LOCUS       BGC0000610             34713 bp    DNA     linear   BCT 25-JUN-2014
DEFINITION  Streptomyces actuosus clone cosmid 13G2 nosiheptide biosynthetic
            gene cluster, partial sequence.
ACCESSION   BGC0000610
VERSION     BGC0000610
KEYWORDS    .
SOURCE      Streptomyces actuosus
  ORGANISM  Streptomyces actuosus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:55:37
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 34713
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     subregion       1..34713
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000610"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..34713
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="thiopeptide"
                     /product="LAP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and ((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or PF07366 or PF06968 or PF04055) or thiostrepton)"
                     /rules="((((goadsporin_like or PF00881 or TIGR03605) and
                     (YcaO or TIGR03604)) or TIGR03882 or TIGR03603 or
                     TIGR03602) and not cyanobactin_synth)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(<1..978)
                     /gene="nos1"
     CDS             complement(<1..978)
                     /codon_start=1
                     /gene="nos1"
                     /note="elongation factor G"
                     /product="Nos1"
                     /protein_id="ACR48327.1"
                     /transl_table=11
                     /translation="MATTSLDLAKVRNIGIMAHIDAGKTTTTERILFYTGVSYKIGEVH
                     DGAATMDWMEQEQERGITITSAATTCHWSLDDVDHTINIIDTPGHVDFTVEVERSLRVL
                     DGAVTVFDGVAGVEPQSETVWRQADRYGVPRICFVNKLDRTGAEFHRCVDMISDRLGAQ
                     PIVMQLPIGAEADFKGVVDLVRMKALVWSAEATKGEMYDVVDIPATHTEAAEEWRGKLL
                     EAVAENDEEIMELYLEGEEPSEEQLYAAIRRITIASGKGQGTTVTPVFCGTAFKNKGVQ
                     PLLDAVVRYLPSPVDIEAIEGHAVDNAEEVIKRKPSDEEPLAALA"
     misc_feature    <1..34546
                     /note="nosiheptide biosynthetic gene cluster"
     source          1..34713
                     /clone="cosmid 13G2"
                     /db_xref="taxon:1885"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces actuosus"
     protocluster    1..31187
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2248:21187]"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /neighbourhood="10000"
                     /product="thiopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2249..21187
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /neighbourhood="10000"
                     /product="thiopeptide"
                     /protocluster_number="1"
     cand_cluster    1..31187
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((YcaO or TIGR03604) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /detection_rules="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /kind="chemical_hybrid"
                     /product="thiopeptide"
                     /product="LAP"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..22800
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[9128:12800]"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      9129..12800
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="2"
     gene            complement(1018..1488)
                     /gene="nos2"
     CDS             complement(1018..1488)
                     /codon_start=1
                     /gene="nos2"
                     /note="30S ribosomal protein S7"
                     /product="Nos2"
                     /protein_id="ACR48328.1"
                     /transl_table=11
                     /translation="MPRKGPAPKRPVIIDPVYGSPLVTSLINKVLLNGKRSTAERIVYG
                     AMEGLREKTGNDPVITLKRALENIKPTLEVKSRRVGGATYQVPVEVKPGRANTLALRWL
                     VGYSRARREKTMTERLLNELLDASNGLGAAVKKREDTHKMAESNKAFAHYRW"
     gene            complement(1491..1862)
                     /gene="nos3"
     CDS             complement(1491..1862)
                     /codon_start=1
                     /gene="nos3"
                     /note="30S ribosomal protein S12"
                     /product="Nos3"
                     /protein_id="ACR48329.1"
                     /transl_table=11
                     /translation="MPTIQQLVRKGRQDKVEKNKTPALEGSPQRRGVCTRVFTTTPKKP
                     NSALRKVARVRLTSGIEVTAYIPGEGHNLQEHSIVLVRGGRVKDLPGVRYKIIRGSLDT
                     QGVKNRKQARSRYGAKKEK"
     gene            complement(2249..2704)
                     /gene="nosA"
     CDS             complement(2249..2704)
                     /codon_start=1
                     /gene="nosA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: thio_amide"
                     /gene_kind="biosynthetic"
                     /note="hypothetical protein"
                     /product="NosA"
                     /protein_id="ACR48330.1"
                     /sec_met_domain="thio_amide (E-value: 2.5e-37, bitscore:
                     117.7, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEHPAQQLYCTVVLWDLSRSAATVASLRAYLRDHAVDAYTTVPG
                     LRQKTWISSTGPEGEQWGAVYLWDSPEAAYGRPPGVSKVVELIGYRPTERRYYSVEAAT
                     EGPAAAAAPFGKGLGLAFDPASPEPLTRPQEFVPPGADAFIPSRPPA"
     gene            complement(2701..4068)
                     /gene="nosB"
     CDS             complement(2701..4068)
                     /codon_start=1
                     /gene="nosB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 300.5; E-value: 2.9e-91)"
                     /gene_kind="biosynthetic-additional"
                     /note="cytochrome P450"
                     /product="NosB"
                     /protein_id="ACR48331.1"
                     /sec_met_domain="p450 (E-value: 2.8e-21, bitscore: 66.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDESPTYPFEQKCPFAPPDELVRRRDEAPVSQIRLANGATAWLVT
                     RHDDVRTVLTDPRFSRAAIRAGALRGGPPGPGGPGGSAEGAPQGGWPGGPGGSAGGAPQ
                     GGWPGGVPGPGGPGGASVGPGAPGKGPGQRFDFGMALADPERHARWRRTLATVLTPRHA
                     ESLRKAVGQAVDEVLDGLAEAGPDPVDLVSGFAYQVPVRVLCELFDLPEELRPGLWGWA
                     AQVRAAAPSTAAFGAAMGALFGVARQLVEKELAAPGDGLIGSLIAGLDEDARPSADELV
                     STVVLLATAGYESTAVQFANGLLALFQHPDQLARLRDGTVTEAAAVEEILRYAQAGTGF
                     AGTTVTTEEVTLGGITLPEGATVFISLDSAARDERHVDRPDTFDLARGAARTHLTFGAG
                     AHYCLGSSLARVELQEGFGRLLRRFPALTPAADPAAVEFTANLFHRYPRELKAVLR"
     gene            complement(4083..5309)
                     /gene="nosC"
     CDS             complement(4083..5309)
                     /codon_start=1
                     /gene="nosC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 386; E-value: 3.3e-117)"
                     /gene_kind="biosynthetic-additional"
                     /note="cytochrome P450"
                     /product="NosC"
                     /protein_id="ACR48332.1"
                     /sec_met_domain="p450 (E-value: 2.8e-32, bitscore: 102.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIEARTYPFTRHTPFEMPEEFAWLRENRPIAQVRLATGDTAWLI
                     TRYEDVRTALTDPRFSRTINREGAARVDTGFQADADSPVFNFGGSISEPPGHTRWRRLV
                     NQAFTARHAESMRPAVAAHTDALLDDLESAGGRFDLMADYAYQLPIRVICDLLGLEQTA
                     RPEFSALAAQITRRDFTSSFVEFGQALQAIGRYAIGLIVRKRQNLGDDLLSTLIGLTDE
                     EDGRLSNEELVSTVILLLMAGYESTAVQLGNAFYALFRDPSQMRRLREEPALIGQAVEE
                     ILRYAQMGTGYAIAKFTTEDVELSGGTVPAGSTVFVSLASANRDEKVFGEDADRFDVGR
                     GCAHRQTAFGYGPHYCLGAALARVEMQEGIARMLNRFPDLRFDGPDLDGVPLASNLFTF
                     YPAELPVRI"
     gene            complement(5328..6365)
                     /gene="nosD"
     CDS             complement(5328..6365)
                     /codon_start=1
                     /gene="nosD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /note="dehydratase"
                     /product="NosD"
                     /protein_id="ACR48333.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3e-54, bitscore:
                     175.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAPETGPWHSLHLHRYAGQDAFLVDGLAPVLAPLHASGALESSF
                     FLRYWQGGHHIRLRLRPAAHDPEQAARTVREVADRLAGHLAAHPGGYGDLDPEEFREAQ
                     LTMAALESEATGELLPPDTVHPARYEPEYGKYGGPEGVAVAERFFDRSSAVALSALRAI
                     GDRPARRLGAAFTMTLRGLCAARLSPPAMAGFLAHYCAVWSPYVFDSFLDTWPELLDQR
                     RGPAAAHLRPLLAAAQPPDDPYGRAVGEAWQALHTAADTVLPAVTLGGPDAPAERRRQI
                     VLLSYLHTHNNRLGLIPEQEAFLGYLGHHVVADCAGLAPDAGLLDRVRDHRRERLAAHL
                     PSGQH"
     gene            complement(6352..9114)
                     /gene="nosE"
     CDS             complement(6352..9114)
                     /codon_start=1
                     /gene="nosE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     53.4; E-value: 1.6e-16)"
                     /gene_kind="biosynthetic"
                     /note="dehydratase"
                     /product="NosE"
                     /protein_id="ACR48334.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6.6e-45, bitscore:
                     144.0, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGAPDAAGAPDGFSPYYLYRRGTLGPSELAALTPARTWALLAEA
                     EETRQRREELRGRLEDALHAAVPELPADRRHELLRLRRDIHNDRVPGVPDAARLLDPAS
                     RELLEDWLRHRAEGNRLHKEAEAALAAELDAGRRALAAIATGEFFQRGLQLSDERTWRT
                     VTEWAADPFSARRKPSKRRRAENTLTSFAYRVALKPSPFASFTEIGAAPWTPAGDGTAP
                     ADRPPARPVQARLSAGLLSWMTYELHRLDRADELMRIRLNHSLLVREEQALCVRRAPDG
                     APEAAYGTAQVVTARDTGLLRLLRSLLADGGLPERELRERLAAAGLSPQAAATALDKLV
                     RAGICERGLGIPDQHPRPALAVAQRLRTLDTDQAGRCAVVFERLQAAEDAFPAAPVRRR
                     AALLAEIREQVAVFVEAVGCRAPAPEAMRSVVYEDVGTREPAHSWHPDLLHANRWALEL
                     FQRIVPVLDDASVEKAGLYAFFARHFGAADGDGDVPFIEFYRRFAALPPAEASAVASGV
                     GDPHSDRIRRLRADFADLLRTELRAHDSAHTGALRLDAERLRAFADRLPAEVTPWRSTA
                     YRMQFTAEPERPYAVVNGVTTGHGVFFSRFCDLLEPDGPHEWSLTEALRGHIARTTPRQ
                     CDITAVLGLNFNLHPRLSPYELVYPGSVPRAADEHTLTLADLAVRADPARRTLALVSTR
                     DGQPLDLVPLNFLYPAAAPGLYRLLCAFAPTRTYRGGLWDQLDRADAEAGRAAGRTGVP
                     ATHRSLPRVLLGDLVLDRASWRLPAADVPDTDGLERQEAAALASFDRWLGQRGIPRHTF
                     FRLTTPPPVPAGERDLLAETRQWALEARTARLHKPHYLDARNPFLLQVFARRLAEAGPD
                     ATVTFQECLPHAGDLDGRTSGAEEFFVEYTLGTPAPAGTQATEDAHARP"
     gene            complement(9129..10778)
                     /gene="nosF"
     CDS             complement(9129..10778)
                     /codon_start=1
                     /gene="nosF"
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     PF00881"
                     /gene_kind="biosynthetic"
                     /note="NADH oxidase"
                     /product="NosF"
                     /protein_id="ACR48335.1"
                     /sec_met_domain="PF00881 (E-value: 9e-08, bitscore: 23.1,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTDEAYTYTTGLRLDPRSANPDGWRVDWADGPWPVKVYSGARRL
                     PLRPDGPPPLAALHRLLHGGFAVSRIRTDPSGGIAATPADPRPHHGPEVQLRRPVPSGG
                     AMYPTEVYAALTATGQVCHYDPYRHELTVLAGGDAAARLRAALHLPTEAAPAAVLVLTS
                     RFWKNFYKYGDFATRLGLVDAGVALGRAARLARAEWEHAEVRTVFDDEAVHACLGLDGE
                     EENAWAAVTLGPYLPYRADTGGPDAPPRPALLERSRTVRRSDRFTAFQRAAREDTSTAA
                     PARPPEDAVPATAPGPVPGDAGPAAAPGPVHEDAVSAAAPRPVPGDAVPVGPVPLPAPR
                     ALDLLAAETAARRFSRGRLFTGAEADGEALAGVLGQAAEALRALAGAGADGPAGWAART
                     RLYCAVHRVRGVPPGWYRYAHELGALLPVGEGTGPGSARRVQEALFAASFNAELAAFTV
                     HPVTPADWRPAGGPRAYRAQQLAVGAAIEAVTLAAAAEGLSGHAVLGFDVTRIDTAYGL
                     DGGADTDGGTQAQICVGAVRPDPNWEIAVMPR"
     gene            complement(10830..12800)
                     /gene="nosG"
     CDS             complement(10830..12800)
                     /codon_start=1
                     /gene="nosG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     YcaO"
                     /gene_kind="biosynthetic"
                     /note="putative cyclodehydratase"
                     /product="NosG"
                     /protein_id="ACR48336.1"
                     /sec_met_domain="YcaO (E-value: 3.2e-73, bitscore: 238.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 7.9e-97, bitscore:
                     315.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTATTPQPRTGPAGPPVVVGRGVLAEHLVRRLGRDDTPDPDGGA
                     RFGRSSGATVLVAGLDGLGEFQDTVVDCLATGRSLLFVGSWRSLVYIGPVWRPGTQGCP
                     RCLVTRTANSPFGPGLEGDSLAESWPHGADVRIWGPGVLRLVEEYVRARLASCKGPAGP
                     ADGRVLVLDGAAGTVEQQTLLPDSGCPNCGSLREDTVPALTPAAVPLTKLTPATLRTGR
                     LPADAVRGDYLYAGLGLFKELRQDLQSPFGACSVELPPRWGRREPAIGRAADYATSRTV
                     AVLEGLERYAGLHRGGTLPPVRARYADVADQALYPPDLGTHPEESYASEGFRYRPFDPG
                     TEIDWVGAYSFRRDGRVLVPERAAFWGPRHDDEISFFYDTSNGCALGNSVEEAVLHGLR
                     ELAERDAFLLTWYRELDVPEVALDGTSPALDHLLAKSRLFTGFDFRCFDATMEYGVPAL
                     LLTAENDSGDGPRLFAGCGAHPDPVQAVTGALHELVGTVLATRDAYERRRPDALRMLAD
                     PFLIRRMEDHSTVGALPEARDRFSFLLDRPRTGAPVPLGRVRSTLRTQDADLRADLYAA
                     VSGVLDCGLDVLVVDQTMPELRRNGLHCVRVLVPGLIPMTFGHRNRRTCGLPRLTEGTT
                     LPYRSLLAPGREIGAVPHPFP"
     gene            complement(12797..14761)
                     /gene="nosH"
     CDS             complement(12797..14761)
                     /codon_start=1
                     /gene="nosH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_kind="biosynthetic-additional"
                     /note="hypothetical protein"
                     /product="NosH"
                     /protein_id="ACR48337.1"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 3.6e-30,
                     bitscore: 94.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     2.8e-13, bitscore: 40.4, seeds: 5, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVAADRAQPAGPAADPLTDTLTRTYRLRADAFYVRQQDGVWLG
                     NNTGSFSVRGQGAYQLVSSLFAGLDGERTLQDLYGDLPDRARRSVLGLVRAMLRNGFIK
                     EVAHPVEPVPGWMRERYATHLAFLEHHADRPVTRLQQVRTARVVCAGRGTALHALLDAL
                     REFGIARLDVVPDGDDDLTAVQQVLKETAAADPGARWRLRDPLAADGPAALAGHPDVEG
                     ADAVLLAYDSADAAALARSQHALWRDGVTVGVLARCGDFVTALEPGLGTPYCWECVHRS
                     IAVRATGDTAGLAPAVAPAAVGALRVAQHTFARLAGVRPPGDKPVTTVEPLVPAVRGHA
                     ARRHPRCPHHEPAVPRRLPPAGAAAPEDAVRPDIPRSEDPPERVRISDRIVAACAALTD
                     AVTGPLLALGEEDLAQLPLSASACQVADPDGGADAPAALGVVCRALSPREARNQVVLCA
                     VESLAGRLTAGDARYGAVGAGWSLGEARLRARLHAALGRPTPDLHWAPAPEEPPPGDTA
                     AGYLAGVLAAEGTPWTATAAEELPDGVVRAHVRTRDGAVTAGVGTDRERAVGHALLNAV
                     ARVLPLPGNAQEATAFLAPATATWTAAPTAEGEREITDLLPFLTDTDTGTGTGTGTGSG
                     GEAGARVRVVALPVSEEAS"
     gene            complement(14763..16097)
                     /gene="nosI"
     CDS             complement(14763..16097)
                     /NRPS_PKS="Domain: AMP-binding (116-356). E-value: 1.9e-26.
