLVKTYFGDTIEWSFFMLILVANLSCNLLFYVIQLSA
                     HFLISNSMTAITFSLLLVILPIFLGNNFLFVNFIPLISISYIVNSMAFSMVHFILLSMW
                     TVLVSGFTVIGVSKYFRL"
     CDS             8283..8999
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10690.1"
                     /transl_table=11
                     /translation="MKMKFWRFELYKYRRSMGLAIILFLTTIIVLLQSYTGYITKEIPS
                     KALYATGLDLLSMLIFPVLIPMVISLSHYIDKENLGLQNLFLKGIDIKQFKLFRWLFYV
                     VGFPILFLIYFGIVLVFIGLRGENIFLTFYNLIPYLLLVVLSIMTLVNISFCIYDLAKQ
                     NSLLPILIGLGGAILGTFPFGDHIWLMNPYSYLNYVFSFRRLHTYHIVILIVVTIVTFG
                     GIMILNTSRTECEYEG"
     gene            8989..10500
                     /gene="tepK"
     CDS             8989..10500
                     /codon_start=1
                     /gene="tepK"
                     /product="hypothetical bacteriocin immunity protein"
                     /protein_id="BAJ10691.1"
                     /transl_table=11
                     /translation="MKVNSLKISIMYQLVLVIMIIGLGYHHTFNDESSILPLLLEFLFL
                     FIEFILVKIITIKTKFLATCLWTLRLAQIQTISLIIYRGVPLLLQYIIAVLLFNLMLLL
                     VFKLLLQDEKITPVKWTILFGIISSIVSVSFPSFVAPFFVCYMFIVIGILLFYGHKKWN
                     SSVYSHSKNWSYWICMFVFVFNILFLSSVMLFVPGLDLFSGIWQVIVAEFILVLFGILF
                     YNNRLLLSNSNLLLTICLLFLLYWIIFAYIIKRPLQEVLWMELISFALAYIGSLIHHLH
                     LLNGESDNHYNGLSALISEERLKEEFANFLHDDILQDLNAMIQLSRIKNSNEVLPIIND
                     NLERLNVFTRNQMNIYSPQLLKGLSLYENYLQMIESIKKRYPNLPLKIKLSMDSDLKLP
                     PPYDVLVYRWLRELVNNCYKYAQANSLKIDLVIEGAICKISVSDDGIYTSQTTLGEGHG
                     IKTIYSQLRAVGGSLKQYQVMPHGYGILIVFEIEGDRAIESFINR"
     gene            10721..11074
                     /gene="tepR"
     CDS             10721..11074
                     /codon_start=1
                     /gene="tepR"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1197:autoinducer-binding transcriptional regulator,
                     (Score: 62.5; E-value: 6.1e-19)"
                     /gene_kind="regulatory"
                     /product="hypothetical bacteriocin immunity protein"
                     /protein_id="BAJ10692.1"
                     /transl_table=11
                     /translation="MLTGFDLPVYEYKAEQLGIEGFVNKNIEAETLLEVIDSVISGHNY
                     YSKEVEFHDELTDREKEILVFLGEGNKRKEIASKLFISDRTLTNHIQNILEKLEVDSTI
                     RAIIKARKMGYIK"
     CDS             11143..11301
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10693.1"
                     /transl_table=11
                     /translation="MKKYIPLICFLLFIVFLGITVRAFLADKTLMVADGLLSIVFFISF
                     LITRKKL"
     CDS             11313..11798
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10694.1"
                     /transl_table=11
                     /translation="MKKIFKVHLFSLICLVALAIGGNNVYADVNSVNQPSVESATSIEN
                     YNSNIEGLRKIDFATLKSIFDSTSEQSFTIYFGRPTCYYCRLFSPTLKEFNQLLNGGLI
                     YYDTSGQDFDSTAQQFVFDELGIPGTPTIIYVKHGQILNGWVGGGTTAQELMNYLYK"
     CDS             12012..12662
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10695.1"
                     /transl_table=11
                     /translation="MALSMLNKMKARLLIGFGGLAVISFIVMMGYTIGSQSVTNHTQKQ
                     IQSEAQKLLTKEKEKEKASVLSDELVKEFLTQYYTKEKLGENNNRIKPYMTDSAFKEEV
