BGC0000654: phenalinolactone A biosynthetic gene cluster from Streptomyces sp. Tu6071
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Location: 1 - 49,461 nt. (total: 49,461 nt).
This entry is originally from NCBI GenBank DQ230532.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000654
Short description phenalinolactone A biosynthetic gene cluster from Streptomyces sp. Tu6071
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • terpene (Diterpene)
  • saccharide (hybrid/tailoring)
Loci
DQ230532.1
via Knock-out studies, Heterologous expression
Compounds
  • phenalinolactone A
Species Streptomyces sp. Tu6071 [taxonomy]
References
Chemical products information
phenalinolactone A Evidence:
Copy SMILES
C38H53N1O12
Chemical database entries
NPAtlas
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABB69733.1
  • plaR1
 6556 - 7353 (-) PlaR1
  • Regulation
  • Knock-out
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  • ABB69734.1
  • plaR2
 7806 - 8408 (-) PlaR2
  • Regulation
  • Knock-out
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  • ABB69735.1
  • plaA1
 9161 - 10465 (+) PlaA1
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    • ABB69736.1
    • plaA2
    		 10462 - 11853 (+) PlaA2
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      • ABB69737.1
      • plaA3
      		 11866 - 12837 (-) PlaA3
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        • ABB69738.1
        • plaA4
        		 12837 - 13742 (-) PlaA4
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          • ABB69739.1
          • plaM1
          		 13739 - 14650 (-) PlaM1
          • Tailoring
          • Knock-out
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          • ABB69740.1
          • plaP6
          		 14589 - 15554 (-) PlaP6
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            • ABB69741.1
            • plaO1
            		 15554 - 16420 (-) PlaO1
            • Tailoring
            • Knock-out Activity assay
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            • ABB69742.1
            • plaT1
            		 16422 - 17771 (-) PlaT1
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              • ABB69743.1
              • plaT2
              		 17768 - 19483 (-) PlaT2
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                • ABB69744.1
                • plaT3
                		 19499 - 20512 (-) PlaT3
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                  • ABB69745.1
                  • plaH
                  		 20514 - 21398 (-) PlaH
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                    • ABB69746.1
                    • plaO2
                    		 21436 - 22629 (-) PlaO2
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                      • ABB69747.1
                      • plaM2
                      		 22884 - 23729 (+) PlaM2
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                        • ABB69748.1
                        • PlaO3
                        		 23753 - 24958 (+) PlaO3
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                          • ABB69749.1
                          • plaP1
                          		 25098 - 25388 (+) PlaP1
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                            • ABB69750.1
                            • plaP2
                            		 25401 - 26468 (+) PlaP2
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                              • ABB69751.1
                              • plaP3
                              		 26458 - 27591 (+) PlaP3
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                                • ABB69752.1
                                • plaP4
                                		 27588 - 29372 (+) PlaP4
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                                  • ABB69753.1
                                  • plaP5
                                  		 29386 - 31092 (+) PlaP5
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                                    • ABB69754.1
                                    • plaT4
                                    		 31153 - 32232 (+) PlaT4
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                                      • ABB69755.1
                                      • plaT5
                                      		 32273 - 33433 (+) PlaT5
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                                        • ABB69756.1
                                        • plaT6
                                        		 33430 - 35211 (+) PlaT6
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                                          • ABB69757.1
                                          • plaU
                                          		 35268 - 36002 (+) PlaU
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                                            • ABB69758.1
                                            • plaV
                                            		 36051 - 37505 (-) 3-O-acetyl transferase
                                            • Tailoring
                                            • Knock-out
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                                            • ABB69759.1
                                            • plaO4
                                            		 37551 - 38726 (-) PlaO4
                                            • Tailoring
                                            • Knock-out
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                                            • ABB69760.1
                                            • plaA5
                                            		 38851 - 39858 (+) PlaA5
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                                              • ABB69761.1
                                              • plaA6
                                              		 41235 - 42425 (+) PlaA6
                                              • Tailoring
                                              • Knock-out
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                                              • ABB69762.1
                                              • plaA7
                                              		 42464 - 43399 (-) PlaA7
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                                                • ABB69763.1
                                                • plaA8
                                                		 43419 - 43994 (-) PlaA8
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                                                  • ABB69764.1
                                                  • plaO5
                                                  		 44294 - 45523 (+) PlaO5
                                                  • Tailoring
                                                  • Knock-out Activity assay
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                                                  • ABB69765.1
                                                  • plaM3
                                                  		 45600 - 46412 (+) PlaM3
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                                                    • ABB69766.1
                                                    • plaR3
                                                    		 47334 - 47693 (-) PlaR3
                                                    • Regulation
                                                    • Knock-out
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                                                    • ABB69767.1
                                                    • plaZ
                                                    		 47763 - 48476 (+) PlaZ
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                                                      Biosynthesis information
                                                      Annotation changelog

                                                      Entry version: 3

                                                      Date
                                                      Changes
                                                      Submitters
                                                      Reviewers
                                                      2022-10-07
                                                      Update chemical activity to schema version 2.11
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                      Entry version: 2

                                                      Date
                                                      Changes
                                                      Submitters
                                                      Reviewers
                                                      2019-10-16
                                                      Migrated from v1.4
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      2019-10-16
                                                      Updated compound(s) information (NPAtlas curation)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                      Entry version: 1

                                                      Date
                                                      Changes
                                                      Submitters
                                                      Reviewers
                                                      2015-06-12
                                                      Submitted
                                                      • (ID: LPHAMZXQ3BT6INJWOLKUYGWU)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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