LOCUS       BGC0000594              6812 bp    DNA     linear   BCT 21-JUL-2011
DEFINITION  Planktothrix agardhii NIVA-CYA 126/8 putative methyltransferase
            gene, complete cds; microviridin biosynthetic gene cluster, complete
            sequence; and short chain dehydrogenase gene, complete cds.
ACCESSION   BGC0000594
VERSION     BGC0000594
KEYWORDS    .
SOURCE      Planktothrix agardhii NIVA-CYA 126/8
  ORGANISM  Planktothrix agardhii NIVA-CYA 126/8
            Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
            Oscillatoriales; Microcoleaceae; Planktothrix.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:53:54
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6812
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..798
                     /NRPS_PKS="Domain: oMT (17-254). E-value: 4e-79. Score:
                     257.8. Matches aSDomain: nrpspksdomains_ACC54546.1_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 196; E-value: 1.2e-59)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF1; AdpE-like"
                     /product="putative methyltransferase"
                     /protein_id="ACC54546.1"
                     /transl_table=11
                     /translation="MDKNEWISKFDSLILNPSTREIYGQNEFFNVGYWQSDTQNQEESC
                     FNLMEKLLEFIPEKQGNILDVGSGLGATTSYLLNYYSSAAIVGINISPTQIERSILNAP
                     DCKFLLMDAVNIEFEDNFFDNIICVESAFYFNTREKFLKEAWRVLKPGGNLVLSDMSFA
                     TTEYLGDWTVPQANTVKDIAEYQNIYQQLGFQQLQFVEATEECWFRHFRHLKSWLGEEF
                     QSEKMDEETYNANVNAIDNLLSSSAITYLLVAAKKSFRVSQVK"
     source          1..6812
                     /db_xref="taxon:388467"
                     /mol_type="genomic DNA"
                     /organism="Planktothrix agardhii NIVA-CYA 126/8"
                     /strain="NIVA-CYA 126/8"
     protocluster    1..6812
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5455:5947]"
                     /cutoff="20000"
                     /detection_rule="(mvd or mvnA)"
                     /neighbourhood="10000"
                     /product="microviridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5456..5947
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(mvd or mvnA)"
                     /neighbourhood="10000"
                     /product="microviridin"
                     /protocluster_number="1"
     cand_cluster    1..6812
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(mvd or mvnA)"
                     /kind="single"
                     /product="microviridin"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..6812
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000594"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..6812
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="microviridin"
                     /region_number="1"
                     /rules="(mvd or mvnA)"
                     /subregion_numbers="1"
                     /tool="antismash"
     aSDomain        52..762
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACC54546.1_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="4.00E-79"
