LOCUS       BGC0000640              8814 bp    DNA     linear   BCT 06-DEC-2005
DEFINITION  Enterobacteriaceae bacterium DC404 carotenoid synthesis gene
            cluster, complete sequence.
ACCESSION   BGC0000640
VERSION     BGC0000640
KEYWORDS    .
SOURCE      Enterobacteriaceae bacterium DC404
  ORGANISM  Enterobacteriaceae bacterium DC404
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 20:06:51
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8814
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..8814
                     /db_xref="taxon:338905"
                     /mol_type="genomic DNA"
                     /organism="Enterobacteriaceae bacterium DC404"
                     /strain="DC404"
     protocluster    1..8814
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[4423:7994]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4424..7994
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..8814
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..8814
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000640"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..8814
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            2400..3305
                     /gene="crtE"
     CDS             2400..3305
                     /codon_start=1
                     /function="converts farnesyl pyrophosphate (FPP) to
                     geranylgeranyl pyrophosphate (GGPP)"
                     /gene="crtE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 176.5; E-value:
                     1.1e-53)"
                     /gene_kind="biosynthetic-additional"
                     /note="GGPP synthase"
                     /product="geranylgeranyl pyrophosphate synthase"
                     /protein_id="AAZ73133.1"
                     /transl_table=11
                     /translation="MTRPFETHPGHDGELHELHAALQRRLDELLPVGDERDRVSSAMRE
                     GVLAPGKRIRPLLLILAARDLGCDRDHPGLLDMACAVEMVHASSLILDDIPCMDNAALR
                     RGRPTIHRQYGEDVAILAAVALLSSAFGVMVAAQGLSPECRSQAVAELSMAVGTQGLVQ
                     GQYKDLREGTAPRSAEEIATTNELKTSVLFGATLQIAALAAGASPAARQKMRCFAQDLG
                     QAFQLLDDLADGHAGTGKDINKDAGKSTLVAMLGSDAVRERLDTHLRRADAHFSRACGK
                     NQATRRFMHAWFSKQLAAFS"
     misc_feature    2400..8466
                     /note="carotenoid synthesis gene cluster"
     gene            3343..4392
                     /gene="idi"
     CDS             3343..4392
                     /codon_start=1
                     /function="catalyzes the isomerization reaction from
                     isopentenyl pyrophosphate isomerase (IPP) to dimethylallyl
                     diphosphate (DMAPP)"
                     /gene="idi"
                     /note="IPP isomerase"
                     /product="isopentenyl pyrophosphate isomerase"
                     /protein_id="AAZ73134.1"
                     /transl_table=11
                     /translation="MKDAHLVQRKNDHLDIVLHPDRAMSTIRTGFDAWRFEHCALPELD
                     LDGIDLSTTLFSRPLKAPVLISSMTGGAARARDINRHLAQAAQTLGLAMGVGSQRVALE
