LOCUS       BGC0000620             16653 bp    DNA     linear   BCT 21-DEC-2012
DEFINITION  Lactococcus lactis orf1, orf2, lnqQ, orf3, orf4, orf5, orf6, orf7,
            orf8, orf9, orf10, orf11 genes for collagen-binding protein,
            putative transcriptional regulator, Lacticin Q, membrane permease
            protein, membrane-franked domain protein, membrane-franked domain
            protein, ABC-2 type transporter, ABC transporter, ATP-binding
            protein, putative transcriptional regulator, replication protein,
            DNA integrase/recombinase, ATP/GTP binding protein, complete cds,
            strain: QU 5.
ACCESSION   BGC0000620
VERSION     BGC0000620
KEYWORDS    .
SOURCE      Lactococcus lactis
  ORGANISM  Lactococcus lactis
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Lactococcus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 20:03:36
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16653
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..16653
                     /db_xref="taxon:1358"
                     /mol_type="genomic DNA"
                     /organism="Lactococcus lactis"
                     /strain="QU 5"
     subregion       1..16653
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="RiPP"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..16653
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             993..2873
                     /codon_start=1
                     /note="orf1"
                     /product="collagen-binding protein"
                     /protein_id="BAM66971.1"
                     /transl_table=11
                     /translation="MVIASDNFINYQGSAELIKQDNEGQPLSGAVFKIVDKAGKTIQAN
                     LTSGKDGKVVVDGLAPGEYSFVETKAPTGYILNTIPVHFTILAEEEGQPSLIIASDNFV
                     NYQGSAQLIKKDSEGQPLAGAIFKVVDKNGKTVKEGLTSDKDGKVSIDDLAPGEYSFVE
                     TQAPTGYILNTIPTHFTILAESEGQPQLVVASDNFINYQGSAELIKHDINGQALSGAIF
                     KVIDADGKTIKEGLTSDETGKVLIESLAPGDYSFVETKAPEGHILNTLPVNFSISGEEE
                     GKVKVVMASDNFINYQGSAELIKHDSQGQALEGAIFKVVDSKGKIIKEDLASDKTGKVL
                     IDNLAPGDYSFVETKAPSGYILNTSKVDFTILTKEEGQPKVVMASDNFINYQGSAELIK
                     HDSQGQALEGAVFKVIDSKGKSIKENLVSDKEGKVLIENLVPGDYSFVETKAPSSYILN
                     TSKVDFTISTKEENKPKIVMASENFINYQGSAELIKVDENGKSLSGAVFNVTNSETHEV
                     VIKGIKTDANGVIKANHLKPGKYTFVETEAPAGYQLSQETRAFEIKASAENKPQVVNTG
                     KFVNKRLPITPKKPELPKTGEERNTFLPIVGVGLLMVGATLYVFFKRRKM"
     CDS             complement(3827..4402)
                     /codon_start=1
                     /note="orf2"
                     /product="putative transcriptional regulator"
                     /protein_id="BAM66972.1"
                     /transl_table=11
                     /translation="MILISDTQVRIIDAFFLLAQESECAQNITMQQIAEKAGIRRQNIY
                     KNHFHGIEDIIHTVHLIIDNNCKNLMKTFVNNNSNDLSIFLADEMLPLLYSKRAWLKNL
                     YNTSLDPDWLPFLHEQYKPLVKVYLDNNIDEICSRLKLSPEFIYKLIVGNTLVIISCWL
                     TSNNPEPPSLFKYKFLQLFSLALDDIMP"
     gene            4840..5001
                     /gene="lnqQ"
     CDS             4840..5001
                     /codon_start=1
                     /gene="lnqQ"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIi"
                     /gene_kind="biosynthetic"
                     /product="lacticin Q"
                     /protein_id="BAM66973.1"
                     /sec_met_domain="Bacteriocin_IIi (E-value: 1.1e-31,
                     bitscore: 98.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGFLKVVQLLAKYGSKAVQWAWANKGKILDWLNAGQAIDWVVSK
                     IKQILGIK"
     CDS             5078..5317
                     /codon_start=1
                     /note="orf3"
                     /product="membrane permease protein"
                     /protein_id="BAM66974.1"
