LOCUS       BGC0000641              8675 bp    DNA     linear   BCT 06-DEC-2005
DEFINITION  Enterobacteriaceae bacterium DC416 carotenoid synthesis gene
            cluster, complete sequence.
ACCESSION   BGC0000641
VERSION     BGC0000641
KEYWORDS    .
SOURCE      Enterobacteriaceae bacterium DC416
  ORGANISM  Enterobacteriaceae bacterium DC416
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 20:06:59
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..8675
                     /db_xref="taxon:338906"
                     /mol_type="genomic DNA"
                     /organism="Enterobacteriaceae bacterium DC416"
                     /strain="DC416"
     protocluster    1..8675
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[3405:6979]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3406..6979
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..8675
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..8675
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000641"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..8675
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1209..2114
                     /gene="crtE"
     CDS             1209..2114
                     /codon_start=1
                     /function="converts farnesyl pyrophosphate (FPP) to
                     geranylgeranyl pyrophosphate (GGPP)"
                     /gene="crtE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 170.1; E-value:
                     9.3e-52)"
                     /gene_kind="biosynthetic-additional"
                     /note="GGPP synthase"
                     /product="geranylgeranyl pyrophosphate synthase"
                     /protein_id="AAZ73139.1"
                     /transl_table=11
                     /translation="MTAHVDTTASQESDLLQLHHALQAHLEHLLPAGQQADRVRAAMRA
                     GTLAPGKRIRPLLLLLAARDMGCDVAQQGILDLACAVEMVHAASLILDDIPSMDNARMR
                     RGRPAIHCEYGENVAILAAVALLSRAFEVIALAPGLPATHKAEAIAELSSAVGLQGLVQ
                     GQFQDLHDGAHSRSPEAITLTNELKTSVLFRATLQMAAIAADASVQVRQRLSYFAQDLG
                     QAFQLLDDLADGSKHTGKDCHQDQGKSTLVQMLGPEGAERRLRDHLSSADAHLACACHR
                     GVATRQYMHALFNQQLAMFN"
     misc_feature    1209..7454
                     /note="carotenoid synthesis gene cluster"
     gene            2129..3406
                     /gene="crtX"
     CDS             2129..3406
                     /codon_start=1
                     /function="converts zeaxanthin to zeaxanthin glucosides"
                     /gene="crtX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 194.5;
                     E-value: 5.7e-59)"
                     /gene_kind="biosynthetic-additional"
                     /note="glucosylase"
                     /product="zeaxanthin glucosyl transferase"
                     /protein_id="AAZ73140.1"
                     /sec_met_domain="MGT (E-value: 2.5e-32, bitscore: 101.2,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGHFAVIAPPLYSHFHALQALAQTLLARGHRITFIQQSDARTLLS
                     DERIAFVAVGERTHPAGSLSSELRRLAAPGGLSLFRVIHDLASTTDMLCRELPAVLQRL