                     /label="ACC54546.1_oMT.1"
                     /locus_tag="ACC54546.1"
                     /protein_end="254"
                     /protein_start="17"
                     /score="257.8"
                     /tool="antismash"
                     /translation="STREIYGQNEFFNVGYWQSDTQNQEESCFNLMEKLLEFIPEKQGN
                     ILDVGSGLGATTSYLLNYYSSAAIVGINISPTQIERSILNAPDCKFLLMDAVNIEFEDN
                     FFDNIICVESAFYFNTREKFLKEAWRVLKPGGNLVLSDMSFATTEYLGDWTVPQANTVK
                     DIAEYQNIYQQLGFQQLQFVEATEECWFRHFRHLKSWLGEEFQSEKMDEETYNANVNAI
                     DNLLSSSAITYLLVA"
     gene            842..2635
                     /gene="mvdA"
     CDS             842..2635
                     /codon_start=1
                     /gene="mvdA"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 112.9; E-value:
                     3.2e-34)"
                     /gene_kind="transport"
                     /note="ABC transporter"
                     /product="MvdA"
                     /protein_id="ACC54547.1"
                     /transl_table=11
                     /translation="MQTQVPPDKTITNPLSSLTRFLQDVKIIAQPYWYPTELNGRAFSD
                     VICSWGMLALMVLSIILLVSVDAFASFWNRHVLDIVIEQRDLSKYLETLWLSSFLIVLI
                     TCLVALAQFVRKKVALDWYKWLSNNTLKQYLSDRAYYKIGFTSGLENPDQRLSQEIEPI
                     TTITLRFLTTLLEKSLQMITFLVILWTISQEITIYLVIYTISGNFIAVYLTQELNKINR
                     AELNSKAEYNYALTHVRDHAESIAFFRGEEQEEKIIERRFNNIIKNAEQRINWERFQDL
                     FNRGYQSAISVFSMFILTPMFIQDKIDFGEISQASLCCFLFSNALGQLVSEWGTSAKLS
                     NYIERLASFSDGLKTVSLEPKNLGRITTVEDNRLAFENFTLQTPDYEKVIVENLSLSVP
                     SGKGLLIVGPSGRGKSSLLRAIAGLWNAGTGRLVRPALEEMLFLPQRPYIILGTLRDQI
                     LYPHTTDQIADQELEKILEKVNLQHLLTQTNVFDKQVNWENILSLGEQQRLAFARMLVT
                     RPSFAILDEATSALDLINEESLYQQLQQTQTTFISVGHRESLFNYHQWVLELAENSRWQ
                     FLSVEDYQQQKFGAINFLKKS"
     misc_feature    842..5947
                     /note="microviridin biosynthetic gene cluster"
     gene            2731..3270
                     /gene="mvdB"
     CDS             2731..3270
                     /codon_start=1
                     /gene="mvdB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 81.1;
                     E-value: 1.5e-24)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative acetyltransferase; GNAT family related to
                     RimL"
                     /product="MvdB"
                     /protein_id="ACC54548.1"
                     /transl_table=11
                     /translation="MGDLVTKRLRLVPFKLPIVQAAMIGDIELGKVLGVTVLSDWIDQE
                     FYDNLPEIANILNKSPLQGEWGWGNLVIQQAENTLIGHVMLKIIPDIPDPTGSPTGALE
                     IGYEIAPSYRRQGYGSEATKVVLDWAFSQPAVEKVTAGCDADNIGSKRLLEKIGMQHTK
                     TLANGQVLVWELSRSS"
     gene            3337..4311
                     /gene="mvdC"
     CDS             3337..4311
                     /codon_start=1
                     /gene="mvdC"
                     /note="cyclization protein; amide bond formation; similar
                     to RimK ATP-binding proteins"