                     Score: 84.4. Matches aSDomain:
                     nrpspksdomains_nosI_AMP-binding.1"
                     /codon_start=1
                     /gene="nosI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     110.1; E-value: 1.6e-33)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative acyl-CoA synthetase"
                     /product="NosI"
                     /protein_id="ACR48338.1"
                     /sec_met_domain="AMP-binding (E-value: 4.7e-27, bitscore:
                     85.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDMGRPAFQRFLTPRHLPAGRAGAVTGVRWGGDFAAWDDLLTAG
                     RDLAAQVRPGGAYAIDPTAGLPALAALFAVATVPDTVLLWASPRTLGVTGREIAPALHA
                     LPDDGSVPLAAQERPLWGVCTSGSSGAPKVAVGPADEWEQIALHAEAAMYADAFPAGPP
                     EALATCLPLGFSAAFFMCVLPALYLKRDLVVHPPHDWSPLYDLARDRRVLALGVPALAA
                     AACLSAPAATDLGSVALFLGGGHLSAPRVELIRRHFTGAAVSNLYGTAETGAIALDHDP
                     GHNRHVGRPIPGKSVWLTGTDERGIGTVAVAGPGCCRRTWRPGSPPSAPADHVTGTDYG
                     RFDADGNLCLEGRLDGAEKLAGVLVRPREIERHVLALDGVSDVRVTVETAPTGLEFLAA
                     TVVGSVDADTVRAHCAALPEQHRPSRISCASEQEAATVYSAHGKL"
     aSDomain        complement(15030..15749)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nosI_AMP-binding.1"
                     /evalue="1.90E-26"
                     /label="nosI_AMP-binding.1"
                     /locus_tag="nosI"
                     /protein_end="356"
                     /protein_start="116"
                     /score="84.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ERPLWGVCTSGSSGAPKVAVGPADEWEQIALHAEAAMYADAFPAG
                     PPEALATCLPLGFSAAFFMCVLPALYLKRDLVVHPPHDWSPLYDLARDRRVLALGVPAL
                     AAAACLSAPAATDLGSVALFLGGGHLSAPRVELIRRHFTGAAVSNLYGTAETGAIALDH
                     DPGHNRHVGRPIPGKSVWLTGTDERGIGTVAVAGPGCCRRTWRPGSPPSAPADHVTGTD
                     YGRFDADGNLCLEGRLDG"
     gene            complement(16058..16297)
                     /gene="nosJ"
     CDS             complement(16058..16297)
                     /codon_start=1
                     /gene="nosJ"
                     /note="putative ATP-dependent Clp protease"
                     /product="NosJ"
                     /protein_id="ACR48339.1"
                     /transl_table=11
                     /translation="MTSQRTTPRTPDGVPDLQEELAGLLQEDDPRRRLDSLETVVVLSY
                     FARQAPGRTLPELPDAPRTIEGWVTWADQRSSAS"
     gene            complement(16294..17106)
                     /gene="nosK"
     CDS             complement(16294..17106)
                     /codon_start=1
                     /gene="nosK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036:alpha/beta hydrolase fold protein (Score: 38.7;
                     E-value: 1.6e-11)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative hydrolase"
                     /product="NosK"
                     /protein_id="ACR48340.1"
                     /sec_met_domain="PF00561 (E-value: 2.5e-10, bitscore: 31.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.6e-16, bitscore:
                     52.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAETPMDTETPRDTETPMHTGMSTGPETPTVYLVHGLLGTGHGH
                     FAAQIRAWHGRLRTVPVDLPGHGRCRRDAAEDYFDDALRYLVAVLERFGPGRLIGASYL
                     GGPLAHRCAATRPDLVSSLVLTGFAPDVSRDAFLSLIAGFEGLAAQQPALAAEYEQLHG
                     TRWKRTLDAVTGHVERDFERTALVRAADVAALTVPTLVLNGSLKSVERAAAEQAPGWGG
                     RVRGRVVPGAGHLVGHDRPREFNEAVEDFWRTAHDAPAGPRTTQKGDT"
     gene            complement(17114..18316)
                     /gene="nosL"
     CDS             complement(17114..18316)
                     /codon_start=1
                     /gene="nosL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: PF06968"
                     /gene_kind="biosynthetic"
                     /note="radical SAM:biotin and thiamin synthesis-associated
                     protein"
                     /product="NosL"
                     /protein_id="ACR48341.1"
                     /sec_met_domain="PF06968 (E-value: 6.5e-09, bitscore: 26.7,
                     seeds: 824, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQNSQAMTSHAMTGDFVLPELEDVRAEAATVDTRAVLALAEGEE
                     PAESRAAVALALWEDRSIGTAELQAAAEARCGARRPRLHTFVPLYTTNYCDSECKMCSM
                     RKGNHRLDRKFSGRKEITEQLEILYHHEGVRGVGFLTGEYEDKHTRLASAFRIGWAIRT
                     ALDLGFERVYFNIGSMEQDEIDVLGEWIGREDPVTMCVFQESYDRETYRRFMGKTSVGV
                     PKADFDRRVVSFDRWLDAGYRYVNPGVLVGLHDDLSAELVSLVAHGDHLRSRGATADLS
                     VPRMRPAMKSRDTTRVGDDDYLRLMSVVAFTCPEQRLVLTTREPQEFQDVALGLAGVIS
                     PGSPDVAPYRAGCEARNDEKSSQFLVADLRRPRHILGRIEASGTPVDHFVNPAGEASRA
                     V"
     gene            18668..18820
                     /gene="nosM"
     CDS             18668..18820
                     /codon_start=1
                     /gene="nosM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: thiostrepton"
                     /gene_functions="biosynthetic-additional (thiopeptides)
                     predicted thiopeptide"
                     /gene_kind="biosynthetic"
                     /note="nosiheptide propeptide"
                     /product="NosM"
                     /protein_id="ACR48342.1"
                     /sec_met_domain="thiostrepton (E-value: 1.5e-15, bitscore:
                     47.9, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAAHLSDLDIDALEISEFLDESRLEDSEVVAKVMSASCTTCECC
                     CSCSS"
     CDS_motif       18668..18778
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MDAAHLSDLDIDALEISEFLDESRLEDSEVVAKVMSA"
                     /locus_tag="nosM_thiopeptide"
                     /aSTool="thiopeptides"
                     /tool="antismash"
     CDS_motif       18779..18820
                     /prepeptide="core"
                     /locus_tag="nosM_thiopeptide"
                     /peptide="thiopeptide"
                     /predicted_class="Type I"
                     /score="10.70"
                     /molecular_weight="1316.5"
                     /monoisotopic_mass="1315.3"
                     /core_sequence="SCTTCECCCSCSS"
                     /aSTool="thiopeptides"
                     /tool="antismash"
                     /leader_sequence="MDAAHLSDLDIDALEISEFLDESRLEDSEVVAKVMSA"
                     /leader_location="[18667:18778](+)"
                     /alternative_weights="1334.5"
                     /alternative_weights="1352.5"
                     /alternative_weights="1370.6"
                     /alternative_weights="1388.6"
                     /alternative_weights="1406.6"
                     /alternative_weights="1424.6"
     gene            18891..20078
                     /gene="nosN"
     CDS             18891..20078
                     /codon_start=1
                     /gene="nosN"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: PF04055"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 69.2; E-value: 4.5e-21)"
                     /gene_kind="biosynthetic"
                     /note="putative methyltransferase"
                     /product="NosN"
                     /protein_id="ACR48343.1"
                     /sec_met_domain="PF04055 (E-value: 6.6e-19, bitscore: 59.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQNLLMIYVHIPFCHSKCTFCDWVQAIPTKDLLRKPGDSVRQKY
                     ISALCAEIAERGAMHRAAGDIPHVLYWGGGTASSLDEQETAAVMEALHSSFDMSTVAEA
                     TIECSPDTVDERKLAFYRGLGFNRVSSGVQSFDDDRLRRLGRRHTAEQAGRIVHAARAA
                     GFEDVSIDIMSGFPDQEADELDRTVDRALELPVNHLSLYSFRPTPGTFMRRRMDSSERR
                     TYLRRQQALFTRARRAIEGFGLSEYANGYFGKVSPFASMYFQHRADTVGLGSGAISLVD
                     QRFKSHQKGLLHSYVDDPLAFDIDVPAGQDRVLVSLLQAGLAMFDGIPREDWRQRTGTD
                     LAEVLLRPTVAPLADFLRGRGLVEDDHGIRLPRDIAGLTLIELAFEMAMSQPELV"
     gene            20075..21187
                     /gene="nosO"
     CDS             20075..21187
                     /codon_start=1
                     /gene="nosO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /note="hypothetical protein"
                     /product="NosO"
                     /protein_id="ACR48344.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 8.5e-12, bitscore:
                     35.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSGPGQAPAEAAHAAGAAWLEIGLDAPADAVPALVAGVVRPLLR
                     EPAEPGAEPVPGFFLRGVGAAQPALVVQLEVTPGTDLAEPYAARARALAAGLGLPVQVA
                     AGRATLVPLAGSVFAGAALGPVTRAALAAVCPALLTATEAAEQGRPALLASAAELMSAH
                     LRAVSVSAAPGPRQWEELREGVPLGFLSYRSHAEAFLASSRDPKAAQAMMDAKYTRAAA
                     TLERLVDGVLTQCEERGPVVSLPARQWYEAMRAAKPAVTELFRAGTDLALDTEEQPPDT
                     GPDGKGLSESAFHRIVEGSDGLRDFLDRDPSFLATRLLTSLLYLSLSSVGIALAERYFL
                     CYAVSRACESIFDTDALTVLSGLARTSLAS"