                     ARQEDSINQVYKDYMLDYRFESANIYVNTEANEAFAEVSYQVVYVSDVSDKAQKSTQTE
                     TTSLKLSYAKLSDKLLVNQVTIWKGKLEDLKESSDEVSSSIPKIQGTTTSETN"
     CDS             12702..13790
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10696.1"
                     /transl_table=11
                     /translation="MTRIEAVKQKAILEVAESLGYSFKHLSGQVYEHPEHDSFRIFADT
                     NTFKWFSRDVQGDVIDFVQLMTGVSFKKALSYLETGDFEQAKIVEETYQPFRYYLREEP
                     FDQARIYLNDIRGLSDETINAFGRQGLLAQAHYQTNTFQESVLVFKSYNHHGQLEGASL
                     QGLVKDNQRHDRGYLKKIMKDSHGYIGMSFDIGKPKRLIFCESVIDMMSYYQLHQKQLS
                     DVRLVSMEGLKLSVIAYQTLRLAAEEQGKLEFLDTVKPSRLTHYLHAMQETTTFFQMHT
                     GLLTLAVDNDEAGRDFCQKLSEKGLTIETDCPPLQELETKADWNDIVKYQNNYSLKDVI
                     QSAKLQVIRSNPPPRKNTALEL"
     CDS             13844..14071
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10697.1"
                     /transl_table=11
                     /translation="MSVIERLAERVARQEEKVAKETEKLETYRSQLQTAMYQAFIKRQQ
                     SSPWTFDEALTQAFGQDEQELKLSDTRNEE"
     CDS             14075..14470
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10698.1"
                     /transl_table=11
                     /translation="MTKDWTFDQPLDDNTPTSSTEERAKIAALFHKENQEGTEDVDYVA
                     AFEMEQQKAKEKSVSQPKTQEQSTPKEVSSSNITNDYKQHLADVMAQNNEDILQSQKKI
                     EELHQLIDDKNKQNKKLQAISAAIDDL"
     CDS             complement(14831..15130)
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10699.1"
                     /transl_table=11
                     /translation="MNQLDFYKNELQMDYFSDNYRKFESDFYRYSALDTPLTFLTDDIM
                     LAMAKSAKNYFKLNKENAKDNRDHYFIFDIENLNDSKLTKKYVYQRTTSIRQKD"
     CDS             complement(15117..15485)
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10700.1"
                     /transl_table=11
                     /translation="MIDRSYLPFQSARDYQDVNMQKWMGFFLSEHTSALSDDDKQVSYL
                     SDLLLNQKLMLLSQSYANQLTIQVTRRQENDYQTIIGTIPTLSTNEVILKTNDGHIAIA
                     LEDILAITLVEEVYHESA"
     CDS             complement(15482..16402)
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="BAJ10701.1"
                     /transl_table=11
                     /translation="MDRKAKLDVVSAKLQHDIWKKTGIYSTIGMSNANPLLAKLALDNE
                     AKRTPTMRANWSYEDVETKVWSIPHLTDFWGIGSRTEKRLHKLGITSIKELANSNPDRL
                     KKEFGKVGLQLWFHANGVDESNVHQPYKPKSHGLGNSQVLPRDYVKQRDIEIVLSEMAE
                     QVAIRMRREHQKATIVSIFVTYSKTEMKQPINAQMKIEPTNHTRLLTDTVLTLFRKKYT
                     SGAVRGIAVNYSGFVDESYALISLFDDIEATEKEEKLQQTIDHIRDQFGFLAVQKGTAL
                     LDSSRNIARSKLIGGHSAGGLEGLQ"
ORIGIN
        1 attcttatgg cttcaacgga aaaaggtgga acaggtttaa acgtgcaatc acgcatgaaa
       61 gccgtccacc acttagatgt tccctggcgt ccctctgata ttgtgcagcg aaacggtagg
      121 ttaattcgtc aaggcaatat gcaccaagag gtagatattt accattacat tacgaaaggg
      181 agcttcgaca actacctctg gcaaactcag gagaataaac tcaaatatat cacgcaaatc
      241 atgacctcta aagatcctgt acggtcggca gaagacattg atgaacaaac catgactgct
      301 tcagacttta aggctttagc gacaggtaat ccttatctca aactgaaaat ggaactagag
      361 aatgagttga cggtcttgga caatcaaaag cgtgcctttc atcgcactaa agatgagtat
      421 cgccatacca tttcttactg tgagcagaac ctccctgtat tagagaaacg cctcagtcaa
      481 tatgaccgtg atattgccca atctttggca actaagtcac aagattttat catgcggttt