                     QVDGVIADQMEAAGGLVAEALQLPFVSVACALPVNREAAIPLVVMPFRFAQDEKALQRY
                     QASSDIYDRIMRRHGAVIARHARAFGLPERHGLHQCLSPLAQISQLVPAFDFPRQQLPA
                     CYHSVGPLRTPVASGALAAPWPALRQPVVYASLGTLQGHRFRLFLHLAQACRNQQLSLV
                     VAHCGGLTASQAHQLRLAGAAWVTDFVDQRAALQHAQLFITHAGLNSALEALECGTPML
                     ALPIAFDQPGVAARIEWHGVGRRASRFSRVAQLEHHLQQLLSDDRYRLRMSAIQAQLQR
                     AGGCTRAADIVEQALCQQQIVLAEAT"
     gene            3406..4572
                     /gene="crtY"
     CDS             3406..4572
                     /codon_start=1
                     /function="catalyzes the terminal cyclization reaction from
                     lycopene to beta-carotene"
                     /gene="crtY"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /product="lycopene cyclase"
                     /protein_id="AAZ73141.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 7.2e-127,
                     bitscore: 412.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAPYDVILVGAGLANGLIALRLRQLQPALKVLLLESQAQPAGNH
                     TWSFHREDVSEAQFRWLEPLLSARWPGYQVRFPTLRRQLDGEYCSIASEDFARHLQQVL
                     GAALRTAAPVSEVSPTGVRLADGGMLQAQAVIDGRGLQPTPHLQLGYQAFVGQEWQLAA
                     PHGLQQPILMDASVDQQQGYRFVYTLPLSASRLLIEDTHYINHATLDAAQARRHITDYA
                     HQRGWNLRQLLREEHGSLPITLSGDIDQFWQQQHGQPCSGLRAGLFHATTGYSLPAAVA
                     LAEKIASTLPADAHTLSHCIESFARQHWREQRFFRLLNRMLFLAGRPEQRWRVMQRFYR
                     LDAGLISRFYAGQLRLSDKARILCGKPPVPLGEALRALMMTSPLPGKK"
     gene            4572..6053
                     /gene="crtI"
     CDS             4572..6053
                     /codon_start=1
                     /function="desaturates phytoene to lycopene"
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 440.1; E-value: 2.1e-133)"
                     /gene_kind="biosynthetic-additional"
                     /product="phytoene desaturase"
                     /protein_id="AAZ73142.1"
                     /transl_table=11
                     /translation="MKRTYVIGAGFGGLALAIRLQAAGVPVTLLEQRDKPGGRAYVYQD
                     QGFTFDAGPTVITDPSAIEALFTLAGKQLSDYVDLMPVTPFYRLCWEDGRQLDYDNNQA
                     QLEQQIATFNPQDVAGYRQFLAYSQDVFREGYLKLGTVPFLHFRDMLRAGPQLGRLQAW
                     RSVYSMVAKFIHDDHLRQAFSFHSLLVGGNPFATSSIYTLIHALEREWGVWFPRGGTGA
                     LVDGMARLFRDLGGELLLNAEVSQLETEGNRISGVQLKDGRRFAAAAVASNADVVHTYD
                     RLLSQHPAARKRAATLKRKRMSNSLFVLYFGLNHAHPQLAHHTVCFGPRYRELIDEIFN
                     SSQLAEDFSLYLHAPCSSDPSLAPAGCGSFYVLAPVPHLGTAAIDWQQEGPRLRDRIFA
                     YLEEHYMPGLRQQLVTHRMFTPFDFRDTLHAHQGSAFSLEPILTQSAWFRPHNRDADIT
                     NLYLVGAGTHPGAGVPGVIGSAKATAQLMVEDLTG"
     gene            6050..6979
                     /gene="crtB"
     CDS             6050..6979
                     /codon_start=1
                     /function="converts two molecules of geranylgeranyl
                     pyrophosphate (GGPP) to phytoene"
                     /gene="crtB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /product="phytoene synthase"
