BGC0000583: grisemycin biosynthetic gene cluster from Streptomyces griseus subsp. griseus NBRC 13350
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Location: 7,570,210 - 7,576,934 nt. (total: 6,725 nt).
This entry is originally from NCBI GenBank AP009493.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000583
Short description grisemycin biosynthetic gene cluster from Streptomyces griseus subsp. griseus NBRC 13350
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
AP009493.1
7570210 - 7576934
via Knock-out studies, Heterologous expression, Gene expression correlated with compound production
Compounds
  • grisemycin
Species Streptomyces griseus subsp. griseus NBRC 13350 [taxonomy]
References
Chemical products information
grisemycin Evidence: NMR [1]
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C86H137N21O21S1
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SGR_6361
  • BAG23190.1
 7570210 - 7570842 (-) putative ABC transporter ATP-binding protein
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    • SGR_6362
    • BAG23191.1
    		 7570839 - 7571576 (-) putative methyltransferase
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      • SGR_6363
      • BAG23192.1
      		 7571569 - 7572141 (-) putative phosphopantothenoylcysteine synthetase/decarboxylase
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        • SGR_6364
        • BAG23193.1
        		 7572138 - 7572704 (-) hypothetical protein
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          • SGR_6365
          • BAG23194.1
          		 7572694 - 7574451 (-) hypothetical protein
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            • SGR_6366
            • BAG23195.1
            		 7575285 - 7576934 (+) putative SARP-family pathway specific regulatory protein
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              Biosynthesis information
              Annotation changelog

              Entry version: next

              Date
              Changes
              Submitters
              Reviewers
              2024-04-28
              MIBiG v4 annotathon
              • (ID: DG4477I3NOB53FE2RWVWGK44)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

              Entry version: 4

              Date
              Changes
              Submitters
              Reviewers
              2022-10-07
              Update chemical activity to schema version 2.11
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

              Entry version: 3

              Date
              Changes
              Submitters
              Reviewers
              2022-09-15
              Corrected NCBI accession to match gene naming in the reference
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              2022-09-15
              Updated bioactivity data
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

              Entry version: 2

              Date
              Changes
              Submitters
              Reviewers
              2019-10-16
              Migrated from v1.4
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

              Entry version: 1

              Date
              Changes
              Submitters
              Reviewers
              2015-06-12
              Submitted
              • (ID: SJOI7JSMELHUIOC3HESCTFXV)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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