BGC0000600 - 1 region(s) - antiSMASH results

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	sactipeptide	1	8,141	Medium	thurincin H	ribosomal:RiPP

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 8,142
Label		BGC0000600

Tailoring functions

Hydrolases: protease

thnP: alkaline serine protease, subtilase family

smcogs: SMCOG1075: alkaline serine protease, subtilase family

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000600.3	0.83	ribosomal	thurincin H	Bacillus thuringiensis
BGC0000622.5	0.49	ribosomal	megacin	Bacillus megaterium
BGC0002667.2	0.45	ribosomal	estericin A	Clostridium estertheticum
BGC0000504.5	0.43	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002700.2	0.42	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0001555.4	0.41	ribosomal	colicin V	Escherichia coli chi7122
BGC0001639.3	0.40	ribosomal	klebsidin	Klebsiella pneumoniae
BGC0002111.3	0.40	ribosomal	andalusicin A, andalusicin B	Bacillus thuringiensis serovar andalousiensis NRRL B-23139
BGC0000584.5	0.40	ribosomal	colicin V	Escherichia coli

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000600.3	0.83	ribosomal	thurincin H	Bacillus thuringiensis
BGC0000622.5	0.49	ribosomal	megacin	Bacillus megaterium
BGC0002667.2	0.45	ribosomal	estericin A	Clostridium estertheticum
BGC0000504.5	0.43	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002700.2	0.42	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0001555.4	0.41	ribosomal	colicin V	Escherichia coli chi7122
BGC0001639.3	0.40	ribosomal	klebsidin	Klebsiella pneumoniae
BGC0002111.3	0.40	ribosomal	andalusicin A, andalusicin B	Bacillus thuringiensis serovar andalousiensis NRRL B-23139
BGC0000584.5	0.40	ribosomal	colicin V	Escherichia coli

Similar known clusters from MIBiG 4.0

Sactipeptide predictions

Sactipeptide(s) for allorf_3502_3627

allorf_3502_3627

Leader:

MKSYLIAVYL

Core:

VKLLFIIYNVNCVWCVWCALHNITLIDREVV

antiSMASH-DB 4.0 matches for allorf_3502_3627

51.6%

NZ_JYPH01000039.1:

Sactipeptides: allorf_12067_12156_sactipeptide

10

VNCVWCVWCALHNITLIDREVV

31

+NCVWCV C ITLIDREVV

1

INCVWCVCCVCRTITLIDREVV

22

15.4%

NZ_CP102267.1:

Lanthipeptides: allorf_0904640_0904792_lanthipeptide

1

VKLLFIIYNVNCVWCV

16

+ +FI+ V C +CV

7

TEYVFILGEVRCTYCV

22

12.5%

NZ_SDJV01000024.1:

Lanthipeptides: ES032_RS12705_lanthipeptide

4

LFIIYNVNCVWCVWCALHNI

23

+++ NV+ VWC + +

15

VYVTANVSSVWCAGATVGAV

34

MIBiG 4.0 matches for allorf_3502_3627

12.9%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

18

CALHNIT

24

CA +NI+

1

CAWYNIS

7

Sactipeptide(s) for thnA1

thnA1

Leader:

METPVVQPRD

Core:

WTCWSCLVCAACSVELLNLVTAATGASTAS

antiSMASH-DB 4.0 matches for thnA1

100.0%

NZ_CM000752.1and 15 others:

NZ_CM000752.1 Sactipeptides: BTHUR0007_RS37430_sactipeptideNZ_JABGBR020000007.1 Sactipeptides: HOV72_RS15955_sactipeptideNZ_JABGBR020000007.1 Sactipeptides: HOV72_RS15950_sactipeptideNZ_JYPH01000039.1 Sactipeptides: TU52_RS33370_sactipeptideNZ_JYPH01000039.1 Sactipeptides: TU52_RS33365_sactipeptideNZ_NJPZ01000025.1 Sactipeptides: CE087_RS29070_sactipeptideNZ_NJPZ01000025.1 Sactipeptides: CE087_RS29065_sactipeptideNZ_NJPZ01000025.1 Sactipeptides: CE087_RS29060_sactipeptideNZ_NUBO01000020.1 Sactipeptides: CN575_RS31360_sactipeptideNZ_NUBO01000020.1 Sactipeptides: CN575_RS31355_sactipeptideNZ_NUBO01000020.1 Sactipeptides: CN575_RS31350_sactipeptideNZ_NUUQ01000016.1 Sactipeptides: COI65_RS30820_sactipeptideNZ_NUUQ01000016.1 Sactipeptides: COI65_RS30815_sactipeptideNZ_NUUQ01000016.1 Sactipeptides: COI65_RS30810_sactipeptideNZ_NUXK01000018.1 Sactipeptides: COJ27_RS31850_sactipeptide

Sactipeptides: BTHUR0007_RS37435_sactipeptide

1

WTCWSCLVCAACSVELLNLVTAATGASTAS

30

WTCWSCLVCAACSVELLNLVTAATGASTAS

1

WTCWSCLVCAACSVELLNLVTAATGASTAS

30

26.7%

NC_014551.1and 5 others:

NC_017188.1 Lanthipeptides: BAMTA208_RS20930_lanthipeptideNZ_CP032146.1 Lanthipeptides: D2M30_RS20755_lanthipeptideNZ_CP062984.1 Lanthipeptides: IL989_RS03870_lanthipeptideNZ_DF836084.1 Lanthipeptides: CMW1_RS20395_lanthipeptideNZ_KQ236689.1 Lanthipeptides: AD710_RS19840_lanthipeptide

Lanthipeptides: BAMF_RS41655_lanthipeptide

16

LLNLVTAATGASTAS

30

LL L+T G+ST S

1

LLTLITTIVGSSTIS

15

26.7%

NC_018089.1and 13 others:

NC_018089.1 Lanthipeptides: SMUGS5_RS08730_lanthipeptideNZ_CP043405.1 Lanthipeptides: FY406_RS04350_lanthipeptideNZ_CP043405.1 Lanthipeptides: FY406_RS04350_lanthipeptideNZ_CP044493.1 Lanthipeptides: FSA40_RS09070_lanthipeptideNZ_CP044493.1 Lanthipeptides: FSA40_RS09070_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS00320_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS00320_lanthipeptideNZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03990_lanthipeptideNZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03990_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08125_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08125_lanthipeptideNZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05520_lanthipeptideNZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05520_lanthipeptide

Lanthipeptides: SMUGS5_RS08730_lanthipeptide

11

ACSVELLNLVTAATGASTA

29

AC++ ++ + A TG STA

4

ACAIGVVGITVAVTGISTA

22

with 1 more sequence matches

23.3%

NZ_QKUF01000004.1:

Lanthipeptides: EI42_RS08635_lanthipeptide

2

TCWSCLVCAACS

13

TCWSC C C

7

TCWSCSRCTDCK

18

Sactipeptide(s) for thnA2

thnA2

Leader:

METPVVQPRD

Core:

WTCWSCLVCAACSVELLNLVTAATGASTAS

antiSMASH-DB 4.0 matches for thnA2

100.0%

NZ_CM000752.1and 15 others:

NZ_CM000752.1 Sactipeptides: BTHUR0007_RS37430_sactipeptideNZ_JABGBR020000007.1 Sactipeptides: HOV72_RS15955_sactipeptideNZ_JABGBR020000007.1 Sactipeptides: HOV72_RS15950_sactipeptideNZ_JYPH01000039.1 Sactipeptides: TU52_RS33370_sactipeptideNZ_JYPH01000039.1 Sactipeptides: TU52_RS33365_sactipeptideNZ_NJPZ01000025.1 Sactipeptides: CE087_RS29070_sactipeptideNZ_NJPZ01000025.1 Sactipeptides: CE087_RS29065_sactipeptideNZ_NJPZ01000025.1 Sactipeptides: CE087_RS29060_sactipeptideNZ_NUBO01000020.1 Sactipeptides: CN575_RS31360_sactipeptideNZ_NUBO01000020.1 Sactipeptides: CN575_RS31355_sactipeptideNZ_NUBO01000020.1 Sactipeptides: CN575_RS31350_sactipeptideNZ_NUUQ01000016.1 Sactipeptides: COI65_RS30820_sactipeptideNZ_NUUQ01000016.1 Sactipeptides: COI65_RS30815_sactipeptideNZ_NUUQ01000016.1 Sactipeptides: COI65_RS30810_sactipeptideNZ_NUXK01000018.1 Sactipeptides: COJ27_RS31850_sactipeptide

Sactipeptides: BTHUR0007_RS37435_sactipeptide

1

WTCWSCLVCAACSVELLNLVTAATGASTAS

30

WTCWSCLVCAACSVELLNLVTAATGASTAS

1

WTCWSCLVCAACSVELLNLVTAATGASTAS

30

26.7%

NC_014551.1and 5 others:

NC_017188.1 Lanthipeptides: BAMTA208_RS20930_lanthipeptideNZ_CP032146.1 Lanthipeptides: D2M30_RS20755_lanthipeptideNZ_CP062984.1 Lanthipeptides: IL989_RS03870_lanthipeptideNZ_DF836084.1 Lanthipeptides: CMW1_RS20395_lanthipeptideNZ_KQ236689.1 Lanthipeptides: AD710_RS19840_lanthipeptide

Lanthipeptides: BAMF_RS41655_lanthipeptide

16

LLNLVTAATGASTAS

30

LL L+T G+ST S

1

LLTLITTIVGSSTIS

15

26.7%

NC_018089.1and 13 others:

NC_018089.1 Lanthipeptides: SMUGS5_RS08730_lanthipeptideNZ_CP043405.1 Lanthipeptides: FY406_RS04350_lanthipeptideNZ_CP043405.1 Lanthipeptides: FY406_RS04350_lanthipeptideNZ_CP044493.1 Lanthipeptides: FSA40_RS09070_lanthipeptideNZ_CP044493.1 Lanthipeptides: FSA40_RS09070_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS00320_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS00320_lanthipeptideNZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03990_lanthipeptideNZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03990_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08125_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08125_lanthipeptideNZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05520_lanthipeptideNZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05520_lanthipeptide