     gene            21497..22468
                     /gene="nosP"
     CDS             21497..22468
                     /codon_start=1
                     /gene="nosP"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1041:transcriptional regulator, SARP family (Score:
                     315.3; E-value: 1.7e-95)"
                     /gene_kind="regulatory"
                     /note="SARP family pathway specific regulatory protein"
                     /product="NosP"
                     /protein_id="ACR48345.1"
                     /transl_table=11
                     /translation="MIPAGRRTARSSRAHAAPCRVCRFPHVASTHREMRCRQHGRSTCA
                     PPQRGSSMEIDVLGPLEVSQKSASIVPTASKPRTVLAMLAVYTNRLVPLPSLMGELWGP
                     EPPATAKTAVQGYILHLRKRIAESAARRPPGQFPEAKDILVTLPGGYLLRAPGTAVVLE
                     QFEQLACAGHRAREKGDFEAASRSFTEALGLWRGRALADVEVGPQLGIEVQRIEEARLN
                     VLDRRIEADLRLGRHHELLGELRSVTAHHPTHEGFCAHLMLALYRSGRRCEALDAYQRM
                     RTTLVNELGLEPSPSLRRLQRSLLVSDRELDELNVTWDVATF"
     gene            complement(22542..26441)
                     /gene="nos4"
     CDS             complement(22542..26441)
                     /codon_start=1
                     /gene="nos4"
                     /note="DNA-directed RNA polymerase subunit beta'"
                     /product="Nos4"
                     /protein_id="ACR48346.1"
                     /transl_table=11
                     /translation="MLDVNFFDELRIGLATADDIRQWSHGEVKKPETINYRTLKPEKDG
                     LFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHI
                     WYFKGVPSRLGYLLDLAPKDLEKVIYFAAYMITYVDEERRTRDLPSLEAHVSVERQQIE
                     NRRDADLEARAKKLEADLAELEAEGAKADVRRKVREGAEREMKQLRDRAQREIDRLDEV
                     WTRFKNLKVQDLEGDELLYRELRDRFGTYFDGSMGAAALQKRLESFDLEEEAEKLREII
                     RTGKGQKKTRALKRLKVVSAFLQTSNSPKGMVLDCVPVIPPDLRPMVQLDGGRFATSDL
                     NDLYRRVINRNNRLKRLLDLGAPEIIVNNEKRMLQEAVDALFDNGRRGRPVTGPGNRPL
                     KSLSDMLKGKQGRFRQNLLGKRVDYSARSVIVVGPQLKLHQCGLPKAMALELFKPFVMK
                     RLVDLNHAQNIKSAKRMVERGRTVVYDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPQLV
                     EGKAIQIHPLVCTAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILKPADGRPVTM
                     PTQDMVLGLFFLTTDAEGRGVKGEDRAFASVAEAIMAFDAGELSLQAPVHIRFPVGTIP
                     PRGWVPPVREEGEPEWQQGDSFTLKTTLGRALFNELLPEDYPFVDYEVGKKQLSEIVND
                     LAERYPKVIVAATLDNLKASGFYWATRSGVTVAISDVVVPEAKKEIVKGYEAQDEKVQK
                     QYERGLITKDERTQELIAIWTKATNEVAEAMNDNFPKTNPIFMMVNSGARGNMMQMRQI
                     AGMRGLVSNAKNETIPRPIKASFREGLSVLEYFISTHGARKGLADTALRTADSGYLTRR
                     LVDVSQDVIIREEDCGTDRGLKLKIAERGADGVLRKADDVETSVYARCLAEDIVVDGQV
                     LAPAGTDLGDVLIEELVQRGVEEVKTRSVLTCESAVGTCAMCYGRSLATGKLVDIGEAV
                     GIIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVVELFEARTPKGVAPISEASGRV
                     RIEETEKTKKIVITPDDGSDETAYPISKRARLLVSEGEHVEVGQKLTVGATNPHDVLRI
                     LGQRAVQVHLVGEVQKVYNSQGVSIHDKHIEIIIRQMLRRVTIIESGDAELLPGELVER
                     SKFEHENRRVVQEGGHPASGRPQLMGITKASLATESWLSAASFQETTRVLTDAAINAKS
                     DSLIGLKENVIIGKLIPAGTGLSRYRNIRVEPTEEAKAAMYSAVGYDDIDYSPFGTGSG
                     QAVPLEDYDYGPYNQ"
     gene            complement(26549..30094)
                     /gene="nos5"
     CDS             complement(26549..30094)
                     /codon_start=1
                     /gene="nos5"
                     /note="DNA-directed RNA polymerase subunit beta"
                     /product="Nos5"
                     /protein_id="ACR48347.1"
                     /transl_table=11
                     /translation="MYGGGAGTRVVSPSPRKDPLLAASRTASTANTNNGASTAPLRISF
                     AKIKEPLEVPNLLALQTESFDWLLGNTAWQSRVEEALENGQDVPTKSGLEEIFEEISPI
                     EDFSGSMSLTFRDHRFEPPKNSIDECKERDFTYAAPLFVTAEFTNNETGEIKSQTVFMG
                     DFPLMTNKGTFVINGTERVVVSQLVRSPGVYFDSSIDKTSDKDIFSAKIIPSRGAWLEM
                     EIDKRDMVGVRIDRKRKQSVTVLLKALGWTTEQILEEFGEYESMRATLEKDHTQGQDDA
                     LLDIYRKLRPGEPPTREAAQTLLENLYFNPKRYDLAKVGRYKVNKKLGTDTPLDAGILT
                     VEDIIATIKYLVKLHAGETETVGDNGQPVVVETDDIDHFGNRRLRSVGELIQNQVRTGL
                     ARMERVVRERMTTQDVEAITPQTLINIRPVVASIKEFFGTSQLSQFMDQNNPLSGLTHK
                     RRLSALGPGGLSRERAGFEVRDVHPSHYGRMCPIETPEGPNIGLIGSLATYGRVNAFGF
                     VETPYRKVVDGQVTDEVNYLTADEEDRFVIAQANAPLTADMRFEEARVLVRRRGGEVDY
                     VAPEDVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMMRQAVPLIKSEAPLVGTG
                     MEYRSAVDAGDVVKAEKDGVVQEVSADYITTANDDGTYITYRLAKFSRSNQGTSVNQKV
                     IVNEGDRVITGQVLADGPATQNGEMALGKNLLVAFMPWEGHNYEDAIILSQRLVQDDVL
                     SSIHIEEHEVDARDTKLGPEEITRDIPNVSEEVLADLDERGIIRIGAEVIAGDILVGKV
                     TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGETGKVIGVRVFDREEGDELPPGV
                     NQLVRVYVAQKRKITDGDKLAGRHGNKGVISKILPIEDMPFLEDGTPVDIILNPLGVPS
                     RMNPGQVLEIHLGWLASRGWDVSGLADEWAQRLQAIGADKVEPGTNVATPVFDGAREDE
                     LAGLLQHTIPNRDGERMVLPSGKARLFDGRSGEPFPDPISVGYMYILKLHHLVDDKLHA
                     RSTGPYSMITQQPLGGKAQFGGQRFGEMEVWALEAYGAAYALQELLTIKSDDVTGRVKV
                     YEAIVKGENIPEPGIPESFKVLIKEMQSLCLNVEVLSSDGMSIEMRDTDEDVFRAAEEL
                     GIDLSRREPSSVEEV"
     gene            complement(30573..30962)
                     /gene="nos6"
     CDS             complement(30573..30962)
                     /codon_start=1
                     /gene="nos6"
                     /note="50S ribosomal protein L7/L12"
                     /product="Nos6"
                     /protein_id="ACR48348.1"
                     /transl_table=11
                     /translation="MAKLTQDELLAQFEEMTLIELSEFVKAFEEKFDVTAAAAAPVVVA
                     GGAAGGAAAEAEEEKDEFDVILTGAGDKKIQVIKVVRELTSLGLKEAKDLVDGTPKPVL
                     EKVNKEQADKAAEALKGAGASVEVK"
     gene            complement(31080..31610)
                     /gene="nos7"
     CDS             complement(31080..31610)
                     /codon_start=1
                     /gene="nos7"
                     /note="50S ribosomal protein L10"
                     /product="Nos7"
                     /protein_id="ACR48349.1"
                     /transl_table=11
                     /translation="MARPDKAAAVAELTDKFRNSSAAVLTEYRGLTVAQTRKLRLALGE
                     NAQYAVVKNTLTKIAANEAGITTLDDLFNGPTAVAFVTGDPVESAKGLRDFAKENPNLV
                     IKGGVLDGKALSADEIKKLADLESREVLLSKLAGAFKAKQSQAASVFQALPSKLVRTVD
                     ALRAKQAEQGGAE"
     gene            complement(31902..32720)
                     /gene="nos8"
     CDS             complement(31902..32720)
                     /codon_start=1
                     /gene="nos8"
                     /note="lipoprotein"
                     /product="Nos8"
                     /protein_id="ACR48350.1"
                     /transl_table=11
                     /translation="MKRAVSTAALAGLLLAGAVGCGKGEQSPDLEPAAAVARAAKNADA
                     VTSFRYRLDGRVPGEGRVRGEAAMSTKPPALSMKITPEDQADAGQVEIRFVDKAMYING
                     GAEAAGEMDGKSWIKFDMSKAGKEANPLAGAGATAEQNPAAQSTFLAGADDVREVGAET
                     VDGVKTTHYQGTATLDALEKSLKGTDKASRDKRQKSLDEFEKLGIDKLSMDLWVDGEDH
                     TKRFRMRGDADKGPLDMTITFYDVNKPVTVTAPPAKDVADLAEMMKGVQG"
     gene            complement(32807..33700)
                     /gene="nos9"
     CDS             complement(32807..33700)
                     /codon_start=1
                     /gene="nos9"
                     /note="lipoprotein"
                     /product="Nos9"
                     /protein_id="ACR48351.1"
                     /transl_table=11
                     /translation="MRHRGTARPRGAAPTTTALLAAVAALTALTGCGGSDDGAARPDAT
                     GGTVSAAPRPDPRTADALRAVERAVAGAGSARISSTTAMGDLLSTRTEGALDWAGDSTG
                     TLRITYTGGSLTEPLRKLGTTTMEARLLPDAYYARVGEDFARRMGGRHWIRYDFDDLAE
                     LPGDSGAYLRDQLRDTAPVLPVRLLLASGTVRETGRETVGGRATRHYTGTVDVSALGDV
                     ALRRQLTDAGVTAEQVDIWVDEKNLLVKKVEKAEMTSGPMTQTAYYDTYGVRVAVQRPP
                     DGDTEDFEALMGGQGS"
     gene            complement(33821..34546)
                     /gene="nos10"
     CDS             complement(33821..34546)
                     /codon_start=1
                     /gene="nos10"
                     /note="50S ribosomal protein L1"
                     /product="Nos10"
                     /protein_id="ACR48352.1"
                     /transl_table=11
                     /translation="MSKRSKALKAADAKVDREKLYAPLEAVRLAKETSTTKFDATVEVA
                     FRLGVDPRKADQMVRGTVNLPHGTGKTARVLVFATGDRAEAARAAGADIVGADELIDEV
                     SKGRLDFDAVVATPDLMGKVGRLGRVLGPRGLMPNPKTGTVTPDVTKAVTDIKGGKIEF