                     /product="MvdC"
                     /protein_id="ACC54549.1"
                     /transl_table=11
                     /translation="MSLSRDVVLLITHSGDFFTIDRVIEALLKKGVQPFRFDTDQFPLN
                     VQLTANFGKSNSDHQLEYNGNSISTKQVQAVWLRRIWEPDFQELDPQYQQACAKESKAT
                     LNGFWDSLRDANWVDHLAQIEAASNKLLQLRLASEVGFTIPQTLITNKAEAAREFFQQV
                     NGKMVSKLLTALSRSMESTSFFLYTSLVKEEYLQDAESLRYCPMVFQEQIFKQQELRVI
                     YVNGKVFVGALNASVYEDSTVDWRAPGIEVGAWQNHQLPEELIRRLQTFMGELGLLFGA
                     FDFILTPSGDYVFLEVNPGGEWGMLERDLDLPISQAIADTLIP"
     gene            4347..5339
                     /gene="mvdD"
     CDS             4347..5339
                     /codon_start=1
                     /gene="mvdD"
                     /note="cyclization protein; ester bond formation; similar
                     to RimK ATP-binding proteins"
                     /product="MvdD"
                     /protein_id="ACC54550.1"
                     /transl_table=11
                     /translation="MTVLIFTFSNDNESIPLVVKAIEAKGEKAFRFDTDRFPTEVKLDI
                     YSGDFEGGIVTDGEHKLDLSEVSSVWYRRMRYGAKLPDSMDQQFREASLKECRLTVRGL
                     IASLPGFHFDPMINVDRANNKQLQLQIARQLGLLTPRTLTSNNPEAVKQFAQDCKEQGI
                     VTKMLSQFAIYGENKEENVVFTSPVTDDDLDNLEGLSFCPMTFQENVPKALELRTIIVG
                     KQVFTAAINSQQLDGATYDWRKEGRALHEKWQAYNLPEDIEKKLLQLTAYFGLNYGAID
                     IIVTPDGRHVFLEINPVGEFFWLELFAPYFPISQAIAEILLTPTNQKPF"
     gene            5456..5602
                     /gene="mvdE"
     CDS             5456..5602
                     /codon_start=1
                     /gene="mvdE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvnA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvd"
                     /gene_kind="biosynthetic"
                     /note="microviridin K precursor"
                     /product="MvdE"
                     /protein_id="ACC54551.1"
                     /sec_met_domain="mvnA (E-value: 8.1e-27, bitscore: 82.3,
                     seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="mvd (E-value: 2e-11, bitscore: 33.2,
                     seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKNVKVSAPKAVPFFARFLAEQAVEANNSNSAPYGNTMKYPSDW
                     EEY"
     gene            5795..5947
                     /gene="mvdF"
     CDS             5795..5947
                     /codon_start=1
                     /gene="mvdF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvnA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvd"
                     /gene_kind="biosynthetic"
                     /note="unknown microviridin prepeptide"
                     /product="MvdF"
                     /protein_id="ACC54552.1"
                     /sec_met_domain="mvnA (E-value: 9.1e-29, bitscore: 88.5,
                     seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="mvd (E-value: 4.8e-13, bitscore: 38.4,
                     seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKNIKVSTGSAVPFFARFLSEQDTETGDSTSTDIPTIWTFKWPS
                     DWEDS"