                     DGAQHGLDAQLRHIAPDVPLLANLGAAQIRGAQGLDYARRAVDMIDADALIVHLNPLQE
                     ALQGGGDRDWRGILNAIAQLVRDLPVPVVVKEVGAGISPDVACRLADVGVAMIDIAGAG
                     GTSWAAVEAERAPTPEARNVAMAFADWGIPTADALRRVHLALPDIPLIASGGIANGIDA
                     AKAIALGADLVGQAAAVLAHANASGDAAIAHFRTLITQLRIACFCTGSANLQALRHATL
                     LPVNGGASL"
     gene            4424..5593
                     /gene="crtY"
     CDS             4424..5593
                     /codon_start=1
                     /function="catalyzes the terminal cyclization reaction from
                     lycopene to beta-carotene"
                     /gene="crtY"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /product="lycopene cyclase"
                     /protein_id="AAZ73135.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 1e-127, bitscore:
                     414.9, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKWDLILVGAGLANGLIAWRLKQRHPTLAVLMLECGDAPGGNHT
                     WSFHQHDITPAQHAWLAPLVAHRWDGYDVHFPNVSRTLHDGYLTITSTRFAQAMRGLMK
                     ENLLTNVTVSRVSGQEVTLSDGRRFTAGAVIDGRGYQPSPHLSIGYQAFIGQEWQLTAP
                     HGLTRPILMDARVAQGNGYRFVYTLPLSADTLLIEDTHYIDGPTLDADSARARIADYAR
                     QQGWQLARLVREEQGALPITLSGDPAAFWHQFHHQPVSGLRAGLFHATTGYSLPLAVRL
                     ADRIANAPGLHQGALYQLIADFAARHWQTQRFFRLLNRMLFLAGTPDQRWRVMQRFYQL
                     DEQLIARFYAGQLRSADRARLLLGKPPVPIVGAIKALLHTHSSLRAHHK"
     gene            5590..7068
                     /gene="crtI"
     CDS             5590..7068
                     /codon_start=1
                     /function="desaturates phytoene to lycopene"
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 442.1; E-value: 5.1e-134)"
                     /gene_kind="biosynthetic-additional"
                     /product="phytoene desaturase"
                     /protein_id="AAZ73136.1"
                     /transl_table=11
                     /translation="MKQTIVIGAGFGGLALAIRLQAAGIPTTLLESRDKPGGRAYVYED
                     RGFTFDAGPTVITDPSAIEELFTLAGKRLKDYVELMPVTPFYRLCWEDGKVFDYANDQA
                     ALESQIAAFNPNDVAGYHRFLDYSRAVFAEGYLKLGAVPFLSFRDMLRAGPQLARLQAW
                     RSVYDKVSAYVEDEHLRQAFSFHSLLVGGNPFSTSSIYTLIHALEREWGVWFPRGGTGA
                     LVQGMVKLFQDLGGTLTLNAQVERLETVDNQVKAVHLVNGQRLEAAAVASNADVVNTYA
                     RLLGHHPHGAATAKKLKRKRMSNSLFVLYFGLDHHHTQLAHHTVCFGPRYKALIDEIFS
                     ADTLSEDFSLYLHAPCVTDPSLAPPGCGSYYVLAPVPHLGNAPLDWSVEGPRLRDRIFD
                     YLEARYMPGLRSQLVTHRMFTPEDFRDTLDAWQGSAFSLEPILTQSAWFRPHNRDSVVD
                     NLYLVGAGTHPGAGVPGVIGSAKATAQLMLKDLA"
     gene            7068..7994
                     /gene="crtB"
     CDS             7068..7994
                     /codon_start=1
                     /function="converts two molecules of geranylgeranyl
                     pyrophosphate (GGPP) to phytoene"
                     /gene="crtB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /product="phytoene synthase"
                     /protein_id="AAZ73137.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.7e-49, bitscore:
                     155.7, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQPLLEHASATMTAGSKSFATASKLFDKRTRRSALMLYTWCRYC
                     DDVIDGQVVGFAAPTEQSDTPEARLQRLRKMTRRAYDGETMQEPPFAAFQEVALAHAIP
                     PTQAFDHLEGYAMDVRNERYYSLDDTLRYCYHVAGVVGLMMARVMGVRDEATLDRACDL
                     GIAFQLTNIARDIVDDAQVGRCYLPQQWLAEVGLNEQTCTVRANRPALARLAARLVTEA
                     EPYYQSALAGLGDLPLRSAWAIATAHGVYREIGVKVLMAGEKAWDTRQGTTRAEKLALV
                     ISGAKQAMASRKASWPPRDPHLWQRPR"
     gene            complement(7909..8466)
                     /gene="crtZ"
     CDS             complement(7909..8466)
                     /codon_start=1
                     /function="catalyzes the hydroxylation reaction from
                     beta-carotene to zeaxanthin"
                     /gene="crtZ"
                     /product="beta-carotene hydroxylase"
                     /protein_id="AAZ73138.1"
                     /transl_table=11
                     /translation="MLALWNTGIVLLTIIIMEGVATFAHKYIMHGWGWGWHHSHHTPRK
                     GAFERNDLYAVVFALLAIALIYAGSEGYWPLQWIGAGMTGYGVIYFIVHDGLVHQRWPF
                     RYVPRRGYLRRLYMAHRLHHAVRGREGCVSFGFIYAPPVDKLQAVLRERNGRPASAGAA
                     RGADRAAASSPSGKPSPASRRK"
ORIGIN
        1 accgcgaaga cagcaacgtg ctggagaccc gctttgagac ggaaccgggt cggtgctgat
       61 caccgagtcg ctgaacagca cgcttgctgg ccggctgccg tggagcgaac tggcccgccg
      121 catcgacggt attgagggcc acgtgacgct gaacgtcagc ctgcgtttcg gtaccgctgc
      181 cgagacgcgc tccccgtgga gggcgaacac ctttaagggc gatgtgtttc acattgccga
      241 tctgatggcg atgctgcgca ccagcgaaga cattgagatt acccactgcg acgatgaaaa
      301 aattaccgcc cagctgatga cctcaccggg gtcgcgctcg ctggtcgccc tgctggtcac
      361 cgagaaagag ccgctggcgg tgccggatct ctccgccatc gatgaccgca tcgaaaccag
      421 ccaccttgcc tggtgcgact ggacccgcag cctcagctac cgcggtctct acgacaagca
      481 cgtcaaacga tccgcgctgg cgctgaagtt tctctggtac tccccgaccg gcgcgctggc
      541 ggcggcggcc accacctcgc tgccggaagg cattggcggg gagaaaaact acgactaccg
      601 ctatgcctgg gtgcgcgatg cctgtctgat catcaaagcg ttcgtgttcc tcggtgcgct
      661 ggaggactgc aaagccgcct tctcctggct gtcgaaaacc attattcgcc acgggcctga
      721 gctgcgcgcc tgctatacgc tcgaaggtga cgaggtgccg gccgagtact atccgccgct
      781 gcgcggatat cgggattccc gcccggtgcg ggtgggcaac aacgcccgca accagatcca
      841 gctcagcatg tacggcgaca tgctcgccac cgcgcagctg tttatcgagg cgggacacgt
      901 actggatctc gccacctcgc gcctgcttgg cgaactggcg aactgctgcg ccgacagctg
      961 gcggcagaag gactccggca tctgggagtt accggacgag cagcactata cccactcgaa
     1021 gatggcctgc tggctggcac tggatcgcgc cgtggcgatg gcagaacaga agcacatcga
     1081 accgacctgg gtcgggcgct ggcagcgcga gcgcgatcgg atccgcgact ggatcgaaac
     1141 ccactgctgg tcggagaaaa agcaggccta cgtgttttac gtcggggacg acgagcggct
     1201 ggatgccgcg ctggcgctgg tgcacgacta cggcaacagc gtaaacccgc agcgtatgct
     1261 ggccacctat cgcgccatca aagcggagct gggacacgac acgcccatgc tctaccgcta
     1321 cagcgaggtg gaaaaggaag aaagcacctt tgtcgcctgc tcgttctggc tggtggaagc
     1381 cctcgccgcg atgggtgaaa ccgacgaggc ccaggcggcc atgaccggca tcctcgagag