                     RVDKHSNLHFIIGKASFDDAKLVENYGAALEEILRLKPSAAKGRYIKKAAITTTMGPGI
                     PVDPNRTRNLLVEEDPAAV"
ORIGIN
        1 cgccagcgcc gcgaggggct cctcgtcgga cggcttgcgc ttgatgacct cttcggcgtt
       61 gtcgaccgcg tggccctcga tggcctcgat gtcgaccggg gagggcaggt agcgcacgac
      121 cgcgtcgagc aggggctgga cgcccttgtt cttgaacgcg gtgccgcaga agaccggggt
      181 caccgtggtg ccctggccct tgccggaagc gatcgtgata cggcggatgg ccgcgtacag
      241 ctgctcctcg gagggctcct cgccctccag gtacagctcc atgatctctt cgtcgttctc
      301 ggcgacggcc tcgagcagct tgccgcgcca ctcctcggcg gcctcggtgt gcgtggccgg
      361 gatgtcgacg acgtcgtaca tctcgccctt ggtcgcctcg gcggaccaca cgagcgcctt
      421 catgcggacc aggtccacga cgcccttgaa gtcggcctca gcgccgatcg gcagctgcat
      481 cacgatcggc tgggcaccca gccggtcgct gatcatgtcg acacagcggt ggaactcggc
      541 accggtgcgg tcgagcttgt tgacgaagca gatacgcgga acgccgtagc ggtccgcctg
      601 acgccacacc gtctcggact gcggctcgac gccggcgacg ccgtcgaaca ccgtcacggc
      661 accgtcgagc acgcgcaggg aacgctccac ctcgacggtg aagtcgacgt gacccggcgt
      721 gtcgatgatg ttgatggtgt ggtcgacgtc gtccagcgac cagtgacagg tggtggcagc
      781 agaggtgatc gtgatgccac gctcctgctc ctgctccatc cagtccatgg tggcagcgcc
      841 gtcgtggacc tcaccgatct tgtaggacac accggtgtag aacaggatcc gctcggtggt
      901 ggtcgtcttg cccgcgtcga tgtgggccat gatgccgatg ttgcgcacct tggccaggtc
      961 aagcgaagtg gtagccataa ggcttcagtc ttctctcggt tctcgaaggg gttccgacta
     1021 ccagcggtag tgcgcgaagg ccttgttgga ctcggccatc ttgtgcgtgt cctcgcgctt
     1081 cttcaccgcg gcgccgaggc cgttggaggc gtcgaggagc tcgttgagca gacgctcggt
     1141 catggtcttc tcgcgacggg cgcgggagta accgacgagc cagcgcagcg ccagggtgtt
     1201 ggcacggccg ggcttgacct cgaccgggac ctggtaggtg gcgccaccga cacggcggga
     1261 cttgacctcg agggtcggct tgatgttctc gagagcgcgc ttgagcgtga tgaccgggtc
     1321 gttgccggtc ttctcgcgca ggccctccat ggcgccgtag acgatgcgct cggcggtgga
     1381 gcgcttgccg ttcagcagca ccttgttgat cagggaggtc accagaggag aaccgtagac
     1441 cgggtcgatg atgaccgggc gcttcggggc ggggccctta cgaggcattc ttacttctcc
     1501 ttcttggcgc cgtagcggct gcgggcctgc ttgcggttct tgacaccctg ggtgtcgagc
     1561 gagccacgga tgatcttgta gcgaacaccc ggcaggtcct tcacacggcc gccgcgcacg
     1621 agcacgatgg agtgctcctg caggttgtgt ccctcacccg gaatgtaagc ggtgacctcg
     1681 atcccgctgg tcagacgcac acgcgcgacc ttacgcaggg ccgagttcgg cttcttcggg
     1741 gtggtcgtga acacacgcgt gcagacgcca cgacgctgag gggaaccctc gagtgcgggc
     1801 gtcttgttct tctcgacctt gtcctgccgg cccttgcgga ccagctgctg gatcgtaggc
     1861 actacttctc cggtttctgt gtgccgaatg gtgaagctaa cctggaacgt cgccgaccca
     1921 cgcggtcggg tgtgtcgaat cgtgcggact cccgccgcaa ggcagaaaga ggcgcagatt
     1981 gcggtggccg gtgacggctc tctgtgcggt tgaaggcacg cacgagagcc agggcacacc
     2041 ccaggcacaa ggtctgagcg tacctagccc gtcagctccg gtcaaaacaa atggaacccg
     2101 ccccggtgga ccggggccgc gagcgcaccg cgtaccgatt catcccggta cgtacggtac
     2161 ccgggcatgg ccggagcatg cccgggtacc ggggggcgcg cgaggggcgc gcggaaggcg
     2221 ctgatttttg gtggtgtctc cgctcgcgct acgccggcgg ccgggagggg atgaaggcgt
     2281 cggcgcccgg cggtacgaac tcctgcgggc gggtcagcgg ctcgggcgag gccgggtcga
     2341 aggccaggcc cagccccttg ccgaagggtg cggcggcagc ggcggggccc tcggtggcgg
     2401 cctcgacgct gtagtagcgg cgctcggtcg ggcggtagcc gatcagctcc acgaccttgg
     2461 acacgccggg cgggcggccg taggcggcct cgggcgagtc ccagaggtag accgcgcccc
     2521 actgctcgcc ctcggggccg gtggaggaga tccacgtctt ctgccgcagg ccgggcacgg
     2581 tcgtgtacgc gtccacggcg tggtcgcgca ggtaggcgcg cagggaggcg acggtcgccg
     2641 cggagcggga caggtcccac aggacgaccg tgcagtacag ctgctgtgcg gggtgttcgg
     2701 tcatcgcagg accgccttca gttcgcgcgg gtaccggtgg aagaggttcg cggtgaactc
     2761 cacggcggcc gggtcggcgg ccggggtgag ggcggggaag cggcgcagca gccggccgaa
     2821 gccctcctgg agttccacgc gggcgaggga cgagccgagg cagtagtgcg cgccggcgcc
     2881 gaaggtgagg tgggtgcgcg cggcgccccg ggccaggtcg aaggtgtcgg ggcggtcgac
     2941 gtgccgctcg tcgcgggcgg cggagtcgag ggagatgaag accgtggcgc cctcggggag
     3001 ggtgatgccg ccgagggtca cctcctcggt ggtgacggtc gtcccggcga agccggtgcc
     3061 ggcctgggcg taccgcagga tctcctcgac ggcggcggcc tcggtgacgg tgccgtcgcg
     3121 cagccgggcg agctggtcgg ggtgctggaa gagggcgagg agtccgttgg cgaactggac
     3181 ggcggtggac tcgtagccgg cggtggccag caggacgacg gtggagacga gttcgtcggc
     3241 ggaggggcgg gcgtcctcgt cgaggcccgc gatcaggctg ccgatcagcc cgtcgccggg
     3301 agcggccagc tccttctcca ccagctgccg ggccacgccg aacagcgcgc ccatggccgc
     3361 gccgaaggcg gcggtcgacg gggcggcggc ccgcacctgg gccgcccacc cccacagccc
     3421 ggggcgcagc tcttcgggca ggtcgaacag ctcgcacagc acgcggacgg gcacctggta
     3481 ggcgaagccg gagaccaggt cgacggggtc cggccccgcc tcggcgagcc cgtccagcac
     3541 ctcgtccacc gcctgcccga ccgccttgcg cagcgactcg gcgtgccggg gggtgaggac
     3601 ggtggcgagg gtacggcgcc accgggcgtg ccgctcgggg tcggccagcg ccatcccgaa
     3661 gtcgaaccgc tgcccgggcc ccttaccggg ggcacccggg cccacactgg ctccgcccgg
     3721 gccgccaggc ccgggcaccc cacccggcca accaccctgc ggtgcacccc cggcggagcc
     3781 gccggggccg cccggccaac cgccctgcgg ggcaccctcg gcggagccgc ccgggccgcc
     3841 cgggccgggc gggccgcccc ggagggctcc cgctcggatc gccgcgcggc tgaagcgggg
     3901 gtcggtcagg accgtgcgga cgtcgtcgtg gcgggtgacc agccaggccg tggcgccgtt
     3961 cgcgaggcgg atctgtgaga cgggggcctc gtcgcggcgg cggaccagtt catcgggtgg
     4021 ggcgaagggg cacttctgct cgaaggggta cgtcgggctc tcgtccatgg gggcctccac
     4081 gctcagatcc gcaccggcag ctcggccgga tagaaggtga acaggttgct ggcgagcggc
     4141 acgccgtcca ggtcgggccc gtcgaaccgc aggtccggga agcggttcag catgcgcgcg
     4201 atgccctcct gcatctcgac gcgggccagc gcggcgccca ggcagtagtg ggggccgtag
     4261 ccgaacgcgg tctgccggtg ggcgcagccg cggccgacgt cgaagcggtc ggcgtcctcg
     4321 ccgaagacct tctcgtcccg gttggccgac gcgagggaga cgaagacggt cgagccggcc
     4381 gggacggtcc cgccggacag ctcgacgtcc tcggtggtga acttggcgat ggcgtacccg
     4441 gtgcccatct gggcgtaccg caggatctcc tcgacggcct ggccgatcag cgcgggctcc
     4501 tcgcgcagcc ggcgcatctg ggaggggtcg cggaacaggg cgtagaaggc gttgccgagc
     4561 tggacggcgg tgctctcgta gccggccatc agcagcagga tgaccgtgga gaccagttcc
     4621 tcgttgctga gccggccgtc ctcctcgtcg gtgaggccga tcagcgtgct gagcaggtcg
     4681 tcgcccaggt tctgccgctt gcggacgatc agcccgatgg cgtaccggcc gatcgcctgg
     4741 agggcctggc cgaactcgac gaacgacgag gtgaagtcgc ggcgggtgat ctgcgcggcg
     4801 agcgcggaga actcggggcg ggcggtctgc tccagtccga gcaggtcgca gatgacccgg
     4861 atcggcagct ggtaggcgta gtcggccatg aggtcgaagc gaccgccggc gctttcgagg
     4921 tcgtcgagga gggcgtcggt gtgggcggcg acggcgggcc gcatcgactc ggcgtggcgg
     4981 gcggtgaacg cctggttgac caggcggcgc cagcgggtgt ggccgggcgg ttcggagatg
     5041 gagccgccga agttgaagac ggggctgtcg gcgtcggcct ggaagccggt gtccacccgg
     5101 gccgcgccct cccggttgat ggtgcgggag aaccgcgggt cggtgagggc ggtgcggacg
     5161 tcctcgtagc gggtgatcag ccaggcggtg tcgccggtgg cgaggcggac ctgggcgatg
     5221 ggccggttct cgcgcagcca ggcgaactcc tccggcatct cgaacggggt gtggcgggtg
     5281 aaggggtagg tgcgcgcttc gatgtccacg gcaggggctc ctgtcggtca gtgctggccg
     5341 gagggcagat gggcggcgag gcgttcccgg cggtggtcgc ggacccggtc gagcaggccg
     5401 gcgtccgggg cgaggcccgc gcagtcggcg acgacgtggt ggccgaggta gccgaggaag
     5461 gcctcctgct ccgggatgag gcccagccgg ttgttgtggg tgtgcagata gctgaggagc
     5521 acgatctggc ggcgccgctc cgccggcgcg tcggggccgc cgagcgtgac cgcgggcagc
     5581 acggtgtccg cggccgtgtg cagcgcctgc caggcctcgc cgacggcccg gccgtagggg
     5641 tcgtcgggcg gctgcgcggc ggcgagcagc ggccgcaggt gggcggcggc cgggccgcgg
     5701 cgctggtcca gcagctcggg ccaggtgtcg aggaagctgt cgaagacgta cggcgaccac
     5761 accgcgcagt agtgggcgag gaacccggcc atggcgggcg gcgagagccg ggccgcgcac
     5821 aggccgcgca gcgtcatggt gaacgcggcg cccagccggc gggccgggcg gtcgccgatg
     5881 gcgcgcagcg cggacagggc gacggcgctg ctgcggtcga agaaccgctc ggcgacggcg
     5941 acaccctccg ggccgccgta cttgccgtac tcgggctcgt agcgggcggg gtgcacggtg
     6001 tccggcggga gcagttcgcc ggtcgcctcc gactccagtg cggccatggt cagctgggcc
     6061 tcgcggaact cctcggggtc gaggtctccg tagccgccgg gatgggcggc gaggtggccg
     6121 gcgaggcggt cggcgacctc gcgcacggtg cgggcggcct gctcggggtc gtgggcggcg
     6181 gggcgcaggc ggagccggat gtggtggccg ccctgccagt accgcaggaa gaaggagctc
     6241 tccagcgcgc cggaggcgtg cagcggggcg agcacggggg ccagcccgtc cacgaggaac
     6301 gcgtcctgcc cggcgtaccg gtgcaggtgc aggctgtgcc aggggccggt ctcaggggcg
     6361 ggcatgggcg tcctccgtgg cctgggttcc ggcgggggcg ggggtgccga gggtgtactc
     6421 gacgaagaac tcctccgcgc cggaggtccg gccgtccagg tcgccggcgt gcggcaggca
     6481 ctcctggaag gtgacggtgg cgtccgggcc ggcctcggcg agccggcggg cgaagacctg
     6541 gaggaggaag gggttgcggg cgtcgaggta gtgcggtttg tgcagccggg cggtgcgcgc
     6601 ctccagcgcc cactgccggg tctccgccag caggtcgcgc tcgccggcgg gcacgggcgg
     6661 gggcgtggtc agccggaaga aggtgtgccg ggggatgccg cgctgcccga gccagcggtc
     6721 gaacgaggcg agggccgccg cctcctgccg ttccaggccg tcggtgtccg ggacgtccgc
     6781 cgcgggcagc cgccaggagg cccggtcgag gacgaggtcg ccgagcagta cccggggcag