                     /transl_table=11
                     /translation="MAFYLGIFFSLLLIFIVGFIFKKRIFEIFMPIISLVLSIFLFWLY
                     PDNFSIINFLLVLLLLVFVFALVGRAIYGTKRKK"
     CDS             5295..5774
                     /codon_start=1
                     /note="orf4"
                     /product="membrane-franked domain protein"
                     /protein_id="BAM66975.1"
                     /transl_table=11
                     /translation="MEQNVKNSSLYFKVSNRYVYLIVLENILGLLFIVFVFCFILVRKI
                     GGDFSSYIFIFGGILFIASMLDLLLYKRLLSIEYIIQPGRLLIKKGKFINQSTIVFTKK
                     IFAIEKVANPLNNKLCLLTVKIHLINKDIEIRGLSVEQAELMINALESQIRNNDS"
     CDS             5764..7062
                     /codon_start=1
                     /note="orf5"
                     /product="membrane-franked domain protein"
                     /protein_id="BAM66976.1"
                     /transl_table=11
                     /translation="MIHKISRLTLINEIYRQVKGIIAYSIFFKILSILFRSVSWSCYFN
                     TLVAISIILSIFTLINQLLFFFWEFDGENLIVNSGIFFKKRVVLSKGNIKGVQMVTPWY
                     FKPFKLYSLKIKLPSVGDSESIKFPVINETELMVFQTWYGDEETESIKEIGKNLVNINI
                     SRLIVSSIFTLNYLYLLTILDFLDKGLKYINISLFNILFSHYRNILFLCLIAFCGILSS
                     FIKQFLDYYYLEVYIDNHNINVRNGLLSSDYIKINLNDVIGFKISQNIGQKLLGLWSLK
                     VIVINYNITGGVSKVTHILPFSTIKEIKQFEYEIYGINTFIIEENINQSYHNIQNIALL
                     ILCIASGLSSTYWLMLVIFIFINLKILWNRKYKIDGTNLILRSSFIANSSTIIEKNNIE
                     WKEVISLFSKVNYLRIAYTYNPLKVFRCLEMRK"
     CDS             7062..7739
                     /codon_start=1
                     /note="orf6"
                     /product="ABC-2 type transporter"
                     /protein_id="BAM66977.1"
                     /transl_table=11
                     /translation="MQAIFKRELKSSIFTVKSVIILLFFLMISYWISKYSSTINQFSGE
                     KTSIISVIYGAVETFGVIFGFMMFSGTIAKIVENESIRYIIPYTTRTKLIMGKYLAMNI
                     YFLILLCLMMPVVIFVRGVNGFPILELIQAIIFFGYITSIILFLSVITKRERTANFIGI
                     ILGFIIPILGLYSVVSKNIVIRTISWLLPYRYDTLRFDSAILVILSIILIIISLKIFND
                     MEV"
     CDS             7806..8600
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 118.9; E-value:
                     4.6e-36)"
                     /gene_kind="transport"
                     /note="orf7"
                     /product="ABC transporter, ATP-binding protein"
                     /protein_id="BAM66978.1"
                     /transl_table=11
                     /translation="MDILPGKITSLVGLNGAGKSTLISLIMNFKEKDSGEVKRTTVSVM
                     PDAETMIEDMTGEQFLKFISKLKKISKEQINLIYDLADSLFIKNDLKKKIKSYSFGMKK
                     KISFIQAYIGEFDSYIFDEPTSGVDIESARIMMNHLINLKKRGKAILLTSHNIDEVQEF
                     SDYIFLLKHGEIVRKGTIEEIINKEEKPIYSLKLNISNFTELVEKYCSGVEYIVADNEV
                     EIYSNDLLKLNKIMVEMIKAGGLVISFGKEQRKLKDVIFVNE"
     CDS             complement(10192..10872)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 56.1; E-value: 9.6e-17)"
                     /gene_kind="other"
                     /note="orf8"
                     /product="putative transcriptional regulator"
                     /protein_id="BAM66979.1"
                     /transl_table=11
                     /translation="MLPDRLKELRLERGLTQQKVADRLNVSQPNYRRWETGERSPSSET
                     LKKLADFFNVSTDFLLGRYETLQPKIFYKRLVKLAKERKLTLLEVESNMGYPNNYLNSF
                     QFKEPNKKIITELSKYFSVNEDYLSGKTTINNDKQLIHYKNEVDKLFFDFKENFSDLLN
                     DLQLKEWDRLYDTETVQEYLEHLHWKINDEAKTLESRLNYYEEMVEERKHKDIPNRPEH
                     PIKK"
     CDS             12793..14124
                     /codon_start=1
                     /note="orf9"
                     /product="replication protein"
                     /protein_id="BAM66980.1"
                     /transl_table=11
                     /translation="MKKKRIKVFVFEQYFDSEFWDWDEKKSWFQNWEENKDKIFQEIYD