     1441 gctctgcgac cggggcaatg ttgaaacttt taacgagatg tttgatgtgc gtaccgacga
     1501 gtggcgcggc aaccttcctc aggggctgag ccatctggcg ctgatctgcg ccgcgcaggc
     1561 gctttcggaa aaatgccgca acacgcgcga ctgacgcacg cgtagctaag gagaagacga
     1621 tgaccatcag aggtatcgaa catattggta ttaccgtcgc cgacctcacc ggggcggagc
     1681 ggtttttcat cgaggcgctg gatgccagcg tgctctaccg catcgtgccg cccggcgcgg
     1741 cggacaatgc catcagcggc gaccagatga cgcggctcaa tggctttccc ccggagatgc
     1801 gggttaccgg cctggccatg ctgcgtctcg gcaacggctg caatattgag ctgtttgaga
     1861 tcgatcccgg cgtggcagac gcgcccggaa atatcagcca ggcgggcctg aaccacctgt
     1921 cggtttacgt ggacgacatt cagcaggccg gcgcacgggt aaaagcacag ggcgccacgc
     1981 tgtttgacgg gccgagcgac tgctttgctc aggaagaggg ccgcggcaac cagacctggt
     2041 tctgccgcac gccttttggc ctgctgattg aactcatctc ccttccctcg ccgcttcgct
     2101 acgatgcgca ggcgcagcaa acccgctgga tcccccagcg ctgacaggcc tctctcacgc
     2161 gggcatcgcc cgcgttgtca taccctcgtc accgtcctga caaaaattaa caataaattt
     2221 tcatttttca gccagacttt aagcacatag cgtcgccatg acatttattt tcatctaaac
     2281 ctatacaaga aaaacattga tgtataactt tgcataccgc tgcacacagg ctcagactgc
     2341 gacacccgtt gcgggtcagc gctatttcca tttcatctgc gagacgccgg gtaccaacca
     2401 tgacaagacc ctttgaaaca catcccggtc acgacgggga actgcatgag ctgcacgctg
     2461 ccctgcaacg tcgcctggat gaactgctgc ccgttggcga tgagcgggat cgggtcagca
     2521 gcgcaatgcg cgaaggcgta ctggcaccgg ggaaacgcat tcgcccgctg ctcctgatcc
     2581 tcgccgcccg cgacctcggc tgcgatcgcg accaccccgg cctgctggat atggcctgtg
     2641 cggtggaaat ggtgcacgcc tcgtcgctga tcctcgacga tattccctgc atggataacg
     2701 cggcgctccg gcgcggtcgc cctaccattc atcgccagta tggtgaagac gtggcaattc
     2761 tcgctgcggt agcgttgctc agcagcgcct ttggcgtgat ggtcgcggcg cagggattgt
     2821 ctcccgagtg ccgcagccag gcggtggcgg agctgtcgat ggcggtcggt acccagggtc
     2881 tggtgcaggg tcagtataag gatctgcgtg aaggcaccgc cccgcgcagc gccgaggaga
     2941 tcgccaccac caacgaactg aaaaccagcg tgctgtttgg tgccacgctg caaatcgcgg
     3001 ccctggcggc aggcgcctcg ccggcggcgc gccagaaaat gcgctgcttt gcgcaggatt
     3061 taggccaggc gttccagctg ctggacgatc tggcggacgg ccatgccggg accggcaaag
     3121 acatcaataa ggacgcgggt aagtccacgc tggtggcgat gctcggcagc gacgcggtgc
     3181 gcgagcggct cgacacccat ctgcgccgcg cagacgccca tttttcacgc gcctgcggaa
     3241 aaaaccaggc cacgcgacgc tttatgcacg cctggttttc aaaacagctg gccgcgttta
     3301 gctgagcaac ggatacaccc cggtaatatt tgtggagatc acatgaagga cgcgcatctg
     3361 gttcagcgta aaaatgacca cctggatatc gtgctgcacc ctgaccgggc gatgagtacc
     3421 attcgcaccg gatttgacgc ctggcgtttt gaacactgcg ccctcccgga gctggatctc
     3481 gacggtatcg atctctccac caccctgttt tcccgcccgc tgaaagcccc ggtgctgatc
     3541 agctccatga ccggcggcgc ggcgcgcgcc agagacatta accgtcatct ggcccaggcg
     3601 gcgcaaaccc ttgggctggc gatgggcgtc ggttcccagc gcgtggcgct ggaggacggc
     3661 gcgcagcacg ggctggatgc ccagctacgc catatcgccc cggacgtgcc gctgctggct
     3721 aaccttggcg cggcgcagat ccgcggtgcg caggggctgg actacgcccg gcgcgcggtg
     3781 gacatgatcg acgccgacgc gttaattgtg catctgaacc cgctgcagga ggcgctccag
     3841 ggcggcggcg atcgcgactg gcgcggcatc ctcaacgcca ttgcgcagct ggtgcgcgac
