LOCUS       BGC0000617              6455 bp    DNA     linear   BCT 14-JUL-2016
DEFINITION  Bacillus coagulans plasmid pI4 coagulin operon, complete sequence;
            and Mob/Pre (mob/pre) gene, complete cds.
ACCESSION   BGC0000617
VERSION     BGC0000617
KEYWORDS    .
SOURCE      Weizmannia coagulans (Bacillus coagulans)
  ORGANISM  Weizmannia coagulans
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Weizmannia.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:56:14
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..6455
                     /db_xref="taxon:1398"
                     /mol_type="genomic DNA"
                     /organism="Weizmannia coagulans"
                     /plasmid="pI4"
                     /strain="I4"
     protocluster    1..6455
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1088:4474]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1089..4474
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..6455
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..6455
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000617"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..6455
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1089..1277
                     /gene="coaA"
     CDS             1089..1277
                     /codon_start=1
                     /gene="coaA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_II"
                     /gene_kind="biosynthetic"
                     /note="pediocin-like bacteriocin; similar to PedA from
                     Pediococcus acidilactici"
                     /product="CoaA"
                     /protein_id="AAG28763.1"
                     /sec_met_domain="Bacteriocin_II (E-value: 6.2e-23,
                     bitscore: 68.9, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIEKLTEKEMANIIGGKYYGNGVTCGKHSCSVDWGKATTCIIN
                     NGAMAWATGGHQGTHKC"
     gene            1089..4474
                     /gene="coagulin operon"
     gene            1315..1653
                     /gene="coaB"
     CDS             1315..1653
                     /codon_start=1
                     /gene="coaB"
                     /note="immunity protein; similar to PedB from Pediococcus
                     acidilactici"
                     /product="CoaB"
                     /protein_id="AAG28764.1"
                     /transl_table=11
                     /translation="MNKTKSEHIKQQALDLFTRLQFLLQKHDTIEPYQYVLDILETGIS
                     KTKHNQQTPERQARVVYNKIASQALVDKLHFTAEENKVLAAINELAHSQKGWGEFNMLD
                     TTNTWPSQ"
     gene            1677..2201
                     /gene="coaC"
     CDS             1677..2201
                     /codon_start=1
                     /gene="coaC"
                     /note="accessory protein; similar to PedC from Pediococcus
                     acidilactici"
                     /product="CoaC"
                     /protein_id="AAG28765.1"
                     /transl_table=11
                     /translation="MSKKFWSNIFLALGVFLAFAGVATISVSADSSATIESNTSSKIID
                     GATYEENIKGVIPITLTQYLHKAQTGEKFIVFVGFKECVHCRKFSPVMKQYLQQSQHPI
                     YYLDYGNNGSFSMASQKQITDFYSTFATPMSFMGTPTVALLDNGKVISMTAGDDTTLSD
                     LQQITADYNNQ"
     gene            2300..4474
                     /gene="coaD"
     CDS             2300..4474
                     /codon_start=1
                     /gene="coaD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 285.7; E-value:
                     1.3e-86)"
                     /gene_kind="biosynthetic"