                     RLKFYDTPETQLKIALIVHDKDRKNNGQLIDPHVHVYVELPTKRSLELVADRIGISQHF
                     IDFANGRNKYFSFNQKAYLIHAQQPTKHQYELSEVETFGTIDYEKFILDNKDDFLKRSA
                     TVRYKEINESLDLIFDKVLFGQITYDEIMEDDSLYRLYANNEQRFISAFNSFSQYKARK
                     TLKALRNCEFKLSVVYIQGNSGIGKSHLAQEIVEKLCDESEQLGYNGVSIYSASSSNPF
                     DEYKGEEIILLDDLRPESMERADWLKVLDPMNRSRISARYRNKVIAARVIVLTNTETAE
                     SFFKNIKNEDLDQYVRRINLNVGITEKQFPRFEYDNYYNLSETKKLGEPKKERISANEF
                     LERRYGFQPVFSSDDKELFLKKLIFDELLPKSFPKDKGVIRDVS"
     CDS             14523..15650
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 103; E-value: 4.4e-31)"
                     /gene_kind="other"
                     /note="orf10"
                     /product="DNA integrase/recombinase"
                     /protein_id="BAM66981.1"
                     /transl_table=11
                     /translation="MNIMPLRVHPRGKKWEYRIKDSKGNHVVSKGGFPTEKEARIAGKE
                     AELDYLKGTRFDNNSTVFELYQKWYNLEILPSNRSVQTKIKYQRFFKKIDKYFGKLVAS
                     KIKYSQYQEIMNQIGQGVGPDYLSRLNSSIRSAVQLARRDLLNINDFTEGVRLHAQKLP
                     KNPEDKYISSLSDYQKIIDYLRSIMEYKKSVMPYLIYLMLKTGLRVGEALALTWKEVDF
                     SNKTIYTFKRIDSAKHIDSGKPKTPYSVREIPISDDLIQVLHKLHQEQEEADIIKLADG
                     LIFFDKKHGLPTNNGINKALKVYLTKLNITPLIVATGCRHTYACVLLANKVDIAVVAKN
                     LGHKNIQRIIDTYGHILQELQEVENEATRKVLQYF"
     CDS             complement(15711..16553)
                     /codon_start=1
                     /note="orf11"
                     /product="ATP/GTP binding protein"
                     /protein_id="BAM66982.1"
                     /transl_table=11
                     /translation="MCKNHLEPILALGNQIILMYDVLQAIRPSNISREVFQQLTTSFEK
                     RYLTTQFRIQTPEGKNYNSDDYVNGIKYLLYKDTGLLQYTNYDPNFSRSLFHDNSPDAY
                     FGYYDDKPLENLIDWIDEDRNYHPEHINRVLSGLVEDWKQSDGKRASITHFHEGVISRR
                     WNSTQENWVNAADDDAEDQIGSVFAVQGIDLNKVGVLIGNDLLVDSDGKLYGEPINFKN
                     VNGKHKKSELASPEVRKEFTMFVLNIYYVLLTRGIDGIRIGFXHNDSFKEYFKKTLGI"
ORIGIN
        1 cattaattac ttctgacaaa gctaatgatg tggtaactaa tcaagcccat attactggag
       61 acaacgagaa aacaatagaa caagatgttg aaaaagatgt acccgtaact aatcataacg
      121 gaagtgcaaa cggatcaaaa ggttcagtta ctttggaaaa agttggtccc ggcaaagcaa
      181 aacttgcggg agctcatctt caactttggt ctatcggtac agatggtaaa aaagataaat
      241 taattcgtga aggagatacc gacaaaaatg gtgatttaaa acttgggaat ttgcgtgtta
      301 ctgattatct tcttattgaa actaaggccc caacagggta tacacttgat gaagaactag
      361 tcaaaggtaa gaaaataaca gttgcaaaag acggagaagt ttctaatttc ccaattcaag
      421 acgttgaaaa tgaaccaacg aaagtaatct tgaaaaaagt aggactgacc attgaaaatg
      481 gtaaagaggt aaaaaatcca cttcaaggtg cataatttaa agtactagac agcaacggtc
      541 aagttgtttc aagttacgaa aaacttactt ctgacagttc tggaaatgta acgattgaaa
      601 aactaacacc tggtaaatat tcacttgttg aaaccaaagc cccagcgggt tatattttgg
      661 acccaacccc aattgacttt gagcttaaag ccaatgaaga aggaatcatc ccagatatca
      721 acttggaaaa agttaactat cagggttcag cacaactcat taaacataac agtaatggtc
      781 aagctttatc aggtgcgatt ttcaaagtta ttgataaaga tggtaataca atccaaacta
      841 atttaagctc tgataaagat ggtaaagtta aggctactgg tttatcccct ggagattatt
      901 cctttgttga aaccaaagct ccaacaggat atattttaaa tacaatacca gttcatttta
      961 caatttcagc tgaagaagaa ggtcaaccac aaatggttat tgcctcggat aattttatca
     1021 attatcaagg ttcagccgaa ttaatcaagc aagataacga aggtcagcca ctttctggtg
     1081 cagtttttaa aattgttgat aaagctggca agacaatcca agctaatttg acttctggta
     1141 aagatggtaa agtggtagtt gatggattag ccccaggaga atattccttt gttgaaacca
     1201 aagctccaac aggatatatt ctaaatacaa taccagttca ttttacaatt ttagctgaag
     1261 aagaaggtca gcctagtcta ataattgctt cggataattt cgttaactat caaggttcag
     1321 cacaattaat caaaaaagat agtgaaggtc aaccccttgc gggcgctatc ttcaaagtag