Lanthipeptides: SMUGS5_RS08730_lanthipeptide

11

ACSVELLNLVTAATGASTA

29

AC++ ++ + A TG STA

4

ACAIGVVGITVAVTGISTA

22

with 1 more sequence matches

23.3%

NZ_QKUF01000004.1:

Lanthipeptides: EI42_RS08635_lanthipeptide

2

TCWSCLVCAACS

13

TCWSC C C

7

TCWSCSRCTDCK

18

Sactipeptide(s) for thnA3

thnA3

Leader:

METPVVQPRD

Core:

WTCWSCLVCAACSVELLNLVTAATGASTAS

antiSMASH-DB 4.0 matches for thnA3

100.0%

NZ_CM000752.1and 15 others:

NZ_CM000752.1 Sactipeptides: BTHUR0007_RS37430_sactipeptideNZ_JABGBR020000007.1 Sactipeptides: HOV72_RS15955_sactipeptideNZ_JABGBR020000007.1 Sactipeptides: HOV72_RS15950_sactipeptideNZ_JYPH01000039.1 Sactipeptides: TU52_RS33370_sactipeptideNZ_JYPH01000039.1 Sactipeptides: TU52_RS33365_sactipeptideNZ_NJPZ01000025.1 Sactipeptides: CE087_RS29070_sactipeptideNZ_NJPZ01000025.1 Sactipeptides: CE087_RS29065_sactipeptideNZ_NJPZ01000025.1 Sactipeptides: CE087_RS29060_sactipeptideNZ_NUBO01000020.1 Sactipeptides: CN575_RS31360_sactipeptideNZ_NUBO01000020.1 Sactipeptides: CN575_RS31355_sactipeptideNZ_NUBO01000020.1 Sactipeptides: CN575_RS31350_sactipeptideNZ_NUUQ01000016.1 Sactipeptides: COI65_RS30820_sactipeptideNZ_NUUQ01000016.1 Sactipeptides: COI65_RS30815_sactipeptideNZ_NUUQ01000016.1 Sactipeptides: COI65_RS30810_sactipeptideNZ_NUXK01000018.1 Sactipeptides: COJ27_RS31850_sactipeptide

Sactipeptides: BTHUR0007_RS37435_sactipeptide

1

WTCWSCLVCAACSVELLNLVTAATGASTAS

30

WTCWSCLVCAACSVELLNLVTAATGASTAS

1

WTCWSCLVCAACSVELLNLVTAATGASTAS

30

26.7%

NC_014551.1and 5 others:

NC_017188.1 Lanthipeptides: BAMTA208_RS20930_lanthipeptideNZ_CP032146.1 Lanthipeptides: D2M30_RS20755_lanthipeptideNZ_CP062984.1 Lanthipeptides: IL989_RS03870_lanthipeptideNZ_DF836084.1 Lanthipeptides: CMW1_RS20395_lanthipeptideNZ_KQ236689.1 Lanthipeptides: AD710_RS19840_lanthipeptide

Lanthipeptides: BAMF_RS41655_lanthipeptide

16

LLNLVTAATGASTAS

30

LL L+T G+ST S

1

LLTLITTIVGSSTIS

15

26.7%

NC_018089.1and 13 others:

NC_018089.1 Lanthipeptides: SMUGS5_RS08730_lanthipeptideNZ_CP043405.1 Lanthipeptides: FY406_RS04350_lanthipeptideNZ_CP043405.1 Lanthipeptides: FY406_RS04350_lanthipeptideNZ_CP044493.1 Lanthipeptides: FSA40_RS09070_lanthipeptideNZ_CP044493.1 Lanthipeptides: FSA40_RS09070_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS00320_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS00320_lanthipeptideNZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03990_lanthipeptideNZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03990_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08125_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08125_lanthipeptideNZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05520_lanthipeptideNZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05520_lanthipeptide

Lanthipeptides: SMUGS5_RS08730_lanthipeptide

11

ACSVELLNLVTAATGASTA

29

AC++ ++ + A TG STA

4

ACAIGVVGITVAVTGISTA

22

with 1 more sequence matches

23.3%

NZ_QKUF01000004.1:

Lanthipeptides: EI42_RS08635_lanthipeptide

2

TCWSCLVCAACS

13

TCWSC C C

7

TCWSCSRCTDCK

18

Identified secondary metabolite regions using strictness 'relaxed'

Legend:

Sactipeptide(s) for allorf_3502_3627

antiSMASH-DB 4.0 matches for allorf_3502_3627

MIBiG 4.0 matches for allorf_3502_3627

Sactipeptide(s) for thnA1

antiSMASH-DB 4.0 matches for thnA1

Sactipeptide(s) for thnA2

antiSMASH-DB 4.0 matches for thnA2

Sactipeptide(s) for thnA3

antiSMASH-DB 4.0 matches for thnA3