     3901 ctgccggtac cggtggtggt taaagaggtg ggcgccggga tctccccgga cgttgcctgc
     3961 cgactggcgg acgtcggcgt ggcgatgatc gacattgccg gcgcgggcgg aaccagctgg
     4021 gcggcggtgg aagctgaacg cgccccgacc cccgaggcgc gaaatgtggc gatggccttt
     4081 gccgactggg gcattcctac tgccgatgcg ctgcgtcgcg tccatcttgc gctgcctgat
     4141 atcccgctta tcgcctccgg cggcatcgcc aacggcattg acgcagcaaa agccatcgcg
     4201 ctgggtgcag atctggtggg ccaggccgcg gcggtgctgg cgcatgccaa cgcctccggc
     4261 gacgcggcaa ttgcccattt ccgcaccctg attacgcagc tgcggatcgc ctgtttctgt
     4321 accggcagtg caaacctgca ggcgttgcga cacgccacgc tgcttccggt caacggcggc
     4381 gcatccctgt gacgcagtac ggtgccttat accggggagc ggtatgaaaa aatgggatct
     4441 gattctggtc ggcgcggggc tggccaacgg gcttatcgcc tggcgactaa agcagcgtca
     4501 tccgacgctt gctgtattaa tgctggagtg cggcgacgcg cccggcggaa accacacctg
     4561 gtcctttcac caacacgata tcacgccagc ccagcacgcc tggctggcgc cgctggtggc
     4621 ccatcgctgg gacgggtacg acgtccactt tccgaacgtg tcgcgcaccc tgcatgacgg
     4681 ctacctgacc atcacctcca cgcgttttgc ccaagcgatg cgcgggctga tgaaagagaa
     4741 tttgctgaca aacgtgaccg tgtcacgggt gagcgggcag gaagtaaccc tcagcgacgg
     4801 acgacgcttt accgccgggg cggtgattga tggccgcggc tatcagccct cgccgcacct
     4861 cagcattggc tatcaggcgt tcatcggcca ggagtggcaa ctgaccgcgc cccacgggtt
     4921 aacgcgcccg atcctgatgg atgcccgcgt cgcccagggc aacggctacc gctttgtcta
     4981 taccctgccg ctcagcgccg acaccctgct tatcgaagac acgcactaca ttgacggccc
     5041 gacgctcgac gccgattcag cccgcgcgcg gattgccgat tacgcccgcc agcagggctg
     5101 gcagcttgcg cggctggtgc gtgaggaaca gggggcgctg ccgatcaccc tgtccggcga
     5161 tccggccgcc ttctggcacc agttccatca tcagccggtc agcggcctgc gcgccggtct
     5221 gttccatgcc accaccggct attcgctgcc gctggcggtt cggctggcgg accgcattgc
     5281 caacgcgccg ggactgcatc agggcgcgct ctatcagctg atcgccgatt tcgcggcgcg
     5341 ccactggcag acacaacgct ttttccgcct gcttaaccgc atgcttttcc tggccggcac
     5401 acccgaccag cgctggcgcg tgatgcagcg gttttaccag cttgacgagc agctgatcgc
     5461 ccgtttttat gccggccagc ttcgctccgc cgaccgcgcg cgcctgctgc ttggcaaacc
     5521 gccggtgccg attgtcgggg cgatcaaagc cctgctccac actcattctt ctctgcgagc
     5581 ccatcataaa tgaaacaaac cattgtaatt ggcgccgggt tcggcggact ggcgctggcg
     5641 attcgcctcc aggcggcggg cattcctacc acgctgctgg agagccgcga caaacccggc
     5701 ggccgcgcct atgtctacga agatcgcggc tttacctttg atgcgggtcc caccgtcatc
     5761 accgatccct ccgccattga ggagctgttc accctcgccg gaaaacggct gaaggactac
     5821 gttgagctga tgccggtgac gccgttctat cgcctgtgct gggaagacgg caaggttttc
     5881 gactacgcca acgatcaggc ggcgcttgag tcgcagatcg ccgcgtttaa cccgaacgac
     5941 gtggcgggct atcaccgctt cctcgactac tcccgggcgg tgtttgccga aggctatctg
     6001 aagctcggcg cggtgccgtt tctctcgttt cgcgacatgc tgcgcgccgg tcctcaactg
     6061 gcgcggctgc aggcatggcg cagcgtgtac gacaaagtgt cggcctacgt ggaagacgag
     6121 cacctgcggc aggcattttc gtttcactcg ctgctggtgg gcggcaaccc gttctccacg
     6181 tcttctattt acaccctgat ccacgccctg gagcgggaat ggggcgtctg gttcccgcgc
     6241 ggcggcaccg gtgcgctggt tcagggcatg gtgaagctgt ttcaggatct tggcggcacc
     6301 ctcaccctta acgctcaggt tgagcggctg gagacggtgg acaatcaggt gaaggccgtg