     1381 ttgataaaaa tggaaaaaca gtcaaagaag gcttgacttc cgacaaagat ggtaaagtaa
     1441 gtattgatga tttagccccc ggagaatatt cttttgttga aacacaggct ccgacaggtt
     1501 atattttaaa tacaattcct acccatttta caatcttagc tgagagtgaa ggacaacctc
     1561 aacttgttgt cgcttcagat aactttatta attatcaagg gtcagctgaa ttgattaagc
     1621 atgatatcaa cggtcaagct ttatcaggtg caatctttaa agtgattgat gcagatggaa
     1681 aaaccataaa agaaggttta acttctgatg aaactggtaa agtattaatt gaaagtttgg
     1741 ctccaggtga ctattcattt gttgagacta aagcccctga aggacatatt ttgaatactc
     1801 tgccagttaa ctttagcatc tcaggtgaag aagaaggcaa agtaaaagta gtcatggctt
     1861 cagataactt tattaattat caaggatcag ctgagttgat taaacatgac agtcaaggtc
     1921 aagctttaga aggtgcaatc tttaaagttg ttgattcaaa aggaaaaata atcaaagaag
     1981 atttggcttc cgataaaact ggtaaagtat taattgacaa tttggcacca ggagattatt
     2041 catttgttga gacaaaagct ccaagcggtt atatcttgaa tacttcaaaa gttgatttta
     2101 ctattttaac aaaagaagag ggtcaaccca aagtagtcat ggcttccgat aatttcatca
     2161 actatcaagg atctgctgaa ttaattaaac atgacagcca aggtcaagct ttagaaggcg
     2221 cagtctttaa agttattgat tcaaaaggaa agagtatcaa agagaacttg gtttctgata
     2281 aagaaggaaa agttttaatt gaaaatcttg taccaggaga ttattcattt gttgagacaa
     2341 aagctccaag tagctatatc ttgaatactt caaaagttga ttttactatt tcaacaaaag
     2401 aagagaataa accaaaaata gttatggctt cagagaactt tatcaattat caaggatctg
     2461 ctgaattaat taaggtagat gagaatggta aatctctttc aggtgcagtc tttaatgtta
     2521 ctaatagtga aactcatgaa gtagttatta agggaatcaa aactgatgca aatggagtaa
     2581 ttaaggcaaa tcatctaaaa ccaggtaaat acacttttgt tgaaacagag gctccagcag
     2641 gttatcaatt aagtcaagaa actagagctt ttgaaattaa agcaagcgca gaaaacaaac
     2701 cacaagttgt taatactgga aagttcgtca ataaaagact tccaattaca cctaaaaagc
     2761 cagaattacc taagacagga gaagaacgaa atactttctt gcctatagtt ggtgttggac
     2821 tattaatggt gggtgctact ttatatgtat tttttaaaag acgtaaaatg taaaattata
     2881 taaaaacatg gctttagcca tgtttttgat ttggaaaaag tggtagtgac ttaatacaaa
     2941 gatattttag tttgtaatac ctaaaaataa tacttcagtt tgcagtattc caataagtaa
     3001 aaaagatttg gctatattag aaccactcaa aaaaactcaa aatcatgtaa atattaagct
     3061 tggattggcc caatagagaa aattttttct tttatcatta tagtttgcaa aatggtattc
     3121 caaatgtagt cacagtaaat aaaacaatga aaaacatgtt aaatgagtta gaaattgagc
     3181 caataattac aagtgaggtg ttagataaac ttttgatagt gtactactaa gttaaggtat
     3241 cgataataaa gtagtgggaa agttaatggg cataaagata catcaatgct aataaaaata
     3301 taattaaaag aatatgataa aataataaaa ccttgtatat caacgataca aggtttttta
     3361 tctatgccga gtgcaagaag tggcattata aaataataat cttttagttt aataatagta
     3421 ttttagatga tgttataaat ttatatttgc tgaaagaaca agtataaatt tataaaaaaa
     3481 taaaaaagtt ataagaaaag ttataaaatt tactttaaga ggattataga aattgggtta
     3541 ttaaattcga cggatttcga gaattatgga atggttttat ttagaacgaa taagaaggaa
     3601 aatcacatta aataagcagt ttatcttgtg taatattttt tataatctat aaagtgataa
     3661 aaattggaca ctttatggac acttaatttt atagaataaa gggctactaa aaactgatta
     3721 gtaacctttt attttgtaaa ttcttatgat ataaaaatga agtacattct gctatttatc
     3781 tgtttatctt tcgtcaaact atagcataat atgtttaaaa ttaatattaa ggcattatat
     3841 catctaatgc taaagagaag agctgtaaaa atttgtactt aaaaaggcta ggaggttcgg
     3901 gattattgct cgtaagccaa caagaaataa ttacaagagt atttccaaca attaatttat
     3961 atataaattc aggactaagt ttcaatcttg aacatatttc atcaatatta ttgtctagat
     4021 atactttgac caacggctta tattgctcat gtaaaaaagg tagccaatcg ggatctaatg
     4081 aagtattata taaatttttt aaccaagctc ttttgctata aagcagtggg agcatctcat
     4141 cagctaaaaa tattgaaaga tcattagaat tattattaac aaatgttttc atcaagtttt
     4201 tacaattatt atcaattata agatgtaccg tatgaataat atcttcaatt ccatgaaaat
     4261 ggtttttgta aatattctgt cttcgaatac cagctttttc agcaatttgt tgcatagtta
     4321 tattctgagc acattcactt tcctgagcaa gcaagaaaaa agcatcaata attctcactt
     4381 gagtatcact tattaatatc atataaatct ccttattaaa atatcccagt tcaattataa
