Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000561.1:
Cluster 1RiPP116519

BGC0000561, thermophilin 1277 biosynthetic gene cluster from Streptococcus thermophilus. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: thermophilin 1277

Class-specific details

Biosynthetic class(es):
RiPP
RiPP subclass:
Lanthipeptide

Gene cluster description

thermophilin 1277 (BGC0000561). Gene Cluster 1. Biosynthetic class = RiPP. GenBank AB434921. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

tepA leader / core peptide, putative Class II
MMNATENQIFVETVSDQELEMLIGG - ADRGWIKDhbLDhbKDCPNVIDhaDhaICAGDhbIIDhbACKNCA

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Homologous known gene clusters

Literature references

1. Kabuki T et al. (2009) A unique lantibiotic, thermophilin 1277, containing a disulfide bridge and two thioether bridges. J Appl Microbiol 106(3):853-62. doi: 10.1111/j.1365-2672.2008.04059.x.