     6361 catctggtta acgggcagcg gctggaggct gcggcggtgg cctcgaacgc ggacgtggta
     6421 aatacctatg cccgactgct cggccatcac ccgcacggcg ccgctacggc caaaaagctg
     6481 aaacgcaagc gcatgagcaa ctcgctgttc gtgctctatt ttggcctgga tcaccatcac
     6541 acccagctgg cgcaccatac cgtctgcttt ggcccgcgtt ataaagcgct aatcgatgaa
     6601 attttcagcg ccgacaccct gtcggaagat ttttcgctct atctgcatgc gccctgcgta
     6661 accgacccgt cgctggcccc gccggggtgc ggcagctact atgtgctcgc gccggtgccg
     6721 cacctcggta acgccccgct cgactggagc gtggaagggc cgcgtctgcg ggatcgcatt
     6781 tttgattatc tcgaagcgcg ctatatgccg gggctgcgct cccagctggt gacgcaccgc
     6841 atgttcacgc cggaagattt tcgcgatacg ctcgatgcct ggcaggggtc agcgttttca
     6901 ctggagccga tcctcaccca gagcgcctgg ttccggccgc acaaccgcga cagcgtggtt
     6961 gataacctct acctggtcgg cgccggaacg catcccggcg ctggcgtgcc gggcgtgatc
     7021 ggatccgcca aggcaacggc ccagttaatg ttaaaggatt tagcgtaatg tcccagccgc
     7081 ttctcgaaca cgccagcgcc accatgaccg ccggttctaa aagtttcgcc accgcctcaa
     7141 agctgtttga caaacgcacc cggcgcagcg cgctgatgct ctatacctgg tgccgctact
     7201 gcgacgatgt tatcgacgga caggtggtgg gttttgctgc cccgaccgag cagagcgaca
     7261 cgcccgaggc gcgcctgcaa cggctgcgta agatgacgcg ccgcgcctac gacggggaaa
     7321 ccatgcaaga gccgccgttc gccgcctttc aggaggttgc cctcgcccat gccattccgc
     7381 ctactcaggc cttcgaccac ctggaaggct atgcgatgga cgtgcgcaac gagcgctatt
     7441 acagcctcga tgatacgctc cgctactgtt atcacgtggc gggcgtggtc ggcctgatga
     7501 tggccagggt gatgggagtg cgggacgaag ccacgctgga tcgcgcctgc gatctgggca
     7561 ttgcctttca gctcaccaat atcgccaggg atatcgttga cgatgcgcag gtgggacgct
     7621 gctacctgcc gcagcagtgg ctggcggaag tcggactcaa tgaacagacc tgcaccgtgc
     7681 gggccaaccg tccggcgctg gcgcgtctgg cagcgcggct ggtgaccgag gctgagccct
     7741 attatcagtc agcgcttgcc gggctggggg atctgcccct gcgctccgcc tgggcgattg
     7801 ccaccgcgca cggggtgtat cgtgagatcg gggtgaaggt gctgatggcg ggtgaaaaag
     7861 catgggatac ccgccagggc acgacgcgcg cggagaagct ggcgctggtt atttccggcg
     7921 cgaagcaggc gatggcttcc cggaaggcga gctggccgcc gcgcgatccg cacctctggc
     7981 agcgcccgcg ctagcgggtc tgccgttacg ttcgcgcagc accgcctgca gcttgtccac
     8041 cggtggggcg tagataaacc cgaaggagac gcacccttcg cgcccccgca ccgcgtgatg
     8101 cagccggtgt gccatgtaga ggcggcgcag atagccgcgg cgcggcacgt aacggaacgg
     8161 ccagcgctgg tggactaaac catcgtgaac gataaagtag atcacgccgt agccggtcat
     8221 tcccgcgcca atccactgaa gcggccagta cccttcgctg cccgcgtaaa tcagcgcaat
     8281 ggccagtagc gcaaacacca ccgcatagag atcgttacgc tcaaacgccc ctttgcgcgg
     8341 ggtatggtgc gaatgatgcc agccccatcc ccagccgtgc atgatgtact tgtgtgcgaa
     8401 cgttgccacc ccttccatga tgatgatagt cagtagcacg atcccggtat tccacaacgc
     8461 aagcataggt ttttcctgta gttgacagcc cctaaagcgt agcctggaat gccaggaaac
     8521 ataagcgtaa cctcggggat aatgcgcttt tcaggcgtaa aagcatttat gacaattatt
     8581 catcgcgcca cgttcacgcc gtgacgccct gctcaccgcg cggcagcagc cgcatcggct
     8641 gataaacgcg cccggtttct gcgcgtcatc gcccggtgtg cgcggcgtca acgcaataaa
     8701 acttactttc aaaaggcggc ccgaaaaggc tacccttttt tattcttgtc atatactcga
     8761 tctaacctga attatcgccg taacgtaccg cttcttttga ggtaatcccg gagc
//
