BGC0000646 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000646 (uncultured bacterium)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	terpene	1	6,380	High	β-carotein	terpene:Hemiterpene

BGC0000646 - Region 1 - terpene

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Location: 1 - 6,380 nt. (total: 6,380 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Terpene

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 6,381
Label		BGC0000646

Tailoring functions

Oxidoreductases: dehydrogenase

ACI04498.1: dehydrogenase

smcogs: SMCOG1222: dehydrogenase

Transferases: glycosyltransferase

ACI04501.1: glycosyltransferase, MGT family

smcogs: SMCOG1062: glycosyltransferase, MGT family

Ligases: synthetase

ACI04497.1: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000646.5	1.00	terpene	β-carotein	uncultured bacterium
BGC0000647.3	0.78	terpene	carotenoid	Rhodobacter sphaeroides
BGC0000656.5	0.75	terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000640.3	0.56	terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000643.3	0.55	terpene	carotenoid	Brevundimonas vesicularis
BGC0000634.3	0.55	terpene	carotenoid	Brevundimonas sp. SD212
BGC0000641.3	0.54	terpene	carotenoid	Enterobacteriaceae bacterium DC416
BGC0000630.3	0.54	terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000639.3	0.54	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000635.3	0.53	terpene	carotenoid	Paracoccus sp. N81106

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000646.5	1.00	terpene	β-carotein	uncultured bacterium
BGC0000647.3	0.78	terpene	carotenoid	Rhodobacter sphaeroides
BGC0000656.5	0.75	terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000640.3	0.56	terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000643.3	0.55	terpene	carotenoid	Brevundimonas vesicularis
BGC0000634.3	0.55	terpene	carotenoid	Brevundimonas sp. SD212
BGC0000641.3	0.54	terpene	carotenoid	Enterobacteriaceae bacterium DC416
BGC0000630.3	0.54	terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000639.3	0.54	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000635.3	0.53	terpene	carotenoid	Paracoccus sp. N81106

Similar known clusters from MIBiG 4.0

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
tetraterpene	C40 carotenoid		C40	unknown	unknown

Genes with terpene domains:

ACI04496.1: Lycopene_cycl

Domain 1 (14 - 380): Lycopene cyclase

Reactions:: C40_carotenoid → C40_carotenoid

ACI04497.1: PT_FPPS_like

Domain 1 (47 - 244): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

ACI04499.1: PT_phytoene_like

Domain 1 (4 - 286): Prenyltransferase; Phytoene synthase like

Subtype: unknown

Reactions:: FPP → squalene; FPP → PSPP; FPP → diapophytoene; GGPP → phytoene; PSPP → hydroxysqualene

Terpene

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PSPP	Presqualene diphosphate