      541 gacaatcaaa tgatggataa ccgtgcagaa gctggagact atttacgaaa actcattacc
      601 tataaccgtt ctgaaaccaa agaagtcaga acgcttgcga cctttagagg gtttgagctt
      661 aaaatggcaa ccagaagtct tagtgagccc ttgccagata tggtgtcttt aaccatttca
      721 ggtagcaacc agtattctgt ctctttagac ctgaaatcag acgtgggaac cattcaacgc
      781 attaccaatg ccattgacca tattttagaa gaccaagaaa agacagaaga aatggttaac
      841 aatttgaaag ataagctatc agtcgcaagg gttgaagtag agaaggtttt tccaaaagaa
      901 gaagattatc agctggttaa agccaaatat gacatccttg cccccttggt tgaacaagaa
      961 gcagagattg aggaaatcga tgcatcacta gctaaattca atgaaatgag ccaaccgcaa
     1021 cagaaccaac aactttcgct tgatttttaa gaaaaaggct gacaaaaaat aatgaacgcg
     1081 gtaaaatgac attaagaaat catcaaagga gaattgatta tgacccagac agtagaagaa
     1141 ttaagatacc aactagaaga atggctagca caaggtttta caagccctga agatagagct
     1201 aactatcaaa ccttaaagga acaatatgaa gatgaaaccc ttgattacag cttttcaaag
     1261 cgagaaatca ttggtcaatt agaagttatc atcacgactc gagagaatga ctttccagac
     1321 ttagatgaag tgactaaagg agagtatcta gacctggttg aacaacttga taatctagac
     1381 aagggacagg cagattatta tcgtaagcaa ttagcgtaga aagaggcaga tatgattgaa
     1441 caaattattc aaagtctttt cattatcgca gcaacagggc tgattttgct tgtcctttac
     1501 cagattgcga agatgcttgg aagcttattt gtcattggtt caatcggatt tttagctttc
     1561 acagaagtct atggaattta cctctttttt acagaacgat acctctatgt ggaagattta
     1621 gccaccaatg gtatttggag ttttactgtt ttttatatcg cctttaatct tctgattgta
     1681 gcaggtcttg tgataaaagt cgtgagaaat agaatagtat aaaaataaaa agggctgcct
     1741 gagtgaagtg ccctttttaa aatttgcctt ttttactcat tacaagctct atgcttatat
     1801 tatatactac gtaatgtaaa ggatgtagct atgatattat aaaaatagga ggaaactata
     1861 atgatgaatg ctactgaaaa ccaaattttt gttgagactg tgagtgacca agaattagaa
     1921 atgttaattg gtggtgcaga tcgtggatgg attaagactt taacaaaaga ttgtccaaat
     1981 gtaatttctt caatttgtgc aggtacaatt attacagcct gtaaaaattg tgcttaattt
     2041 attgccgtca aactttttaa aatagctaca agagacctgt tagatatcta ataggtctgt
     2101 cctttttagg agagagtatg gaaaaattag atttaacaat aaacaatgaa tcagaatcat
     2161 ttcataagat aattgataat atagtaagtg atttttattt agtaatttta gatgcagtac
     2221 aaacaaatgc agaactatca aatgtccata aatatttata taaaaatatt agacaggttt
     2281 tgttaccgat tttagtgcaa gatatcaatg aatggagatt ggaaagtaaa catcagaaaa
     2341 atgatacaaa tcaggaatat attgattact gttaccaatt tatatcgaaa aatcgatttg
     2401 cttatttaaa aaataaatac gaacttttga atctaagaat tgatactatt atctctgaaa
     2461 ccaagctaaa tttaaaaaat tttttaaaaa atattgataa gagtgtgagt tctttaaaaa
     2521 aagtatttcc acaatgtgat tttgaaatca aaaaattgaa gtttattgat tttatcggtg
     2581 ataatcatgg tttatatcag agtataatgt ttgaagtatc tggaaaggta tttttttata
     2641 agtgtcatgg ttctgaaatc acaaatttta tagtcacatt acagaaagaa attccaagct
     2701 taaatttcct taaactacca atgacatata tagaccagga gtttattatt caagaaaaag
     2761 ttacacattc ttctgttttg ataaaagatg acatagaaga atattaccac aatatgggta
     2821 aattattggg aattctatat ttgctaaatg gaaatgatat gcacaatgaa aatatcatag
     2881 caagaggtaa aaatccaatt gtgattgatg tagaaacact tataaatcca atagaatgtg
     2941 atagtgactc aaaaatggat gatagtatat tttcagtggg tatgctccct atgaaatata
     3001 acagaaattt tgaagggatt tttgatacaa gttcattagg gcaaagtaat attgtttctg
     3061 aaaaagtgtt taaagaatat aaaccattca cttctgaaat ccaattagta ttaatagatc
     3121 atacattttc tgatttggat aggtatttac caaggtacaa agaaatccat tttgatgtga
     3181 tagattattt aggtgttgtt gaagatggtt ttatagaatc ttatcatctt attatgaatc