     4441 caaaaataca tataaatgcc gtaatatctc taaaaaagtt acatgatgtc acttaataaa
     4501 cagaggaaac tactgtttta agttatggtt aaggtcattt gaatgacaac ccgacacctt
     4561 ttaatagtac tatacaaata ataaatatga taacattatc tatgtaagat aaagcttcta
     4621 tttatacttg aaccacatct atgacgatag aaaaaggctg atcagctaat caattataaa
     4681 aataaatatt atcttatatt ttatgatcat ggacataaaa aaagtagtgc taaaatggtt
     4741 tagcactacc ttcactgaaa attcattata tcaataatat ttaataaagt aaagaataat
     4801 gattgtataa tgattgttgc aaagagaaag cgtgttaaaa tggcagggtt tttaaaagta
     4861 gttcaattac tagctaaata tggttctaaa gctgtacaat gggcttgggc aaacaagggt
     4921 aagattttag attggcttaa tgcaggtcag gctattgatt gggtagtttc gaaaattaag
     4981 caaattttag gtattaagta attttttgat catttagagt taatcttata taaggttaat
     5041 tctaaatgat tttgttattt ttttaaggag tgttattatg gcgttttatt tagggatttt
     5101 tttctcatta ttattaatat ttattgttgg atttattttt aaaaaaagaa tttttgaaat
     5161 ttttatgcca ataatctcac tagtattatc gattttctta ttttggctgt atcctgataa
     5221 ttttagtata ataaattttt tattagtttt gctactacta gtttttgttt ttgcattggt
     5281 agggagagcg atttatggaa caaaacgtaa aaaatagtag tttatatttc aaggtttcaa
     5341 atcgttatgt atatttaatt gttttagaaa atattttagg tttattgttt attgtttttg
     5401 tattttgctt tatactagta cgaaaaattg gcggagattt ttcttcatac atttttatct
     5461 ttggtgggat attattcatc gcttcaatgt tagacctttt gctatataag cgtcttttaa
     5521 gtattgagta tattatacaa ccaggaagac tgctcatcaa aaaaggaaaa tttataaatc
     5581 aaagtacaat tgtctttaca aaaaaaatat ttgcaattga aaaagtagct aatccattaa
     5641 ataataaact ttgcttacta accgttaaaa tacatctaat aaacaaagat atagaaatac
     5701 gtggtcttag cgtagagcaa gcagagttaa tgataaatgc tttggaaagt caaataagaa
     5761 ataatgattc ataaaatatc gagactaact ttaataaatg agatctatcg tcaagtaaaa
     5821 ggaattatag catatagtat attttttaaa attttatcta ttttatttcg ttctgtttct
     5881 tggagttgtt attttaacac tcttgttgct atatcaatta tattatcaat ttttacactt
     5941 attaatcaat tgctgttctt tttctgggaa tttgacggtg aaaatctgat agtaaacagt
     6001 ggcatatttt tcaaaaaaag agttgtttta tctaaaggta atattaaagg ggtacagatg
     6061 gtaacaccat ggtattttaa accgtttaaa ctctactccc ttaaaataaa attaccttca
     6121 gtaggagatt cagaaagtat aaagtttcct gttattaatg aaacagaact tatggtattt
     6181 cagacgtggt atggcgatga agagacagaa agtataaaag aaataggaaa aaacttagta
     6241 aatataaata ttagtcgttt aattgtgagt tcaattttta cgctaaacta tttgtatcta
     6301 ttaactattc tggatttctt agataagggt ctaaagtata ttaatataag cttgtttaac
     6361 atattatttt ctcactatag aaatatacta tttttatgtt taatagcttt ttgtggaatt
     6421 ttatcatctt ttataaaaca gttcctagac tattattatc ttgaagttta tatagataac
     6481 cataatataa atgtgcggaa tggtttacta tctagcgact atattaaaat taatctcaat
     6541 gatgttattg gttttaaaat aagtcaaaat ataggtcaga aactattagg tttgtggtca
     6601 ttaaaagtga tagttataaa ttataatatc actggtggag tatctaaggt aactcatatt
     6661 ttaccctttt caactattaa agaaatcaaa caattcgagt atgaaatata tggtataaat
     6721 acttttatta tagaagaaaa tataaatcaa tcgtatcata atatacagaa tatagcgttg
     6781 ttaatactat gcatagcttc agggctttca tcaacatatt ggttaatgct cgttatattt
     6841 atatttatta acttaaaaat attgtggaac agaaagtata aaattgatgg tacaaattta
     6901 attcttagaa gctcttttat tgctaacagc agtacaataa ttgaaaaaaa taatatagaa
     6961 tggaaagaag taattagcct attttcaaaa gttaattatt taagaattgc ctatacctat
     7021 aatcctttaa aggtattcag gtgtttagaa atgaggaaat aatgcaagca atttttaaaa
     7081 gggagttgaa gagctctatt tttacagtaa aatcagttat tattttattg ttctttttga
     7141 tgatatcata ctggattagt aaatattcat ctacaattaa ccaattttct ggggaaaaaa
     7201 cttcaattat atcagttatc tatggagcgg ttgagacatt tggtgtaatc tttggtttta
     7261 tgatgttttc gggcacaatt gcgaagatag tagagaatga atctattaga tatattattc
     7321 cttatacaac aagaacaaaa ttgattatgg gaaaatattt ggctatgaat atatattttc
     7381 taatattact ctgtttaatg atgccagtgg ttatatttgt acggggagta aatggttttc
     7441 caattttaga attgattcaa gcaattatat tttttgggta cataacgtca attatacttt