     CDS             6075..6812
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     104.8; E-value: 8.9e-32)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF2; AdpF-like"
                     /product="short chain dehydrogenase"
                     /protein_id="ACC54553.1"
                     /transl_table=11
                     /translation="MFESLSGKKVVIIGMNSGVDLAIANKILELGAKVVLSHPSPEKLN
                     QAIGLISVEIEAKTVNILNQDSVNTFFEEVGNFDHLVVTAIGDRNMPRSLLAEMTTETA
                     QGGMDKFWGTFFAVRAGLKTIATDGSITLTSSVSMFKSSKLGGISVIAAANSAVAAFGR
                     SLALEIAPIRVNVIAPGLIEDTSIWSSQGESERSDLNKWAIAALPVAHLGQPEALAQAV
                     LSLMTNPYMTGVILPVEGGVTLI"
ORIGIN
        1 atggataaaa atgaatggat tagtaaattt gatagtttaa ttctcaatcc ttcaactcgg
       61 gaaatttatg gtcaaaacga gttttttaat gtgggttact ggcaatcaga tacccaaaat
      121 caagaggaat cttgttttaa tttgatggaa aaacttttag aatttattcc cgaaaagcag
      181 ggaaatattc tcgatgttgg ctccggtttg ggcgcaacaa ccagttacct cctcaattat
      241 tattcctcgg cagcaattgt gggaattaat atttcgccta cacaaattga aagaagtatt
      301 ttgaacgctc ctgactgcaa attcctgtta atggatgcgg tcaatattga atttgaggat
      361 aatttttttg ataatattat ttgtgtagaa tcagctttct attttaatac tagagaaaag
      421 tttctaaaag aagcttggcg ggtgctgaaa ccggggggaa atttagttct ctcggatatg
      481 agttttgcca caacagaata tttgggtgat tggactgttc cccaagctaa tacggttaaa
      541 gatattgccg aatatcaaaa tatttaccaa cagttaggat ttcaacagtt acaattcgtg
      601 gaggcgacgg aggaatgttg gttccgacat tttcgacatc taaaatcttg gctgggagaa
      661 gaatttcaat cagaaaagat ggacgaagaa acctataatg ctaatgttaa tgctatagat
      721 aatttattaa gttcttcagc aataacttat ttattggtag cagcaaagaa atcatttaga
      781 gttagtcaag ttaaataatt tataacttat ccggtgtcaa taattaccag ctttttagga
      841 tatgcaaact caagttcccc ctgacaaaac tatcaccaat cccctttcat ctttgactcg
      901 atttttgcaa gatgttaaaa ttattgctca accttactgg tatcccacag agttaaatgg
      961 acgggcattt tccgatgtga tttgttcctg gggaatgttg gctctaatgg ttttaagcat
     1021 aattttgcta gtgagtgtcg atgcttttgc cagcttctgg aatcgccatg tcctagatat
     1081 tgtgattgaa caaagagacc tttctaagta tcttgagact ctctggctgt ctagcttttt
     1141 gattgtgctg atcacctgtt tagtcgccct ggctcaattt gttaggaaaa aagttgctct
     1201 tgattggtat aagtggctaa gtaataacac cttaaaacaa tatttgagcg atcgcgccta
     1261 ttataaaatt ggttttacat cgggtttaga aaatcctgac caacgtttat cccaagaaat
     1321 tgaaccgatt accaccataa ccttgaggtt tttaacaacc ttattagaaa agagtctgca
     1381 aatgatcact tttctggtta ttctttggac aatttcccaa gagattacta tttatctagt
     1441 tatctatacc atttctggta actttattgc ggtgtattta acccaagagt taaataagat
     1501 taatcgagcg gaacttaact ctaaggctga atataattat gccctaaccc atgtccgaga
     1561 tcatgcggaa tccattgctt tttttcgagg ggaggaacag gaagaaaaaa tcatcgaacg
     1621 cagatttaat aatattatca aaaatgctga acaaagaatt aattgggaga gatttcagga
     1681 tctttttaat cgtggctatc agtctgcgat tagtgttttt tcgatgttta ttctgacacc
     1741 aatgttcatt caagataaaa ttgattttgg agaaattagt caagccagtt tatgctgttt
     1801 tctcttttct aatgccttgg gacaactggt aagtgagtgg ggaacttcag caaaattatc
     1861 taattatatt gagcgtttag cctccttttc tgatggctta aaaacagtga gcctagaacc