                     /protein_id="AAZ73143.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.4e-53, bitscore:
                     168.9, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQPPLIEQVTQTMAQGSKSFASATRLFDPSTRRSTLMLYAWCRH
                     CDDVIDGQTLGEGGTQHAVADAQARMRHLQIETRRAYSGAHMDEPAFRAFQEVALTHQL
                     PQQLAFDHLEGFAMDAREERYACFGDTLRYCYHVAGVVGLMMARVMGVRDERVLDHACD
                     LGLAFQLTNIARDIVEDAENGRCYLPQSWLDEAGLSAAQLADPQHRAALAPLAARLVRE
                     AEPYYQSARSGLPGLPLRSAWAIATARGVYREIGVKVQHAGARAWDTRQRTSKGEKLAL
                     LVKGAGVALTSRLAHPEARPAGLWQRPR"
     CDS             complement(6918..7454)
                     /codon_start=1
                     /function="catalyzes the hydroxylation reaction from
                     beta-carotene to zeaxanthin"
                     /product="beta-carotene hydroxylase"
                     /protein_id="AAZ73144.1"
                     /transl_table=11
                     /translation="MMLWLWNALILLATVILMEIVAALSHKYIMHGWGWGWHLSHHEPH
                     ESKFELNDLYAVVFALLSIGLIWLGVNGVWPLQWIGAGMTTYGALYFMVHDGLVHQRWP
                     FRYIPRKGYLKRLYMAHRMHHAVRGREGCVSFGFLYAPPLHKLQATLRQRHGRRVNADA
                     ATDRQDAPRDEQGAK"
ORIGIN
        1 aacccgggct aatgggggtg acaagcccca ggccggccaa acaatcaggt ggaagggccc
       61 ggtgccgagg caatttgctc gatttgcaac gcaccagccg tggcaaacag cgcacggtag
      121 cgctcacgaa actgatcggc gatggcacta tgagtcgacg gcggagcgcc cggatcggcc
      181 aggtgatcga gatccagcgc ctgtaacagt aaccgcccgc cgccgtccgg ccgcacgttc
      241 agctgcggag aaatcaggtt ggtgccaagc gataacggct gtggtgcggt gcgcgccaga
      301 aagctgcagg ccaccgcatc aggcttgctg gtgtcaatca gcgccagttc cagaccaagc
      361 gtatgcagca gctgattggc ccagcgtccg gtcgccagca ccagacgatc accctgccac
      421 cgctcaccct gctccagctg caccgtcacg ccttccgcat tttcactaat gtgctgaatc
      481 gcctgatgct gatgcagtac cgcgccgtgc gcctgcgcct ctgaccacag ccgtgccaga
      541 tacagcgctg gatagagcac cgattccgtt ggaaaatgcc agatgctgcc gtgtaccgca
      601 gacgcgcgca gttcaggaat ttcctgctgc agctcggcca gcgtcctttg ccgtgccgca
      661 tagccagcgg cctgcaaggc ggtggcacgc tgctgcagtt gctgttcggc ttcacccgtg
      721 ccggcccact cccaggtgcc acaaggttcc agccagcgca cgccattggt ctgcgtcagc
      781 tgcagccgga tatgctcctc catcgccagc gcattgaggc ggtgatagct ggcaggctgt
      841 tttccgttgg agtttaccca ggcaaatgtg gtgctgctgg tgcccgcgcc catgtgttgc
      901 cggtcaaaga gggtcacctg cgccccctgc cgcgccagcg cccacgccac ggcgaggccg
      961 atcacacccg caccgattac cgccactttt tgcgtcgtca tagctgtctc ctctgctcgc
     1021 ccaacatcat aacagtcacc gcagcgaaaa ctggcctgag ggtcatagga attacttctc
     1081 agattattca ataaataaaa aaagcgtgac ggtgcgttaa agtcgcttcg ctcgctggcg
     1141 cactcccctt accgggtcta cggttaattg aaaaagcaca agaatttaac taaccatgga
     1201 aagccgctat gaccgcccat gtcgatacca cagcaagcca ggaaagcgat ctccttcagt
     1261 tgcatcacgc attgcaggcc catcttgaac atttattgcc tgccgggcag caggccgatc
     1321 gcgttcgggc cgccatgcgt gccggcacgc tggcaccggg caaacgtatt cgtccgctct
