BGC0000573 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000573 (Caulobacter sp. K31)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	lassopeptide	1	22,399	High	caulonodin I/caulonodin II	ribosomal:unmodified

BGC0000573 - Region 1 - lassopeptide

Download region GenBank file

Download region SVG

Location: 1 - 22,399 nt. (total: 22,399 nt) Show pHMM detection rules used

Region on contig edge.

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Lasso peptides

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 22,400
Label		BGC0000573

Tailoring functions

Hydrolases: hydrolase

Caul_5191: asparagine synthase (glutamine-hydrolyzing)

smcogs: SMCOG1177: asparagine synthase (glutamine-hydrolyzing)

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000573.3	1.00	ribosomal	caulonodin I, caulonodin II	Caulobacter sp. K31
BGC0000580.3	0.64	ribosomal	xanthomonin II, xanthomonin I	Xanthomonas gardneri ATCC 19865
BGC0001786.3	0.58	ribosomal	subterisin	Novosphingobium subterraneum
BGC0000576.3	0.56	ribosomal	rubrivinodin	Rubrivivax gelatinosus IL144
BGC0000577.3	0.55	ribosomal	sphingonodin II	Sphingobium japonicum UT26S
BGC0000570.3	0.53	ribosomal	astexin-1	Asticcacaulis excentricus CB 48
BGC0000574.3	0.48	ribosomal	caulosegnin I, caulosegnin II, caulosegnin III	Caulobacter segnis ATCC 21756
BGC0002384.3	0.22	NRPS	lysocin E	Lysobacter sp.

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000573.3	1.00	ribosomal	caulonodin I, caulonodin II	Caulobacter sp. K31
BGC0000580.3	0.64	ribosomal	xanthomonin II, xanthomonin I	Xanthomonas gardneri ATCC 19865
BGC0001786.3	0.58	ribosomal	subterisin	Novosphingobium subterraneum
BGC0000576.3	0.56	ribosomal	rubrivinodin	Rubrivivax gelatinosus IL144
BGC0000577.3	0.55	ribosomal	sphingonodin II	Sphingobium japonicum UT26S
BGC0000570.3	0.53	ribosomal	astexin-1	Asticcacaulis excentricus CB 48
BGC0000574.3	0.48	ribosomal	caulosegnin I, caulosegnin II, caulosegnin III	Caulobacter segnis ATCC 21756
BGC0002384.3	0.22	NRPS	lysocin E	Lysobacter sp.

Similar known clusters from MIBiG 4.0

Lasso peptide predictions

Lassopeptide(s) for Caul_5193

Caul_5193

Leader:

MQRIIDETTDGLIELGAASVQTQ

Full core:

GDVLFAPEPGVGRPPMG

Putative macrolactam:

GDVLFAPE

Caul_5193

Cleaved off residues:

LSED

antiSMASH-DB 4.0 matches for Caul_5193

31.8%

NZ_QRBE01000001.1:

Lassopeptides: DWU98_RS22405_lassopeptide

GDVLFAPEPGV

G VLF P+PG

GGVLFKPQPGT

30.0%

NZ_JACCCA010000013.1and 1 other:

NZ_JACHCM010000004.1 Lanthipeptides: allorf_497513_497614_lanthipeptide

Lanthipeptides: allorf_082880_082981_lanthipeptide

GDVLFAPE

G VLFAP

GKVLFAPS

16.7%

NZ_LR655208.1:

Lanthipeptides: FS985_RS23945_lanthipeptide

APEPGVGRP

A PG GRP

ATSPGTGRP

Lassopeptide(s) for Caul_5194

Caul_5194

Leader:

MERIEDHIDDELIDLGAASVETQ

Full core:

GDVLNAPEPGIGREPTG

Putative macrolactam:

GDVLNAPE

Caul_5194

Cleaved off residues:

LSRD

antiSMASH-DB 4.0 matches for Caul_5194

52.9%

NZ_QDKQ01000044.1:

Lassopeptides: DDF67_RS12730_lassopeptide

GDVLNAPEPGIGREPTG

G L E GIGR+P G

GSDLPTSEVGIGRQPAG

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lasso peptides

Core peptide predictions

Caul_5193 - Class II: Cleavage pHMM score: 13.50; RODEO score: 21; Monoisotopic mass: 1676.8 Da; Molecular weight: 1677.9 Da; Number of bridges: 0
Caul_5194 - Class II: Cleavage pHMM score: 14.90; RODEO score: 20; Monoisotopic mass: 1659.8 Da; Molecular weight: 1660.8 Da; Number of bridges: 0