     1921 aaaaaacctc ggtaggatta caacagtaga agacaaccgt ttagcttttg agaattttac
     1981 tctacaaacc ccagattatg agaaagtaat tgttgaaaat ttatccctat cagttccatc
     2041 gggaaaaggt ttattaattg ttggccctag tggtcgcggg aaaagttctt tgctacgagc
     2101 gatcgcaggt ttatggaatg caggaaccgg gcgtttagtg cgtcctgctc tcgaagaaat
     2161 gttattttta ccccaacgtc cttatattat tttgggcact ctgcgtgacc aaatccttta
     2221 tccccatacc acggatcaaa ttgctgatca agaactggaa aaaatcctag aaaaagtcaa
     2281 ccttcaacat ttattaactc aaactaatgt ttttgataaa caagtaaatt gggaaaatat
     2341 tttatcatta ggagaacaac agcgactagc ctttgcccga atgttagtga cccgtcccag
     2401 tttcgctata ttagatgaag ctaccagtgc tttagattta attaatgaag aaagtttgta
     2461 tcaacaattg cagcaaaccc agacaacttt tattagtgta ggacatcgtg aaagtctatt
     2521 taattatcat caatgggtac tagaacttgc agaaaattct cgttggcaat ttttgagtgt
     2581 tgaagactac caacagcaaa aattcggggc gatcaatttt cttaaaaaat cttaaacttc
     2641 cagataataa gtctcaatag gttgtaatat ttcatcctag aggttgggtc tgccaaccct
     2701 ctttgcgctc gattaggatt aatatataac atgggtgatc ttgttaccaa acgattacgt
     2761 ttagtgcctt ttaaattgcc aattgtacaa gcggcaatga ttggcgatat tgaattagga
     2821 aaagttctag gtgttacagt tttatctgac tggattgatc aagaatttta tgataacttg
     2881 ccagaaattg ccaatatact gaacaaaagt ccattacaag gagaatgggg atggggaaat
     2941 ttagtgattc aacaagcaga aaatacccta attggtcacg ttatgcttaa aattattcca
     3001 gatatccccg accccacagg ttcccccaca ggagcactgg aaattggcta tgaaatcgct
     3061 ccctcctatc gacgacaggg atacggatct gaagcgacaa aagtagtgtt agactgggca
     3121 ttctctcaac ctgctgtgga aaaagtgacg gcgggctgtg atgctgataa tattggttcc
     3181 aaaagattgc tagaaaaaat cggaatgcag cacacaaaaa ccctagccaa tggtcaagta
     3241 ttagtttggg aattatcgcg ttcttcttag tttcaaaatt ctctttttaa agctataggc
     3301 aaaactcaaa atctaaatta cggagaaaat agttctatgt ctttgtctcg tgatgttgtt
     3361 ttattaatta ctcatagtgg ggattttttc accattgatc gagtcataga agccctatta
     3421 aaaaaaggcg tgcaaccctt tcgttttgat acggatcaat ttccccttaa tgtccaatta
     3481 actgccaatt ttggcaaatc aaacagcgat catcaactgg aatataatgg taattctatt
     3541 agcacaaaac aggtacaagc ggtttggcta cgacggatct gggagcctga ttttcaggaa
     3601 ttagaccccc aatatcaaca ggcttgtgcc aaggaatcaa aggcaacttt aaacggcttt
     3661 tgggacagtc tgagagatgc taattgggtt gatcatttag cacaaattga ggcggcaagt
     3721 aataaactac tgcaattaag attagcctca gaagtaggat ttactattcc gcaaacattg
     3781 atcacaaata aagctgaagc cgcacgggaa ttttttcaac aagttaacgg caaaatggtg
     3841 agtaagctat taacggctct ttctcgtagt atggaaagca cttctttttt cctttatact
     3901 agcttagtta aagaggaata tttacaagat gcggagtcat tacgttattg tccaatggtt
     3961 ttccaagaac aaatttttaa gcaacaggaa ttgcgagtta tttatgtgaa tggtaaggta
     4021 tttgtggggg cgttaaatgc ttctgtttat gaagattcta ccgtagattg gcgtgctcct
     4081 ggtatcgagg ttggtgcttg gcaaaatcat caacttcctg aagaattaat ccgtcgtctt
     4141 cagactttta tgggtgaatt ggggctgtta tttggagctt ttgattttat tctcacgccg
     4201 tcgggagatt atgtcttttt agaagttaat cctggcggtg aatggggaat gttggaaagg
     4261 gatttagatt tgccgatttc tcaagcgatc gccgataccc taattcccta aaatttacta
     4321 cttaaccatt attattgagg agatttatga cggttttaat tttcactttc agcaacgata