     3241 ataaaaaaga aatagcaaaa gtaattagtc gggaagcctc caatataaat tgccgaatcg
     3301 ttttaagaaa tactaggatt tatagtgaga ttctcaaatt cttatcgact cctagtcttc
     3361 taaaaaatat tacaaaagca gaagatacct taaaacggtt attagtaaaa ccaagataca
     3421 tcattcataa ttgggaaaga tatagacagc aagaaattaa acagttactt aatggggaaa
     3481 taccttattt ttcatttggt aaatatggaa acacatcacc aaatgatcta aatctatcaa
     3541 gtgtagagac ttctttacaa tgtaaattga accgattttc tgatgatgat ttaaaatttc
     3601 agctaatctt gttaagaact tcattgaata ttgatgatga caattttgaa gttattggaa
     3661 aggaaaattt tagagggaaa cttaaagacc ttataaaatc atctatctac ggaaccgata
     3721 tttttacatt gcaaaaggat tggtgtggaa attatattta tggggaaagt aatcttgggc
     3781 tttatgaagg aaaacttggc attatcttgt cagataacta cttctctgat atttttgatg
     3841 taagtagcat tcggagagaa attttatttt cacgagacat tagctttata gatggtcgtg
     3901 ctagtttaga tgtgtttgat ataataaaca atgattcaat tctttctcca gtatctgttg
     3961 aaatatcaaa taaatatttg gatttaattg aaggtatatc cggagtgatt cttgctaggt
     4021 acaagttcta ttgtcaaaaa cttccagaaa atatttcgga attagaacaa ttgatgagac
     4081 aatttatgag attgtacaaa aatagcagtg aattaaagaa tggatttgca cacggtattt
     4141 caggtattaa aataattttt tatattgcgt atcagatatt gggggaagaa aaatatttag
     4201 atgagtttaa aaagcttgag attcttgatt ttccagagaa atatactaat ggatcttggt
     4261 gtaacgggtt actaggctgg attacgtctg agtacattct atatacgata agtggggata
     4321 aaacttttaa agaaaatata ttaaatcatc taccaagatt aatgacttat ctgatagatt
     4381 tgtctgatta ttgtttatgt catgggagct ttggagtatt agatttcttg ttaacattaa
     4441 gccaaaaaga gttattgcct aaggaatttc acgatgaata tgtcaaactt gaaaaatatc
     4501 acttggaaat gattacacag tgtagaatct taaaaaaaga tgtttcactg tttactggca
     4561 tttcaggtat actatattac ttaaatagaa aagaatcggg taagaactca gtactgacgt
     4621 ttggatttta gaggtataat aagaatgagg aaaattaaag aagaaattca atttcagcaa
     4681 aatgactgtg ggccttgttg cttatctatg attttgaatt actatgacta ccaaataact
     4741 gtacctgaac tttcatctca attaagtaaa aaaaatggtt ggagtatgct tgatttaaaa
     4801 acggttgctg ctaaatatta tcttcaaagc aatgtcttta aaattactga cttaaaaggg
     4861 tttgataagc tacagtgtcc tttggtttta ttttgggaaa gctctcattt tgtcgtatta
     4921 gaaagcatct ctgaaaatat tgttatagtt gatcctagta taggacatgt aaaattaaat
     4981 cgtaatgagt ttaaccaaaa attttctggt tttgcaatgt catttgttaa aaatgaacac
     5041 tttcaaaaaa ggaaattaag taaattgagg tacgttaaag aatttaataa agcagaagta
     5101 tggagcttga atttttcgaa aaaatactta ctcttattgt taatttataa tatgctttta
     5161 tttttagctc ctgttgtaat tagtctattt atatctgatc ttcagaaatc aaaagcctac
     5221 aatttaattt ggttagcctt acttttattt gttgtagcta tagtagtttt tcttttagaa
     5281 agggaaaaag cttccgcagt acttaaatta gaaagggatt caacttataa aatttatcag
     5341 aaaattatgt tccaaaagga ttcgacactg tcaaaatatc atagtggcga tattctaaca
     5401 agaatttttt cgaattcaga aatatgtaga tttatttcga ttgatctacc aaatatagtt
     5461 tcatctgtaa tattatttac aacagttagt gtgtacttgg tttatagaat tggtcatctc
     5521 tctatatttt tgatattttt tgtattaagt ataggaatat tgaatggtat atttgttaag
     5581 cctttgattg gcttatctaa gaaggaagga tataaactgt cagattttag atctgtatcg
     5641 aatgatggaa ttacatcgca tggatattta tttaattctg gagccataaa aaattatcta
     5701 aataaatttt taaattcttt atcaagttat atacaatttt cagacgaaaa aaataagttt
     5761 gaagctttag ccacaactgc tcaacaagcg tcgaatctat ttttttcaat gttaatctca
     5821 ttacttggac taagtttagt aattttattt ccaaaaagta gtggaaatgt ctctttgtta