     7501 tcttatcagt cattactaaa cgagaaagaa ctgcgaattt tataggaata attctagggt
     7561 ttataattcc tattttaggt ttatattctg tagtttccaa aaatatagtc attcgtacta
     7621 tttcttggtt acttccatat cggtatgata ctctcagatt tgattcagcc attttagtaa
     7681 ttctttctat aattttaatc ataatatcat taaagatatt taatgacatg gaggtataga
     7741 gtgtgataaa agttgaaaat gtttccaaaa gttttaaaaa caatctagtt ctaaaaaatg
     7801 tcaatatgga tatactacca ggaaaaataa cttcgctggt tggtttgaat ggtgctggta
     7861 aatctacatt gatttcatta attatgaact ttaaagaaaa agatagtgga gaagtaaaga
     7921 gaacaactgt ctcagttatg ccagatgccg aaacaatgat agaggatatg actggggaac
     7981 aatttttaaa atttatatca aaacttaaaa aaattagtaa agaacagatt aatttgattt
     8041 acgatttagc agattcatta tttataaaaa atgacttaaa aaagaaaata aaaagttatt
     8101 cttttggtat gaaaaaaaag atttcattta ttcaagctta tattggagaa tttgattcat
     8161 atatttttga tgaacccact agcggtgtag atatagaatc tgcacgaatt atgatgaacc
     8221 atcttatcaa tttaaaaaaa cgagggaagg ctattttact cacaagtcat aatattgatg
     8281 aagttcaaga atttagtgat tacatttttt tactcaaaca cggggaaatt gtaagaaaag
     8341 gaactataga ggaaataatc aataaggagg aaaagcctat ttatagtttg aaattaaata
     8401 ttagtaattt tacagaatta gttgaaaaat attgtagcgg agtagagtac atagttgctg
     8461 ataatgaagt ggaaatttat tccaatgatt tgttaaaact taataaaata atggttgaaa
     8521 tgataaaagc tggaggacta gttattagtt ttgggaaaga gcaaagaaag ttgaaagatg
     8581 tgatttttgt aaacgaataa tttcattaga aaaaatgatt acaacgaata aattcgatta
     8641 aaaataaaaa acaccttata aactttataa ggtgttttgt ttaataaagg cataagagat
     8701 taaaaaatat aataatattt atttagtgaa ccaatagtat ttcaagaatt atgaaatagt
     8761 tttacttagt atgagaaaga gggaaaattg cattaaataa gcagtttatc tcgtgcaata
     8821 ttttttacaa tctatagagt gctgaaaata ggacacttta tggacactaa atttataaaa
     8881 gaaagggcta ctaaggaact caatagtaac cttttctttt ataaattcat ctcttagttg
     8941 aggagcgtta tgcttgaaca taactattta aaaagttcta aaactctaaa gaccacgttt
     9001 tttctaattt attttaaata attttttcaa ttcttttgac ttattatcag atttagaata
     9061 gattgtgtag gcttgtgtac aaaggtcttt tgttcacttt cagcaggata attaacaatt
     9121 atgtccatat aaatagtaaa atattttgca cgccagtcat taaacataat atgttggtca
     9181 tcagtatcag ttttagagag tattaatatc gacaagaaaa cccaaaaatc ctttaagaaa
     9241 tcttgtttat ttagtgattt tgaaattgtg tatgtttgaa taaataattc ttggcaattt
     9301 gaatctgtac aatttgtttc tgatctccct ttaagtcgta ataataatcg aagtatcccc
     9361 agttttttag tcttttcttc aaagctggag atgcgtattt aaaatcaaca agcatcgctc
     9421 taatatactt atcaagctgt aaatcaaaac tttcaagagt taatttttga ttatgtccag
     9481 aaggtacaac aagataatta agatagtatg aaaaaggata ataatatttt aaaataaaat
     9541 tattgtagac ttcttcttca gttttaattt tatctttatc cttttcgttt tctttttcta
     9601 tatataaaac aaaaaataca ccaatcacac cgattattgc tcataaataa ttactccaaa
     9661 aggagaacca atcggaagcg ttaccaaagg ttccaaagtt tggaatatat ttaaccagaa
     9721 agcctacaag caaaggtaga gcaaaaatta ttaatatgaa aattgcaatt tttgagttgt
     9781 tatttttgag ctttttaatc atgattattt tatcctattt ttttatattt tgggttctat
     9841 ttttaacact tttatataat tatatcattt gtaatatagc aatagaaaat gtaaaaaaaa
     9901 tcgaggttat aagaatatga taaaaaaagt aaaaaaataa agaaaaagcc ttacatatca
     9961 acgatagaag gcttttaact tagtgccgag tgcagactta attatggatt tttatccttt
    10021 attttaatag caaaccgcaa taaagtaata tttaatatgc tttaattttt gcaactttgt
    10081 ttaagtctgg gcacaaaaaa aggcacaaaa aattataaat taattcgtga aaatgaagaa
    10141 acgtgtttct gaaattggag acgaattcta gctgataact ttgttgtcag cttatttttt
    10201 tattggatgc tctggacgat taggtatgtc tttatgtttt ctttcttcca ccatctcttc
    10261 ataatagttt aatctagatt caagtgtttt agcctcgtca ttaattttcc aatgaaggtg
    10321 ctctaaatac tcttgaactg tttcggtatc atatagcctg tcccattctt ttaattgaag
    10381 gtcatttaaa aggtcggaaa agttctcttt aaaatcaaaa aatagtttgt ctacttcatt
    10441 tttataatga ataagctgtt tatcattgtt aatcgtagtt tttccgctta ggtaatcttc
    10501 attaaccgag aagtattttg aaagttcggt gattattttt ttatttggtt ctttaaattg
