BGC0000572 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000572 (Burkholderia thailandensis E444)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	lassopeptide	1	22,410	High	capistruin	ribosomal:unmodified

BGC0000572 - Region 1 - lassopeptide

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Location: 1 - 22,410 nt. (total: 22,410 nt) Show pHMM detection rules used

Region on contig edge.

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Lasso peptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 22,411
Label		BGC0000572

Tailoring functions

Hydrolases: hydrolase

BTJ_875: asparagine synthase (glutamine-hydrolyzing)

smcogs: SMCOG1177: asparagine synthase (glutamine-hydrolyzing)

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000572.5	1.00	ribosomal	capistruin	Burkholderia thailandensis E444
BGC0000571.3	0.52	ribosomal	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000517.4	0.38	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0002144.3	0.37	ribosomal	phazolicin	Rhizobium sp. Pop5
BGC0001229.4	0.36	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0002747.3	0.34	ribosomal	lentinulin A	Lentinula edodes
BGC0002110.3	0.33	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0002323.2	0.33	ribosomal	nisin J	Staphylococcus capitis
BGC0000626.3	0.33	ribosomal	thuricin	Bacillus thuringiensis
BGC0001640.3	0.30	ribosomal	kocurin	Kocuria rosea

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000572.5	1.00	ribosomal	capistruin	Burkholderia thailandensis E444
BGC0000571.3	0.52	ribosomal	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000517.4	0.38	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0002144.3	0.37	ribosomal	phazolicin	Rhizobium sp. Pop5
BGC0001229.4	0.36	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0002747.3	0.34	ribosomal	lentinulin A	Lentinula edodes
BGC0002110.3	0.33	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0002323.2	0.33	ribosomal	nisin J	Staphylococcus capitis
BGC0000626.3	0.33	ribosomal	thuricin	Bacillus thuringiensis
BGC0001640.3	0.30	ribosomal	kocurin	Kocuria rosea

Similar known clusters from MIBiG 4.0

Lasso peptide predictions

Lassopeptide(s) for BTJ_873

BTJ_873

Leader:

MVRLLAKLLRSTIHGSNGVSLDAVSSTH

Full core:

GTPGFQTPDARVISRFGFN

Putative macrolactam:

GTPGFQTPD

antiSMASH-DB 4.0 matches for BTJ_873

100.0%

NC_006350.1and 95 others:

NC_007651.1 Lassopeptides: BTH_RS33970_lassopeptideNC_009074.1 Lassopeptides: BURPS668_RS38190_lassopeptideNC_012695.1 Lassopeptides: GBP346_RS40425_lassopeptideNC_021173.1 Lassopeptides: BTI_RS33305_lassopeptideNC_021884.1 Lassopeptides: BDL_RS40525_lassopeptideNC_022659.1 Lassopeptides: BBK_RS39480_lassopeptideNZ_CM003194.1 Lassopeptides: BBMA_RS39310_lassopeptideNZ_CM003196.1 Lassopeptides: BBL_RS38140_lassopeptideNZ_CM011864.1 Lassopeptides: EGT86_RS01660_lassopeptideNZ_CP004001.1 Lassopeptides: BBJ_RS39765_lassopeptideNZ_CP004003.1 Lassopeptides: BBS_RS39380_lassopeptideNZ_CP004089.1 Lassopeptides: BTL_RS33420_lassopeptideNZ_CP004377.1 Lassopeptides: BBU_RS38735_lassopeptideNZ_CP008726.1 Lassopeptides: DM82_RS35940_lassopeptideNZ_CP008777.1 Lassopeptides: DP50_RS39400_lassopeptideNZ_CP008780.1 Lassopeptides: DP51_RS38350_lassopeptideNZ_CP008909.1 Lassopeptides: DP65_RS39245_lassopeptideNZ_CP009151.1 Lassopeptides: X995_RS39770_lassopeptideNZ_CP009153.1 Lassopeptides: X978_RS39760_lassopeptideNZ_CP009157.1 Lassopeptides: X994_RS42670_lassopeptideNZ_CP009161.1 Lassopeptides: X988_RS39935_lassopeptideNZ_CP009162.1 Lassopeptides: X993_RS39150_lassopeptideNZ_CP009235.1 Lassopeptides: Y028_RS39500_lassopeptideNZ_CP009271.1 Lassopeptides: Y603_RS39035_lassopeptideNZ_CP009474.1 Lassopeptides: BG19_RS39100_lassopeptideNZ_CP009478.1 Lassopeptides: BG16_RS40710_lassopeptideNZ_CP009535.1 Lassopeptides: BG97_RS40135_lassopeptideNZ_CP009549.1 Lassopeptides: BW21_RS37025_lassopeptideNZ_CP009551.1 Lassopeptides: BG24_RS40205_lassopeptideNZ_CP009555.1 Lassopeptides: BG90_RS35245_lassopeptideNZ_CP010017.1 Lassopeptides: BTM_RS36120_lassopeptideNZ_CP012041.1 Lassopeptides: TR70_RS38735_lassopeptideNZ_CP012515.1 Lassopeptides: AM256_RS38900_lassopeptideNZ_CP013386.1 Lassopeptides: WS70_RS08835_lassopeptideNZ_CP013389.1 Lassopeptides: WS71_RS26230_lassopeptideNZ_CP016638.1 Lassopeptides: A7U58_RS38975_lassopeptideNZ_CP017046.1 Lassopeptides: BGI49_RS39180_lassopeptideNZ_CP018383.1 Lassopeptides: BOC43_RS39140_lassopeptideNZ_CP071746.1 Lassopeptides: J3B45_RS10065_lassopeptideNZ_CP071749.1 Lassopeptides: J3B47_RS10230_lassopeptideNZ_CP071751.1 Lassopeptides: J3C54_RS15805_lassopeptideNZ_CP071761.1 Lassopeptides: J3L14_RS10150_lassopeptideNZ_CP116601.1 Lassopeptides: AQ936_RS20060_lassopeptideNZ_CSLP01000001.1 Lassopeptides: AKT31_RS38150_lassopeptideNZ_CWJC01000004.1 Lassopeptides: AFJ43_RS39230_lassopeptideNZ_KN150858.1 Lassopeptides: DO71_RS39720_lassopeptideNZ_KN150860.1 Lassopeptides: DO62_RS40040_lassopeptideNZ_KN150927.1 Lassopeptides: DP42_RS41440_lassopeptideNZ_KN150935.1 Lassopeptides: DO65_RS40480_lassopeptideNZ_KN150937.1 Lassopeptides: DO63_RS39450_lassopeptideNZ_KN150939.1 Lassopeptides: DO66_RS40420_lassopeptideNZ_KN150942.1 Lassopeptides: DP56_RS40490_lassopeptideNZ_KN150943.1 Lassopeptides: DP57_RS40565_lassopeptideNZ_KN150953.1 Lassopeptides: DO72_RS42385_lassopeptideNZ_KN150964.1 Lassopeptides: DP44_RS40805_lassopeptideNZ_KN150978.1 Lassopeptides: DP49_RS43175_lassopeptideNZ_KN150983.1 Lassopeptides: DP62_RS40350_lassopeptideNZ_KN322988.1 Lassopeptides: X883_RS38640_lassopeptideNZ_KN322990.1 Lassopeptides: Y038_RS39280_lassopeptideNZ_KN322992.1 Lassopeptides: Y037_RS39890_lassopeptideNZ_KN322996.1 Lassopeptides: X888_RS38645_lassopeptideNZ_KN322998.1 Lassopeptides: X881_RS39400_lassopeptideNZ_KN323000.1 Lassopeptides: X885_RS38545_lassopeptideNZ_KN323004.1 Lassopeptides: X895_RS39640_lassopeptideNZ_KN323008.1 Lassopeptides: X880_RS39170_lassopeptideNZ_KN323010.1 Lassopeptides: X983_RS39015_lassopeptideNZ_KN323012.1 Lassopeptides: X879_RS39965_lassopeptideNZ_KN323016.1 Lassopeptides: X898_RS39165_lassopeptideNZ_KN323020.1 Lassopeptides: X890_RS39265_lassopeptideNZ_KN323024.1 Lassopeptides: X897_RS40015_lassopeptideNZ_KN323027.1 Lassopeptides: X900_RS39855_lassopeptideNZ_KN323035.1 Lassopeptides: X887_RS39400_lassopeptideNZ_KN323039.1 Lassopeptides: X882_RS38380_lassopeptideNZ_KN323044.1 Lassopeptides: Y049_RS00535_lassopeptideNZ_KN323051.1 Lassopeptides: Y046_RS41170_lassopeptideNZ_KN323058.1 Lassopeptides: Y045_RS39980_lassopeptideNZ_KN323063.1 Lassopeptides: Y602_RS40130_lassopeptideNZ_KN323065.1 Lassopeptides: Y597_RS39655_lassopeptideNZ_KN323067.1 Lassopeptides: Y601_RS38805_lassopeptideNZ_KN323068.1 Lassopeptides: Y048_RS40685_lassopeptideNZ_KN323078.1 Lassopeptides: Y030_RS40080_lassopeptideNZ_KN323082.1 Lassopeptides: X984_RS39595_lassopeptideNZ_KN323085.1 Lassopeptides: X896_RS40285_lassopeptideNZ_KN323088.1 Lassopeptides: Y036_RS41600_lassopeptideNZ_KN323130.1 Lassopeptides: Y598_RS39000_lassopeptideNZ_KN360700.1 Lassopeptides: Y039_RS38840_lassopeptideNZ_LGKL01000002.1 Lassopeptides: ADU20_RS39595_lassopeptideNZ_LNJS01000001.1 Lassopeptides: WS92_RS34990_lassopeptideNZ_LWKL01000051.1 Lassopeptides: A4G86_RS17265_lassopeptideNZ_LWKM01000058.1 Lassopeptides: A4G85_RS30190_lassopeptideNZ_OW622535.1 Lassopeptides: NIU15_RS22665_lassopeptideNZ_UUTE01000002.1 Lassopeptides: EFD44_RS04885_lassopeptideNZ_UVEY01000011.1 Lassopeptides: EF100_RS16095_lassopeptideNZ_UVFO01000015.1 Lassopeptides: EFN82_RS18460_lassopeptideNZ_UVGN01000023.1 Lassopeptides: EF147_RS25210_lassopeptide