     1381 tgctgctgct ggcagcacgc gatatgggct gtgacgtggc gcagcagggc atccttgatc
     1441 ttgcctgtgc ggtcgaaatg gtgcacgctg cctcactgat cctcgacgac attccatcaa
     1501 tggataacgc ccggatgcga cgtgggcgcc cggcaatcca ctgtgaatat ggggaaaacg
     1561 tggcgatcct ggcagcggtc gcgctactca gccgcgcctt tgaggtgatt gccctcgcgc
     1621 cgggtctgcc agcaacgcac aaagccgaag ccattgccga gctctcctct gccgtgggcc
     1681 tgcagggact ggttcagggt cagttccagg atctgcatga cggcgcacac agccgcagtc
     1741 cggaagccat caccctgacc aatgaactga aaaccagcgt cctgtttcgc gccacgctgc
     1801 agatggcggc gattgcggcc gatgcgtcag tgcaggtacg tcagcgttta agctattttg
     1861 cgcaggattt aggtcaggct ttccagttac tggacgacct ggcggatggc tctaagcaca
     1921 ccggcaagga ctgtcatcag gatcagggca aatccacgct ggtgcagatg ctgggcccgg
     1981 aaggggctga gcgtcgtctg cgcgaccatc taagcagcgc cgatgcacac cttgcctgcg
     2041 cctgccatcg cggtgtcgcc acccgtcaat atatgcacgc cctgtttaat caacagctgg
     2101 cgatgttcaa ctgaagccgg tcatacctat ggggcatttt gccgttattg cgccaccgct
     2161 ctacagccac tttcacgcat tgcaggcgct ggcgcaaacg ctgctggcgc gcggacatcg
     2221 catcaccttt atccagcaaa gtgatgcacg caccttgctg agcgacgagc gcattgcctt
     2281 tgtggccgtc ggcgagcgca cgcatcctgc cggatcgctc tccagcgaac tcaggcggct
     2341 ggccgcaccg ggcgggctgt cgctgtttcg cgtgattcac gatctggcca gcaccaccga
     2401 tatgctatgc cgcgaactgc ccgcggtgct gcaacggctg caggtcgatg gcgtgattgc
     2461 cgatcaaatg gaagcggctg gtggtctggt ggcagaggcg ttacagctgc cgttcgtgtc
     2521 ggtggcctgc gcgctgccgg tcaatcgcga agcggccatt ccgctggtgg tgatgccctt
     2581 tcgctttgct caggatgaga aagcgctgca gcgctatcag gccagcagtg acatctacga
     2641 ccgcatcatg cgtcgtcatg gcgctgtcat cgctcgtcat gcgcgcgcct tcggcctgcc
     2701 cgaacgccat ggcttacatc agtgtctgtc gccgctggcg caaatcagtc agctggtgcc
     2761 cgcttttgat tttccacgcc agcaactgcc agcctgctat cacagcgtgg gtccgctgcg
     2821 gactccagtt gctagcggcg cgctcgccgc accctggcca gcgctgcgcc agccggtggt
     2881 gtatgcctcg ctgggcacgc tacaggggca tcgctttcgc ctgtttctgc atctggctca
     2941 ggcctgccgc aatcagcagc tgtcgctggt ggtggcacac tgtggcgggt tgaccgccag
     3001 ccaggcacat cagctcagac tggccggtgc tgcgtgggtg accgattttg tggatcagcg
     3061 ggcggcgctg cagcatgcgc aactgtttat cactcacgcc ggtctgaaca gtgcgctgga
     3121 agcactggag tgtggcacgc cgatgctggc gctgccgatc gccttcgatc agcccggcgt
     3181 ggcggcacgt attgagtggc acggcgtcgg ccggcgcgcc tcacgtttca gccgggtcgc
     3241 gcagctggag caccacctgc aacagttgct gagtgacgat cgctatcgtc tgcgcatgtc
     3301 agccattcag gcgcagctgc agcgggccgg tggctgtacg cgcgcggctg atattgtcga
     3361 gcaggcgctg tgtcagcagc aaatcgtgct ggcggaggcc acctgatgcg cgcaccttat
     3421 gatgtcattc tggtcggtgc cggcctggct aacgggctga ttgcgctgcg tttacgccag
     3481 ctgcagcccg cacttaaggt tttgctactg gagagtcagg cgcagccggc cggcaatcat
     3541 acctggtcgt tccatcgcga agacgtcagc gaagcgcagt ttcgctggct cgagccgctg
     3601 ctttcggcgc gctggcccgg ttatcaggta cgcttcccca ccctgcgtcg ccagctggat
     3661 ggtgaatatt gctcgattgc ctcggaggat tttgcccggc acttacagca ggtgctcggt
     3721 gccgcgctac gcaccgcagc gccggtcagc gaggtctcac ccaccggggt cagactggcg
     3781 gatggcggga tgttacaggc gcaggcggtg attgacggac gcgggctgca gccgacaccg