    10561 aaatgagttt aagtagttat taggataacc catgttgctt tcaacttcca agagtgtcaa
    10621 ttttctttct tttgctaatt tgactaaacg cttataaaaa attttcggtt gcaaggtttc
    10681 gtaccttcct agcagaaaat ctgtgcttac attaaaaaaa tcagcaagtt tttttaaggt
    10741 ttcgctacta ggggaacgct ctcctgtctc ccatctacga tagttaggct gtgaaacatt
    10801 caacctatca gctacttttt gttgagttag tcctcgttct agtcttaatt cttttaacct
    10861 atcaggaagc attttaaatc ctcttattaa tttttttgtt tgacaatata tccaaatagg
    10921 tatataattt atttatacct atttggatat taaatgtgta ttgaagttct ttaggtatat
    10981 tataacataa ggaggattgc ctataaatca aataaaataa aaaagctctt tccacgacca
    11041 agaagaaaga agcttagtaa atttaacagc ttaattataa cacaaaattg aaaatgaggg
    11101 aaaacatgga aaatcaagaa aataaagttg aattagatga tttaatcaga ggactgggaa
    11161 ttatctcaaa tgtcatgtta atgggacgac ttctcccaac agaagcgagt gatttgaaag
    11221 atgtatctaa cgaacaaatg attatgaatt acaataatct ttgtgaaatg acagaagttt
    11281 atacagacca tttaattagt ggactttcag aagttgagaa aaactggcgt actgataatg
    11341 ttgacgcaag taaatttcga aaaattgaag ctgtcattaa agctggatga attatcgaga
    11401 gcttgctgaa gcgatagacc gtccttataa tacagttcgt aaatggcgtg gagaaattac
    11461 taagatttca ggaaacgaat ttaagcgaat taaagtaaga aatggtcgag gacgaaaaaa
    11521 cagaaccact tatgattttg acgaactaga tgtgaaatgc tttaaagagc tgaatagatt
    11581 gctaaaaact ggaaaaaata aagttgaagc aattcatgaa gtctttggaa ataaagaagt
    11641 cgaagaactt caaaagcaaa ataatgattt tgatagtcta gaacgaaaaa gtcaagcatt
    11701 aagaggacaa attaaagcac tttctaagag aatacaagac caaaagagtg agcttgatac
    11761 catgaaaata aagacaagtg acctaacaga acgaattgaa aacctcgaaa aaagaggaat
    11821 aaaaaatata tttaataaga aataaatgga gaaaaaatat gaacgtattt agcttgaaag
    11881 atgaacaacc aaacttatcc gcagtagaat tgaatgtcaa tcaatttgaa gttcctaaac
    11941 aatttttagc tgatttttca aaagctcgtc ataattttgt ttatgaaaaa gggcacaaaa
    12001 cagataaaat ttcaaaagca acattgatta ctattgcaaa agatgaagca gataaactgg
    12061 caagtgttgg gttagatgtc aaagaatata tgaaacttcc tgtagaaatt gaagattaca
    12121 agagtattga cgctctcatg gatagtgaag aaatgcttgc ggttgagttg gtagatgtcc
    12181 gcgtgaagtt caaagtggat aatttccgtg cggttggtta taaattgatt gcgcggtcgt
    12241 tgaaagtaat cgaggacaca aaagcgcctg ttaagcctga caaataataa aactgactaa
    12301 caaataaaac ctgttttaga gagtgcgttg aggtctgact acgtagcctg tcgccctcaa
    12361 ggcgataagg gcgagtagtc agaagctctg ctaacaaggc gctctcggaa aaaaacaggt
    12421 tttattttgt tagagataaa ttatattatc tgataatgga cgtaaaagtg caagagtttc
    12481 tgggaatatg tgtactgtga gccacatcct acgcccgcac cgttttaggg cttgtcaaca
    12541 aaaacggtgt aaacccccac tagcgctagc tttaggttag acacccccca cctaactaaa
    12601 agccgaaaat tgctaaaaat tagtggttaa aggtggctat caagggtggc taacaagagt
    12661 tgtgagccat tttaccccta ttttttagag ttgtgagcca ccaatattta aaaaaataac
    12721 ccaaaaaagc tgaaattagt gtaaaagctt ttaaagatta aaaataatta ataattatag
    12781 aaagaagaaa atatgaaaaa aaagcggata aaggtctttg tttttgaaca atattttgat
    12841 tcagaatttt gggattggga cgaaaaaaag tcttggtttc aaaattggga agaaaataaa
    12901 gataaaattt ttcaagaaat ttatgaccga ttaaaattct atgatactcc tgaaacacaa
    12961 ttaaaaattg ctttaattgt tcatgataaa gatagaaaaa ataatggtca gttgattgac
    13021 cctcatgtcc atgtatatgt agaattacct acaaaacgtt cacttgaatt ggttgctgat
    13081 agaataggga tttctcaaca ttttattgat tttgcaaatg gaagaaataa atacttttct
    13141 tttaatcaaa aagcctatct tatccatgcg caacaaccta ctaaacatca gtatgagctt
    13201 agtgaagttg aaacttttgg aacaatagat tatgaaaagt tcattttgga taataaagat
    13261 gactttctaa aacggagtgc aactgtacgt tataaagaaa tcaatgagag tttagacctt
    13321 atctttgata aagttctctt tgggcaaatt acctatgatg aaatcatgga agatgacagc
    13381 ttatatcggc tatatgcgaa caatgagcaa cgctttattt cagcttttaa ttctttctca
    13441 caatataaag cacgtaagac attaaaagcc ttgcgaaatt gtgaatttaa gttgagtgtg
    13501 gtgtatattc aaggaaattc agggatagga aaatcacatc ttgctcaaga aattgtagaa
    13561 aaattatgtg atgaatcaga acaattaggg tataacggag tttctatcta ttcagcttca