     6841 cgaccggtgg gtggcgggga cgccggtgcg gccggcggcc cggcccgctt ccgcgtcggc
     6901 ccggtcgagc tggtcccaca gtccgccgcg gtaggtgcgg gtgggggcga aggcgcacag
     6961 cagccggtac aggccgggtg cggcggccgg gtagaggaag ttgagcggta cgaggtccag
     7021 gggctgcccg tcgcgggtgc tgaccagggc cagggtgcgg cgggccgggt cggcgcggac
     7081 ggccaggtcg gcgagggtca gggtgtgctc gtcggcggcg cgcggcaccg agccggggta
     7141 gaccagctcg tacgggctga gccgggggtg caggttgaag ttgaggccga ggacggccgt
     7201 gatgtcgcac tggcggggcg tcgtgcgggc gatgtggccg cgcagcgcct cggtgaggct
     7261 ccactcgtgc ggcccgtccg gctccagcag gtcgcagaac cgggagaaga acacgccgtg
     7321 cccggtggtg acgccgttga cgacggcgta cggccgctcg ggttccgcgg tgaactgcat
     7381 ccggtaggcg gtggaccgcc agggggtcac ctcggcgggc agccggtcgg cgaaggcgcg
     7441 cagccgctcg gcgtccaggc gcagcgcgcc ggtgtgtgcg ctgtcatggg cgcgcagttc
     7501 ggtgcggagg aggtcggcga agtcggcgcg cagccggcgg atgcggtcgc tgtgcgggtc
     7561 gccgacgccg gaggccacgg cactggcctc ggcgggcggc agcgcggcga accggcggta
     7621 gaactcgatg aacgggacgt cgccgtcgcc gtccgccgcg ccgaagtgcc gggcgaagaa
     7681 ggcatacagg cccgccttct ccacgctcgc gtcgtccagc accgggacga tccgctggaa
     7741 cagctccagg gcccagcggt tggcgtgcag caggtccggg tgccagctgt gggcgggttc
     7801 gcgggtgccg acgtcctcgt agacgacgga gcgcatggcc tcgggggcgg gggcgcggca
     7861 gccgacggcc tcgacgaaca cggcgacctg ttcgcggatc tcggccagca gcgcggcccg
     7921 ccgccgcacg ggggcggccg ggaaggcgtc ctcggcggcc tggagccgtt cgaagacgac
     7981 ggcgcagcgg ccggcctggt cggtgtcgag ggtgcgcagc cgctgggcga cggcgagcgc
     8041 ggggcgcggg tgctggtcgg ggatgccgag cccgcgttcg cagatcccgg cgcggaccag
     8101 cttgtccagg gcggtcgccg cggcctgcgg ggagagtccg gcggcggcca gcctctcgcg
     8161 cagctcgcgc tcgggcagcc cgccgtcggc gagcagggac cgcagcaggc gcagcaggcc
     8221 ggtgtcgcgg gcggtcacca cctgggcggt gccgtaggcc gcctcggggg cgccgtccgg
     8281 ggcccgccgt acgcacaggg cctgttcctc ccggacgagc agggagtggt tgagccggat
     8341 ccgcatcagc tcgtcggcgc ggtccaggcg gtgcagttcg tacgtcatcc aggacagcag
     8401 tcccgcgctg agccgggcct ggacggggcg ggccggaggg cggtcggccg gtgccgtgcc
     8461 gtcgccggcg ggcgtccagg gggcggcgcc gatctcggtg aaggaggcga acggcgacgg
     8521 cttgagggcg acccggtagg cgaagctggt cagcgtgttc tcggcgcggc gccgcttgct
     8581 gggcttgcgg cgcgcggaga acgggtcggc ggcccactcg gtgacggtcc gccaggtccg
     8641 ctcgtcggat agctggaggc cgcgctggaa gaactccccc gtcgcgatgg ccgccaacgc
     8701 ccttcgaccc gcgtcgagtt cggcggcgag ggccgcttcg gcctccttgt gcagccggtt
     8761 gccctcggcg cggtgccgca gccagtcctc cagcagttcc cggctcgccg ggtcgagcag
     8821 gcgggcggcg tcggggacgc cggggacgcg gtcgttgtgg atgtcgcgcc gcagccgcag
     8881 cagttcgtgg cgccggtcgg cgggcagctc cggcacggcc gcgtgcagcg cgtcctccag
     8941 gcgcccgcgc agctcctccc gccgctgccg ggtctcctcg gcctccgcga gcagcgccca
     9001 ggtgcgcgcc ggggtcagcg cggccagctc ggacgggccg agcgtgccgc ggcggtagag
     9061 gtagtagggg ctgaacccgt cgggcgcgcc ggcagcgtcg ggcgcgccgg gcacccgggt
     9121 cgtgtcgttc accgtggcat caccgcaatc tcccagttcg ggtcggggcg tacggcgccg
     9181 acgcagatct gcgcctgggt cccgccgtcc gtgtccgcgc cgccgtcgag gccgtacgcc
     9241 gtgtcgatcc gggtcacgtc gaacccgagg acggcgtggc cgctgaggcc ctcggcggcc
     9301 gcggccagcg tcaccgcctc gatcgccgcg cccacggcga gctgctgcgc gcggtaggcg
     9361 cgcgggccgc ccgccggccg ccagtcggcc ggggtcaccg ggtggacggt gaaggcggcc
     9421 agctcggcgt tgaaagaggc ggcgaacagc gcctcctgca cccggcgcgc gctgccgggc
     9481 ccggtcccct cccccacggg cagcagcgcg cccagctcgt gcgcgtaccg gtaccagccc
     9541 ggcggcacgc cgcgcacccg gtggacggcg cagtacaggc gggtccgcgc ggcccacccg
     9601 gccggcccgt ccgccccggc tccggccagc gcccgcagcg cctcggccgc ctgccccagc
     9661 acccccgcga gggcctcccc gtcggcctcg gccccggtga acaagcgccc ccgcgagaac
     9721 cgccgcgcgg cggtctcggc ggcgaggaga tcgagggcgc ggggggcggg cagcggcacc
     9781 gggccgaccg gcacggcgtc cccgggcacg gggcggggcg cggcggccga cacggcgtcc
     9841 tcgtgcacgg ggccgggcgc ggcggccggt ccggcgtccc cgggcacggg gccgggcgcg
     9901 gtggccggta cggcgtcctc gggcggccgg gcgggcgcgg cggtgctcgt gtcctcgcgg
     9961 gccgcgcgct ggaaggcggt gaagcggtcg gagcgccgta ccgtccggga gcgctccagc
    10021 agggcggggc ggggcggggc gtcgggtccg ccggtgtccg ccctgtacgg gaggtacggt
    10081 ccgagcgtca ccgccgccca cgcgttctcc tcctccccgt cgaggccgag gcaggcgtgc
    10141 acggcctcgt cgtcgaagac cgtccgcacc tccgcgtgct cccactcggc ccgcgcgagg
    10201 cgggcggcgc ggccgagggc gaccccggcg tcgaccaggc cgaggcgggt cgcgaagtcg
    10261 ccgtacttgt agaagttctt ccagaagcgg ctggtcagga cgagcaccgc cgcgggcgcc
    10321 gcctccgtcg gcaggtgcag cgcggcgcgc agccgggccg ccgcgtcgcc gccggccagc
    10381 acggtcagct cgtgccggta ggggtcgtag tggcagacct gcccggtcgc ggtgagggcg
    10441 gcgtacacct cggtcgggta catcgccccg cccgacggga cgggccggcg caactgcacc
    10501 tcgggcccgt ggtgcggacg cgggtcggcc ggggtggcgg cgatgccgcc ggacgggtcg
    10561 gtgcggatcc ggctgacggc gaagccgccg tgcaggagcc ggtgcagggc cgcgagcggc
    10621 ggcggtccgt cgggccgcag cggcagccgc cgcgctccgc tgtagacctt caccggccag
    10681 ggcccgtcgg cccagtccac ccgccagccg tccgggttgg cggagcgcgg gtcgagccgc
    10741 agcccggtgg tgtaggtgta cgcctcgtcg gtcgtcatgg tcatggtcgt gcgggttctc
    10801 cttgccggct ggccatcgga cggcatgtcc tacgggaagg ggtgcgggac ggcgccgatc
    10861 tcccggccgg gggccagcag gctgcggtag ggcagggtgg tgccctccgt gagccggggc
    10921 aggccgcagg tacggcggtt gcggtggccg aaggtcatcg ggatcaggcc cggcaccagc
    10981 acccggacgc agtgcaggcc gttgcggcgc agctcgggca tggtctggtc gacgaccagg
    11041 acgtcgaggc cgcagtcgag gacgccggag acggccgcgt acaggtcggc ccgcaggtcg
    11101 gcgtcctgcg tgcggagcgt cgagcggacc cggccgagcg ggacgggggc gccggtgcgg
    11161 ggccggtcga ggaggaagga gaagcggtcg cgggcctcgg gcagcgcgcc gaccgtggag
    11221 tggtcctcca tgcggcggat gaggaacggg tcggccagca tgcgcagcgc gtcggggcgg
    11281 cggcgctcgt aggcgtcccg ggtggcgagg accgtgccca ccagctcgtg cagggcgccg
    11341 gtgacggcct ggacggggtc ggggtgcgcg ccgcagcccg cgaagagccg gggcccgtcg
    11401 ccgctgtcgt tctcggcggt gagcagcagc gccgggacgc cgtactccat cgtggcgtcg
    11461 aagcagcgga agtcgaagcc ggtgaagagg cgggacttgg ccagcaggtg gtccagggcg
    11521 ggcgaggtgc cgtcgagggc gacctctggg acgtcgagtt cgcggtacca ggtgagcagg
    11581 aaggcgtccc gctcggcgag ttcgcgcagg ccgtgcagga cggcctcctc gacgctgttg
    11641 ccgagggcgc agccgttcga ggtgtcgtag aagaaggaga tctcgtcgtc gtggcgcggt
    11701 ccccagaacg cggcgcgctc cgggacgagg acgcgtccgt cgcggcggaa ggagtacgcg
    11761 cccacccagt cgatctcggt gccggggtcg aagggccggt accggaagcc ttcggaggcg
    11821 tagctctcct ccgggtgggt gcccaggtcc ggcgggtaca gggcctggtc ggccacgtcc
    11881 gcgtagcggg cccgcacggg gggcagggtg ccgccgcggt gcaggccggc gtagcgctcc
    11941 aggccctcca ggacggcgac ggtgcggctg gtggcgtagt cggcggcgcg gccgatggcg
    12001 ggctcgcggc ggccccagcg cggcggcagc tccaccgagc aggccccgaa ggggctctgc
    12061 aggtcctgcc gcagctcctt gaacaggccg aggccggcgt agaggtagtc gccgcggacg
    12121 gcgtccgcgg gcagccgtcc ggtgcgcagg gtggccgggg tgagcttggt gagcgggacg
    12181 gcggcggggg tcagcgcggg cacggtgtcc tcgcggaggc tgccgcagtt cgggcagccg
    12241 gagtccggca gcagggtctg ctgctcgacc gtgccggcgg cgccgtcgag gacgaggacg
    12301 cggccgtcgg ccgggccggc cgggcccttg caggacgcga gccgggcgcg gacgtactcc
    12361 tcgaccagcc gcagcacgcc gggtccccag atgcggacgt ccgcgccgtg cggccaggac
    12421 tcggcgaggc tgtcgccctc caggccgggc ccgaagggcg agttggcggt ccgggtcacc
    12481 aggcagcgcg ggcagccctg ggtgccgggg cgccagacgg ggccgatgta gacgagcgag
    12541 cgccagctgc cgacgaagag cagggagcgt ccggtggcca ggcagtcgac gacggtgtcc
    12601 tggaactcgc cgagcccgtc gagcccggcg acgagcacgg tcgccccgga ggaccggccg
    12661 aagcgtgcac cgccgtccgg gtcgggggtg tcgtcgcggc cgaggcgccg gaccagatgc
    12721 tcggcgagca cgccccgccc gacgacgacc ggcggcccgg ccggcccggt gcggggctgc
    12781 ggggtggtcg ccgtactcat gacgcctcct cggacacggg cagggccacg acgcggacgc
    12841 gggcaccggc ctctcccccg ctgccggtgc cggtgccggt gccggtgccg gtgtcggtgt
    12901 cggtgaggaa gggcagcagg tcggtgatct cgcgttcgcc ttcggcggtg ggcgcggcgg
    12961 tccaggtcgc ggtggccggg gccaggaagg cggtggcctc ctgggcgttc ccgggcagcg
    13021 gcaggacgcg cgccaccgcg ttgaggaggg cgtgtcccac cgcccgttcc cggtcggtgc
    13081 ccacgcccgc ggtgaccgcg ccgtcgcggg tgcgcacatg ggcgcggacg acgccgtcgg
    13141 gcagctcctc ggcggcggtg gcggtccagg gcgtgccctc ggcggccagc accccggcga
    13201 ggtagcctgc cgcggtgtcg ccgggcggcg gctcctccgg cgccggagcc cagtggaggt
    13261 ccggcgtggg ccggccgagc gccgcgtgca gccgggcgcg cagccgggcc tcgcccaggg
    13321 accagccggc gccgaccgcg ccgtagcgcg cgtcccctgc ggtgaggcgg ccggccagcg
    13381 actccaccgc gcacagcacg acctggttgc gggcctcgcg cggggacagc gcccggcaca
    13441 ccacgccgag ggcggcgggc gcgtcggcgc cgccgtccgg gtcggcgacc tggcaggcac
    13501 tggccgacag cggcagctgg gccaggtcct cctcgccgag cgcgagcagc gggccggtga
    13561 ccgcgtccgt cagggcggcg caggccgcca cgatccggtc ggagatccgc acccgctcgg
    13621 gcgggtcctc ggagcgcggg atgtcgggcc gcacggcgtc ctcgggtgcg gcggccccgg
    13681 cgggcggcag ccgccgcggt acggcgggct cgtggtgcgg gcagcgcggg tgccgccggg
    13741 cggcgtggcc gcgcaccgcg gggacgaggg gttcgacggt ggtcaccggc ttgtccccgg
    13801 gcggccggac cccggccagc cgggcgaagg tgtgctgcgc gacccgcagc gcgccgaccg