     3841 catctgcagc tcggctatca ggcatttgtc ggtcaggagt ggcaactggc cgcgccgcat
     3901 ggcctgcagc agccaatatt gatggacgcc agcgtcgatc agcagcaggg ttatcgcttt
     3961 gtttacaccc tgccgctcag tgccagccgt ttactgattg aagataccca ctacatcaac
     4021 catgccacgc tggatgccgc acaggcgcgc cgtcacatta cggattatgc ccaccagcgc
     4081 ggctggaatt tgcgccagct gctgcgcgag gagcacggct cgctgccgat cacgctcagc
     4141 ggcgatatcg atcagttctg gcaacagcag cacgggcaac cgtgcagcgg gctgcgcgcc
     4201 ggactgtttc acgccaccac cggttactcg ctgcccgccg cggtggcgct ggcggagaag
     4261 attgccagca cgctgcccgc cgacgctcac acgctgagcc actgcatcga atcctttgcc
     4321 cgtcagcact ggcgcgagca gcgctttttc cgtctgttaa atcgcatgct gtttcttgcc
     4381 ggacggcctg aacagcgctg gcgcgtaatg cagcgttttt accggcttga cgccggattg
     4441 attagccgct tttacgccgg gcaactgcgc ctcagcgata aagcacgcat tctgtgcggc
     4501 aaaccgccgg tccctctcgg cgaagcgctg cgcgcattga tgatgacctc tccgttacca
     4561 gggaagaaat aatgaaacgc acctatgtga ttggcgcagg cttcggtggc ctggcgctgg
     4621 cgattcgtct gcaagcggcc ggcgtgccgg tcacgctgct ggaacagcgc gataagcctg
     4681 gcgggcgcgc ctatgtgtat caggatcagg gttttacctt tgatgccggt ccgacggtga
     4741 ttaccgatcc cagcgctatc gaggcgctgt ttacgctggc aggcaagcaa ctcagtgatt
     4801 atgtcgacct gatgccggtg acgccatttt atcgcctgtg ctgggaagac ggcaggcagc
     4861 tggactacga caacaatcag gcgcagctgg agcagcagat tgccactttt aatccccagg
     4921 atgtcgccgg ttaccgccag tttctggcct attcacagga tgtgtttcgt gagggctatc
     4981 tgaaactggg caccgtacct tttctgcatt tccgcgacat gctgcgtgcc gggccacagc
     5041 tgggtcggct gcaggcctgg cgcagtgtct acagcatggt ggcgaaattt attcatgacg
     5101 atcatctgcg ccaggctttt tcctttcact cgttgctggt cggcggtaat ccttttgcaa
     5161 cgtcttcgat ctatacctta attcacgcac tggagcgcga atggggcgtg tggtttccgc
     5221 gcggcggtac cggtgcgctg gttgatggca tggcgcggct gtttcgcgat ttgggcggtg
     5281 aactgctgct caacgccgaa gtcagccagc tggagaccga gggtaaccgc atcagcggtg
     5341 tccagctgaa ggatgggcgc cgttttgccg ccgccgccgt tgcgtcaaat gctgacgtgg
     5401 tgcataccta cgatcgcctg ttaagccagc atcctgcggc gcgtaaacgc gcggcaacgc
     5461 tgaagcgcaa gcggatgagc aactcgctgt ttgtactcta ttttggtctt aatcatgccc
     5521 acccgcagct ggcgcaccac acggtgtgct ttggtccgcg ctatcgtgaa ttgatcgatg
     5581 agatcttcaa tagcagccag ctggcggaag atttctcgct gtatctgcat gcgccctgct
     5641 ccagcgatcc gtcgctggca ccggcgggct gcggcagttt ttacgtgctg gcgccggtgc
     5701 cgcatctcgg taccgccgca attgactggc aacaggaagg gccgcgcttg cgcgatcgca
     5761 tttttgctta tctggaggag cactatatgc cgggtctgcg acagcagtta gtgacacacc
     5821 gtatgtttac gccgtttgat tttcgcgaca cgctgcacgc gcatcagggc tcagcgtttt
     5881 cgctcgaacc cattttgacg caaagcgcct ggttccggcc gcataaccgc gatgccgaca
     5941 ttactaacct ttatctggtg ggggctggca cgcatcccgg tgccggtgtg ccaggcgtga
     6001 tcggctccgc gaaagcgacc gcccagctga tggtggagga tctgaccgga tgaaccaacc
     6061 gccgctgatt gagcaggtca cgcaaaccat ggcgcagggc tccaaaagtt tcgccagcgc
     6121 tacccggcta tttgatcctt caacgcgccg cagtacgctg atgctgtacg cctggtgtcg
     6181 tcactgtgac gatgtgatag atggtcagac gctgggcgaa ggcggcacgc agcacgcggt