Lassopeptides: BPS_RS09525_lassopeptide

GTPGFQTPDARVISRFGFN

94.7%

NZ_CP013424.1and 1 other:

NZ_CP013457.1 Lassopeptides: WT60_RS33570_lassopeptide

Lassopeptides: WS86_RS34200_lassopeptide

GTPGFQTPDARVISRFGFN

GTPGFQTPD RVISRFGFN

GTPGFQTPDNRVISRFGFN

33.3%

NZ_JABEOU010000012.1:

Lassopeptides: HKX06_RS03315_lassopeptide

GTPGFQTPDARVISRFGFN

G PGFQT + G

GRPGFQTELGVIAQPLGIE

with 6 more sequence matches

28.6%

NZ_CAKJTI010000013.1and 6 others:

NZ_CP031443.1 Lassopeptides: MLA2C4_RS19250_lassopeptideNZ_FWZD01000067.1 Lassopeptides: BACERE00177_RS21400_lassopeptideNZ_JACYOF010000019.1 Lassopeptides: IGI01_RS27610_lassopeptideNZ_NTYE01000016.1 Lassopeptides: CN490_RS29030_lassopeptideNZ_NUEY01000038.1 Lassopeptides: CN888_RS28205_lassopeptideNZ_QOSD01000019.1 Lassopeptides: DN410_RS14275_lassopeptide

Lassopeptides: LRP84_RS13300_lassopeptide

PGFQTPDA

PG +TPDA

PGHKTPDA

28.6%

NZ_CM000754.1and 17 others:

NZ_CP020723.1 Lassopeptides: B7P25_RS28625_lassopeptideNZ_CP023179.1 Lassopeptides: CK938_RS28520_lassopeptideNZ_CP032365.1 Lassopeptides: D4A37_RS18780_lassopeptideNZ_CP041063.1 Lassopeptides: FJM75_RS10710_lassopeptideNZ_CP085399.1 Lassopeptides: LIS81_RS18060_lassopeptideNZ_FMBE01000013.1 Lassopeptides: CCY88_RS31005_lassopeptideNZ_FMJI01000046.1 Lassopeptides: CCY61_RS30520_lassopeptideNZ_FMZR01000002.1 Lassopeptides: BLS53_RS31385_lassopeptideNZ_FTLZ01000002.1 Lassopeptides: BW973_RS28715_lassopeptideNZ_JH791975.1 Lassopeptides: IEI_RS31960_lassopeptideNZ_JYPF01000002.1 Lassopeptides: TU50_RS30650_lassopeptideNZ_NUFG01000001.1 Lassopeptides: CN694_RS29875_lassopeptideNZ_NURJ01000008.1 Lassopeptides: COE89_RS29040_lassopeptideNZ_PIYQ01000023.1 Lassopeptides: CW365_RS28935_lassopeptideNZ_QOSC01000009.1 Lassopeptides: DN392_RS14315_lassopeptideNZ_VDNI01000012.1 Lassopeptides: FSV62_RS19525_lassopeptideNZ_WBPF01000005.1 Lassopeptides: F8162_RS06315_lassopeptide

Lassopeptides: BTHUR0009_RS30905_lassopeptide

PGFQTPDA

PG +TPDA

PGLKTPDA

24.0%

NZ_CP024848.1and 5 others:

NZ_CP030028.1 Lassopeptides: DOE78_RS20570_lassopeptideNZ_JAIEZS010000055.1 Lassopeptides: K0820_RS18465_lassopeptideNZ_JAQQWU010000003.1 Lassopeptides: PQ511_RS07455_lassopeptideNZ_JH792165.1 Lassopeptides: IIO_RS35460_lassopeptideNZ_KI632505.1 Lassopeptides: V180_RS32040_lassopeptide

Lassopeptides: CUC15_RS18285_lassopeptide

PGFQTPDA

PG +TPDA

PGIKTPDA

24.0%

NZ_CP041405.1and 2 others:

NZ_CP094446.1 Lassopeptides: L3476_RS19330_lassopeptideNZ_CP106992.1 Lassopeptides: NDS46_RS02035_lassopeptide

Lassopeptides: FLT43_RS18930_lassopeptide

PGFQTPDA

PG TPDA

PGLSTPDA

24.0%

NZ_CP095550.1:

Lassopeptides: MVE64_RS05235_lassopeptide

PGFQTPDA

PG +TPDA

PGIRTPDA

23.8%

NZ_CP069296.1:

Lassopeptides: JOJ89_RS10650_lassopeptide

PGFQTPDA

PG ++PDA

PGIKSPDA

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lasso peptides

Core peptide predictions

BTJ_873 - Class II: Cleavage pHMM score: 0.40; RODEO score: 22; Monoisotopic mass: 2048.0 Da; Molecular weight: 2049.2 Da; Number of bridges: 0