     5881 atgtcatctg gtatgatatt agtaactcca gtcatgtctg tggtatctag tatagtaaat
     5941 tttgcagtgt cttatccaag ttttataaga ttggttgaat taataaatag tttagaacat
     6001 gtttcagatg agcagataat ggaaaatgga gaaattgaaa tatcgaattt atcttttaaa
     6061 taccctgaaa tgaaatataa catttttcat aattttacag taaagatttc tcaaggggaa
     6121 caggtgatta ttactggtgc ttcaggaact ggaaagacga ctttaattaa tcttatttta
     6181 ggacttgagg aggaatatga aggcgaggta attgtaggag gagtaaatac taaattaagt
     6241 aatttagatt tacgaaaaga tgtctgttat atttcccagc catcaaaatt atttaaagga
     6301 actttgaagg aaaatttaga gttgtatctg gattcttatc attacgatga acttgttaag
     6361 ttatcagata aaattggtct atcagaattg atgaatgata tatcaaattt tgaaaatatt
     6421 ttacttttag aagatggaag aaatttttct ttaggtcaaa ggcagagatt aacgctgctt
     6481 agagcgtttt tagggaaata taagctggtt atttttgatg aaccgactag taatttagat
     6541 ttcagtcatg cgaaacaaat attttcactt attgagaaaa ttgatgcaac aaaaattatt
     6601 attactcatg acaaacagtt tttagattcg tctcaaacta tcatagattt aggagggcaa
     6661 aatggatata aaattatgca aaattaataa aaattatgga agccgtaaga ttttaaaagg
     6721 actaaacgta aatgttcctt caggtgaaat ttatgggttt ataggtgcta atggttcagg
     6781 gaaaacaact actatgaaaa ttatgactgg attaactcca gcaaatcatg gagttgtcga
     6841 atttgacgga ttaacattaa aagaattagc taaatcggaa aaaagttttg gagcctttat
     6901 tagtacacca acctattata aaaatttaac ggcagttgaa aatctgacta tagtacaaga
     6961 tattcttgga aaacctaaaa gtgaagtata cagggttcta gaattggttg gattatctga
     7021 agctgcagat aaagaagttc gctcattttc ttttggaatg aagcaacgtt taggattggc
     7081 ttttgctttt ctaaataatc ctgatatctt gattttagac gagccgacaa acggtttaga
     7141 tcctaaaggg attgtcgaaa tccgtgaatt acttcgaaga ttatcacaag aagaaggaaa
     7201 aactatcttt atttctagtc acaatatttc tgaaatagaa gctattgctg acagggtagg
     7261 aattattcat caggggagcc ttgtctttga agggacttta gatgagttgt atagaagtaa
     7321 tcacagtacg tacattttag aggtaaatga tgaagagaaa actcgacaac tcttaacaga
     7381 aaaaagaatt gattttatga atcatcaaac aaggtttgag attaatttat ctaaaagtaa
     7441 tattccctct ttactgacgg agttgattga aagagagatt tctgtttatg aaatgacccc
     7501 aaataaaaat cttgagagaa tctttttaaa tctgactgca ggaggtactg aaaatgctat
     7561 ctcttattaa atcagaattt aaaaagaatg gaaatggcac acaaatatat ttatcacttg
     7621 cagtgctact agcgatacaa attatcttga tgatgattat tataaactcc tttaatctta
     7681 ctggatttgg agatttaaaa actacagaat ttagaaaaag tttactaagt tttgcaggat
     7741 tttcgtatct ttttactata tttgtgggag cgatagttgg gtattatttt atttctaaag
     7801 aatatctcaa taatacttgg gaattattga ttttggggat aaaaaataaa tttcaagtag
     7861 tcctatcaaa atttatagta ggtattatta tttatatttt ttatcaaatt ttatccctta
     7921 cctgttttac gtttcttgtt aaaacttact ttggtgatac tattgaatgg tcatttttta
     7981 tgttaatctt agtggccaac ctatcttgta atctgttatt ttatgtgatt caattatctg
     8041 cccatttttt gatttcaaat agtatgacgg ctataacttt ttcattgtta ttagtaattc
     8101 tgccaatttt tttaggaaat aatttcttat ttgtcaattt tattcctctc attagtatct
     8161 cctatattgt gaatagtatg gcattttcaa tggttcactt tatcttactc tctatgtgga
     8221 ctgttttagt aagtggtttt acagttattg gtgttagtaa gtattttagg ttataaggga
     8281 ggatgaaaat gaagttttgg agatttgagt tgtataaata tcggcgaagt atgggacttg
     8341 ctattattct atttctcaca acaataatag ttctactcca atcttatact ggatatatca
     8401 ctaaggaaat tccttcaaaa gctttatatg ctacaggtct agatctgtta tcaatgctga
     8461 tattcccagt gttaattcct atggtcattt ctttatccca ttatatagac aaagaaaatt
