Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000597.1:
Cluster 1RiPP110846

BGC0000597, SWA-2138 biosynthetic gene cluster from Streptomyces sp. e14. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: SWA-2138
Exact molecular mass: 2138.18 Da (M+)
Molecular activity: Unknown

Class-specific details

Biosynthetic class(es):
RiPP subclass:
Proteusin (linear)
Peptides in this cluster:
RiPP core peptide sequence(s): MNLITDVLAGLVHFIGWLV
Leader peptide length: 19
Follower peptide length: -1
Peptidase(s) involved in precursor cleavage:

Gene cluster description

SWA-2138 (BGC0000597). Gene Cluster 1. Biosynthetic class = RiPP. GenBank NZ_GG753626, positions 1489807-1500652. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Sequence-based prediction
Contact for this cluster:Alexey Melnik (UCSD)

Literature references

1. Kersten RD et al. (2011) A mass spectrometry-guided genome mining approach for natural product peptidogenomics. Nat Chem Biol 7(11):794-802. doi: 10.1038/nchembio.684.