    13861 cggccggggc gaccgccggg gcgaggcccg cggtgtcgcc ggtggcccgg acggcgatcg
    13921 agcggtgcac gcactcccag cagtacgggg tgcccagccc gggttcgagc gcggtgacga
    13981 agtcgccgca ccgggcgagg accccgacgg tcacaccgtc gcgccacagc gcgtgctggg
    14041 agcgggccag cgcggcggcg tcggcgctgt cgtaggcgag caggacggcg tcggcgccct
    14101 cgacgtcggg gtgtccggcc agcgcggccg gtccgtccgc cgcgagcggg tcgcgcagcc
    14161 gccagcgcgc cccgggatcc gccgcggcgg tctccttcag cacctgctgt acggcggtca
    14221 ggtcgtcgtc gccgtccggg accacgtcga gccgggcgat gccgaactcg cgcagcgcgt
    14281 ccagcagggc gtgcagcgcg gtgccgcggc ccgcgcacac cacgcgtgcc gtgcggacct
    14341 gctggaggcg ggtgaccggg cggtcggcgt ggtgttcgag gaacgccaga tgggtggcgt
    14401 accgctcgcg catccagccg ggcaccggct cgacggggtg ggcgacctcc ttgatgaagc
    14461 cgttgcgcag catggcccgc accagcccca gcacggaccg gcgggcccgg tcgggcaggt
    14521 cgccgtagag gtcctggagg gtgcgttcgc cgtccagccc ggcgaagagg gagctgacca
    14581 gctggtaggc gccctggccg cggacggaga aggagccggt gttgttgccg agccagacgc
    14641 cgtcctgctg gcggacgtag aaggcgtcgg cgcggagccg gtaggtgcgg gtgagggtgt
    14701 cggtcagcgg gtcggcggcc gggccggccg gctgtgccct gtctgctgcc acgtctgtca
    14761 tgtcagagct tcccgtgcgc gctgtagacg gttgcggcct cctgctcgga ggcgcagctg
    14821 atccggctgg gccggtgctg ttcggggagg gcggcgcagt gcgcgcggac ggtgtccgcg
    14881 tcgacgctgc cgaccaccgt ggcggccagg aactccaggc cggtcggggc ggtctcgacg
    14941 gtgacccgta cgtcgctgac cccgtcgagc gcgaggacgt ggcgctcgat ctcccggggc
    15001 cgtacgagca ctccggcgag cttctcggcg ccgtcgaggc ggccttcgag gcagaggttg
    15061 ccgtcggcgt cgaagcggcc gtagtcggtg ccggtcacgt ggtcggcggg ggcggagggc
    15121 gggctgccgg gccgccaggt gcgccggcag cagccggggc cggcgacggc gaccgtgccg
    15181 atgccgcgtt cgtcggtgcc ggtcagccac acggacttgc cggggatcgg ccggccgacg
    15241 tgccggttgt ggccggggtc gtggtcgagg gcgatggcgc cggtctcggc ggtgccgtac
    15301 aggttgctga cggcggcgcc ggtgaagtgg cggcggatca gctcgacccg cggggcgctg
    15361 aggtggccgc cgccgaggaa cagggcgacg gagccgaggt cggtggcggc gggcgcggac
    15421 aggcaggccg ccgcggccag ggccgggacg ccgagggcca gcacgcgccg gtcgcgggcg
    15481 aggtcgtaca gcgggctcca gtcgtgcggc gggtgcacga ccaggtcccg tttcaggtag
    15541 agggcgggca ggacgcacat gaagaacgcg gcggagaacc ccagcggcag acaggtggcc
    15601 agcgcctcgg gcgggcccgc ggggaacgcg tccgcgtaca tcgccgcctc ggcgtgcagg
    15661 gcgatctgct cccactcgtc ggcggggccg acggccacct tgggcgcgcc ggagctgccg
    15721 gaggtgcaca cgccccacag cgggcgctcc tgtgccgcga gcggtacgga cccgtcgtcc
    15781 gggagggcgt gcagcgccgg ggcgatctcc cgcccggtga cgccgagggt gcgcggcgac
    15841 gcccagagca ggaccgtgtc cggcacggtg gccacggcga acagcgcggc cagcgcgggg
    15901 agtccggcgg tggggtcgat cgcgtacgcg ccgccgggac gcacctgcgc ggccaggtcg
    15961 cggccggcgg tgagcaggtc gtcccaggcg gcgaagtcgc cgccccagcg gacgccggtc
    16021 acggcaccgg cccggcccgc cgggaggtga cggggggtca ggaagcgctg gaacgctggt
    16081 cggcccatgt cacccacccc tcgatcgtgc gcggcgcgtc gggcagttcg ggcagggtcc
    16141 gcccgggtgc ctgccgggcg aagtacgaca ggacgacgac cgtctccagc gagtcgagcc
    16201 gccgccgcgg gtcgtcctcc tggagcagcc cggccagctc ctcctgcagg tccggtacgc
    16261 cgtccggcgt ccggggtgtg gtgcgctgag atgtcacgtg tcgcccttct gcgtcgttcg
    16321 gggaccggcg ggtgcgtcgt gcgcggtgcg ccagaagtcc tcgaccgcct cgttgaactc
    16381 ccgcggccgg tcgtggccga ccagatggcc ggcgccgggg acgacccggc cgcggacccg
    16441 gccgccccag ccgggcgcct gctcggccgc cgcgcgttcg acggacttca gggagccgtt
    16501 gaggacgagc gtcgggacgg tgagcgcggc cacgtccgcc gcgcggacca gcgcggtccg
    16561 ctcgaagtcc cgctcgacat gcccggtgac cgcgtcgagc gtccgcttcc accgggtgcc
    16621 gtgcagctgc tcgtactcgg cggccagggc cggctgctgc gcggcgaggc cctcgaaacc
    16681 ggcgatcagc gagaggaacg cgtcgcggga gacgtccggc gcgaacccgg tcagcaccag
    16741 cgaggagacc aggtcgggcc gggtggccgc gcagcggtgg gcgagcggcc ctcccaggta
    16801 ggaggcgccg atcagccggc cgggcccgaa gcgttccagc acggcgacga ggtagcgcag
    16861 cgcgtcgtcg aagtagtcct cggcggcgtc acggcggcag cggccgtgac cgggcagatc
    16921 cacgggtacg gtccgcagcc ggccgtgcca ggcccggatc tgcgcggcga agtgcccgtg
    16981 gccggtgccc agcagcccgt gcaccaggta gacggtgggc gtctccgggc ccgtcgacat
    17041 cccggtgtgc atcggcgtct ccgtgtccct cggcgtctcg gtgtccatcg gcgtctccgc
    17101 gtccaccggt gcctcagacc gcccgggacg cctcgcccgc ggggttcacg aagtggtcga
    17161 cgggtgtgcc ggacgcctcg atacggccga ggatgtgccg cggccggcgc aggtcggcga
    17221 cgaggaactg ggaggacttc tcgtcgttgc gggcctcgca gccggcccgg tagggggcga
    17281 cgtcggggct gccgggcgag atcacgccgg ccaggcccag cgcgacgtcc tggaactcct
    17341 gcggctcccg cgtggtgagg acgagccgct gctcgggaca ggtgaaggcg accaccgaca
    17401 tcagccgcag gtagtcgtcg tcgccgaccc gcgtggtgtc ccgggacttc atggccggcc
    17461 gcatccgcgg caccgacagg tcggcggtcg cgccccggga gcgcaggtgg tcgccgtgcg
    17521 cgaccaggct caccagctcg gcggagaggt cgtcgtgcag cccgaccagc accccggggt
    17581 tcacataccg gtagccggcg tccagccagc ggtcgaagga gaccacccgg cggtcgaagt
    17641 cggccttggg caccccgacg gaggtcttgc ccatgaagcg gcggtacgtc tcgcggtcgt
    17701 agctctcctg gaacacgcac atggtgaccg ggtcctcccg gccgatccac tcgccgagga
    17761 cgtcgatctc gtcctgctcc atgctgccga tgttgaagta gacccgctcg aagcccaggt
    17821 ccagggcggt gcggatggcc cagccgatcc ggaaggcgga ggcgagccgg gtgtgcttgt
    17881 cctcgtactc gccggtgagg aagccgaccc cgcggacgcc ctcgtggtgg tagaggatct
    17941 ccagctgctc ggtgatctcc ttgcggccgg agaacttgcg gtcgaggcgg tggttgccct
    18001 tccgcatgga gcacatcttg cactcggagt cgcagtagtt ggtggtgtag agcggcacga
    18061 aggtgtgcag ccgggggcgg cgggccccgc accgggcctc cgcggccgcc tgcagctcgg
    18121 cggtgccgat cgagcggtcc tcccacaggg cgagcgcgac cgccgcccgc gactcggccg
    18181 gctcctcgcc ctcggcgagg gcgaggacgg cacgggtgtc caccgtggcc gcctcggcgc
    18241 gtacgtcctc cagctccggc aggacgaagt caccggtcat tgcgtgcgag gtcattgcct
    18301 gggagttctg cgtcatgtga attcctctgc gaacggccgg aagggacccg gcccatgtaa
    18361 cgccacccgg gaattccgaa caagacaccg aggaaacgga gcactctttc tccgttaccc
    18421 tccccacctg cgcattcacc cagccctgaa ccacctccac ggcggttgtg cagcagaccc
    18481 gaagcgcatg gttagcagcg ctttagcggc ctttttgtgc cgtcacagca gtacagcagc
    18541 ggggaatcag cagaaatgca aaagggccgg aatccttgac tcacggaaga cccgctgcat
    18601 agcctccgag gcacgcgctg caggaaatgc gcgaagtaaa ttaccgtcga catggaaggg
    18661 gtttccggtg gacgctgcac acctgtccga cctggacatc gacgctctcg agatctccga
    18721 gttcctggac gagagccgac tggaggacag cgaggtcgtg gccaaggtca tgtcggcctc
    18781 gtgcaccacc tgcgagtgct gctgttcctg ctcctcctga tggagacggc gccctgtacc
    18841 ggagcgatcc ggtacagggc gccgcttttc tcgacccgaa aggaatccgc atgcggcaga
    18901 acctgctgat gatctatgtg cacatccctt tctgccattc gaagtgcacg ttctgcgact
    18961 gggtccaggc catcccgacg aaggatctcc tgcgcaagcc cggtgactcg gtgcgccaga
    19021 agtacatctc cgcactctgc gcggaaatcg cagagcgggg cgcgatgcat cgcgcggcag
    19081 gtgacatccc ccatgtcctc tactggggcg gcggcacggc cagcagcctc gacgagcagg
    19141 agaccgcggc ggtcatggag gcgctgcact cctccttcga catgagcacg gtggccgagg
    19201 cgaccatcga gtgcagcccg gacaccgtcg acgagcggaa gctggccttc taccgcggtc
    19261 tcggattcaa ccgggtctcc agcggcgtgc agtccttcga cgacgaccgg ctgcgccgcc
    19321 tgggccgccg gcacaccgcg gagcaggccg ggcgcatcgt gcacgccgcg cgggctgcgg
    19381 gtttcgagga cgtctccatc gacatcatgt ccggcttccc cgaccaggag gccgacgagc
    19441 tggaccggac cgtcgaccgt gcccttgagc tgccggtcaa ccacctctcg ctgtactcgt
    19501 tccggcccac cccgggcacg ttcatgcgcc gccggatgga ctcctcggag cggcggacgt
    19561 acctgcgccg ccagcaggcg ctgttcacgc gggcccgccg ggcgatcgag ggcttcggcc
    19621 tcagcgagta cgccaacggc tacttcggca aggtgtcgcc gttcgcctcc atgtacttcc
    19681 agcaccgcgc cgacaccgtc ggcctgggct cgggcgcgat ctccctggtg gaccagcggt
    19741 tcaagtccca ccagaagggc ctgctgcact cctacgtcga cgatccgctc gccttcgaca
    19801 tcgacgtgcc ggcgggccag gaccgcgtcc tggtgtcgct gctgcaggcc gggctcgcca
    19861 tgttcgacgg catcccccgc gaggactggc ggcagcgcac cggcacggac ctcgccgagg
    19921 tgctgctgcg gcccacggtc gcgcccctcg cggacttcct gcgcggccgc ggcctggtcg
    19981 aggacgacca cggcatccgc ctgccgcgtg acatcgccgg tctcaccctg atcgagctgg
    20041 ccttcgagat ggccatgtcc cagccggagc tggtgtgacc tcgggaccgg ggcaggcccc
    20101 ggccgaggcg gcacacgcag ccggggcggc ctggctggag atcgggctcg acgcccccgc
    20161 cgacgccgta cccgccctgg tcgccggtgt cgtgcggccg ctgctgcggg agcccgcgga
    20221 gccgggggcc gagcccgtgc ccgggttctt cctgcggggc gtcggcgcgg cccagcccgc
    20281 cctggtcgtc cagctggagg tgacccccgg cacggacctc gccgagccgt acgccgcccg
    20341 ggcccgcgcg ctcgccgccg ggctgggcct ccccgtgcag gtcgcggccg gccgggcgac
    20401 gctcgtcccg ctcgccggct cggtcttcgc gggggcggcc ctcggcccgg tgacccgcgc
    20461 cgcgctggcc gccgtatgcc ccgcgctgct caccgccacc gaggccgcgg aacagggcag
    20521 gcccgccctg ctggccagtg ccgccgaact catgtccgcg catctgcgcg cggtcagcgt
    20581 ctccgcggcc cccggccccc gccagtggga ggaactgcgc gagggcgtgc cgctcggctt
    20641 cctcagctac cgctcgcacg cggaggcgtt cctggcctcc agccgcgacc cgaaggccgc
    20701 gcaggcgatg atggacgcga agtacacccg cgccgcggcc accctggagc gcctggtcga
    20761 cggcgtcctc acccagtgcg aggagcgcgg cccggtggtc tccctgccgg cgcggcagtg