     8521 tggggcttca aaatttattt ttgaaaggaa tagatataaa acaatttaaa ctatttcgat
     8581 ggcttttcta tgtagtcggc tttccgatat tatttttaat ttattttggt atagtattgg
     8641 tgtttattgg tttgagaggc gaaaatatct ttctcacttt ttataatctg ataccttatt
     8701 tattacttgt tgttctatct atcatgacat tggtaaatat cagtttttgt atatatgact
     8761 tagcaaagca aaatagttta ctacctatac taattggtct tgggggagct atcctaggaa
     8821 cattcccatt tggggaccat atttggttaa tgaatcctta ttcttactta aattatgtct
     8881 tctcatttcg tcgtttacat acctatcata tcgtaatctt gattgtagta accatagtaa
     8941 catttggtgg tataatgata ctaaatacct caagaacgga atgtgaatat gaaggttaat
     9001 agtttaaaaa taagtataat gtatcagctt gtattagtca taatgatcat cgggctagga
     9061 tatcatcata cttttaatga cgagagttca attcttccat tattgttaga gtttctattt
     9121 ttgtttattg aatttatttt agtaaaaatt attacaataa agacaaagtt tcttgcaact
     9181 tgtctttgga cattaaggtt agcgcaaatc cagactattt ccttaataat ctacagagga
     9241 gtcccacttt tgctacagta tatcattgct gttttgttat ttaatctaat gttgctacta
     9301 gtttttaaat tattgttgca agacgaaaaa ataactcctg taaaatggac aatattattt
     9361 ggaataatat caagtattgt ttcagtttct tttccatctt ttgttgctcc tttttttgta
     9421 tgttatatgt ttattgttat tgggatactt cttttttatg gtcataaaaa gtggaacagt
     9481 tccgtttatt cacatagtaa aaactggagc tactggattt gtatgtttgt atttgtattc
     9541 aatatattgt ttcttagttc ggtaatgctg tttgtaccag gactagatct tttctctggt
     9601 atctggcaag ttattgtggc agagtttatt ctagttttat ttggaatttt attttataac
     9661 aatcgattgt tgcttagtaa tagtaatcta ttattaacaa tttgtctgct atttttactc
     9721 tattggatta tttttgcata tatcataaag agacctttac aagaggtatt gtggatggag
     9781 ttgatttcct ttgcgcttgc ttatatcggg agtttaattc accatctcca tctgttaaat
     9841 ggagaaagtg ataatcacta taatggcctt tctgccttga ttagtgaaga aagattaaaa
     9901 gaagagttcg caaattttct tcatgatgat attttacaag atttaaatgc gatgattcag
     9961 ctaagtagga taaaaaattc aaatgaggta ttaccaatta ttaatgataa cttagagaga
    10021 ctgaacgtgt ttacgagaaa ccaaatgaat atatatagtc cacaactatt gaaaggacta
    10081 agtttatatg aaaattatct tcaaatgatt gaatcaataa aaaaacgtta tccgaatctt
    10141 ccattaaaaa ttaagttgag tatggattca gatttaaaac ttcctcctcc gtatgatgtc
    10201 ttggtttatc gttggcttag agaattggtt aataattgtt ataaatacgc tcaagctaat
    10261 tcattaaaga tagatctagt aattgaagga gcaatctgta aaatttcggt ttccgatgat
    10321 ggaatatata cttcacaaac tactttgggt gagggacatg gtattaagac aatatactca
    10381 caattacgag cagttggtgg aagtttgaag cagtatcaag tgatgcccca tggatatggg
    10441 atactaattg tatttgaaat tgaaggagat agagcaattg aaagttttat taatagatga
    10501 tcatacatta ttttcacaga gtttatcatt tgctttaaaa caatttagga gtgatttgga
    10561 gatagtcgta ataaatagag aatcagattt gagaaaaatt gatgattttt cgatttatga
    10621 tgttgttttg ttagatattc acttagaaaa gtctttttct actgatgggt ttgagatagc
    10681 agagtatctg ttaaatttat cttctattat aaagattatc atgttgacag gttttgactt
    10741 gccagtttac gaatataaag cagaacaatt agggatagaa ggttttgtca ataaaaacat
    10801 agaggcagag actctcttag aggtaattga ttcagtgatt tcaggtcaca actattattc
    10861 aaaagaagtt gagtttcatg acgaattaac agatagagaa aaggaaatct tagttttttt
    10921 aggtgaaggt aataaacgta aggaaatagc tagtaagtta tttatttcag atagaacact
    10981 aacgaatcat attcaaaata ttttagagaa actagaagtt gattcaacaa tcagagctat
    11041 aataaaggct cgaaaaatgg gttatattaa ataatttcct tttttactca tgaaaaaaat
    11101 attgtattac catagaataa agatgaagga ggaattatct agatgaaaaa atatattcca
    11161 ctaatttgtt tcttgctgtt catcgtattt ttggggatta ccgtaagggc atttttagct