     6241 ggcggatgca caggcgcgga tgcgccacct gcaaatcgaa acccgccgcg cctacagcgg
     6301 tgcccacatg gatgaaccag cgtttcgtgc ctttcaggaa gtggcgctga cgcatcagct
     6361 tccccagcag ctggcttttg atcatctgga agggtttgcg atggatgcgc gtgaagaacg
     6421 ttatgcgtgt ttcggggaca cgctgcgtta ctgctatcac gtggccggcg tggtggggtt
     6481 aatgatggcg cgcgtgatgg gcgtacgtga tgagcgcgta ctcgatcacg cctgtgattt
     6541 gggtctggcg tttcagctta ccaatatcgc acgggatatc gttgaggacg cggagaatgg
     6601 ccgttgctat ctgccacaaa gctggctgga tgaggccgga ctgagcgccg cccagcttgc
     6661 cgatccgcaa catcgcgcag cgctggcccc gctggcagcg cgtctggtgc gcgaggccga
     6721 gccgtactat cagtcagcgc gcagcgggct gccaggattg ccgctccgtt cggcgtgggc
     6781 gatcgccacc gcgcgcggcg tttaccggga aattggcgta aaagtgcagc atgccggtgc
     6841 ccgggcatgg gatacgcgcc agcgcaccag taaaggcgaa aagctggcgc tgctggtgaa
     6901 aggtgccggc gtcgcgctta cttcgcgcct tgctcatccc gaggcgcgtc ctgccggtct
     6961 gtggcagcgt ccgcgttgac acgacgccca tggcgctggc gcagcgtcgc ctgcagcttg
     7021 tgcaacggtg gggcgtaaag aaagccaaag gaaacgcagc cttcccgtcc ccgcaccgca
     7081 tgatgcatgc ggtgcgccat atacaaccgc ttcagatagc ctttgcgtgg aatatagcga
     7141 aacggccagc gttgatggac caggccgtca tgcaccataa aatagagagc gccataggtc
     7201 gtcatgccag cgccaatcca ctgcagcggc cagacgccgt tgacacccag ccaaatcagg
     7261 ccaatcgaca acagcgcaaa caccacggca tacaggtcgt tgagctcaaa tttgctctca
     7321 tgtggttcat gatgcgacaa atgccagccc catccccagc catgcataat gtatttatgc
     7381 gacagcgccg cgacgatctc catcagtatc acggtagcca gcaggataag cgcattccat
     7441 aaccagagca tcattggtcc atttgcgaag agtgagagta taaaggtgga cgtggatagc
     7501 gaaaggcgca agtccccggc aaaaaaacgc accggcagcg taaataccag ccaggtcacg
     7561 gacgcgtgct atcaccttca gacaagcaaa gcggcaagag ggttatcctg catggcggcc
     7621 gggtgggtct gctttacatc gatttaacag ctggttagta tagccagcgg ttcagcggtc
     7681 caggctgctg cgtacgcgtt aacgtcaatc aacgcaccat atgcagagac tttctgcctc
     7741 atttctatgg tgcgcaacat gtcccatacc gctttatctg ctgattctgc cctgcgtcgt
     7801 tccggctttt tcctgctgct actgttactc accgccgcca acttacgcac gcccatcacc
     7861 gctaccgggc cggtactgga aaatattcgc ctgacatttg gcctgagcgc cagcgctgcc
     7921 ggcgtgatta actttttacc gctgctgatg tttgccacgc tggctccgcc agccgcctgg
     7981 tttggcaatc gctttggcct ggagcgcagt ctgtgggggg ctttactcct gatcgtcctg
     8041 ggttcactgc tgcgaatcag cggcagcgaa acggcactgt ggctgggtac gctgattctc
     8101 agcagcggga tcgcggcggc caacgtcctg ctgccgccgc tgattaagcg ggattacacc
     8161 gcgcacaccg cgcgttatat cgggctgtat gccatgacca tgggcatcac cgccagcatc
     8221 gcttccggcg tggccgtgcc gctggccgaa ctcagcagcg ccggctggcg tctgtcgctg
     8281 gcggtctggc tgattccggc tctggtcgcg ctactggcgt ggctgccgca gctgaaaaat
     8341 cccgcgacgc gtgagcagcg cgcgacagag gtcaccgtaa cgcgttcgcc gtgtcgttcc
     8401 gcgatcggct ggcaggtgtc gctgttcatg gccagccagt cgctgctgtt ttataccctg
     8461 attggctggt ttaccccgtt cgcacaggat aatggcatca gtcagcttca ggcaggcagc
     8521 atgttgtttg tctatcaaat tgtggcgatc gcctccaatc tggcctgtat gcgggcgctg
     8581 aagcagctgc gcgatcagcg tctgatcggg ctactggcct cgctgtcgat cttcatcgcg
     8641 gtgaccggcc tgctgctggc acccgcatgg tctct
//