                     /note="ABC transporter; similar to PedD from Pediococcus
                     acidilactici"
                     /product="CoaD"
                     /protein_id="AAG28766.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.3e-48, bitscore:
                     151.8, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1236.0,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWTQKWHKYYTAQVDENDCGLAALNMILKYYGSDYMLAHLRQLAK
                     TTADGTTVLGLVKAAKHLNLNAEAVRADMDALTASQLPLPVIVHVFKKNKLPHYYVVYQ
                     VTENDLIIGDPDPTVKTTKISKSQFAKEWTQIAIIIAPTVKYKPIKESRHTLIDLVPLL
                     IKQKRLIGLIITAAAITTLISIAGAYFFQLIIDTYLPHLMTNRLSLVAIGLIVAYAFQA
                     IINYIQSFFTIVLGQRLMIDIVLKYIHHLFDLPMNFFTTRHVGEMTSRFSDASKIIDAL
                     GSTTLTLFLDMWILLAVGLFLAYQNINLFLCSLVVVPIYISIVWLFKKTFNRLNQDTME
                     SNAVLNSAIIESLSGIETIKSLTGEATTKKKIDTLFSDLLHKNLAYQKADQGQQAIKAA
                     TKLILTIVILWWGTFFVMRHQLSLGQLLTYNALLAYFLTPLENIINLQPKLQAARVANN
                     RLNEVYLVESEFSKSREITALEQLNGDIEFNHVSFNYGYCSNILEDVSLTIPHHQKITI
                     VGMSGSGKTTLAKLLVGFFEPQEQHGEIQINHHNISDISRTILRQYINYVPQEPFIFSG
                     SVLENLLLGSRPGVTQQMIDQACSFAEIKTDIENLPQGYHTRLSESGFNLSGGQKQRLS
                     IARALLSPAQCFIFDESTSNLDTITEHKIVSKLLLMKDKTIIFVAHRLNIASQTDKVVV
                     LDHGKIVEQGSHRQLLNHNGYYARLIHNQE"
     gene            complement(4594..6018)
                     /gene="mob/pre"
     CDS             complement(4594..6018)
                     /codon_start=1
                     /gene="mob_pre"
                     /note="putative plasmid recombination enzyme; similar to
                     various Mob/Pre proteins from gram positive bacteria
                     plasmids"
                     /product="Mob/Pre"
                     /protein_id="AAG28767.1"
                     /transl_table=11
                     /translation="MSMLVARMQKMKANNLAGIERHNKRIYKNHSNEDIDGELSNSNYD
                     LMDRQGKYADIVKEIIDSQKKGNRAIRSDAVLVNEWIITSDKEFFRDMAPKERDRFFQE
                     ATNWFKERYGQQNIAYAQVHLDERTPHMHLGVVPMREGKLSAKNVFNRQELRAVQDELP
                     KHLQEKGFEIQRGKEESERKHLSVPEYKEAKEEAKKVKEETKELASKASQLAEFHNNVN
                     DRVKTLVERNKALEGEIERKKALVKEHVRRVDVLVSEVKQEKEPKRYHAAKSEPIYQPE
                     VRTELLRGRTVKMSSEEYNKMLASQRKLEKDHENVVKNFNVLADLYYHSEKEKQCLVAE
                     LAKANKAIPVQNEFFVPAFELQKAQQEIREKDKLIEQKNRIIGEQAEQIKGMEKAIMRC
                     AEFIRDMRKQAYDLVSDLAKRMGIVPLVNNLIHQEKEQQKEQKKQQKRLEIEVADRKPE
                     PPKKQKSRADDWGMER"
ORIGIN
        1 gaattccgaa gagaagagct cgaacagctg tgagaggaac ggaacaacca acaatttcgc
       61 atgctttctc cggcaatccg gaaaaaaatc cagggagaac ggggccgagt ttccaaaaat
      121 actggtacta ctacgggact gtcttgtatg gatggaactt tggaaaaaac taaccataat
      181 gaggagtggt cttatggtta taattgacaa aaagcaatta gatgatgcta tttcttatgc
      241 gatgcattcc ctttatctcg agggatttaa tgtgactgct gatgttgaaa aaacgtgcgg
      301 gctgtattaa caggtcagtt aagtatgaaa gagcttcttg aaaaaataaa ggatgcttaa
      361 tttatgatca gtcaatgtat tgtttatccg ggtactaatt ttaatcggtt atgcacaata
      421 ctccctagtt aaaaaaattt aagcatcccc ctattaaatt tttttaacta ggggtcattt
      481 ggaatttggc ttgctaggga ttcataaatt tcatttcgaa caaattcttc agcccgtaat
      541 tttaaatgat tgagatgacg ggttgttatg ggagccggat ctttttccat gagttgatca
      601 aaaatcagca aaaatttatc ttgcgtaatt ttcccatttt accaatggat gagcgtaatt
      661 ttgatcgtta cttgtaccct cctgaaagag attttaaatg aaaaggtggt aaagaagagc
      721 gacttgaggt tttaatcaga tataataaag gtgaatagaa atgatgccga caaaagaaga
