BGC0000601: sporulation killing factor biosynthetic gene cluster from Bacillus subtilis subsp. subtilis str. 168
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Location: 213,941 - 220,032 nt. (total: 6,092 nt).
This entry is originally from NCBI GenBank AL009126.3.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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Gene details
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General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000601
Short description sporulation killing factor biosynthetic gene cluster from Bacillus subtilis subsp. subtilis str. 168
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • RiPP (Head-to-tailcyclized peptide)
Loci NCBI GenBank: AL009126.3
Compounds
  • sporulation killing factor
Species Bacillus subtilis subsp. subtilis str. 168 [taxonomy]
References
Chemical products information
sporulation killing factor [synonyms: skf]
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BSU_01910
  • CAB11984.1
  • skfA
 213941 - 214108 (+) sporulation killing factor A
  • Precursor biosynthesis
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  • BSU_01920
  • CAB11985.2
  • skfB
 214175 - 215407 (+) synthesis of sporulation killing factor A
  • Activation / processing
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  • BSU_01935
  • CAX52541.1
  • skfC
 215404 - 216894 (+) sporulation killing factor biosynthesis and export
  • Activation / processing
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  • BSU_01950
  • CAB11989.1
  • skfE
 216913 - 217632 (+) sporulation killing factor biosynthesis and export; ABC transporter (binding protein)
  • Transport
Activity assay
Heterologous expression
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  • BSU_01960
  • CAB11990.2
  • skfF
 217697 - 219040 (+) sporulation killing factor biosynthesis and export; ABC transporter (permease)
  • Transport
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  • BSU_01970
  • CAB11991.2
  • skfG
 219087 - 219602 (+) sporulation killing factor biosynthesis and export
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  • BSU_01980
  • CAB11992.2
  • skfH
 219607 - 220032 (+) sibling killing effect; sporulation killing factor biosynthesis and export
  • Activation / processing
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RiPP-specific information
Subclass Head-to-tailcyclized peptide
Cyclic? yes
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: TTYNBWNDJR6YSNQQMLZQM46S, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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