    13621 tcatctaacc cttttgatga atacaaggga gaagaaatca ttttacttga tgaccttaga
    13681 cctgaatcga tggaacgtgc agactggtta aaagttttag accctatgaa tcgttcaaga
    13741 atctcggcta gatatcggaa taaagtgatt gcggctcgcg tgattgtatt gacaaatact
    13801 gaaacagcag aatctttctt taaaaatatt aaaaatgaag atttagacca gtacgttcgc
    13861 agaatcaatt taaatgttgg aattactgaa aaacaatttc ctcgatttga atacgataat
    13921 tattataact tatccgaaac aaagaaatta ggtgaaccta agaaagagcg aatttcagca
    13981 aatgaatttt tagagcgtag atatggcttt cagccagtat tctcatcaga tgataaagaa
    14041 ttgttcttaa agaaattaat ttttgatgaa ttgttgccta agagttttcc taaggacaaa
    14101 ggagtgataa gagatgtatc ttaagaaagt agatagtcaa aaagctaaga tgttcgctga
    14161 tataatgcct tttgcctacg gtacgtgata tagaaaaatg aatagtaatg gtacagtagc
    14221 gacaaattta aatggtcaag cactttatac ctttatgaat caagaagatt tgcaagactc
    14281 attaaaaaat aaagaattta cacgtgtaga attttaaaac gaaaaggaaa taaatatgaa
    14341 tattataacg aaagatgaaa ttattgaaca aacaggaatg actaaatctg tggcttctag
    14401 gattattcga gaaggtaaac aggaaatggt taaaaaaggc tatccttttt acaataataa
    14461 gagattgaat ttttgccctt tagaagtagt aaataagatg cttgggttgg aattgaaagg
    14521 aaatgaatat catgccatta agagtgcatc ctagagggaa aaaatgggaa tatagaataa
    14581 aagatagtaa aggaaatcat gtagttagta aagggggatt tcctaccgaa aaagaagcta
    14641 gaatagctgg taaggaagct gaactagatt atctaaaagg aacaagattt gataataatt
    14701 ctacagtttt tgaactttac caaaaatggt acaacttgga gattcttccg tctaacagaa
    14761 gtgttcaaac taaaataaag tatcaaagat tctttaaaaa aattgataaa tattttggaa
    14821 aactagtagc aagtaaaatc aaatatagtc aatatcagga aataatgaat caaataggtc
    14881 aaggtgtagg gccagactat ctatctcggc taaattctag cattagaagt gcagtacaac
    14941 ttgctagaag ggatttactt aatataaatg attttactga aggggtgaga ttacatgcac
    15001 aaaaactccc aaaaaatcca gaggataaat atatttcgag tttatcagat tatcaaaaaa
    15061 taattgatta tttaaggtca ataatggaat ataaaaaaag tgttatgcca tatcttatct
    15121 atttaatgct gaaaacaggg ctaagggttg gagaggcatt agcacttaca tggaaggaag
    15181 tagatttttc taataaaact atttacacat ttaaaagaat tgatagtgct aaacatattg
    15241 attcaggaaa acctaaaact ccatattctg ttcgagaaat tcctataagt gatgacttaa
    15301 tccaagtctt acacaaactt catcaggagc aagaagaagc tgacattata aaattagctg
    15361 atggactgat attttttgat aagaaacatg gattaccaac aaataatggc ataaataaag
    15421 cattaaaagt atatcttaca aaattaaata tcactccttt aatagttgca actggatgtc
    15481 gacacactta tgcgtgtgtt ttattggcaa ataaagtaga tatagcagtt gtggcaaaaa
    15541 atttaggtca taaaaatata caaaggatta ttgatacata cggacatata ttgcaagaat
    15601 tacaagaagt cgagaatgag gctacaagga aagtgctgca gtatttttaa tatacattac
    15661 tagtttaaaa gttcctcaaa aatttattaa ttaagtttat ataatggaat ttaaatgccc
    15721 aatgttttct tgaaatactc tttnaaagaa tcgttgtgnc aaaagccaat ccgaatacca
    15781 tctatacccc tagttaatag aacatagtat atgtttaata caaacattgt gaattcttta
    15841 cgcacttcag gtgacgcaag ttcggatttt ttatgttttc cattcacatt tttaaaatta
    15901 attggttcac catataattt accatcactg tcaactaata aatcattgcc tattaggact
    15961 ccaactttat ttaagtctat tccttgtact gcaaatactg aaccaatttg atcttcagca
    16021 tcatcatcag ctgcgttaac ccaattttct tgtgtagaat tccaccttcg agaaattaca
    16081 ccttcatgaa aatgcgttat agatgctctt tttccatctg attgtttcca gtcttcaaca
    16141 agacctgaaa gtacacgatt tatgtgctct gggtggtaat ttctatcttc atcaatccaa
    16201 tctatcaaat tttcaagtgg tttatcatca taataaccaa aataagcatc tggactatta
    16261 tcgtggaaaa gtgaacgact aaaattagga tcataattag tatattgaag cagtccagta
    16321 tctttatata aaagatactt aattccattc acataatcgt cagaattata attcttacct
    16381 tcaggagttt gtattctaaa ttgagtagtc aaatatcgtt tttcaaagct agttgtcaat
    16441 tgttggaata cttctctgga aatatttgat gggcgaatag cttgtaagac atcatacatt
    16501 aaaataattt gatttccgag tgctaaaata ggttctagat gatttttgca catagaaaat
    16561 tcagtatttt tatatattgt attgaatgca ctgtgctgtt tagaaccttt tcgtgataat
    16621 ctatgagatt catcaacgac tataatatcg tag
//