      781 tgtagctgcg catataaaca aagtctataa acgttacaaa gaagctcaac gtgtattaaa
      841 atatctcgaa aaggaaaatg cccctaaccc aagaattaca gaaatgaaac gcatcgtaaa
      901 ttttttggaa caagagcata atacccaaaa attagctttt acactaactg aacttgctct
      961 aaaaaattct tatgctatac taattctata atcacgaagg aaaaataaag caggatgaat
     1021 cactccaaag atggggtcca ccttaaagcg cgtattaagg ataatttaag aagaaggaga
     1081 tttttgtgat gaaaaaaatt gaaaaattaa ctgaaaaaga aatggccaat atcattggtg
     1141 gtaaatacta cggtaatggg gttacttgtg gcaaacattc ctgctctgtt gactggggta
     1201 aggctaccac ctgcataatc aataatggag ctatggcatg ggctactggt ggacatcaag
     1261 gtactcataa atgctagcat tatgctgagc tggcatcaat aaaggggtga ttttatgaat
     1321 aagactaagt cggaacatat taaacaacaa gctttggact tatttactag gctacagttt
     1381 ttactacaga agcacgatac tatcgaacct taccagtacg ttttagatat tctggagact
     1441 ggtatcagta aaactaaaca taaccagcaa acgcctgaac gacaagctcg tgtagtctac
     1501 aacaagattg ccagtcaagc gttagtagat aagttacatt ttactgccga agaaaacaaa
     1561 gttttagcag ccatcaatga attggctcat tctcaaaaag ggtggggcga gtttaacatg
     1621 ctagatacta ccaatacgtg gcctagccaa tagtactgat aaaggggata ttgtagttgt
     1681 ctaaaaaatt ttggtcaaat atctttttag cattaggcgt ctttcttgct tttgcaggag
     1741 ttgctaccat atcggtgagt gctgacagtt ccgctactat agaatcaaat actagctcga
     1801 aaatcatcga tggtgcaact tatgaagaaa acatcaaggg cgttattcct attacgctaa
     1861 ctcaatattt gcataaagct caaactggag aaaaatttat tgtctttgtc ggattcaagg
     1921 agtgtgtgca ttgtcgtaaa ttttctccag tcatgaaaca gtacttacaa caaagtcagc
     1981 atcccattta ttacttagac tatgggaaca acgggtcttt cagcatggct tctcaaaaac
     2041 aaataactga tttttattca acttttgcaa cccccatgag ttttatggga acaccaactg
     2101 ttgccttgct cgataatggt aaggtgatat caatgaccgc tggtgatgat accactttat
     2161 ctgatttaca acagattact gctgattaca ataatcagta gtcacctggt taatatggtt
     2221 ttgtaaccaa tgtaaaaggc gatggatctt tgaaatcgtc tttttttatg cacaaatttt
     2281 aaagatcggt ggtttgctta tgtggactca aaaatggcac aaatattata cagcacaagt
     2341 tgatgaaaat gactgtggtt tagctgcact aaatatgatc ctaaaatact atggttctga
     2401 ttacatgttg gcccatcttc gacagcttgc caaaacaact gctgacggta caactgtttt
     2461 ggggcttgtt aaagcagcaa aacacttaaa tttaaatgcc gaagctgtgc gtgctgatat
     2521 ggatgctttg acagcctcac aattgccatt accagtcatt gttcatgtat tcaagaaaaa
     2581 taagctacca cactactatg ttgtctatca ggtaactgaa aacgatttaa ttattggtga
     2641 tcctgatcca accgttaaaa ccactaaaat atcgaaatca caatttgcta aagaatggac
     2701 ccagattgca attatcatag ccccaacagt taaatataaa cccataaaag aatcacggca
     2761 cacattaatt gatctagtgc ctttattgat taaacaaaaa agattaattg gactaattat
     2821 taccgcagca gctataacaa cattaatcag tattgctggt gcatatttct ttcagttaat
     2881 tatcgatact tatttgccgc acttgatgac taataggctt tcactagttg ccattggtct
     2941 gattgtagct tatgctttcc aagcaattat caactatata caaagttttt ttacgattgt
     3001 attaggacaa cgtctcatga tcgacatcgt tttaaaatac attcaccatc tttttgattt
     3061 accaatgaat ttttttacta cccgtcatgt cggtgaaatg acctcacgct tttctgatgc
     3121 aagcaaaatt attgatgcac ttggaagtac aacgctcacc ctttttttag acatgtggat
     3181 tttattagca gtagggttat ttttggccta tcaaaacatc aatttatttt tatgctcgtt
     3241 agttgtggtt ccaatttaca tctcgattgt ttggctattt aaaaaaactt ttaatcgttt
     3301 aaatcaagat acaatggaaa gcaatgcagt tcttaattct gctattattg aaagtctcag
     3361 tggcatagaa accattaaat cactaactgg tgaagcaact acaaaaaaaa agattgacac
     3421 actattttct gacttattgc ataaaaactt ggcttatcaa aaagctgatc aaggacaaca
     3481 agctatcaaa gcagctacta aattaatcct aactattgtt atcctttggt ggggtacttt
     3541 ttttgttatg cgacaccaac tgtctttagg tcagctgtta acttataatg ctttgctcgc