    20821 gtacgaggcg atgcgcgccg ccaagcccgc ggtgaccgag ctgttccgcg ccggaaccga
    20881 cctcgccctg gacaccgagg agcagccccc ggacaccggc ccggacggca agggcctgtc
    20941 cgaaagcgcg ttccaccgca ttgtcgaggg ctccgacggg ctgcgtgact tcctcgaccg
    21001 cgacccgtcc tttctggcca cccgactgct gaccagcctg ctctaccttt ccctgagcag
    21061 cgtcggcatc gccctggcgg aacggtattt cctctgctac gcggtgagcc gcgcctgtga
    21121 gtcgatcttc gacaccgacg ccctcaccgt cctgtccggt ctggcccgga cctccctggc
    21181 gtcctgacgc tccgacaccc tccctgacgt cggttttcgg ccgaatccat gcccggaacc
    21241 cgtgatcgac gggccgggcg ggaccggcct cttcccatgc accgggcgct ccccgcagaa
    21301 tcacgttccg atataaggcc cgaccggata ccgccaagcg gcgatccggc accgggacac
    21361 atgaagtagc atcgcgccca gataaggaca ttcaccgcca gaaacgttca aaaagatcac
    21421 cgagagatca ctgaccgagc ctgctccacc acgagcaatg ggggaacatg aaagctcaag
    21481 agctggaacg tgaggcgtga tcccggcagg gcgccgcacg gcgcggtcat cccgcgccca
    21541 cgcggcgccc tgccgcgtat gccggtttcc ccacgtcgct tccacacacc gggagatgcg
    21601 atgtcgtcag cacggtcgat ccacttgtgc accaccgcaa cgggggagtt cgatggagat
    21661 cgatgtcctg ggaccgcttg aggtctcgca gaagtccgct tcgattgtcc cgacggcttc
    21721 caagccgcgc accgtcctgg cgatgctcgc cgtctacacc aaccggctgg tccccctgcc
    21781 ctccctcatg ggagaactct ggggacccga accgccggcc accgcgaaga cggccgtaca
    21841 ggggtacatc ctgcatctgc gcaaacgtat cgccgagtcc gccgcgcgcc gcccaccggg
    21901 ccagttcccc gaggccaagg acatcctggt caccctcccc ggcggctatc tgctgcgcgc
    21961 cccgggaacc gcggtggtcc tggagcagtt cgagcagctg gcctgcgccg gacaccgcgc
    22021 ccgggagaag ggcgacttcg aggccgcctc gcggagcttc accgaggccc tcggcctgtg
    22081 gcgcggccgc gccctcgccg acgttgaggt gggcccccag ctgggcatag aggtgcagcg
    22141 gatcgaggag gcccggctca acgtcctcga ccgcaggatc gaggccgacc tccggctcgg
    22201 ccgccatcac gaactcctcg gtgagctgcg gagcgtcacc gcccaccacc ccacccatga
    22261 gggcttctgc gcccacctca tgctggcgct ctaccgctcc ggccgccgct gcgaggcact
    22321 cgacgcctac cagcgcatgc gcaccacgct ggtgaacgaa ctgggactgg aaccctcccc
    22381 gtccctgcgc cgcctccagc gctccctgct ggtctccgac cgcgaactcg acgaactcaa
    22441 cgtcacctgg gacgtcgcca cgttctgacc ccgcccggcg aacgccgaag ggcggccacc
    22501 ccgcacgggg tgaccgccct tcgtctcatg cgatcgctcg cttactggtt gtacggaccg
    22561 tagtcgtagt cctccagcgg aacggcctgg ccggagcccg tgccgaacgg cgagtagtcg
    22621 atgtcgtcgt agccgacggc cgagtacatc gcggccttgg cctcctcggt cggctcgacc
    22681 cggatgttgc ggtagcggga cagacccgta ccggccggga tgagcttacc gatgatgacg
    22741 ttctccttga ggccgatcag ggagtcggac ttggcgttga tcgccgcgtc cgtgaggacc
    22801 ctggtcgtct cctggaagga cgccgccgac agccaggact cggtcgccag cgaggccttg
    22861 gtgataccca tgagctgcgg acgaccggag gccgggtgac cgccctcctg gaccacacga
    22921 cggttctcgt gctcgaactt cgagcgctcg accagctcac cgggcagcag ctcggcgtcg
    22981 ccggactcga tgatcgtcac acggcggagc atctgccgga tgatgatctc gatgtgcttg
    23041 tcgtggatcg acacaccctg cgagttgtac accttctgga cctcgccgac caggtggacc
    23101 tggacggcac gctggcccag gatgcgcagc acgtcgtgcg ggttggtggc acccacggtg
    23161 agcttctggc ccacctcgac gtgctcgccc tcgctgacca ggagacgggc gcgcttcgag
    23221 atcgggtacg ccgtctcgtc gctgccgtcg tccggcgtga tgacgatctt cttggtcttc
    23281 tcggtctcct cgatccgcac gcggccggag gcctcggaga tcggggcgac acccttcggg
    23341 gtacgggcct cgaagagctc gacgacacgc ggcagaccct gggtgatgtc gtcaccggcc
    23401 acaccaccgg tgtggaaggt acgcatcgtc agctgggttc cgggctcacc gatggactgg
    23461 gcggcgatga tgccgaccgc ctcaccgatg tcgaccagct tgccggtggc gagcgaacgg
    23521 ccgtagcaca tcgcgcaggt accgacggcg gactcgcagg tcaggaccga gcgggtcttg
    23581 acctcctcga cgccgcgctg gacgagctcc tcgatgagga cgtcgcccag gtcggtgccg
    23641 gccggggcca gcacctggcc gtcgaccacg atgtcctcgg cgaggcagcg cgcgtacacg
    23701 gacgtctcga cgtcgtccgc cttgcgcagc acgccgtccg cgccccgctc cgcgatcttg
    23761 agcttgaggc cgcggtcggt gccgcagtcc tcctcgcgga tgatgacgtc ctgggagacg
    23821 tcgaccagac gacgggtgag gtaacccgag tcggcggtac gcagagcggt gtccgccaga
    23881 cccttacggg caccgtgcgt ggagatgaag tactccagca cggacagacc ctcacggaac
    23941 gaggccttga tgggccgcgg gatcgtctcg ttcttcgcgt tcgacaccag accacgcata
    24001 ccggcgatct gacgcatctg catcatgttg cctcgtgcac ccgagttcac catcatgaag
    24061 atcgggttgg tcttcgggaa gttgtcgttc atcgcctcgg cgacctcgtt ggtcgccttg
    24121 gtccagatcg cgatgagctc ctgcgtgcgc tcgtccttgg tgatcagacc gcgctcgtac
    24181 tgcttctgga ccttctcgtc ctgcgcctcg tagcccttga cgatctcctt cttcgcctcg
    24241 ggaacgacga cgtcggagat ggccacggtg acaccggaac gggtcgccca gtagaagccg
    24301 gacgccttca ggttgtcgag cgtcgccgcc acgatgacct tcgggtagcg ctcggcgagg
    24361 tcgttgacga tctcggagag ctgcttcttg ccgacctcgt agtcgacgaa cgggtagtcc
    24421 tcgggcagca gctcgttgaa gagcgcacgg cccagcgtgg tcttcagggt gaagctgtca
    24481 ccctgctgcc actccggctc gccctcctcg cgcaccggcg ggacccagcc gcgcggcggg
    24541 atggtgccca ccgggaagcg gatgtgcacc ggcgcctgca gcgacagctc gcccgcgtcg
    24601 aacgccatga tcgcctcggc gaccgacgcg aacgcacggt cctcgccctt gacgccccgg
    24661 ccctcggcgt ccgtggtgag gaagaacaga ccgaggacca tgtcctgcgt cggcatcgtc
    24721 accggacggc cgtcggccgg cttgaggatg ttgttcgagg acagcatcag gatgcgggcc
    24781 tcggcctgcg cctccgcgga cagcggcagg tgcacggcca tctggtcacc gtcgaagtcc
    24841 gcgttgaacg cggtgcagac gagcgggtgg atctggatgg ccttgccctc gaccagctgc
    24901 ggctcgaagg cctggatgcc caggcggtgc agggtgggcg cacggttcag cagcaccggg
    24961 tgctcggcga tgacctcttc gaggacgtcg tacaccacgg tgcggccacg ctcgaccatc
    25021 cgcttggcgc tcttgatgtt ctgcgcgtgg ttcaggtcga ccaggcgctt catcacgaac
    25081 ggcttgaaca gctccagcgc catcgccttc ggcagaccgc actggtgcag cttcagctgc
    25141 ggaccgacga cgatcacgga acgcgccgag tagtcgacac gcttgccgag caggttctga
    25201 cggaagcggc cctgcttgcc cttcagcatg tcgctgaggg acttcagcgg gcggttgccg
    25261 ggaccggtca ccggccggcc gcgacgaccg ttgtcgaaga gggcgtcaac agcctcctga
    25321 agcatgcgct tctcgttgtt gacgatgatc tccggagcac ccaggtcgag caggcgcttc
    25381 agacggttgt tgcggttgat gacacggcgg tacaggtcgt tcaggtcgga ggtcgcgaag
    25441 cggccaccgt ccagctgcac catcggacgc aggtccggcg ggatgaccgg gacgcagtcc
    25501 aggaccatgc ccttggggct gttggaggtc tgcaggaacg ccgagacgac cttcaggcgc
    25561 ttgagcgcac gggtcttctt ctggcccttg ccggtgcgga tgatctcccg gagcttctcc
    25621 gcctcctcct ccaggtcgaa ggactccagg cgcttctgca gcgccgcggc acccatcgaa
    25681 ccgtcgaagt acgtgccgaa gcggtcacgc agctcgcggt agagcagctc gtcgccctcc
    25741 aggtcctgga ccttgaggtt cttgaagcgg gtccacacct cgtcgaggcg gtcgatctcg
    25801 cgctgcgcac ggtcgcgcag ctgcttcatc tcacgctcgg caccctcgcg caccttgcgg
    25861 cgcacgtcgg ccttggcacc ctcggcctcc agctcggcca ggtcggcctc gagcttcttg
    25921 gcgcgggcct ccaggtcggc gtcccggcgg ttctcgatct gctggcgctc gaccgagacg
    25981 tgcgcctcca gggagggcag gtcgcgggta cggcgctcct cgtcgacgta cgtgatcatg
    26041 tacgccgcga agtagatgac cttctccagg tccttcgggg cgaggtcgag caggtagccc
    26101 agccgcgacg gaacaccctt gaagtaccag atgtgcgtga cgggggcggc cagctcgatg
    26161 tggcccatcc gctcacggcg caccttggcg cgggtgacct cgacgccaca gcgctcgcag
    26221 atgatgccct tgaagcggac gcgcttgtac ttgccgcagt agcactccca gtcccgggtc
    26281 ggaccgaaga tcttctcgca gaagagtccg tccttttcgg gcttgagcgt gcggtagttg
    26341 atggtctccg gcttcttgac ctcgccgtgg ctccactgac ggatgtcgtc agcggtggcc
    26401 agaccgatcc ggagctcgtc gaagaagttg acgtcgagca ctatgcgtca atccctctca
    26461 gggttgtaag tcttggggtc tgaaacgggg gtcctggggc cggccgggga ctcagcggaa
    26521 tgcaccgagt ccccgtaccg gactcccgtc agacctcttc gacgctgctc ggctcgcgcc
    26581 gggacaggtc gataccgagc tcctccgcag cgcggaagac gtcctcgtcg gtgtcgcgca
    26641 tctcgatgga catgccgtcc gaggacagca cctccacgtt gaggcacagg gactgcattt
    26701 ccttgatgag caccttgaag gactcgggaa tgccgggctc agggatgttc tcgcccttga
    26761 cgatggcctc gtagaccttc acgcggccgg tgacgtcgtc ggacttgatg gtcagcagct
    26821 cctggagggc gtaggcggcg ccgtacgcct ccagcgccca cacctccatc tcaccgaagc
    26881 gctggccacc gaactgggcc ttaccaccca gcggctgctg ggtgatcatc gagtacggac
    26941 cggtcgagcg ggcgtgcagc ttgtcgtcga ccaggtggtg cagcttcagg atgtacatgt
    27001 agccgaccga gatcgggtcc gggaacggct caccgctacg gccgtcgaac agtcgcgcct
    27061 tgccggacgg gagcaccatg cgctcgccgt cgcggttcgg gatggtgtgc tgcagcagac
    27121 ccgcgagctc gtcctcacgc gcaccgtcga agaccggggt ggcgacgttg gtgccgggct
    27181 cgaccttgtc ggcgccgatc gcctggaggc gctgcgccca ctcgtccgcc aggccggaga
    27241 cgtcccagcc gcggctggcg agccagccga ggtggatctc caggacctgt cccgggttca
    27301 ttcgggacgg cacacccagc gggttgagga tgatgtcgac cggggtgccg tcctccagga
    27361 acggcatgtc ctcgatcggc aggatcttgg agatgacacc cttgttgccg tgacggccgg
    27421 cgagcttgtc accgtcggtg atcttgcgct tctgcgcgac gtagacgcgg accagctggt
    27481 tcacacccgg cggcagctcg tcgccctcct cgcggtcgaa gacgcgcaca ccgatgacct
    27541 tgccggtctc gccgtgcggc accttcagcg aggtgtcacg gacctcacgg gccttctcac
    27601 cgaagatggc gcgcagcagg cgctcctccg gcgtcagctc ggtctcaccc ttgggcgtga
    27661 ccttgccgac gaggatgtca ccggcgatga cctcggcacc gatgcggatg atgccgcgct
    27721 cgtcgaggtc ggcgaggacc tcctcggaga cgttcgggat gtcccgggtg atctcctcgg
