Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000595.1:
Cluster 1RiPP121771

BGC0000595, SCO-2138 biosynthetic gene cluster from Streptomyces coelicolor. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: SCO-2138
Exact molecular mass: 2138.19 Da (M+)
Molecular activity: Unknown

Class-specific details

Biosynthetic class(es):
RiPP subclass:
Other (linear)
Peptides in this cluster:
RiPP core peptide sequence(s): MNLLTDILAGLVHFVGWLV
Leader peptide length: 30
Follower peptide length: 19
Peptidase(s) involved in precursor cleavage:

Gene cluster description

SCO-2138 (BGC0000595). Gene Cluster 1. Biosynthetic class = RiPP. GenBank NC_003888, positions 2616326-2638096. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Sequence-based prediction
Contact for this cluster:Alexey Melnik (UCSD)

Literature references

1. Kersten RD et al. (2011) A mass spectrometry-guided genome mining approach for natural product peptidogenomics. Nat Chem Biol 7(11):794-802. doi: 10.1038/nchembio.684.