     3601 ttacttcttg accccattag aaaatattat taatttacag cctaaactac aagctgccag
     3661 agtggctaat aatcgattaa atgaggttta tctagtagag tctgaatttt ctaaatctag
     3721 ggaaataact gctctagagc aactaaatgg tgatattgag tttaatcatg ttagttttaa
     3781 ctatggctat tgttctaata tacttgagga tgtttctcta acaattccac atcatcagaa
     3841 gattactatt gtaggcatga gtggttcggg gaaaacgacc ctagccaagt tgctagttgg
     3901 tttttttgag cctcaagaac agcacggtga aattcagatt aatcatcaca atatatctga
     3961 tattagtcgc acaattttac gccaatatat taattatgtt cctcaagaac ctttcatttt
     4021 ttcgggctct gtattagaaa atttattgtt aggtagccgt cctggagtaa ctcaacaaat
     4081 gattgatcaa gcttgttcct ttgctgaaat caaaactgat atagaaaatt tgcctcaagg
     4141 ttatcatact agattaagtg aaagtggatt caacttatct ggtgggcaaa aacagcggtt
     4201 atcaatagct agagcattat tgtctccggc acaatgtttc atttttgacg aatcaaccag
     4261 taatttagac accattactg aacataaaat agtctctaag ctattattaa tgaaagacaa
     4321 aacgataatt tttgtagcac atcgtctcaa tattgcgtct caaaccgata aagttgtcgt
     4381 tcttgatcat ggaaagattg ttgaacaggg atcacatcga caattgttaa atcataatgg
     4441 gtattatgca cggttaattc ataatcaaga atagcctgac aagaaccagt ctgctattga
     4501 tagactattt ttgtccgtga aatcctcgcg tatttccgtg aggagcatag tatatttagc
     4561 gatcttcaaa ttttaaaaga attgaccaaa actctatctt tccattcccc aatcgtcagc
     4621 ccgggacttc tgttttttcg gtggttccgg ctttctgtct gccacttcta tttccaaacg
     4681 cttctgctgt ttcttctgtt ccttctgttg ttctttctcc tggtggatta ggttattcac
     4741 caatggcacg atccccatcc gttttgccaa atcactcacc aaatcataag cctgtttccg
     4801 catatcccga ataaattcag cacaccgcat aatggctttt tccatgcctt ttatctgttc
     4861 tgcctgttcc ccaatgattc tattcttttg ctcaatcagc ttgtccttct ctcggatctc
     4921 ctgctgtgcc ttttgaagtt caaatgcagg aacaaagaat tcattttgga ctggaattgc
     4981 cttatttgcc tttgccaatt cagccacaag gcactgtttt tccttttcgg aatggtaata
     5041 caaatcagcc aaaacgttga agtttttgac cacattctca tgatcttttt ctagctttct
     5101 ttggctagcc aacattttgt tgtactcttc ggaagacatc ttaacggttc tgccccttaa
     5161 caattccgtc cttacttccg gttggtagat cggttcactc ttagctgcat ggtaacgttt
     5221 cggctctttt tcttgtttca cttcagaaac caacacgtcc acacgccgca catgttcttt
     5281 caccagtgct tttttgcgct ctatctcgcc ttctaaggct ttgtttctct cgacaagggt
     5341 tttgacccga tcattcacat tgttgtgaaa ttcggcaagc tgagaagcct tagaagccaa
     5401 ttcttttgtt tcctctttca cttttttggc ttcttccttc gcttccttgt attcaggaac
     5461 cgacaagtgc ttgcgctcgg attcttcttt tcccctctga atctcaaaac ccttctcctg
     5521 taagtgtttt ggcagttcgt cctgaaccgc ccttaattcc tgccggttaa aaacattttt
     5581 ggctgaaagt ttaccctcac gcatcggaac gacccctaaa tgcatatggg gcgtccgttc
     5641 atccaaatgg acctgcgcat aggcaatatt ttgctgtcca taacgttcct tgaaccaatt
     5701 tgtcgcttcc tggaagaagc gatctcgttc ctttggtgcc atgtccctaa agaattcctt
     5761 gtcgcttgta atgatccact cgttgaccag gacggcatca gaccggattg cccggtttcc
     5821 ttttttttga gaatcaatga tttccttcac gatatccgca tatttcccct gtcgatccat
     5881 caaatcatag ttcgaattcg acagttcccc gtcaatatct tcgttactgt gattcttgta
     5941 aatccgttta ttgtgccttt caattcctgc caaattattg gctttcatct tctgcattcg
     6001 agccaccaac atactcattt tgaccaccac gcttcgccca agattcggca atacttccat
     6061 gcaaagtata acccactata ctttgcggtg caaagtgtgg gctctgcgag gctctttcgg
     6121 ctgtcgccga agcacgctaa agcgtgcaga aaaccgtggc gctgccacac cgcaaggggg
     6181 ggnccccccc ttgaccccca taaaaaaact ccccccaccc ccctcacatt tgaggggggc
     6241 tccctcgccg gtcggcgggt cgaaacaaag agtttcgaca atgccaagag ggtgtaaatc
     6301 atgcgctcgt gtcaactcct taaattctcc ctcgctcgtt cctcgctcag tccgatttac
     6361 cgttgacact tcctcataat tactctttac ctaaaaaaaa gaaggacttt caggtattca
     6421 ctaagttggc ggttgtttct agaatttctg aattc
//