    27781 ggccgagctt ggtgtcacgg gcgtcgacct cgtgctcctc gatgtggatc gaggagagga
    27841 cgtcgtcctg cacgaggcgc tgcgacagga tgatcgcgtc ctcgtagttg tgaccctccc
    27901 acggcatgaa cgccacgagc aggttcttgc cgagcgccat ctcgccgttc tgggtggccg
    27961 ggccgtcggc gagcacctgg cccgtgatga cgcggtcgcc ctcgttgacg atgaccttct
    28021 ggttgaccga ggtgccctgg ttggaccggg agaacttggc caggcggtac gtgatgtacg
    28081 tgccgtcgtc gttggcggtg gtgatgtagt ccgcggagac ctcctggacc acaccgtcct
    28141 tctcggcctt gaccacgtcg ccggcgtcga cggcggagcg gtactccatg ccggtgccga
    28201 cgagcggggc ctcggactta atcagcggca cggcctggcg catcatgttc gcgcccatga
    28261 gggcacggtt ggcgtcgtcg tgctcgagga acgggatcat ggcggtcgcg accgacacca
    28321 tctggcgcgg cgagacgtcc atgtagtcca cgtcctcggg ggcgacgtag tcgacctcgc
    28381 cgccacggcg gcggaccagg acgcgggcct cctcgaaccg catgtcggcg gtgagcggcg
    28441 cgttggcctg cgcgatgacg aagcggtcct cctcgtcggc ggtcaggtag ttcacctcgt
    28501 cggtgacctg gccgtcgacg accttgcggt acggggtctc gacgaagccg aacgcgttga
    28561 cgcggccgta ggtggcgagc gagccgatca gaccgatgtt cgggccttcg ggggtctcga
    28621 tcgggcacat gcggccgtag tgcgacgggt ggacgtcacg gacctcgaag ccggcccgct
    28681 cacgggagag accacccggg ccgagcgcgg acagacgacg cttgtgcgtc agcccggaca
    28741 gcgggttgtt ctggtccatg aactgggaca gctggctggt gccgaagaac tccttgatgg
    28801 aggcgacgac cggccggatg ttgatcaggg tctgcggcgt gatcgcctcg acgtcctggg
    28861 tcgtcatccg ctcgcggacg acacgctcca tacgggccag acccgtgcgg acctggttct
    28921 ggatgagctc gccgacgctg cgcaggcggc ggttgccgaa gtggtcgatg tcgtcggtct
    28981 cgacgacgac cggctggccg ttgtcgccga cggtctcggt ctcaccggcg tgcagcttca
    29041 ccaggtactt gatcgtcgcg atgatgtcct cgacggtcag gatcccggcg tccagcgggg
    29101 tgtccgtgcc cagcttcttg ttgaccttgt agcggccgac cttggccagg tcgtagcgct
    29161 tggggttgaa gtagaggttc tccagcagcg tctgcgcggc ctcacgcgtg gggggctcgc
    29221 ccgggcgcag cttgcggtag atgtcgagca gcgcgtcgtc ctggccctgg gtgtggtcct
    29281 tctccagggt ggcgcgcatg gactcgtact cgccgaactc ctcgaggatc tgctcggtgg
    29341 tccagccgag cgccttgagc aggacggtca cggactgctt gcgcttgcgg tcgatgcgga
    29401 caccgaccat gtcgcgcttg tcgatctcca tctccagcca ggcaccccgg gacgggatga
    29461 tcttggcgga gaagatgtcc ttgtcggacg tcttgtcgat gctggagtcg aagtagacac
    29521 cgggggaacg gaccagctgc gacaccacga cacgctcggt gccgttgatg acgaacgtgc
    29581 ccttgttcgt catgagcggg aagtcgccca tgaagacggt ctgggacttg atctcgccgg
    29641 tctcgttgtt ggtgaactcg gccgtgacga agagcggcgc ggcgtaggtg aagtcgcgct
    29701 ccttgcactc gtcgatcgag ttcttcggcg gctcgaagcg gtggtcgcgg aaggtcagcg
    29761 acatcgaccc cgagaagtcc tcgatcgggg agatctcctc gaagatctcc tcgaggccgg
    29821 acttggtggg gacgtcctga ccgttctcga gagcctcctc gacccgactc tgccaggcgg
    29881 tgttgccgag cagccagtca aagctctcgg tctgcagcgc gagcaggttc ggaacctcga
    29941 gaggctcctt gatctttgca aaggagatgc gcagcggggc ggtgctggcg ccgttgttcg
    30001 tattcgcggt cgaggcagtg cgcgaggcgg ccaagagggg gtccttccga gggctcggac
    30061 tcactacgcg cgtaccggcc cctcccccgt acacagagac agagatccca ggtcggagat
    30121 catctgtcgg tcagtgctcg agtgagggca gacccctggt gacgggcagg ggacagctaa
    30181 caggcagcgc aaagggtcag tgtagccaca aggcacactg atgtccagtc ccgcattttc
    30241 ggagactcca ctgttctcaa cgcctgcggc atgcctgccc tcaacgcacg ttgatactgc
    30301 cctcttcgtc gtcgatccat gcctcggatt cggatccttg tgacgacgcg tcctgagaat
    30361 tgcgcgctgc gtgcggttcg tcaaggcccc ccttgcccga accggggcgg ccgagacacg
    30421 acgaagatca ccttacccct cacgaacaca ggtgcaaggc agcccgggcc gtcccccggg
    30481 gaacgccgaa gggcgaccac ccggatggat gatcgccctt cggtgcgttc gcgttacagc
    30541 ccctgagggc cgttcatgcg gtcgcgaagg tcttacttga cctcgacgga ggcgccggcg
    30601 cccttgaggg cctcggcggc cttgtcggcc tgctccttgt tgaccttctc gaggaccggc
    30661 ttcggggtgc cgtcgacgag gtccttggcc tccttcaggc ccagggaggt cagctcacgc
    30721 acgaccttga tgacctggat cttcttgtcg ccggcgccgg tgaggatgac gtcgaactcg
    30781 tccttctcct cctcggcctc ggcggcggcg ccaccggcgg caccaccggc gacgacgacc
    30841 ggcgcggcag cggcggcggt gacgtcgaac ttctcctcga acgccttcac gaactcggag
    30901 agctcgatga gggtcatctc ctcgaactgc gcgagcagct cgtcctgggt cagcttcgcc
    30961 atgatggcgg tccttccact caattcggca ggtgccggat gtactggata aggcgggcgt
    31021 acgtcgggcc cgctaggacc ctcgccggtc ggtcggcgtg ggtcggaaag cgagccgaat
    31081 tactcggcac cgccctgctc ggcctgcttg gcgcgcagcg cgtccacggt gcggacgagc
    31141 ttcgacggca gcgcctggaa gacggaggca gcctgggact gcttcgcctt gaaggcaccg
    31201 gccagcttgc tgagcagaac ctcgcgggac tcgaggtccg caagcttctt gatctcgtcg
    31261 gcggacagcg ccttgccgtc aaggacaccg cccttgatga cgagattcgg gttttccttg
    31321 gcgaagtcac ggagaccctt cgccgactcc accgggtcac cggtgacgaa ggcgacagcc
    31381 gtcggaccgt tgaacaggtc gtccagcgtc gtgatcccgg cctcgttggc cgcaatcttg
    31441 gtcagcgtgt tcttcaccac ggcgtactgg gcgttctcac cgagtgcgag acgcagcttc
    31501 ctggtctgcg cgacggtgag accgcggtac tcggtcagca cggcagcaga cgagttgcgg
    31561 aacttgtccg tcagctcggc aaccgcggca gccttgtcgg gcctcgccat agagcctcgg
    31621 cctccttccg ggtgattcgg accgcgcgga cccgaaggag gactgggaaa aacgaaacgc
    31681 cccggcgcag gcgcacgggg cggactcaac cggttcgcac gtgcgtgaac acacgtatgc
    31741 tccgggagtt cttccacagt cacctgcgcg ggtcgtccgc attgaacagc ggatccttcg
    31801 gccaccgacc ccgaatgggg cacggcaacg accagcggtc tttggcttct gtaggagagt
    31861 acgggacggg tacgccgtca agcaaatcgc ccctacgggc gtcagccctg gacgcccttc
    31921 atcatctcgg cgaggtcggc gacgtccttc gccggcggcg ccgtgacggt gacgggcttg
    31981 ttcacgtcgt agaaggtgat cgtcatgtcg agcgggccct tgtcggcgtc gccgcgcatc
    32041 cggaaccgct tggtgtggtc ctcgccgtcg acccacaggt ccatggagag cttgtcgatg
    32101 cccagcttct cgaactcgtc gaggctcttc tgccgcttgt cgcgactcgc cttgtcggtg
    32161 cccttcagcg acttctccag ggcgtcgagg gtggcggtgc cctggtagtg ggtggtcttc
    32221 accccgtcga cggtctcggc gccgacctcg cgcacgtcgt cggcgccggc caggaaggtg
    32281 gactgggccg ccgggttctg ctcggccgtg gccccggccc cggcgagcgg gttggcctcc
    32341 ttgcccgcct tggacatgtc gaacttgatc cagctcttgc cgtccatctc gccggccgcc
    32401 tcggcgccac cgttgatgta catcgccttg tccacgaacc ggatctcgac ctgtccggcg
    32461 tcggcctggt cctcgggcgt gatcttcatg ctgagggcgg gcggcttcgt gctcatcgcg
    32521 gcctcgccgc gcacccggcc ctcgccgggc acccggccgt cgagccggta gcggaacgag
    32581 gtgacggcgt cggcgttctt cgcggcccgg gcgacggccg ccgcgggctc caggtccgga
    32641 gactgctcgc ccttgccgca gccgacggca cccgccagga gcagcccggc gagggcagcg
    32701 gtggacacgg cacgcttcat cgatttcccc cccaaggaaa cacatggccg ccacacagcg
    32761 gccggacgag cctaacccgc gggttaccga tcagtcgctc gatttgtcag gacccctggc
    32821 cgcccatcag tgcctcgaag tcctcggtgt ccccgtccgg cggccgctgt acggcgaccc
    32881 gcacgccgta ggtgtcgtag tacgccgtct gggtcatcgg gccggacgtc atctcggcct
    32941 tctccacctt cttgaccagc agattcttct cgtcgaccca gatgtcgacc tgctccgcgg
    33001 tgaccccggc gtcggtgagc tgccggcgca gggccacgtc gccgagcgcg gagacgtcga
    33061 cggtgccggt gtagtgccgg gtggcgcggc cccctaccgt ctcccggccc gtctcgcgca
    33121 ccgtgccgga ggccagcagg agccgcacgg gcagcacggg cgcggtgtcg cggagctggt
    33181 cgcggaggta ggcgccggag tcgccgggca gctcggcgag gtcgtcgaag tcgtagcgga
    33241 tccagtgccg gccgcccatc cgccgggcga agtcctcgcc gacccgggcg tagtaggcgt
    33301 cgggcagcag acgggcctcc atggtggtgg tgccgagctt gcgcaggggc tcggtgaggc
    33361 tgccgcctgt gtaggtgatg cgcagggtgc cggtggagtc gccggcccag tccagggcgc
    33421 cctcggtgcg ggtggagagc aggtcgccca tggccgtggt ggagctgatc cgggccgagc
    33481 ccgccccggc gacggcccgc tcgacggcgc gcagcgcgtc cgccgtacgg ggatcggggc
    33541 gcggtgcggc gctcacggtg ccgcccgtgg cgtccgggcg ggcggcgccg tcgtcggagc
    33601 cgccgcaccc ggtcagggcc gtcagcgcgg cgacggcggc cagcagggcc gtcgtggtcg
    33661 gcgcggctcc ccgcgggcgg gcggtgcccc tgtgcctcat gtctccccct cggtccccgt
    33721 gatcgccacg ctaacccggc gaggggcccc gggggtacgg gaacgggccc cgcacctggg
    33781 aaggtgcggg gcccgtgacc gactcggtga gccgtcaggc tcagaccgcg gccgggtcct
    33841 cctcgacgag gaggttgcgg gtgcggttcg ggtcgacggg gatgccgggg cccatcgtgg
    33901 tggtgatggc ggccttcttg atgtagcgac ccttggcggc ggacggcttc agacggagga
    33961 tctcctccag cgcggcgccg tagttctcca ccagcttggc gtcgtcgaag gacgccttgc
    34021 cgatgatgaa gtgcaggttc gagtgcttgt cgacgcggaa ctcgatcttg ccgcccttga
    34081 tgtcggtgac ggccttggtc acgtcggggg tgacggtgcc ggtcttcggg ttcggcatca
    34141 gaccacgggg accgagcacg cggccgaggc ggccgacctt gcccatgagg tccggggtgg
    34201 cgacgacggc gtcgaagtcc aggcggccct tggagacctc gtcgatcagc tcgtcggcgc
    34261 cgacgatgtc ggcgcccgcg gcacgcgcgg cctcggcacg gtcgccggtc gcgaagacca
    34321 ggacccgggc ggtcttaccg gtgccgtgcg gaaggttcac ggtgccacgg accatctggt
    34381 cggccttgcg cgggtcgaca cccagacgga aggcgacctc gacggtggcg tcgaacttgg
    34441 tcgtggaggt ctccttggcg agacggacgg cctcgagcgg ggcgtacagc ttctcccggt
    34501 cgaccttggc gtccgcagcc ttgagagcct tgctgcgctt gctcacgtga tgctcctgtg
    34561 ttggctagga gtcgtggtac gggccgagca ggcccttcca cgctgttctg caggggggtt
    34621 gaggtcagcc ctcgacggtg acgcccatgg aacgggcggt accctcgatg atcttcgccg
    34681 cggcgtccag gtcgttggcg ttgaggtcgg gca
//