    11221 gataaaacat tgatggtagc ggatggactg ctttctattg tattttttat ttcattttta
    11281 atcacaagaa aaaaattgta aaggagtata ccatgaaaaa gatttttaag gttcatttgt
    11341 tttcgctaat ctgtttagta gctttagcga taggtggaaa taatgtgtat gctgatgtga
    11401 attccgtaaa tcagccaagt gttgagtcag cgacatctat cgaaaattat aattcaaata
    11461 ttgaaggttt aaggaagata gattttgcta ctttaaaaag tattttcgat agtactagtg
    11521 aacaatcttt tactatctac tttggtcgac caacatgcta ttactgtaga ttattttctc
    11581 ctacactaaa agaatttaat caattattga atggtggatt aatatactat gatacaagtg
    11641 gacaagactt tgattctact gcgcaacaat ttgtttttga cgaattgggc attccaggaa
    11701 cacctactat tatttatgtc aagcatggac aaattctaaa tggatgggta ggaggaggta
    11761 ctaccgctca ggaactaatg aattatctgt ataaataaat gatttattgg tattagaaga
    11821 acgatttaat aattttacat aatttatctt ctaataactt ttactcatat tgaagacaaa
    11881 tgctcaagaa tagagtgttt gtcttttcat tttactgtta tttgatgtaa gatgatatga
    11941 ttgcatcatt tttgtgataa tttttccaag tcaatcttgt tatgatgggg ctatcttatt
    12001 aaaaaaagga gatggcactg tctatgttaa ataaaatgaa agctaggctt ctaattggtt
    12061 tcggtggttt agctgtgatt agctttatcg tgatgatggg ttatactatt ggttctcagt
    12121 ctgtcaccaa tcacacgcag aaacaaatcc aatctgaggc tcaaaaatta ctgaccaaag
    12181 agaaagaaaa agagaaggca agtgtcctct ctgatgagtt agtcaaggaa tttctcaccc
    12241 aatactatac taaggaaaag ctgggcgaga ataacaaccg tattaaaccc tatatgacag
    12301 attctgcctt taaggaagaa gtagctcgtc aagaagattc catcaaccaa gtctataaag
    12361 actatatgtt ggattatcgc tttgagtctg ccaatatcta tgtcaataca gaagcaaatg
    12421 aagcttttgc ggaagtgtct tatcaggttg tttacgtgtc agatgtcagt gacaaggctc
    12481 agaaaagtac acaaacagaa acgacctctc ttaaactatc ttatgccaaa ttgtcagata
    12541 aactccttgt caatcaggta accatttgga aaggcaagct agaggacttg aaagagtctt
    12601 ctgatgaagt aagttcaagt attccaaaga ttcaaggcac tactacaagt gaaaccaact
    12661 agcaggagtt actcttctgc tttttttgat agggagatga gatgacaaga attgaagcag
    12721 tgaaacaaaa ggcaattcta gaggtggcag aaagtctagg ttattcattt aaacacctat
    12781 cagggcaagt ctatgaacat ccagaacacg attcctttag gatttttgcg gacaccaata
    12841 cctttaaatg gttttcacgt gacgtacagg gagatgtgat tgattttgtt cagttaatga
    12901 cgggagtgtc ttttaaaaaa gccctgtctt accttgaaac tggagacttt gaacaagcta
    12961 aaatcgtaga agagacttac caaccctttc gttattatct aagagaagaa ccatttgacc
    13021 aagcacggat atacctgaat gacattcgtg gtttaagtga cgagactatc aatgcttttg
    13081 gcagacaagg tctattagca caggctcatt atcagacaaa tacctttcag gaatcagtcc
    13141 ttgtctttaa gagttacaat catcatggcc aactagaggg ggcaagtctt caagggcttg
    13201 tcaaagataa tcagagacat gatcgaggtt acctcaagaa aatcatgaaa gactctcatg
    13261 gttatatagg gatgagtttt gacataggaa agcctaaacg ccttatcttt tgtgaatcgg
    13321 tgattgatat gatgagctat tatcaactcc atcagaagca gttatcagat gttcgtttgg
    13381 tttctatgga aggcttaaaa ctctctgtga ttgcgtatca gactttacga ttagcagctg
    13441 aggaacaagg caaacttgag tttttagata ctgtcaaacc aagtcgatta acgcattacc
    13501 ttcatgctat gcaagagacg actactttct ttcagatgca cacagggtta ttaaccttag
    13561 ctgttgataa tgatgaagca gggagagatt tttgtcagaa attatctgag aaaggactta
    13621 ccattgaaac agactgtcca ccattacagg aactggaaac taaagcagat tggaatgata
    13681 ttgtaaaata tcaaaataat tattctctaa aagatgtgat ccaatcggcc aagttacaag
    13741 ttatccgaag caatcctccg cctagaaaaa ataccgcttt agagttgtga taacaaaatc
    13801 aagtttctta gattaatcta gaaagtgata aggaggacac cctatgagtg tgattgaacg
