BGC0000582: cypemycin biosynthetic gene cluster from Streptomyces sp. OH-4156
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Location: 1 - 12,148 nt. (total: 12,148 nt).
This entry is originally from NCBI GenBank HQ148718.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000582
Short description cypemycin biosynthetic gene cluster from Streptomyces sp. OH-4156
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Remarks "Paper reporting the cypemycin structure is not archived in PubMed:\nMinami Y, et al. (1994) Structure of cypemycin, a new peptide antibiotic. Tetrahedron Lett 35:8001-8004"
Biosynthetic class(es)
  • RiPP (Linaridin)
Loci NCBI GenBank: HQ148718.1
Compounds
  • cypemycin
Species Streptomyces sp. OH-4156 [taxonomy]
References
Chemical products information
cypemycin
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C99H154N24O24S1
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADR72961.1
 57 - 3308 (-) putative regulatory protein
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  • ADR72962.1
 3882 - 4076 (+) cypemycin structural protein
  • Unknown
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  • ADR72963.1
 4191 - 5945 (+) hypothetical protein
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  • ADR72964.1
 5935 - 6495 (+) unknown
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  • ADR72965.1
 6492 - 7064 (+) HFCD family decarboxylase
  • Tailoring (Unknown)
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  • ADR72966.1
 7057 - 7794 (+) SAM-dependent methyltransferase
  • Tailoring (Methylation)
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  • ADR72967.1
 7791 - 8423 (+) ABC transporter ATP binding subunit
  • Transport
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  • ADR72968.1
 8420 - 9970 (+) putative transmembrane pore
  • Transport
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  • ADR72969.1
 10053 - 12074 (+) DUF255 family protein
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RiPP-specific information
Subclass Linaridin
Cyclic? yes
Precursor genes
ADR72962.1
Leader sequence: MRSEMTLTSTNSAEALAAQDFANTVLSAAAPGFHADCETPAM
Core sequences:
  • ATPATPTVAQFVIQGSTICLVC
Crosslinks:
  • 19x22 (Thioether)
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: SJOI7JSMELHUIOC3HESCTFXV, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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