     4381 atgaaagtat tcccctggtt gttaaagcta ttgaagctaa gggtgaaaaa gcctttcgtt
     4441 ttgataccga tcgctttccc acggaagtaa aactcgatat ttattcgggt gattttgagg
     4501 ggggaatagt taccgatgga gaacataaat tagacttaag tgaagtctcc tcggtttggt
     4561 atcggcgcat gagatatggt gctaaacttc ctgatagtat ggatcagcaa tttcgggaag
     4621 cgtctttaaa agaatgtcgc cttaccgtcc gaggattaat tgctagtcta ccaggtttcc
     4681 attttgatcc gatgattaac gttgatcggg ctaataataa gcaactgcaa ttacaaattg
     4741 cccgacaatt gggtttatta actccccgga ctttgacctc aaataatccc gaagctgtca
     4801 aacaatttgc ccaggattgt aaagagcaag gaattgttac taaaatgctc tctcaatttg
     4861 cgatttatgg cgaaaataaa gaagaaaatg tcgtgtttac cagtcctgta accgatgatg
     4921 atttagataa tttggaaggg ctaagttttt gtccgatgac ttttcaagaa aatgtaccta
     4981 aagccctaga attaaggaca attattgtag gaaaacaggt atttactgcc gccattaact
     5041 ctcaacaatt agacggagct acctatgatt ggcggaaaga aggaagggct ttacatgaaa
     5101 aatggcaagc ctataattta cccgaagata ttgagaaaaa actgctgcaa ctgacggctt
     5161 attttggctt aaactatgga gctattgata ttattgtcac tcccgatggt cggcacgttt
     5221 tcctagaaat taatcccgtt ggcgagtttt tctggttgga attatttgct ccctatttcc
     5281 ctatttccca ggcgatcgct gaaattctgc tcactcctac aaaccagaaa ccattttagt
     5341 gattcaggat acttttttaa taaaagttaa tcatttgttc tggatttccc ttgacatatc
     5401 ctgttcgtcc gtagtatctt ggtcgcaggt caatattgca aaaggaactt aactgatgtc
     5461 caaaaatgtt aaagtctctg cgcccaaagc agtccccttc tttgctcgtt tcttagcaga
     5521 gcaagccgtg gaagctaaca attctaattc tgctccttac ggtaatacta tgaagtatcc
     5581 ttccgattgg gaagaatatt aaatagataa gagcaatctt aatcgaaaat taagggagta
     5641 gcagttattt aataactaaa agctactccc tatttgattg cttgattttt ttaagattgg
     5701 atatcaaact acttatacaa ttgatttaga cttgctatat tgggtcgatt cgtgatagaa
     5761 tcccaacaat tagctttctg aaaagtaaac tactatgtct aaaaatatca aagtatcgac
     5821 cggatcagca gtccccttct ttgctcgttt cttgtcagaa caagacacag aaactggtga
     5881 ttctacttct accgatatcc ccacgatctg gactttcaag tggccttccg attgggaaga
     5941 tagttaagta gaccagagca atcttgatcg aaaattaagg gagtagcagt tatttaataa
     6001 ctaaaagcta ctcccgattt ttgtttaaat attaagttaa agtagtttta tattgtgatc
     6061 cccaggagaa aataatgttt gagtcgctat caggaaaaaa ggtagttatt attggcatga
     6121 attcgggagt tgacctggcg atcgccaata agatattaga attgggggca aaagttgtac
     6181 tttctcaccc atctccagaa aaattaaatc aggcgatcgg attaatttcg gtcgagattg
     6241 aagcaaaaac cgttaacatt ttgaatcaag attcagttaa tacttttttt gaggaagtgg
     6301 gaaactttga tcatttagtc gtaactgcta tcggagacag aaatatgccc cgatcgctat
     6361 tagcagaaat gaccacagaa acggctcaag gtggcatgga caagttctgg ggaacatttt
     6421 ttgctgtccg tgccgggttg aaaaccatag ccaccgatgg ctccattacc ctaacctcca
     6481 gtgtttctat gtttaaatct tcaaaactgg gagggatttc cgtgatcgcc gccgccaata
     6541 gtgccgtggc cgcatttggc cgatcgctgg ccttagaaat cgcacccatt cgggtcaatg
     6601 tgattgctcc tggactgata gaggatacta gcatctggag cagtcaaggc gagtctgaac
     6661 gttcagacct gaacaagtgg gcgatcgcag ccttacctgt ggcccatctg gggcaaccag
     6721 aggcactagc gcaggcggta ttaagtttga tgactaatcc ctatatgacc ggggtgattt
     6781 tacctgttga gggtggagtc accttgatct aa
//
