BGC0000613: thiomuracin A biosynthetic gene cluster from Nonomuraea sp. Bp3714-39
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Location: 1 - 15,586 nt. (total: 15,586 nt).
This entry is originally from NCBI GenBank FJ461360.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000613
Short description thiomuracin A biosynthetic gene cluster from Nonomuraea sp. Bp3714-39
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
FJ461360.1
via Gene expression correlated with compound production
Compounds
  • thiomuracin A
Species Nonomuraea sp. Bp3714-39 [taxonomy]
References
Chemical products information
thiomuracin A Evidence:
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C59H50N14O12S6
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACS83777.1
  • tpdI
 1 - 1212 (-) coproporphyrinogen III oxidase
  • Scaffold biosynthesis
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  • ACS83778.1
  • tpdJ1
 1209 - 2372 (-) cytochrome P450 monooxygenase
  • Scaffold biosynthesis
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  • ACS83779.1
  • tpdJ2
 2369 - 3589 (-) cytochrome P450 monooxygenase
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    • ACS83780.1
    • tpdR
    		 3600 - 4331 (-) TetR transcriptional regulator
    • Regulation
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    • ACS83781.1
    • tpdA
    		 4677 - 4826 (+) thiomuracin prepropeptide
    • Scaffold biosynthesis
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    • ACS83782.1
    • tpdB
    		 4866 - 7478 (+) dehydratase
    • Scaffold biosynthesis
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    • ACS83783.1
    • tpdC
    		 7475 - 8290 (+) dehydratase
    • Scaffold biosynthesis
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    • ACS83784.1
    • tpdD
    		 8287 - 9246 (+) hypothetical protein
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      • ACS83785.1
      • tpdE
      		 9243 - 10529 (+) dehydrogenase
      • Scaffold biosynthesis
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      • ACS83786.1
      • tpdF
      		 10526 - 12418 (+) hypothetical protein
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        • ACS83787.1
        • tpdG
        		 12411 - 14255 (+) cyclodehydratase
        • Scaffold biosynthesis
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        • ACS83788.1
        • tpdH
        		 14252 - 15586 (+) peptidase
        • Scaffold biosynthesis
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        Biosynthesis information
        Annotation changelog

        Entry version: 4

        Date
        Changes
        Submitters
        Reviewers
        2022-10-07
        Update chemical activity to schema version 2.11
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 3

        Date
        Changes
        Submitters
        Reviewers
        2022-09-15
        Updated bioactivity data
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 2

        Date
        Changes
        Submitters
        Reviewers
        2019-10-16
        Migrated from v1.4
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        2019-10-16
        Updated compound(s) information (NPAtlas curation)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 1

        Date
        Changes
        Submitters
        Reviewers
        2015-06-12
        Submitted
        • (ID: O4PIO7VEX2IICIP2RGFFKN3C)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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