BGC0000604: GE2270A biosynthetic gene cluster from Nonomuraea sp. WU8817
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Location: 1 - 22,848 nt. (total: 22,848 nt).
This entry is originally from NCBI GenBank FJ461359.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000604
Short description GE2270A biosynthetic gene cluster from Nonomuraea sp. WU8817
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • RiPP (Thiopeptide)
Loci NCBI GenBank: FJ461359.1
Compounds
  • GE2270A
Species Nonomuraea sp. WU8817 [taxonomy]
References
Chemical products information
GE2270A
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C56H55N15O10S6
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACS83759.1
  • tpdR
 1 - 714 (+) TetR transcriptional regulator
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  • ACS83760.1
  • tpdO
 711 - 2612 (+) cyclodehydratase
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  • ACS83761.1
  • tpdP
 2609 - 5098 (+) dehydratase
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  • ACS83762.1
  • tpdQ
 5095 - 6129 (+) cytochrome P450 monooxygenase
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  • ACS83763.1
  • tpdS
 6218 - 6904 (+) hypothetical protein
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  • ACS83764.1
  • tpdT
 6947 - 8065 (+) N-methyl transferase
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  • ACS83765.1
  • tpdU
 8094 - 9338 (+) coproporphyrinogen III oxidase
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  • ACS83766.1
  • tpdA
 9462 - 9635 (+) GE2270 prepropeptide
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  • ACS83767.1
  • tpdB
 9646 - 12129 (+) dehydratase
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  • ACS83768.1
  • tpdC
 12126 - 13025 (+) dehydratase
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  • ACS83769.1
  • tpdD
 13025 - 14026 (+) hypothetical protein
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  • ACS83770.1
  • tpdE
 14023 - 15390 (+) dehydrogenase
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  • ACS83771.1
  • tpdF
 15378 - 17204 (+) hypothetical protein
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  • ACS83772.1
  • tpdG
 17201 - 18937 (+) cyclodehydratase
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  • ACS83773.1
  • tpdK
 18969 - 19337 (+) hypothetical protein
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  • ACS83774.1
  • tpdL
 19327 - 20577 (+) coproporphyrinogen III oxidase
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  • ACS83775.1
  • tpdM
 20579 - 21598 (+) O-methyl transferase
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  • ACS83776.1
  • tpdN
 22234 - 22848 (+) deaminase reductase
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RiPP-specific information
Subclass Thiopeptide
Cyclic? yes
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: O4PIO7VEX2IICIP2RGFFKN3C, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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