    13861 cttagctgaa agagtagcta ggcaagagga aaaagttgcg aaagaaacgg aaaaattaga
    13921 aacttatcgc agtcaattac aaacagcgat gtatcaagcc tttatcaaac gccaacaaag
    13981 tagtccctgg acgtttgatg aagcattgac gcaggccttt ggccaagatg aacaagaact
    14041 aaaactatca gacactagaa atgaggaata acacatgaca aaagattgga cctttgacca
    14101 acccttagat gacaacacac cgacatcttc cacagaagaa cgtgcgaaga ttgcagcact
    14161 atttcataaa gaaaaccaag agggcactga agatgttgac tatgtggcag cctttgaaat
    14221 ggaacaacaa aaagctaagg agaaatccgt ttcacaacca aaaactcaag agcaatccac
    14281 acctaaagag gtgtcctcct ctaacattac aaacgactac aagcaacatc tagctgatgt
    14341 gatggctcag aataatgaag acattcttca aagtcagaag aaaatcgaag agttgcacca
    14401 gttgattgat gacaaaaata agcaaaataa gaaattacaa gccatttcag cagctattga
    14461 tgacttgtaa gtgaggcagt cccttacaaa ggctgctttt tataaggaga taagatgaag
    14521 ttattcaaaa agtaaacgca aaatcaagat acttttaagc gtcttattta tcgggttatc
    14581 aggaatgtct gaatcggact tacataaggt caaccaatta taagatgtcg tttttgacgc
    14641 tacaagtcaa actaaccgag atgaaaaaat gtctcctgaa actttgccaa tagaacccta
    14701 tcctagatga gaccattact gaagctaaga atatattgaa gactgagcaa cttgaaaagc
    14761 ggatagagca gtttaggcag gcgaagaaac ctaaaaatta gtaaaaaaga ttaggcattg
    14821 tgatgaaggc ctaatctttt tgtctgatac ttgttgttcg ctgatacaca tatttttttg
    14881 tcaatttact atcatttagg ttttctatgt caaagatgaa ataatgatca cgattgtctt
    14941 tagcattttc tttattgagc ttgaaatagt ttttagcaga tttcgccatt gccaacatga
    15001 tatcatctgt tagaaaagtc agtggtgtat caagtgctga gtagcgatag aagtcacttt
    15061 caaatttacg gtaattatca ctgaagtagt ccatctgtaa ttcgttttta taaaagtcaa
    15121 gctgattcat ggtagacctc ctcaactaat gtgatagcta gaatatcttc taaagcgata
    15181 gcgatatgtc cgtcattggt ttttagaatg acctcatttg ttgaaagagt cggaatggtt
    15241 ccgataatag tttgatagtc attttcctgt cttctagtca cctgtatggt caattgatta
    15301 gcgtaactct gactgagtaa cattaatttt tgattcagca ataggtcaga aaggtagctg
    15361 acttgcttat catcatctga taaggcagag gtatgttccg ataaaaagaa ccccatccac
    15421 ttttgcatgt taacgtcttg atagtctctt gcggattgaa atggtaagta tgatcggtca
    15481 atcattgtaa tccctccaag ccacctgctg agtggcctcc tattagttta cttcttgcaa
    15541 tattcctaga actgtctaag agggcagttc ctttttgaac cgctaaaaaa ccgaattggt
    15601 ctctaatatg gtcaatagtt tgttgtaact tttcttcttt ttcggttgct tcgatatcat
    15661 caaataatga gattaaggca tagctttcat cgacaaatcc tgagtaattg actgcaatac
    15721 cccgaacggc tcctgacgtg tattttttac gaaaaagtgt tagcacggta tcggtaagca
    15781 gtcgtgtatg attagtaggt tctatcttca tttgagcgtt gattggctgt ttcatttctg
    15841 ttttagagta ggtcacaaag atggaaacaa tagtagcttt ctgatgttct cgcctcattc
    15901 ggatggcaac ttgttcagcc atttcactaa gaacaatctc aatatcacgc tgcttgacat
    15961 agtcacgagg tagcacctga gagttgccaa gcccgtgtga ctttggttta tagggttgat
    16021 gaacattact ctcgtcaaca ccgttagcat gaaaccacaa ctggagtcca acctttccaa
    16081 attctttttt caatcgatca ggattgctat tggctagttc cttgatagag gtaatcccta
    16141 gtttgtgaag gcgtttctcg gttctagaac caattcccca aaaatcagtt agatgaggga
    16201 ttgaccagac ttttgtttct acatcttcgt aggaccaatt ggcacgcatg gtaggtgtac
    16261 gcttggcttc attgtctaga gcgagtttgg ccaataatgg gttagcgtta ctcataccaa
    16321 tggtagaata gataccagtc tttttccaga tgtcatgttg tagtttggca gagaccacat
    16381 ctaattttgc ttttctatcc atctgtttat cacttacaaa gtaattgagt gaggaggtta
    16441 aatcataaac ccttcatcaa tggagtaggg gagaatatct tcaggagccg cataatcttg
    16501 gaaaatatgt tgaatgtca
//
